1URBA

Alkaline phosphatase (n51mg)
Total Genus 163
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
163
Knots found
sequence length
446
structure length
446
Chain Sequence
MPVLENRAAQGDITAPGGARRLTGDQTAALRDSLSDKPAKNIILLIGNGMGDSEITAARNYAEGAGGFFKGIDALPLTGQYTHYALNKKTGKPDYVTDSAASATAWSTGVKTYNGALGVDIHEKDHPTILEMAKAAGLATGNVSTAELQDATPAALVAHVTSRKCYGPSATSEKCPGNALEKGGKGSITEQLLNARADVTLGGGAKTFAETATAGEWQGKTLREQAQARGYQLVSDAASLNSVTEANQQKPLLGLFADGNMPVRWLGPKATYHGNIDKPAVTCTPNPQRNDSVPTLAQMTDKAIELLSKNEKGFFLQVEGASIDKQDHAANPCGQIGETVDLDEAVQRALEFAKKEGNTLVIVTADHAHASQIVAPDTKAPGLTQALNTKDGAVMVMSYGNSEEDSQEHTGSQLRIAAYGPHAANVVGLTDQTDLFYTMKAALGLK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule keywords ALKALINE PHOSPHATASE
publication title Kinetic and structural consequences of replacing the aspartate bridge by asparagine in the catalytic metal triad of Escherichia coli alkaline phosphatase.
pubmed doi rcsb
source organism Escherichia coli
molecule tags Alkaline phosphatase
total genus 163
structure length 446
sequence length 446
chains with identical sequence B
other databases KnotProt 2.0: S +31
ec nomenclature ec 3.1.3.1: Alkaline phosphatase.
pdb deposition date 1996-02-03

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00245 Alk_phosphatase Alkaline phosphatase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.720.10 Alpha Beta 3-Layer(aba) Sandwich Alkaline Phosphatase, subunit A Alkaline Phosphatase, subunit A 1urbA00
3KD8A 2W5SA 2GLQA 4UOOA 4N7TA 2W5TA 2IUCB 1N2KA 3MK0A 4KAYA 5HRTA 4MHXA 4MIVA 1K7HA 4CXKA 1ALIA 2G9YA 4KJGA 1KH9A 4LQYA 1P49A 4UOPA 3T02A 4CYRA 3UN2A 4GTXA 5DLWA 3UN3A 1SHNA 5TJ3A 4TN0A 1ZEFA 4CYSA 2VQRA 3ED4A 1ELZA 2XRGA 4UORA 4YR1A 5DLVA 1E3CP 3TWZA 1ELYA 3NKPA 5LQQA 4GTYA 3IDDA 5IJQA 3SZZA 5C66A 3NKMA 5IJSA 1KH7A 2ZKTA 3LXQA 3WAWA 1ALHA 3NVLA 4ZG6A 1ALJA 2ANHA 1ELXA 3NKOA 5L0EA 1B8JA 4LRAA 3MK1A 4ZGAA 1O99A 2IUCA 3T00A 4NWXA 5GOVA 1ALKA 3WAXA 4LRBA 2GA3A 3TX0A 1URAA 1AJDA 1O98A 5L0BA 2W5XA 4LRCA 5K4PA 5AJ9A 3Q3QA 4LREA 1ZEDA 5EGEA 3M7VA 4CXUA 4LR2A 3NKNA 4UPLA 1ZEBA 3WAVA 2QZUA 1HDHA 5KXAA 4B56A 3OT9A 1KHNA 1EW9A 3E2DA 3UN5A 3DPCA 3M8WA 1E2SP 1AUKA 1EQJA 4GTWA 1ANJA 4KAVA 4QAXA 1ANIA 3DYCA 4LR8A 3M8ZA 3NKRA 1Y7AA 3M8YA 1FSUA 2W5VA 1Y6VA 1E33P 2W5RA 1EI6A 5INHA 1ED9A 4ZG7A 3UNYA 1EJJA 5LRMA 4FDJA 1EW8A 1KH5A 3BDGB 1N2LA 3CMRA 3BDFA 2W5QA 3B5QA 2W8SA 1E1ZP 3SZYA 4FDIA 4LRFA 1ED8A 3WBHA 3BDHA 2IFYA 5LRNA 3T01A 3MK2A 4CXSA 3UO0A 5LIAA 3IGZB 1URBA 5DLTA 4ZG9A 1KHLA 3NKQA 2RH6A 4GTZA 4LR9A 2GSOA 2D1GA 2W5WA 1SHQA 1HQAA 4KM4A 3WAYA 1HJKA 3IGYB 1AJAA 2XR9A 4KJDA 1EW2A 5L0KA 4MY4A 1AJBA 4UPKA 1KHJA 4LRDA 5EGHA 5GRRA 1KH4A 4NWJA 1AJCA 4LR7A 3TG0A 1KHKA 2W8DA 2GSUA 4UPIA 2X98A 3BDGA 3A52A 4UPHA 2GSNA
chains in the Genus database with same CATH superfamily
3KD8A 2W5SA 2GLQA 4UOOA 4N7TA 2W5TA 2IUCB 1N2KA 3MK0A 4KAYA 5HRTA 4MHXA 4MIVA 1K7HA 4CXKA 1ALIA 2G9YA 4KJGA 1KH9A 4LQYA 1P49A 4UOPA 3T02A 4CYRA 3UN2A 4GTXA 5DLWA 3UN3A 1SHNA 5TJ3A 4TN0A 1ZEFA 4CYSA 2VQRA 3ED4A 1ELZA 2XRGA 4UORA 4YR1A 5DLVA 1E3CP 3TWZA 1ELYA 3NKPA 5LQQA 4GTYA 3IDDA 5IJQA 3SZZA 5C66A 3NKMA 5IJSA 1KH7A 2ZKTA 3LXQA 3WAWA 1ALHA 3NVLA 4ZG6A 1ALJA 2ANHA 1ELXA 3NKOA 5L0EA 1B8JA 4LRAA 3MK1A 4ZGAA 1O99A 2IUCA 3T00A 4NWXA 5GOVA 1ALKA 3WAXA 4LRBA 2GA3A 3TX0A 1URAA 1AJDA 1O98A 5L0BA 2W5XA 4LRCA 5K4PA 5AJ9A 3Q3QA 4LREA 1ZEDA 5EGEA 3M7VA 4CXUA 4LR2A 3NKNA 4UPLA 1ZEBA 3WAVA 2QZUA 1HDHA 5KXAA 4B56A 3OT9A 1KHNA 1EW9A 3E2DA 3UN5A 3DPCA 3M8WA 1E2SP 1AUKA 1EQJA 4GTWA 1ANJA 4KAVA 4QAXA 1ANIA 3DYCA 4LR8A 3M8ZA 3NKRA 1Y7AA 3M8YA 1FSUA 2W5VA 1Y6VA 1E33P 2W5RA 1EI6A 5INHA 1ED9A 4ZG7A 3UNYA 1EJJA 5LRMA 4FDJA 1EW8A 1KH5A 3BDGB 1N2LA 3CMRA 3BDFA 2W5QA 3B5QA 2W8SA 1E1ZP 3SZYA 4FDIA 4LRFA 1ED8A 3WBHA 3BDHA 2IFYA 5LRNA 3T01A 3MK2A 4CXSA 3UO0A 5LIAA 3IGZB 1URBA 5DLTA 4ZG9A 1KHLA 3NKQA 2RH6A 4GTZA 4LR9A 2GSOA 2D1GA 2W5WA 1SHQA 1HQAA 4KM4A 3WAYA 1HJKA 3IGYB 1AJAA 2XR9A 4KJDA 1EW2A 5L0KA 4MY4A 1AJBA 4UPKA 1KHJA 4LRDA 5EGHA 5GRRA 1KH4A 4NWJA 1AJCA 4LR7A 3TG0A 1KHKA 2W8DA 2GSUA 4UPIA 2X98A 3BDGA 3A52A 4UPHA 2GSNA
chains in the Genus database with same CATH topology
3KD8A 2W5SA 2GLQA 4UOOA 4N7TA 2W5TA 2IUCB 1N2KA 3MK0A 4KAYA 5HRTA 4MHXA 4MIVA 1K7HA 4CXKA 1ALIA 2G9YA 4KJGA 1KH9A 4LQYA 1P49A 4UOPA 3T02A 4CYRA 3UN2A 4GTXA 5DLWA 3UN3A 1SHNA 5TJ3A 4TN0A 1ZEFA 4CYSA 2VQRA 3ED4A 1ELZA 2XRGA 4UORA 4YR1A 5DLVA 1E3CP 3TWZA 1ELYA 3NKPA 5LQQA 4GTYA 3IDDA 5IJQA 3SZZA 5C66A 3NKMA 5IJSA 1KH7A 2ZKTA 3LXQA 3WAWA 1ALHA 3NVLA 4ZG6A 1ALJA 2ANHA 1ELXA 3NKOA 5L0EA 1B8JA 4LRAA 3MK1A 4ZGAA 1O99A 2IUCA 3T00A 4NWXA 5GOVA 1ALKA 3WAXA 4LRBA 2GA3A 3TX0A 1URAA 1AJDA 1O98A 5L0BA 2W5XA 4LRCA 5K4PA 5AJ9A 3Q3QA 4LREA 1ZEDA 5EGEA 3M7VA 4CXUA 4LR2A 3NKNA 4UPLA 1ZEBA 3WAVA 2QZUA 1HDHA 5KXAA 4B56A 3OT9A 1KHNA 1EW9A 3E2DA 3UN5A 3DPCA 3M8WA 1E2SP 1AUKA 1EQJA 4GTWA 1ANJA 4KAVA 4QAXA 1ANIA 3DYCA 4LR8A 3M8ZA 3NKRA 1Y7AA 3M8YA 1FSUA 2W5VA 1Y6VA 1E33P 2W5RA 1EI6A 5INHA 1ED9A 4ZG7A 3UNYA 1EJJA 5LRMA 4FDJA 1EW8A 1KH5A 3BDGB 1N2LA 3CMRA 3BDFA 2W5QA 3B5QA 2W8SA 1E1ZP 3SZYA 4FDIA 4LRFA 1ED8A 3WBHA 3BDHA 2IFYA 5LRNA 3T01A 3MK2A 4CXSA 3UO0A 5LIAA 3IGZB 1URBA 5DLTA 4ZG9A 1KHLA 3NKQA 2RH6A 4GTZA 4LR9A 2GSOA 2D1GA 2W5WA 1SHQA 1HQAA 4KM4A 3WAYA 1HJKA 3IGYB 1AJAA 2XR9A 4KJDA 1EW2A 5L0KA 4MY4A 1AJBA 4UPKA 1KHJA 4LRDA 5EGHA 5GRRA 1KH4A 4NWJA 1AJCA 4LR7A 3TG0A 1KHKA 2W8DA 2GSUA 4UPIA 2X98A 3BDGA 3A52A 4UPHA 2GSNA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3KD8 A;  2W5S A;  2GLQ A;  4UOO A;  4N7T A;  2W5T A;  2IUC B;  1N2K A;  3MK0 A;  4KAY A;  5HRT A;  4MHX A;  4MIV A;  1K7H A;  4CXK A;  1ALI A;  2G9Y A;  4KJG A;  1KH9 A;  4LQY A;  1P49 A;  4UOP A;  3T02 A;  4CYR A;  3UN2 A;  4GTX A;  5DLW A;  3UN3 A;  1SHN A;  5TJ3 A;  4TN0 A;  1ZEF A;  4CYS A;  2VQR A;  3ED4 A;  1ELZ A;  2XRG A;  4UOR A;  4YR1 A;  5DLV A;  1E3C P;  3TWZ A;  1ELY A;  3NKP A;  5LQQ A;  4GTY A;  3IDD A;  5IJQ A;  3SZZ A;  5C66 A;  3NKM A;  5IJS A;  1KH7 A;  2ZKT A;  3LXQ A;  3WAW A;  1ALH A;  3NVL A;  4ZG6 A;  1ALJ A;  2ANH A;  1ELX A;  3NKO A;  5L0E A;  1B8J A;  4LRA A;  3MK1 A;  4ZGA A;  1O99 A;  2IUC A;  3T00 A;  4NWX A;  5GOV A;  1ALK A;  3WAX A;  4LRB A;  2GA3 A;  3TX0 A;  1URA A;  1AJD A;  1O98 A;  5L0B A;  2W5X A;  4LRC A;  5K4P A;  5AJ9 A;  3Q3Q A;  4LRE A;  1ZED A;  5EGE A;  3M7V A;  4CXU A;  4LR2 A;  3NKN A;  4UPL A;  1ZEB A;  3WAV A;  2QZU A;  1HDH A;  5KXA A;  4B56 A;  3OT9 A;  1KHN A;  1EW9 A;  3E2D A;  3UN5 A;  3DPC A;  3M8W A;  1E2S P;  1AUK A;  1EQJ A;  4GTW A;  1ANJ A;  4KAV A;  4QAX A;  1ANI A;  3DYC A;  4LR8 A;  3M8Z A;  3NKR A;  1Y7A A;  3M8Y A;  1FSU A;  2W5V A;  1Y6V A;  1E33 P;  2W5R A;  1EI6 A;  5INH A;  1ED9 A;  4ZG7 A;  3UNY A;  1EJJ A;  5LRM A;  4FDJ A;  1EW8 A;  1KH5 A;  3BDG B;  1N2L A;  3CMR A;  3BDF A;  2W5Q A;  3B5Q A;  2W8S A;  1E1Z P;  3SZY A;  4FDI A;  4LRF A;  1ED8 A;  3WBH A;  3BDH A;  2IFY A;  5LRN A;  3T01 A;  3MK2 A;  4CXS A;  3UO0 A;  5LIA A;  3IGZ B;  1URB A;  5DLT A;  4ZG9 A;  1KHL A;  3NKQ A;  2RH6 A;  4GTZ A;  4LR9 A;  2GSO A;  2D1G A;  2W5W A;  1SHQ A;  1HQA A;  4KM4 A;  3WAY A;  1HJK A;  3IGY B;  1AJA A;  2XR9 A;  4KJD A;  1EW2 A;  5L0K A;  4MY4 A;  1AJB A;  4UPK A;  1KHJ A;  4LRD A;  5EGH A;  5GRR A;  1KH4 A;  4NWJ A;  1AJC A;  4LR7 A;  3TG0 A;  1KHK A;  2W8D A;  2GSU A;  4UPI A;  2X98 A;  3BDG A;  3A52 A;  4UPH A;  2GSN A; 
#chains in the Genus database with same CATH topology
 3KD8 A;  2W5S A;  2GLQ A;  4UOO A;  4N7T A;  2W5T A;  2IUC B;  1N2K A;  3MK0 A;  4KAY A;  5HRT A;  4MHX A;  4MIV A;  1K7H A;  4CXK A;  1ALI A;  2G9Y A;  4KJG A;  1KH9 A;  4LQY A;  1P49 A;  4UOP A;  3T02 A;  4CYR A;  3UN2 A;  4GTX A;  5DLW A;  3UN3 A;  1SHN A;  5TJ3 A;  4TN0 A;  1ZEF A;  4CYS A;  2VQR A;  3ED4 A;  1ELZ A;  2XRG A;  4UOR A;  4YR1 A;  5DLV A;  1E3C P;  3TWZ A;  1ELY A;  3NKP A;  5LQQ A;  4GTY A;  3IDD A;  5IJQ A;  3SZZ A;  5C66 A;  3NKM A;  5IJS A;  1KH7 A;  2ZKT A;  3LXQ A;  3WAW A;  1ALH A;  3NVL A;  4ZG6 A;  1ALJ A;  2ANH A;  1ELX A;  3NKO A;  5L0E A;  1B8J A;  4LRA A;  3MK1 A;  4ZGA A;  1O99 A;  2IUC A;  3T00 A;  4NWX A;  5GOV A;  1ALK A;  3WAX A;  4LRB A;  2GA3 A;  3TX0 A;  1URA A;  1AJD A;  1O98 A;  5L0B A;  2W5X A;  4LRC A;  5K4P A;  5AJ9 A;  3Q3Q A;  4LRE A;  1ZED A;  5EGE A;  3M7V A;  4CXU A;  4LR2 A;  3NKN A;  4UPL A;  1ZEB A;  3WAV A;  2QZU A;  1HDH A;  5KXA A;  4B56 A;  3OT9 A;  1KHN A;  1EW9 A;  3E2D A;  3UN5 A;  3DPC A;  3M8W A;  1E2S P;  1AUK A;  1EQJ A;  4GTW A;  1ANJ A;  4KAV A;  4QAX A;  1ANI A;  3DYC A;  4LR8 A;  3M8Z A;  3NKR A;  1Y7A A;  3M8Y A;  1FSU A;  2W5V A;  1Y6V A;  1E33 P;  2W5R A;  1EI6 A;  5INH A;  1ED9 A;  4ZG7 A;  3UNY A;  1EJJ A;  5LRM A;  4FDJ A;  1EW8 A;  1KH5 A;  3BDG B;  1N2L A;  3CMR A;  3BDF A;  2W5Q A;  3B5Q A;  2W8S A;  1E1Z P;  3SZY A;  4FDI A;  4LRF A;  1ED8 A;  3WBH A;  3BDH A;  2IFY A;  5LRN A;  3T01 A;  3MK2 A;  4CXS A;  3UO0 A;  5LIA A;  3IGZ B;  1URB A;  5DLT A;  4ZG9 A;  1KHL A;  3NKQ A;  2RH6 A;  4GTZ A;  4LR9 A;  2GSO A;  2D1G A;  2W5W A;  1SHQ A;  1HQA A;  4KM4 A;  3WAY A;  1HJK A;  3IGY B;  1AJA A;  2XR9 A;  4KJD A;  1EW2 A;  5L0K A;  4MY4 A;  1AJB A;  4UPK A;  1KHJ A;  4LRD A;  5EGH A;  5GRR A;  1KH4 A;  4NWJ A;  1AJC A;  4LR7 A;  3TG0 A;  1KHK A;  2W8D A;  2GSU A;  4UPI A;  2X98 A;  3BDG A;  3A52 A;  4UPH A;  2GSN A; 
#chains in the Genus database with same CATH homology
 3KD8 A;  2W5S A;  2GLQ A;  4UOO A;  4N7T A;  2W5T A;  2IUC B;  1N2K A;  3MK0 A;  4KAY A;  5HRT A;  4MHX A;  4MIV A;  1K7H A;  4CXK A;  1ALI A;  2G9Y A;  4KJG A;  1KH9 A;  4LQY A;  1P49 A;  4UOP A;  3T02 A;  4CYR A;  3UN2 A;  4GTX A;  5DLW A;  3UN3 A;  1SHN A;  5TJ3 A;  4TN0 A;  1ZEF A;  4CYS A;  2VQR A;  3ED4 A;  1ELZ A;  2XRG A;  4UOR A;  4YR1 A;  5DLV A;  1E3C P;  3TWZ A;  1ELY A;  3NKP A;  5LQQ A;  4GTY A;  3IDD A;  5IJQ A;  3SZZ A;  5C66 A;  3NKM A;  5IJS A;  1KH7 A;  2ZKT A;  3LXQ A;  3WAW A;  1ALH A;  3NVL A;  4ZG6 A;  1ALJ A;  2ANH A;  1ELX A;  3NKO A;  5L0E A;  1B8J A;  4LRA A;  3MK1 A;  4ZGA A;  1O99 A;  2IUC A;  3T00 A;  4NWX A;  5GOV A;  1ALK A;  3WAX A;  4LRB A;  2GA3 A;  3TX0 A;  1URA A;  1AJD A;  1O98 A;  5L0B A;  2W5X A;  4LRC A;  5K4P A;  5AJ9 A;  3Q3Q A;  4LRE A;  1ZED A;  5EGE A;  3M7V A;  4CXU A;  4LR2 A;  3NKN A;  4UPL A;  1ZEB A;  3WAV A;  2QZU A;  1HDH A;  5KXA A;  4B56 A;  3OT9 A;  1KHN A;  1EW9 A;  3E2D A;  3UN5 A;  3DPC A;  3M8W A;  1E2S P;  1AUK A;  1EQJ A;  4GTW A;  1ANJ A;  4KAV A;  4QAX A;  1ANI A;  3DYC A;  4LR8 A;  3M8Z A;  3NKR A;  1Y7A A;  3M8Y A;  1FSU A;  2W5V A;  1Y6V A;  1E33 P;  2W5R A;  1EI6 A;  5INH A;  1ED9 A;  4ZG7 A;  3UNY A;  1EJJ A;  5LRM A;  4FDJ A;  1EW8 A;  1KH5 A;  3BDG B;  1N2L A;  3CMR A;  3BDF A;  2W5Q A;  3B5Q A;  2W8S A;  1E1Z P;  3SZY A;  4FDI A;  4LRF A;  1ED8 A;  3WBH A;  3BDH A;  2IFY A;  5LRN A;  3T01 A;  3MK2 A;  4CXS A;  3UO0 A;  5LIA A;  3IGZ B;  1URB A;  5DLT A;  4ZG9 A;  1KHL A;  3NKQ A;  2RH6 A;  4GTZ A;  4LR9 A;  2GSO A;  2D1G A;  2W5W A;  1SHQ A;  1HQA A;  4KM4 A;  3WAY A;  1HJK A;  3IGY B;  1AJA A;  2XR9 A;  4KJD A;  1EW2 A;  5L0K A;  4MY4 A;  1AJB A;  4UPK A;  1KHJ A;  4LRD A;  5EGH A;  5GRR A;  1KH4 A;  4NWJ A;  1AJC A;  4LR7 A;  3TG0 A;  1KHK A;  2W8D A;  2GSU A;  4UPI A;  2X98 A;  3BDG A;  3A52 A;  4UPH A;  2GSN A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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