1Y62A

A 2.4 crystal structure of conkunitzin-s1, a novel kunitz-fold cone snail neurotoxin.
Total Genus 9
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
9
sequence length
56
structure length
56
Chain Sequence
RPSLCDLPADSGSGTKAEKRIYYNSARKQCLRFDYTGQGGNENNFRRTYDCQRTCL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure of conkunitzin-S1, a neurotoxin and Kunitz-fold disulfide variant from cone snail.
pubmed doi rcsb
molecule tags Toxin
molecule keywords Conkunitzin-S1
total genus 9
structure length 56
sequence length 56
chains with identical sequence B, C, D, E, F
ec nomenclature
pdb deposition date 2004-12-03

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00014 Kunitz_BPTI Kunitz/Bovine pancreatic trypsin inhibitor domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
4.10.410.10 Few Secondary Structures Irregular Factor Xa Inhibitor Pancreatic trypsin inhibitor Kunitz domain 1y62A00
3BYBA 3TGII 4BQDA 1CBWD 1KTHA 3BTWI 4DG4C 1P2OB 1BRBI 1YKTB 3BTGI 3BTEI 3FP8I 1UUBA 4WXVC 1FAKI 1OA65 1D0DA 3AUIA 4BNRI 3P92E 1TCPA 1LD5A 6PTIA 2ZJXA 1CA0D 1YLDB 1UUAA 1YLCB 3LDIA 1JV9A 1BPIA 1AAPA 1SHPA 2FTMB 3P95E 1ADZA 3TGKI 3WNYA 1DENA 2M99A 3FP6I 3UOUB 5C67C 3L3TE 3AUEA 7PTIA 4DTGK 2TPII 2CA7A 2R9PE 4NTYB 1MTND 1EJMB 1D0DB 1T8NB 4NTXB 1F5RI 4Y0YI 1P2MB 3OFWA 5JB7A 1BF0A 2JOTA 5PTIA 3BTDI 1ZJDB 4NTWB 1BTHP 2LFKA 1TOCR 2HEXA 2FI3I 1KUNA 3CI7A 4Y0ZI 3TGJI 1G6XA 1TPAI 3BTQI 1B0CA 3AUCA 2KNTA 1P2NB 1EAWB 2KAII 3AUGA 1BTIA 2LFLA 3UIRC 1YC0I 1BPTA 1P2JI 1AALA 3BTMI 1NAGA 3LDJA 4U30W 3AUDA 1T7CB 4Y11I 1Y62A 4PTIA 1OA55 3AUBA 3BTFI 1DEMA 1FY8I 1TFXC 3BTKI 2ZVXA 3OTJI 5JB4A 1TAWB 1TAPA 4WWYC 1QLQA 1T8MB 1PITA 2J6DA 1BRCI 1P2KI 2FI4I 2UUYB 3FP7J 3TPII 8PTIA 2FI5I 1P2QB 2KCRA 2W8XA 3U1JE 2DDJA 1BHCA 4ISLB 2TGPI 2UUXA 5JB6A 4Y10I 4ISOB 1K6UA 1ZR0B 3T62D 1T8OB 1KIGI 3GYMI 3M7QB 1KNTA 1IRHA 3AUHA 1BIKA 1LD6A 3D65I 4U32X 4TPII 5JB5A 9PTIA 2DDIA 1JV8A 2RA3C 4ISNB 1BZXI 1T8LB 2FTLI 1DTXA 2ODYE 3BTTI 3LDMA 1JC6A 1BZ5A 2PTCI 1CO7I 1BUNB 3L33E 1F7ZI 3BTHI 2IJOI 1P2II 1FANA 1DTKA 4BD9B 2M01A
chains in the Genus database with same CATH superfamily
3BYBA 3TGII 4BQDA 1CBWD 1KTHA 3BTWI 4DG4C 1P2OB 1BRBI 1YKTB 3BTGI 3BTEI 3FP8I 1UUBA 4WXVC 1FAKI 1OA65 1D0DA 3AUIA 4BNRI 3P92E 1TCPA 1LD5A 6PTIA 2ZJXA 1CA0D 1YLDB 1UUAA 1YLCB 3LDIA 1JV9A 1BPIA 1AAPA 1SHPA 2FTMB 3P95E 1ADZA 3TGKI 3WNYA 1DENA 2M99A 3FP6I 3UOUB 5C67C 3L3TE 3AUEA 7PTIA 4DTGK 2TPII 2CA7A 2R9PE 4NTYB 1MTND 1EJMB 1D0DB 1T8NB 4NTXB 1F5RI 4Y0YI 1P2MB 3OFWA 5JB7A 1BF0A 2JOTA 5PTIA 3BTDI 1ZJDB 4NTWB 1BTHP 2LFKA 1TOCR 2HEXA 2FI3I 1KUNA 3CI7A 4Y0ZI 3TGJI 1G6XA 1TPAI 3BTQI 1B0CA 3AUCA 2KNTA 1P2NB 1EAWB 2KAII 3AUGA 1BTIA 2LFLA 3UIRC 1YC0I 1BPTA 1P2JI 1AALA 3BTMI 1NAGA 3LDJA 4U30W 3AUDA 1T7CB 4Y11I 1Y62A 4PTIA 1OA55 3AUBA 3BTFI 1DEMA 1FY8I 1TFXC 3BTKI 2ZVXA 3OTJI 5JB4A 1TAWB 1TAPA 4WWYC 1QLQA 1T8MB 1PITA 2J6DA 1BRCI 1P2KI 2FI4I 2UUYB 3FP7J 3TPII 8PTIA 2FI5I 1P2QB 2KCRA 2W8XA 3U1JE 2DDJA 1BHCA 4ISLB 2TGPI 2UUXA 5JB6A 4Y10I 4ISOB 1K6UA 1ZR0B 3T62D 1T8OB 1KIGI 3GYMI 3M7QB 1KNTA 1IRHA 3AUHA 1BIKA 1LD6A 3D65I 4U32X 4TPII 5JB5A 9PTIA 2DDIA 1JV8A 2RA3C 4ISNB 1BZXI 1T8LB 2FTLI 1DTXA 2ODYE 3BTTI 3LDMA 1JC6A 1BZ5A 2PTCI 1CO7I 1BUNB 3L33E 1F7ZI 3BTHI 2IJOI 1P2II 1FANA 1DTKA 4BD9B 2M01A
chains in the Genus database with same CATH topology
3BYBA 3TGII 4BQDA 1CBWD 1KTHA 3BTWI 4DG4C 1P2OB 1BRBI 1YKTB 3BTGI 3BTEI 3FP8I 1UUBA 4WXVC 1FAKI 1OA65 1D0DA 3AUIA 4BNRI 3P92E 1TCPA 1LD5A 6PTIA 2ZJXA 1CA0D 1YLDB 1UUAA 1YLCB 3LDIA 1JV9A 1BPIA 1AAPA 1SHPA 2FTMB 3P95E 1ADZA 3TGKI 3WNYA 1DENA 2M99A 3FP6I 3UOUB 5C67C 3L3TE 3AUEA 7PTIA 4DTGK 2TPII 2CA7A 2R9PE 4NTYB 1MTND 1EJMB 1D0DB 1T8NB 4NTXB 1F5RI 4Y0YI 1P2MB 3OFWA 5JB7A 1BF0A 2JOTA 5PTIA 3BTDI 1ZJDB 4NTWB 1BTHP 2LFKA 1TOCR 2HEXA 2FI3I 1KUNA 3CI7A 4Y0ZI 3TGJI 1G6XA 1TPAI 3BTQI 1B0CA 3AUCA 2KNTA 1P2NB 1EAWB 2KAII 3AUGA 1BTIA 2LFLA 3UIRC 1YC0I 1BPTA 1P2JI 1AALA 3BTMI 1NAGA 3LDJA 4U30W 3AUDA 1T7CB 4Y11I 1Y62A 4PTIA 1OA55 3AUBA 3BTFI 1DEMA 1FY8I 1TFXC 3BTKI 2ZVXA 3OTJI 5JB4A 1TAWB 1TAPA 4WWYC 1QLQA 1T8MB 1PITA 2J6DA 1BRCI 1P2KI 2FI4I 2UUYB 3FP7J 3TPII 8PTIA 2FI5I 1P2QB 2KCRA 2W8XA 3U1JE 2DDJA 1BHCA 4ISLB 2TGPI 2UUXA 5JB6A 4Y10I 4ISOB 1K6UA 1ZR0B 3T62D 1T8OB 1KIGI 3GYMI 3M7QB 1KNTA 1IRHA 3AUHA 1BIKA 1LD6A 3D65I 4U32X 4TPII 5JB5A 9PTIA 2DDIA 1JV8A 2RA3C 4ISNB 1BZXI 1T8LB 2FTLI 1DTXA 2ODYE 3BTTI 3LDMA 1JC6A 1BZ5A 2PTCI 1CO7I 1BUNB 3L33E 1F7ZI 3BTHI 2IJOI 1P2II 1FANA 1DTKA 4BD9B 2M01A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3BYB A;  3TGI I;  4BQD A;  1CBW D;  1KTH A;  3BTW I;  4DG4 C;  1P2O B;  1BRB I;  1YKT B;  3BTG I;  3BTE I;  3FP8 I;  1UUB A;  4WXV C;  1FAK I;  1OA6 5;  1D0D A;  3AUI A;  4BNR I;  3P92 E;  1TCP A;  1LD5 A;  6PTI A;  2ZJX A;  1CA0 D;  1YLD B;  1UUA A;  1YLC B;  3LDI A;  1JV9 A;  1BPI A;  1AAP A;  1SHP A;  2FTM B;  3P95 E;  1ADZ A;  3TGK I;  3WNY A;  1DEN A;  2M99 A;  3FP6 I;  3UOU B;  5C67 C;  3L3T E;  3AUE A;  7PTI A;  4DTG K;  2TPI I;  2CA7 A;  2R9P E;  4NTY B;  1MTN D;  1EJM B;  1D0D B;  1T8N B;  4NTX B;  1F5R I;  4Y0Y I;  1P2M B;  3OFW A;  5JB7 A;  1BF0 A;  2JOT A;  5PTI A;  3BTD I;  1ZJD B;  4NTW B;  1BTH P;  2LFK A;  1TOC R;  2HEX A;  2FI3 I;  1KUN A;  3CI7 A;  4Y0Z I;  3TGJ I;  1G6X A;  1TPA I;  3BTQ I;  1B0C A;  3AUC A;  2KNT A;  1P2N B;  1EAW B;  2KAI I;  3AUG A;  1BTI A;  2LFL A;  3UIR C;  1YC0 I;  1BPT A;  1P2J I;  1AAL A;  3BTM I;  1NAG A;  3LDJ A;  4U30 W;  3AUD A;  1T7C B;  4Y11 I;  1Y62 A;  4PTI A;  1OA5 5;  3AUB A;  3BTF I;  1DEM A;  1FY8 I;  1TFX C;  3BTK I;  2ZVX A;  3OTJ I;  5JB4 A;  1TAW B;  1TAP A;  4WWY C;  1QLQ A;  1T8M B;  1PIT A;  2J6D A;  1BRC I;  1P2K I;  2FI4 I;  2UUY B;  3FP7 J;  3TPI I;  8PTI A;  2FI5 I;  1P2Q B;  2KCR A;  2W8X A;  3U1J E;  2DDJ A;  1BHC A;  4ISL B;  2TGP I;  2UUX A;  5JB6 A;  4Y10 I;  4ISO B;  1K6U A;  1ZR0 B;  3T62 D;  1T8O B;  1KIG I;  3GYM I;  3M7Q B;  1KNT A;  1IRH A;  3AUH A;  1BIK A;  1LD6 A;  3D65 I;  4U32 X;  4TPI I;  5JB5 A;  9PTI A;  2DDI A;  1JV8 A;  2RA3 C;  4ISN B;  1BZX I;  1T8L B;  2FTL I;  1DTX A;  2ODY E;  3BTT I;  3LDM A;  1JC6 A;  1BZ5 A;  2PTC I;  1CO7 I;  1BUN B;  3L33 E;  1F7Z I;  3BTH I;  2IJO I;  1P2I I;  1FAN A;  1DTK A;  4BD9 B;  2M01 A; 
#chains in the Genus database with same CATH topology
 3BYB A;  3TGI I;  4BQD A;  1CBW D;  1KTH A;  3BTW I;  4DG4 C;  1P2O B;  1BRB I;  1YKT B;  3BTG I;  3BTE I;  3FP8 I;  1UUB A;  4WXV C;  1FAK I;  1OA6 5;  1D0D A;  3AUI A;  4BNR I;  3P92 E;  1TCP A;  1LD5 A;  6PTI A;  2ZJX A;  1CA0 D;  1YLD B;  1UUA A;  1YLC B;  3LDI A;  1JV9 A;  1BPI A;  1AAP A;  1SHP A;  2FTM B;  3P95 E;  1ADZ A;  3TGK I;  3WNY A;  1DEN A;  2M99 A;  3FP6 I;  3UOU B;  5C67 C;  3L3T E;  3AUE A;  7PTI A;  4DTG K;  2TPI I;  2CA7 A;  2R9P E;  4NTY B;  1MTN D;  1EJM B;  1D0D B;  1T8N B;  4NTX B;  1F5R I;  4Y0Y I;  1P2M B;  3OFW A;  5JB7 A;  1BF0 A;  2JOT A;  5PTI A;  3BTD I;  1ZJD B;  4NTW B;  1BTH P;  2LFK A;  1TOC R;  2HEX A;  2FI3 I;  1KUN A;  3CI7 A;  4Y0Z I;  3TGJ I;  1G6X A;  1TPA I;  3BTQ I;  1B0C A;  3AUC A;  2KNT A;  1P2N B;  1EAW B;  2KAI I;  3AUG A;  1BTI A;  2LFL A;  3UIR C;  1YC0 I;  1BPT A;  1P2J I;  1AAL A;  3BTM I;  1NAG A;  3LDJ A;  4U30 W;  3AUD A;  1T7C B;  4Y11 I;  1Y62 A;  4PTI A;  1OA5 5;  3AUB A;  3BTF I;  1DEM A;  1FY8 I;  1TFX C;  3BTK I;  2ZVX A;  3OTJ I;  5JB4 A;  1TAW B;  1TAP A;  4WWY C;  1QLQ A;  1T8M B;  1PIT A;  2J6D A;  1BRC I;  1P2K I;  2FI4 I;  2UUY B;  3FP7 J;  3TPI I;  8PTI A;  2FI5 I;  1P2Q B;  2KCR A;  2W8X A;  3U1J E;  2DDJ A;  1BHC A;  4ISL B;  2TGP I;  2UUX A;  5JB6 A;  4Y10 I;  4ISO B;  1K6U A;  1ZR0 B;  3T62 D;  1T8O B;  1KIG I;  3GYM I;  3M7Q B;  1KNT A;  1IRH A;  3AUH A;  1BIK A;  1LD6 A;  3D65 I;  4U32 X;  4TPI I;  5JB5 A;  9PTI A;  2DDI A;  1JV8 A;  2RA3 C;  4ISN B;  1BZX I;  1T8L B;  2FTL I;  1DTX A;  2ODY E;  3BTT I;  3LDM A;  1JC6 A;  1BZ5 A;  2PTC I;  1CO7 I;  1BUN B;  3L33 E;  1F7Z I;  3BTH I;  2IJO I;  1P2I I;  1FAN A;  1DTK A;  4BD9 B;  2M01 A; 
#chains in the Genus database with same CATH homology
 3BYB A;  3TGI I;  4BQD A;  1CBW D;  1KTH A;  3BTW I;  4DG4 C;  1P2O B;  1BRB I;  1YKT B;  3BTG I;  3BTE I;  3FP8 I;  1UUB A;  4WXV C;  1FAK I;  1OA6 5;  1D0D A;  3AUI A;  4BNR I;  3P92 E;  1TCP A;  1LD5 A;  6PTI A;  2ZJX A;  1CA0 D;  1YLD B;  1UUA A;  1YLC B;  3LDI A;  1JV9 A;  1BPI A;  1AAP A;  1SHP A;  2FTM B;  3P95 E;  1ADZ A;  3TGK I;  3WNY A;  1DEN A;  2M99 A;  3FP6 I;  3UOU B;  5C67 C;  3L3T E;  3AUE A;  7PTI A;  4DTG K;  2TPI I;  2CA7 A;  2R9P E;  4NTY B;  1MTN D;  1EJM B;  1D0D B;  1T8N B;  4NTX B;  1F5R I;  4Y0Y I;  1P2M B;  3OFW A;  5JB7 A;  1BF0 A;  2JOT A;  5PTI A;  3BTD I;  1ZJD B;  4NTW B;  1BTH P;  2LFK A;  1TOC R;  2HEX A;  2FI3 I;  1KUN A;  3CI7 A;  4Y0Z I;  3TGJ I;  1G6X A;  1TPA I;  3BTQ I;  1B0C A;  3AUC A;  2KNT A;  1P2N B;  1EAW B;  2KAI I;  3AUG A;  1BTI A;  2LFL A;  3UIR C;  1YC0 I;  1BPT A;  1P2J I;  1AAL A;  3BTM I;  1NAG A;  3LDJ A;  4U30 W;  3AUD A;  1T7C B;  4Y11 I;  1Y62 A;  4PTI A;  1OA5 5;  3AUB A;  3BTF I;  1DEM A;  1FY8 I;  1TFX C;  3BTK I;  2ZVX A;  3OTJ I;  5JB4 A;  1TAW B;  1TAP A;  4WWY C;  1QLQ A;  1T8M B;  1PIT A;  2J6D A;  1BRC I;  1P2K I;  2FI4 I;  2UUY B;  3FP7 J;  3TPI I;  8PTI A;  2FI5 I;  1P2Q B;  2KCR A;  2W8X A;  3U1J E;  2DDJ A;  1BHC A;  4ISL B;  2TGP I;  2UUX A;  5JB6 A;  4Y10 I;  4ISO B;  1K6U A;  1ZR0 B;  3T62 D;  1T8O B;  1KIG I;  3GYM I;  3M7Q B;  1KNT A;  1IRH A;  3AUH A;  1BIK A;  1LD6 A;  3D65 I;  4U32 X;  4TPI I;  5JB5 A;  9PTI A;  2DDI A;  1JV8 A;  2RA3 C;  4ISN B;  1BZX I;  1T8L B;  2FTL I;  1DTX A;  2ODY E;  3BTT I;  3LDM A;  1JC6 A;  1BZ5 A;  2PTC I;  1CO7 I;  1BUN B;  3L33 E;  1F7Z I;  3BTH I;  2IJO I;  1P2I I;  1FAN A;  1DTK A;  4BD9 B;  2M01 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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