The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.
Total Genus |
7
|
sequence length |
42
|
structure length |
42
|
Chain Sequence |
DAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIA
|
The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.
After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.
| publication title |
The alpha-to-beta Conformational Transition of Alzheimer's Abeta-(1-42) Peptide in Aqueous Media is Reversible: A Step by Step Conformational Analysis Suggests the Location of beta Conformation Seeding
pubmed doi rcsb |
| molecule tags |
Protein binding
|
| molecule keywords |
Alzheimer's disease amyloid
|
| total genus |
7
|
| structure length |
42
|
| sequence length |
42
|
| ec nomenclature | |
| pdb deposition date | 2005-03-02 |
| chain | Pfam Accession Code | Pfam Family Identifier | Pfam Description |
|---|---|---|---|
| A | PF03494 | Beta-APP | Beta-amyloid peptide (beta-APP) |
Image from the rcsb pdb (www.rcsb.org)
cath code
| Class | Architecture | Topology | Homology | Domain |
|---|---|---|---|---|---|
| Few Secondary Structures | Irregular | Amyloid A4 | Amyloidogenic glycoprotein, amyloid-beta peptide |
#chains in the Genus database with same CATH superfamily 1IYT A; 1Z0Q A; 1BA4 A; 1AML A; #chains in the Genus database with same CATH topology 1IYT A; 1Z0Q A; 1BA4 A; 1AML A; #chains in the Genus database with same CATH homology 1IYT A; 1Z0Q A; 1BA4 A; 1AML A;
#similar chains in the Genus database (?% sequence similarity) ...loading similar chains, please wait... #similar chains, but unknotted ...loading similar chains, please wait... #similar chains in the pdb database (?% sequence similarity) ...loading similar chains, please wait...
