1Z3SA

Angiopoietin-2 receptor binding domain
Total Genus 61
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
61
sequence length
216
structure length
216
Chain Sequence
EFRDCAEVFKSGHTTNGIYTLTFPNSTEEIKAYCDMEAGGGGWTIIQRREDGSVDFQRTWKEYKVGFGNPSGEYWLGNEFVSQLTNQQRYVLKIHLKDWEGNEAYSLYEHFYLSSEELNYRIHLKGLTGTAGKISSISQPGNDFSTKDGDNDKCICKCSQMLTGGWWFDACGPSNLNGMYYPQRQNTNKFNGIKWYYWKGSGYSLKATTMMIRPAD
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structure of the angiopoietin-2 receptor binding domain and identification of surfaces involved in Tie2 recognition.
pubmed doi rcsb
molecule tags Signaling protein
source organism Homo sapiens
molecule keywords Angiopoietin-2
total genus 61
structure length 216
sequence length 216
chains with identical sequence B
ec nomenclature
pdb deposition date 2005-03-14
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.215.10 Alpha Beta Alpha-Beta Complex Gamma Fibrinogen; Chain A, domain 1 Gamma Fibrinogen, chain A, domain 1 1z3sA01
4.10.530.10 Few Secondary Structures Irregular Gamma-fibrinogen Carboxyl Terminal Fragment; domain 2 Gamma-fibrinogen Carboxyl Terminal Fragment, domain 2 1z3sA02
2OYIC 2J3GA 1LTJB 2J3FD 1Z3SA 1FZAC 2HODC 1FZFB 2J0YA 2J2PA 1LTJC 1FZDA 3BVHC 1LT9B 2JHHC 3HUSB 1FZBB 1FZFC 2HPCB 2J60A 1JC9A 2D39A 1LT9C 1N73B 2JHIF 2J3FA 3HUSC 1FZBC 2J61A 1RF1B 3GHGC 3H32B 1N73C 2FFDC 2HLOB 2XNXB 1RF1C 1FZEB 4R9JA 3E1IB 2WNPF 2Q9IB 4EPUA 4M7HA 2XNXC 1FZEC 3E1IC 4R9TA 2H43B 1FZCB 1RF0B 1FIDA 2J3UA 2Q9IC 2HPCC 1FIBA 2OYHB 1RE4B 2J61B 2H43C 1RF0C 1M1JB 2GY7A 2JHMF 1RE4C 3H32C 1LWUB 2J1GA 1FZGB 1M1JC 2HLOC 1N86B 1RE3B 4JZCA 3BVHB 2J3OA 3FIBA 2Z4EB 2J64A 1LWUC 2JHLF 1FZGC 4M7FA 2JHKF 1N86C 1RE3C 4JYOX 2FIBA 2J0HA 2Z4EC 1FZCC 4NYTA 2OYIB 2J0GA 2J5ZA 2OYHC 1FZAB 4ZFGA 1Z3UA 2HODB 2FFDB 1FICA
chains in the Genus database with same CATH superfamily
2OYIC 2J3GA 1LTJB 2J3FD 1Z3SA 1FZAC 2HODC 1FZFB 2J0YA 2J2PA 1LTJC 1FZDA 3BVHC 1LT9B 2JHHC 3HUSB 1FZBB 1FZFC 2HPCB 2J60A 3GHGB 1JC9A 2D39A 1LT9C 1N73B 2JHIF 2J3FA 3HUSC 1FZBC 2J61A 1RF1B 3GHGC 3H32B 1N73C 2FFDC 2HLOB 2XNXB 1RF1C 1FZEB 4R9JA 3E1IB 2WNPF 2Q9IB 4EPUA 4M7HA 2XNXC 1FZEC 3E1IC 4R9TA 2H43B 1FZCB 1RF0B 1FIDA 2J3UA 2Q9IC 2HPCC 1FIBA 2OYHB 1RE4B 2J61B 2H43C 1RF0C 1M1JB 2GY7A 2JHMF 1RE4C 3H32C 1LWUB 2J1GA 1FZGB 1M1JC 2HLOC 1N86B 1RE3B 4JZCA 3BVHB 2J3OA 3FIBA 2Z4EB 2J64A 1LWUC 2JHLF 1FZGC 4M7FA 2JHKF 1N86C 1RE3C 4JYOX 2FIBA 2J0HA 2Z4EC 1FZCC 4NYTA 2OYIB 2J0GA 2J5ZA 2OYHC 1FZAB 4ZFGA 1Z3UA 2HODB 2FFDB 1FICA
chains in the Genus database with same CATH topology
2OYIC 2J3GA 1LTJB 2J3FD 1Z3SA 1FZAC 2HODC 1FZFB 2J0YA 2J2PA 1LTJC 1FZDA 3BVHC 1LT9B 2JHHC 3HUSB 1FZBB 1FZFC 2HPCB 2J60A 1JC9A 2D39A 1LT9C 1N73B 2JHIF 2J3FA 3HUSC 1FZBC 2J61A 1RF1B 3GHGC 3H32B 1N73C 2FFDC 2HLOB 2XNXB 1RF1C 1FZEB 4R9JA 3E1IB 2WNPF 2Q9IB 4EPUA 4M7HA 2XNXC 1FZEC 3E1IC 4R9TA 2H43B 1FZCB 1RF0B 1FIDA 2J3UA 2Q9IC 2HPCC 1FIBA 2OYHB 1RE4B 2J61B 2H43C 1RF0C 1M1JB 2GY7A 2JHMF 1RE4C 3H32C 1LWUB 2J1GA 1FZGB 1M1JC 2HLOC 1N86B 1RE3B 4JZCA 3BVHB 2J3OA 3FIBA 2Z4EB 2J64A 1LWUC 2JHLF 1FZGC 4M7FA 2JHKF 1N86C 1RE3C 4JYOX 2FIBA 2J0HA 2Z4EC 1FZCC 4NYTA 2OYIB 2J0GA 2J5ZA 2OYHC 1FZAB 4ZFGA 1Z3UA 2HODB 2FFDB 1FICA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2OYI C;  2J3G A;  1LTJ B;  2J3F D;  1Z3S A;  1FZA C;  2HOD C;  1FZF B;  2J0Y A;  2J2P A;  1LTJ C;  1FZD A;  3BVH C;  1LT9 B;  2JHH C;  3HUS B;  1FZB B;  1FZF C;  2HPC B;  2J60 A;  1JC9 A;  2D39 A;  1LT9 C;  1N73 B;  2JHI F;  2J3F A;  3HUS C;  1FZB C;  2J61 A;  1RF1 B;  3GHG C;  3H32 B;  1N73 C;  2FFD C;  2HLO B;  2XNX B;  1RF1 C;  1FZE B;  4R9J A;  3E1I B;  2WNP F;  2Q9I B;  4EPU A;  4M7H A;  2XNX C;  1FZE C;  3E1I C;  4R9T A;  2H43 B;  1FZC B;  1RF0 B;  1FID A;  2J3U A;  2Q9I C;  2HPC C;  1FIB A;  2OYH B;  1RE4 B;  2J61 B;  2H43 C;  1RF0 C;  1M1J B;  2GY7 A;  2JHM F;  1RE4 C;  3H32 C;  1LWU B;  2J1G A;  1FZG B;  1M1J C;  2HLO C;  1N86 B;  1RE3 B;  4JZC A;  3BVH B;  2J3O A;  3FIB A;  2Z4E B;  2J64 A;  1LWU C;  2JHL F;  1FZG C;  4M7F A;  2JHK F;  1N86 C;  1RE3 C;  4JYO X;  2FIB A;  2J0H A;  2Z4E C;  1FZC C;  4NYT A;  2OYI B;  2J0G A;  2J5Z A;  2OYH C;  1FZA B;  4ZFG A;  1Z3U A;  2HOD B;  2FFD B;  1FIC A; 
#chains in the Genus database with same CATH topology
 2OYI C;  2J3G A;  1LTJ B;  2J3F D;  1Z3S A;  1FZA C;  2HOD C;  1FZF B;  2J0Y A;  2J2P A;  1LTJ C;  1FZD A;  3BVH C;  1LT9 B;  2JHH C;  3HUS B;  1FZB B;  1FZF C;  2HPC B;  2J60 A;  3GHG B;  1JC9 A;  2D39 A;  1LT9 C;  1N73 B;  2JHI F;  2J3F A;  3HUS C;  1FZB C;  2J61 A;  1RF1 B;  3GHG C;  3H32 B;  1N73 C;  2FFD C;  2HLO B;  2XNX B;  1RF1 C;  1FZE B;  4R9J A;  3E1I B;  2WNP F;  2Q9I B;  4EPU A;  4M7H A;  2XNX C;  1FZE C;  3E1I C;  4R9T A;  2H43 B;  1FZC B;  1RF0 B;  1FID A;  2J3U A;  2Q9I C;  2HPC C;  1FIB A;  2OYH B;  1RE4 B;  2J61 B;  2H43 C;  1RF0 C;  1M1J B;  2GY7 A;  2JHM F;  1RE4 C;  3H32 C;  1LWU B;  2J1G A;  1FZG B;  1M1J C;  2HLO C;  1N86 B;  1RE3 B;  4JZC A;  3BVH B;  2J3O A;  3FIB A;  2Z4E B;  2J64 A;  1LWU C;  2JHL F;  1FZG C;  4M7F A;  2JHK F;  1N86 C;  1RE3 C;  4JYO X;  2FIB A;  2J0H A;  2Z4E C;  1FZC C;  4NYT A;  2OYI B;  2J0G A;  2J5Z A;  2OYH C;  1FZA B;  4ZFG A;  1Z3U A;  2HOD B;  2FFD B;  1FIC A; 
#chains in the Genus database with same CATH homology
 2OYI C;  2J3G A;  1LTJ B;  2J3F D;  1Z3S A;  1FZA C;  2HOD C;  1FZF B;  2J0Y A;  2J2P A;  1LTJ C;  1FZD A;  3BVH C;  1LT9 B;  2JHH C;  3HUS B;  1FZB B;  1FZF C;  2HPC B;  2J60 A;  1JC9 A;  2D39 A;  1LT9 C;  1N73 B;  2JHI F;  2J3F A;  3HUS C;  1FZB C;  2J61 A;  1RF1 B;  3GHG C;  3H32 B;  1N73 C;  2FFD C;  2HLO B;  2XNX B;  1RF1 C;  1FZE B;  4R9J A;  3E1I B;  2WNP F;  2Q9I B;  4EPU A;  4M7H A;  2XNX C;  1FZE C;  3E1I C;  4R9T A;  2H43 B;  1FZC B;  1RF0 B;  1FID A;  2J3U A;  2Q9I C;  2HPC C;  1FIB A;  2OYH B;  1RE4 B;  2J61 B;  2H43 C;  1RF0 C;  1M1J B;  2GY7 A;  2JHM F;  1RE4 C;  3H32 C;  1LWU B;  2J1G A;  1FZG B;  1M1J C;  2HLO C;  1N86 B;  1RE3 B;  4JZC A;  3BVH B;  2J3O A;  3FIB A;  2Z4E B;  2J64 A;  1LWU C;  2JHL F;  1FZG C;  4M7F A;  2JHK F;  1N86 C;  1RE3 C;  4JYO X;  2FIB A;  2J0H A;  2Z4E C;  1FZC C;  4NYT A;  2OYI B;  2J0G A;  2J5Z A;  2OYH C;  1FZA B;  4ZFG A;  1Z3U A;  2HOD B;  2FFD B;  1FIC A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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