1ZEBA

X-ray structure of alkaline phosphatase from human placenta in complex with 5'-amp
Total Genus 173
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
173
Knots found
sequence length
480
structure length
479
Chain Sequence
b'IIPVEEENPDFWNREAAEALGAAKKLQPAQTAAKNLIIFLGDGMGVSTVTAARILKGQKKDKLGPEIPLAMDRFPYVALSKTYNVDKHVPDGATATAYLCGVKGNFQTIGLSAAARFNQCNTTRGNEVISVMNRAKKAGKSVGVVTTTRVQHASPAGTYAHTVNRNWYSDADVPASARQEGCQDIATQLISNMDIDVILGGGRKYMFRMGTPDPEYPDDYSQGGTRLDGKNLVQEWLAKRQGARYVWNRTELMQASLDPSVTHLMGLFEPGDMKYEIHRDSTLDPSLMEMTEAALRLLSRNPRGFFLFVEGGRIDHGHHESRAYRALTETIMFDDAIERAGQLTSEEDTLSLVTADHSHVFSFGGYPLRGSSIFGLAPGKARDRKAYTVLLYGNGPGYVLKDGARPDVTESESGSPEYRQQSAVPLDEETHAGEDVAVFARGPQAHLVHGVQEQTFIAHVMAFAACLEPYTACDLAPPA'
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule keywords Alkaline phosphatase
publication title Structural Studies of Human Placental Alkaline Phosphatase in Complex with Functional Ligands.
pubmed doi rcsb
molecule tags Hydrolase
total genus 173
structure length 479
sequence length 480
other databases KnotProt 2.0: S +31
ec nomenclature ec 3.1.3.1: Alkaline phosphatase.
pdb deposition date 2005-04-18

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00245 Alk_phosphatase Alkaline phosphatase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.720.10 Alpha Beta 3-Layer(aba) Sandwich Alkaline Phosphatase, subunit A Alkaline Phosphatase, subunit A 1zebA00
1FSUA 4GTYA 2VQRA 4LR2A 3A52A 2ANHA 3IDDA 2GLQA 3BDFA 1KHLA 3T00A 4QAXA 4LR9A 3UNYA 1KH4A 2XR9A 4TN0A 3WAXA 4ZG7A 1ALIA 1EW2A 4UPIA 1O98A 1SHNA 3NKOA 5IJQA 4LQYA 3IGYB 1AJAA 3B5QA 4LRAA 3UN2A 3M8YA 4UPHA 3WBHA 3TG0A 4ZG6A 5HRTA 5L0BA 1ANJA 1N2KA 5KXAA 4UPLA 2W5VA 1E3CP 5LRNA 1EJJA 3WAWA 4N7TA 4GTXA 1E2SP 3NKNA 2X98A 4NWXA 1AJBA 1KH7A 1AJDA 2D1GA 3DPCA 3BDHA 4LRFA 3M7VA 2W5XA 4KJGA 4ZGAA 1AJCA 2W8SA 1EW9A 1KHJA 3IGZB 4FDJA 5L0KA 4UPKA 1ELYA 2QZUA 5LRMA 4MIVA 1ALJA 1E1ZP 1EI6A 3NKRA 4LR7A 3SZYA 1URBA 3MK0A 4UOPA 4LRCA 5DLTA 4KAVA 2GSUA 2RH6A 3BDGB 4LRDA 2IUCA 2XRGA 4CYRA 1ED8A 4UOOA 2GSOA 1EQJA 4CXUA 3WAYA 2GSNA 2W5QA 2ZKTA 3NVLA 1ANIA 3TWZA 1ALHA 3M8WA 1KH5A 2W5RA 1E33P 1O99A 2W5TA 3NKPA 1HDHA 5LIAA 5INHA 1AUKA 3LXQA 3CMRA 1ELXA 2W5SA 3MK2A 1SHQA 1ALKA 3MK1A 4B56A 1ED9A 4ZG9A 3UN5A 5IJSA 4KM4A 3OT9A 4UORA 3DYCA 2G9YA 4YR1A 1URAA 3E2DA 1ZEDA 5TJ3A 1HJKA 3NKMA 1HQAA 3UO0A 3KD8A 4NWJA 5GOVA 3WAVA 4CYSA 1EW8A 3ED4A 5DLWA 1KHKA 1KH9A 4LRBA 4GTWA 5C66A 3T02A 4KAYA 5L0EA 2W8DA 5DLVA 5EGEA 1Y6VA 1KHNA 2IUCB 3SZZA 3NKQA 4KJDA 4MHXA 1B8JA 4FDIA 4CXSA 1ELZA 4LR8A 3UN3A 1K7HA 2W5WA 4CXKA 2GA3A 4LREA 1P49A 3TX0A 5LQQA 5GRRA 3T01A 2IFYA 3Q3QA 5EGHA 5K4PA 1Y7AA 3M8ZA 3BDGA 1N2LA 4GTZA 1ZEBA 4MY4A 5AJ9A 1ZEFA
chains in the Genus database with same CATH superfamily
1FSUA 4GTYA 2VQRA 4LR2A 3A52A 2ANHA 3IDDA 2GLQA 3BDFA 1KHLA 3T00A 4QAXA 4LR9A 3UNYA 1KH4A 2XR9A 4TN0A 3WAXA 4ZG7A 1ALIA 1EW2A 4UPIA 1O98A 1SHNA 3NKOA 5IJQA 4LQYA 3IGYB 1AJAA 3B5QA 4LRAA 3UN2A 3M8YA 4UPHA 3WBHA 3TG0A 4ZG6A 5HRTA 5L0BA 1ANJA 1N2KA 5KXAA 4UPLA 2W5VA 1E3CP 5LRNA 1EJJA 3WAWA 4N7TA 4GTXA 1E2SP 3NKNA 2X98A 4NWXA 1AJBA 1KH7A 1AJDA 2D1GA 3DPCA 3BDHA 4LRFA 3M7VA 2W5XA 4KJGA 4ZGAA 1AJCA 2W8SA 1EW9A 1KHJA 3IGZB 4FDJA 5L0KA 4UPKA 1ELYA 2QZUA 5LRMA 4MIVA 1ALJA 1E1ZP 1EI6A 3NKRA 4LR7A 3SZYA 1URBA 3MK0A 4UOPA 4LRCA 5DLTA 4KAVA 2GSUA 2RH6A 3BDGB 4LRDA 2IUCA 2XRGA 4CYRA 1ED8A 4UOOA 2GSOA 1EQJA 4CXUA 3WAYA 2GSNA 2W5QA 2ZKTA 3NVLA 1ANIA 3TWZA 1ALHA 3M8WA 1KH5A 2W5RA 1E33P 1O99A 2W5TA 3NKPA 1HDHA 5LIAA 5INHA 1AUKA 3LXQA 3CMRA 1ELXA 2W5SA 3MK2A 1SHQA 1ALKA 3MK1A 4B56A 1ED9A 4ZG9A 3UN5A 5IJSA 4KM4A 3OT9A 4UORA 3DYCA 2G9YA 4YR1A 1URAA 3E2DA 1ZEDA 5TJ3A 1HJKA 3NKMA 1HQAA 3UO0A 3KD8A 4NWJA 5GOVA 3WAVA 4CYSA 1EW8A 3ED4A 5DLWA 1KHKA 1KH9A 4LRBA 4GTWA 5C66A 3T02A 4KAYA 5L0EA 2W8DA 5DLVA 5EGEA 1Y6VA 1KHNA 2IUCB 3SZZA 3NKQA 4KJDA 4MHXA 1B8JA 4FDIA 4CXSA 1ELZA 4LR8A 3UN3A 1K7HA 2W5WA 4CXKA 2GA3A 4LREA 1P49A 3TX0A 5LQQA 5GRRA 3T01A 2IFYA 3Q3QA 5EGHA 5K4PA 1Y7AA 3M8ZA 3BDGA 1N2LA 4GTZA 1ZEBA 4MY4A 5AJ9A 1ZEFA
chains in the Genus database with same CATH topology
1FSUA 4GTYA 2VQRA 4LR2A 3A52A 2ANHA 3IDDA 2GLQA 3BDFA 1KHLA 3T00A 4QAXA 4LR9A 3UNYA 1KH4A 2XR9A 4TN0A 3WAXA 4ZG7A 1ALIA 1EW2A 4UPIA 1O98A 1SHNA 3NKOA 5IJQA 4LQYA 3IGYB 1AJAA 3B5QA 4LRAA 3UN2A 3M8YA 4UPHA 3WBHA 3TG0A 4ZG6A 5HRTA 5L0BA 1ANJA 1N2KA 5KXAA 4UPLA 2W5VA 1E3CP 5LRNA 1EJJA 3WAWA 4N7TA 4GTXA 1E2SP 3NKNA 2X98A 4NWXA 1AJBA 1KH7A 1AJDA 2D1GA 3DPCA 3BDHA 4LRFA 3M7VA 2W5XA 4KJGA 4ZGAA 1AJCA 2W8SA 1EW9A 1KHJA 3IGZB 4FDJA 5L0KA 4UPKA 1ELYA 2QZUA 5LRMA 4MIVA 1ALJA 1E1ZP 1EI6A 3NKRA 4LR7A 3SZYA 1URBA 3MK0A 4UOPA 4LRCA 5DLTA 4KAVA 2GSUA 2RH6A 3BDGB 4LRDA 2IUCA 2XRGA 4CYRA 1ED8A 4UOOA 2GSOA 1EQJA 4CXUA 3WAYA 2GSNA 2W5QA 2ZKTA 3NVLA 1ANIA 3TWZA 1ALHA 3M8WA 1KH5A 2W5RA 1E33P 1O99A 2W5TA 3NKPA 1HDHA 5LIAA 5INHA 1AUKA 3LXQA 3CMRA 1ELXA 2W5SA 3MK2A 1SHQA 1ALKA 3MK1A 4B56A 1ED9A 4ZG9A 3UN5A 5IJSA 4KM4A 3OT9A 4UORA 3DYCA 2G9YA 4YR1A 1URAA 3E2DA 1ZEDA 5TJ3A 1HJKA 3NKMA 1HQAA 3UO0A 3KD8A 4NWJA 5GOVA 3WAVA 4CYSA 1EW8A 3ED4A 5DLWA 1KHKA 1KH9A 4LRBA 4GTWA 5C66A 3T02A 4KAYA 5L0EA 2W8DA 5DLVA 5EGEA 1Y6VA 1KHNA 2IUCB 3SZZA 3NKQA 4KJDA 4MHXA 1B8JA 4FDIA 4CXSA 1ELZA 4LR8A 3UN3A 1K7HA 2W5WA 4CXKA 2GA3A 4LREA 1P49A 3TX0A 5LQQA 5GRRA 3T01A 2IFYA 3Q3QA 5EGHA 5K4PA 1Y7AA 3M8ZA 3BDGA 1N2LA 4GTZA 1ZEBA 4MY4A 5AJ9A 1ZEFA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1FSU A;  4GTY A;  2VQR A;  4LR2 A;  3A52 A;  2ANH A;  3IDD A;  2GLQ A;  3BDF A;  1KHL A;  3T00 A;  4QAX A;  4LR9 A;  3UNY A;  1KH4 A;  2XR9 A;  4TN0 A;  3WAX A;  4ZG7 A;  1ALI A;  1EW2 A;  4UPI A;  1O98 A;  1SHN A;  3NKO A;  5IJQ A;  4LQY A;  3IGY B;  1AJA A;  3B5Q A;  4LRA A;  3UN2 A;  3M8Y A;  4UPH A;  3WBH A;  3TG0 A;  4ZG6 A;  5HRT A;  5L0B A;  1ANJ A;  1N2K A;  5KXA A;  4UPL A;  2W5V A;  1E3C P;  5LRN A;  1EJJ A;  3WAW A;  4N7T A;  4GTX A;  1E2S P;  3NKN A;  2X98 A;  4NWX A;  1AJB A;  1KH7 A;  1AJD A;  2D1G A;  3DPC A;  3BDH A;  4LRF A;  3M7V A;  2W5X A;  4KJG A;  4ZGA A;  1AJC A;  2W8S A;  1EW9 A;  1KHJ A;  3IGZ B;  4FDJ A;  5L0K A;  4UPK A;  1ELY A;  2QZU A;  5LRM A;  4MIV A;  1ALJ A;  1E1Z P;  1EI6 A;  3NKR A;  4LR7 A;  3SZY A;  1URB A;  3MK0 A;  4UOP A;  4LRC A;  5DLT A;  4KAV A;  2GSU A;  2RH6 A;  3BDG B;  4LRD A;  2IUC A;  2XRG A;  4CYR A;  1ED8 A;  4UOO A;  2GSO A;  1EQJ A;  4CXU A;  3WAY A;  2GSN A;  2W5Q A;  2ZKT A;  3NVL A;  1ANI A;  3TWZ A;  1ALH A;  3M8W A;  1KH5 A;  2W5R A;  1E33 P;  1O99 A;  2W5T A;  3NKP A;  1HDH A;  5LIA A;  5INH A;  1AUK A;  3LXQ A;  3CMR A;  1ELX A;  2W5S A;  3MK2 A;  1SHQ A;  1ALK A;  3MK1 A;  4B56 A;  1ED9 A;  4ZG9 A;  3UN5 A;  5IJS A;  4KM4 A;  3OT9 A;  4UOR A;  3DYC A;  2G9Y A;  4YR1 A;  1URA A;  3E2D A;  1ZED A;  5TJ3 A;  1HJK A;  3NKM A;  1HQA A;  3UO0 A;  3KD8 A;  4NWJ A;  5GOV A;  3WAV A;  4CYS A;  1EW8 A;  3ED4 A;  5DLW A;  1KHK A;  1KH9 A;  4LRB A;  4GTW A;  5C66 A;  3T02 A;  4KAY A;  5L0E A;  2W8D A;  5DLV A;  5EGE A;  1Y6V A;  1KHN A;  2IUC B;  3SZZ A;  3NKQ A;  4KJD A;  4MHX A;  1B8J A;  4FDI A;  4CXS A;  1ELZ A;  4LR8 A;  3UN3 A;  1K7H A;  2W5W A;  4CXK A;  2GA3 A;  4LRE A;  1P49 A;  3TX0 A;  5LQQ A;  5GRR A;  3T01 A;  2IFY A;  3Q3Q A;  5EGH A;  5K4P A;  1Y7A A;  3M8Z A;  3BDG A;  1N2L A;  4GTZ A;  1ZEB A;  4MY4 A;  5AJ9 A;  1ZEF A; 
#chains in the Genus database with same CATH topology
 1FSU A;  4GTY A;  2VQR A;  4LR2 A;  3A52 A;  2ANH A;  3IDD A;  2GLQ A;  3BDF A;  1KHL A;  3T00 A;  4QAX A;  4LR9 A;  3UNY A;  1KH4 A;  2XR9 A;  4TN0 A;  3WAX A;  4ZG7 A;  1ALI A;  1EW2 A;  4UPI A;  1O98 A;  1SHN A;  3NKO A;  5IJQ A;  4LQY A;  3IGY B;  1AJA A;  3B5Q A;  4LRA A;  3UN2 A;  3M8Y A;  4UPH A;  3WBH A;  3TG0 A;  4ZG6 A;  5HRT A;  5L0B A;  1ANJ A;  1N2K A;  5KXA A;  4UPL A;  2W5V A;  1E3C P;  5LRN A;  1EJJ A;  3WAW A;  4N7T A;  4GTX A;  1E2S P;  3NKN A;  2X98 A;  4NWX A;  1AJB A;  1KH7 A;  1AJD A;  2D1G A;  3DPC A;  3BDH A;  4LRF A;  3M7V A;  2W5X A;  4KJG A;  4ZGA A;  1AJC A;  2W8S A;  1EW9 A;  1KHJ A;  3IGZ B;  4FDJ A;  5L0K A;  4UPK A;  1ELY A;  2QZU A;  5LRM A;  4MIV A;  1ALJ A;  1E1Z P;  1EI6 A;  3NKR A;  4LR7 A;  3SZY A;  1URB A;  3MK0 A;  4UOP A;  4LRC A;  5DLT A;  4KAV A;  2GSU A;  2RH6 A;  3BDG B;  4LRD A;  2IUC A;  2XRG A;  4CYR A;  1ED8 A;  4UOO A;  2GSO A;  1EQJ A;  4CXU A;  3WAY A;  2GSN A;  2W5Q A;  2ZKT A;  3NVL A;  1ANI A;  3TWZ A;  1ALH A;  3M8W A;  1KH5 A;  2W5R A;  1E33 P;  1O99 A;  2W5T A;  3NKP A;  1HDH A;  5LIA A;  5INH A;  1AUK A;  3LXQ A;  3CMR A;  1ELX A;  2W5S A;  3MK2 A;  1SHQ A;  1ALK A;  3MK1 A;  4B56 A;  1ED9 A;  4ZG9 A;  3UN5 A;  5IJS A;  4KM4 A;  3OT9 A;  4UOR A;  3DYC A;  2G9Y A;  4YR1 A;  1URA A;  3E2D A;  1ZED A;  5TJ3 A;  1HJK A;  3NKM A;  1HQA A;  3UO0 A;  3KD8 A;  4NWJ A;  5GOV A;  3WAV A;  4CYS A;  1EW8 A;  3ED4 A;  5DLW A;  1KHK A;  1KH9 A;  4LRB A;  4GTW A;  5C66 A;  3T02 A;  4KAY A;  5L0E A;  2W8D A;  5DLV A;  5EGE A;  1Y6V A;  1KHN A;  2IUC B;  3SZZ A;  3NKQ A;  4KJD A;  4MHX A;  1B8J A;  4FDI A;  4CXS A;  1ELZ A;  4LR8 A;  3UN3 A;  1K7H A;  2W5W A;  4CXK A;  2GA3 A;  4LRE A;  1P49 A;  3TX0 A;  5LQQ A;  5GRR A;  3T01 A;  2IFY A;  3Q3Q A;  5EGH A;  5K4P A;  1Y7A A;  3M8Z A;  3BDG A;  1N2L A;  4GTZ A;  1ZEB A;  4MY4 A;  5AJ9 A;  1ZEF A; 
#chains in the Genus database with same CATH homology
 1FSU A;  4GTY A;  2VQR A;  4LR2 A;  3A52 A;  2ANH A;  3IDD A;  2GLQ A;  3BDF A;  1KHL A;  3T00 A;  4QAX A;  4LR9 A;  3UNY A;  1KH4 A;  2XR9 A;  4TN0 A;  3WAX A;  4ZG7 A;  1ALI A;  1EW2 A;  4UPI A;  1O98 A;  1SHN A;  3NKO A;  5IJQ A;  4LQY A;  3IGY B;  1AJA A;  3B5Q A;  4LRA A;  3UN2 A;  3M8Y A;  4UPH A;  3WBH A;  3TG0 A;  4ZG6 A;  5HRT A;  5L0B A;  1ANJ A;  1N2K A;  5KXA A;  4UPL A;  2W5V A;  1E3C P;  5LRN A;  1EJJ A;  3WAW A;  4N7T A;  4GTX A;  1E2S P;  3NKN A;  2X98 A;  4NWX A;  1AJB A;  1KH7 A;  1AJD A;  2D1G A;  3DPC A;  3BDH A;  4LRF A;  3M7V A;  2W5X A;  4KJG A;  4ZGA A;  1AJC A;  2W8S A;  1EW9 A;  1KHJ A;  3IGZ B;  4FDJ A;  5L0K A;  4UPK A;  1ELY A;  2QZU A;  5LRM A;  4MIV A;  1ALJ A;  1E1Z P;  1EI6 A;  3NKR A;  4LR7 A;  3SZY A;  1URB A;  3MK0 A;  4UOP A;  4LRC A;  5DLT A;  4KAV A;  2GSU A;  2RH6 A;  3BDG B;  4LRD A;  2IUC A;  2XRG A;  4CYR A;  1ED8 A;  4UOO A;  2GSO A;  1EQJ A;  4CXU A;  3WAY A;  2GSN A;  2W5Q A;  2ZKT A;  3NVL A;  1ANI A;  3TWZ A;  1ALH A;  3M8W A;  1KH5 A;  2W5R A;  1E33 P;  1O99 A;  2W5T A;  3NKP A;  1HDH A;  5LIA A;  5INH A;  1AUK A;  3LXQ A;  3CMR A;  1ELX A;  2W5S A;  3MK2 A;  1SHQ A;  1ALK A;  3MK1 A;  4B56 A;  1ED9 A;  4ZG9 A;  3UN5 A;  5IJS A;  4KM4 A;  3OT9 A;  4UOR A;  3DYC A;  2G9Y A;  4YR1 A;  1URA A;  3E2D A;  1ZED A;  5TJ3 A;  1HJK A;  3NKM A;  1HQA A;  3UO0 A;  3KD8 A;  4NWJ A;  5GOV A;  3WAV A;  4CYS A;  1EW8 A;  3ED4 A;  5DLW A;  1KHK A;  1KH9 A;  4LRB A;  4GTW A;  5C66 A;  3T02 A;  4KAY A;  5L0E A;  2W8D A;  5DLV A;  5EGE A;  1Y6V A;  1KHN A;  2IUC B;  3SZZ A;  3NKQ A;  4KJD A;  4MHX A;  1B8J A;  4FDI A;  4CXS A;  1ELZ A;  4LR8 A;  3UN3 A;  1K7H A;  2W5W A;  4CXK A;  2GA3 A;  4LRE A;  1P49 A;  3TX0 A;  5LQQ A;  5GRR A;  3T01 A;  2IFY A;  3Q3Q A;  5EGH A;  5K4P A;  1Y7A A;  3M8Z A;  3BDG A;  1N2L A;  4GTZ A;  1ZEB A;  4MY4 A;  5AJ9 A;  1ZEF A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...