1ZJDB

Crystal structure of the catalytic domain of coagulation factor xi in complex with kunitz protease inhibitor domain of protease nexin ii
Total Genus 8
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
8
sequence length
57
structure length
57
Chain Sequence
EVCSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVCGSAI
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title Structural and Mutational Analyses of the Molecular Interactions between the Catalytic Domain of Factor XIa and the Kunitz Protease Inhibitor Domain of Protease Nexin 2
pubmed doi rcsb
molecule tags Hydrolase, blood clotting
source organism Homo sapiens
molecule keywords Catalytic Domain of Coagulation Factor XI
total genus 8
structure length 57
sequence length 57
ec nomenclature
pdb deposition date 2005-04-28

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF00014 Kunitz_BPTI Kunitz/Bovine pancreatic trypsin inhibitor domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
4.10.410.10 Few Secondary Structures Irregular Factor Xa Inhibitor Pancreatic trypsin inhibitor Kunitz domain 1zjdB00
5PTIA 4TPII 4WWYC 1IRHA 3OFWA 5JB6A 4ISNB 2JOTA 3BTQI 3TPII 3P95E 3UOUB 1JC6A 3BTFI 1G6XA 1FAKI 2FTLI 6PTIA 3U1JE 1P2MB 1P2KI 1AAPA 3FP8I 4U30W 2ODYE 1T8MB 1DEMA 1K6UA 3P92E 1BRCI 1DTKA 2ZJXA 1BIKA 3AUHA 1DTXA 1JV8A 3BTDI 1FY8I 1SHPA 1TFXC 1OA65 3M7QB 4U32X 4Y0YI 4BNRI 4ISOB 1KUNA 2M99A 4PTIA 1KNTA 3TGII 1UUBA 2R9PE 8PTIA 2TPII 3BTHI 3BTTI 3CI7A 3BTGI 1BHCA 3AUDA 3D65I 1D0DA 1T8LB 1YLDB 1PITA 1BUNB 1LD6A 1B0CA 1AALA 3FP6I 2KNTA 3GYMI 2CA7A 4WXVC 3LDIA 1EJMB 1DENA 1JV9A 3L3TE 1NAGA 2KCRA 2J6DA 9PTIA 2FTMB 1TAPA 2FI5I 1F7ZI 1P2JI 2LFKA 4Y10I 5JB4A 1F5RI 1BPTA 1BTIA 1KIGI 1TOCR 4Y0ZI 5JB5A 1EAWB 3T62D 1QLQA 4NTYB 1CA0D 1Y62A 1OA55 3AUEA 4BD9B 4NTWB 3BTWI 1D0DB 4NTXB 3AUCA 3AUIA 2FI3I 1P2QB 4DTGK 1BZ5A 4BQDA 1KTHA 1CO7I 1MTND 1ZJDB 4Y11I 1P2NB 2UUXA 3AUBA 3TGJI 2KAII 2RA3C 3AUGA 1LD5A 3LDMA 1T8OB 1TPAI 3FP7J 3OTJI 1CBWD 4DG4C 1ZR0B 3BTEI 1BRBI 1YC0I 1YLCB 2DDIA 3UIRC 2DDJA 1P2II 4ISLB 2UUYB 3BYBA 1TCPA 7PTIA 1ADZA 2TGPI 3BTMI 1BPIA 1BZXI 2FI4I 3WNYA 1BF0A 5JB7A 2PTCI 3TGKI 2IJOI 3BTKI 5C67C 1FANA 1T8NB 1UUAA 2ZVXA 2HEXA 3LDJA 1TAWB 2LFLA 3L33E 1T7CB 2W8XA 1P2OB 2M01A 1BTHP 1YKTB
chains in the Genus database with same CATH superfamily
5PTIA 4TPII 4WWYC 1IRHA 3OFWA 5JB6A 4ISNB 2JOTA 3BTQI 3TPII 3P95E 3UOUB 1JC6A 3BTFI 1G6XA 1FAKI 2FTLI 6PTIA 3U1JE 1P2MB 1P2KI 1AAPA 3FP8I 4U30W 2ODYE 1T8MB 1DEMA 1K6UA 3P92E 1BRCI 1DTKA 2ZJXA 1BIKA 3AUHA 1DTXA 1JV8A 3BTDI 1FY8I 1SHPA 1TFXC 1OA65 3M7QB 4U32X 4Y0YI 4BNRI 4ISOB 1KUNA 2M99A 4PTIA 1KNTA 3TGII 1UUBA 2R9PE 8PTIA 2TPII 3BTHI 3BTTI 3CI7A 3BTGI 1BHCA 3AUDA 3D65I 1D0DA 1T8LB 1YLDB 1PITA 1BUNB 1LD6A 1B0CA 1AALA 3FP6I 2KNTA 3GYMI 2CA7A 4WXVC 3LDIA 1EJMB 1DENA 1JV9A 3L3TE 1NAGA 2KCRA 2J6DA 9PTIA 2FTMB 1TAPA 2FI5I 1F7ZI 1P2JI 2LFKA 4Y10I 5JB4A 1F5RI 1BPTA 1BTIA 1KIGI 1TOCR 4Y0ZI 5JB5A 1EAWB 3T62D 1QLQA 4NTYB 1CA0D 1Y62A 1OA55 3AUEA 4BD9B 4NTWB 3BTWI 1D0DB 4NTXB 3AUCA 3AUIA 2FI3I 1P2QB 4DTGK 1BZ5A 4BQDA 1KTHA 1CO7I 1MTND 1ZJDB 4Y11I 1P2NB 2UUXA 3AUBA 3TGJI 2KAII 2RA3C 3AUGA 1LD5A 3LDMA 1T8OB 1TPAI 3FP7J 3OTJI 1CBWD 4DG4C 1ZR0B 3BTEI 1BRBI 1YC0I 1YLCB 2DDIA 3UIRC 2DDJA 1P2II 4ISLB 2UUYB 3BYBA 1TCPA 7PTIA 1ADZA 2TGPI 3BTMI 1BPIA 1BZXI 2FI4I 3WNYA 1BF0A 5JB7A 2PTCI 3TGKI 2IJOI 3BTKI 5C67C 1FANA 1T8NB 1UUAA 2ZVXA 2HEXA 3LDJA 1TAWB 2LFLA 3L33E 1T7CB 2W8XA 1P2OB 2M01A 1BTHP 1YKTB
chains in the Genus database with same CATH topology
5PTIA 4TPII 4WWYC 1IRHA 3OFWA 5JB6A 4ISNB 2JOTA 3BTQI 3TPII 3P95E 3UOUB 1JC6A 3BTFI 1G6XA 1FAKI 2FTLI 6PTIA 3U1JE 1P2MB 1P2KI 1AAPA 3FP8I 4U30W 2ODYE 1T8MB 1DEMA 1K6UA 3P92E 1BRCI 1DTKA 2ZJXA 1BIKA 3AUHA 1DTXA 1JV8A 3BTDI 1FY8I 1SHPA 1TFXC 1OA65 3M7QB 4U32X 4Y0YI 4BNRI 4ISOB 1KUNA 2M99A 4PTIA 1KNTA 3TGII 1UUBA 2R9PE 8PTIA 2TPII 3BTHI 3BTTI 3CI7A 3BTGI 1BHCA 3AUDA 3D65I 1D0DA 1T8LB 1YLDB 1PITA 1BUNB 1LD6A 1B0CA 1AALA 3FP6I 2KNTA 3GYMI 2CA7A 4WXVC 3LDIA 1EJMB 1DENA 1JV9A 3L3TE 1NAGA 2KCRA 2J6DA 9PTIA 2FTMB 1TAPA 2FI5I 1F7ZI 1P2JI 2LFKA 4Y10I 5JB4A 1F5RI 1BPTA 1BTIA 1KIGI 1TOCR 4Y0ZI 5JB5A 1EAWB 3T62D 1QLQA 4NTYB 1CA0D 1Y62A 1OA55 3AUEA 4BD9B 4NTWB 3BTWI 1D0DB 4NTXB 3AUCA 3AUIA 2FI3I 1P2QB 4DTGK 1BZ5A 4BQDA 1KTHA 1CO7I 1MTND 1ZJDB 4Y11I 1P2NB 2UUXA 3AUBA 3TGJI 2KAII 2RA3C 3AUGA 1LD5A 3LDMA 1T8OB 1TPAI 3FP7J 3OTJI 1CBWD 4DG4C 1ZR0B 3BTEI 1BRBI 1YC0I 1YLCB 2DDIA 3UIRC 2DDJA 1P2II 4ISLB 2UUYB 3BYBA 1TCPA 7PTIA 1ADZA 2TGPI 3BTMI 1BPIA 1BZXI 2FI4I 3WNYA 1BF0A 5JB7A 2PTCI 3TGKI 2IJOI 3BTKI 5C67C 1FANA 1T8NB 1UUAA 2ZVXA 2HEXA 3LDJA 1TAWB 2LFLA 3L33E 1T7CB 2W8XA 1P2OB 2M01A 1BTHP 1YKTB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5PTI A;  4TPI I;  4WWY C;  1IRH A;  3OFW A;  5JB6 A;  4ISN B;  2JOT A;  3BTQ I;  3TPI I;  3P95 E;  3UOU B;  1JC6 A;  3BTF I;  1G6X A;  1FAK I;  2FTL I;  6PTI A;  3U1J E;  1P2M B;  1P2K I;  1AAP A;  3FP8 I;  4U30 W;  2ODY E;  1T8M B;  1DEM A;  1K6U A;  3P92 E;  1BRC I;  1DTK A;  2ZJX A;  1BIK A;  3AUH A;  1DTX A;  1JV8 A;  3BTD I;  1FY8 I;  1SHP A;  1TFX C;  1OA6 5;  3M7Q B;  4U32 X;  4Y0Y I;  4BNR I;  4ISO B;  1KUN A;  2M99 A;  4PTI A;  1KNT A;  3TGI I;  1UUB A;  2R9P E;  8PTI A;  2TPI I;  3BTH I;  3BTT I;  3CI7 A;  3BTG I;  1BHC A;  3AUD A;  3D65 I;  1D0D A;  1T8L B;  1YLD B;  1PIT A;  1BUN B;  1LD6 A;  1B0C A;  1AAL A;  3FP6 I;  2KNT A;  3GYM I;  2CA7 A;  4WXV C;  3LDI A;  1EJM B;  1DEN A;  1JV9 A;  3L3T E;  1NAG A;  2KCR A;  2J6D A;  9PTI A;  2FTM B;  1TAP A;  2FI5 I;  1F7Z I;  1P2J I;  2LFK A;  4Y10 I;  5JB4 A;  1F5R I;  1BPT A;  1BTI A;  1KIG I;  1TOC R;  4Y0Z I;  5JB5 A;  1EAW B;  3T62 D;  1QLQ A;  4NTY B;  1CA0 D;  1Y62 A;  1OA5 5;  3AUE A;  4BD9 B;  4NTW B;  3BTW I;  1D0D B;  4NTX B;  3AUC A;  3AUI A;  2FI3 I;  1P2Q B;  4DTG K;  1BZ5 A;  4BQD A;  1KTH A;  1CO7 I;  1MTN D;  1ZJD B;  4Y11 I;  1P2N B;  2UUX A;  3AUB A;  3TGJ I;  2KAI I;  2RA3 C;  3AUG A;  1LD5 A;  3LDM A;  1T8O B;  1TPA I;  3FP7 J;  3OTJ I;  1CBW D;  4DG4 C;  1ZR0 B;  3BTE I;  1BRB I;  1YC0 I;  1YLC B;  2DDI A;  3UIR C;  2DDJ A;  1P2I I;  4ISL B;  2UUY B;  3BYB A;  1TCP A;  7PTI A;  1ADZ A;  2TGP I;  3BTM I;  1BPI A;  1BZX I;  2FI4 I;  3WNY A;  1BF0 A;  5JB7 A;  2PTC I;  3TGK I;  2IJO I;  3BTK I;  5C67 C;  1FAN A;  1T8N B;  1UUA A;  2ZVX A;  2HEX A;  3LDJ A;  1TAW B;  2LFL A;  3L33 E;  1T7C B;  2W8X A;  1P2O B;  2M01 A;  1BTH P;  1YKT B; 
#chains in the Genus database with same CATH topology
 5PTI A;  4TPI I;  4WWY C;  1IRH A;  3OFW A;  5JB6 A;  4ISN B;  2JOT A;  3BTQ I;  3TPI I;  3P95 E;  3UOU B;  1JC6 A;  3BTF I;  1G6X A;  1FAK I;  2FTL I;  6PTI A;  3U1J E;  1P2M B;  1P2K I;  1AAP A;  3FP8 I;  4U30 W;  2ODY E;  1T8M B;  1DEM A;  1K6U A;  3P92 E;  1BRC I;  1DTK A;  2ZJX A;  1BIK A;  3AUH A;  1DTX A;  1JV8 A;  3BTD I;  1FY8 I;  1SHP A;  1TFX C;  1OA6 5;  3M7Q B;  4U32 X;  4Y0Y I;  4BNR I;  4ISO B;  1KUN A;  2M99 A;  4PTI A;  1KNT A;  3TGI I;  1UUB A;  2R9P E;  8PTI A;  2TPI I;  3BTH I;  3BTT I;  3CI7 A;  3BTG I;  1BHC A;  3AUD A;  3D65 I;  1D0D A;  1T8L B;  1YLD B;  1PIT A;  1BUN B;  1LD6 A;  1B0C A;  1AAL A;  3FP6 I;  2KNT A;  3GYM I;  2CA7 A;  4WXV C;  3LDI A;  1EJM B;  1DEN A;  1JV9 A;  3L3T E;  1NAG A;  2KCR A;  2J6D A;  9PTI A;  2FTM B;  1TAP A;  2FI5 I;  1F7Z I;  1P2J I;  2LFK A;  4Y10 I;  5JB4 A;  1F5R I;  1BPT A;  1BTI A;  1KIG I;  1TOC R;  4Y0Z I;  5JB5 A;  1EAW B;  3T62 D;  1QLQ A;  4NTY B;  1CA0 D;  1Y62 A;  1OA5 5;  3AUE A;  4BD9 B;  4NTW B;  3BTW I;  1D0D B;  4NTX B;  3AUC A;  3AUI A;  2FI3 I;  1P2Q B;  4DTG K;  1BZ5 A;  4BQD A;  1KTH A;  1CO7 I;  1MTN D;  1ZJD B;  4Y11 I;  1P2N B;  2UUX A;  3AUB A;  3TGJ I;  2KAI I;  2RA3 C;  3AUG A;  1LD5 A;  3LDM A;  1T8O B;  1TPA I;  3FP7 J;  3OTJ I;  1CBW D;  4DG4 C;  1ZR0 B;  3BTE I;  1BRB I;  1YC0 I;  1YLC B;  2DDI A;  3UIR C;  2DDJ A;  1P2I I;  4ISL B;  2UUY B;  3BYB A;  1TCP A;  7PTI A;  1ADZ A;  2TGP I;  3BTM I;  1BPI A;  1BZX I;  2FI4 I;  3WNY A;  1BF0 A;  5JB7 A;  2PTC I;  3TGK I;  2IJO I;  3BTK I;  5C67 C;  1FAN A;  1T8N B;  1UUA A;  2ZVX A;  2HEX A;  3LDJ A;  1TAW B;  2LFL A;  3L33 E;  1T7C B;  2W8X A;  1P2O B;  2M01 A;  1BTH P;  1YKT B; 
#chains in the Genus database with same CATH homology
 5PTI A;  4TPI I;  4WWY C;  1IRH A;  3OFW A;  5JB6 A;  4ISN B;  2JOT A;  3BTQ I;  3TPI I;  3P95 E;  3UOU B;  1JC6 A;  3BTF I;  1G6X A;  1FAK I;  2FTL I;  6PTI A;  3U1J E;  1P2M B;  1P2K I;  1AAP A;  3FP8 I;  4U30 W;  2ODY E;  1T8M B;  1DEM A;  1K6U A;  3P92 E;  1BRC I;  1DTK A;  2ZJX A;  1BIK A;  3AUH A;  1DTX A;  1JV8 A;  3BTD I;  1FY8 I;  1SHP A;  1TFX C;  1OA6 5;  3M7Q B;  4U32 X;  4Y0Y I;  4BNR I;  4ISO B;  1KUN A;  2M99 A;  4PTI A;  1KNT A;  3TGI I;  1UUB A;  2R9P E;  8PTI A;  2TPI I;  3BTH I;  3BTT I;  3CI7 A;  3BTG I;  1BHC A;  3AUD A;  3D65 I;  1D0D A;  1T8L B;  1YLD B;  1PIT A;  1BUN B;  1LD6 A;  1B0C A;  1AAL A;  3FP6 I;  2KNT A;  3GYM I;  2CA7 A;  4WXV C;  3LDI A;  1EJM B;  1DEN A;  1JV9 A;  3L3T E;  1NAG A;  2KCR A;  2J6D A;  9PTI A;  2FTM B;  1TAP A;  2FI5 I;  1F7Z I;  1P2J I;  2LFK A;  4Y10 I;  5JB4 A;  1F5R I;  1BPT A;  1BTI A;  1KIG I;  1TOC R;  4Y0Z I;  5JB5 A;  1EAW B;  3T62 D;  1QLQ A;  4NTY B;  1CA0 D;  1Y62 A;  1OA5 5;  3AUE A;  4BD9 B;  4NTW B;  3BTW I;  1D0D B;  4NTX B;  3AUC A;  3AUI A;  2FI3 I;  1P2Q B;  4DTG K;  1BZ5 A;  4BQD A;  1KTH A;  1CO7 I;  1MTN D;  1ZJD B;  4Y11 I;  1P2N B;  2UUX A;  3AUB A;  3TGJ I;  2KAI I;  2RA3 C;  3AUG A;  1LD5 A;  3LDM A;  1T8O B;  1TPA I;  3FP7 J;  3OTJ I;  1CBW D;  4DG4 C;  1ZR0 B;  3BTE I;  1BRB I;  1YC0 I;  1YLC B;  2DDI A;  3UIR C;  2DDJ A;  1P2I I;  4ISL B;  2UUY B;  3BYB A;  1TCP A;  7PTI A;  1ADZ A;  2TGP I;  3BTM I;  1BPI A;  1BZX I;  2FI4 I;  3WNY A;  1BF0 A;  5JB7 A;  2PTC I;  3TGK I;  2IJO I;  3BTK I;  5C67 C;  1FAN A;  1T8N B;  1UUA A;  2ZVX A;  2HEX A;  3LDJ A;  1TAW B;  2LFL A;  3L33 E;  1T7C B;  2W8X A;  1P2O B;  2M01 A;  1BTH P;  1YKT B; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...