2A3KA

Crystal structure of the human protein tyrosine phosphatase, ptpn7 (heptp, hematopoietic protein tyrosine phosphatase)
Total Genus 90
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
90
sequence length
294
structure length
272
Chain Sequence
NTPREVTLHFLRTAGHPLTRWALQRQPPSPKQLEEEFLKIPSNFVSPEDLDIPGHASKDRYKTILPNPQSRVCLGDYINANYIRGYDGKEKVYIATQGPMPNTVSDFWEMVWQEEVSLIVMLTQLRVHYWPTEEETYGPFQIRIQDMKECPEYTVRQLTIQYQEERRSVKHILFSAWPDHQTPESAGPLLRLVAEVEEGPIVVHCSAGIGRTGCFIATRIGCQQLKARGEVDILGIVCQLRLDRGGMIQTAEQYQFLHHTLALYAGQLPEEP
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The crystal structure of human receptor protein tyrosine phosphatase kappa phosphatase domain 1.
pubmed doi rcsb
molecule tags Signaling protein
source organism Homo sapiens
molecule keywords protein tyrosine phosphatase, non-receptor type 7, isoform 1
total genus 90
structure length 272
sequence length 294
ec nomenclature ec 3.1.3.48: Protein-tyrosine-phosphatase.
pdb deposition date 2005-06-24

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00102 Y_phosphatase Protein-tyrosine phosphatase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.190.10 Alpha Beta Alpha-Beta Complex Protein-Tyrosine Phosphatase; Chain A Protein tyrosine phosphatase superfamily 2a3kA00
3QCDA 5K9VA 2CFVA 2VEUA 5KA8A 4GE6A 1Q1MA 2I3UA 2FJNA 2PT0A 2H4GA 4QBEA 5EHPA 1FPRA 1U24A 3BLUA 2ZN7A 1YGRA 3QKQA 2F6YA 1G4US 3AWGA 1D5RA 5M43A 3V0FA 2HXPA 2G6ZA 1R6HA 5BZZA 5IBSA 2I6OA 5KA9A 2HB1A 2B4SA 4ZI4A 2I4HA 4HJQA 4HJPA 2QCJA 4RI5A 3B7OA 4JMKA 3S3EA 2G59A 4TVVA 3F81A 1OHDA 1LARA 4WU3A 1NO6A 5KAAA 2MBCA 3QCGA 3O4UA 2SHPA 3LJ8A 4Y14A 3ZV2A 2F6FA 4GRZA 1U25A 2R0BA 4J51A 1YGUA 1MKPA 2CM7A 2HCMA 3U96A 1PTTA 1M3GA 1JLNA 2I4GA 3O4SA 3SR9A 3EZZA 4S0GA 2H4VA 1YTNA 3D44A 4R30A 4D3PA 2F6TA 4R0SA 2QDPA 2I3RA 2VEYA 2ZMMA 2NV5A 2I4EA 1BZHA 5BX1A 3CM3A 2P6XA 3QKPA 3EAXA 2CMAA 4QUNA 3V0HA 2OC3A 1ONYA 5BUGA 1Q6SA 1PA9A 4RDDA 2HNQA 5BZXA 1I57A 2FH7A 4NX8A 2YDUA 4YR8B 2CM3A 1I9SA 5LXQB 5MMZB 5K25A 1OEMX 3OLRA 2I6JA 1EENA 1VHRA 2QEPA 1T4JA 4I8NA 1QZ0A 1NL9A 3V0IA 2CMCA 1BZJA 4RI4A 2P4DA 2PBNA 2IMGA 2QCTA 2PSZA 2F46A 4GE2A 4PVGA 4NWGA 1Q6NA 2NLKA 1OHCA 1PH0A 2A8BA 5K9WA 2PI7A 2F71A 2I6MA 5KA2A 1OEUA 3RGQA 2GWOA 1PA1A 2I75A 3QCBA 3AWEA 4OHDA 1V3AA 2A3KA 3V0JA 2CNIA 5KA4A 2BGEA 2C46A 4OHHA 1NWEA 4GRYA 3QCHA 3ZM3A 2JJDA 4GS0A 2H04A 1Q6MA 1ZCKA 4BJOA 3RZ2A 2Y2FA 3O3LA 4D3RA 4WOHA 4R0TA 3QCCA 3ZM1A 1ZCLA 5I6VA 2CNEA 2GJTA 4KYRA 2I42A 1G1GA 3QCIA 1XM2A 4JNBA 1C86A 3A5KA 3S4EA 2B49A 2BZLA 1XRIA 3RGOA 2QBRA 3OMHA 4ERCA 5HDEA 1XBOA 1G7GA 3BM8A 3F41A 5AWXA 3GXHA 2B3OA 4KYQA 2FJMA 3QCJA 2CNHA 3AWFA 2I1YA 3D1HA 5EHRA 3MMJA 1WCHA 3MOWA 4H34A 5KA3A 2NT7A 1ONZA 2J16B 2HVLA 1LYVA 2I6IA 3F9BA 2HC1A 2OOQA 3D1OA 2HC2A 1L8GA 1NZ7A 2OUDA 2I6PA 2QDMA 1XXPA 3ZMPA 4QUMA 3RO1A 2B4OA 3QCMA 4Y2EA 3M4UA 3V0GA 4DGPA 2CJZA 1PXHA 3N0AA 1L8KA 2J17A 4GFUA 1KAVA 3QCNA 2DXPA 4RH9A 4QBWA 1G4WR 1T48A 2H02A 2BIJA 1NWLA 4JMJA 3I36A 2E0TA 3D42A 1G1HA 4ICZA 2WGPA 5K24A 1Q6TA 1YN9A 2Q05A 4GE5A 2F6WA 3S3HA 3F9AA 5K22A 1EEOA 1C88A 2F6ZA 1ZZWA 4IKCA 3SMEA 4GFVA 2Y96A 1C84A 1OHEA 5KA0A 4OHEA 5KA7A 2OZ5A 1YZ4A 1WRMA 2AZRA 2BV5A 3BRHA 1I9TA 3EMUA 4KI9A 2NT2A 1C83A 4WTYA 2PA5A 4DGXA 4MBBA 2QDCA 1XXVA 2VEVA 4AZ1A 5GTJA 1NNYA 1YPTA 2ESBA 2I5XA 1GWZA 2GP0A 4NNDA 3EB1A 1T49A 4QAHA 3ZM2A 1BZCA 3O4TA 2M3VA 1C87A 2QBQA 1KAKA 5J8RA 2Q47A 2CM2A 1OEOX 1JF7A 3F99A 2AHSA 4QAPA 5IBMA 3D1QA 2H03A 2VEWA 3I80A 2PQ5A 5KACA 3QCKA 1Q6PA 4BPCA 1YWFA 4H1OA 2CM8A 2VEXA 3EU0A 2CNFA 1G7FA 4RHGA 4OHLA 3QCEA 4ZN5A 3ZMQA 2C7SA 2QBSA 2B4PA 2NZ6A 1X24A 5KADA 2NTAA 1A5YA 2RF6A 1PYNA 3H2XA 1P15A 5K23A 4Z6BA 4GWFA 1RXDA 1PTUA 4PYHA 3V0EA 3QCLA 1QXKA 1ECVA 1SUGA 1WAXA 4RH5A 3ZM0A 2BGDA 3I7ZA 2F70A 3CWEA 2B07A 2HY3A 4NYHA 4B04A 1J4XA 1ZC0A 2J16A 3S3KA 3S3FA 2H4KA 1OETA 1AAXA 1PTVA 3V0DA 1YTWA 1PTYA 4NWFA 1OEVA 1YTSA 1Q6JA 5KA1A 4OHIA 2B4UA 2F6VA 3MOZA 2QBPA 2HNPA 3A5JA 1G1FA 1LQFA 4JBCA 1OESA 3BLTA 5KABA 3NMEA 4RKKA 1GFYA 2CMBA 4YAAA 4ZRTA 3GXGA 1RPMA 3S4OA 3QCFA 4D3QA 4HRFA 3D9CA 3PS5A 1YFOA 1FPZA 3O5XA 1FQ1A 4WU2A 2CNGA 1C85A 1U26A
chains in the Genus database with same CATH superfamily
3QCDA 5K9VA 2Y68A 2CFVA 2VEUA 3HN7A 5KA8A 1P31A 4GE6A 1Q1MA 2I3UA 2FJNA 2GC5A 2PT0A 2H4GA 4QBEA 5EHPA 1FPRA 1U24A 3BLUA 2ZN7A 1YGRA 3QKQA 2F6YA 1G4US 3AWGA 1D5RA 5M43A 2VTEA 3V0FA 2HXPA 2G6ZA 4ZIYA 1R6HA 5BZZA 5IBSA 2I6OA 5KA9A 2HB1A 2B4SA 4ZI4A 2I4HA 4HJQA 4HJPA 2QCJA 4RI5A 3B7OA 4JMKA 3S3EA 4CVLA 2G59A 4TVVA 3F81A 1OHDA 1LARA 4WU3A 1NO6A 5KAAA 2MBCA 3QCGA 3O4UA 2SHPA 3LJ8A 4Y14A 3ZV2A 2JFHA 1E0DA 2F6FA 4GRZA 4UAGA 4C13A 1U25A 2R0BA 4J51A 4BUBA 1UAGA 1MKPA 1YGUA 2CM7A 2HCMA 2VTDA 3U96A 1PTTA 1M3GA 1JLNA 2I4GA 3O4SA 2WTZA 3SR9A 3EZZA 4S0GA 2H4VA 1YTNA 3D44A 4R30A 4D3PA 2F6TA 4R0SA 2QDPA 2I3RA 2VEYA 2ZMMA 2NV5A 2I4EA 1BZHA 5BX1A 3CM3A 2P6XA 2XJAA 3QKPA 3EAXA 2CMAA 4QUNA 3V0HA 2OC3A 1ONYA 4BUCA 2X5OA 5BUGA 5A5EA 1Q6SA 1PA9A 4RDDA 2HNQA 5BZXA 1I57A 2FH7A 4NX8A 2YDUA 4YR8B 2CM3A 1E8CA 1I9SA 5LXQB 5MMZB 2WJPA 5K25A 1OEMX 3OLRA 2I6JA 1EENA 1VHRA 2QEPA 1T4JA 4I8NA 1QZ0A 1NL9A 3V0IA 2CMCA 1BZJA 4RI4A 2P4DA 2PBNA 2IMGA 2QCTA 1GQQA 2PSZA 2F46A 4GE2A 4PVGA 4NWGA 1Q6NA 2NLKA 1OHCA 1PH0A 2A8BA 5K9WA 2PI7A 2F71A 2I6MA 5KA2A 1OEUA 3RGQA 2GWOA 1PA1A 2I75A 3QCBA 3AWEA 4OHDA 1V3AA 2A3KA 3V0JA 2CNIA 5KA4A 5A5FA 2BGEA 2VOSA 2C46A 4OHHA 1NWEA 4GRYA 3QCHA 3ZM3A 2JJDA 4GS0A 2H04A 1Q6MA 1ZCKA 4BJOA 3RZ2A 2Y2FA 3O3LA 4D3RA 4WOHA 4R0TA 3QCCA 1JBWA 1ZCLA 3ZM1A 5I6VA 2CNEA 2VORA 2GJTA 4KYRA 2I42A 1G1GA 3QCIA 1XM2A 4JNBA 1C86A 3A5KA 3S4EA 2B49A 2BZLA 1XRIA 3RGOA 2QBRA 3OMHA 4ERCA 5HDEA 1XBOA 1G7GA 3BM8A 3F41A 1W7KA 5AWXA 3GXHA 2B3OA 4KYQA 2FJMA 3QCJA 2CNHA 3AWFA 2I1YA 3D1HA 5EHRA 3MMJA 1WCHA 3MOWA 4H34A 5KA3A 2NT7A 1ONZA 2J16B 2HVLA 1LYVA 2I6IA 3F9BA 2HC1A 2OOQA 3D1OA 4CVKA 2HC2A 1L8GA 2JFFA 1NZ7A 2OUDA 2I6PA 2QDMA 1XXPA 2AM2A 4C12A 3ZMPA 3QCZA 4QUMA 3RO1A 2B4OA 3QCMA 4Y2EA 3LK7A 3PYZA 3M4UA 3V0GA 4DGPA 2Y67A 2CJZA 1PXHA 3N0AA 1L8KA 2J17A 4GFUA 1KAVA 3QCNA 1FGSA 2DXPA 4RH9A 4QBWA 1G4WR 1T48A 2H02A 2BIJA 1NWLA 4JMJA 3I36A 2E0TA 3D42A 1G1HA 4ICZA 2WGPA 4QF5A 1Q6TA 5K24A 1YN9A 2Q05A 4GE5A 2F6WA 3UAGA 2GC6A 3S3HA 3F9AA 5K22A 1EEOA 1C88A 2F6ZA 1ZZWA 4IKCA 2Y1OA 3SMEA 1GG4A 4GFVA 2Y96A 1C84A 1OHEA 5KA0A 4OHEA 5KA7A 2OZ5A 1YZ4A 1WRMA 1EEHA 2AZRA 3ZM5A 2BV5A 3BRHA 1I9TA 3EMUA 4KI9A 2NT2A 1C83A 4WTYA 2PA5A 2GCAA 4DGXA 4MBBA 2QDCA 1XXVA 2VEVA 4AZ1A 5GTJA 1NNYA 1YPTA 3MVNA 2ESBA 2I5XA 1GWZA 3NRSA 2GP0A 4NNDA 1P3DA 3EB1A 1T49A 4QAHA 3ZM2A 1BZCA 3O4TA 2M3VA 1C87A 2QBQA 1J6UA 1KAKA 5J8RA 2Q47A 2AM1A 2CM2A 1OEOX 1JF7A 3F99A 2AHSA 4QAPA 5IBMA 3D1QA 2H03A 2VEWA 3I80A 2PQ5A 5KACA 3QCKA 2UAGA 4QDIA 1Q6PA 4BPCA 1YWFA 1GQYA 4H1OA 2CM8A 2VEXA 3EU0A 2CNFA 1G7FA 2XPCA 4RHGA 4OHLA 3QCEA 4ZN5A 3ZMQA 3ZL8A 2C7SA 2QBSA 2B4PA 3ZM6A 2NZ6A 1W78A 1X24A 5KADA 2NTAA 1A5YA 2RF6A 1PYNA 3H2XA 1P15A 2GCBA 4CVMA 5K23A 4Z6BA 2JFGA 4GWFA 1RXDA 1PTUA 4PYHA 3V0EA 3QCLA 1QXKA 1ECVA 1SUGA 1WAXA 4RH5A 3ZM0A 2BGDA 3I7ZA 2F70A 3CWEA 2B07A 2HY3A 4NYHA 4HV4A 4B04A 1J4XA 1ZC0A 2J16A 3S3KA 3S3FA 2H4KA 2Y66A 1OETA 1AAXA 1PTVA 3V0DA 1YTWA 1PTYA 4NWFA 1OEVA 1YTSA 1Q6JA 5KA1A 4OHIA 2B4UA 2F6VA 3MOZA 2F00A 2QBPA 1O5ZA 2HNPA 3A5JA 1G1FA 2UUOA 1LQFA 4JBCA 1OESA 3BLTA 2UUPA 1JBVA 3NMEA 5KABA 4RKKA 1GFYA 2CMBA 4YAAA 4ZRTA 3GXGA 1RPMA 3S4OA 3QCFA 4D3QA 4HRFA 3D9CA 3N2AA 3PS5A 1YFOA 1FPZA 3O5XA 1FQ1A 4WU2A 2CNGA 1C85A 1U26A
chains in the Genus database with same CATH topology
3QCDA 5K9VA 2CFVA 2VEUA 5KA8A 4GE6A 1Q1MA 2I3UA 2FJNA 2PT0A 2H4GA 4QBEA 5EHPA 1FPRA 1U24A 3BLUA 2ZN7A 1YGRA 3QKQA 2F6YA 1G4US 3AWGA 1D5RA 5M43A 3V0FA 2HXPA 2G6ZA 1R6HA 5BZZA 5IBSA 2I6OA 5KA9A 2HB1A 2B4SA 4ZI4A 2I4HA 4HJQA 4HJPA 2QCJA 4RI5A 3B7OA 4JMKA 3S3EA 2G59A 4TVVA 3F81A 1OHDA 1LARA 4WU3A 1NO6A 5KAAA 2MBCA 3QCGA 3O4UA 2SHPA 3LJ8A 4Y14A 3ZV2A 2F6FA 4GRZA 1U25A 2R0BA 4J51A 1YGUA 1MKPA 2CM7A 2HCMA 3U96A 1PTTA 1M3GA 1JLNA 2I4GA 3O4SA 3SR9A 3EZZA 4S0GA 2H4VA 1YTNA 3D44A 4R30A 4D3PA 2F6TA 4R0SA 2QDPA 2I3RA 2VEYA 2ZMMA 2NV5A 2I4EA 1BZHA 5BX1A 3CM3A 2P6XA 3QKPA 3EAXA 2CMAA 4QUNA 3V0HA 2OC3A 1ONYA 5BUGA 1Q6SA 1PA9A 4RDDA 2HNQA 5BZXA 1I57A 2FH7A 4NX8A 2YDUA 4YR8B 2CM3A 1I9SA 5LXQB 5MMZB 5K25A 1OEMX 3OLRA 2I6JA 1EENA 1VHRA 2QEPA 1T4JA 4I8NA 1QZ0A 1NL9A 3V0IA 2CMCA 1BZJA 4RI4A 2P4DA 2PBNA 2IMGA 2QCTA 2PSZA 2F46A 4GE2A 4PVGA 4NWGA 1Q6NA 2NLKA 1OHCA 1PH0A 2A8BA 5K9WA 2PI7A 2F71A 2I6MA 5KA2A 1OEUA 3RGQA 2GWOA 1PA1A 2I75A 3QCBA 3AWEA 4OHDA 1V3AA 2A3KA 3V0JA 2CNIA 5KA4A 2BGEA 2C46A 4OHHA 1NWEA 4GRYA 3QCHA 3ZM3A 2JJDA 4GS0A 2H04A 1Q6MA 1ZCKA 4BJOA 3RZ2A 2Y2FA 3O3LA 4D3RA 4WOHA 4R0TA 3QCCA 3ZM1A 1ZCLA 5I6VA 2CNEA 2GJTA 4KYRA 2I42A 1G1GA 3QCIA 1XM2A 4JNBA 1C86A 3A5KA 3S4EA 2B49A 2BZLA 1XRIA 3RGOA 2QBRA 3OMHA 4ERCA 5HDEA 1XBOA 1G7GA 3BM8A 3F41A 5AWXA 3GXHA 2B3OA 4KYQA 2FJMA 3QCJA 2CNHA 3AWFA 2I1YA 3D1HA 5EHRA 3MMJA 1WCHA 3MOWA 4H34A 5KA3A 2NT7A 1ONZA 2J16B 2HVLA 1LYVA 2I6IA 3F9BA 2HC1A 2OOQA 3D1OA 2HC2A 1L8GA 1NZ7A 2OUDA 2I6PA 2QDMA 1XXPA 3ZMPA 4QUMA 3RO1A 2B4OA 3QCMA 4Y2EA 3M4UA 3V0GA 4DGPA 2CJZA 1PXHA 3N0AA 1L8KA 2J17A 4GFUA 1KAVA 3QCNA 2DXPA 4RH9A 4QBWA 1G4WR 1T48A 2H02A 2BIJA 1NWLA 4JMJA 3I36A 2E0TA 3D42A 1G1HA 4ICZA 2WGPA 5K24A 1Q6TA 1YN9A 2Q05A 4GE5A 2F6WA 3S3HA 3F9AA 5K22A 1EEOA 1C88A 2F6ZA 1ZZWA 4IKCA 3SMEA 4GFVA 2Y96A 1C84A 1OHEA 5KA0A 4OHEA 5KA7A 2OZ5A 1YZ4A 1WRMA 2AZRA 2BV5A 3BRHA 1I9TA 3EMUA 4KI9A 2NT2A 1C83A 4WTYA 2PA5A 4DGXA 4MBBA 2QDCA 1XXVA 2VEVA 4AZ1A 5GTJA 1NNYA 1YPTA 2ESBA 2I5XA 1GWZA 2GP0A 4NNDA 3EB1A 1T49A 4QAHA 3ZM2A 1BZCA 3O4TA 2M3VA 1C87A 2QBQA 1KAKA 5J8RA 2Q47A 2CM2A 1OEOX 1JF7A 3F99A 2AHSA 4QAPA 5IBMA 3D1QA 2H03A 2VEWA 3I80A 2PQ5A 5KACA 3QCKA 1Q6PA 4BPCA 1YWFA 4H1OA 2CM8A 2VEXA 3EU0A 2CNFA 1G7FA 4RHGA 4OHLA 3QCEA 4ZN5A 3ZMQA 2C7SA 2QBSA 2B4PA 2NZ6A 1X24A 5KADA 2NTAA 1A5YA 2RF6A 1PYNA 3H2XA 1P15A 5K23A 4Z6BA 4GWFA 1RXDA 1PTUA 4PYHA 3V0EA 3QCLA 1QXKA 1ECVA 1SUGA 1WAXA 4RH5A 3ZM0A 2BGDA 3I7ZA 2F70A 3CWEA 2B07A 2HY3A 4NYHA 4B04A 1J4XA 1ZC0A 2J16A 3S3KA 3S3FA 2H4KA 1OETA 1AAXA 1PTVA 3V0DA 1YTWA 1PTYA 4NWFA 1OEVA 1YTSA 1Q6JA 5KA1A 4OHIA 2B4UA 2F6VA 3MOZA 2QBPA 2HNPA 3A5JA 1G1FA 1LQFA 4JBCA 1OESA 3BLTA 5KABA 3NMEA 4RKKA 1GFYA 2CMBA 4YAAA 4ZRTA 3GXGA 1RPMA 3S4OA 3QCFA 4D3QA 4HRFA 3D9CA 3PS5A 1YFOA 1FPZA 3O5XA 1FQ1A 4WU2A 2CNGA 1C85A 1U26A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3QCD A;  5K9V A;  2CFV A;  2VEU A;  5KA8 A;  4GE6 A;  1Q1M A;  2I3U A;  2FJN A;  2PT0 A;  2H4G A;  4QBE A;  5EHP A;  1FPR A;  1U24 A;  3BLU A;  2ZN7 A;  1YGR A;  3QKQ A;  2F6Y A;  1G4U S;  3AWG A;  1D5R A;  5M43 A;  3V0F A;  2HXP A;  2G6Z A;  1R6H A;  5BZZ A;  5IBS A;  2I6O A;  5KA9 A;  2HB1 A;  2B4S A;  4ZI4 A;  2I4H A;  4HJQ A;  4HJP A;  2QCJ A;  4RI5 A;  3B7O A;  4JMK A;  3S3E A;  2G59 A;  4TVV A;  3F81 A;  1OHD A;  1LAR A;  4WU3 A;  1NO6 A;  5KAA A;  2MBC A;  3QCG A;  3O4U A;  2SHP A;  3LJ8 A;  4Y14 A;  3ZV2 A;  2F6F A;  4GRZ A;  1U25 A;  2R0B A;  4J51 A;  1YGU A;  1MKP A;  2CM7 A;  2HCM A;  3U96 A;  1PTT A;  1M3G A;  1JLN A;  2I4G A;  3O4S A;  3SR9 A;  3EZZ A;  4S0G A;  2H4V A;  1YTN A;  3D44 A;  4R30 A;  4D3P A;  2F6T A;  4R0S A;  2QDP A;  2I3R A;  2VEY A;  2ZMM A;  2NV5 A;  2I4E A;  1BZH A;  5BX1 A;  3CM3 A;  2P6X A;  3QKP A;  3EAX A;  2CMA A;  4QUN A;  3V0H A;  2OC3 A;  1ONY A;  5BUG A;  1Q6S A;  1PA9 A;  4RDD A;  2HNQ A;  5BZX A;  1I57 A;  2FH7 A;  4NX8 A;  2YDU A;  4YR8 B;  2CM3 A;  1I9S A;  5LXQ B;  5MMZ B;  5K25 A;  1OEM X;  3OLR A;  2I6J A;  1EEN A;  1VHR A;  2QEP A;  1T4J A;  4I8N A;  1QZ0 A;  1NL9 A;  3V0I A;  2CMC A;  1BZJ A;  4RI4 A;  2P4D A;  2PBN A;  2IMG A;  2QCT A;  2PSZ A;  2F46 A;  4GE2 A;  4PVG A;  4NWG A;  1Q6N A;  2NLK A;  1OHC A;  1PH0 A;  2A8B A;  5K9W A;  2PI7 A;  2F71 A;  2I6M A;  5KA2 A;  1OEU A;  3RGQ A;  2GWO A;  1PA1 A;  2I75 A;  3QCB A;  3AWE A;  4OHD A;  1V3A A;  2A3K A;  3V0J A;  2CNI A;  5KA4 A;  2BGE A;  2C46 A;  4OHH A;  1NWE A;  4GRY A;  3QCH A;  3ZM3 A;  2JJD A;  4GS0 A;  2H04 A;  1Q6M A;  1ZCK A;  4BJO A;  3RZ2 A;  2Y2F A;  3O3L A;  4D3R A;  4WOH A;  4R0T A;  3QCC A;  3ZM1 A;  1ZCL A;  5I6V A;  2CNE A;  2GJT A;  4KYR A;  2I42 A;  1G1G A;  3QCI A;  1XM2 A;  4JNB A;  1C86 A;  3A5K A;  3S4E A;  2B49 A;  2BZL A;  1XRI A;  3RGO A;  2QBR A;  3OMH A;  4ERC A;  5HDE A;  1XBO A;  1G7G A;  3BM8 A;  3F41 A;  5AWX A;  3GXH A;  2B3O A;  4KYQ A;  2FJM A;  3QCJ A;  2CNH A;  3AWF A;  2I1Y A;  3D1H A;  5EHR A;  3MMJ A;  1WCH A;  3MOW A;  4H34 A;  5KA3 A;  2NT7 A;  1ONZ A;  2J16 B;  2HVL A;  1LYV A;  2I6I A;  3F9B A;  2HC1 A;  2OOQ A;  3D1O A;  2HC2 A;  1L8G A;  1NZ7 A;  2OUD A;  2I6P A;  2QDM A;  1XXP A;  3ZMP A;  4QUM A;  3RO1 A;  2B4O A;  3QCM A;  4Y2E A;  3M4U A;  3V0G A;  4DGP A;  2CJZ A;  1PXH A;  3N0A A;  1L8K A;  2J17 A;  4GFU A;  1KAV A;  3QCN A;  2DXP A;  4RH9 A;  4QBW A;  1G4W R;  1T48 A;  2H02 A;  2BIJ A;  1NWL A;  4JMJ A;  3I36 A;  2E0T A;  3D42 A;  1G1H A;  4ICZ A;  2WGP A;  5K24 A;  1Q6T A;  1YN9 A;  2Q05 A;  4GE5 A;  2F6W A;  3S3H A;  3F9A A;  5K22 A;  1EEO A;  1C88 A;  2F6Z A;  1ZZW A;  4IKC A;  3SME A;  4GFV A;  2Y96 A;  1C84 A;  1OHE A;  5KA0 A;  4OHE A;  5KA7 A;  2OZ5 A;  1YZ4 A;  1WRM A;  2AZR A;  2BV5 A;  3BRH A;  1I9T A;  3EMU A;  4KI9 A;  2NT2 A;  1C83 A;  4WTY A;  2PA5 A;  4DGX A;  4MBB A;  2QDC A;  1XXV A;  2VEV A;  4AZ1 A;  5GTJ A;  1NNY A;  1YPT A;  2ESB A;  2I5X A;  1GWZ A;  2GP0 A;  4NND A;  3EB1 A;  1T49 A;  4QAH A;  3ZM2 A;  1BZC A;  3O4T A;  2M3V A;  1C87 A;  2QBQ A;  1KAK A;  5J8R A;  2Q47 A;  2CM2 A;  1OEO X;  1JF7 A;  3F99 A;  2AHS A;  4QAP A;  5IBM A;  3D1Q A;  2H03 A;  2VEW A;  3I80 A;  2PQ5 A;  5KAC A;  3QCK A;  1Q6P A;  4BPC A;  1YWF A;  4H1O A;  2CM8 A;  2VEX A;  3EU0 A;  2CNF A;  1G7F A;  4RHG A;  4OHL A;  3QCE A;  4ZN5 A;  3ZMQ A;  2C7S A;  2QBS A;  2B4P A;  2NZ6 A;  1X24 A;  5KAD A;  2NTA A;  1A5Y A;  2RF6 A;  1PYN A;  3H2X A;  1P15 A;  5K23 A;  4Z6B A;  4GWF A;  1RXD A;  1PTU A;  4PYH A;  3V0E A;  3QCL A;  1QXK A;  1ECV A;  1SUG A;  1WAX A;  4RH5 A;  3ZM0 A;  2BGD A;  3I7Z A;  2F70 A;  3CWE A;  2B07 A;  2HY3 A;  4NYH A;  4B04 A;  1J4X A;  1ZC0 A;  2J16 A;  3S3K A;  3S3F A;  2H4K A;  1OET A;  1AAX A;  1PTV A;  3V0D A;  1YTW A;  1PTY A;  4NWF A;  1OEV A;  1YTS A;  1Q6J A;  5KA1 A;  4OHI A;  2B4U A;  2F6V A;  3MOZ A;  2QBP A;  2HNP A;  3A5J A;  1G1F A;  1LQF A;  4JBC A;  1OES A;  3BLT A;  5KAB A;  3NME A;  4RKK A;  1GFY A;  2CMB A;  4YAA A;  4ZRT A;  3GXG A;  1RPM A;  3S4O A;  3QCF A;  4D3Q A;  4HRF A;  3D9C A;  3PS5 A;  1YFO A;  1FPZ A;  3O5X A;  1FQ1 A;  4WU2 A;  2CNG A;  1C85 A;  1U26 A; 
#chains in the Genus database with same CATH topology
 3QCD A;  5K9V A;  2Y68 A;  2CFV A;  2VEU A;  3HN7 A;  5KA8 A;  1P31 A;  4GE6 A;  1Q1M A;  2I3U A;  2FJN A;  2GC5 A;  2PT0 A;  2H4G A;  4QBE A;  5EHP A;  1FPR A;  1U24 A;  3BLU A;  2ZN7 A;  1YGR A;  3QKQ A;  2F6Y A;  1G4U S;  3AWG A;  1D5R A;  5M43 A;  2VTE A;  3V0F A;  2HXP A;  2G6Z A;  4ZIY A;  1R6H A;  5BZZ A;  5IBS A;  2I6O A;  5KA9 A;  2HB1 A;  2B4S A;  4ZI4 A;  2I4H A;  4HJQ A;  4HJP A;  2QCJ A;  4RI5 A;  3B7O A;  4JMK A;  3S3E A;  4CVL A;  2G59 A;  4TVV A;  3F81 A;  1OHD A;  1LAR A;  4WU3 A;  1NO6 A;  5KAA A;  2MBC A;  3QCG A;  3O4U A;  2SHP A;  3LJ8 A;  4Y14 A;  3ZV2 A;  2JFH A;  1E0D A;  2F6F A;  4GRZ A;  4UAG A;  4C13 A;  1U25 A;  2R0B A;  4J51 A;  4BUB A;  1UAG A;  1MKP A;  1YGU A;  2CM7 A;  2HCM A;  2VTD A;  3U96 A;  1PTT A;  1M3G A;  1JLN A;  2I4G A;  3O4S A;  2WTZ A;  3SR9 A;  3EZZ A;  4S0G A;  2H4V A;  1YTN A;  3D44 A;  4R30 A;  4D3P A;  2F6T A;  4R0S A;  2QDP A;  2I3R A;  2VEY A;  2ZMM A;  2NV5 A;  2I4E A;  1BZH A;  5BX1 A;  3CM3 A;  2P6X A;  2XJA A;  3QKP A;  3EAX A;  2CMA A;  4QUN A;  3V0H A;  2OC3 A;  1ONY A;  4BUC A;  2X5O A;  5BUG A;  5A5E A;  1Q6S A;  1PA9 A;  4RDD A;  2HNQ A;  5BZX A;  1I57 A;  2FH7 A;  4NX8 A;  2YDU A;  4YR8 B;  2CM3 A;  1E8C A;  1I9S A;  5LXQ B;  5MMZ B;  2WJP A;  5K25 A;  1OEM X;  3OLR A;  2I6J A;  1EEN A;  1VHR A;  2QEP A;  1T4J A;  4I8N A;  1QZ0 A;  1NL9 A;  3V0I A;  2CMC A;  1BZJ A;  4RI4 A;  2P4D A;  2PBN A;  2IMG A;  2QCT A;  1GQQ A;  2PSZ A;  2F46 A;  4GE2 A;  4PVG A;  4NWG A;  1Q6N A;  2NLK A;  1OHC A;  1PH0 A;  2A8B A;  5K9W A;  2PI7 A;  2F71 A;  2I6M A;  5KA2 A;  1OEU A;  3RGQ A;  2GWO A;  1PA1 A;  2I75 A;  3QCB A;  3AWE A;  4OHD A;  1V3A A;  2A3K A;  3V0J A;  2CNI A;  5KA4 A;  5A5F A;  2BGE A;  2VOS A;  2C46 A;  4OHH A;  1NWE A;  4GRY A;  3QCH A;  3ZM3 A;  2JJD A;  4GS0 A;  2H04 A;  1Q6M A;  1ZCK A;  4BJO A;  3RZ2 A;  2Y2F A;  3O3L A;  4D3R A;  4WOH A;  4R0T A;  3QCC A;  1JBW A;  1ZCL A;  3ZM1 A;  5I6V A;  2CNE A;  2VOR A;  2GJT A;  4KYR A;  2I42 A;  1G1G A;  3QCI A;  1XM2 A;  4JNB A;  1C86 A;  3A5K A;  3S4E A;  2B49 A;  2BZL A;  1XRI A;  3RGO A;  2QBR A;  3OMH A;  4ERC A;  5HDE A;  1XBO A;  1G7G A;  3BM8 A;  3F41 A;  1W7K A;  5AWX A;  3GXH A;  2B3O A;  4KYQ A;  2FJM A;  3QCJ A;  2CNH A;  3AWF A;  2I1Y A;  3D1H A;  5EHR A;  3MMJ A;  1WCH A;  3MOW A;  4H34 A;  5KA3 A;  2NT7 A;  1ONZ A;  2J16 B;  2HVL A;  1LYV A;  2I6I A;  3F9B A;  2HC1 A;  2OOQ A;  3D1O A;  4CVK A;  2HC2 A;  1L8G A;  2JFF A;  1NZ7 A;  2OUD A;  2I6P A;  2QDM A;  1XXP A;  2AM2 A;  4C12 A;  3ZMP A;  3QCZ A;  4QUM A;  3RO1 A;  2B4O A;  3QCM A;  4Y2E A;  3LK7 A;  3PYZ A;  3M4U A;  3V0G A;  4DGP A;  2Y67 A;  2CJZ A;  1PXH A;  3N0A A;  1L8K A;  2J17 A;  4GFU A;  1KAV A;  3QCN A;  1FGS A;  2DXP A;  4RH9 A;  4QBW A;  1G4W R;  1T48 A;  2H02 A;  2BIJ A;  1NWL A;  4JMJ A;  3I36 A;  2E0T A;  3D42 A;  1G1H A;  4ICZ A;  2WGP A;  4QF5 A;  1Q6T A;  5K24 A;  1YN9 A;  2Q05 A;  4GE5 A;  2F6W A;  3UAG A;  2GC6 A;  3S3H A;  3F9A A;  5K22 A;  1EEO A;  1C88 A;  2F6Z A;  1ZZW A;  4IKC A;  2Y1O A;  3SME A;  1GG4 A;  4GFV A;  2Y96 A;  1C84 A;  1OHE A;  5KA0 A;  4OHE A;  5KA7 A;  2OZ5 A;  1YZ4 A;  1WRM A;  1EEH A;  2AZR A;  3ZM5 A;  2BV5 A;  3BRH A;  1I9T A;  3EMU A;  4KI9 A;  2NT2 A;  1C83 A;  4WTY A;  2PA5 A;  2GCA A;  4DGX A;  4MBB A;  2QDC A;  1XXV A;  2VEV A;  4AZ1 A;  5GTJ A;  1NNY A;  1YPT A;  3MVN A;  2ESB A;  2I5X A;  1GWZ A;  3NRS A;  2GP0 A;  4NND A;  1P3D A;  3EB1 A;  1T49 A;  4QAH A;  3ZM2 A;  1BZC A;  3O4T A;  2M3V A;  1C87 A;  2QBQ A;  1J6U A;  1KAK A;  5J8R A;  2Q47 A;  2AM1 A;  2CM2 A;  1OEO X;  1JF7 A;  3F99 A;  2AHS A;  4QAP A;  5IBM A;  3D1Q A;  2H03 A;  2VEW A;  3I80 A;  2PQ5 A;  5KAC A;  3QCK A;  2UAG A;  4QDI A;  1Q6P A;  4BPC A;  1YWF A;  1GQY A;  4H1O A;  2CM8 A;  2VEX A;  3EU0 A;  2CNF A;  1G7F A;  2XPC A;  4RHG A;  4OHL A;  3QCE A;  4ZN5 A;  3ZMQ A;  3ZL8 A;  2C7S A;  2QBS A;  2B4P A;  3ZM6 A;  2NZ6 A;  1W78 A;  1X24 A;  5KAD A;  2NTA A;  1A5Y A;  2RF6 A;  1PYN A;  3H2X A;  1P15 A;  2GCB A;  4CVM A;  5K23 A;  4Z6B A;  2JFG A;  4GWF A;  1RXD A;  1PTU A;  4PYH A;  3V0E A;  3QCL A;  1QXK A;  1ECV A;  1SUG A;  1WAX A;  4RH5 A;  3ZM0 A;  2BGD A;  3I7Z A;  2F70 A;  3CWE A;  2B07 A;  2HY3 A;  4NYH A;  4HV4 A;  4B04 A;  1J4X A;  1ZC0 A;  2J16 A;  3S3K A;  3S3F A;  2H4K A;  2Y66 A;  1OET A;  1AAX A;  1PTV A;  3V0D A;  1YTW A;  1PTY A;  4NWF A;  1OEV A;  1YTS A;  1Q6J A;  5KA1 A;  4OHI A;  2B4U A;  2F6V A;  3MOZ A;  2F00 A;  2QBP A;  1O5Z A;  2HNP A;  3A5J A;  1G1F A;  2UUO A;  1LQF A;  4JBC A;  1OES A;  3BLT A;  2UUP A;  1JBV A;  3NME A;  5KAB A;  4RKK A;  1GFY A;  2CMB A;  4YAA A;  4ZRT A;  3GXG A;  1RPM A;  3S4O A;  3QCF A;  4D3Q A;  4HRF A;  3D9C A;  3N2A A;  3PS5 A;  1YFO A;  1FPZ A;  3O5X A;  1FQ1 A;  4WU2 A;  2CNG A;  1C85 A;  1U26 A; 
#chains in the Genus database with same CATH homology
 3QCD A;  5K9V A;  2CFV A;  2VEU A;  5KA8 A;  4GE6 A;  1Q1M A;  2I3U A;  2FJN A;  2PT0 A;  2H4G A;  4QBE A;  5EHP A;  1FPR A;  1U24 A;  3BLU A;  2ZN7 A;  1YGR A;  3QKQ A;  2F6Y A;  1G4U S;  3AWG A;  1D5R A;  5M43 A;  3V0F A;  2HXP A;  2G6Z A;  1R6H A;  5BZZ A;  5IBS A;  2I6O A;  5KA9 A;  2HB1 A;  2B4S A;  4ZI4 A;  2I4H A;  4HJQ A;  4HJP A;  2QCJ A;  4RI5 A;  3B7O A;  4JMK A;  3S3E A;  2G59 A;  4TVV A;  3F81 A;  1OHD A;  1LAR A;  4WU3 A;  1NO6 A;  5KAA A;  2MBC A;  3QCG A;  3O4U A;  2SHP A;  3LJ8 A;  4Y14 A;  3ZV2 A;  2F6F A;  4GRZ A;  1U25 A;  2R0B A;  4J51 A;  1YGU A;  1MKP A;  2CM7 A;  2HCM A;  3U96 A;  1PTT A;  1M3G A;  1JLN A;  2I4G A;  3O4S A;  3SR9 A;  3EZZ A;  4S0G A;  2H4V A;  1YTN A;  3D44 A;  4R30 A;  4D3P A;  2F6T A;  4R0S A;  2QDP A;  2I3R A;  2VEY A;  2ZMM A;  2NV5 A;  2I4E A;  1BZH A;  5BX1 A;  3CM3 A;  2P6X A;  3QKP A;  3EAX A;  2CMA A;  4QUN A;  3V0H A;  2OC3 A;  1ONY A;  5BUG A;  1Q6S A;  1PA9 A;  4RDD A;  2HNQ A;  5BZX A;  1I57 A;  2FH7 A;  4NX8 A;  2YDU A;  4YR8 B;  2CM3 A;  1I9S A;  5LXQ B;  5MMZ B;  5K25 A;  1OEM X;  3OLR A;  2I6J A;  1EEN A;  1VHR A;  2QEP A;  1T4J A;  4I8N A;  1QZ0 A;  1NL9 A;  3V0I A;  2CMC A;  1BZJ A;  4RI4 A;  2P4D A;  2PBN A;  2IMG A;  2QCT A;  2PSZ A;  2F46 A;  4GE2 A;  4PVG A;  4NWG A;  1Q6N A;  2NLK A;  1OHC A;  1PH0 A;  2A8B A;  5K9W A;  2PI7 A;  2F71 A;  2I6M A;  5KA2 A;  1OEU A;  3RGQ A;  2GWO A;  1PA1 A;  2I75 A;  3QCB A;  3AWE A;  4OHD A;  1V3A A;  2A3K A;  3V0J A;  2CNI A;  5KA4 A;  2BGE A;  2C46 A;  4OHH A;  1NWE A;  4GRY A;  3QCH A;  3ZM3 A;  2JJD A;  4GS0 A;  2H04 A;  1Q6M A;  1ZCK A;  4BJO A;  3RZ2 A;  2Y2F A;  3O3L A;  4D3R A;  4WOH A;  4R0T A;  3QCC A;  3ZM1 A;  1ZCL A;  5I6V A;  2CNE A;  2GJT A;  4KYR A;  2I42 A;  1G1G A;  3QCI A;  1XM2 A;  4JNB A;  1C86 A;  3A5K A;  3S4E A;  2B49 A;  2BZL A;  1XRI A;  3RGO A;  2QBR A;  3OMH A;  4ERC A;  5HDE A;  1XBO A;  1G7G A;  3BM8 A;  3F41 A;  5AWX A;  3GXH A;  2B3O A;  4KYQ A;  2FJM A;  3QCJ A;  2CNH A;  3AWF A;  2I1Y A;  3D1H A;  5EHR A;  3MMJ A;  1WCH A;  3MOW A;  4H34 A;  5KA3 A;  2NT7 A;  1ONZ A;  2J16 B;  2HVL A;  1LYV A;  2I6I A;  3F9B A;  2HC1 A;  2OOQ A;  3D1O A;  2HC2 A;  1L8G A;  1NZ7 A;  2OUD A;  2I6P A;  2QDM A;  1XXP A;  3ZMP A;  4QUM A;  3RO1 A;  2B4O A;  3QCM A;  4Y2E A;  3M4U A;  3V0G A;  4DGP A;  2CJZ A;  1PXH A;  3N0A A;  1L8K A;  2J17 A;  4GFU A;  1KAV A;  3QCN A;  2DXP A;  4RH9 A;  4QBW A;  1G4W R;  1T48 A;  2H02 A;  2BIJ A;  1NWL A;  4JMJ A;  3I36 A;  2E0T A;  3D42 A;  1G1H A;  4ICZ A;  2WGP A;  5K24 A;  1Q6T A;  1YN9 A;  2Q05 A;  4GE5 A;  2F6W A;  3S3H A;  3F9A A;  5K22 A;  1EEO A;  1C88 A;  2F6Z A;  1ZZW A;  4IKC A;  3SME A;  4GFV A;  2Y96 A;  1C84 A;  1OHE A;  5KA0 A;  4OHE A;  5KA7 A;  2OZ5 A;  1YZ4 A;  1WRM A;  2AZR A;  2BV5 A;  3BRH A;  1I9T A;  3EMU A;  4KI9 A;  2NT2 A;  1C83 A;  4WTY A;  2PA5 A;  4DGX A;  4MBB A;  2QDC A;  1XXV A;  2VEV A;  4AZ1 A;  5GTJ A;  1NNY A;  1YPT A;  2ESB A;  2I5X A;  1GWZ A;  2GP0 A;  4NND A;  3EB1 A;  1T49 A;  4QAH A;  3ZM2 A;  1BZC A;  3O4T A;  2M3V A;  1C87 A;  2QBQ A;  1KAK A;  5J8R A;  2Q47 A;  2CM2 A;  1OEO X;  1JF7 A;  3F99 A;  2AHS A;  4QAP A;  5IBM A;  3D1Q A;  2H03 A;  2VEW A;  3I80 A;  2PQ5 A;  5KAC A;  3QCK A;  1Q6P A;  4BPC A;  1YWF A;  4H1O A;  2CM8 A;  2VEX A;  3EU0 A;  2CNF A;  1G7F A;  4RHG A;  4OHL A;  3QCE A;  4ZN5 A;  3ZMQ A;  2C7S A;  2QBS A;  2B4P A;  2NZ6 A;  1X24 A;  5KAD A;  2NTA A;  1A5Y A;  2RF6 A;  1PYN A;  3H2X A;  1P15 A;  5K23 A;  4Z6B A;  4GWF A;  1RXD A;  1PTU A;  4PYH A;  3V0E A;  3QCL A;  1QXK A;  1ECV A;  1SUG A;  1WAX A;  4RH5 A;  3ZM0 A;  2BGD A;  3I7Z A;  2F70 A;  3CWE A;  2B07 A;  2HY3 A;  4NYH A;  4B04 A;  1J4X A;  1ZC0 A;  2J16 A;  3S3K A;  3S3F A;  2H4K A;  1OET A;  1AAX A;  1PTV A;  3V0D A;  1YTW A;  1PTY A;  4NWF A;  1OEV A;  1YTS A;  1Q6J A;  5KA1 A;  4OHI A;  2B4U A;  2F6V A;  3MOZ A;  2QBP A;  2HNP A;  3A5J A;  1G1F A;  1LQF A;  4JBC A;  1OES A;  3BLT A;  5KAB A;  3NME A;  4RKK A;  1GFY A;  2CMB A;  4YAA A;  4ZRT A;  3GXG A;  1RPM A;  3S4O A;  3QCF A;  4D3Q A;  4HRF A;  3D9C A;  3PS5 A;  1YFO A;  1FPZ A;  3O5X A;  1FQ1 A;  4WU2 A;  2CNG A;  1C85 A;  1U26 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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