2A3ZB

Ternary complex of the wh2 domain of wasp with actin-dnase i
Total Genus 93
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
93
sequence length
260
structure length
260
Chain Sequence
LKIAAFNIRTFGETKMSNATLASYIVRIVRRYDIVLIQEVRDSHLVAVGKLLDYLNQDDPNTYHYVVSEPLGRNSYKERYLFLFRPNKVSVLDTYQYDDGCESCGNDSFSREPAVVKFSSHSTKVKEFAIVALHSAPSDAVAEINSLYDVYLDVQQKWHLNDVMLMGDFNADCSYVTSSQWSSIRLRTSSTFQWLIPDSADTTATSTNCAYDRIVVAGSLLQSSVVPGSAAPFDFQAAYGLSNEMALAISDHYPVEVTLT
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Actin-bound structures of Wiskott-Aldrich syndrome protein (WASP)-homology domain 2 and the implications for filament assembly
pubmed doi rcsb
molecule tags Structural protein
molecule keywords Actin, alpha skeletal muscle
total genus 93
structure length 260
sequence length 260
ec nomenclature ec 3.1.21.1: Deoxyribonuclease I.
pdb deposition date 2005-06-27

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF03372 Exo_endo_phos Endonuclease/Exonuclease/phosphatase family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.60.10.10 Alpha Beta 4-Layer Sandwich Deoxyribonuclease I; Chain A Endonuclease/exonuclease/phosphatase 2a3zB00
2A42B 3W3DB 2DDSA 3U8UA 1YJHA 3G00A 4F1RA 1I9ZA 2JC4A 5INLA 5DFFA 3G38A 3TEBA 5J42A 1DE9A 4L1YA 5INMA 3GA6A 4QH9A 1ZWXA 1AKOA 2DDRA 2DNJA 3I46A 5DFHA 3NGOA 5INOA 4FPVA 3G0AA 3K55A 2VOAA 1DE8A 1BIXA 5EWTA 1SR4B 4C1RA 1HD7A 1VYBA 3N9VA 4GEWA 5J3ZA 3WCXA 4L1ZA 2F2FB 5J3PA 3W2YA 3I48A 5DG0A 5INPA 4B5GA 4B5HA 1DNKA 3G2DA 3MTCA 3G4TA 4GZ0A 2V0SA 1Y21A 4F1HB 3W2XA 5INQA 5A7JA 2ISIA 4GZ1A 5DV4A 5J8NA 4B5JA 3G91A 5A7IA 2O3CA 3G1KA 4CMLA 5INKA 4AWNA 2A3ZB 5DV2A 3FZIA 2DDTA 5HT2A 2UYRX 5CFEA 1ATND 4L20A 5DFIA 4B5MA 3G2CA 2IMQX 4B5IA 3NGNA 2JC5A 2A40B 4JG3A 3G3CA 3MPRA 3G3YA 4QHDA 2J63A 3NR8A 2O3HA 1I9YA 4PUQA 4F1IA 1DEWA 1NTFA 3G8VA 2F1NA 1SI6X 4QHEA 2V0RA 5CFGA 4GYZA 4CMNA 5INNA 4L21A 4K6LF 3I5VA 2D1KB 3I41A 1WDUA 2XSWA 3G6SA 4LNDA 3G0RA 2A41B 4B5FA 3DNIA 3NGQA 4F1HA 4A9CA 4GZ2A 4RUWA 5DFJA 4FVAA 4IEMA 2EI9A 3L1WA 3CJCD 1E9NA 5J3SA
chains in the Genus database with same CATH superfamily
2A42B 3W3DB 2DDSA 3U8UA 1YJHA 3G00A 4F1RA 1I9ZA 2JC4A 5INLA 5DFFA 3G38A 3TEBA 5J42A 1DE9A 4L1YA 5INMA 3GA6A 4QH9A 1ZWXA 1AKOA 2DDRA 2DNJA 3I46A 5DFHA 3NGOA 5INOA 4FPVA 3G0AA 3K55A 2VOAA 1DE8A 1BIXA 5EWTA 1SR4B 4C1RA 1HD7A 1VYBA 3N9VA 4GEWA 5J3ZA 3WCXA 4L1ZA 2F2FB 5J3PA 3W2YA 3I48A 5DG0A 5INPA 4B5GA 4B5HA 1DNKA 3G2DA 3MTCA 3G4TA 4GZ0A 2V0SA 1Y21A 4F1HB 3W2XA 5INQA 5A7JA 2ISIA 4GZ1A 5DV4A 5J8NA 4B5JA 3G91A 5A7IA 2O3CA 3G1KA 4CMLA 5INKA 4AWNA 2A3ZB 5DV2A 3FZIA 2DDTA 5HT2A 2UYRX 5CFEA 1ATND 4L20A 5DFIA 4B5MA 3G2CA 2IMQX 4B5IA 3NGNA 2JC5A 2A40B 4JG3A 3G3CA 3MPRA 3G3YA 4QHDA 2J63A 3NR8A 2O3HA 1I9YA 4PUQA 4F1IA 1DEWA 1NTFA 3G8VA 2F1NA 1SI6X 4QHEA 2V0RA 5CFGA 4GYZA 4CMNA 5INNA 4L21A 4K6LF 3I5VA 2D1KB 3I41A 1WDUA 2XSWA 3G6SA 4LNDA 3G0RA 2A41B 4B5FA 3DNIA 3NGQA 4F1HA 4A9CA 4GZ2A 4RUWA 5DFJA 4FVAA 4IEMA 2EI9A 3L1WA 3CJCD 1E9NA 5J3SA
chains in the Genus database with same CATH topology
2A42B 3W3DB 2DDSA 3U8UA 1YJHA 3G00A 4F1RA 1I9ZA 2JC4A 5INLA 5DFFA 3G38A 3TEBA 5J42A 1DE9A 4L1YA 5INMA 3GA6A 4QH9A 1ZWXA 1AKOA 2DDRA 2DNJA 3I46A 5DFHA 3NGOA 5INOA 4FPVA 3G0AA 3K55A 2VOAA 1DE8A 1BIXA 5EWTA 1SR4B 4C1RA 1HD7A 1VYBA 3N9VA 4GEWA 5J3ZA 3WCXA 4L1ZA 2F2FB 5J3PA 3W2YA 3I48A 5DG0A 5INPA 4B5GA 4B5HA 1DNKA 3G2DA 3MTCA 3G4TA 4GZ0A 2V0SA 1Y21A 4F1HB 3W2XA 5INQA 5A7JA 2ISIA 4GZ1A 5DV4A 5J8NA 4B5JA 3G91A 5A7IA 2O3CA 3G1KA 4CMLA 5INKA 4AWNA 2A3ZB 5DV2A 3FZIA 2DDTA 5HT2A 2UYRX 5CFEA 1ATND 4L20A 5DFIA 4B5MA 3G2CA 2IMQX 4B5IA 3NGNA 2JC5A 2A40B 4JG3A 3G3CA 3MPRA 3G3YA 4QHDA 2J63A 3NR8A 2O3HA 1I9YA 4PUQA 4F1IA 1DEWA 1NTFA 3G8VA 2F1NA 1SI6X 4QHEA 2V0RA 5CFGA 4GYZA 4CMNA 5INNA 4L21A 4K6LF 3I5VA 2D1KB 3I41A 1WDUA 2XSWA 3G6SA 4LNDA 3G0RA 2A41B 4B5FA 3DNIA 3NGQA 4F1HA 4A9CA 4GZ2A 4RUWA 5DFJA 4FVAA 4IEMA 2EI9A 3L1WA 3CJCD 1E9NA 5J3SA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2A42 B;  3W3D B;  2DDS A;  3U8U A;  1YJH A;  3G00 A;  4F1R A;  1I9Z A;  2JC4 A;  5INL A;  5DFF A;  3G38 A;  3TEB A;  5J42 A;  1DE9 A;  4L1Y A;  5INM A;  3GA6 A;  4QH9 A;  1ZWX A;  1AKO A;  2DDR A;  2DNJ A;  3I46 A;  5DFH A;  3NGO A;  5INO A;  4FPV A;  3G0A A;  3K55 A;  2VOA A;  1DE8 A;  1BIX A;  5EWT A;  1SR4 B;  4C1R A;  1HD7 A;  1VYB A;  3N9V A;  4GEW A;  5J3Z A;  3WCX A;  4L1Z A;  2F2F B;  5J3P A;  3W2Y A;  3I48 A;  5DG0 A;  5INP A;  4B5G A;  4B5H A;  1DNK A;  3G2D A;  3MTC A;  3G4T A;  4GZ0 A;  2V0S A;  1Y21 A;  4F1H B;  3W2X A;  5INQ A;  5A7J A;  2ISI A;  4GZ1 A;  5DV4 A;  5J8N A;  4B5J A;  3G91 A;  5A7I A;  2O3C A;  3G1K A;  4CML A;  5INK A;  4AWN A;  2A3Z B;  5DV2 A;  3FZI A;  2DDT A;  5HT2 A;  2UYR X;  5CFE A;  1ATN D;  4L20 A;  5DFI A;  4B5M A;  3G2C A;  2IMQ X;  4B5I A;  3NGN A;  2JC5 A;  2A40 B;  4JG3 A;  3G3C A;  3MPR A;  3G3Y A;  4QHD A;  2J63 A;  3NR8 A;  2O3H A;  1I9Y A;  4PUQ A;  4F1I A;  1DEW A;  1NTF A;  3G8V A;  2F1N A;  1SI6 X;  4QHE A;  2V0R A;  5CFG A;  4GYZ A;  4CMN A;  5INN A;  4L21 A;  4K6L F;  3I5V A;  2D1K B;  3I41 A;  1WDU A;  2XSW A;  3G6S A;  4LND A;  3G0R A;  2A41 B;  4B5F A;  3DNI A;  3NGQ A;  4F1H A;  4A9C A;  4GZ2 A;  4RUW A;  5DFJ A;  4FVA A;  4IEM A;  2EI9 A;  3L1W A;  3CJC D;  1E9N A;  5J3S A; 
#chains in the Genus database with same CATH topology
 2A42 B;  3W3D B;  2DDS A;  3U8U A;  1YJH A;  3G00 A;  4F1R A;  1I9Z A;  2JC4 A;  5INL A;  5DFF A;  3G38 A;  3TEB A;  5J42 A;  1DE9 A;  4L1Y A;  5INM A;  3GA6 A;  4QH9 A;  1ZWX A;  1AKO A;  2DDR A;  2DNJ A;  3I46 A;  5DFH A;  3NGO A;  5INO A;  4FPV A;  3G0A A;  3K55 A;  2VOA A;  1DE8 A;  1BIX A;  5EWT A;  1SR4 B;  4C1R A;  1HD7 A;  1VYB A;  3N9V A;  4GEW A;  5J3Z A;  3WCX A;  4L1Z A;  2F2F B;  5J3P A;  3W2Y A;  3I48 A;  5DG0 A;  5INP A;  4B5G A;  4B5H A;  1DNK A;  3G2D A;  3MTC A;  3G4T A;  4GZ0 A;  2V0S A;  1Y21 A;  4F1H B;  3W2X A;  5INQ A;  5A7J A;  2ISI A;  4GZ1 A;  5DV4 A;  5J8N A;  4B5J A;  3G91 A;  5A7I A;  2O3C A;  3G1K A;  4CML A;  5INK A;  4AWN A;  2A3Z B;  5DV2 A;  3FZI A;  2DDT A;  5HT2 A;  2UYR X;  5CFE A;  1ATN D;  4L20 A;  5DFI A;  4B5M A;  3G2C A;  2IMQ X;  4B5I A;  3NGN A;  2JC5 A;  2A40 B;  4JG3 A;  3G3C A;  3MPR A;  3G3Y A;  4QHD A;  2J63 A;  3NR8 A;  2O3H A;  1I9Y A;  4PUQ A;  4F1I A;  1DEW A;  1NTF A;  3G8V A;  2F1N A;  1SI6 X;  4QHE A;  2V0R A;  5CFG A;  4GYZ A;  4CMN A;  5INN A;  4L21 A;  4K6L F;  3I5V A;  2D1K B;  3I41 A;  1WDU A;  2XSW A;  3G6S A;  4LND A;  3G0R A;  2A41 B;  4B5F A;  3DNI A;  3NGQ A;  4F1H A;  4A9C A;  4GZ2 A;  4RUW A;  5DFJ A;  4FVA A;  4IEM A;  2EI9 A;  3L1W A;  3CJC D;  1E9N A;  5J3S A; 
#chains in the Genus database with same CATH homology
 2A42 B;  3W3D B;  2DDS A;  3U8U A;  1YJH A;  3G00 A;  4F1R A;  1I9Z A;  2JC4 A;  5INL A;  5DFF A;  3G38 A;  3TEB A;  5J42 A;  1DE9 A;  4L1Y A;  5INM A;  3GA6 A;  4QH9 A;  1ZWX A;  1AKO A;  2DDR A;  2DNJ A;  3I46 A;  5DFH A;  3NGO A;  5INO A;  4FPV A;  3G0A A;  3K55 A;  2VOA A;  1DE8 A;  1BIX A;  5EWT A;  1SR4 B;  4C1R A;  1HD7 A;  1VYB A;  3N9V A;  4GEW A;  5J3Z A;  3WCX A;  4L1Z A;  2F2F B;  5J3P A;  3W2Y A;  3I48 A;  5DG0 A;  5INP A;  4B5G A;  4B5H A;  1DNK A;  3G2D A;  3MTC A;  3G4T A;  4GZ0 A;  2V0S A;  1Y21 A;  4F1H B;  3W2X A;  5INQ A;  5A7J A;  2ISI A;  4GZ1 A;  5DV4 A;  5J8N A;  4B5J A;  3G91 A;  5A7I A;  2O3C A;  3G1K A;  4CML A;  5INK A;  4AWN A;  2A3Z B;  5DV2 A;  3FZI A;  2DDT A;  5HT2 A;  2UYR X;  5CFE A;  1ATN D;  4L20 A;  5DFI A;  4B5M A;  3G2C A;  2IMQ X;  4B5I A;  3NGN A;  2JC5 A;  2A40 B;  4JG3 A;  3G3C A;  3MPR A;  3G3Y A;  4QHD A;  2J63 A;  3NR8 A;  2O3H A;  1I9Y A;  4PUQ A;  4F1I A;  1DEW A;  1NTF A;  3G8V A;  2F1N A;  1SI6 X;  4QHE A;  2V0R A;  5CFG A;  4GYZ A;  4CMN A;  5INN A;  4L21 A;  4K6L F;  3I5V A;  2D1K B;  3I41 A;  1WDU A;  2XSW A;  3G6S A;  4LND A;  3G0R A;  2A41 B;  4B5F A;  3DNI A;  3NGQ A;  4F1H A;  4A9C A;  4GZ2 A;  4RUW A;  5DFJ A;  4FVA A;  4IEM A;  2EI9 A;  3L1W A;  3CJC D;  1E9N A;  5J3S A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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