2ABXA

The crystal structure of alpha-bungarotoxin at 2.5 angstroms resolution. relation to solution structure and binding to acetylcholine receptor
Total Genus 5
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
5
sequence length
74
structure length
74
Chain Sequence
IVCHTTATIPSSAVTCPPGENLCYRKMWCDAFCSSRGKVVELGCAATCPSKKPYEEVTCCSTDKCNHPPKRQPG
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The crystal structure of alpha-bungarotoxin at 2.5 A resolution: relation to solution structure and binding to acetylcholine receptor.
pubmed doi rcsb
molecule keywords ALPHA-BUNGAROTOXIN
molecule tags Postsynaptic neurotoxin
source organism Bungarus multicinctus
total genus 5
structure length 74
sequence length 74
chains with identical sequence B
ec nomenclature
pdb deposition date 1986-02-19

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00087 Toxin_TOLIP Snake toxin and toxin-like protein
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.10.60.10 Mainly Beta Ribbon CD59 CD59 2abxA00
1REWC 2FD6U 1XT3A 1FSSB 3PLCA 2CTXA 5DU1A 1KBAA 3KFDE 1IJCA 2JQPA 1NORA 1CDTA 1ERAA 2J8BA 1FFJA 2L5SA 1F94A 1W6BA 1G6MA 4QTIU 3LAQU 1TFSA 1CVOA 1QM7A 1TXBA 5DO6A 1YWHA 1BXPA 2NBTA 1CDQA 2GOOB 4ZQYA 2N99A 2QJBC 4LFTA 5IMYC 1NEAA 2MUPA 1CB9A 2H62D 2MJYA 2CRTA 1F8UB 2QJAC 1HC9B 1B41B 2H5FA 1HOYA 4FAOC 1CXNA 1V6PA 1CREA 2CDXA 2UX2A 4BIKB 1KXIA 2L03A 3NDSA 2ERAA 1CRFA 2BHIA 1DRSA 1KU6B 1CTXA 3U73U 1JBDA 1M9ZA 3BT2U 1ES7B 1COEA 1LX5B 1JGKA 1KBTA 1HAAA 2LA1A 2MJ4A 4EY8B 2H62C 2PJYB 2JVEA 1LSIA 4FAOE 1NYUA 1MR6A 1KC4A 2UWRA 1RGJA 2BTXA 4UY2C 3EVSC 1IQ9A 2MFAA 1FASA 2OFSA 1HAJA 5EBXA 4BDTB 1ONJA 4P7UA 4AEAA 4XJJA 1KTZB 1RL5A 3U74U 2H7ZB 4HQPF 1S4YA 2H8UA 1I02A 1ZADA 2K3GA 2LCRA 1NTXA 1CHVS 4RUDA 1HC9A 1JE9A 1KBSA 2MJ0A 1KS6A 1IDGA 2H64C 1QKDA 3ERAA 1CCQA 5DZ5A 2X8BB 1MAHF 2H7ZA 2GOOC 1KFHA 3VTSA 1KL8A 2QC1A 3QB4B 4OM4A 1UG4A 2CCXA 3NEQA 1L4WA 1PLOA 1TXAA 3EBXA 3FEVA 1FF4A 1NYSA 1QKEA 1LXGA 2HLQA 2H64B 1CXOA 2CRSA 3KFDI 1CODA 1IDLA 1IDHA 4DO8A 1VB0A 1FSCA 1IK8A 1ERGA 1IDIA 3HH7A 1H0JA 1CDSA 1ABTA 1FRAA 4OM5A 1CDRA 3NH7A 1BTEA 1NTNA 1TGXA 2ABXA 2MHYA 3BT1U 4IYEA 2I9BE 2PJYC 2QJ9C 2HLRA 2VLWA 6EBXA 1NXBA 2MUOA 1LXHA 1LJZA 5IMTD 1IKCA
chains in the Genus database with same CATH superfamily
1REWC 2FD6U 1XT3A 1FSSB 3PLCA 2CTXA 4KSNA 5DU1A 1KBAA 3KFDE 1IJCA 2JQPA 1NORA 1CDTA 1ERAA 2J8BA 1FFJA 2L5SA 1F94A 1W6BA 1G6MA 4QTIU 3LAQU 1TFSA 1CVOA 1QM7A 1TXBA 5DO6A 1YWHA 1BXPA 2NBTA 1CDQA 2GOOB 4ZQYA 2N99A 2QJBC 4LFTA 5IMYC 1NEAA 2MUPA 1CB9A 2H62D 2MJYA 2CRTA 1F8UB 2QJAC 1HC9B 1B41B 2H5FA 1HOYA 4FAOC 1CXNA 1V6PA 1CREA 2CDXA 2UX2A 4BIKB 1KXIA 2L03A 3NDSA 2ERAA 1CRFA 2BHIA 1DRSA 1KU6B 1CTXA 3U73U 1JBDA 1M9ZA 3BT2U 1ES7B 1COEA 1LX5B 1JGKA 1KBTA 1HAAA 2LA1A 2MJ4A 4EY8B 2H62C 2PJYB 2JVEA 1LSIA 4FAOE 1NYUA 1MR6A 1KC4A 2UWRA 1RGJA 2BTXA 4UY2C 3EVSC 1IQ9A 2MFAA 1FASA 2OFSA 1HAJA 5EBXA 4BDTB 1ONJA 4P7UA 4AEAA 4XJJA 1KTZB 1RL5A 3U74U 2H7ZB 4HQPF 1S4YA 2H8UA 1I02A 1ZADA 2K3GA 2LCRA 1NTXA 1CHVS 4RUDA 1HC9A 1JE9A 1KBSA 2MJ0A 1KS6A 1IDGA 2H64C 1QKDA 3ERAA 1CCQA 5DZ5A 2X8BB 1MAHF 2H7ZA 2GOOC 1KFHA 3VTSA 1KL8A 2QC1A 3QB4B 4OM4A 1UG4A 2CCXA 3NEQA 1L4WA 1PLOA 1TXAA 3EBXA 3FEVA 1FF4A 1NYSA 1QKEA 1LXGA 2HLQA 2H64B 1CXOA 2CRSA 3KFDI 1CODA 1IDLA 1IDHA 4DO8A 1VB0A 1FSCA 1IK8A 1ERGA 1IDIA 3HH7A 1H0JA 1CDSA 1ABTA 1FRAA 4OM5A 1CDRA 3NH7A 1BTEA 1NTNA 1TGXA 2ABXA 2MHYA 3BT1U 4IYEA 2I9BE 2PJYC 2QJ9C 2HLRA 2VLWA 6EBXA 1NXBA 2MUOA 1LXHA 1LJZA 5IMTD 1IKCA
chains in the Genus database with same CATH topology
1REWC 2FD6U 1XT3A 1FSSB 3PLCA 2CTXA 4KSNA 5DU1A 1KBAA 3KFDE 1IJCA 2JQPA 1NORA 1CDTA 1ERAA 2J8BA 1FFJA 2L5SA 1F94A 1W6BA 1G6MA 4QTIU 3LAQU 1TFSA 1CVOA 1QM7A 1TXBA 5DO6A 1YWHA 1BXPA 2NBTA 1CDQA 2GOOB 4ZQYA 2N99A 2QJBC 4LFTA 5IMYC 1NEAA 2MUPA 1CB9A 2H62D 2MJYA 2CRTA 1F8UB 2QJAC 1HC9B 1B41B 2H5FA 1HOYA 4FAOC 1CXNA 1V6PA 1CREA 2CDXA 2UX2A 4BIKB 1KXIA 2L03A 3NDSA 2ERAA 1CRFA 2BHIA 1DRSA 1KU6B 1CTXA 3U73U 1JBDA 1M9ZA 3BT2U 1ES7B 1COEA 1LX5B 1JGKA 1KBTA 1HAAA 2LA1A 2MJ4A 4EY8B 2H62C 2PJYB 2JVEA 1LSIA 4FAOE 1NYUA 1MR6A 1KC4A 2UWRA 1RGJA 2BTXA 4UY2C 3EVSC 1IQ9A 2MFAA 1FASA 2OFSA 1HAJA 5EBXA 4BDTB 1ONJA 4P7UA 4AEAA 4XJJA 1KTZB 1RL5A 3U74U 2H7ZB 4HQPF 1S4YA 2H8UA 1I02A 1ZADA 2K3GA 2LCRA 1NTXA 1CHVS 4RUDA 1HC9A 1JE9A 1KBSA 2MJ0A 1KS6A 1IDGA 2H64C 1QKDA 3ERAA 1CCQA 5DZ5A 2X8BB 1MAHF 2H7ZA 2GOOC 1KFHA 3VTSA 1KL8A 2QC1A 3QB4B 4OM4A 1UG4A 2CCXA 3NEQA 1L4WA 1PLOA 1TXAA 3EBXA 3FEVA 1FF4A 1NYSA 1QKEA 1LXGA 2HLQA 2H64B 1CXOA 2CRSA 3KFDI 1CODA 1IDLA 1IDHA 4DO8A 1VB0A 1FSCA 1IK8A 1ERGA 1IDIA 3HH7A 1H0JA 1CDSA 1ABTA 1FRAA 4OM5A 1CDRA 3NH7A 1BTEA 1NTNA 1TGXA 2ABXA 2MHYA 3BT1U 4IYEA 2I9BE 2PJYC 2QJ9C 2HLRA 2VLWA 6EBXA 1NXBA 2MUOA 1LXHA 1LJZA 5IMTD 1IKCA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1REW C;  2FD6 U;  1XT3 A;  1FSS B;  3PLC A;  2CTX A;  5DU1 A;  1KBA A;  3KFD E;  1IJC A;  2JQP A;  1NOR A;  1CDT A;  1ERA A;  2J8B A;  1FFJ A;  2L5S A;  1F94 A;  1W6B A;  1G6M A;  4QTI U;  3LAQ U;  1TFS A;  1CVO A;  1QM7 A;  1TXB A;  5DO6 A;  1YWH A;  1BXP A;  2NBT A;  1CDQ A;  2GOO B;  4ZQY A;  2N99 A;  2QJB C;  4LFT A;  5IMY C;  1NEA A;  2MUP A;  1CB9 A;  2H62 D;  2MJY A;  2CRT A;  1F8U B;  2QJA C;  1HC9 B;  1B41 B;  2H5F A;  1HOY A;  4FAO C;  1CXN A;  1V6P A;  1CRE A;  2CDX A;  2UX2 A;  4BIK B;  1KXI A;  2L03 A;  3NDS A;  2ERA A;  1CRF A;  2BHI A;  1DRS A;  1KU6 B;  1CTX A;  3U73 U;  1JBD A;  1M9Z A;  3BT2 U;  1ES7 B;  1COE A;  1LX5 B;  1JGK A;  1KBT A;  1HAA A;  2LA1 A;  2MJ4 A;  4EY8 B;  2H62 C;  2PJY B;  2JVE A;  1LSI A;  4FAO E;  1NYU A;  1MR6 A;  1KC4 A;  2UWR A;  1RGJ A;  2BTX A;  4UY2 C;  3EVS C;  1IQ9 A;  2MFA A;  1FAS A;  2OFS A;  1HAJ A;  5EBX A;  4BDT B;  1ONJ A;  4P7U A;  4AEA A;  4XJJ A;  1KTZ B;  1RL5 A;  3U74 U;  2H7Z B;  4HQP F;  1S4Y A;  2H8U A;  1I02 A;  1ZAD A;  2K3G A;  2LCR A;  1NTX A;  1CHV S;  4RUD A;  1HC9 A;  1JE9 A;  1KBS A;  2MJ0 A;  1KS6 A;  1IDG A;  2H64 C;  1QKD A;  3ERA A;  1CCQ A;  5DZ5 A;  2X8B B;  1MAH F;  2H7Z A;  2GOO C;  1KFH A;  3VTS A;  1KL8 A;  2QC1 A;  3QB4 B;  4OM4 A;  1UG4 A;  2CCX A;  3NEQ A;  1L4W A;  1PLO A;  1TXA A;  3EBX A;  3FEV A;  1FF4 A;  1NYS A;  1QKE A;  1LXG A;  2HLQ A;  2H64 B;  1CXO A;  2CRS A;  3KFD I;  1COD A;  1IDL A;  1IDH A;  4DO8 A;  1VB0 A;  1FSC A;  1IK8 A;  1ERG A;  1IDI A;  3HH7 A;  1H0J A;  1CDS A;  1ABT A;  1FRA A;  4OM5 A;  1CDR A;  3NH7 A;  1BTE A;  1NTN A;  1TGX A;  2ABX A;  2MHY A;  3BT1 U;  4IYE A;  2I9B E;  2PJY C;  2QJ9 C;  2HLR A;  2VLW A;  6EBX A;  1NXB A;  2MUO A;  1LXH A;  1LJZ A;  5IMT D;  1IKC A; 
#chains in the Genus database with same CATH topology
 1REW C;  2FD6 U;  1XT3 A;  1FSS B;  3PLC A;  2CTX A;  4KSN A;  5DU1 A;  1KBA A;  3KFD E;  1IJC A;  2JQP A;  1NOR A;  1CDT A;  1ERA A;  2J8B A;  1FFJ A;  2L5S A;  1F94 A;  1W6B A;  1G6M A;  4QTI U;  3LAQ U;  1TFS A;  1CVO A;  1QM7 A;  1TXB A;  5DO6 A;  1YWH A;  1BXP A;  2NBT A;  1CDQ A;  2GOO B;  4ZQY A;  2N99 A;  2QJB C;  4LFT A;  5IMY C;  1NEA A;  2MUP A;  1CB9 A;  2H62 D;  2MJY A;  2CRT A;  1F8U B;  2QJA C;  1HC9 B;  1B41 B;  2H5F A;  1HOY A;  4FAO C;  1CXN A;  1V6P A;  1CRE A;  2CDX A;  2UX2 A;  4BIK B;  1KXI A;  2L03 A;  3NDS A;  2ERA A;  1CRF A;  2BHI A;  1DRS A;  1KU6 B;  1CTX A;  3U73 U;  1JBD A;  1M9Z A;  3BT2 U;  1ES7 B;  1COE A;  1LX5 B;  1JGK A;  1KBT A;  1HAA A;  2LA1 A;  2MJ4 A;  4EY8 B;  2H62 C;  2PJY B;  2JVE A;  1LSI A;  4FAO E;  1NYU A;  1MR6 A;  1KC4 A;  2UWR A;  1RGJ A;  2BTX A;  4UY2 C;  3EVS C;  1IQ9 A;  2MFA A;  1FAS A;  2OFS A;  1HAJ A;  5EBX A;  4BDT B;  1ONJ A;  4P7U A;  4AEA A;  4XJJ A;  1KTZ B;  1RL5 A;  3U74 U;  2H7Z B;  4HQP F;  1S4Y A;  2H8U A;  1I02 A;  1ZAD A;  2K3G A;  2LCR A;  1NTX A;  1CHV S;  4RUD A;  1HC9 A;  1JE9 A;  1KBS A;  2MJ0 A;  1KS6 A;  1IDG A;  2H64 C;  1QKD A;  3ERA A;  1CCQ A;  5DZ5 A;  2X8B B;  1MAH F;  2H7Z A;  2GOO C;  1KFH A;  3VTS A;  1KL8 A;  2QC1 A;  3QB4 B;  4OM4 A;  1UG4 A;  2CCX A;  3NEQ A;  1L4W A;  1PLO A;  1TXA A;  3EBX A;  3FEV A;  1FF4 A;  1NYS A;  1QKE A;  1LXG A;  2HLQ A;  2H64 B;  1CXO A;  2CRS A;  3KFD I;  1COD A;  1IDL A;  1IDH A;  4DO8 A;  1VB0 A;  1FSC A;  1IK8 A;  1ERG A;  1IDI A;  3HH7 A;  1H0J A;  1CDS A;  1ABT A;  1FRA A;  4OM5 A;  1CDR A;  3NH7 A;  1BTE A;  1NTN A;  1TGX A;  2ABX A;  2MHY A;  3BT1 U;  4IYE A;  2I9B E;  2PJY C;  2QJ9 C;  2HLR A;  2VLW A;  6EBX A;  1NXB A;  2MUO A;  1LXH A;  1LJZ A;  5IMT D;  1IKC A; 
#chains in the Genus database with same CATH homology
 1REW C;  2FD6 U;  1XT3 A;  1FSS B;  3PLC A;  2CTX A;  4KSN A;  5DU1 A;  1KBA A;  3KFD E;  1IJC A;  2JQP A;  1NOR A;  1CDT A;  1ERA A;  2J8B A;  1FFJ A;  2L5S A;  1F94 A;  1W6B A;  1G6M A;  4QTI U;  3LAQ U;  1TFS A;  1CVO A;  1QM7 A;  1TXB A;  5DO6 A;  1YWH A;  1BXP A;  2NBT A;  1CDQ A;  2GOO B;  4ZQY A;  2N99 A;  2QJB C;  4LFT A;  5IMY C;  1NEA A;  2MUP A;  1CB9 A;  2H62 D;  2MJY A;  2CRT A;  1F8U B;  2QJA C;  1HC9 B;  1B41 B;  2H5F A;  1HOY A;  4FAO C;  1CXN A;  1V6P A;  1CRE A;  2CDX A;  2UX2 A;  4BIK B;  1KXI A;  2L03 A;  3NDS A;  2ERA A;  1CRF A;  2BHI A;  1DRS A;  1KU6 B;  1CTX A;  3U73 U;  1JBD A;  1M9Z A;  3BT2 U;  1ES7 B;  1COE A;  1LX5 B;  1JGK A;  1KBT A;  1HAA A;  2LA1 A;  2MJ4 A;  4EY8 B;  2H62 C;  2PJY B;  2JVE A;  1LSI A;  4FAO E;  1NYU A;  1MR6 A;  1KC4 A;  2UWR A;  1RGJ A;  2BTX A;  4UY2 C;  3EVS C;  1IQ9 A;  2MFA A;  1FAS A;  2OFS A;  1HAJ A;  5EBX A;  4BDT B;  1ONJ A;  4P7U A;  4AEA A;  4XJJ A;  1KTZ B;  1RL5 A;  3U74 U;  2H7Z B;  4HQP F;  1S4Y A;  2H8U A;  1I02 A;  1ZAD A;  2K3G A;  2LCR A;  1NTX A;  1CHV S;  4RUD A;  1HC9 A;  1JE9 A;  1KBS A;  2MJ0 A;  1KS6 A;  1IDG A;  2H64 C;  1QKD A;  3ERA A;  1CCQ A;  5DZ5 A;  2X8B B;  1MAH F;  2H7Z A;  2GOO C;  1KFH A;  3VTS A;  1KL8 A;  2QC1 A;  3QB4 B;  4OM4 A;  1UG4 A;  2CCX A;  3NEQ A;  1L4W A;  1PLO A;  1TXA A;  3EBX A;  3FEV A;  1FF4 A;  1NYS A;  1QKE A;  1LXG A;  2HLQ A;  2H64 B;  1CXO A;  2CRS A;  3KFD I;  1COD A;  1IDL A;  1IDH A;  4DO8 A;  1VB0 A;  1FSC A;  1IK8 A;  1ERG A;  1IDI A;  3HH7 A;  1H0J A;  1CDS A;  1ABT A;  1FRA A;  4OM5 A;  1CDR A;  3NH7 A;  1BTE A;  1NTN A;  1TGX A;  2ABX A;  2MHY A;  3BT1 U;  4IYE A;  2I9B E;  2PJY C;  2QJ9 C;  2HLR A;  2VLW A;  6EBX A;  1NXB A;  2MUO A;  1LXH A;  1LJZ A;  5IMT D;  1IKC A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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