2AIKX

Formylglycine generating enzyme c336s mutant covalently bound to substrate peptide lctpsra
Total Genus 78
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
78
sequence length
286
structure length
274
Chain Sequence
LAHSKMVPIPAGVFTMGTDDPQIKQDGEAPARRVTIDAFYMDAYEVSNTEFEKFVNSTGYLTEAEKFGDSFVFEGMLAAAPWWLPVKGANWRHPEGPDSTILHRPDHPVLHVSWNDAVAYCTWAGKRLPTEAEWEYSCRGGLHNRLFPWGNKLQPKGQHYANIWQGEFPVTNTGEDGFQGTAPVDAFPPNGYGLYNIVGNAWEWTSDWWTVHHSVEETLNPKGPPSGKDRVKKGGSYMSHRSYCYRYRCAARSQNTPDSSASNLGFRCAADRLP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Hydrolase activator,protein binding
molecule keywords Sulfatase modifying factor 1
publication title A general binding mechanism for all human sulfatases by the formylglycine-generating enzyme
pubmed doi rcsb
source organism Homo sapiens
total genus 78
structure length 274
sequence length 286
ec nomenclature ec 1.8.3.7: Formylglycine-generating enzyme.
pdb deposition date 2005-07-29

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
X PF03781 FGE-sulfatase Sulfatase-modifying factor enzyme 1
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.1580.10 Alpha Beta Alpha-Beta Complex paralog of FGE (formylglycine-generating enzyme) paralog of FGE (formylglycine-generating enzyme) 2aikX00
2HI8X 1YU4A 1Y1FX 1YU1A 1Y1HX 1YU3A 2HIBX 1Y1JX 1Z70X 2Q17A 2Y3CA 1YU2A 2IOUA 2AIKX 2AFYX 2AFTX 1Y1EX 1Y1IX 1Y4JA 2AIIX 1Y1GX 2AIJX 1YU0A
chains in the Genus database with same CATH superfamily
2HI8X 1YU4A 1Y1FX 1YU1A 1Y1HX 1YU3A 2HIBX 1Y1JX 1Z70X 2Q17A 2Y3CA 1YU2A 2IOUA 2AIKX 2AFYX 2AFTX 1Y1EX 1Y1IX 1Y4JA 2AIIX 1Y1GX 2AIJX 1YU0A
chains in the Genus database with same CATH topology
2HI8X 1YU4A 1Y1FX 1YU1A 1Y1HX 1YU3A 2HIBX 1Y1JX 1Z70X 2Q17A 2Y3CA 1YU2A 2IOUA 2AIKX 2AFYX 2AFTX 1Y1EX 1Y1IX 1Y4JA 2AIIX 1Y1GX 2AIJX 1YU0A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2HI8 X;  1YU4 A;  1Y1F X;  1YU1 A;  1Y1H X;  1YU3 A;  2HIB X;  1Y1J X;  1Z70 X;  2Q17 A;  2Y3C A;  1YU2 A;  2IOU A;  2AIK X;  2AFY X;  2AFT X;  1Y1E X;  1Y1I X;  1Y4J A;  2AII X;  1Y1G X;  2AIJ X;  1YU0 A; 
#chains in the Genus database with same CATH topology
 2HI8 X;  1YU4 A;  1Y1F X;  1YU1 A;  1Y1H X;  1YU3 A;  2HIB X;  1Y1J X;  1Z70 X;  2Q17 A;  2Y3C A;  1YU2 A;  2IOU A;  2AIK X;  2AFY X;  2AFT X;  1Y1E X;  1Y1I X;  1Y4J A;  2AII X;  1Y1G X;  2AIJ X;  1YU0 A; 
#chains in the Genus database with same CATH homology
 2HI8 X;  1YU4 A;  1Y1F X;  1YU1 A;  1Y1H X;  1YU3 A;  2HIB X;  1Y1J X;  1Z70 X;  2Q17 A;  2Y3C A;  1YU2 A;  2IOU A;  2AIK X;  2AFY X;  2AFT X;  1Y1E X;  1Y1I X;  1Y4J A;  2AII X;  1Y1G X;  2AIJ X;  1YU0 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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