2AUSA

Crystal structure of the archaeal box h/aca srnp nop10-cbf5 complex
Total Genus 85
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
85
sequence length
323
structure length
309
Chain Sequence
ADIKREVIVKDDKAETNPKWGFPPDKRPIELHIQYGVINLDKPPGPTSHEVVAWIKRILNLEKAGHGGTLDPKVSGVLPVALERATRVVQALLPAGKEYVALMHLHGDVPEDKIRAVMKEFEGEIIQRKVYYIEILEIDGRDVLFRVGVEAGTYIRSLIHHIGLALGVGAHMAELRRTRSGPFKEDETLVTLHDLVDYYHFWKEDGIEEYIRKAIQPMEKAVEHLPKIWIKDSAVAAVAHGANLTVPGIVKLNAGIKKGDLVAIMTLKDELVALGKAMMSTQEMIERSKGIAVDVEKVFMPRDWYPKLW
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords pseudouridine synthase
publication title Crystal structure determination and site-directed mutagenesis of the Pyrococcus abyssi aCBF5-aNOP10 complex reveal crucial roles of the C-terminal domains of both proteins in H/ACA sRNP activity
pubmed doi rcsb
source organism Pyrococcus abyssi
molecule tags Isomerase/structural protein
total genus 85
structure length 309
sequence length 323
chains with identical sequence C
ec nomenclature ec 5.4.99.25: tRNA pseudouridine(55) synthase.
pdb deposition date 2005-08-29

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01472 PUA PUA domain
A PF01509 TruB_N TruB family pseudouridylate synthase (N terminal domain)
A PF08068 DKCLD DKCLD (NUC011) domain
A PF16198 TruB_C_2 tRNA pseudouridylate synthase B C-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.30.130.70 Mainly Beta Roll Archaeosine Trna-guanine Transglycosylase; Chain: A, domain 4 Archaeosine Trna-guanine Transglycosylase; Chain: A, domain 4 2ausA01
3.30.2350.10 Alpha Beta 2-Layer Sandwich Pseudouridine synthase Pseudouridine synthase 2ausA02
1KSKA 3LWPA 3LWQA 1V9KA 1KSVA 3MQKA 1V9FA 2APOA 3LWOA 3ZV0C 1ZL3A 1XPIA 3DH3A 2HVYA 3U28A 1QYUA 2AB4A 2EY4A 3HAXA 1SGVA 1ZE2A 3HJYA 2RFKA 1KSLA 1ZE1A 2I82A 1R3FA 4LABA 2ISTA 1R3EA 3LWRA 4LGTA 1K8WA 3LWVA 3HJWA 3UAIA 1PRZA 2AUSA
chains in the Genus database with same CATH superfamily
2AS0A 1SZWA 3LWQA 2P38A 3ZV0C 3DH3A 3M6UA 1XNEA 1T5YA 1WXXA 4TZ4C 1QYUA 1Z2ZA 3HAXA 4Q1TA 1IQ8A 3M6WA 1Q7HA 2RFKA 1ZE1A 2I82A 4LABA 1R3EA 3LDFA 2CX0A 2J5VA 3M4XA 2Q07A 2APOA 2J5TA 1XPIA 3U28A 2CX1A 4CI1B 1WXWA 1SB7A 1SGVA 1ZE2A 3HJYA 4CI2B 4DMGA 2CWWA 3LWRA 3UAIA 1SI7A 3LJCA 1KSKA 1IT8A 3LWPA 1V9KA 3D79A 3MQKA 1KSVA 1ZL3A 1TE7A 1J2BA 2HVYA 2ANEA 1UOYA 3M6XA 1SQWA 1S04A 2EY4A 3C0KA 2KKUA 2DP9A 3M65A 1KSLA 1R3FA 2ISTA 3LWVA 1IT7A 2E5OA 1ZBOA 2Z0TA 3IUWA 1V9FA 3LWOA 1ZS7A 4CI3B 2FRXA 3M6VA 2AB4A 1WK2A 4LGTA 1K8WA 3HJWA 3VSEA 2B78A 1PRZA 2AUSA
chains in the Genus database with same CATH topology
1KSKA 1SZWA 3LWPA 3LWQA 1V9KA 3M4XA 3MQKA 1KSVA 1V9FA 2APOA 3LWOA 3ZV0C 1ZL3A 1XPIA 2FRXA 3DH3A 2HVYA 3M6XA 3M6VA 1UOYA 3M6UA 3U28A 1QYUA 2AB4A 2EY4A 1Z2ZA 3HAXA 1SB7A 1SGVA 1ZE2A 3M6WA 3HJYA 2RFKA 1KSLA 1ZE1A 2I82A 1R3FA 4LABA 2ISTA 1R3EA 3LWRA 4LGTA 1K8WA 3LWVA 3HJWA 3UAIA 1SI7A 1PRZA 2AUSA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1KSK A;  3LWP A;  3LWQ A;  1V9K A;  1KSV A;  3MQK A;  1V9F A;  2APO A;  3LWO A;  3ZV0 C;  1ZL3 A;  1XPI A;  3DH3 A;  2HVY A;  3U28 A;  1QYU A;  2AB4 A;  2EY4 A;  3HAX A;  1SGV A;  1ZE2 A;  3HJY A;  2RFK A;  1KSL A;  1ZE1 A;  2I82 A;  1R3F A;  4LAB A;  2IST A;  1R3E A;  3LWR A;  4LGT A;  1K8W A;  3LWV A;  3HJW A;  3UAI A;  1PRZ A;  2AUS A; 
#chains in the Genus database with same CATH topology
 2AS0 A;  1SZW A;  3LWQ A;  2P38 A;  3ZV0 C;  3DH3 A;  3M6U A;  1XNE A;  1T5Y A;  1WXX A;  4TZ4 C;  1QYU A;  1Z2Z A;  3HAX A;  4Q1T A;  1IQ8 A;  3M6W A;  1Q7H A;  2RFK A;  1ZE1 A;  2I82 A;  4LAB A;  1R3E A;  3LDF A;  2CX0 A;  2J5V A;  3M4X A;  2Q07 A;  2APO A;  2J5T A;  1XPI A;  3U28 A;  2CX1 A;  4CI1 B;  1WXW A;  1SB7 A;  1SGV A;  1ZE2 A;  3HJY A;  4CI2 B;  4DMG A;  2CWW A;  3LWR A;  3UAI A;  1SI7 A;  3LJC A;  1KSK A;  1IT8 A;  3LWP A;  1V9K A;  3D79 A;  3MQK A;  1KSV A;  1ZL3 A;  1TE7 A;  1J2B A;  2HVY A;  2ANE A;  1UOY A;  3M6X A;  1SQW A;  1S04 A;  2EY4 A;  3C0K A;  2KKU A;  2DP9 A;  3M65 A;  1KSL A;  1R3F A;  2IST A;  3LWV A;  1IT7 A;  2E5O A;  1ZBO A;  2Z0T A;  3IUW A;  1V9F A;  3LWO A;  1ZS7 A;  4CI3 B;  2FRX A;  3M6V A;  2AB4 A;  1WK2 A;  4LGT A;  1K8W A;  3HJW A;  3VSE A;  2B78 A;  1PRZ A;  2AUS A; 
#chains in the Genus database with same CATH homology
 1KSK A;  1SZW A;  3LWP A;  3LWQ A;  1V9K A;  3M4X A;  3MQK A;  1KSV A;  1V9F A;  2APO A;  3LWO A;  3ZV0 C;  1ZL3 A;  1XPI A;  2FRX A;  3DH3 A;  2HVY A;  3M6X A;  3M6V A;  1UOY A;  3M6U A;  3U28 A;  1QYU A;  2AB4 A;  2EY4 A;  1Z2Z A;  3HAX A;  1SB7 A;  1SGV A;  1ZE2 A;  3M6W A;  3HJY A;  2RFK A;  1KSL A;  1ZE1 A;  2I82 A;  1R3F A;  4LAB A;  2IST A;  1R3E A;  3LWR A;  4LGT A;  1K8W A;  3LWV A;  3HJW A;  3UAI A;  1SI7 A;  1PRZ A;  2AUS A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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#similar chains, but unknotted
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