2AUSA

Crystal structure of the archaeal box h/aca srnp nop10-cbf5 complex
Total Genus 85
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
85
sequence length
323
structure length
309
Chain Sequence
ADIKREVIVKDDKAETNPKWGFPPDKRPIELHIQYGVINLDKPPGPTSHEVVAWIKRILNLEKAGHGGTLDPKVSGVLPVALERATRVVQALLPAGKEYVALMHLHGDVPEDKIRAVMKEFEGEIIQRKVYYIEILEIDGRDVLFRVGVEAGTYIRSLIHHIGLALGVGAHMAELRRTRSGPFKEDETLVTLHDLVDYYHFWKEDGIEEYIRKAIQPMEKAVEHLPKIWIKDSAVAAVAHGANLTVPGIVKLNAGIKKGDLVAIMTLKDELVALGKAMMSTQEMIERSKGIAVDVEKVFMPRDWYPKLW
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure determination and site-directed mutagenesis of the Pyrococcus abyssi aCBF5-aNOP10 complex reveal crucial roles of the C-terminal domains of both proteins in H/ACA sRNP activity
pubmed doi rcsb
molecule keywords pseudouridine synthase
molecule tags Isomerase/structural protein
source organism Pyrococcus abyssi
total genus 85
structure length 309
sequence length 323
chains with identical sequence C
ec nomenclature ec 5.4.99.25: tRNA pseudouridine(55) synthase.
pdb deposition date 2005-08-29

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01472 PUA PUA domain
A PF01509 TruB_N TruB family pseudouridylate synthase (N terminal domain)
A PF08068 DKCLD DKCLD (NUC011) domain
A PF16198 TruB_C_2 tRNA pseudouridylate synthase B C-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.30.130.70 Mainly Beta Roll Archaeosine Trna-guanine Transglycosylase; Chain: A, domain 4 Archaeosine Trna-guanine Transglycosylase; Chain: A, domain 4 2ausA01
3.30.2350.10 Alpha Beta 2-Layer Sandwich Pseudouridine synthase Pseudouridine synthase 2ausA02
2APOA 2AUSA 3UAIA 1K8WA 3LWOA 4LABA 2HVYA 1ZE1A 1R3EA 3MQKA 3LWVA 1QYUA 3HJYA 1KSLA 1SGVA 3LWQA 1KSKA 3HJWA 1V9KA 2ISTA 1R3FA 1V9FA 3HAXA 1KSVA 2I82A 1XPIA 3DH3A 3LWPA 1PRZA 4LGTA 1ZL3A 3U28A 2AB4A 1ZE2A 3ZV0C 3LWRA 2EY4A 2RFKA
chains in the Genus database with same CATH superfamily
3UAIA 1IT8A 3MQKA 3LWVA 1KSLA 3LWQA 2AS0A 1T5YA 2DP9A 1SB7A 1SZWA 4CI1B 2J5VA 1R3FA 1V9FA 2I82A 1S04A 1WK2A 3LWPA 2AB4A 2E5OA 3LWRA 2RFKA 1K8WA 2FRXA 1WXXA 1SI7A 1WXWA 2J5TA 1QYUA 3HJYA 4DMGA 3M65A 2P38A 1XNEA 1V9KA 2ISTA 1Q7HA 4TZ4C 3M6XA 1Z2ZA 1IQ8A 3LDFA 1IT7A 2KKUA 3ZV0C 1ZE2A 2Z0TA 2APOA 3LWOA 3M6WA 2B78A 1R3EA 2ANEA 2Q07A 3M6UA 1TE7A 3HJWA 3M4XA 1UOYA 4CI3B 3M6VA 4LGTA 1SQWA 3IUWA 3C0KA 1J2BA 1ZS7A 2CX1A 2AUSA 4LABA 2HVYA 1ZE1A 1SGVA 2CWWA 1KSKA 4CI2B 3HAXA 1KSVA 2CX0A 3D79A 1XPIA 3DH3A 4Q1TA 3VSEA 1PRZA 1ZL3A 3U28A 1ZBOA 3LJCA 2EY4A
chains in the Genus database with same CATH topology
2APOA 2AUSA 3UAIA 1K8WA 3LWOA 2FRXA 4LABA 2HVYA 3M6WA 1ZE1A 1SI7A 1R3EA 3MQKA 3LWVA 1QYUA 3HJYA 1KSLA 1SGVA 3M6UA 3LWQA 1SB7A 1SZWA 1KSKA 3HJWA 1V9KA 2ISTA 3M4XA 1UOYA 3M6XA 1R3FA 1V9FA 3HAXA 1KSVA 2I82A 1XPIA 3DH3A 1Z2ZA 3LWPA 1PRZA 3M6VA 4LGTA 3U28A 1ZL3A 2AB4A 1ZE2A 3ZV0C 3LWRA 2EY4A 2RFKA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2APO A;  2AUS A;  3UAI A;  1K8W A;  3LWO A;  4LAB A;  2HVY A;  1ZE1 A;  1R3E A;  3MQK A;  3LWV A;  1QYU A;  3HJY A;  1KSL A;  1SGV A;  3LWQ A;  1KSK A;  3HJW A;  1V9K A;  2IST A;  1R3F A;  1V9F A;  3HAX A;  1KSV A;  2I82 A;  1XPI A;  3DH3 A;  3LWP A;  1PRZ A;  4LGT A;  1ZL3 A;  3U28 A;  2AB4 A;  1ZE2 A;  3ZV0 C;  3LWR A;  2EY4 A;  2RFK A; 
#chains in the Genus database with same CATH topology
 3UAI A;  1IT8 A;  3MQK A;  3LWV A;  1KSL A;  3LWQ A;  2AS0 A;  1T5Y A;  2DP9 A;  1SB7 A;  1SZW A;  4CI1 B;  2J5V A;  1R3F A;  1V9F A;  2I82 A;  1S04 A;  1WK2 A;  3LWP A;  2AB4 A;  2E5O A;  3LWR A;  2RFK A;  1K8W A;  2FRX A;  1WXX A;  1SI7 A;  1WXW A;  2J5T A;  1QYU A;  3HJY A;  4DMG A;  3M65 A;  2P38 A;  1XNE A;  1V9K A;  2IST A;  1Q7H A;  4TZ4 C;  3M6X A;  1Z2Z A;  1IQ8 A;  3LDF A;  1IT7 A;  2KKU A;  3ZV0 C;  1ZE2 A;  2Z0T A;  2APO A;  3LWO A;  3M6W A;  2B78 A;  1R3E A;  2ANE A;  2Q07 A;  3M6U A;  1TE7 A;  3HJW A;  3M4X A;  1UOY A;  4CI3 B;  3M6V A;  4LGT A;  1SQW A;  3IUW A;  3C0K A;  1J2B A;  1ZS7 A;  2CX1 A;  2AUS A;  4LAB A;  2HVY A;  1ZE1 A;  1SGV A;  2CWW A;  1KSK A;  4CI2 B;  3HAX A;  1KSV A;  2CX0 A;  3D79 A;  1XPI A;  3DH3 A;  4Q1T A;  3VSE A;  1PRZ A;  1ZL3 A;  3U28 A;  1ZBO A;  3LJC A;  2EY4 A; 
#chains in the Genus database with same CATH homology
 2APO A;  2AUS A;  3UAI A;  1K8W A;  3LWO A;  2FRX A;  4LAB A;  2HVY A;  3M6W A;  1ZE1 A;  1SI7 A;  1R3E A;  3MQK A;  3LWV A;  1QYU A;  3HJY A;  1KSL A;  1SGV A;  3M6U A;  3LWQ A;  1SB7 A;  1SZW A;  1KSK A;  3HJW A;  1V9K A;  2IST A;  3M4X A;  1UOY A;  3M6X A;  1R3F A;  1V9F A;  3HAX A;  1KSV A;  2I82 A;  1XPI A;  3DH3 A;  1Z2Z A;  3LWP A;  1PRZ A;  3M6V A;  4LGT A;  3U28 A;  1ZL3 A;  2AB4 A;  1ZE2 A;  3ZV0 C;  3LWR A;  2EY4 A;  2RFK A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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#similar chains, but unknotted
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