2AVTA

Crystal structure of the beta subunit from dna polymerase of streptococcus pyogenes
Total Genus 92
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
92
sequence length
377
structure length
372
Chain Sequence
MIQFSINRTLFIHALNTTKRAISTKNAIPILSSIKIEVTSTGVTLTGSNGQISIENTIPVGLLITSPGAILLEASFFINIISSLPDISINVKEIEQHQVVLTSGKSEITLKGKDVDQYPRLQEVSTENPLILKTKLLKSIIAETAFAASLQESRPILTGVHIVLSNHKDFKAVATDSHRMSQRLITLDNTSADFMVVLPSKSLREFSAVFTDDIETVEVFFSPSQILFRSEHISFYTRLLEGNYPDTDRLLMTEFETEVVFNTQSLRHAMERAFLISNATQNGTVKLEITQNHISAHVNSPEVGKVNEDLDIVSQSGSDLTISFNPTYLIESLKAIKSETVKIHFLSPVRPFTLTPGDEEESFIQLITPVRT
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of a DNA polymerase sliding clamp from a Gram-positive bacterium.
pubmed doi rcsb
molecule keywords DNA polymerase III beta subunit
molecule tags Transferase
source organism Streptococcus pyogenes
total genus 92
structure length 372
sequence length 377
chains with identical sequence B
ec nomenclature ec 2.7.7.-:
pdb deposition date 2005-08-30

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00712 DNA_pol3_beta DNA polymerase III beta subunit, N-terminal domain
A PF02767 DNA_pol3_beta_2 DNA polymerase III beta subunit, central domain
A PF02768 DNA_pol3_beta_3 DNA polymerase III beta subunit, C-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.10.150.10 Alpha Beta Roll DNA Polymerase III; Chain A, domain 2 DNA Polymerase III, subunit A, domain 2 2avtA01
3.70.10.10 Alpha Beta Box Proliferating Cell Nuclear Antigen Proliferating Cell Nuclear Antigen 2avtA02
2HIIB 1MMIA 1B77A 3WGWA 4N97A 3GPNA 2NTIA 1UD9A 1CZDA 2ZVVA 3G65B 4TR7A 3FDSD 3GGRB 2IZOB 4TSZA 3AIZC 2IZOC 1AXCA 5E0UA 4TR8A 3D1GA 2AVTA 1PLRA 4K3PA 4N95A 5CFKA 4N9AA 5AH4A 1OK7A 1VYMA 3V60B 5B7OA 3AIXA 1RXMA 5A6DA 3A1JA 3F1VA 3L0XA 2POLA 1GE8A 2OD8A 4HK1A 4MJPA 3GPMA 4CS5A 2NTIC 1UNNA 3U5ZF 2ZVKA 4K3SA 4PNWA 4S3IA 1JQLA 3QSBB 1VPKA 2ZVMA 2IX2A 3T0PA 4D2GA 1ISQA 1RXZA 1IZ4A 5FVEA 3A2FB 5FRQA 5E0VA 1YYPA 4K3OA 3VKXA 3FDSC 3P87A 2HIKA 2HIIA 4K3LA 4YHRA 5IY4A 2Z0LA 4RJFA 1IZ5A 1JQJA 1W60A 4TR6A 3RB9A 2IO4B 3G65A 3P91A 4K3QA 3GGRA 5AGUA 3A1JC 3I2MX 4N96A 2NTIB 3L10A 4OVHA 2IJXA 2ZVWA 3LX1A 5DAIA 2AWAA 3D1FA 5IWDA 1RWZA 1DMLA 4TRTA 3V62B 3U60F 4MJRA 1UL1A 4PNUA 3P83A 4L6PA 5DA7A 3PGEB 1PLQA 5AH2A 3P16A 4ZTDA 1U7BA 3L0WA 3PWEA 4MJQA 3LX2A 3TBLA 2HIKC 2ZVLA 2HIIC 3Q4KA 4N98A 5H0TA 5AGVA 4OVFA 3F1WA 3HSLX 3K4XA 3AIXB 3G65C 3D1EA 3A1JB 5IXAA 3AIZA 3QSBA 5HACA 4K3RA 1VYJA 3GGRC 5E0TA 3IFVA 5JNED 4K3MA 3U61F 3BEPA 4N99A 3HI8A 4L60A 3Q4LA 2XURA 2IX2B 4PNVA 2IX2C 4N94A 4OVGA 4RKIA 1U76A 3V61B 1T6LA 5AUJA 3Q4JA 4K3KA 4K74A 1B8HA 2IO4A 1SXJF 2HIKB
chains in the Genus database with same CATH superfamily
2HIIB 1MMIA 1B77A 3WGWA 4N97A 3GPNA 2NTIA 1UD9A 1CZDA 2ZVVA 3G65B 4TR7A 3FDSD 3GGRB 2IZOB 4TSZA 3AIZC 2IZOC 3PGEA 1AXCA 5E0UA 4TR8A 3D1GA 2AVTA 4K3PA 1PLRA 4N95A 5CFKA 4N9AA 5AH4A 1OK7A 1VYMA 3V60B 3L0WB 5B7OA 3AIXA 1RXMA 5A6DA 3A1JA 3F1VA 3L0XA 2POLA 1GE8A 2OD8A 4HK1A 4MJPA 3GPMA 4CS5A 2NTIC 1UNNA 3U5ZF 2ZVKA 4K3SA 4PNWA 4S3IA 1JQLA 3QSBB 1VPKA 2ZVMA 2IX2A 3T0PA 4D2GA 1ISQA 1RXZA 1IZ4A 5FVEA 3A2FB 5FRQA 5E0VA 1YYPA 4K3OA 3VKXA 3FDSC 3P87A 2HIKA 2HIIA 4K3LA 4YHRA 5IY4A 2Z0LA 4RJFA 1IZ5A 1JQJA 1W60A 4TR6A 3RB9A 2IO4B 3G65A 3P91A 4K3QA 3GGRA 5AGUA 3A1JC 3I2MX 4N96A 2NTIB 3L10A 4OVHA 2IJXA 2ZVWA 3LX1A 5DAIA 2AWAA 3D1FA 5IWDA 1RWZA 1DMLA 4TRTA 3V62B 3U60F 4MJRA 1UL1A 4PNUA 3P83A 4L6PA 5DA7A 3PGEB 1PLQA 5AH2A 3P16A 4ZTDA 1U7BA 3L0WA 3PWEA 4MJQA 3LX2A 3TBLA 2HIKC 2ZVLA 2HIIC 3Q4KA 4N98A 5H0TA 5AGVA 4OVFA 3F1WA 3HSLX 3K4XA 3AIXB 3G65C 3D1EA 3A1JB 3L0XB 5IXAA 3AIZA 3QSBA 5HACA 4K3RA 1VYJA 3GGRC 5E0TA 3IFVA 5JNED 3L10B 4K3MA 3U61F 3BEPA 4N99A 3HI8A 4L60A 3Q4LA 2XURA 2IX2B 4PNVA 2IX2C 4N94A 4OVGA 4RKIA 1U76A 3V61B 1T6LA 5AUJA 3Q4JA 4K3KA 4K74A 1B8HA 2IO4A 1SXJF 2HIKB
chains in the Genus database with same CATH topology
2HIIB 1MMIA 1B77A 3WGWA 4N97A 3GPNA 2NTIA 1UD9A 1CZDA 2ZVVA 3G65B 4TR7A 3FDSD 3GGRB 2IZOB 4TSZA 3AIZC 2IZOC 1AXCA 5E0UA 4TR8A 3D1GA 2AVTA 1PLRA 4K3PA 4N95A 5CFKA 4N9AA 5AH4A 1OK7A 1VYMA 3V60B 5B7OA 3AIXA 1RXMA 5A6DA 3A1JA 3F1VA 3L0XA 2POLA 1GE8A 2OD8A 4HK1A 4MJPA 3GPMA 4CS5A 2NTIC 1UNNA 3U5ZF 2ZVKA 4K3SA 4PNWA 4S3IA 1JQLA 3QSBB 1VPKA 2ZVMA 2IX2A 3T0PA 4D2GA 1ISQA 1RXZA 1IZ4A 5FVEA 3A2FB 5FRQA 5E0VA 1YYPA 4K3OA 3VKXA 3FDSC 3P87A 2HIKA 2HIIA 4K3LA 4YHRA 5IY4A 2Z0LA 4RJFA 1IZ5A 1JQJA 1W60A 4TR6A 3RB9A 2IO4B 3G65A 3P91A 4K3QA 3GGRA 5AGUA 3A1JC 3I2MX 4N96A 2NTIB 3L10A 4OVHA 2IJXA 2ZVWA 3LX1A 5DAIA 2AWAA 3D1FA 5IWDA 1RWZA 1DMLA 4TRTA 3V62B 3U60F 4MJRA 1UL1A 4PNUA 3P83A 4L6PA 5DA7A 3PGEB 1PLQA 5AH2A 3P16A 4ZTDA 1U7BA 3L0WA 3PWEA 4MJQA 3LX2A 3TBLA 2HIKC 2ZVLA 2HIIC 3Q4KA 4N98A 5H0TA 5AGVA 4OVFA 3F1WA 3HSLX 3K4XA 3AIXB 3G65C 3D1EA 3A1JB 5IXAA 3AIZA 3QSBA 5HACA 4K3RA 1VYJA 3GGRC 5E0TA 3IFVA 5JNED 4K3MA 3U61F 3BEPA 4N99A 3HI8A 4L60A 3Q4LA 2XURA 2IX2B 4PNVA 2IX2C 4N94A 4OVGA 4RKIA 1U76A 3V61B 1T6LA 5AUJA 3Q4JA 4K3KA 4K74A 1B8HA 2IO4A 1SXJF 2HIKB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2HII B;  1MMI A;  1B77 A;  3WGW A;  4N97 A;  3GPN A;  2NTI A;  1UD9 A;  1CZD A;  2ZVV A;  3G65 B;  4TR7 A;  3FDS D;  3GGR B;  2IZO B;  4TSZ A;  3AIZ C;  2IZO C;  1AXC A;  5E0U A;  4TR8 A;  3D1G A;  2AVT A;  1PLR A;  4K3P A;  4N95 A;  5CFK A;  4N9A A;  5AH4 A;  1OK7 A;  1VYM A;  3V60 B;  5B7O A;  3AIX A;  1RXM A;  5A6D A;  3A1J A;  3F1V A;  3L0X A;  2POL A;  1GE8 A;  2OD8 A;  4HK1 A;  4MJP A;  3GPM A;  4CS5 A;  2NTI C;  1UNN A;  3U5Z F;  2ZVK A;  4K3S A;  4PNW A;  4S3I A;  1JQL A;  3QSB B;  1VPK A;  2ZVM A;  2IX2 A;  3T0P A;  4D2G A;  1ISQ A;  1RXZ A;  1IZ4 A;  5FVE A;  3A2F B;  5FRQ A;  5E0V A;  1YYP A;  4K3O A;  3VKX A;  3FDS C;  3P87 A;  2HIK A;  2HII A;  4K3L A;  4YHR A;  5IY4 A;  2Z0L A;  4RJF A;  1IZ5 A;  1JQJ A;  1W60 A;  4TR6 A;  3RB9 A;  2IO4 B;  3G65 A;  3P91 A;  4K3Q A;  3GGR A;  5AGU A;  3A1J C;  3I2M X;  4N96 A;  2NTI B;  3L10 A;  4OVH A;  2IJX A;  2ZVW A;  3LX1 A;  5DAI A;  2AWA A;  3D1F A;  5IWD A;  1RWZ A;  1DML A;  4TRT A;  3V62 B;  3U60 F;  4MJR A;  1UL1 A;  4PNU A;  3P83 A;  4L6P A;  5DA7 A;  3PGE B;  1PLQ A;  5AH2 A;  3P16 A;  4ZTD A;  1U7B A;  3L0W A;  3PWE A;  4MJQ A;  3LX2 A;  3TBL A;  2HIK C;  2ZVL A;  2HII C;  3Q4K A;  4N98 A;  5H0T A;  5AGV A;  4OVF A;  3F1W A;  3HSL X;  3K4X A;  3AIX B;  3G65 C;  3D1E A;  3A1J B;  5IXA A;  3AIZ A;  3QSB A;  5HAC A;  4K3R A;  1VYJ A;  3GGR C;  5E0T A;  3IFV A;  5JNE D;  4K3M A;  3U61 F;  3BEP A;  4N99 A;  3HI8 A;  4L60 A;  3Q4L A;  2XUR A;  2IX2 B;  4PNV A;  2IX2 C;  4N94 A;  4OVG A;  4RKI A;  1U76 A;  3V61 B;  1T6L A;  5AUJ A;  3Q4J A;  4K3K A;  4K74 A;  1B8H A;  2IO4 A;  1SXJ F;  2HIK B; 
#chains in the Genus database with same CATH topology
 2HII B;  1MMI A;  1B77 A;  3WGW A;  4N97 A;  3GPN A;  2NTI A;  1UD9 A;  1CZD A;  2ZVV A;  3G65 B;  4TR7 A;  3FDS D;  3GGR B;  2IZO B;  4TSZ A;  3AIZ C;  2IZO C;  3PGE A;  1AXC A;  5E0U A;  4TR8 A;  3D1G A;  2AVT A;  4K3P A;  1PLR A;  4N95 A;  5CFK A;  4N9A A;  5AH4 A;  1OK7 A;  1VYM A;  3V60 B;  3L0W B;  5B7O A;  3AIX A;  1RXM A;  5A6D A;  3A1J A;  3F1V A;  3L0X A;  2POL A;  1GE8 A;  2OD8 A;  4HK1 A;  4MJP A;  3GPM A;  4CS5 A;  2NTI C;  1UNN A;  3U5Z F;  2ZVK A;  4K3S A;  4PNW A;  4S3I A;  1JQL A;  3QSB B;  1VPK A;  2ZVM A;  2IX2 A;  3T0P A;  4D2G A;  1ISQ A;  1RXZ A;  1IZ4 A;  5FVE A;  3A2F B;  5FRQ A;  5E0V A;  1YYP A;  4K3O A;  3VKX A;  3FDS C;  3P87 A;  2HIK A;  2HII A;  4K3L A;  4YHR A;  5IY4 A;  2Z0L A;  4RJF A;  1IZ5 A;  1JQJ A;  1W60 A;  4TR6 A;  3RB9 A;  2IO4 B;  3G65 A;  3P91 A;  4K3Q A;  3GGR A;  5AGU A;  3A1J C;  3I2M X;  4N96 A;  2NTI B;  3L10 A;  4OVH A;  2IJX A;  2ZVW A;  3LX1 A;  5DAI A;  2AWA A;  3D1F A;  5IWD A;  1RWZ A;  1DML A;  4TRT A;  3V62 B;  3U60 F;  4MJR A;  1UL1 A;  4PNU A;  3P83 A;  4L6P A;  5DA7 A;  3PGE B;  1PLQ A;  5AH2 A;  3P16 A;  4ZTD A;  1U7B A;  3L0W A;  3PWE A;  4MJQ A;  3LX2 A;  3TBL A;  2HIK C;  2ZVL A;  2HII C;  3Q4K A;  4N98 A;  5H0T A;  5AGV A;  4OVF A;  3F1W A;  3HSL X;  3K4X A;  3AIX B;  3G65 C;  3D1E A;  3A1J B;  3L0X B;  5IXA A;  3AIZ A;  3QSB A;  5HAC A;  4K3R A;  1VYJ A;  3GGR C;  5E0T A;  3IFV A;  5JNE D;  3L10 B;  4K3M A;  3U61 F;  3BEP A;  4N99 A;  3HI8 A;  4L60 A;  3Q4L A;  2XUR A;  2IX2 B;  4PNV A;  2IX2 C;  4N94 A;  4OVG A;  4RKI A;  1U76 A;  3V61 B;  1T6L A;  5AUJ A;  3Q4J A;  4K3K A;  4K74 A;  1B8H A;  2IO4 A;  1SXJ F;  2HIK B; 
#chains in the Genus database with same CATH homology
 2HII B;  1MMI A;  1B77 A;  3WGW A;  4N97 A;  3GPN A;  2NTI A;  1UD9 A;  1CZD A;  2ZVV A;  3G65 B;  4TR7 A;  3FDS D;  3GGR B;  2IZO B;  4TSZ A;  3AIZ C;  2IZO C;  1AXC A;  5E0U A;  4TR8 A;  3D1G A;  2AVT A;  1PLR A;  4K3P A;  4N95 A;  5CFK A;  4N9A A;  5AH4 A;  1OK7 A;  1VYM A;  3V60 B;  5B7O A;  3AIX A;  1RXM A;  5A6D A;  3A1J A;  3F1V A;  3L0X A;  2POL A;  1GE8 A;  2OD8 A;  4HK1 A;  4MJP A;  3GPM A;  4CS5 A;  2NTI C;  1UNN A;  3U5Z F;  2ZVK A;  4K3S A;  4PNW A;  4S3I A;  1JQL A;  3QSB B;  1VPK A;  2ZVM A;  2IX2 A;  3T0P A;  4D2G A;  1ISQ A;  1RXZ A;  1IZ4 A;  5FVE A;  3A2F B;  5FRQ A;  5E0V A;  1YYP A;  4K3O A;  3VKX A;  3FDS C;  3P87 A;  2HIK A;  2HII A;  4K3L A;  4YHR A;  5IY4 A;  2Z0L A;  4RJF A;  1IZ5 A;  1JQJ A;  1W60 A;  4TR6 A;  3RB9 A;  2IO4 B;  3G65 A;  3P91 A;  4K3Q A;  3GGR A;  5AGU A;  3A1J C;  3I2M X;  4N96 A;  2NTI B;  3L10 A;  4OVH A;  2IJX A;  2ZVW A;  3LX1 A;  5DAI A;  2AWA A;  3D1F A;  5IWD A;  1RWZ A;  1DML A;  4TRT A;  3V62 B;  3U60 F;  4MJR A;  1UL1 A;  4PNU A;  3P83 A;  4L6P A;  5DA7 A;  3PGE B;  1PLQ A;  5AH2 A;  3P16 A;  4ZTD A;  1U7B A;  3L0W A;  3PWE A;  4MJQ A;  3LX2 A;  3TBL A;  2HIK C;  2ZVL A;  2HII C;  3Q4K A;  4N98 A;  5H0T A;  5AGV A;  4OVF A;  3F1W A;  3HSL X;  3K4X A;  3AIX B;  3G65 C;  3D1E A;  3A1J B;  5IXA A;  3AIZ A;  3QSB A;  5HAC A;  4K3R A;  1VYJ A;  3GGR C;  5E0T A;  3IFV A;  5JNE D;  4K3M A;  3U61 F;  3BEP A;  4N99 A;  3HI8 A;  4L60 A;  3Q4L A;  2XUR A;  2IX2 B;  4PNV A;  2IX2 C;  4N94 A;  4OVG A;  4RKI A;  1U76 A;  3V61 B;  1T6L A;  5AUJ A;  3Q4J A;  4K3K A;  4K74 A;  1B8H A;  2IO4 A;  1SXJ F;  2HIK B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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