2BQ0A

14-3-3 protein beta (human)
Total Genus 102
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
102
sequence length
230
structure length
230
Chain Sequence
MDKSELVQKAKLAEQAERYDDMAAAMKAVTEQGHELSNEERNLLSVAYKNVVGARRSSWRVISSIEQKTERNEKKQQMGKEYREKIEAELQDICNDVLELLDKYLIPNATQPESKVFYLKMKGDYFRYLSEVASGDNKQTTVSNSQQAYQEAFEISKKEMQPTHPIRLGLALNFSVFYYEILNSPEKACSLAKTAFDEAIAELDTLNEESYKDSTLIMQLLRDNLTLWTS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural Basis for Protein-Protein Interactions in the 14-3-3 Protein Family.
pubmed doi rcsb
molecule tags Cell regulator protein
source organism Homo sapiens
molecule keywords 14-3-3 BETA/ALPHA
total genus 102
structure length 230
sequence length 230
chains with identical sequence B
ec nomenclature
pdb deposition date 2005-04-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00244 14-3-3 14-3-3 protein
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.190.20 Mainly Alpha Up-down Bundle Delta-Endotoxin; domain 1 14-3-3 domain 2bq0A00
4DAUA 2C63A 4DHOA 2WH0A 3UZDA 4DHUA 5LU2A 5D3EA 3M51A 4JC3A 4JDDA 3U9XA 5BY9A 3AXYC 3P1OA 1YWTA 2O98A 3SMOA 1O9CA 4DHMA 5BTVA 3M50A 1QJBA 4DNKA 2O8PA 2BQ0A 4BG6A 2NPMA 4HKCA 5F74A 4DHTA 4FR3A 1A4OA 3P1SA 1QJAA 1A37A 2C1NA 1IB1A 3SMLA 2BR9A 3SPRA 4DHSA 4Y3BA 5J31A 2B05A 3IQUA 5LHOA 1A38A 3SMMA 4O46A 5EWZA 4DHNA 3MHRA 5HF3A 2V7DA 3SMKA 3UX0A 4IHLA 5LVZA 3P1NA 3LW1A 4GNTA 4ZQ0A 4F7RA 2O02A 3E6YA 4N7YA 2C74A 4DHQA 5D2DA 3P1RA 4Y32A 4WRQA 4Y5IA 4IEAA 1O9EA 5EXAA 1YZ5A 4DHPA 3T0LA 3UALA 3T0MA 3IQVA 3SMNA 5D3FA 1O9DA 2BTPA 2C23A 1O9FA 3EFZA 3P1QA 3SP5A 4E2EA 5LU1A 3UBWA 4N7GA 4ZDRA 4DHRA 4DX0A 5IQPA 3O8IA 4QLIA 4DATA 3NKXA 3CU8A 3IQJA 4FJ3A 4FL5A 2C1JA 4N84A 5LX2A 3P1PA 4J6SA 3RDHA
chains in the Genus database with same CATH superfamily
4DAUA 2C63A 4DHOA 2WH0A 3UZDA 4DHUA 5LU2A 5D3EA 3M51A 4JC3A 4JDDA 3U9XA 5BY9A 3AXYC 1I5PA 3P1OA 3CQCA 1YWTA 2O98A 1O9CA 3SMOA 1URJA 4DHMA 5BTVA 3M50A 1QJBA 4DNKA 2O8PA 2BQ0A 4ARYA 4BG6A 2NPMA 4HKCA 5F74A 2C9KA 4DHTA 4FR3A 1A4OA 3P1SA 1QJAA 1A37A 3X0UA 2C1NA 4QX2A 1IB1A 3SMLA 2BR9A 3SPRA 4DHSA 4Y3BA 1S2XA 5J31A 4QX3A 2B05A 4QX1A 3IQUA 5LHOA 1A38A 3SMMA 4O46A 5EWZA 4DHNA 3I4RA 3MHRA 5HF3A 2V7DA 3SMKA 3UX0A 4IHLA 1W99A 5LVZA 3P1NA 3LW1A 4GNTA 4ZQ0A 4F7RA 2O02A 1JI6A 4MOAA 4QX0A 3E6YA 4N7YA 2C74A 4DHQA 5D2DA 3P1RA 4Y32A 4WRQA 4Y5IA 4IEAA 1O9EA 5EXAA 1YZ5A 4DHPA 3T0LA 3UALA 3T0MA 3IQVA 3SMNA 5D3FA 1O9DA 2BTPA 2C23A 4ARXA 1O9FA 3EFZA 3P1QA 3SP5A 4E2EA 5LU1A 3CQGA 4W8JA 3UBWA 4N7GA 1CIYA 4ZDRA 4DHRA 4DX0A 4D8MA 5IQPA 3O8IA 4QLIA 4DATA 3NKXA 3CU8A 3IQJA 4FJ3A 4FL5A 2C1JA 4N84A 5LX2A 3P1PA 4J6SA 3RDHA 1DLCA 3EB7A 3ZHEB
chains in the Genus database with same CATH topology
4DAUA 2C63A 4DHOA 2WH0A 3UZDA 4DHUA 5LU2A 5D3EA 3M51A 4JC3A 4JDDA 3U9XA 5BY9A 3AXYC 3P1OA 1YWTA 2O98A 3SMOA 1O9CA 4DHMA 5BTVA 3M50A 1QJBA 4DNKA 2O8PA 2BQ0A 4BG6A 2NPMA 4HKCA 5F74A 4DHTA 4FR3A 1A4OA 3P1SA 1QJAA 1A37A 2C1NA 1IB1A 3SMLA 2BR9A 3SPRA 4DHSA 4Y3BA 5J31A 2B05A 3IQUA 5LHOA 1A38A 3SMMA 4O46A 5EWZA 4DHNA 3MHRA 5HF3A 2V7DA 3SMKA 3UX0A 4IHLA 5LVZA 3P1NA 3LW1A 4GNTA 4ZQ0A 4F7RA 2O02A 3E6YA 4N7YA 2C74A 4DHQA 5D2DA 3P1RA 4Y32A 4WRQA 4Y5IA 4IEAA 1O9EA 5EXAA 1YZ5A 4DHPA 3T0LA 3UALA 3T0MA 3IQVA 3SMNA 5D3FA 1O9DA 2BTPA 2C23A 1O9FA 3EFZA 3P1QA 3SP5A 4E2EA 5LU1A 3UBWA 4N7GA 4ZDRA 4DHRA 4DX0A 5IQPA 3O8IA 4QLIA 4DATA 3NKXA 3CU8A 3IQJA 4FJ3A 4FL5A 2C1JA 4N84A 5LX2A 3P1PA 4J6SA 3RDHA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4DAU A;  2C63 A;  4DHO A;  2WH0 A;  3UZD A;  4DHU A;  5LU2 A;  5D3E A;  3M51 A;  4JC3 A;  4JDD A;  3U9X A;  5BY9 A;  3AXY C;  3P1O A;  1YWT A;  2O98 A;  3SMO A;  1O9C A;  4DHM A;  5BTV A;  3M50 A;  1QJB A;  4DNK A;  2O8P A;  2BQ0 A;  4BG6 A;  2NPM A;  4HKC A;  5F74 A;  4DHT A;  4FR3 A;  1A4O A;  3P1S A;  1QJA A;  1A37 A;  2C1N A;  1IB1 A;  3SML A;  2BR9 A;  3SPR A;  4DHS A;  4Y3B A;  5J31 A;  2B05 A;  3IQU A;  5LHO A;  1A38 A;  3SMM A;  4O46 A;  5EWZ A;  4DHN A;  3MHR A;  5HF3 A;  2V7D A;  3SMK A;  3UX0 A;  4IHL A;  5LVZ A;  3P1N A;  3LW1 A;  4GNT A;  4ZQ0 A;  4F7R A;  2O02 A;  3E6Y A;  4N7Y A;  2C74 A;  4DHQ A;  5D2D A;  3P1R A;  4Y32 A;  4WRQ A;  4Y5I A;  4IEA A;  1O9E A;  5EXA A;  1YZ5 A;  4DHP A;  3T0L A;  3UAL A;  3T0M A;  3IQV A;  3SMN A;  5D3F A;  1O9D A;  2BTP A;  2C23 A;  1O9F A;  3EFZ A;  3P1Q A;  3SP5 A;  4E2E A;  5LU1 A;  3UBW A;  4N7G A;  4ZDR A;  4DHR A;  4DX0 A;  5IQP A;  3O8I A;  4QLI A;  4DAT A;  3NKX A;  3CU8 A;  3IQJ A;  4FJ3 A;  4FL5 A;  2C1J A;  4N84 A;  5LX2 A;  3P1P A;  4J6S A;  3RDH A; 
#chains in the Genus database with same CATH topology
 4DAU A;  2C63 A;  4DHO A;  2WH0 A;  3UZD A;  4DHU A;  5LU2 A;  5D3E A;  3M51 A;  4JC3 A;  4JDD A;  3U9X A;  5BY9 A;  3AXY C;  1I5P A;  3P1O A;  3CQC A;  1YWT A;  2O98 A;  1O9C A;  3SMO A;  1URJ A;  4DHM A;  5BTV A;  3M50 A;  1QJB A;  4DNK A;  2O8P A;  2BQ0 A;  4ARY A;  4BG6 A;  2NPM A;  4HKC A;  5F74 A;  2C9K A;  4DHT A;  4FR3 A;  1A4O A;  3P1S A;  1QJA A;  1A37 A;  3X0U A;  2C1N A;  4QX2 A;  1IB1 A;  3SML A;  2BR9 A;  3SPR A;  4DHS A;  4Y3B A;  1S2X A;  5J31 A;  4QX3 A;  2B05 A;  4QX1 A;  3IQU A;  5LHO A;  1A38 A;  3SMM A;  4O46 A;  5EWZ A;  4DHN A;  3I4R A;  3MHR A;  5HF3 A;  2V7D A;  3SMK A;  3UX0 A;  4IHL A;  1W99 A;  5LVZ A;  3P1N A;  3LW1 A;  4GNT A;  4ZQ0 A;  4F7R A;  2O02 A;  1JI6 A;  4MOA A;  4QX0 A;  3E6Y A;  4N7Y A;  2C74 A;  4DHQ A;  5D2D A;  3P1R A;  4Y32 A;  4WRQ A;  4Y5I A;  4IEA A;  1O9E A;  5EXA A;  1YZ5 A;  4DHP A;  3T0L A;  3UAL A;  3T0M A;  3IQV A;  3SMN A;  5D3F A;  1O9D A;  2BTP A;  2C23 A;  4ARX A;  1O9F A;  3EFZ A;  3P1Q A;  3SP5 A;  4E2E A;  5LU1 A;  3CQG A;  4W8J A;  3UBW A;  4N7G A;  1CIY A;  4ZDR A;  4DHR A;  4DX0 A;  4D8M A;  5IQP A;  3O8I A;  4QLI A;  4DAT A;  3NKX A;  3CU8 A;  3IQJ A;  4FJ3 A;  4FL5 A;  2C1J A;  4N84 A;  5LX2 A;  3P1P A;  4J6S A;  3RDH A;  1DLC A;  3EB7 A;  3ZHE B; 
#chains in the Genus database with same CATH homology
 4DAU A;  2C63 A;  4DHO A;  2WH0 A;  3UZD A;  4DHU A;  5LU2 A;  5D3E A;  3M51 A;  4JC3 A;  4JDD A;  3U9X A;  5BY9 A;  3AXY C;  3P1O A;  1YWT A;  2O98 A;  3SMO A;  1O9C A;  4DHM A;  5BTV A;  3M50 A;  1QJB A;  4DNK A;  2O8P A;  2BQ0 A;  4BG6 A;  2NPM A;  4HKC A;  5F74 A;  4DHT A;  4FR3 A;  1A4O A;  3P1S A;  1QJA A;  1A37 A;  2C1N A;  1IB1 A;  3SML A;  2BR9 A;  3SPR A;  4DHS A;  4Y3B A;  5J31 A;  2B05 A;  3IQU A;  5LHO A;  1A38 A;  3SMM A;  4O46 A;  5EWZ A;  4DHN A;  3MHR A;  5HF3 A;  2V7D A;  3SMK A;  3UX0 A;  4IHL A;  5LVZ A;  3P1N A;  3LW1 A;  4GNT A;  4ZQ0 A;  4F7R A;  2O02 A;  3E6Y A;  4N7Y A;  2C74 A;  4DHQ A;  5D2D A;  3P1R A;  4Y32 A;  4WRQ A;  4Y5I A;  4IEA A;  1O9E A;  5EXA A;  1YZ5 A;  4DHP A;  3T0L A;  3UAL A;  3T0M A;  3IQV A;  3SMN A;  5D3F A;  1O9D A;  2BTP A;  2C23 A;  1O9F A;  3EFZ A;  3P1Q A;  3SP5 A;  4E2E A;  5LU1 A;  3UBW A;  4N7G A;  4ZDR A;  4DHR A;  4DX0 A;  5IQP A;  3O8I A;  4QLI A;  4DAT A;  3NKX A;  3CU8 A;  3IQJ A;  4FJ3 A;  4FL5 A;  2C1J A;  4N84 A;  5LX2 A;  3P1P A;  4J6S A;  3RDH A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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