2BR7A

Crystal structure of acetylcholine-binding protein (achbp) from aplysia californica in complex with hepes
Total Genus 49
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
49
sequence length
205
structure length
205
Chain Sequence
QANLMRLKSDLFNRSPMYPGPTKDDPLTVTLGFTLQDIVKVDSSTNEVDLVYYEQQRWKLNSLMWDPNEYGNITDFRTSAADIWTPDITAYSSTRPVQVLSPQIAVVTHDGSVMFIPAQRLSFMCDPTGVDSEEGVTCAVKFGSWVYSGFEIDLKTDTDQVDLSSYYASSKYEILSATQTRQVQHYSCCPEPYIDVNLVVKFRER
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal Structure of Nicotinic Acetylcholine Receptor Homolog Achbp in Complex with an Alpha- Conotoxin Pnia Variant
pubmed doi rcsb
molecule keywords SOLUBLE ACETYLCHOLINE RECEPTOR
molecule tags Receptor protein
source organism Aplysia californica
total genus 49
structure length 205
sequence length 205
chains with identical sequence B, C, D, E
ec nomenclature
pdb deposition date 2005-05-03

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02931 Neur_chan_LBD Neurotransmitter-gated ion-channel ligand binding domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.70.170.10 Mainly Beta Distorted Sandwich Acetylcholine Binding Protein; Chain: A, Neurotransmitter-gated ion-channel ligand-binding domain 2br7A00
2QC1B 4BFQA 4AFHA 2ZJUA 4HFIA 4LMJA 3U8JA 3ZKRA 2Y7YA 3WTOA 4UM1A 4LMLA 2YMDA 3UU5A 4AFGA 3ZDGA 2XNTA 2W8GA 3U8LA 3RQUA 3U8MA 4COFA 1UW6A 2Y58A 4HFBA 1UV6A 3EI0A 4UXUA 3UU3A 3WTKA 4HFDA 3SH1A 2BG9E 4QACA 3WTLA 4XK9A 3RIFA 4ZR6A 4B5DA 2C9TA 2XYSA 2Y56A 3JADA 5KZUA 4IL9A 2XYTA 5J5GA 5AFHA 4UM3P 4ZJSA 5BP0A 4NPPA 2WNLA 5FJVA 2BYNA 4HFCA 5CO5A 3U8KA 3ZDHA 4ALXA 2BYPA 3RHWA 2XQAA 5IUXA 3WTMA 3WIPA 3SQ6A 2WZYA 4Z90A 5LXBA 2PGZA 2YMEA 5J0ZA 3RQWA 2XQ6A 4TWFA 4EZ1A 4IL4A 5AFJA 5AFMB 2YN6A 2XNUA 2BG9B 3P4WA 3RIAA 3RI5A 4NZBA 2XZ5A 2XQ4A 2BR7A 2XNVA 2BR8A 5HCMA 4UY2A 2X00A 4ZJTA 4BQTA 4XHEA 5HEUA 3GUAA 3IGQA 4UM3A 5LG3A 4QH1A 2BYSA 2XQ3A 3UU8A 5TVCA 3PEOA 4QH4A 5HEGA 4TNWA 5JMEA 3EAMA 3JAFA 4ZK1A 3P50A 5AFMA 4D01A 4ILBA 2Y57A 5SYOA 3UQ7A 2WNCA 3TLTA 2VL0A 2BJ0A 3WTIA 4ZK4A 4UM3S 5L4EA 4WV9A 3JAEA 3SIOA 2XZ6A 4HQPA 4F8HA 5BW2A 4ILAA 4X5TA 4PIRA 4LMKA 5HEHA 4HFHA 3EHZA 4IREA 5J5IA 4FRRA 5AFLA 2XQ5A 3TLVA 5HEJA 2Y54A 3UQ4A 3UU6A 4A98A 2PH9A 5AFKA 5BRXA 4AFTA 4QAAA 2YOEA 5KE4A 3SQ9A 3WTHA 4ZZCA 1UX2A 3C79A 5J5FA 3TLUA 4TNVA 2UZ6A 2XQ7A 2YKSA 4QH5A 5HCJA 2XQ8A 1I9BA 4Z91A 2BYQA 2BG9A 5HEOA 2BYRA 5AFNA 5CFBA 3TLSA 2X00D 4ZZBA 3TLWA 2W8FA 2ZJVA 3C84A 4TWHA 5L4HA 2WNJA 3UU4A 3WTJA 5J5HA 3UUBA 3PMZA 4ZRUA 3T4MA 4DBMA 4A97A 2WN9A 5AINA 4TWDA 4QABA 4HFEA 3LSVA 3WTNA 3U8NA 5L47A 2XQ9A 4ILCA 2BG9C
chains in the Genus database with same CATH superfamily
2QC1B 4BFQA 4AFHA 2ZJUA 4HFIA 4LMJA 3U8JA 3ZKRA 2Y7YA 3WTOA 4UM1A 4LMLA 2YMDA 3UU5A 4AFGA 3ZDGA 2XNTA 2W8GA 3U8LA 3RQUA 3U8MA 4COFA 1UW6A 2Y58A 4HFBA 1UV6A 3EI0A 4UXUA 3UU3A 3WTKA 4HFDA 3SH1A 2BG9E 4QACA 3WTLA 4XK9A 3RIFA 4ZR6A 4B5DA 2C9TA 2XYSA 2Y56A 3JADA 5KZUA 4IL9A 2XYTA 5J5GA 5AFHA 4UM3P 4ZJSA 5BP0A 4NPPA 2WNLA 5FJVA 2BYNA 4HFCA 5CO5A 3U8KA 3ZDHA 4ALXA 2BYPA 3RHWA 2XQAA 5IUXA 3WTMA 3WIPA 3SQ6A 2WZYA 4Z90A 5LXBA 2PGZA 2YMEA 5J0ZA 3RQWA 2XQ6A 4TWFA 4EZ1A 4IL4A 5AFJA 5AFMB 2YN6A 2XNUA 2BG9B 3P4WA 3RIAA 3RI5A 4NZBA 2XZ5A 2XQ4A 2BR7A 2XNVA 2BR8A 5HCMA 4UY2A 2X00A 4ZJTA 4BQTA 4XHEA 5HEUA 3GUAA 3IGQA 4UM3A 5LG3A 4QH1A 2BYSA 2XQ3A 3UU8A 5TVCA 3PEOA 4QH4A 5HEGA 4TNWA 5JMEA 3EAMA 3JAFA 4ZK1A 3P50A 5AFMA 4D01A 4ILBA 2Y57A 5SYOA 3UQ7A 2WNCA 3TLTA 2VL0A 2BJ0A 3WTIA 4ZK4A 4UM3S 5L4EA 4WV9A 3JAEA 3SIOA 2XZ6A 4HQPA 4F8HA 5BW2A 4ILAA 4X5TA 4PIRA 4LMKA 5HEHA 4HFHA 3EHZA 4IREA 5J5IA 4FRRA 5AFLA 2XQ5A 3TLVA 5HEJA 2Y54A 3UQ4A 3UU6A 4A98A 2PH9A 5AFKA 5BRXA 4AFTA 4QAAA 2YOEA 5KE4A 3SQ9A 3WTHA 4ZZCA 1UX2A 3C79A 5J5FA 3TLUA 4TNVA 2UZ6A 2XQ7A 2YKSA 4QH5A 5HCJA 2XQ8A 1I9BA 4Z91A 2BYQA 2BG9A 5HEOA 2BYRA 5AFNA 5CFBA 3TLSA 2X00D 4ZZBA 3TLWA 2W8FA 2ZJVA 3C84A 4TWHA 5L4HA 2WNJA 3UU4A 3WTJA 5J5HA 3UUBA 3PMZA 4ZRUA 3T4MA 4DBMA 4A97A 2WN9A 5AINA 4TWDA 4QABA 4HFEA 3LSVA 3WTNA 3U8NA 5L47A 2XQ9A 4ILCA 2BG9C
chains in the Genus database with same CATH topology
2QC1B 4BFQA 4AFHA 2ZJUA 4HFIA 4LMJA 3U8JA 3ZKRA 2Y7YA 3WTOA 4UM1A 4LMLA 2YMDA 3UU5A 4AFGA 3ZDGA 2XNTA 2W8GA 3U8LA 3RQUA 3U8MA 4COFA 1UW6A 2Y58A 4HFBA 1UV6A 3EI0A 4UXUA 3UU3A 3WTKA 4HFDA 3SH1A 2BG9E 4QACA 3WTLA 4XK9A 3RIFA 4ZR6A 4B5DA 2C9TA 2XYSA 2Y56A 3JADA 5KZUA 4IL9A 2XYTA 5J5GA 5AFHA 4UM3P 4ZJSA 5BP0A 4NPPA 2WNLA 5FJVA 2BYNA 4HFCA 5CO5A 3U8KA 3ZDHA 4ALXA 2BYPA 3RHWA 2XQAA 5IUXA 3WTMA 3WIPA 3SQ6A 2WZYA 4Z90A 5LXBA 2PGZA 2YMEA 5J0ZA 3RQWA 2XQ6A 4TWFA 4EZ1A 4IL4A 5AFJA 5AFMB 2YN6A 2XNUA 2BG9B 3P4WA 3RIAA 3RI5A 4NZBA 2XZ5A 2XQ4A 2BR7A 2XNVA 2BR8A 5HCMA 4UY2A 2X00A 4ZJTA 4BQTA 4XHEA 5HEUA 3GUAA 3IGQA 4UM3A 5LG3A 4QH1A 2BYSA 2XQ3A 3UU8A 5TVCA 3PEOA 4QH4A 5HEGA 4TNWA 5JMEA 3EAMA 3JAFA 4ZK1A 3P50A 5AFMA 4D01A 4ILBA 2Y57A 5SYOA 3UQ7A 2WNCA 3TLTA 2VL0A 2BJ0A 3WTIA 4ZK4A 4UM3S 5L4EA 4WV9A 3JAEA 3SIOA 2XZ6A 4HQPA 4F8HA 5BW2A 4ILAA 4X5TA 4PIRA 4LMKA 5HEHA 4HFHA 3EHZA 4IREA 5J5IA 4FRRA 5AFLA 2XQ5A 3TLVA 5HEJA 2Y54A 3UQ4A 3UU6A 4A98A 2PH9A 5AFKA 5BRXA 4AFTA 4QAAA 2YOEA 5KE4A 3SQ9A 3WTHA 4ZZCA 1UX2A 3C79A 5J5FA 3TLUA 4TNVA 2UZ6A 2XQ7A 2YKSA 4QH5A 5HCJA 2XQ8A 1I9BA 4Z91A 2BYQA 2BG9A 5HEOA 2BYRA 5AFNA 5CFBA 3TLSA 2X00D 4ZZBA 3TLWA 2W8FA 2ZJVA 3C84A 4TWHA 5L4HA 2WNJA 3UU4A 3WTJA 5J5HA 3UUBA 3PMZA 4ZRUA 3T4MA 4DBMA 4A97A 2WN9A 5AINA 4TWDA 4QABA 4HFEA 3LSVA 3WTNA 3U8NA 5L47A 2XQ9A 4ILCA 2BG9C
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2QC1 B;  4BFQ A;  4AFH A;  2ZJU A;  4HFI A;  4LMJ A;  3U8J A;  3ZKR A;  2Y7Y A;  3WTO A;  4UM1 A;  4LML A;  2YMD A;  3UU5 A;  4AFG A;  3ZDG A;  2XNT A;  2W8G A;  3U8L A;  3RQU A;  3U8M A;  4COF A;  1UW6 A;  2Y58 A;  4HFB A;  1UV6 A;  3EI0 A;  4UXU A;  3UU3 A;  3WTK A;  4HFD A;  3SH1 A;  2BG9 E;  4QAC A;  3WTL A;  4XK9 A;  3RIF A;  4ZR6 A;  4B5D A;  2C9T A;  2XYS A;  2Y56 A;  3JAD A;  5KZU A;  4IL9 A;  2XYT A;  5J5G A;  5AFH A;  4UM3 P;  4ZJS A;  5BP0 A;  4NPP A;  2WNL A;  5FJV A;  2BYN A;  4HFC A;  5CO5 A;  3U8K A;  3ZDH A;  4ALX A;  2BYP A;  3RHW A;  2XQA A;  5IUX A;  3WTM A;  3WIP A;  3SQ6 A;  2WZY A;  4Z90 A;  5LXB A;  2PGZ A;  2YME A;  5J0Z A;  3RQW A;  2XQ6 A;  4TWF A;  4EZ1 A;  4IL4 A;  5AFJ A;  5AFM B;  2YN6 A;  2XNU A;  2BG9 B;  3P4W A;  3RIA A;  3RI5 A;  4NZB A;  2XZ5 A;  2XQ4 A;  2BR7 A;  2XNV A;  2BR8 A;  5HCM A;  4UY2 A;  2X00 A;  4ZJT A;  4BQT A;  4XHE A;  5HEU A;  3GUA A;  3IGQ A;  4UM3 A;  5LG3 A;  4QH1 A;  2BYS A;  2XQ3 A;  3UU8 A;  5TVC A;  3PEO A;  4QH4 A;  5HEG A;  4TNW A;  5JME A;  3EAM A;  3JAF A;  4ZK1 A;  3P50 A;  5AFM A;  4D01 A;  4ILB A;  2Y57 A;  5SYO A;  3UQ7 A;  2WNC A;  3TLT A;  2VL0 A;  2BJ0 A;  3WTI A;  4ZK4 A;  4UM3 S;  5L4E A;  4WV9 A;  3JAE A;  3SIO A;  2XZ6 A;  4HQP A;  4F8H A;  5BW2 A;  4ILA A;  4X5T A;  4PIR A;  4LMK A;  5HEH A;  4HFH A;  3EHZ A;  4IRE A;  5J5I A;  4FRR A;  5AFL A;  2XQ5 A;  3TLV A;  5HEJ A;  2Y54 A;  3UQ4 A;  3UU6 A;  4A98 A;  2PH9 A;  5AFK A;  5BRX A;  4AFT A;  4QAA A;  2YOE A;  5KE4 A;  3SQ9 A;  3WTH A;  4ZZC A;  1UX2 A;  3C79 A;  5J5F A;  3TLU A;  4TNV A;  2UZ6 A;  2XQ7 A;  2YKS A;  4QH5 A;  5HCJ A;  2XQ8 A;  1I9B A;  4Z91 A;  2BYQ A;  2BG9 A;  5HEO A;  2BYR A;  5AFN A;  5CFB A;  3TLS A;  2X00 D;  4ZZB A;  3TLW A;  2W8F A;  2ZJV A;  3C84 A;  4TWH A;  5L4H A;  2WNJ A;  3UU4 A;  3WTJ A;  5J5H A;  3UUB A;  3PMZ A;  4ZRU A;  3T4M A;  4DBM A;  4A97 A;  2WN9 A;  5AIN A;  4TWD A;  4QAB A;  4HFE A;  3LSV A;  3WTN A;  3U8N A;  5L47 A;  2XQ9 A;  4ILC A;  2BG9 C; 
#chains in the Genus database with same CATH topology
 2QC1 B;  4BFQ A;  4AFH A;  2ZJU A;  4HFI A;  4LMJ A;  3U8J A;  3ZKR A;  2Y7Y A;  3WTO A;  4UM1 A;  4LML A;  2YMD A;  3UU5 A;  4AFG A;  3ZDG A;  2XNT A;  2W8G A;  3U8L A;  3RQU A;  3U8M A;  4COF A;  1UW6 A;  2Y58 A;  4HFB A;  1UV6 A;  3EI0 A;  4UXU A;  3UU3 A;  3WTK A;  4HFD A;  3SH1 A;  2BG9 E;  4QAC A;  3WTL A;  4XK9 A;  3RIF A;  4ZR6 A;  4B5D A;  2C9T A;  2XYS A;  2Y56 A;  3JAD A;  5KZU A;  4IL9 A;  2XYT A;  5J5G A;  5AFH A;  4UM3 P;  4ZJS A;  5BP0 A;  4NPP A;  2WNL A;  5FJV A;  2BYN A;  4HFC A;  5CO5 A;  3U8K A;  3ZDH A;  4ALX A;  2BYP A;  3RHW A;  2XQA A;  5IUX A;  3WTM A;  3WIP A;  3SQ6 A;  2WZY A;  4Z90 A;  5LXB A;  2PGZ A;  2YME A;  5J0Z A;  3RQW A;  2XQ6 A;  4TWF A;  4EZ1 A;  4IL4 A;  5AFJ A;  5AFM B;  2YN6 A;  2XNU A;  2BG9 B;  3P4W A;  3RIA A;  3RI5 A;  4NZB A;  2XZ5 A;  2XQ4 A;  2BR7 A;  2XNV A;  2BR8 A;  5HCM A;  4UY2 A;  2X00 A;  4ZJT A;  4BQT A;  4XHE A;  5HEU A;  3GUA A;  3IGQ A;  4UM3 A;  5LG3 A;  4QH1 A;  2BYS A;  2XQ3 A;  3UU8 A;  5TVC A;  3PEO A;  4QH4 A;  5HEG A;  4TNW A;  5JME A;  3EAM A;  3JAF A;  4ZK1 A;  3P50 A;  5AFM A;  4D01 A;  4ILB A;  2Y57 A;  5SYO A;  3UQ7 A;  2WNC A;  3TLT A;  2VL0 A;  2BJ0 A;  3WTI A;  4ZK4 A;  4UM3 S;  5L4E A;  4WV9 A;  3JAE A;  3SIO A;  2XZ6 A;  4HQP A;  4F8H A;  5BW2 A;  4ILA A;  4X5T A;  4PIR A;  4LMK A;  5HEH A;  4HFH A;  3EHZ A;  4IRE A;  5J5I A;  4FRR A;  5AFL A;  2XQ5 A;  3TLV A;  5HEJ A;  2Y54 A;  3UQ4 A;  3UU6 A;  4A98 A;  2PH9 A;  5AFK A;  5BRX A;  4AFT A;  4QAA A;  2YOE A;  5KE4 A;  3SQ9 A;  3WTH A;  4ZZC A;  1UX2 A;  3C79 A;  5J5F A;  3TLU A;  4TNV A;  2UZ6 A;  2XQ7 A;  2YKS A;  4QH5 A;  5HCJ A;  2XQ8 A;  1I9B A;  4Z91 A;  2BYQ A;  2BG9 A;  5HEO A;  2BYR A;  5AFN A;  5CFB A;  3TLS A;  2X00 D;  4ZZB A;  3TLW A;  2W8F A;  2ZJV A;  3C84 A;  4TWH A;  5L4H A;  2WNJ A;  3UU4 A;  3WTJ A;  5J5H A;  3UUB A;  3PMZ A;  4ZRU A;  3T4M A;  4DBM A;  4A97 A;  2WN9 A;  5AIN A;  4TWD A;  4QAB A;  4HFE A;  3LSV A;  3WTN A;  3U8N A;  5L47 A;  2XQ9 A;  4ILC A;  2BG9 C; 
#chains in the Genus database with same CATH homology
 2QC1 B;  4BFQ A;  4AFH A;  2ZJU A;  4HFI A;  4LMJ A;  3U8J A;  3ZKR A;  2Y7Y A;  3WTO A;  4UM1 A;  4LML A;  2YMD A;  3UU5 A;  4AFG A;  3ZDG A;  2XNT A;  2W8G A;  3U8L A;  3RQU A;  3U8M A;  4COF A;  1UW6 A;  2Y58 A;  4HFB A;  1UV6 A;  3EI0 A;  4UXU A;  3UU3 A;  3WTK A;  4HFD A;  3SH1 A;  2BG9 E;  4QAC A;  3WTL A;  4XK9 A;  3RIF A;  4ZR6 A;  4B5D A;  2C9T A;  2XYS A;  2Y56 A;  3JAD A;  5KZU A;  4IL9 A;  2XYT A;  5J5G A;  5AFH A;  4UM3 P;  4ZJS A;  5BP0 A;  4NPP A;  2WNL A;  5FJV A;  2BYN A;  4HFC A;  5CO5 A;  3U8K A;  3ZDH A;  4ALX A;  2BYP A;  3RHW A;  2XQA A;  5IUX A;  3WTM A;  3WIP A;  3SQ6 A;  2WZY A;  4Z90 A;  5LXB A;  2PGZ A;  2YME A;  5J0Z A;  3RQW A;  2XQ6 A;  4TWF A;  4EZ1 A;  4IL4 A;  5AFJ A;  5AFM B;  2YN6 A;  2XNU A;  2BG9 B;  3P4W A;  3RIA A;  3RI5 A;  4NZB A;  2XZ5 A;  2XQ4 A;  2BR7 A;  2XNV A;  2BR8 A;  5HCM A;  4UY2 A;  2X00 A;  4ZJT A;  4BQT A;  4XHE A;  5HEU A;  3GUA A;  3IGQ A;  4UM3 A;  5LG3 A;  4QH1 A;  2BYS A;  2XQ3 A;  3UU8 A;  5TVC A;  3PEO A;  4QH4 A;  5HEG A;  4TNW A;  5JME A;  3EAM A;  3JAF A;  4ZK1 A;  3P50 A;  5AFM A;  4D01 A;  4ILB A;  2Y57 A;  5SYO A;  3UQ7 A;  2WNC A;  3TLT A;  2VL0 A;  2BJ0 A;  3WTI A;  4ZK4 A;  4UM3 S;  5L4E A;  4WV9 A;  3JAE A;  3SIO A;  2XZ6 A;  4HQP A;  4F8H A;  5BW2 A;  4ILA A;  4X5T A;  4PIR A;  4LMK A;  5HEH A;  4HFH A;  3EHZ A;  4IRE A;  5J5I A;  4FRR A;  5AFL A;  2XQ5 A;  3TLV A;  5HEJ A;  2Y54 A;  3UQ4 A;  3UU6 A;  4A98 A;  2PH9 A;  5AFK A;  5BRX A;  4AFT A;  4QAA A;  2YOE A;  5KE4 A;  3SQ9 A;  3WTH A;  4ZZC A;  1UX2 A;  3C79 A;  5J5F A;  3TLU A;  4TNV A;  2UZ6 A;  2XQ7 A;  2YKS A;  4QH5 A;  5HCJ A;  2XQ8 A;  1I9B A;  4Z91 A;  2BYQ A;  2BG9 A;  5HEO A;  2BYR A;  5AFN A;  5CFB A;  3TLS A;  2X00 D;  4ZZB A;  3TLW A;  2W8F A;  2ZJV A;  3C84 A;  4TWH A;  5L4H A;  2WNJ A;  3UU4 A;  3WTJ A;  5J5H A;  3UUB A;  3PMZ A;  4ZRU A;  3T4M A;  4DBM A;  4A97 A;  2WN9 A;  5AIN A;  4TWD A;  4QAB A;  4HFE A;  3LSV A;  3WTN A;  3U8N A;  5L47 A;  2XQ9 A;  4ILC A;  2BG9 C; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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