2BRWA

Crystal structure of streptococcus pneumoniae hyaluronate lyase from 30percent pegmme.
Total Genus 247
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
247
sequence length
721
structure length
721
Chain Sequence
VKDTYTDRLDDWNGIIAGNQYYDSKNDQMAKLNQELEGKVADSLSSISSQADRIYLWEKFSNYKTSANLTATYRKLEEMAKQVTNPSSRYYQDETVVRTVRDSMEWMHKHVYNSEKSIVGNWWDYEIGTPRAINNTLSLMKEYFSDEEIKKYTDVIEKFVPDPEHFRKTTDNPFKALGGNLVDMGRVKVIAGLLRKDDQEISSTIRSIEQVFKLVDQGEGFYQDGSYIDHTNVAYTGAYGNVLIDGLSQLLPVIQKTKNPIDKDKMQTMYHWIDKSFAPLLVNGELMDMSRGRSISRANSEGHVAAVEVLRGIHRIADMSEGETKQRLQSLVKTIVQSDSYYDVFKNLKTYKDISLMQSLLSDAGVASVPRTSYLSAFNKMDKTAMYNAEKGFGFGLSLFSSRTLNYEHMNKENKRGWYTSDGMFYLYNGDLSHYSDGYWPTVNPYKMPGTTETDAKRADSDTGKVLPSAFVGTSKLDDANATATMDFTNWNQTLTAHKSWFMLKDKIAFLGSNIQNTSTDTAATTIDQRKLESSNPYKVYVNDKEASLTEQEKDYPETQSVFLESSDSKKNIGYFFFKKSSISMSKALQKGAWKDINEGQSDKEVENEFLTISQAHKQNGDSYGYMLIPNVDRATFNQMIKELESSLIENNETLQSVYDAKQGVWGIVKYDDSVSTISNQFQVLKRGVYTIRKEGDEYKIAYYNPETQESAPDQEVFKKL
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule keywords HYALURONATE LYASE
publication title Alternate Structural Conformations of Streptococcus Pneumoniae Hyaluronan Lyase: Insights Into Enzyme Flexibility and Underlying Molecular Mechanism of Action.
pubmed doi rcsb
source organism Streptococcus pneumoniae
molecule tags Lyase
total genus 247
structure length 721
sequence length 721
chains with identical sequence B
ec nomenclature ec 4.2.2.1: Hyaluronate lyase.
pdb deposition date 2005-05-11

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02278 Lyase_8 Polysaccharide lyase family 8, super-sandwich domain
A PF02884 Lyase_8_C Polysaccharide lyase family 8, C-terminal beta-sandwich domain
A PF08124 Lyase_8_N Polysaccharide lyase family 8, N terminal alpha-helical domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.50.10.100 Mainly Alpha Alpha/alpha barrel Glycosyltransferase Chondroitin AC/alginate lyase 2brwA01
2.60.220.10 Mainly Beta Sandwich Chondroitinase Ac; Chain A, domain 3 Polysaccharide lyase family 8-like, C-terminal 2brwA03
2.70.98.10 Mainly Beta Distorted Sandwich Beta-galactosidase; Chain A, domain 5 Beta-galactosidase; Chain A, domain 5 2brwA02
3T2QA 3T2PA 1F4AA 1MMYA 3NNBA 4BZFA 4D6CA 1HM3A 3NJVA 1EGUA 2WMIA 1PX4A 3IAQA 1JZ2A 1JZ6A 1HN0A 2BRPA 3SEPA 1J0NA 2WMIB 4OJZA 3OS7A 1OJNA 4D6GA 1N7QA 1F9GA 1K1WA 1NSXA 3VD9A 1RWHA 2E22A 1NS0A 1ULVA 1HV6A 3T0DA 2WMJA 4E1YA 1OJPA 1NSRA 1LXKA 1L7KA 3VD7A 4F13A 2WVXA 3A0OA 1NS8A 1SO0A 2ZQ0A 4BZHA 4D6HA 2WVXB 3E7JA 2X03A 1HMUA 5JMDA 2WDAA 2Q1FA 3Q1NA 3VSNA 2WVYA 1OJOA 2WW1A 1PX3A 2JKEA 1MMUA 1JZ3A 4D6EA 2WW3A 1MMXA 2BRWA 1NS2A 1I8QA 1N7PA 1JYWA 4D6JA 1LF9A 3T08A 1JOVA 1J0MA 4BZEA 1NS4A 1MMZA 3I3EA 1RWFA 1YGAA 3A24A 3K25A 3DECA 3VD3A 3MUZ1 1YQ2A 1F4HA 3WFAA 4AQ0A 1RW9A 4D6DA 3CZJA 1CB8A 1N7NA 3MWXA 3VDCA 3T09A 2WCOA 1RWGA 3BGAA 4DUXA 2CISA 4OK2A 2JKPA 2HTAA 3OBAA 3MUY1 4MMHA 2WMKA 3IMHA 1HM2A 3NREA 3E80A 1K1XA 1F1SA 1NSMA 1MN0A 1SNZA 1LF6A 1LOHA 1JYNA 1C82A 2FUTA 2D73A 3T0AA 2WMFA 1X1JA 1N7OA 1JZ5A 1JZ4A 5JMFA 1NSZA 2CIQA 1NSVA 4FNVA 4D71A 1JYVA 3T0BA 1RWAA 2CIRA 3E1F1 3DYPA 3MV01 4OK4A 1NS7A 3J7HA 4DUWA 2WVZA 3OB8A 1HMWA 2WMGA 2WW2A 2XSGA 1LXMA 2E24A 1K1YA 4TTGA 1DP0A 1X1HA 3MV11 1X1IA 4RNLA 3DYMA 5A1AA 1HN1A 3NJXA 3VD4A 2WMHA 4NEIA 4OZVA 4D6FA 1JYXA 1NKGA 3DYOA 3VDBA 1NSSA 3VSMA 1Z45A 1W3YA 3NFVA 2BRVX 3I3BA 2HTBA 3T2OA 2FUQA 1TXKA 4DUVA 2ZXQA 4OZWA 2XHNA 3VDAA 4BZGA 1JZ7A 3IAPA 4D72A 4F10A 3I3DA 3DCDA 1RWCA 2JKAA 4D6IA 1UG9A 1JZ8A 1N7RA 1L7JA 1OJMA 2WZSA 5E1QA 1LURA 1NSUA 4MMIA 3VD5A 1QAZA 3AFLA 3ECQA 2WW0A
chains in the Genus database with same CATH superfamily
3T2QA 3T2PA 4D6CA 3NJVA 3HXDB 4DOEA 1JZ6A 2WYHA 2YFOA 2BRPA 1IVVA 2WINB 1J0NA 2RI9A 3K5TA 1OJNA 4AYRA 4D6GA 3D5SA 1K1WA 5CD2A 3D4ZA 4KFFA 3M7BA 1TN8B 3RRSA 2WGQA 2WMJA 2R2LB 5CZLA 1FBWA 3VXDA 1NSRA 1QAFA 3DX1A 3HXFB 4GTPB 1LXKA 1L7KA 2CFLA 1NS8A 1SO0A 3ACSA 3EUVB 2GOXA 2C10A 2F7QA 1QWNA 2WVXB 4BTYA 2WIIB 3DDFA 5GZKA 1HMUA 4BOKA 2Q1FA 3KSLB 2A73B 3EQAA 3RX8A 3Q1NA 2XQWA 3SDUA 3BVWA 1JZ3A 4D6EA 4TXTA 2H6GB 1NS2A 2YX9A 2WY8A 1N7PA 3WVFA 2WY7A 3CU7A 4M76A 4CJ1A 1JOVA 2B39A 4BOJA 2XFGA 1RWFA 2F6DA 3A24A 1QALA 3K25A 3EJQA 3AMOB 3VD3A 4ZH5A 2J5CA 1O6QA 3M71A 1RW9A 4KFDA 1SPUA 3DX3A 3MWXA 3QT9A 2CISA 3PQIA 4J5TA 4OK2A 2HTAA 3OBAA 1WZZA 1G6IA 3X40A 2XWJB 3H2WA 3KIIA 3DX0A 1SNZA 2FV0A 1LF6A 3M7CA 3DSUB 1KFGA 2G02A 1IA6A 4KKIA 5IL3A 3CZNA 3WKGA 2NVPA 2EACA 1JZ4A 1NSZA 1JS4A 2PN5A 2CFKA 3BVXA 2OOVA 1RWAA 1V5DA 1JYVA 3E1F1 1R76A 1VD5A 2NOJA 1L2AA 2AHGA 3HXCB 1XW2A 3BVTA 4DUWA 1IQXA 5E2JA 2WVZA 3M73A 3PYBA 1GLMA 1H37A 2DRSA 4LNGB 2WW2A 2F1AA 2F7PA 1F9DA 3WKIA 3WIRA 3DSVB 1GAHA 4GTVB 1R33A 3X42A 1N94B 2CG1A 2DRRA 3DYMA 5A1AA 3NJXA 3MI6A 3M01A 3M77A 5EASA 2GH4A 1WMPA 2VN4A 3DYOA 1IVXA 3EU5B 4GTQB 2Y74A 3T2OA 1S64B 3W5NA 1JZ7A 2P0VA 4BZGA 1HXAA 4GTMB 1KRFA 1NI1B 3I3DA 1O1RB 1LD7B 3Q75B 1C3DA 3DDGA 2WOHA 3LVTA 3EJTA 1GXNA 5JPMB 1D8DB 5M7YA 4D4DA 3W7SA 1SA5B 1NL4B 3SFXB 1DL2A 1OJMA 5ILYA 3QXFA 1H36A 4ONTA 1D8EB 5E1QA 4D4CA 1NSUA 1W5ZA 5MEHA 5IK6A 3BLBA 3W7WA 3BUPA 2WW0A 2F7OA 3RJ3A 1O7DD 1W6CA 5IM1A 3NNBA 4BZFA 1WMOA 3KQ4A 3K7XA 3TF4A 3D50A 3D5RA 2XN0A 2WMIA 4FNSA 1HN0A 2W0QA 2JF4A 1W4NA 3SEPA 1RKYA 3RX5A 1XWQA 1KZPB 4OJZA 4Z4JA 2XN1A 1F9GA 1N7QA 4AYPA 1NSXA 2E22A 2OKXA 1FCEA 2ZL8A 3T0DA 3W7TA 2EADA 3LOYA 3D51A 4FNTA 5KBPA 2D5JA 1TQWA 3X17A 2G0DA 2ZQ0A 4BZHA 3QPFA 4D6HA 4BTXA 1OACA 3WA3A 2X03A 1TU5A 2OW7A 1FPPB 5JMDA 3G4FA 3HI7A 4BTWA 3HXBB 1MMUA 1PS3A 1AV4A 2BRWA 1MMXA 4FNUA 1GSZA 3M7EA 4AYOA 3W7XA 3OXUA 2CQSA 3DSXB 1JYWA 1FO2A 1LF9A 3M75A 4L9PB 1FO3A 4GL3A 3CZSA 1NS4A 1MMZA 1KZOB 2ZISB 1W6KA 3S4DA 3LZ9A 3WFAA 3HIIA 5EAUA 4D6DA 1D6UA 3QFYA 3QFZA 1UMPA 3T09A 2V8IA 3N0FA 4GAXA 3RSYA 3UD2A 4KFEA 5CA3A 1W6GA 3NREA 3BUQA 3E80A 1NSMA 1MN0A 3ANKA 1JYNA 3EZ8A 5IL8A 2BBCA 2XWBB 2WMFA 1N7OA 1H3CA 1UI8A 3BVVA 3Q7AB 2CIQA 1NSVA 2CQTA 1NC5A 4D71A 5IK9A 3T0BA 2E2TA 2CFWA 3HXEB 3SDVA 1IVUA 1HXGA 1N4QB 2GZ6A 4L6XA 1IU7A 1NS7A 4WVCA 3P5PA 3OEDA 1IA7A 1RJOA 5AGDA 1HZFA 4TTGA 1JCSB 1N1ZA 3N0GA 3VW5A 3X41A 1FP3A 4ZG8A 2OW6A 1DCEB 1JYXA 1G9JA 1O1TB 4L0GA 2BRVX 1AVKA 2HTBA 4GTRB 4V1RA 1QAKA 1O6RA 3C72B 4YDOB 4DUVA 4OZWA 2XHNA 3G6JB 1GXMA 1TQSA 4KTRA 1QSJA 5GY3A 3DX2A 3DCDA 1XWTA 2H6IB 1RWCA 2C11A 3SDRA 2Y73A 3NBBA 3DX4A 4D6IA 1JZ8A 3PZ4B 4JJJA 5C05A 3EJSA 2V8JA 4GTSB 2FV1A 4C1SA 4EL8A 3SX1A 2AFAA 3SQCA 3BVUA 2F18A 4GTTB 1SA4B 2D73A 1F9OA 1H3AA 2JG0A 5ILIA 1MZCB 1F4AA 1HWWA 2CFDA 3SDTA 2B4FA 4YDEB 1EGUA 4DI5A 1PX4A 3WA2X 2H6FB 3DSTB 1L1YA 4GTOB 1AYXA 3PZ3B 1SQCA 2WMIB 2BT3A 2D1WA 4K3AA 3OS7A 2E2UA 5ILZA 3M7LA 1N24A 2F7RA 1NXCA 1TNBB 3QWTA 3VD9A 1WU4A 2V3PA 1GHQA 1NS0A 1H12A 3NBJA 2EABA 1FBOA 1N20A 5FOBB 1QBQB 1R34A 1OJPA 4LNBB 2ONHA 3TY1A 4D94A 3SAEA 2PNCA 2BB5A 4F13A 4EV2A 1HCUA 1LTXB 2I07B 3PZ1B 4FNPA 1FT1B 2WVYA 2WW1A 2ZIRB 5FO8B 3E30B 5KKBA 1O79A 2XN2A 2PMVA 4RNQA 3WC3A 3W5MA 1DYUA 3ANIA 3KN4A 4D6JA 3N9HA 1N21A 4BZEA 3DPYB 1FMIA 1YGAA 4UFCA 1W7CA 3DECA 3WIWA 4ZH1A 3M00A 4AYQA 1AVLA 5DGQA 1V7XA 3BUDA 4FUSA 1CB8A 1N7NA 1UI7A 4MU9A 1K72A 3EU8A 4FXKB 1TQUA 2WCOA 2ZBLA 3BGAA 4DUXA 1JCRB 2Z07A 1LVNA 2JKPA 4FNRA 4ZRPA 2OQEC 1F1SA 4TF4A 1HTYA 2V8KA 1LOHA 1C82A 2FUTA 1S63B 4D8OA 3T0AA 3E6UA 1GA2A 1X1JA 3PMMA 1JZ5A 3M74A 3K11A 5DHKA 1UT9A 1WMNA 1TQTA 4FNVA 3KLSA 3DRAB 1H39A 2BB6A 3Q7FB 4Q2BA 2CWVA 3DYPA 2QNOA 3MV01 1V5CA 4OK4A 1IQYA 3E32B 2IEJB 3J7HA 3OB8A 2JJBA 2YIKA 3WIQA 3GT5A 5JPNB 3W7UA 2XSGA 3G4DA 1FAEA 1LXMA 1TN6B 1N22A 1K1YA 3ACTA 1H54A 2FBAA 1TNUB 1JCQB 3MV11 1WU5A 1LD8B 1N4RB 1X1IA 1GXOA 1KREA 1TN7B 3KSQB 3VD4A 3CIHA 2WYNA 2WMHA 3BUBA 3BLCA 3VDBA 3RX7A 3MPHA 4FXGB 1NSSA 1N95B 1W3YA 3ANJA 3NFVA 3E37B 4D4AA 1N9EA 1AGMA 1SIIA 4D1JA 1KSIA 3PYAA 1TXKA 3CV5A 2DRQA 3DSSB 2ZXQA 3S4BA 3HIGA 3VDAA 3IAPA 1FT2B 1W6JA 3ON6A 4D72A 1V7WA 2H6HB 3X3ZA 4F10A 2ALWA 5DHIA 1CEMA 5IKAA 2A8ZA 3T33A 1W2ZA 1UG9A 1A2VA 2WOFA 2RGKA 3QT3A 1V7VA 1N7RA 2DROA 3QXQA 1L7JA 5IK0A 2EAEA 1LURA 4MMIA 3EJUA 3VD5A 1N4PB 1QAZA 5FO9B 3AFLA 3ECQA 3T0UA 2SQCA 2VN7A 2BEDB 1IVWA 3SFYB 1JRQA 1MMYA 1HM3A 2FUZA 3Q73B 5EATA 3A3VA 4WVBA 3IAQA 2RI8A 1JZ2A 4XUVA 1KSCA 3EJRA 3GZKA 4FNQA 3E73A 1N1BA 3WUXA 1CLCA 2FYVA 3Q78B 1RWHA 4V1SA 4D4BA 1ULVA 1HV6A 1QWUA 4E1YA 3U7VA 4CJ0A 4EV5A 3ALAA 4LIXA 1H3BA 3VD7A 1N4SB 2WVXA 3A0OA 1X81B 5ILDA 3SXXA 4LNVA 3E7JA 4FJQA 4KTPA 5DGRA 3SDQA 2WDAA 4WU0A 3VSNA 1OJOA 1PX3A 2JKEA 2OQEA 2WW3A 3PGBA 1HXKA 1KS8A 1I8QA 5M7IA 4DODA 3X3YA 1D6ZA 1KKTA 1G87A 3QRYA 1TQVA 3X3XA 3T08A 1KWFA 1TNYB 4Z4LA 1J0MA 3D4YA 3QR8A 2D8LA 3E34B 3RENA 3KBUC 4QT9A 1DOGA 1US1A 4CE7A 3AMOA 3I3EA 3M78A 1IS9A 3WKHA 1EKMA 1YQ2A 1F4HA 3MUZ1 4AQ0A 3F59A 3UD1A 3CZJA 3VDCA 3E33B 4EHMB 3EJPA 3GLYA 1RWGA 5ILHA 3D3IA 3QG0A 2RDYA 1PU4A 1H13A 3PZ2B 3MUY1 4MMHA 1O1SB 3S9VA 2WMKA 1HM2A 3IMHA 1K1XA 3KBTC 2ONGA 3QDEA 5JMFA 5ILKA 1SIHA 2AHFA 3P2CA 2CIRA 2CWUA 1HMWA 1QX1A 2WMGA 1N23A 2E2VA 3P5RA 2E24A 1DP0A 1TNZB 1O6HA 1X1HA 3WKFA 4YCRA 4RNLA 4Q88A 1RQ5A 3S4CA 3QSPA 4MBGB 2KXSA 1HN1A 3BS6A 3M02A 2V3NA 1H35A 4NEIA 4OZVA 5IKHA 4D6FA 1NKGA 5FO7B 3VSMA 2F1BA 1Z45A 3H7LA 3I3BA 3Q79B 1N9AB 4DLOA 2FUQA 3S4AA 3AFJA 4ZRQA 1GAIA 2CFGA 3BUIA 2WO0A 1HXCA 3H3KA 1TNOB 2OOVC 2KXRA 1O5MB 4D1IA 2YFNA 3M72A 4KKJA 1WU6A 3M76A 5GW7A 3D52A 2JKAA 2CWTA 5ILJA 1QQFA 2WYIA 1H14A 4DLQA 3DSWB 2WZSA 1D6YA 2F0YB 4K35A 1HX9A 2CG0A 1X9DA 1TF4A 1KSDA 1G9GA 4WVAA 2ZZRA
chains in the Genus database with same CATH topology
3T2QA 3T2PA 1F4AA 1MMYA 3NNBA 4BZFA 4D6CA 1HM3A 3NJVA 1EGUA 2WMIA 1PX4A 3IAQA 1JZ2A 1JZ6A 1HN0A 2BRPA 3SEPA 1J0NA 2WMIB 4OJZA 3OS7A 1OJNA 4D6GA 1N7QA 1F9GA 1K1WA 1NSXA 3VD9A 1RWHA 2E22A 1NS0A 1ULVA 1HV6A 3T0DA 2WMJA 4E1YA 1OJPA 3TY1A 1NSRA 1LXKA 1L7KA 3VD7A 4F13A 2WVXA 3A0OA 1NS8A 1SO0A 2ZQ0A 4BZHA 4D6HA 2WVXB 3E7JA 2X03A 1HMUA 5JMDA 2WDAA 2Q1FA 3Q1NA 3VSNA 2WVYA 1OJOA 2WW1A 1PX3A 2JKEA 1MMUA 1JZ3A 4D6EA 2WW3A 1MMXA 2BRWA 1NS2A 1I8QA 1N7PA 3WVFA 1JYWA 4D6JA 1LF9A 3T08A 1JOVA 1J0MA 4BZEA 1NS4A 1MMZA 3I3EA 1RWFA 1YGAA 3A24A 3K25A 3DECA 3VD3A 3MUZ1 1YQ2A 1F4HA 3WFAA 4AQ0A 1RW9A 4D6DA 3CZJA 1CB8A 1N7NA 3MWXA 3VDCA 3T09A 2WCOA 1RWGA 3BGAA 4DUXA 2CISA 4OK2A 2JKPA 2HTAA 3OBAA 4J5TA 3MUY1 4MMHA 2WMKA 3IMHA 1HM2A 3NREA 3E80A 1K1XA 1F1SA 1NSMA 1MN0A 1SNZA 1LF6A 1LOHA 1JYNA 1C82A 2FUTA 2D73A 3T0AA 2WMFA 1X1JA 1N7OA 1JZ5A 1JZ4A 5JMFA 1NSZA 2CIQA 1NSVA 4FNVA 4D71A 1JYVA 3T0BA 1RWAA 2CIRA 3E1F1 3DYPA 3MV01 4OK4A 1NS7A 3J7HA 4DUWA 2WVZA 3OB8A 1HMWA 2WMGA 2WW2A 2XSGA 1LXMA 2E24A 1K1YA 4TTGA 1DP0A 1X1HA 3MV11 1X1IA 4RNLA 3DYMA 5A1AA 1HN1A 3NJXA 3VD4A 2WMHA 3BS6A 3BLCA 4NEIA 4OZVA 4D6FA 1JYXA 1NKGA 3DYOA 3VDBA 1NSSA 3VSMA 1Z45A 1W3YA 3NFVA 2BRVX 3I3BA 2HTBA 3T2OA 2FUQA 1TXKA 4DUVA 2ZXQA 4OZWA 2XHNA 3VDAA 4BZGA 1JZ7A 3IAPA 4D72A 4F10A 3I3DA 3DCDA 1RWCA 2JKAA 4D6IA 1UG9A 1JZ8A 1N7RA 1L7JA 1OJMA 2WZSA 5E1QA 1LURA 1NSUA 4MMIA 3VD5A 1QAZA 3AFLA 3ECQA 2WW0A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3T2Q A;  3T2P A;  1F4A A;  1MMY A;  3NNB A;  4BZF A;  4D6C A;  1HM3 A;  3NJV A;  1EGU A;  2WMI A;  1PX4 A;  3IAQ A;  1JZ2 A;  1JZ6 A;  1HN0 A;  2BRP A;  3SEP A;  1J0N A;  2WMI B;  4OJZ A;  3OS7 A;  1OJN A;  4D6G A;  1N7Q A;  1F9G A;  1K1W A;  1NSX A;  3VD9 A;  1RWH A;  2E22 A;  1NS0 A;  1ULV A;  1HV6 A;  3T0D A;  2WMJ A;  4E1Y A;  1OJP A;  1NSR A;  1LXK A;  1L7K A;  3VD7 A;  4F13 A;  2WVX A;  3A0O A;  1NS8 A;  1SO0 A;  2ZQ0 A;  4BZH A;  4D6H A;  2WVX B;  3E7J A;  2X03 A;  1HMU A;  5JMD A;  2WDA A;  2Q1F A;  3Q1N A;  3VSN A;  2WVY A;  1OJO A;  2WW1 A;  1PX3 A;  2JKE A;  1MMU A;  1JZ3 A;  4D6E A;  2WW3 A;  1MMX A;  2BRW A;  1NS2 A;  1I8Q A;  1N7P A;  1JYW A;  4D6J A;  1LF9 A;  3T08 A;  1JOV A;  1J0M A;  4BZE A;  1NS4 A;  1MMZ A;  3I3E A;  1RWF A;  1YGA A;  3A24 A;  3K25 A;  3DEC A;  3VD3 A;  3MUZ 1;  1YQ2 A;  1F4H A;  3WFA A;  4AQ0 A;  1RW9 A;  4D6D A;  3CZJ A;  1CB8 A;  1N7N A;  3MWX A;  3VDC A;  3T09 A;  2WCO A;  1RWG A;  3BGA A;  4DUX A;  2CIS A;  4OK2 A;  2JKP A;  2HTA A;  3OBA A;  3MUY 1;  4MMH A;  2WMK A;  3IMH A;  1HM2 A;  3NRE A;  3E80 A;  1K1X A;  1F1S A;  1NSM A;  1MN0 A;  1SNZ A;  1LF6 A;  1LOH A;  1JYN A;  1C82 A;  2FUT A;  2D73 A;  3T0A A;  2WMF A;  1X1J A;  1N7O A;  1JZ5 A;  1JZ4 A;  5JMF A;  1NSZ A;  2CIQ A;  1NSV A;  4FNV A;  4D71 A;  1JYV A;  3T0B A;  1RWA A;  2CIR A;  3E1F 1;  3DYP A;  3MV0 1;  4OK4 A;  1NS7 A;  3J7H A;  4DUW A;  2WVZ A;  3OB8 A;  1HMW A;  2WMG A;  2WW2 A;  2XSG A;  1LXM A;  2E24 A;  1K1Y A;  4TTG A;  1DP0 A;  1X1H A;  3MV1 1;  1X1I A;  4RNL A;  3DYM A;  5A1A A;  1HN1 A;  3NJX A;  3VD4 A;  2WMH A;  4NEI A;  4OZV A;  4D6F A;  1JYX A;  1NKG A;  3DYO A;  3VDB A;  1NSS A;  3VSM A;  1Z45 A;  1W3Y A;  3NFV A;  2BRV X;  3I3B A;  2HTB A;  3T2O A;  2FUQ A;  1TXK A;  4DUV A;  2ZXQ A;  4OZW A;  2XHN A;  3VDA A;  4BZG A;  1JZ7 A;  3IAP A;  4D72 A;  4F10 A;  3I3D A;  3DCD A;  1RWC A;  2JKA A;  4D6I A;  1UG9 A;  1JZ8 A;  1N7R A;  1L7J A;  1OJM A;  2WZS A;  5E1Q A;  1LUR A;  1NSU A;  4MMI A;  3VD5 A;  1QAZ A;  3AFL A;  3ECQ A;  2WW0 A; 
#chains in the Genus database with same CATH topology
 3T2Q A;  3T2P A;  4D6C A;  3NJV A;  3HXD B;  4DOE A;  1JZ6 A;  2WYH A;  2YFO A;  2BRP A;  1IVV A;  2WIN B;  1J0N A;  2RI9 A;  3K5T A;  1OJN A;  4AYR A;  4D6G A;  3D5S A;  1K1W A;  5CD2 A;  3D4Z A;  4KFF A;  3M7B A;  1TN8 B;  3RRS A;  2WGQ A;  2WMJ A;  2R2L B;  5CZL A;  1FBW A;  3VXD A;  1NSR A;  1QAF A;  3DX1 A;  3HXF B;  4GTP B;  1LXK A;  1L7K A;  2CFL A;  1NS8 A;  1SO0 A;  3ACS A;  3EUV B;  2GOX A;  2C10 A;  2F7Q A;  1QWN A;  2WVX B;  4BTY A;  2WII B;  3DDF A;  5GZK A;  1HMU A;  4BOK A;  2Q1F A;  3KSL B;  2A73 B;  3EQA A;  3RX8 A;  3Q1N A;  2XQW A;  3SDU A;  3BVW A;  1JZ3 A;  4D6E A;  4TXT A;  2H6G B;  1NS2 A;  2YX9 A;  2WY8 A;  1N7P A;  3WVF A;  2WY7 A;  3CU7 A;  4M76 A;  4CJ1 A;  1JOV A;  2B39 A;  4BOJ A;  2XFG A;  1RWF A;  2F6D A;  3A24 A;  1QAL A;  3K25 A;  3EJQ A;  3AMO B;  3VD3 A;  4ZH5 A;  2J5C A;  1O6Q A;  3M71 A;  1RW9 A;  4KFD A;  1SPU A;  3DX3 A;  3MWX A;  3QT9 A;  2CIS A;  3PQI A;  4J5T A;  4OK2 A;  2HTA A;  3OBA A;  1WZZ A;  1G6I A;  3X40 A;  2XWJ B;  3H2W A;  3KII A;  3DX0 A;  1SNZ A;  2FV0 A;  1LF6 A;  3M7C A;  3DSU B;  1KFG A;  2G02 A;  1IA6 A;  4KKI A;  5IL3 A;  3CZN A;  3WKG A;  2NVP A;  2EAC A;  1JZ4 A;  1NSZ A;  1JS4 A;  2PN5 A;  2CFK A;  3BVX A;  2OOV A;  1RWA A;  1V5D A;  1JYV A;  3E1F 1;  1R76 A;  1VD5 A;  2NOJ A;  1L2A A;  2AHG A;  3HXC B;  1XW2 A;  3BVT A;  4DUW A;  1IQX A;  5E2J A;  2WVZ A;  3M73 A;  3PYB A;  1GLM A;  1H37 A;  2DRS A;  4LNG B;  2WW2 A;  2F1A A;  2F7P A;  1F9D A;  3WKI A;  3WIR A;  3DSV B;  1GAH A;  4GTV B;  1R33 A;  3X42 A;  1N94 B;  2CG1 A;  2DRR A;  3DYM A;  5A1A A;  3NJX A;  3MI6 A;  3M01 A;  3M77 A;  5EAS A;  2GH4 A;  1WMP A;  2VN4 A;  3DYO A;  1IVX A;  3EU5 B;  4GTQ B;  2Y74 A;  3T2O A;  1S64 B;  3W5N A;  1JZ7 A;  2P0V A;  4BZG A;  1HXA A;  4GTM B;  1KRF A;  1NI1 B;  3I3D A;  1O1R B;  1LD7 B;  3Q75 B;  1C3D A;  3DDG A;  2WOH A;  3LVT A;  3EJT A;  1GXN A;  5JPM B;  1D8D B;  5M7Y A;  4D4D A;  3W7S A;  1SA5 B;  1NL4 B;  3SFX B;  1DL2 A;  1OJM A;  5ILY A;  3QXF A;  1H36 A;  4ONT A;  1D8E B;  5E1Q A;  4D4C A;  1NSU A;  1W5Z A;  5MEH A;  5IK6 A;  3BLB A;  3W7W A;  3BUP A;  2WW0 A;  2F7O A;  3RJ3 A;  1O7D D;  1W6C A;  5IM1 A;  3NNB A;  4BZF A;  1WMO A;  3KQ4 A;  3K7X A;  3TF4 A;  3D50 A;  3D5R A;  2XN0 A;  2WMI A;  4FNS A;  1HN0 A;  2W0Q A;  2JF4 A;  1W4N A;  3SEP A;  1RKY A;  3RX5 A;  1XWQ A;  1KZP B;  4OJZ A;  4Z4J A;  2XN1 A;  1F9G A;  1N7Q A;  4AYP A;  1NSX A;  2E22 A;  2OKX A;  1FCE A;  2ZL8 A;  3T0D A;  3W7T A;  2EAD A;  3LOY A;  3D51 A;  4FNT A;  5KBP A;  2D5J A;  1TQW A;  3X17 A;  2G0D A;  2ZQ0 A;  4BZH A;  3QPF A;  4D6H A;  4BTX A;  1OAC A;  3WA3 A;  2X03 A;  1TU5 A;  2OW7 A;  1FPP B;  5JMD A;  3G4F A;  3HI7 A;  4BTW A;  3HXB B;  1MMU A;  1PS3 A;  1AV4 A;  2BRW A;  1MMX A;  4FNU A;  1GSZ A;  3M7E A;  4AYO A;  3W7X A;  3OXU A;  2CQS A;  3DSX B;  1JYW A;  1FO2 A;  1LF9 A;  3M75 A;  4L9P B;  1FO3 A;  4GL3 A;  3CZS A;  1NS4 A;  1MMZ A;  1KZO B;  2ZIS B;  1W6K A;  3S4D A;  3LZ9 A;  3WFA A;  3HII A;  5EAU A;  4D6D A;  1D6U A;  3QFY A;  3QFZ A;  1UMP A;  3T09 A;  2V8I A;  3N0F A;  4GAX A;  3RSY A;  3UD2 A;  4KFE A;  5CA3 A;  1W6G A;  3NRE A;  3BUQ A;  3E80 A;  1NSM A;  1MN0 A;  3ANK A;  1JYN A;  3EZ8 A;  5IL8 A;  2BBC A;  2XWB B;  2WMF A;  1N7O A;  1H3C A;  1UI8 A;  3BVV A;  3Q7A B;  2CIQ A;  1NSV A;  2CQT A;  1NC5 A;  4D71 A;  5IK9 A;  3T0B A;  2E2T A;  2CFW A;  3HXE B;  3SDV A;  1IVU A;  1HXG A;  1N4Q B;  2GZ6 A;  4L6X A;  1IU7 A;  1NS7 A;  4WVC A;  3P5P A;  3OED A;  1IA7 A;  1RJO A;  5AGD A;  1HZF A;  4TTG A;  1JCS B;  1N1Z A;  3N0G A;  3VW5 A;  3X41 A;  1FP3 A;  4ZG8 A;  2OW6 A;  1DCE B;  1JYX A;  1G9J A;  1O1T B;  4L0G A;  2BRV X;  1AVK A;  2HTB A;  4GTR B;  4V1R A;  1QAK A;  1O6R A;  3C72 B;  4YDO B;  4DUV A;  4OZW A;  2XHN A;  3G6J B;  1GXM A;  1TQS A;  4KTR A;  1QSJ A;  5GY3 A;  3DX2 A;  3DCD A;  1XWT A;  2H6I B;  1RWC A;  2C11 A;  3SDR A;  2Y73 A;  3NBB A;  3DX4 A;  4D6I A;  1JZ8 A;  3PZ4 B;  4JJJ A;  5C05 A;  3EJS A;  2V8J A;  4GTS B;  2FV1 A;  4C1S A;  4EL8 A;  3SX1 A;  2AFA A;  3SQC A;  3BVU A;  2F18 A;  4GTT B;  1SA4 B;  2D73 A;  1F9O A;  1H3A A;  2JG0 A;  5ILI A;  1MZC B;  1F4A A;  1HWW A;  2CFD A;  3SDT A;  2B4F A;  4YDE B;  1EGU A;  4DI5 A;  1PX4 A;  3WA2 X;  2H6F B;  3DST B;  1L1Y A;  4GTO B;  1AYX A;  3PZ3 B;  1SQC A;  2WMI B;  2BT3 A;  2D1W A;  4K3A A;  3OS7 A;  2E2U A;  5ILZ A;  3M7L A;  1N24 A;  2F7R A;  1NXC A;  1TNB B;  3QWT A;  3VD9 A;  1WU4 A;  2V3P A;  1GHQ A;  1NS0 A;  1H12 A;  3NBJ A;  2EAB A;  1FBO A;  1N20 A;  5FOB B;  1QBQ B;  1R34 A;  1OJP A;  4LNB B;  2ONH A;  3TY1 A;  4D94 A;  3SAE A;  2PNC A;  2BB5 A;  4F13 A;  4EV2 A;  1HCU A;  1LTX B;  2I07 B;  3PZ1 B;  4FNP A;  1FT1 B;  2WVY A;  2WW1 A;  2ZIR B;  5FO8 B;  3E30 B;  5KKB A;  1O79 A;  2XN2 A;  2PMV A;  4RNQ A;  3WC3 A;  3W5M A;  1DYU A;  3ANI A;  3KN4 A;  4D6J A;  3N9H A;  1N21 A;  4BZE A;  3DPY B;  1FMI A;  1YGA A;  4UFC A;  1W7C A;  3DEC A;  3WIW A;  4ZH1 A;  3M00 A;  4AYQ A;  1AVL A;  5DGQ A;  1V7X A;  3BUD A;  4FUS A;  1CB8 A;  1N7N A;  1UI7 A;  4MU9 A;  1K72 A;  3EU8 A;  4FXK B;  1TQU A;  2WCO A;  2ZBL A;  3BGA A;  4DUX A;  1JCR B;  2Z07 A;  1LVN A;  2JKP A;  4FNR A;  4ZRP A;  2OQE C;  1F1S A;  4TF4 A;  1HTY A;  2V8K A;  1LOH A;  1C82 A;  2FUT A;  1S63 B;  4D8O A;  3T0A A;  3E6U A;  1GA2 A;  1X1J A;  3PMM A;  1JZ5 A;  3M74 A;  3K11 A;  5DHK A;  1UT9 A;  1WMN A;  1TQT A;  4FNV A;  3KLS A;  3DRA B;  1H39 A;  2BB6 A;  3Q7F B;  4Q2B A;  2CWV A;  3DYP A;  2QNO A;  3MV0 1;  1V5C A;  4OK4 A;  1IQY A;  3E32 B;  2IEJ B;  3J7H A;  3OB8 A;  2JJB A;  2YIK A;  3WIQ A;  3GT5 A;  5JPN B;  3W7U A;  2XSG A;  3G4D A;  1FAE A;  1LXM A;  1TN6 B;  1N22 A;  1K1Y A;  3ACT A;  1H54 A;  2FBA A;  1TNU B;  1JCQ B;  3MV1 1;  1WU5 A;  1LD8 B;  1N4R B;  1X1I A;  1GXO A;  1KRE A;  1TN7 B;  3KSQ B;  3VD4 A;  3CIH A;  2WYN A;  2WMH A;  3BUB A;  3BLC A;  3VDB A;  3RX7 A;  3MPH A;  4FXG B;  1NSS A;  1N95 B;  1W3Y A;  3ANJ A;  3NFV A;  3E37 B;  4D4A A;  1N9E A;  1AGM A;  1SII A;  4D1J A;  1KSI A;  3PYA A;  1TXK A;  3CV5 A;  2DRQ A;  3DSS B;  2ZXQ A;  3S4B A;  3HIG A;  3VDA A;  3IAP A;  1FT2 B;  1W6J A;  3ON6 A;  4D72 A;  1V7W A;  2H6H B;  3X3Z A;  4F10 A;  2ALW A;  5DHI A;  1CEM A;  5IKA A;  2A8Z A;  3T33 A;  1W2Z A;  1UG9 A;  1A2V A;  2WOF A;  2RGK A;  3QT3 A;  1V7V A;  1N7R A;  2DRO A;  3QXQ A;  1L7J A;  5IK0 A;  2EAE A;  1LUR A;  4MMI A;  3EJU A;  3VD5 A;  1N4P B;  1QAZ A;  5FO9 B;  3AFL A;  3ECQ A;  3T0U A;  2SQC A;  2VN7 A;  2BED B;  1IVW A;  3SFY B;  1JRQ A;  1MMY A;  1HM3 A;  2FUZ A;  3Q73 B;  5EAT A;  3A3V A;  4WVB A;  3IAQ A;  2RI8 A;  1JZ2 A;  4XUV A;  1KSC A;  3EJR A;  3GZK A;  4FNQ A;  3E73 A;  1N1B A;  3WUX A;  1CLC A;  2FYV A;  3Q78 B;  1RWH A;  4V1S A;  4D4B A;  1ULV A;  1HV6 A;  1QWU A;  4E1Y A;  3U7V A;  4CJ0 A;  4EV5 A;  3ALA A;  4LIX A;  1H3B A;  3VD7 A;  1N4S B;  2WVX A;  3A0O A;  1X81 B;  5ILD A;  3SXX A;  4LNV A;  3E7J A;  4FJQ A;  4KTP A;  5DGR A;  3SDQ A;  2WDA A;  4WU0 A;  3VSN A;  1OJO A;  1PX3 A;  2JKE A;  2OQE A;  2WW3 A;  3PGB A;  1HXK A;  1KS8 A;  1I8Q A;  5M7I A;  4DOD A;  3X3Y A;  1D6Z A;  1KKT A;  1G87 A;  3QRY A;  1TQV A;  3X3X A;  3T08 A;  1KWF A;  1TNY B;  4Z4L A;  1J0M A;  3D4Y A;  3QR8 A;  2D8L A;  3E34 B;  3REN A;  3KBU C;  4QT9 A;  1DOG A;  1US1 A;  4CE7 A;  3AMO A;  3I3E A;  3M78 A;  1IS9 A;  3WKH A;  1EKM A;  1YQ2 A;  1F4H A;  3MUZ 1;  4AQ0 A;  3F59 A;  3UD1 A;  3CZJ A;  3VDC A;  3E33 B;  4EHM B;  3EJP A;  3GLY A;  1RWG A;  5ILH A;  3D3I A;  3QG0 A;  2RDY A;  1PU4 A;  1H13 A;  3PZ2 B;  3MUY 1;  4MMH A;  1O1S B;  3S9V A;  2WMK A;  1HM2 A;  3IMH A;  1K1X A;  3KBT C;  2ONG A;  3QDE A;  5JMF A;  5ILK A;  1SIH A;  2AHF A;  3P2C A;  2CIR A;  2CWU A;  1HMW A;  1QX1 A;  2WMG A;  1N23 A;  2E2V A;  3P5R A;  2E24 A;  1DP0 A;  1TNZ B;  1O6H A;  1X1H A;  3WKF A;  4YCR A;  4RNL A;  4Q88 A;  1RQ5 A;  3S4C A;  3QSP A;  4MBG B;  2KXS A;  1HN1 A;  3BS6 A;  3M02 A;  2V3N A;  1H35 A;  4NEI A;  4OZV A;  5IKH A;  4D6F A;  1NKG A;  5FO7 B;  3VSM A;  2F1B A;  1Z45 A;  3H7L A;  3I3B A;  3Q79 B;  1N9A B;  4DLO A;  2FUQ A;  3S4A A;  3AFJ A;  4ZRQ A;  1GAI A;  2CFG A;  3BUI A;  2WO0 A;  1HXC A;  3H3K A;  1TNO B;  2OOV C;  2KXR A;  1O5M B;  4D1I A;  2YFN A;  3M72 A;  4KKJ A;  1WU6 A;  3M76 A;  5GW7 A;  3D52 A;  2JKA A;  2CWT A;  5ILJ A;  1QQF A;  2WYI A;  1H14 A;  4DLQ A;  3DSW B;  2WZS A;  1D6Y A;  2F0Y B;  4K35 A;  1HX9 A;  2CG0 A;  1X9D A;  1TF4 A;  1KSD A;  1G9G A;  4WVA A;  2ZZR A; 
#chains in the Genus database with same CATH homology
 3T2Q A;  3T2P A;  1F4A A;  1MMY A;  3NNB A;  4BZF A;  4D6C A;  1HM3 A;  3NJV A;  1EGU A;  2WMI A;  1PX4 A;  3IAQ A;  1JZ2 A;  1JZ6 A;  1HN0 A;  2BRP A;  3SEP A;  1J0N A;  2WMI B;  4OJZ A;  3OS7 A;  1OJN A;  4D6G A;  1N7Q A;  1F9G A;  1K1W A;  1NSX A;  3VD9 A;  1RWH A;  2E22 A;  1NS0 A;  1ULV A;  1HV6 A;  3T0D A;  2WMJ A;  4E1Y A;  1OJP A;  3TY1 A;  1NSR A;  1LXK A;  1L7K A;  3VD7 A;  4F13 A;  2WVX A;  3A0O A;  1NS8 A;  1SO0 A;  2ZQ0 A;  4BZH A;  4D6H A;  2WVX B;  3E7J A;  2X03 A;  1HMU A;  5JMD A;  2WDA A;  2Q1F A;  3Q1N A;  3VSN A;  2WVY A;  1OJO A;  2WW1 A;  1PX3 A;  2JKE A;  1MMU A;  1JZ3 A;  4D6E A;  2WW3 A;  1MMX A;  2BRW A;  1NS2 A;  1I8Q A;  1N7P A;  3WVF A;  1JYW A;  4D6J A;  1LF9 A;  3T08 A;  1JOV A;  1J0M A;  4BZE A;  1NS4 A;  1MMZ A;  3I3E A;  1RWF A;  1YGA A;  3A24 A;  3K25 A;  3DEC A;  3VD3 A;  3MUZ 1;  1YQ2 A;  1F4H A;  3WFA A;  4AQ0 A;  1RW9 A;  4D6D A;  3CZJ A;  1CB8 A;  1N7N A;  3MWX A;  3VDC A;  3T09 A;  2WCO A;  1RWG A;  3BGA A;  4DUX A;  2CIS A;  4OK2 A;  2JKP A;  2HTA A;  3OBA A;  4J5T A;  3MUY 1;  4MMH A;  2WMK A;  3IMH A;  1HM2 A;  3NRE A;  3E80 A;  1K1X A;  1F1S A;  1NSM A;  1MN0 A;  1SNZ A;  1LF6 A;  1LOH A;  1JYN A;  1C82 A;  2FUT A;  2D73 A;  3T0A A;  2WMF A;  1X1J A;  1N7O A;  1JZ5 A;  1JZ4 A;  5JMF A;  1NSZ A;  2CIQ A;  1NSV A;  4FNV A;  4D71 A;  1JYV A;  3T0B A;  1RWA A;  2CIR A;  3E1F 1;  3DYP A;  3MV0 1;  4OK4 A;  1NS7 A;  3J7H A;  4DUW A;  2WVZ A;  3OB8 A;  1HMW A;  2WMG A;  2WW2 A;  2XSG A;  1LXM A;  2E24 A;  1K1Y A;  4TTG A;  1DP0 A;  1X1H A;  3MV1 1;  1X1I A;  4RNL A;  3DYM A;  5A1A A;  1HN1 A;  3NJX A;  3VD4 A;  2WMH A;  3BS6 A;  3BLC A;  4NEI A;  4OZV A;  4D6F A;  1JYX A;  1NKG A;  3DYO A;  3VDB A;  1NSS A;  3VSM A;  1Z45 A;  1W3Y A;  3NFV A;  2BRV X;  3I3B A;  2HTB A;  3T2O A;  2FUQ A;  1TXK A;  4DUV A;  2ZXQ A;  4OZW A;  2XHN A;  3VDA A;  4BZG A;  1JZ7 A;  3IAP A;  4D72 A;  4F10 A;  3I3D A;  3DCD A;  1RWC A;  2JKA A;  4D6I A;  1UG9 A;  1JZ8 A;  1N7R A;  1L7J A;  1OJM A;  2WZS A;  5E1Q A;  1LUR A;  1NSU A;  4MMI A;  3VD5 A;  1QAZ A;  3AFL A;  3ECQ A;  2WW0 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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