2BRWA

Crystal structure of streptococcus pneumoniae hyaluronate lyase from 30percent pegmme.
Total Genus 247
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
247
sequence length
721
structure length
721
Chain Sequence
VKDTYTDRLDDWNGIIAGNQYYDSKNDQMAKLNQELEGKVADSLSSISSQADRIYLWEKFSNYKTSANLTATYRKLEEMAKQVTNPSSRYYQDETVVRTVRDSMEWMHKHVYNSEKSIVGNWWDYEIGTPRAINNTLSLMKEYFSDEEIKKYTDVIEKFVPDPEHFRKTTDNPFKALGGNLVDMGRVKVIAGLLRKDDQEISSTIRSIEQVFKLVDQGEGFYQDGSYIDHTNVAYTGAYGNVLIDGLSQLLPVIQKTKNPIDKDKMQTMYHWIDKSFAPLLVNGELMDMSRGRSISRANSEGHVAAVEVLRGIHRIADMSEGETKQRLQSLVKTIVQSDSYYDVFKNLKTYKDISLMQSLLSDAGVASVPRTSYLSAFNKMDKTAMYNAEKGFGFGLSLFSSRTLNYEHMNKENKRGWYTSDGMFYLYNGDLSHYSDGYWPTVNPYKMPGTTETDAKRADSDTGKVLPSAFVGTSKLDDANATATMDFTNWNQTLTAHKSWFMLKDKIAFLGSNIQNTSTDTAATTIDQRKLESSNPYKVYVNDKEASLTEQEKDYPETQSVFLESSDSKKNIGYFFFKKSSISMSKALQKGAWKDINEGQSDKEVENEFLTISQAHKQNGDSYGYMLIPNVDRATFNQMIKELESSLIENNETLQSVYDAKQGVWGIVKYDDSVSTISNQFQVLKRGVYTIRKEGDEYKIAYYNPETQESAPDQEVFKKL
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Alternate Structural Conformations of Streptococcus Pneumoniae Hyaluronan Lyase: Insights Into Enzyme Flexibility and Underlying Molecular Mechanism of Action.
pubmed doi rcsb
source organism Streptococcus pneumoniae
molecule tags Lyase
molecule keywords HYALURONATE LYASE
total genus 247
structure length 721
sequence length 721
chains with identical sequence B
ec nomenclature ec 4.2.2.1: Hyaluronate lyase.
pdb deposition date 2005-05-11

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02278 Lyase_8 Polysaccharide lyase family 8, super-sandwich domain
A PF02884 Lyase_8_C Polysaccharide lyase family 8, C-terminal beta-sandwich domain
A PF08124 Lyase_8_N Polysaccharide lyase family 8, N terminal alpha-helical domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.50.10.100 Mainly Alpha Alpha/alpha barrel Glycosyltransferase Chondroitin AC/alginate lyase 2brwA01
2.60.220.10 Mainly Beta Sandwich Chondroitinase Ac; Chain A, domain 3 Polysaccharide lyase family 8-like, C-terminal 2brwA03
2.70.98.10 Mainly Beta Distorted Sandwich Beta-galactosidase; Chain A, domain 5 Beta-galactosidase; Chain A, domain 5 2brwA02
3IAPA 1N7OA 1LF9A 3A0OA 3VSMA 1YGAA 1CB8A 1J0NA 1ULVA 2HTBA 4D6HA 3VD3A 3E80A 1OJNA 3T2QA 2FUQA 1HM3A 1RW9A 3OBAA 3VDBA 2WVYA 1HN0A 3J7HA 1K1YA 1JOVA 2E24A 2WDAA 2ZXQA 1L7KA 2JKAA 3DYMA 1NSRA 1RWFA 2CIRA 3NFVA 1OJOA 2WW0A 3NREA 1JZ3A 4F10A 1SNZA 1F1SA 1HMWA 2WVZA 1NS8A 1MMUA 1LXMA 4E1YA 3VDCA 4NEIA 2WCOA 4D6JA 1NSMA 1OJMA 4BZHA 4F13A 2CISA 2WW2A 1NS0A 1TXKA 1PX4A 3T09A 1LURA 1JZ7A 3OS7A 2WVXA 1JZ2A 4OZVA 2WMFA 5JMFA 3BGAA 4DUXA 1NSVA 1LXKA 3E7JA 3OB8A 3T08A 3VD4A 4OK2A 4MMHA 2WVXB 3VDAA 1F9GA 1LOHA 1MMYA 2ZQ0A 1NSUA 1JYWA 4OZWA 3T0AA 5E1QA 2WMHA 3NJXA 1MN0A 1L7JA 3WFAA 1JYNA 1MMZA 3DYPA 5JMDA 1JZ8A 1N7NA 1I8QA 4BZGA 1YQ2A 4D6DA 2WZSA 1X1HA 1DP0A 4D6GA 3MV11 1HV6A 2CIQA 1RWCA 1RWHA 1F4AA 1K1XA 1HM2A 4OJZA 2X03A 1NS4A 2WMIB 2BRPA 2E22A 1JYVA 1N7RA 2WMGA 1NSZA 1RWGA 1HN1A 3MWXA 3E1F1 4DUVA 2XHNA 3AFLA 3T2OA 4D6FA 1UG9A 1HMUA 1C82A 1SO0A 4DUWA 2WW1A 2JKEA 3VD9A 1NS7A 3A24A 1QAZA 2Q1FA 1Z45A 2WMKA 1X1JA 3T2PA 4BZEA 2WMJA 3I3BA 3I3EA 1F4HA 4BZFA 3NNBA 2JKPA 3Q1NA 1N7QA 2XSGA 2WW3A 3VSNA 3SEPA 4D71A 3DYOA 1LF6A 2BRVX 4FNVA 4MMIA 3DECA 1JZ5A 1NSXA 3K25A 1NKGA 4AQ0A 3MUZ1 1JZ6A 1NS2A 3CZJA 4D6CA 4D6EA 3VD7A 1OJPA 3MV01 3T0DA 3NJVA 1NSSA 3VD5A 2HTAA 2D73A 4OK4A 2WMIA 5A1AA 1JZ4A 4RNLA 2BRWA 1N7PA 3T0BA 1K1WA 3IAQA 1J0MA 3I3DA 4TTGA 1PX3A 1MMXA 3IMHA 4D72A 3DCDA 1X1IA 3MUY1 4D6IA 3ECQA 2FUTA 1RWAA 1JYXA 1W3YA 1EGUA
chains in the Genus database with same CATH superfamily
1N7OA 1LF9A 2XWBB 4GL3A 3VSMA 4D1JA 2HTBA 1ULVA 1AYXA 1QQFA 1X9DA 3SXXA 3QT9A 3CZSA 3BLCA 5ILJA 1HM3A 1R33A 4M76A 3M76A 2WVYA 3J7HA 1K1YA 3P2CA 4QT9A 3S4CA 1JS4A 2YFOA 3SDVA 5IKAA 3DYMA 1SA4B 2A8ZA 2WIIB 3LVTA 3NFVA 1HX9A 3M7CA 4EL8A 1A2VA 4MU9A 5DHIA 3OXUA 1IVVA 5DHKA 3P5RA 1F1SA 4CJ1A 1HMWA 2CFLA 2F7PA 1FPPB 3P5PA 1MMUA 3DX3A 1LXMA 3KBUC 2OQEA 4ZRPA 3S4DA 2DRRA 3QFZA 4NEIA 4D6JA 1NSMA 1TNYB 1CLCA 4AYRA 4BZHA 4F13A 2BEDB 1FBOA 3SQCA 1NS0A 3K11A 1HXCA 1TNBB 1G9GA 3DX1A 3PGBA 1JZ7A 2WVXA 3W5MA 3OEDA 5JMFA 4DUXA 3TY1A 5ILHA 1GA2A 4MMHA 5IL3A 3KSQB 1MMYA 2ZQ0A 1XWTA 2CG1A 1JYWA 1UI7A 1IVXA 2FUZA 3SDQA 5E1QA 1TQTA 4ZH5A 3BS6A 3WFAA 3M74A 4DLQA 3E37B 2XN1A 2V8JA 3BUIA 4BOJA 1H3CA 1AVKA 2WZSA 2IEJB 4FNQA 3MV11 1RWCA 3HIGA 4D1IA 2ZISB 4OJZA 3QSPA 1V5CA 2CFGA 5ILIA 2BRPA 1NSZA 3WKHA 2PN5A 2WY7A 3X40A 3UD1A 1IQYA 3E1F1 3RENA 3AFLA 2V3PA 2E2TA 4Q88A 4D6FA 4WVBA 1N23A 4DUWA 2ZL8A 3BVUA 3Q7FB 3D5RA 2Q1FA 3QPFA 1X1JA 1SIIA 4BZEA 1OACA 2BB5A 3I3EA 3DSWB 4FNTA 1FP3A 2EADA 4BZFA 1N9EA 1N7QA 1R76A 3D52A 1TNUB 4WVCA 1IQXA 2WW3A 5IL8A 4ZRQA 1LF6A 4D71A 1SQCA 4GTPB 2G02A 3M02A 1GXMA 1WZZA 2NVPA 5FOBB 2DROA 3SFXB 1L2AA 1JZ5A 3QFYA 3KIIA 3DSUB 2ZIRB 3K25A 3M7BA 3T0UA 1GXNA 4TXTA 1HXKA 3N9HA 3DX4A 3E33B 3T0DA 3M7LA 1NSSA 3SDTA 3HXDB 2VN4A 2F7RA 3CZNA 4WVAA 3QR8A 3QXQA 1K72A 4FNSA 3SX1A 1H3AA 5GW7A 3T0BA 1G87A 3DSVB 1FO3A 1AGMA 1O5MB 1JRQA 3PZ1B 1LTXB 4D6IA 1H13A 2FUTA 1N95B 1WMPA 1QSJA 3QDEA 2WW2A 3BVTA 3ECQA 1SA5B 1GSZA 1X81B 1QAFA 2R2LB 5MEHA 3SDRA 1WU6A 4FXGB 1WMOA 1OJNA 3T2QA 1FT1B 1KSDA 2GZ6A 1RW9A 1SPUA 1W7CA 1HXGA 2F7QA 3PZ3B 3MPHA 5DGQA 2WDAA 2ZXQA 1L7KA 4K3AA 1HXAA 5EATA 1QWNA 2JKAA 1D6UA 5KBPA 2WW0A 1FBWA 1O1RB 4F10A 4ZG8A 2V8IA 1W2ZA 2WO0A 1N94B 3WIWA 4EV5A 1QALA 2WYNA 4DOEA 2YX9A 4BTXA 3M7EA 1OJMA 5FO9B 3Q79B 2SQCA 2EAEA 4EV2A 2EABA 5IKHA 4LIXA 1W5ZA 3RJ3A 3T09A 1NXCA 1V7XA 3RRSA 1GAIA 3EQAA 1KZOB 5JPMB 2H6GB 3ANIA 4KTRA 1N20A 5ILZA 1NSVA 1LXKA 3E7JA 3PQIA 3EJRA 3T08A 1HCUA 4GTTB 2B39A 1H12A 3DSTB 3A3VA 3BVVA 3K7XA 4OZWA 5EAUA 3T0AA 3VXDA 1WU4A 3EU5B 5KKBA 2XN0A 1QBQB 1MMZA 4BTWA 5M7YA 3AMOA 5JMDA 1O7DD 1N7NA 4FNUA 5FO7B 1YQ2A 2F1AA 4D6GA 2PMVA 3WKIA 3EUVB 4FJQA 2FBAA 3W7UA 1F4AA 1RWHA 4FXKB 1K1XA 2X03A 2WMIB 3ANKA 1KREA 1DOGA 2WY8A 1GAHA 2E22A 4Z4LA 1UMPA 3BVXA 1RWGA 2XN2A 2JJBA 1AVLA 3Q7AB 1LD8B 2QNOA 2JF4A 2XHNA 3DSXB 2OOVC 4LNBB 3BVWA 2G0DA 2F0YB 4YDOB 1XW2A 3HXFB 1C82A 3QXFA 2WGQA 2WW1A 2JKEA 1NS7A 4D4CA 1HZFA 3KLSA 4Z4JA 3M77A 2CWVA 2WMJA 1LVNA 3Q75B 1N4RB 3NNBA 2JKPA 1GHQA 1W6KA 4L6XA 1WMNA 2EACA 2J5CA 1HTYA 3VSNA 3WIRA 3EJUA 3DYOA 3LOYA 3DDFA 1TQUA 1N22A 4FNVA 2FYVA 1D8DB 1QX1A 4KTPA 3DPYB 3EJSA 4K35A 3HXEB 1F9OA 5IK0A 4AQ0A 1NS2A 3ANJA 2VN7A 3PMMA 5IK6A 3D50A 4D6CA 2AFAA 3E73A 1QAKA 1GXOA 2KXSA 3NBJA 3RX5A 3N0GA 2RGKA 3QG0A 1RQ5A 1UI8A 1JZ4A 4XUVA 2BRWA 1SIHA 1K1WA 1J0MA 1RKYA 4D94A 1H14A 1MMXA 3EJQA 3IMHA 3DRAB 1TN8B 1N9AB 1RWAA 4JJJA 2C11A 3IAPA 2D8LA 3A0OA 4DLOA 1CB8A 1H39A 2V8KA 1C3DA 3D3IA 2FUQA 2OKXA 2Y73A 3WA3A 3OBAA 1O1TB 3PYAA 1EKMA 1IS9A 1G9JA 2H6IB 1DL2A 1N4PB 2E24A 5AGDA 3D4YA 1NSRA 1N1ZA 3K5TA 2F18A 2WVZA 1D6ZA 3WKFA 1NS8A 3PYBA 4E1YA 1O79A 2V3NA 3VDCA 2CFDA 2OW7A 1S63B 3ACTA 2CISA 1TXKA 2OW6A 3SFYB 3OS7A 1H35A 3M01A 4D8OA 1JZ2A 4OZVA 2CQTA 2WMFA 3BGAA 4LNVA 1IVUA 3ALAA 4BTYA 4Q2BA 4D4AA 3WC3A 3VDAA 1LOHA 3F59A 2RI9A 3DX2A 2GOXA 2WMHA 3NJXA 1MN0A 1L7JA 1JYNA 1N4SB 4L9PB 3AFJA 2CFWA 1I8QA 4FNRA 3RX8A 3H7LA 1H37A 4KKJA 4DODA 1FT2B 3W7TA 1X1HA 4BZGA 2FV1A 1S64B 2ZBLA 2CIQA 2D1WA 4GTOB 4LNGB 1FAEA 1NC5A 3PZ2B 5M7IA 5CZLA 2H6FB 2KXRA 1NI1B 3KBTC 1IVWA 1JYVA 1N7RA 2WMGA 1HN1A 3MWXA 2WYHA 3WVFA 4KFFA 3T2OA 3M73A 2DRSA 3MI6A 1O6HA 3SDUA 3HXBB 3E6UA 1FCEA 3WKGA 4GTMB 1SO0A 3H2WA 3EU8A 3E32B 2A73B 5C05A 2GH4A 4GTQB 3A24A 3BLBA 1N24A 3VW5A 1Z45A 3T2PA 3S9VA 3HIIA 4GTVB 4J5TA 3D51A 3I3BA 1F4HA 3EZ8A 3GLYA 3M71A 3Q1NA 1KWFA 1V5DA 3M75A 3BUDA 3DECA 4MMIA 4YCRA 3S4BA 4AYQA 3QWTA 3QRYA 1NSXA 1O6RA 4MBGB 5ILYA 5IK9A 1JZ6A 3G4DA 3CZJA 2ONHA 1D6YA 1TQSA 4AYPA 1D8EB 2JG0A 5JPNB 3VD5A 1TQWA 2D73A 2AHGA 4OK4A 2BBCA 1W6JA 3WUXA 3C72B 2Z07A 4BOKA 2F1BA 1KFGA 1N7PA 3DX0A 3GT5A 3IAQA 5GY3A 1FMIA 3S4AA 4D72A 1JZ3A 2F6DA 4C1SA 5DGRA 2CG0A 3Q78B 3AMOB 2XQWA 3Q73B 3MUY1 3ACSA 2WOFA 3LZ9A 1EGUA 1JYXA 3EJPA 1YGAA 2OOVA 1TNOB 1IU7A 1J0NA 1F9DA 1G6IA 4GAXA 3DDGA 3NBBA 4V1SA 4D6HA 1JCRB 3VD3A 3E80A 4CJ0A 1O1SB 3ON6A 3W5NA 1IA6A 3VDBA 1O6QA 1HN0A 3KSLB 1CEMA 1FO2A 1JOVA 5IM1A 1LD7B 3HI7A 2NOJA 1TU5A 1GLMA 1PU4A 1RWFA 1XWQA 2CIRA 3CU7A 1MZCB 1OJOA 2CWTA 3NREA 2ALWA 2OQEC 1SNZA 2RI8A 1PS3A 3TF4A 2WOHA 5ILKA 3G6JB 2WCOA 3D5SA 5EASA 5CA3A 1WU5A 2H6HB 3GZKA 3KN4A 1KKTA 4WU0A 1TNZB 1KS8A 1AV4A 3EJTA 3KQ4A 5GZKA 2AHFA 1LURA 3M72A 1PX4A 4KFEA 3X3XA 2BT3A 1VD5A 4FUSA 4KFDA 1UT9A 1H3BA 3OB8A 4FNPA 1HWWA 3VD4A 4OK2A 4AYOA 2WVXB 1V7WA 2DRQA 3M00A 1F9GA 1N4QB 1TF4A 1H54A 1NSUA 2WINB 1N21A 1W4NA 2FV0A 3E30B 1N1BA 1TQVA 4TF4A 3DYPA 1KSCA 4UFCA 1JZ8A 3RSYA 1DCEB 4D6DA 2CQSA 3CIHA 1DP0A 4V1RA 1DYUA 1RJOA 2YFNA 1HV6A 4YDEB 2B4FA 3W7WA 3WIQA 3N0FA 3X17A 3W7XA 1HM2A 4KKIA 2W0QA 2XWJB 1NS4A 1H36A 4CE7A 5E2JA 1W6GA 3W7SA 1JCSB 3D4ZA 2ZZRA 3BUQA 2CWUA 3QT3A 3E34B 4DUVA 2WYIA 2E2UA 1UG9A 1HMUA 2XFGA 3VD9A 2ONGA 2CFKA 2C10A 3X3YA 1QAZA 3X3ZA 1TN7B 3DSSB 1NL4B 2WMKA 3SAEA 3T33A 1US1A 3HXCB 3X42A 4EHMB 2XSGA 3CV5A 3SEPA 3X41A 3M78A 2BRVX 4L0GA 4RNQA 2P0VA 5CD2A 3RX7A 3U7VA 1R34A 1KZPB 1NKGA 3MUZ1 3UD2A 2F7OA 4D6EA 2D5JA 1OJPA 3MV01 3VD7A 3NJVA 2RDYA 3PZ4B 5FO8B 2HTAA 2WMIA 3WA2X 4ZH1A 5A1AA 3BUBA 2I07B 1V7VA 3BUPA 4D4BA 1L1YA 4D4DA 1QWUA 1KRFA 1KSIA 2E2VA 4RNLA 1TN6B 3G4FA 4DI5A 3I3DA 4TTGA 4ONTA 1IA7A 1JCQB 2BB6A 5ILDA 1PX3A 2PNCA 4GTRB 3DCDA 1X1IA 4GTSB 2Y74A 2YIKA 1W6CA 1W3YA 3H3KA
chains in the Genus database with same CATH topology
3IAPA 1N7OA 1LF9A 3A0OA 3VSMA 1YGAA 1CB8A 1J0NA 1ULVA 2HTBA 4D6HA 3VD3A 3E80A 1OJNA 3T2QA 2FUQA 3BLCA 1HM3A 1RW9A 3OBAA 3VDBA 2WVYA 1HN0A 3J7HA 1K1YA 1JOVA 2E24A 2WDAA 2ZXQA 1L7KA 2JKAA 3DYMA 1NSRA 1RWFA 2CIRA 3NFVA 1OJOA 2WW0A 3NREA 1JZ3A 4F10A 1SNZA 1F1SA 1HMWA 2WVZA 1NS8A 1MMUA 1LXMA 4E1YA 3VDCA 4NEIA 2WCOA 4D6JA 1NSMA 1OJMA 4BZHA 4F13A 2CISA 2WW2A 1NS0A 1TXKA 1PX4A 3T09A 1LURA 1JZ7A 3OS7A 2WVXA 1JZ2A 4OZVA 2WMFA 5JMFA 3BGAA 4DUXA 3TY1A 1NSVA 1LXKA 3E7JA 3OB8A 3T08A 3VD4A 4OK2A 4MMHA 2WVXB 3VDAA 1F9GA 1LOHA 1MMYA 2ZQ0A 1NSUA 1JYWA 4OZWA 3T0AA 5E1QA 2WMHA 3BS6A 1MN0A 1L7JA 3NJXA 3WFAA 1MMZA 3DYPA 1JYNA 5JMDA 1JZ8A 1N7NA 1I8QA 4BZGA 1YQ2A 4D6DA 2WZSA 1X1HA 1DP0A 4D6GA 3MV11 1HV6A 2CIQA 1RWCA 1RWHA 1F4AA 1K1XA 1HM2A 4OJZA 2X03A 1NS4A 2WMIB 2BRPA 2E22A 1JYVA 1N7RA 2WMGA 1NSZA 1RWGA 1HN1A 3MWXA 3WVFA 3E1F1 4DUVA 2XHNA 3AFLA 3T2OA 4D6FA 1UG9A 1HMUA 1C82A 1SO0A 4DUWA 2WW1A 2JKEA 3VD9A 1NS7A 3A24A 1QAZA 2Q1FA 1Z45A 2WMKA 1X1JA 3T2PA 4BZEA 2WMJA 3I3BA 4J5TA 3I3EA 1F4HA 4BZFA 3NNBA 2JKPA 3Q1NA 1N7QA 2XSGA 2WW3A 3VSNA 3SEPA 4D71A 3DYOA 1LF6A 2BRVX 4FNVA 4MMIA 3DECA 1JZ5A 1NSXA 3K25A 1NKGA 4AQ0A 3MUZ1 1JZ6A 1NS2A 3CZJA 4D6CA 4D6EA 3VD7A 1OJPA 3MV01 3T0DA 3NJVA 1NSSA 3VD5A 2HTAA 2D73A 4OK4A 2WMIA 5A1AA 1JZ4A 4RNLA 2BRWA 1N7PA 3T0BA 1K1WA 3IAQA 1J0MA 3I3DA 4TTGA 1PX3A 1MMXA 3IMHA 4D72A 3DCDA 1X1IA 3MUY1 4D6IA 3ECQA 2FUTA 1RWAA 1JYXA 1W3YA 1EGUA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3IAP A;  1N7O A;  1LF9 A;  3A0O A;  3VSM A;  1YGA A;  1CB8 A;  1J0N A;  1ULV A;  2HTB A;  4D6H A;  3VD3 A;  3E80 A;  1OJN A;  3T2Q A;  2FUQ A;  1HM3 A;  1RW9 A;  3OBA A;  3VDB A;  2WVY A;  1HN0 A;  3J7H A;  1K1Y A;  1JOV A;  2E24 A;  2WDA A;  2ZXQ A;  1L7K A;  2JKA A;  3DYM A;  1NSR A;  1RWF A;  2CIR A;  3NFV A;  1OJO A;  2WW0 A;  3NRE A;  1JZ3 A;  4F10 A;  1SNZ A;  1F1S A;  1HMW A;  2WVZ A;  1NS8 A;  1MMU A;  1LXM A;  4E1Y A;  3VDC A;  4NEI A;  2WCO A;  4D6J A;  1NSM A;  1OJM A;  4BZH A;  4F13 A;  2CIS A;  2WW2 A;  1NS0 A;  1TXK A;  1PX4 A;  3T09 A;  1LUR A;  1JZ7 A;  3OS7 A;  2WVX A;  1JZ2 A;  4OZV A;  2WMF A;  5JMF A;  3BGA A;  4DUX A;  1NSV A;  1LXK A;  3E7J A;  3OB8 A;  3T08 A;  3VD4 A;  4OK2 A;  4MMH A;  2WVX B;  3VDA A;  1F9G A;  1LOH A;  1MMY A;  2ZQ0 A;  1NSU A;  1JYW A;  4OZW A;  3T0A A;  5E1Q A;  2WMH A;  3NJX A;  1MN0 A;  1L7J A;  3WFA A;  1JYN A;  1MMZ A;  3DYP A;  5JMD A;  1JZ8 A;  1N7N A;  1I8Q A;  4BZG A;  1YQ2 A;  4D6D A;  2WZS A;  1X1H A;  1DP0 A;  4D6G A;  3MV1 1;  1HV6 A;  2CIQ A;  1RWC A;  1RWH A;  1F4A A;  1K1X A;  1HM2 A;  4OJZ A;  2X03 A;  1NS4 A;  2WMI B;  2BRP A;  2E22 A;  1JYV A;  1N7R A;  2WMG A;  1NSZ A;  1RWG A;  1HN1 A;  3MWX A;  3E1F 1;  4DUV A;  2XHN A;  3AFL A;  3T2O A;  4D6F A;  1UG9 A;  1HMU A;  1C82 A;  1SO0 A;  4DUW A;  2WW1 A;  2JKE A;  3VD9 A;  1NS7 A;  3A24 A;  1QAZ A;  2Q1F A;  1Z45 A;  2WMK A;  1X1J A;  3T2P A;  4BZE A;  2WMJ A;  3I3B A;  3I3E A;  1F4H A;  4BZF A;  3NNB A;  2JKP A;  3Q1N A;  1N7Q A;  2XSG A;  2WW3 A;  3VSN A;  3SEP A;  4D71 A;  3DYO A;  1LF6 A;  2BRV X;  4FNV A;  4MMI A;  3DEC A;  1JZ5 A;  1NSX A;  3K25 A;  1NKG A;  4AQ0 A;  3MUZ 1;  1JZ6 A;  1NS2 A;  3CZJ A;  4D6C A;  4D6E A;  3VD7 A;  1OJP A;  3MV0 1;  3T0D A;  3NJV A;  1NSS A;  3VD5 A;  2HTA A;  2D73 A;  4OK4 A;  2WMI A;  5A1A A;  1JZ4 A;  4RNL A;  2BRW A;  1N7P A;  3T0B A;  1K1W A;  3IAQ A;  1J0M A;  3I3D A;  4TTG A;  1PX3 A;  1MMX A;  3IMH A;  4D72 A;  3DCD A;  1X1I A;  3MUY 1;  4D6I A;  3ECQ A;  2FUT A;  1RWA A;  1JYX A;  1W3Y A;  1EGU A; 
#chains in the Genus database with same CATH topology
 1N7O A;  1LF9 A;  2XWB B;  4GL3 A;  3VSM A;  4D1J A;  2HTB A;  1ULV A;  1AYX A;  1QQF A;  1X9D A;  3SXX A;  3QT9 A;  3CZS A;  3BLC A;  5ILJ A;  1HM3 A;  1R33 A;  4M76 A;  3M76 A;  2WVY A;  3J7H A;  1K1Y A;  3P2C A;  4QT9 A;  3S4C A;  1JS4 A;  2YFO A;  3SDV A;  5IKA A;  3DYM A;  1SA4 B;  2A8Z A;  2WII B;  3LVT A;  3NFV A;  1HX9 A;  3M7C A;  4EL8 A;  1A2V A;  4MU9 A;  5DHI A;  3OXU A;  1IVV A;  5DHK A;  3P5R A;  1F1S A;  4CJ1 A;  1HMW A;  2CFL A;  2F7P A;  1FPP B;  3P5P A;  1MMU A;  3DX3 A;  1LXM A;  3KBU C;  2OQE A;  4ZRP A;  3S4D A;  2DRR A;  3QFZ A;  4NEI A;  4D6J A;  1NSM A;  1TNY B;  1CLC A;  4AYR A;  4BZH A;  4F13 A;  2BED B;  1FBO A;  3SQC A;  1NS0 A;  3K11 A;  1HXC A;  1TNB B;  1G9G A;  3DX1 A;  3PGB A;  1JZ7 A;  2WVX A;  3W5M A;  3OED A;  5JMF A;  4DUX A;  3TY1 A;  5ILH A;  1GA2 A;  4MMH A;  5IL3 A;  3KSQ B;  1MMY A;  2ZQ0 A;  1XWT A;  2CG1 A;  1JYW A;  1UI7 A;  1IVX A;  2FUZ A;  3SDQ A;  5E1Q A;  1TQT A;  4ZH5 A;  3BS6 A;  3WFA A;  3M74 A;  4DLQ A;  3E37 B;  2XN1 A;  2V8J A;  3BUI A;  4BOJ A;  1H3C A;  1AVK A;  2WZS A;  2IEJ B;  4FNQ A;  3MV1 1;  1RWC A;  3HIG A;  4D1I A;  2ZIS B;  4OJZ A;  3QSP A;  1V5C A;  2CFG A;  5ILI A;  2BRP A;  1NSZ A;  3WKH A;  2PN5 A;  2WY7 A;  3X40 A;  3UD1 A;  1IQY A;  3E1F 1;  3REN A;  3AFL A;  2V3P A;  2E2T A;  4Q88 A;  4D6F A;  4WVB A;  1N23 A;  4DUW A;  2ZL8 A;  3BVU A;  3Q7F B;  3D5R A;  2Q1F A;  3QPF A;  1X1J A;  1SII A;  4BZE A;  1OAC A;  2BB5 A;  3I3E A;  3DSW B;  4FNT A;  1FP3 A;  2EAD A;  4BZF A;  1N9E A;  1N7Q A;  1R76 A;  3D52 A;  1TNU B;  4WVC A;  1IQX A;  2WW3 A;  5IL8 A;  4ZRQ A;  1LF6 A;  4D71 A;  1SQC A;  4GTP B;  2G02 A;  3M02 A;  1GXM A;  1WZZ A;  2NVP A;  5FOB B;  2DRO A;  3SFX B;  1L2A A;  1JZ5 A;  3QFY A;  3KII A;  3DSU B;  2ZIR B;  3K25 A;  3M7B A;  3T0U A;  1GXN A;  4TXT A;  1HXK A;  3N9H A;  3DX4 A;  3E33 B;  3T0D A;  3M7L A;  1NSS A;  3SDT A;  3HXD B;  2VN4 A;  2F7R A;  3CZN A;  4WVA A;  3QR8 A;  3QXQ A;  1K72 A;  4FNS A;  3SX1 A;  1H3A A;  5GW7 A;  3T0B A;  1G87 A;  3DSV B;  1FO3 A;  1AGM A;  1O5M B;  1JRQ A;  3PZ1 B;  1LTX B;  4D6I A;  1H13 A;  2FUT A;  1N95 B;  1WMP A;  1QSJ A;  3QDE A;  2WW2 A;  3BVT A;  3ECQ A;  1SA5 B;  1GSZ A;  1X81 B;  1QAF A;  2R2L B;  5MEH A;  3SDR A;  1WU6 A;  4FXG B;  1WMO A;  1OJN A;  3T2Q A;  1FT1 B;  1KSD A;  2GZ6 A;  1RW9 A;  1SPU A;  1W7C A;  1HXG A;  2F7Q A;  3PZ3 B;  3MPH A;  5DGQ A;  2WDA A;  2ZXQ A;  1L7K A;  4K3A A;  1HXA A;  5EAT A;  1QWN A;  2JKA A;  1D6U A;  5KBP A;  2WW0 A;  1FBW A;  1O1R B;  4F10 A;  4ZG8 A;  2V8I A;  1W2Z A;  2WO0 A;  1N94 B;  3WIW A;  4EV5 A;  1QAL A;  2WYN A;  4DOE A;  2YX9 A;  4BTX A;  3M7E A;  1OJM A;  5FO9 B;  3Q79 B;  2SQC A;  2EAE A;  4EV2 A;  2EAB A;  5IKH A;  4LIX A;  1W5Z A;  3RJ3 A;  3T09 A;  1NXC A;  1V7X A;  3RRS A;  1GAI A;  3EQA A;  1KZO B;  5JPM B;  2H6G B;  3ANI A;  4KTR A;  1N20 A;  5ILZ A;  1NSV A;  1LXK A;  3E7J A;  3PQI A;  3EJR A;  3T08 A;  1HCU A;  4GTT B;  2B39 A;  1H12 A;  3DST B;  3A3V A;  3BVV A;  3K7X A;  4OZW A;  5EAU A;  3T0A A;  3VXD A;  1WU4 A;  3EU5 B;  5KKB A;  2XN0 A;  1QBQ B;  1MMZ A;  4BTW A;  5M7Y A;  3AMO A;  5JMD A;  1O7D D;  1N7N A;  4FNU A;  5FO7 B;  1YQ2 A;  2F1A A;  4D6G A;  2PMV A;  3WKI A;  3EUV B;  4FJQ A;  2FBA A;  3W7U A;  1F4A A;  1RWH A;  4FXK B;  1K1X A;  2X03 A;  2WMI B;  3ANK A;  1KRE A;  1DOG A;  2WY8 A;  1GAH A;  2E22 A;  4Z4L A;  1UMP A;  3BVX A;  1RWG A;  2XN2 A;  2JJB A;  1AVL A;  3Q7A B;  1LD8 B;  2QNO A;  2JF4 A;  2XHN A;  3DSX B;  2OOV C;  4LNB B;  3BVW A;  2G0D A;  2F0Y B;  4YDO B;  1XW2 A;  3HXF B;  1C82 A;  3QXF A;  2WGQ A;  2WW1 A;  2JKE A;  1NS7 A;  4D4C A;  1HZF A;  3KLS A;  4Z4J A;  3M77 A;  2CWV A;  2WMJ A;  1LVN A;  3Q75 B;  1N4R B;  3NNB A;  2JKP A;  1GHQ A;  1W6K A;  4L6X A;  1WMN A;  2EAC A;  2J5C A;  1HTY A;  3VSN A;  3WIR A;  3EJU A;  3DYO A;  3LOY A;  3DDF A;  1TQU A;  1N22 A;  4FNV A;  2FYV A;  1D8D B;  1QX1 A;  4KTP A;  3DPY B;  3EJS A;  4K35 A;  3HXE B;  1F9O A;  5IK0 A;  4AQ0 A;  1NS2 A;  3ANJ A;  2VN7 A;  3PMM A;  5IK6 A;  3D50 A;  4D6C A;  2AFA A;  3E73 A;  1QAK A;  1GXO A;  2KXS A;  3NBJ A;  3RX5 A;  3N0G A;  2RGK A;  3QG0 A;  1RQ5 A;  1UI8 A;  1JZ4 A;  4XUV A;  2BRW A;  1SIH A;  1K1W A;  1J0M A;  1RKY A;  4D94 A;  1H14 A;  1MMX A;  3EJQ A;  3IMH A;  3DRA B;  1TN8 B;  1N9A B;  1RWA A;  4JJJ A;  2C11 A;  3IAP A;  2D8L A;  3A0O A;  4DLO A;  1CB8 A;  1H39 A;  2V8K A;  1C3D A;  3D3I A;  2FUQ A;  2OKX A;  2Y73 A;  3WA3 A;  3OBA A;  1O1T B;  3PYA A;  1EKM A;  1IS9 A;  1G9J A;  2H6I B;  1DL2 A;  1N4P B;  2E24 A;  5AGD A;  3D4Y A;  1NSR A;  1N1Z A;  3K5T A;  2F18 A;  2WVZ A;  1D6Z A;  3WKF A;  1NS8 A;  3PYB A;  4E1Y A;  1O79 A;  2V3N A;  3VDC A;  2CFD A;  2OW7 A;  1S63 B;  3ACT A;  2CIS A;  1TXK A;  2OW6 A;  3SFY B;  3OS7 A;  1H35 A;  3M01 A;  4D8O A;  1JZ2 A;  4OZV A;  2CQT A;  2WMF A;  3BGA A;  4LNV A;  1IVU A;  3ALA A;  4BTY A;  4Q2B A;  4D4A A;  3WC3 A;  3VDA A;  1LOH A;  3F59 A;  2RI9 A;  3DX2 A;  2GOX A;  2WMH A;  3NJX A;  1MN0 A;  1L7J A;  1JYN A;  1N4S B;  4L9P B;  3AFJ A;  2CFW A;  1I8Q A;  4FNR A;  3RX8 A;  3H7L A;  1H37 A;  4KKJ A;  4DOD A;  1FT2 B;  3W7T A;  1X1H A;  4BZG A;  2FV1 A;  1S64 B;  2ZBL A;  2CIQ A;  2D1W A;  4GTO B;  4LNG B;  1FAE A;  1NC5 A;  3PZ2 B;  5M7I A;  5CZL A;  2H6F B;  2KXR A;  1NI1 B;  3KBT C;  1IVW A;  1JYV A;  1N7R A;  2WMG A;  1HN1 A;  3MWX A;  2WYH A;  3WVF A;  4KFF A;  3T2O A;  3M73 A;  2DRS A;  3MI6 A;  1O6H A;  3SDU A;  3HXB B;  3E6U A;  1FCE A;  3WKG A;  4GTM B;  1SO0 A;  3H2W A;  3EU8 A;  3E32 B;  2A73 B;  5C05 A;  2GH4 A;  4GTQ B;  3A24 A;  3BLB A;  1N24 A;  3VW5 A;  1Z45 A;  3T2P A;  3S9V A;  3HII A;  4GTV B;  4J5T A;  3D51 A;  3I3B A;  1F4H A;  3EZ8 A;  3GLY A;  3M71 A;  3Q1N A;  1KWF A;  1V5D A;  3M75 A;  3BUD A;  3DEC A;  4MMI A;  4YCR A;  3S4B A;  4AYQ A;  3QWT A;  3QRY A;  1NSX A;  1O6R A;  4MBG B;  5ILY A;  5IK9 A;  1JZ6 A;  3G4D A;  3CZJ A;  2ONH A;  1D6Y A;  1TQS A;  4AYP A;  1D8E B;  2JG0 A;  5JPN B;  3VD5 A;  1TQW A;  2D73 A;  2AHG A;  4OK4 A;  2BBC A;  1W6J A;  3WUX A;  3C72 B;  2Z07 A;  4BOK A;  2F1B A;  1KFG A;  1N7P A;  3DX0 A;  3GT5 A;  3IAQ A;  5GY3 A;  1FMI A;  3S4A A;  4D72 A;  1JZ3 A;  2F6D A;  4C1S A;  5DGR A;  2CG0 A;  3Q78 B;  3AMO B;  2XQW A;  3Q73 B;  3MUY 1;  3ACS A;  2WOF A;  3LZ9 A;  1EGU A;  1JYX A;  3EJP A;  1YGA A;  2OOV A;  1TNO B;  1IU7 A;  1J0N A;  1F9D A;  1G6I A;  4GAX A;  3DDG A;  3NBB A;  4V1S A;  4D6H A;  1JCR B;  3VD3 A;  3E80 A;  4CJ0 A;  1O1S B;  3ON6 A;  3W5N A;  1IA6 A;  3VDB A;  1O6Q A;  1HN0 A;  3KSL B;  1CEM A;  1FO2 A;  1JOV A;  5IM1 A;  1LD7 B;  3HI7 A;  2NOJ A;  1TU5 A;  1GLM A;  1PU4 A;  1RWF A;  1XWQ A;  2CIR A;  3CU7 A;  1MZC B;  1OJO A;  2CWT A;  3NRE A;  2ALW A;  2OQE C;  1SNZ A;  2RI8 A;  1PS3 A;  3TF4 A;  2WOH A;  5ILK A;  3G6J B;  2WCO A;  3D5S A;  5EAS A;  5CA3 A;  1WU5 A;  2H6H B;  3GZK A;  3KN4 A;  1KKT A;  4WU0 A;  1TNZ B;  1KS8 A;  1AV4 A;  3EJT A;  3KQ4 A;  5GZK A;  2AHF A;  1LUR A;  3M72 A;  1PX4 A;  4KFE A;  3X3X A;  2BT3 A;  1VD5 A;  4FUS A;  4KFD A;  1UT9 A;  1H3B A;  3OB8 A;  4FNP A;  1HWW A;  3VD4 A;  4OK2 A;  4AYO A;  2WVX B;  1V7W A;  2DRQ A;  3M00 A;  1F9G A;  1N4Q B;  1TF4 A;  1H54 A;  1NSU A;  2WIN B;  1N21 A;  1W4N A;  2FV0 A;  3E30 B;  1N1B A;  1TQV A;  4TF4 A;  3DYP A;  1KSC A;  4UFC A;  1JZ8 A;  3RSY A;  1DCE B;  4D6D A;  2CQS A;  3CIH A;  1DP0 A;  4V1R A;  1DYU A;  1RJO A;  2YFN A;  1HV6 A;  4YDE B;  2B4F A;  3W7W A;  3WIQ A;  3N0F A;  3X17 A;  3W7X A;  1HM2 A;  4KKI A;  2W0Q A;  2XWJ B;  1NS4 A;  1H36 A;  4CE7 A;  5E2J A;  1W6G A;  3W7S A;  1JCS B;  3D4Z A;  2ZZR A;  3BUQ A;  2CWU A;  3QT3 A;  3E34 B;  4DUV A;  2WYI A;  2E2U A;  1UG9 A;  1HMU A;  2XFG A;  3VD9 A;  2ONG A;  2CFK A;  2C10 A;  3X3Y A;  1QAZ A;  3X3Z A;  1TN7 B;  3DSS B;  1NL4 B;  2WMK A;  3SAE A;  3T33 A;  1US1 A;  3HXC B;  3X42 A;  4EHM B;  2XSG A;  3CV5 A;  3SEP A;  3X41 A;  3M78 A;  2BRV X;  4L0G A;  4RNQ A;  2P0V A;  5CD2 A;  3RX7 A;  3U7V A;  1R34 A;  1KZP B;  1NKG A;  3MUZ 1;  3UD2 A;  2F7O A;  4D6E A;  2D5J A;  1OJP A;  3MV0 1;  3VD7 A;  3NJV A;  2RDY A;  3PZ4 B;  5FO8 B;  2HTA A;  2WMI A;  3WA2 X;  4ZH1 A;  5A1A A;  3BUB A;  2I07 B;  1V7V A;  3BUP A;  4D4B A;  1L1Y A;  4D4D A;  1QWU A;  1KRF A;  1KSI A;  2E2V A;  4RNL A;  1TN6 B;  3G4F A;  4DI5 A;  3I3D A;  4TTG A;  4ONT A;  1IA7 A;  1JCQ B;  2BB6 A;  5ILD A;  1PX3 A;  2PNC A;  4GTR B;  3DCD A;  1X1I A;  4GTS B;  2Y74 A;  2YIK A;  1W6C A;  1W3Y A;  3H3K A; 
#chains in the Genus database with same CATH homology
 3IAP A;  1N7O A;  1LF9 A;  3A0O A;  3VSM A;  1YGA A;  1CB8 A;  1J0N A;  1ULV A;  2HTB A;  4D6H A;  3VD3 A;  3E80 A;  1OJN A;  3T2Q A;  2FUQ A;  3BLC A;  1HM3 A;  1RW9 A;  3OBA A;  3VDB A;  2WVY A;  1HN0 A;  3J7H A;  1K1Y A;  1JOV A;  2E24 A;  2WDA A;  2ZXQ A;  1L7K A;  2JKA A;  3DYM A;  1NSR A;  1RWF A;  2CIR A;  3NFV A;  1OJO A;  2WW0 A;  3NRE A;  1JZ3 A;  4F10 A;  1SNZ A;  1F1S A;  1HMW A;  2WVZ A;  1NS8 A;  1MMU A;  1LXM A;  4E1Y A;  3VDC A;  4NEI A;  2WCO A;  4D6J A;  1NSM A;  1OJM A;  4BZH A;  4F13 A;  2CIS A;  2WW2 A;  1NS0 A;  1TXK A;  1PX4 A;  3T09 A;  1LUR A;  1JZ7 A;  3OS7 A;  2WVX A;  1JZ2 A;  4OZV A;  2WMF A;  5JMF A;  3BGA A;  4DUX A;  3TY1 A;  1NSV A;  1LXK A;  3E7J A;  3OB8 A;  3T08 A;  3VD4 A;  4OK2 A;  4MMH A;  2WVX B;  3VDA A;  1F9G A;  1LOH A;  1MMY A;  2ZQ0 A;  1NSU A;  1JYW A;  4OZW A;  3T0A A;  5E1Q A;  2WMH A;  3BS6 A;  1MN0 A;  1L7J A;  3NJX A;  3WFA A;  1MMZ A;  3DYP A;  1JYN A;  5JMD A;  1JZ8 A;  1N7N A;  1I8Q A;  4BZG A;  1YQ2 A;  4D6D A;  2WZS A;  1X1H A;  1DP0 A;  4D6G A;  3MV1 1;  1HV6 A;  2CIQ A;  1RWC A;  1RWH A;  1F4A A;  1K1X A;  1HM2 A;  4OJZ A;  2X03 A;  1NS4 A;  2WMI B;  2BRP A;  2E22 A;  1JYV A;  1N7R A;  2WMG A;  1NSZ A;  1RWG A;  1HN1 A;  3MWX A;  3WVF A;  3E1F 1;  4DUV A;  2XHN A;  3AFL A;  3T2O A;  4D6F A;  1UG9 A;  1HMU A;  1C82 A;  1SO0 A;  4DUW A;  2WW1 A;  2JKE A;  3VD9 A;  1NS7 A;  3A24 A;  1QAZ A;  2Q1F A;  1Z45 A;  2WMK A;  1X1J A;  3T2P A;  4BZE A;  2WMJ A;  3I3B A;  4J5T A;  3I3E A;  1F4H A;  4BZF A;  3NNB A;  2JKP A;  3Q1N A;  1N7Q A;  2XSG A;  2WW3 A;  3VSN A;  3SEP A;  4D71 A;  3DYO A;  1LF6 A;  2BRV X;  4FNV A;  4MMI A;  3DEC A;  1JZ5 A;  1NSX A;  3K25 A;  1NKG A;  4AQ0 A;  3MUZ 1;  1JZ6 A;  1NS2 A;  3CZJ A;  4D6C A;  4D6E A;  3VD7 A;  1OJP A;  3MV0 1;  3T0D A;  3NJV A;  1NSS A;  3VD5 A;  2HTA A;  2D73 A;  4OK4 A;  2WMI A;  5A1A A;  1JZ4 A;  4RNL A;  2BRW A;  1N7P A;  3T0B A;  1K1W A;  3IAQ A;  1J0M A;  3I3D A;  4TTG A;  1PX3 A;  1MMX A;  3IMH A;  4D72 A;  3DCD A;  1X1I A;  3MUY 1;  4D6I A;  3ECQ A;  2FUT A;  1RWA A;  1JYX A;  1W3Y A;  1EGU A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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