2BXCA

Human serum albumin complexed with phenylbutazone
Total Genus 205
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
205
sequence length
578
structure length
578
Chain Sequence
SEVAHRFKDLGEENFKALVLIAFAQYLQQCPFEDHVKLVNEVTEFAKTCVADESAENCDKSLHTLFGDKLCTVATLRETYGEMADCCAKQEPERNECFLQHKDDNPNLPRLVRPEVDVMCTAFHDNEETFLKKYLYEIARRHPYFYAPELLFFAKRYKAAFTECCQAADKAACLLPKLDELRDEGKASSAKQRLKCASLQKFGERAFKAWAVARLSQRFPKAEFAEVSKLVTDLTKVHTECCHGDLLECADDRADLAKYICENQDSISSKLKECCEKPLLEKSHCIAEVENDEMPADLPSLAADFVESKDVCKNYAEAKDVFLGMFLYEYARRHPDYSVVLLLRLAKTYETTLEKCCAAADPHECYAKVFDEFKPLVEEPQNLIKQNCELFEQLGEYKFQNALLVRYTKKVPQVSTPTLVEVSRNLGKVGSKCCKHPEAKRMPCAEDYLSVVLNQLCVLHEKTPVSDRVTKCCTESLVNRRPCFSALEVDETYVPKEFNAETFTFHADICTLSEKERQIKKQTALVELVKHKPKATKEQLKAVMDDFAAFVEKCCKADDKETCFAEEGKKLVAASQAA
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule keywords SERUM ALBUMIN
publication title Structural Basis of the Drug-Binding Specificity of Human Serum Albumin.
pubmed doi rcsb
source organism Homo sapiens
molecule tags Transport protein
total genus 205
structure length 578
sequence length 578
chains with identical sequence B
ec nomenclature
pdb deposition date 2005-07-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00273 Serum_albumin Serum albumin family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 2bxcA03
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 2bxcA02
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 2bxcA04
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 2bxcA01
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 2bxcA06
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 2bxcA05
2BXLA 1BJ5A 4E99A 4N0UD 4N0FD 5IJFA 3JQZA 4G03A 4G04A 1E78A 5IFOA 4F5TA 1E7GA 5DQFA 2BXFA 4J2VA 5IJEA 1O9XA 3SQJA 1E7CA 4IW2A 3LU8A 1E7EA 2BXBA 2BXGA 4IW1A 5ID9A 1AO6A 2YDFA 2VDBA 2XVVA 1GNIA 1LOTA 3V08A 4LA0A 5IJ5A 2BXCA 3LU6A 4LUHA 3LU7A 2XW1A 2BXDA 5ID7A 4HGMB 2VUEA 1HK5A 2XSIA 3B9LA 4K2CA 3TDLA 2XVUA 4Z69A 2BXNA 1BM0A 2BXPA 2BXIA 4OR0A 4L9QA 4PO0A 4S1YA 1E7FA 4LUFA 4EMXA 4LB2A 4F5SA 2BXEA 1KW2A 1N5UA 4L8UA 1H9ZA 3V09A 2BXKA 2XVWA 2BX8A 1KXPD 4K71A 5IIXA 1TF0A 2VUFA 1HK4A 5FUOA 1GNJA 4ZBRA 2I2ZA 1E7HA 1E7AA 4F5VA 2BXQA 3CX9A 2BXAA 1HK2A 4OT2A 2I30A 2BXMA 5IIHA 5HOZA 3A73A 1J7EA 1HK3A 1E7IA 2BXHA 1J78A 4HGKA 2XW0A 3JRYA 1E7BA 5DBYA 4ZBQA 4BKEA 1MA9A 4LB9A 1BKEA 4F5UA 4JK4A 4L9KA 1HA2A 3B9MA 3UIVA 1UORA 3V03A 2BXOA 5GHKA 1HK1A 2XVQA 5IIUA
chains in the Genus database with same CATH superfamily
2BXLA 4D7XA 1BJ5A 1JNBA 4E99A 4G01A 4N0UD 1KDXA 4N0FD 4DHXB 5IJFA 3JQZA 3GA9L 2NNWA 3KIKA 1MIYA 4G03A 1E78A 4G04A 5IFOA 4TQ1A 4F5TA 1E7GA 2ROHA 3MHSB 3FNMA 5DQFA 2DYMA 4MBEC 2BXFA 2E0XA 4J2VA 5IJEA 2DBXA 5GINA 2AGHB 1O9XA 3GQXA 1E7CA 4GDKB 3SQJA 4IW2A 2KWFA 3LU8A 4GG2A 3SIUB 3ECPA 1IJGA 2OT3A 1E7EA 3FWCC 2BXBA 3H37A 2BXGA 3BPJA 2QHBA 4IW1A 4TQ0A 5ID9A 1AO6A 2DYOA 2YDFA 4OTTA 3WHRA 2VDBA 3NMUA 1SB0A 2XVVA 4FK5B 1MUSA 2K0NA 1MIWA 2DBWA 1GNIA 1LOTA 2JUHA 3V08A 4LA0A 5IJ5A 2BXCA 3LU6A 4LUHA 5D7GA 3LU7A 1MM8A 2V36A 2XW1A 3NVKA 4N3ZA 2BXDA 1TXUA 2LXSA 2Z8JA 1FOUA 5ID7A 4HGMB 1MUHA 2VUEA 1HK5A 4Z9OA 1VFIA 2XSIA 3B9LA 4GDXA 1LNSA 4K2CA 3TDLA 2XVUA 4Z69A 2BXNA 3NVMA 3WHQA 3NVIA 1BM0A 2BXPA 2BXIA 2DBUA 4OR0A 4L9QA 4PO0A 2OZBB 4S1YA 1E7FA 4LUFA 3KJLA 4EMXA 3WHSA 4I9OA 5B5TA 4LB2A 4F5SA 2BXEA 1KW2A 4ZUXV 2E0YA 1NT2B 1N5UA 2LOQA 2GUTA 4L8UA 2CKXA 1H9ZA 3V09A 2BXKA 3GQUA 4W4UB 2XVWA 4DM0A 2BX8A 2XMOA 4NAWB 2EFEA 4ZC6A 3PLAA 4FIPB 1KXPD 3MHHB 4K71A 5IIXA 4ZBKA 2EFHA 5BPKA 1TF0A 2VUFA 1HK4A 3ICXA 1H5WA 5FUOA 1GNJA 4ZBRA 2I2ZA 1E7HA 2LQIA 1E7AA 4F5VA 2BXQA 3CX9A 5GIOA 2LXTA 2BXAA 4ZCGA 2KBZA 1HK2A 3A75A 4OT2A 2NQOA 3SIVB 3FWBC 4OTUA 2DG5A 2I30A 3H3AA 2BXMA 5IIHA 5HOZA 3W1SA 4WA6B 3A73A 1J7EA 1HK3A 2QM6A 1E7IA 2BXHA 1J78A 4HGKA 2XW0A 1VZSA 2EFDA 3JRYA 3VQIA 1E7BA 5DBYA 4ZBQA 4M70B 4BKEA 1MA9A 4LB9A 1MIVA 1BKEA 3G9KD 4FJCB 4C31B 3M99C 4F5UA 4JK4A 2AJEA 2EFCA 4L9KA 5GIPA 1HA2A 3B9MA 3UIVA 1UORA 2QMCA 4GDLB 3V03A 2BXOA 2LQHA 5GHKA 2Z8IA 1HK1A 4BY9C 2Z8KA 2XVQA 5IIUA
chains in the Genus database with same CATH topology
2BXLA 1BJ5A 1JNBA 4E99A 4G01A 4N0UD 4N0FD 4DHXB 5IJFA 3JQZA 3GA9L 2NNWA 3KIKA 1MIYA 4G03A 1E78A 4G04A 5IFOA 4TQ1A 4F5TA 1E7GA 2ROHA 3MHSB 3FNMA 5DQFA 2DYMA 4MBEC 2BXFA 2E0XA 4J2VA 5IJEA 2DBXA 5GINA 1O9XA 3GQXA 1E7CA 4GDKB 3SQJA 4IW2A 3LU8A 4GG2A 3SIUB 1IJGA 2OT3A 1E7EA 3FWCC 2BXBA 3H37A 2BXGA 2QHBA 4IW1A 4TQ0A 5ID9A 1AO6A 2DYOA 2YDFA 4OTTA 3WHRA 2VDBA 3NMUA 2XVVA 4FK5B 1MIWA 2DBWA 1GNIA 1LOTA 2JUHA 3V08A 4LA0A 5IJ5A 2BXCA 3LU6A 4LUHA 5D7GA 3LU7A 2V36A 2XW1A 3NVKA 4N3ZA 2BXDA 1TXUA 2Z8JA 1FOUA 5ID7A 4HGMB 2VUEA 1HK5A 4Z9OA 1VFIA 2XSIA 3B9LA 4GDXA 1LNSA 4K2CA 3TDLA 2XVUA 4Z69A 2BXNA 3NVMA 3WHQA 3NVIA 1BM0A 2BXPA 2BXIA 2DBUA 4OR0A 4L9QA 4PO0A 2OZBB 4S1YA 1E7FA 4LUFA 3KJLA 4EMXA 3WHSA 5B5TA 4LB2A 4F5SA 2BXEA 1KW2A 4ZUXV 2E0YA 1NT2B 1N5UA 2LOQA 4L8UA 2CKXA 1H9ZA 3V09A 2BXKA 3GQUA 4W4UB 2XVWA 2BX8A 2XMOA 4NAWB 2EFEA 4ZC6A 3PLAA 4FIPB 1KXPD 3MHHB 4K71A 5IIXA 4ZBKA 2EFHA 5BPKA 1TF0A 2VUFA 1HK4A 3ICXA 1H5WA 5FUOA 1GNJA 4ZBRA 2I2ZA 1E7HA 1E7AA 4F5VA 2BXQA 3CX9A 5GIOA 2BXAA 4ZCGA 2KBZA 1HK2A 3A75A 4OT2A 2NQOA 3SIVB 3FWBC 4OTUA 2DG5A 2I30A 3H3AA 2BXMA 5IIHA 5HOZA 3W1SA 4WA6B 3A73A 1J7EA 1HK3A 2QM6A 1E7IA 2BXHA 1J78A 4HGKA 2XW0A 1VZSA 2EFDA 3JRYA 3VQIA 1E7BA 5DBYA 4ZBQA 4M70B 4BKEA 1MA9A 4LB9A 1MIVA 1BKEA 3G9KD 4FJCB 4C31B 3M99C 4F5UA 4JK4A 2AJEA 2EFCA 4L9KA 5GIPA 1HA2A 3B9MA 3UIVA 1UORA 2QMCA 4GDLB 3V03A 2BXOA 5GHKA 2Z8IA 1HK1A 4BY9C 2Z8KA 2XVQA 5IIUA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2BXL A;  1BJ5 A;  4E99 A;  4N0U D;  4N0F D;  5IJF A;  3JQZ A;  4G03 A;  4G04 A;  1E78 A;  5IFO A;  4F5T A;  1E7G A;  5DQF A;  2BXF A;  4J2V A;  5IJE A;  1O9X A;  3SQJ A;  1E7C A;  4IW2 A;  3LU8 A;  1E7E A;  2BXB A;  2BXG A;  4IW1 A;  5ID9 A;  1AO6 A;  2YDF A;  2VDB A;  2XVV A;  1GNI A;  1LOT A;  3V08 A;  4LA0 A;  5IJ5 A;  2BXC A;  3LU6 A;  4LUH A;  3LU7 A;  2XW1 A;  2BXD A;  5ID7 A;  4HGM B;  2VUE A;  1HK5 A;  2XSI A;  3B9L A;  4K2C A;  3TDL A;  2XVU A;  4Z69 A;  2BXN A;  1BM0 A;  2BXP A;  2BXI A;  4OR0 A;  4L9Q A;  4PO0 A;  4S1Y A;  1E7F A;  4LUF A;  4EMX A;  4LB2 A;  4F5S A;  2BXE A;  1KW2 A;  1N5U A;  4L8U A;  1H9Z A;  3V09 A;  2BXK A;  2XVW A;  2BX8 A;  1KXP D;  4K71 A;  5IIX A;  1TF0 A;  2VUF A;  1HK4 A;  5FUO A;  1GNJ A;  4ZBR A;  2I2Z A;  1E7H A;  1E7A A;  4F5V A;  2BXQ A;  3CX9 A;  2BXA A;  1HK2 A;  4OT2 A;  2I30 A;  2BXM A;  5IIH A;  5HOZ A;  3A73 A;  1J7E A;  1HK3 A;  1E7I A;  2BXH A;  1J78 A;  4HGK A;  2XW0 A;  3JRY A;  1E7B A;  5DBY A;  4ZBQ A;  4BKE A;  1MA9 A;  4LB9 A;  1BKE A;  4F5U A;  4JK4 A;  4L9K A;  1HA2 A;  3B9M A;  3UIV A;  1UOR A;  3V03 A;  2BXO A;  5GHK A;  1HK1 A;  2XVQ A;  5IIU A; 
#chains in the Genus database with same CATH topology
 2BXL A;  4D7X A;  1BJ5 A;  1JNB A;  4E99 A;  4G01 A;  4N0U D;  1KDX A;  4N0F D;  4DHX B;  5IJF A;  3JQZ A;  3GA9 L;  2NNW A;  3KIK A;  1MIY A;  4G03 A;  1E78 A;  4G04 A;  5IFO A;  4TQ1 A;  4F5T A;  1E7G A;  2ROH A;  3MHS B;  3FNM A;  5DQF A;  2DYM A;  4MBE C;  2BXF A;  2E0X A;  4J2V A;  5IJE A;  2DBX A;  5GIN A;  2AGH B;  1O9X A;  3GQX A;  1E7C A;  4GDK B;  3SQJ A;  4IW2 A;  2KWF A;  3LU8 A;  4GG2 A;  3SIU B;  3ECP A;  1IJG A;  2OT3 A;  1E7E A;  3FWC C;  2BXB A;  3H37 A;  2BXG A;  3BPJ A;  2QHB A;  4IW1 A;  4TQ0 A;  5ID9 A;  1AO6 A;  2DYO A;  2YDF A;  4OTT A;  3WHR A;  2VDB A;  3NMU A;  1SB0 A;  2XVV A;  4FK5 B;  1MUS A;  2K0N A;  1MIW A;  2DBW A;  1GNI A;  1LOT A;  2JUH A;  3V08 A;  4LA0 A;  5IJ5 A;  2BXC A;  3LU6 A;  4LUH A;  5D7G A;  3LU7 A;  1MM8 A;  2V36 A;  2XW1 A;  3NVK A;  4N3Z A;  2BXD A;  1TXU A;  2LXS A;  2Z8J A;  1FOU A;  5ID7 A;  4HGM B;  1MUH A;  2VUE A;  1HK5 A;  4Z9O A;  1VFI A;  2XSI A;  3B9L A;  4GDX A;  1LNS A;  4K2C A;  3TDL A;  2XVU A;  4Z69 A;  2BXN A;  3NVM A;  3WHQ A;  3NVI A;  1BM0 A;  2BXP A;  2BXI A;  2DBU A;  4OR0 A;  4L9Q A;  4PO0 A;  2OZB B;  4S1Y A;  1E7F A;  4LUF A;  3KJL A;  4EMX A;  3WHS A;  4I9O A;  5B5T A;  4LB2 A;  4F5S A;  2BXE A;  1KW2 A;  4ZUX V;  2E0Y A;  1NT2 B;  1N5U A;  2LOQ A;  2GUT A;  4L8U A;  2CKX A;  1H9Z A;  3V09 A;  2BXK A;  3GQU A;  4W4U B;  2XVW A;  4DM0 A;  2BX8 A;  2XMO A;  4NAW B;  2EFE A;  4ZC6 A;  3PLA A;  4FIP B;  1KXP D;  3MHH B;  4K71 A;  5IIX A;  4ZBK A;  2EFH A;  5BPK A;  1TF0 A;  2VUF A;  1HK4 A;  3ICX A;  1H5W A;  5FUO A;  1GNJ A;  4ZBR A;  2I2Z A;  1E7H A;  2LQI A;  1E7A A;  4F5V A;  2BXQ A;  3CX9 A;  5GIO A;  2LXT A;  2BXA A;  4ZCG A;  2KBZ A;  1HK2 A;  3A75 A;  4OT2 A;  2NQO A;  3SIV B;  3FWB C;  4OTU A;  2DG5 A;  2I30 A;  3H3A A;  2BXM A;  5IIH A;  5HOZ A;  3W1S A;  4WA6 B;  3A73 A;  1J7E A;  1HK3 A;  2QM6 A;  1E7I A;  2BXH A;  1J78 A;  4HGK A;  2XW0 A;  1VZS A;  2EFD A;  3JRY A;  3VQI A;  1E7B A;  5DBY A;  4ZBQ A;  4M70 B;  4BKE A;  1MA9 A;  4LB9 A;  1MIV A;  1BKE A;  3G9K D;  4FJC B;  4C31 B;  3M99 C;  4F5U A;  4JK4 A;  2AJE A;  2EFC A;  4L9K A;  5GIP A;  1HA2 A;  3B9M A;  3UIV A;  1UOR A;  2QMC A;  4GDL B;  3V03 A;  2BXO A;  2LQH A;  5GHK A;  2Z8I A;  1HK1 A;  4BY9 C;  2Z8K A;  2XVQ A;  5IIU A; 
#chains in the Genus database with same CATH homology
 2BXL A;  1BJ5 A;  1JNB A;  4E99 A;  4G01 A;  4N0U D;  4N0F D;  4DHX B;  5IJF A;  3JQZ A;  3GA9 L;  2NNW A;  3KIK A;  1MIY A;  4G03 A;  1E78 A;  4G04 A;  5IFO A;  4TQ1 A;  4F5T A;  1E7G A;  2ROH A;  3MHS B;  3FNM A;  5DQF A;  2DYM A;  4MBE C;  2BXF A;  2E0X A;  4J2V A;  5IJE A;  2DBX A;  5GIN A;  1O9X A;  3GQX A;  1E7C A;  4GDK B;  3SQJ A;  4IW2 A;  3LU8 A;  4GG2 A;  3SIU B;  1IJG A;  2OT3 A;  1E7E A;  3FWC C;  2BXB A;  3H37 A;  2BXG A;  2QHB A;  4IW1 A;  4TQ0 A;  5ID9 A;  1AO6 A;  2DYO A;  2YDF A;  4OTT A;  3WHR A;  2VDB A;  3NMU A;  2XVV A;  4FK5 B;  1MIW A;  2DBW A;  1GNI A;  1LOT A;  2JUH A;  3V08 A;  4LA0 A;  5IJ5 A;  2BXC A;  3LU6 A;  4LUH A;  5D7G A;  3LU7 A;  2V36 A;  2XW1 A;  3NVK A;  4N3Z A;  2BXD A;  1TXU A;  2Z8J A;  1FOU A;  5ID7 A;  4HGM B;  2VUE A;  1HK5 A;  4Z9O A;  1VFI A;  2XSI A;  3B9L A;  4GDX A;  1LNS A;  4K2C A;  3TDL A;  2XVU A;  4Z69 A;  2BXN A;  3NVM A;  3WHQ A;  3NVI A;  1BM0 A;  2BXP A;  2BXI A;  2DBU A;  4OR0 A;  4L9Q A;  4PO0 A;  2OZB B;  4S1Y A;  1E7F A;  4LUF A;  3KJL A;  4EMX A;  3WHS A;  5B5T A;  4LB2 A;  4F5S A;  2BXE A;  1KW2 A;  4ZUX V;  2E0Y A;  1NT2 B;  1N5U A;  2LOQ A;  4L8U A;  2CKX A;  1H9Z A;  3V09 A;  2BXK A;  3GQU A;  4W4U B;  2XVW A;  2BX8 A;  2XMO A;  4NAW B;  2EFE A;  4ZC6 A;  3PLA A;  4FIP B;  1KXP D;  3MHH B;  4K71 A;  5IIX A;  4ZBK A;  2EFH A;  5BPK A;  1TF0 A;  2VUF A;  1HK4 A;  3ICX A;  1H5W A;  5FUO A;  1GNJ A;  4ZBR A;  2I2Z A;  1E7H A;  1E7A A;  4F5V A;  2BXQ A;  3CX9 A;  5GIO A;  2BXA A;  4ZCG A;  2KBZ A;  1HK2 A;  3A75 A;  4OT2 A;  2NQO A;  3SIV B;  3FWB C;  4OTU A;  2DG5 A;  2I30 A;  3H3A A;  2BXM A;  5IIH A;  5HOZ A;  3W1S A;  4WA6 B;  3A73 A;  1J7E A;  1HK3 A;  2QM6 A;  1E7I A;  2BXH A;  1J78 A;  4HGK A;  2XW0 A;  1VZS A;  2EFD A;  3JRY A;  3VQI A;  1E7B A;  5DBY A;  4ZBQ A;  4M70 B;  4BKE A;  1MA9 A;  4LB9 A;  1MIV A;  1BKE A;  3G9K D;  4FJC B;  4C31 B;  3M99 C;  4F5U A;  4JK4 A;  2AJE A;  2EFC A;  4L9K A;  5GIP A;  1HA2 A;  3B9M A;  3UIV A;  1UOR A;  2QMC A;  4GDL B;  3V03 A;  2BXO A;  5GHK A;  2Z8I A;  1HK1 A;  4BY9 C;  2Z8K A;  2XVQ A;  5IIU A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...