2BXHA

Human serum albumin complexed with indoxyl sulfate
Total Genus 206
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
206
sequence length
557
structure length
557
Chain Sequence
SEVAHRFKDLGEENFKALVLIAFAQYLQQCPFEDHVKLVNEVTEFAKTCVADESAENCDKSLHTLFGDKLCTVATLRETYGEMADCCAKQEPERNECFLQHKDDNPNLPRLVRPEVDVMCTAFHDNEETFLKKYLYEIARRHPYFYAPELLFFAKRYKAAFTECCQAADKAACLLPKLDELRDEGKASSAKQRLKCASLQKFGERAFKAWAVARLSQRFPKAEFAEVSKLVTDLTKVHTECCHGDLLECADDRADLAKYICENQDSISSKLKECCEKPLLEKSHCIAEVENDEMPADLPSLAADFVESKDVCKNYAEAKDVFLGMFLYEYARRHPDYSVVLLLRLAKTYETTLEKCCAAADPHECYAKVFDEFKPLVEEPQNLIKQNCELFEQLGEYKFQNALLVRYTKKVPQVSTPTLVEVSRNLGKVGSKCCKHPEAKRMPCAEDYLSVVLNQLCVLHEKTPVSDRVTKCCTESLVNRRPCFSALEVDETYVPKEFNAETFTFHADICTLSEKERQIKKQTALVELVKHKPKATKEQLKAVMDDFAAFVEKCCKA
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structural Basis of the Drug-Binding Specificity of Human Serum Albumin.
pubmed doi rcsb
molecule keywords SERUM ALBUMIN
molecule tags Transport protein
source organism Homo sapiens
total genus 206
structure length 557
sequence length 557
chains with identical sequence B
ec nomenclature
pdb deposition date 2005-07-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00273 Serum_albumin Serum albumin family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 2bxhA03
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 2bxhA02
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 2bxhA04
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 2bxhA01
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 2bxhA05
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 2bxhA06
1HK3A 4BKEA 5DBYA 1BJ5A 2BXBA 2BXLA 4F5TA 3V08A 4LA0A 1BKEA 5FUOA 1E7IA 5IIHA 4ZBQA 1O9XA 3A73A 1GNJA 1E7FA 4ZBRA 4E99A 4F5VA 4HGMB 1KXPD 2XVQA 2YDFA 5IJFA 3LU8A 3B9LA 4K2CA 3V09A 3JQZA 2BX8A 5GHKA 2XVUA 3UIVA 1E78A 4PO0A 2XW0A 4N0UD 1GNIA 1BM0A 1N5UA 4HGKA 4JK4A 1HA2A 1MA9A 1HK4A 2BXFA 2VDBA 4L8UA 4F5SA 2BXMA 2BXQA 2XW1A 2I30A 3LU7A 2BXAA 2XVWA 2XSIA 4EMXA 1LOTA 1E7GA 1TF0A 3V03A 4IW2A 3SQJA 1KW2A 2BXKA 2BXCA 2XVVA 5DQFA 3JRYA 1HK1A 3LU6A 1AO6A 2BXPA 2BXOA 5ID7A 2BXIA 4G03A 2BXGA 1HK2A 4LUFA 4L9QA 4OT2A 1J78A 1UORA 4J2VA 1E7CA 4LB9A 4LUHA 5IIUA 3TDLA 5ID9A 4F5UA 2BXNA 1J7EA 2VUEA 1E7BA 2VUFA 5IFOA 5HOZA 1E7EA 2BXDA 4S1YA 4IW1A 5IIXA 1HK5A 2BXHA 5IJ5A 3B9MA 4L9KA 5IJEA 2I2ZA 4K71A 2BXEA 3CX9A 4G04A 4N0FD 4OR0A 1E7HA 1E7AA 4Z69A 4LB2A 1H9ZA
chains in the Genus database with same CATH superfamily
2GUTA 5D7GA 4TQ1A 2QMCA 1HK3A 4BKEA 3H37A 3ECPA 3KIKA 3A75A 4ZC6A 3NMUA 5DBYA 2EFHA 1BJ5A 2BXBA 2BXLA 4F5TA 3V08A 1MIYA 4OTTA 1NT2B 4LA0A 1BKEA 2XMOA 2LXSA 4M70B 4ZBKA 3M99C 4GDXA 5FUOA 1JNBA 1E7IA 2JUHA 5IIHA 4ZBQA 3W1SA 1O9XA 3FWBC 1LNSA 3A73A 1IJGA 2DBWA 5B5TA 1GNJA 3ICXA 1E7FA 1VZSA 4ZBRA 3BPJA 2LXTA 5GIPA 4E99A 4F5VA 2QHBA 4HGMB 1KXPD 4FIPB 3PLAA 3KJLA 2XVQA 1FOUA 2YDFA 2KBZA 4MBEC 5IJFA 1MIVA 3LU8A 3B9LA 4K2CA 4W4UB 3JQZA 3H3AA 4OTUA 3V09A 1KDXA 4GG2A 2CKXA 2BX8A 1MIWA 1H5WA 2XVUA 5GHKA 4GDKB 3UIVA 1E78A 3SIUB 4PO0A 2XW0A 4N0UD 3NVKA 2DBXA 1GNIA 1BM0A 5GIOA 2LQIA 1N5UA 4HGKA 4JK4A 2LQHA 1HA2A 1MA9A 2AGHB 1HK4A 3G9KD 2BXFA 2VDBA 5BPKA 4L8UA 3WHRA 4ZCGA 4DM0A 4F5SA 2BXMA 2BXQA 2XW1A 2EFEA 5GINA 4Z9OA 4C31B 2I30A 2K0NA 3LU7A 3NVMA 2BXAA 4N3ZA 2XVWA 2XSIA 2OZBB 3WHSA 4EMXA 1LOTA 1E7GA 1TF0A 4GDLB 3V03A 4IW2A 2ROHA 3FWCC 3SQJA 1KW2A 2BXKA 2DBUA 2Z8KA 2BXCA 3GQXA 2E0YA 4FJCB 2XVVA 5DQFA 3JRYA 1HK1A 3LU6A 1AO6A 1MUSA 3GQUA 4NAWB 2BXPA 2BXOA 5ID7A 2BXIA 4G03A 2BXGA 1HK2A 4LUFA 1MM8A 4BY9C 2E0XA 4L9QA 4OT2A 1J78A 1UORA 4J2VA 1E7CA 3MHSB 3SIVB 3FNMA 4LB9A 4LUHA 2Z8IA 4I9OA 3VQIA 2LOQA 2KWFA 5IIUA 3TDLA 4FK5B 4F5UA 5ID9A 2V36A 2BXNA 1J7EA 2VUEA 1E7BA 2VUFA 5IFOA 5HOZA 3GA9L 2Z8JA 4WA6B 2NQOA 1E7EA 2BXDA 2DYMA 2EFDA 4G01A 4IW1A 4S1YA 3MHHB 1HK5A 5IIXA 2QM6A 2AJEA 2BXHA 5IJ5A 1VFIA 2NNWA 3B9MA 4DHXB 4L9KA 5IJEA 3WHQA 4D7XA 2I2ZA 4TQ0A 4K71A 2BXEA 3CX9A 4G04A 2DG5A 1SB0A 1TXUA 2EFCA 1MUHA 4N0FD 4OR0A 1E7HA 4ZUXV 1E7AA 2OT3A 2DYOA 3NVIA 4Z69A 4LB2A 1H9ZA
chains in the Genus database with same CATH topology
5D7GA 4TQ1A 2QMCA 1HK3A 4BKEA 3H37A 3KIKA 3A75A 4ZC6A 3NMUA 5DBYA 2EFHA 1BJ5A 2BXBA 2BXLA 4F5TA 3V08A 1MIYA 4OTTA 1NT2B 4LA0A 1BKEA 2XMOA 4ZBKA 4M70B 3M99C 4GDXA 5FUOA 1JNBA 1E7IA 2JUHA 5IIHA 4ZBQA 3W1SA 1O9XA 3FWBC 1LNSA 3A73A 1IJGA 2DBWA 5B5TA 1GNJA 3ICXA 1E7FA 1VZSA 4ZBRA 5GIPA 4E99A 4F5VA 2QHBA 4HGMB 1KXPD 4FIPB 3PLAA 3KJLA 2XVQA 1FOUA 2YDFA 2KBZA 4MBEC 5IJFA 1MIVA 3LU8A 3B9LA 4K2CA 4W4UB 3JQZA 3H3AA 4OTUA 3V09A 4GG2A 2CKXA 2BX8A 1MIWA 1H5WA 2XVUA 5GHKA 4GDKB 3UIVA 1E78A 3SIUB 4PO0A 2XW0A 4N0UD 3NVKA 2DBXA 1GNIA 1BM0A 5GIOA 1N5UA 4HGKA 4JK4A 1HA2A 1MA9A 3G9KD 1HK4A 5BPKA 2BXFA 2VDBA 4L8UA 3WHRA 4ZCGA 4F5SA 2BXMA 2BXQA 2XW1A 2EFEA 5GINA 4Z9OA 4C31B 2I30A 3LU7A 3NVMA 2BXAA 4N3ZA 2XVWA 2XSIA 2OZBB 3WHSA 4EMXA 1LOTA 1E7GA 1TF0A 4GDLB 3V03A 4IW2A 2ROHA 3FWCC 3SQJA 1KW2A 2BXKA 2DBUA 2Z8KA 2BXCA 3GQXA 2E0YA 4FJCB 2XVVA 5DQFA 3JRYA 1HK1A 3LU6A 1AO6A 3GQUA 4NAWB 2BXPA 2BXOA 5ID7A 2BXIA 4G03A 2BXGA 1HK2A 4LUFA 4BY9C 2E0XA 4L9QA 4OT2A 1J78A 1UORA 4J2VA 1E7CA 3MHSB 3SIVB 3FNMA 4LB9A 4LUHA 2Z8IA 3VQIA 5IIUA 2LOQA 3TDLA 4FK5B 4F5UA 5ID9A 2V36A 2BXNA 1J7EA 2VUEA 1E7BA 2VUFA 5IFOA 5HOZA 3GA9L 2Z8JA 4WA6B 2NQOA 1E7EA 2BXDA 2DYMA 2EFDA 4G01A 4IW1A 4S1YA 3MHHB 1HK5A 5IIXA 2QM6A 2AJEA 2BXHA 5IJ5A 1VFIA 2NNWA 3B9MA 4DHXB 4L9KA 5IJEA 3WHQA 2I2ZA 4TQ0A 4K71A 2BXEA 3CX9A 4G04A 2DG5A 1TXUA 2EFCA 4N0FD 4OR0A 1E7HA 4ZUXV 1E7AA 2OT3A 2DYOA 3NVIA 4Z69A 4LB2A 1H9ZA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1HK3 A;  4BKE A;  5DBY A;  1BJ5 A;  2BXB A;  2BXL A;  4F5T A;  3V08 A;  4LA0 A;  1BKE A;  5FUO A;  1E7I A;  5IIH A;  4ZBQ A;  1O9X A;  3A73 A;  1GNJ A;  1E7F A;  4ZBR A;  4E99 A;  4F5V A;  4HGM B;  1KXP D;  2XVQ A;  2YDF A;  5IJF A;  3LU8 A;  3B9L A;  4K2C A;  3V09 A;  3JQZ A;  2BX8 A;  5GHK A;  2XVU A;  3UIV A;  1E78 A;  4PO0 A;  2XW0 A;  4N0U D;  1GNI A;  1BM0 A;  1N5U A;  4HGK A;  4JK4 A;  1HA2 A;  1MA9 A;  1HK4 A;  2BXF A;  2VDB A;  4L8U A;  4F5S A;  2BXM A;  2BXQ A;  2XW1 A;  2I30 A;  3LU7 A;  2BXA A;  2XVW A;  2XSI A;  4EMX A;  1LOT A;  1E7G A;  1TF0 A;  3V03 A;  4IW2 A;  3SQJ A;  1KW2 A;  2BXK A;  2BXC A;  2XVV A;  5DQF A;  3JRY A;  1HK1 A;  3LU6 A;  1AO6 A;  2BXP A;  2BXO A;  5ID7 A;  2BXI A;  4G03 A;  2BXG A;  1HK2 A;  4LUF A;  4L9Q A;  4OT2 A;  1J78 A;  1UOR A;  4J2V A;  1E7C A;  4LB9 A;  4LUH A;  5IIU A;  3TDL A;  5ID9 A;  4F5U A;  2BXN A;  1J7E A;  2VUE A;  1E7B A;  2VUF A;  5IFO A;  5HOZ A;  1E7E A;  2BXD A;  4S1Y A;  4IW1 A;  5IIX A;  1HK5 A;  2BXH A;  5IJ5 A;  3B9M A;  4L9K A;  5IJE A;  2I2Z A;  4K71 A;  2BXE A;  3CX9 A;  4G04 A;  4N0F D;  4OR0 A;  1E7H A;  1E7A A;  4Z69 A;  4LB2 A;  1H9Z A; 
#chains in the Genus database with same CATH topology
 2GUT A;  5D7G A;  4TQ1 A;  2QMC A;  1HK3 A;  4BKE A;  3H37 A;  3ECP A;  3KIK A;  3A75 A;  4ZC6 A;  3NMU A;  5DBY A;  2EFH A;  1BJ5 A;  2BXB A;  2BXL A;  4F5T A;  3V08 A;  1MIY A;  4OTT A;  1NT2 B;  4LA0 A;  1BKE A;  2XMO A;  2LXS A;  4M70 B;  4ZBK A;  3M99 C;  4GDX A;  5FUO A;  1JNB A;  1E7I A;  2JUH A;  5IIH A;  4ZBQ A;  3W1S A;  1O9X A;  3FWB C;  1LNS A;  3A73 A;  1IJG A;  2DBW A;  5B5T A;  1GNJ A;  3ICX A;  1E7F A;  1VZS A;  4ZBR A;  3BPJ A;  2LXT A;  5GIP A;  4E99 A;  4F5V A;  2QHB A;  4HGM B;  1KXP D;  4FIP B;  3PLA A;  3KJL A;  2XVQ A;  1FOU A;  2YDF A;  2KBZ A;  4MBE C;  5IJF A;  1MIV A;  3LU8 A;  3B9L A;  4K2C A;  4W4U B;  3JQZ A;  3H3A A;  4OTU A;  3V09 A;  1KDX A;  4GG2 A;  2CKX A;  2BX8 A;  1MIW A;  1H5W A;  2XVU A;  5GHK A;  4GDK B;  3UIV A;  1E78 A;  3SIU B;  4PO0 A;  2XW0 A;  4N0U D;  3NVK A;  2DBX A;  1GNI A;  1BM0 A;  5GIO A;  2LQI A;  1N5U A;  4HGK A;  4JK4 A;  2LQH A;  1HA2 A;  1MA9 A;  2AGH B;  1HK4 A;  3G9K D;  2BXF A;  2VDB A;  5BPK A;  4L8U A;  3WHR A;  4ZCG A;  4DM0 A;  4F5S A;  2BXM A;  2BXQ A;  2XW1 A;  2EFE A;  5GIN A;  4Z9O A;  4C31 B;  2I30 A;  2K0N A;  3LU7 A;  3NVM A;  2BXA A;  4N3Z A;  2XVW A;  2XSI A;  2OZB B;  3WHS A;  4EMX A;  1LOT A;  1E7G A;  1TF0 A;  4GDL B;  3V03 A;  4IW2 A;  2ROH A;  3FWC C;  3SQJ A;  1KW2 A;  2BXK A;  2DBU A;  2Z8K A;  2BXC A;  3GQX A;  2E0Y A;  4FJC B;  2XVV A;  5DQF A;  3JRY A;  1HK1 A;  3LU6 A;  1AO6 A;  1MUS A;  3GQU A;  4NAW B;  2BXP A;  2BXO A;  5ID7 A;  2BXI A;  4G03 A;  2BXG A;  1HK2 A;  4LUF A;  1MM8 A;  4BY9 C;  2E0X A;  4L9Q A;  4OT2 A;  1J78 A;  1UOR A;  4J2V A;  1E7C A;  3MHS B;  3SIV B;  3FNM A;  4LB9 A;  4LUH A;  2Z8I A;  4I9O A;  3VQI A;  2LOQ A;  2KWF A;  5IIU A;  3TDL A;  4FK5 B;  4F5U A;  5ID9 A;  2V36 A;  2BXN A;  1J7E A;  2VUE A;  1E7B A;  2VUF A;  5IFO A;  5HOZ A;  3GA9 L;  2Z8J A;  4WA6 B;  2NQO A;  1E7E A;  2BXD A;  2DYM A;  2EFD A;  4G01 A;  4IW1 A;  4S1Y A;  3MHH B;  1HK5 A;  5IIX A;  2QM6 A;  2AJE A;  2BXH A;  5IJ5 A;  1VFI A;  2NNW A;  3B9M A;  4DHX B;  4L9K A;  5IJE A;  3WHQ A;  4D7X A;  2I2Z A;  4TQ0 A;  4K71 A;  2BXE A;  3CX9 A;  4G04 A;  2DG5 A;  1SB0 A;  1TXU A;  2EFC A;  1MUH A;  4N0F D;  4OR0 A;  1E7H A;  4ZUX V;  1E7A A;  2OT3 A;  2DYO A;  3NVI A;  4Z69 A;  4LB2 A;  1H9Z A; 
#chains in the Genus database with same CATH homology
 5D7G A;  4TQ1 A;  2QMC A;  1HK3 A;  4BKE A;  3H37 A;  3KIK A;  3A75 A;  4ZC6 A;  3NMU A;  5DBY A;  2EFH A;  1BJ5 A;  2BXB A;  2BXL A;  4F5T A;  3V08 A;  1MIY A;  4OTT A;  1NT2 B;  4LA0 A;  1BKE A;  2XMO A;  4ZBK A;  4M70 B;  3M99 C;  4GDX A;  5FUO A;  1JNB A;  1E7I A;  2JUH A;  5IIH A;  4ZBQ A;  3W1S A;  1O9X A;  3FWB C;  1LNS A;  3A73 A;  1IJG A;  2DBW A;  5B5T A;  1GNJ A;  3ICX A;  1E7F A;  1VZS A;  4ZBR A;  5GIP A;  4E99 A;  4F5V A;  2QHB A;  4HGM B;  1KXP D;  4FIP B;  3PLA A;  3KJL A;  2XVQ A;  1FOU A;  2YDF A;  2KBZ A;  4MBE C;  5IJF A;  1MIV A;  3LU8 A;  3B9L A;  4K2C A;  4W4U B;  3JQZ A;  3H3A A;  4OTU A;  3V09 A;  4GG2 A;  2CKX A;  2BX8 A;  1MIW A;  1H5W A;  2XVU A;  5GHK A;  4GDK B;  3UIV A;  1E78 A;  3SIU B;  4PO0 A;  2XW0 A;  4N0U D;  3NVK A;  2DBX A;  1GNI A;  1BM0 A;  5GIO A;  1N5U A;  4HGK A;  4JK4 A;  1HA2 A;  1MA9 A;  3G9K D;  1HK4 A;  5BPK A;  2BXF A;  2VDB A;  4L8U A;  3WHR A;  4ZCG A;  4F5S A;  2BXM A;  2BXQ A;  2XW1 A;  2EFE A;  5GIN A;  4Z9O A;  4C31 B;  2I30 A;  3LU7 A;  3NVM A;  2BXA A;  4N3Z A;  2XVW A;  2XSI A;  2OZB B;  3WHS A;  4EMX A;  1LOT A;  1E7G A;  1TF0 A;  4GDL B;  3V03 A;  4IW2 A;  2ROH A;  3FWC C;  3SQJ A;  1KW2 A;  2BXK A;  2DBU A;  2Z8K A;  2BXC A;  3GQX A;  2E0Y A;  4FJC B;  2XVV A;  5DQF A;  3JRY A;  1HK1 A;  3LU6 A;  1AO6 A;  3GQU A;  4NAW B;  2BXP A;  2BXO A;  5ID7 A;  2BXI A;  4G03 A;  2BXG A;  1HK2 A;  4LUF A;  4BY9 C;  2E0X A;  4L9Q A;  4OT2 A;  1J78 A;  1UOR A;  4J2V A;  1E7C A;  3MHS B;  3SIV B;  3FNM A;  4LB9 A;  4LUH A;  2Z8I A;  3VQI A;  5IIU A;  2LOQ A;  3TDL A;  4FK5 B;  4F5U A;  5ID9 A;  2V36 A;  2BXN A;  1J7E A;  2VUE A;  1E7B A;  2VUF A;  5IFO A;  5HOZ A;  3GA9 L;  2Z8J A;  4WA6 B;  2NQO A;  1E7E A;  2BXD A;  2DYM A;  2EFD A;  4G01 A;  4IW1 A;  4S1Y A;  3MHH B;  1HK5 A;  5IIX A;  2QM6 A;  2AJE A;  2BXH A;  5IJ5 A;  1VFI A;  2NNW A;  3B9M A;  4DHX B;  4L9K A;  5IJE A;  3WHQ A;  2I2Z A;  4TQ0 A;  4K71 A;  2BXE A;  3CX9 A;  4G04 A;  2DG5 A;  1TXU A;  2EFC A;  4N0F D;  4OR0 A;  1E7H A;  4ZUX V;  1E7A A;  2OT3 A;  2DYO A;  3NVI A;  4Z69 A;  4LB2 A;  1H9Z A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...