2BXIA

Human serum albumin complexed with myristate and azapropazone
Total Genus 218
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
218
sequence length
582
structure length
582
Chain Sequence
HKSEVAHRFKDLGEENFKALVLIAFAQYLQQCPFEDHVKLVNEVTEFAKTCVADESAENCDKSLHTLFGDKLCTVATLRETYGEMADCCAKQEPERNECFLQHKDDNPNLPRLVRPEVDVMCTAFHDNEETFLKKYLYEIARRHPYFYAPELLFFAKRYKAAFTECCQAADKAACLLPKLDELRDEGKASSAKQRLKCASLQKFGERAFKAWAVARLSQRFPKAEFAEVSKLVTDLTKVHTECCHGDLLECADDRADLAKYICENQDSISSKLKECCEKPLLEKSHCIAEVENDEMPADLPSLAADFVESKDVCKNYAEAKDVFLGMFLYEYARRHPDYSVVLLLRLAKTYETTLEKCCAAADPHECYAKVFDEFKPLVEEPQNLIKQNCELFEQLGEYKFQNALLVRYTKKVPQVSTPTLVEVSRNLGKVGSKCCKHPEAKRMPCAEDYLSVVLNQLCVLHEKTPVSDRVTKCCTESLVNRRPCFSALEVDETYVPKEFNAETFTFHADICTLSEKEEQIKKQTALVELVKHKPKATKEQLKAVMDDFAAFVEKCCKADDKETCFAEEGKKLVAASQAALG
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords SERUM ALBUMIN
publication title Structural Basis of the Drug-Binding Specificity of Human Serum Albumin.
pubmed doi rcsb
source organism Homo sapiens
molecule tags Transport protein
total genus 218
structure length 582
sequence length 582
ec nomenclature
pdb deposition date 2005-07-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00273 Serum_albumin Serum albumin family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 2bxiA03
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 2bxiA02
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 2bxiA04
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 2bxiA01
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 2bxiA06
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 2bxiA05
1J7EA 3LU8A 1KW2A 1BKEA 5DBYA 3V03A 3V09A 1MA9A 2XSIA 4L8UA 4LA0A 1BM0A 1E7AA 4N0FD 2XVQA 4HGKA 3JQZA 3UIVA 2BXNA 2BXFA 4E99A 2BXIA 4S1YA 5IIXA 4OR0A 1E78A 1UORA 2BXDA 3LU7A 3TDLA 2BXOA 1E7GA 4F5TA 4N0UD 4L9KA 1H9ZA 4G03A 2I30A 2YDFA 1BJ5A 4IW1A 5IJEA 4JK4A 5HOZA 3B9MA 1GNJA 1GNIA 1N5UA 4IW2A 2VUEA 4K71A 2BXPA 5DQFA 2BX8A 2I2ZA 3JRYA 2BXAA 5ID9A 4F5UA 5IJFA 5FUOA 2XW0A 4OT2A 4ZBQA 3SQJA 2VUFA 4BKEA 1E7IA 4Z69A 2XVVA 4LUFA 4LB2A 4L9QA 4LB9A 1HK5A 2BXGA 5IIHA 2XVUA 1HK1A 2XW1A 1HK3A 2BXLA 3B9LA 1E7BA 1HK4A 2BXBA 2VDBA 4ZBRA 1E7FA 4EMXA 2BXMA 3A73A 2BXCA 2BXHA 1HK2A 5IFOA 4F5VA 4LUHA 2BXEA 2BXKA 1E7HA 4G04A 4K2CA 1E7EA 4PO0A 1J78A 4HGMB 1O9XA 5IJ5A 3V08A 4J2VA 5IIUA 1HA2A 5ID7A 1LOTA 1E7CA 3LU6A 1TF0A 1AO6A 4F5SA 3CX9A 5GHKA 2BXQA 2XVWA 1KXPD
chains in the Genus database with same CATH superfamily
2NNWA 3FWBC 1J7EA 2EFEA 1MIYA 3LU8A 4GG2A 3NVIA 2Z8IA 2XMOA 1KW2A 1BKEA 5DBYA 3V03A 3M99C 3V09A 2JUHA 1MA9A 2XSIA 4L8UA 4LA0A 1BM0A 2AGHB 2EFHA 1E7AA 3WHSA 4N0FD 2XVQA 2NQOA 2DBWA 4HGKA 3JQZA 4TQ0A 2LQHA 3UIVA 3W1SA 1NT2B 2BXNA 3BPJA 2BXFA 2DYOA 2KBZA 3KJLA 1MIWA 2Z8KA 2BXIA 4MBEC 4E99A 3NMUA 3MHHB 4S1YA 2DG5A 5IIXA 4OR0A 2LXTA 1E78A 1UORA 2BXDA 3LU7A 4GDLB 3TDLA 4W4UB 2CKXA 2DBUA 2BXOA 1E7GA 4D7XA 4F5TA 4N0UD 4L9KA 4Z9OA 1H9ZA 4G03A 3GQUA 2LOQA 2I30A 2YDFA 1BJ5A 4IW1A 5IJEA 4JK4A 5HOZA 3B9MA 1GNJA 1GNIA 3GQXA 4DM0A 4ZUXV 1N5UA 2VUEA 4IW2A 4K71A 4I9OA 4TQ1A 2BXPA 5DQFA 1SB0A 2BX8A 1MUSA 2KWFA 4NAWB 2I2ZA 3JRYA 2BXAA 5ID9A 4WA6B 4F5UA 5GIOA 5IJFA 5FUOA 2AJEA 2DBXA 4OTUA 2LXSA 2Z8JA 2XW0A 4OT2A 4ZBQA 5BPKA 3SQJA 1VFIA 2VUFA 3KIKA 2EFDA 4BKEA 1E7IA 2K0NA 4Z69A 2ROHA 2XVVA 4LUFA 4LB2A 4L9QA 1MM8A 4LB9A 4M70B 1HK5A 2BXGA 3G9KD 3SIUB 5IIHA 2XVUA 1HK1A 2XW1A 1HK3A 3ECPA 2BXLA 3B9LA 1E7BA 1VZSA 3NVMA 4DHXB 1LNSA 4FIPB 1HK4A 2BXBA 4G01A 5GIPA 4FJCB 2E0XA 2VDBA 4ZBRA 4ZCGA 3SIVB 1E7FA 1TXUA 4ZC6A 2BXMA 3A73A 1MIVA 4OTTA 4EMXA 3WHRA 3NVKA 2BXCA 2BXHA 4FK5B 1HK2A 5IFOA 4C31B 3A75A 4F5VA 4BY9C 2E0YA 1FOUA 1JNBA 4LUHA 2QHBA 2BXEA 2OT3A 2BXKA 3PLAA 1E7HA 2QM6A 3ICXA 4G04A 5GINA 4K2CA 1E7EA 3GA9L 4PO0A 3MHSB 1J78A 4HGMB 2GUTA 3VQIA 1O9XA 5IJ5A 2QMCA 3V08A 5B5TA 2DYMA 3WHQA 1H5WA 4GDXA 4J2VA 4GDKB 5IIUA 1HA2A 5ID7A 1LOTA 3FWCC 1KDXA 1E7CA 3LU6A 4N3ZA 1TF0A 2OZBB 4ZBKA 1AO6A 2LQIA 4F5SA 1MUHA 1IJGA 2EFCA 3CX9A 5D7GA 5GHKA 2BXQA 2XVWA 3H3AA 1KXPD 3H37A 3FNMA 2V36A
chains in the Genus database with same CATH topology
2NNWA 3FWBC 1J7EA 2EFEA 1MIYA 3LU8A 4GG2A 3NVIA 2Z8IA 2XMOA 1KW2A 1BKEA 5DBYA 3V03A 3M99C 3V09A 2JUHA 1MA9A 2XSIA 4L8UA 4LA0A 1BM0A 2EFHA 1E7AA 3WHSA 4N0FD 2XVQA 2NQOA 2DBWA 4HGKA 3JQZA 4TQ0A 3UIVA 3W1SA 1NT2B 2BXNA 2BXFA 2DYOA 2KBZA 3KJLA 1MIWA 2Z8KA 2BXIA 4MBEC 4E99A 3NMUA 3MHHB 4S1YA 2DG5A 5IIXA 4OR0A 1E78A 1UORA 2BXDA 3LU7A 4GDLB 3TDLA 4W4UB 2CKXA 2DBUA 2BXOA 1E7GA 4F5TA 4N0UD 4L9KA 4Z9OA 1H9ZA 4G03A 3GQUA 2LOQA 2I30A 2YDFA 1BJ5A 4IW1A 5IJEA 4JK4A 5HOZA 3B9MA 1GNJA 1GNIA 3GQXA 4ZUXV 1N5UA 2VUEA 4IW2A 4K71A 4TQ1A 2BXPA 5DQFA 2BX8A 4NAWB 2I2ZA 3JRYA 2BXAA 5ID9A 4WA6B 4F5UA 5GIOA 5IJFA 5FUOA 2AJEA 2DBXA 4OTUA 2Z8JA 2XW0A 4OT2A 4ZBQA 5BPKA 3SQJA 1VFIA 2VUFA 3KIKA 2EFDA 4BKEA 1E7IA 4Z69A 2ROHA 2XVVA 4LUFA 4LB2A 4L9QA 4LB9A 4M70B 1HK5A 2BXGA 3G9KD 3SIUB 5IIHA 2XVUA 1HK1A 2XW1A 1HK3A 2BXLA 3B9LA 1E7BA 1VZSA 3NVMA 4DHXB 1LNSA 4FIPB 1HK4A 2BXBA 4G01A 5GIPA 4FJCB 2E0XA 2VDBA 4ZBRA 4ZCGA 3SIVB 1E7FA 1TXUA 4ZC6A 2BXMA 3A73A 1MIVA 4OTTA 4EMXA 3WHRA 3NVKA 2BXCA 2BXHA 4FK5B 1HK2A 5IFOA 4C31B 3A75A 4F5VA 4BY9C 2E0YA 1FOUA 1JNBA 4LUHA 2QHBA 2BXEA 2OT3A 2BXKA 3PLAA 1E7HA 2QM6A 3ICXA 4G04A 5GINA 4K2CA 1E7EA 3GA9L 4PO0A 3MHSB 1J78A 4HGMB 3VQIA 1O9XA 5IJ5A 2QMCA 3V08A 5B5TA 2DYMA 3WHQA 1H5WA 4GDXA 4J2VA 4GDKB 5IIUA 1HA2A 5ID7A 1LOTA 3FWCC 1E7CA 3LU6A 4N3ZA 1TF0A 2OZBB 4ZBKA 1AO6A 4F5SA 1IJGA 2EFCA 3CX9A 5D7GA 5GHKA 2BXQA 2XVWA 3H3AA 1KXPD 3H37A 3FNMA 2V36A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1J7E A;  3LU8 A;  1KW2 A;  1BKE A;  5DBY A;  3V03 A;  3V09 A;  1MA9 A;  2XSI A;  4L8U A;  4LA0 A;  1BM0 A;  1E7A A;  4N0F D;  2XVQ A;  4HGK A;  3JQZ A;  3UIV A;  2BXN A;  2BXF A;  4E99 A;  2BXI A;  4S1Y A;  5IIX A;  4OR0 A;  1E78 A;  1UOR A;  2BXD A;  3LU7 A;  3TDL A;  2BXO A;  1E7G A;  4F5T A;  4N0U D;  4L9K A;  1H9Z A;  4G03 A;  2I30 A;  2YDF A;  1BJ5 A;  4IW1 A;  5IJE A;  4JK4 A;  5HOZ A;  3B9M A;  1GNJ A;  1GNI A;  1N5U A;  4IW2 A;  2VUE A;  4K71 A;  2BXP A;  5DQF A;  2BX8 A;  2I2Z A;  3JRY A;  2BXA A;  5ID9 A;  4F5U A;  5IJF A;  5FUO A;  2XW0 A;  4OT2 A;  4ZBQ A;  3SQJ A;  2VUF A;  4BKE A;  1E7I A;  4Z69 A;  2XVV A;  4LUF A;  4LB2 A;  4L9Q A;  4LB9 A;  1HK5 A;  2BXG A;  5IIH A;  2XVU A;  1HK1 A;  2XW1 A;  1HK3 A;  2BXL A;  3B9L A;  1E7B A;  1HK4 A;  2BXB A;  2VDB A;  4ZBR A;  1E7F A;  4EMX A;  2BXM A;  3A73 A;  2BXC A;  2BXH A;  1HK2 A;  5IFO A;  4F5V A;  4LUH A;  2BXE A;  2BXK A;  1E7H A;  4G04 A;  4K2C A;  1E7E A;  4PO0 A;  1J78 A;  4HGM B;  1O9X A;  5IJ5 A;  3V08 A;  4J2V A;  5IIU A;  1HA2 A;  5ID7 A;  1LOT A;  1E7C A;  3LU6 A;  1TF0 A;  1AO6 A;  4F5S A;  3CX9 A;  5GHK A;  2BXQ A;  2XVW A;  1KXP D; 
#chains in the Genus database with same CATH topology
 2NNW A;  3FWB C;  1J7E A;  2EFE A;  1MIY A;  3LU8 A;  4GG2 A;  3NVI A;  2Z8I A;  2XMO A;  1KW2 A;  1BKE A;  5DBY A;  3V03 A;  3M99 C;  3V09 A;  2JUH A;  1MA9 A;  2XSI A;  4L8U A;  4LA0 A;  1BM0 A;  2AGH B;  2EFH A;  1E7A A;  3WHS A;  4N0F D;  2XVQ A;  2NQO A;  2DBW A;  4HGK A;  3JQZ A;  4TQ0 A;  2LQH A;  3UIV A;  3W1S A;  1NT2 B;  2BXN A;  3BPJ A;  2BXF A;  2DYO A;  2KBZ A;  3KJL A;  1MIW A;  2Z8K A;  2BXI A;  4MBE C;  4E99 A;  3NMU A;  3MHH B;  4S1Y A;  2DG5 A;  5IIX A;  4OR0 A;  2LXT A;  1E78 A;  1UOR A;  2BXD A;  3LU7 A;  4GDL B;  3TDL A;  4W4U B;  2CKX A;  2DBU A;  2BXO A;  1E7G A;  4D7X A;  4F5T A;  4N0U D;  4L9K A;  4Z9O A;  1H9Z A;  4G03 A;  3GQU A;  2LOQ A;  2I30 A;  2YDF A;  1BJ5 A;  4IW1 A;  5IJE A;  4JK4 A;  5HOZ A;  3B9M A;  1GNJ A;  1GNI A;  3GQX A;  4DM0 A;  4ZUX V;  1N5U A;  2VUE A;  4IW2 A;  4K71 A;  4I9O A;  4TQ1 A;  2BXP A;  5DQF A;  1SB0 A;  2BX8 A;  1MUS A;  2KWF A;  4NAW B;  2I2Z A;  3JRY A;  2BXA A;  5ID9 A;  4WA6 B;  4F5U A;  5GIO A;  5IJF A;  5FUO A;  2AJE A;  2DBX A;  4OTU A;  2LXS A;  2Z8J A;  2XW0 A;  4OT2 A;  4ZBQ A;  5BPK A;  3SQJ A;  1VFI A;  2VUF A;  3KIK A;  2EFD A;  4BKE A;  1E7I A;  2K0N A;  4Z69 A;  2ROH A;  2XVV A;  4LUF A;  4LB2 A;  4L9Q A;  1MM8 A;  4LB9 A;  4M70 B;  1HK5 A;  2BXG A;  3G9K D;  3SIU B;  5IIH A;  2XVU A;  1HK1 A;  2XW1 A;  1HK3 A;  3ECP A;  2BXL A;  3B9L A;  1E7B A;  1VZS A;  3NVM A;  4DHX B;  1LNS A;  4FIP B;  1HK4 A;  2BXB A;  4G01 A;  5GIP A;  4FJC B;  2E0X A;  2VDB A;  4ZBR A;  4ZCG A;  3SIV B;  1E7F A;  1TXU A;  4ZC6 A;  2BXM A;  3A73 A;  1MIV A;  4OTT A;  4EMX A;  3WHR A;  3NVK A;  2BXC A;  2BXH A;  4FK5 B;  1HK2 A;  5IFO A;  4C31 B;  3A75 A;  4F5V A;  4BY9 C;  2E0Y A;  1FOU A;  1JNB A;  4LUH A;  2QHB A;  2BXE A;  2OT3 A;  2BXK A;  3PLA A;  1E7H A;  2QM6 A;  3ICX A;  4G04 A;  5GIN A;  4K2C A;  1E7E A;  3GA9 L;  4PO0 A;  3MHS B;  1J78 A;  4HGM B;  2GUT A;  3VQI A;  1O9X A;  5IJ5 A;  2QMC A;  3V08 A;  5B5T A;  2DYM A;  3WHQ A;  1H5W A;  4GDX A;  4J2V A;  4GDK B;  5IIU A;  1HA2 A;  5ID7 A;  1LOT A;  3FWC C;  1KDX A;  1E7C A;  3LU6 A;  4N3Z A;  1TF0 A;  2OZB B;  4ZBK A;  1AO6 A;  2LQI A;  4F5S A;  1MUH A;  1IJG A;  2EFC A;  3CX9 A;  5D7G A;  5GHK A;  2BXQ A;  2XVW A;  3H3A A;  1KXP D;  3H37 A;  3FNM A;  2V36 A; 
#chains in the Genus database with same CATH homology
 2NNW A;  3FWB C;  1J7E A;  2EFE A;  1MIY A;  3LU8 A;  4GG2 A;  3NVI A;  2Z8I A;  2XMO A;  1KW2 A;  1BKE A;  5DBY A;  3V03 A;  3M99 C;  3V09 A;  2JUH A;  1MA9 A;  2XSI A;  4L8U A;  4LA0 A;  1BM0 A;  2EFH A;  1E7A A;  3WHS A;  4N0F D;  2XVQ A;  2NQO A;  2DBW A;  4HGK A;  3JQZ A;  4TQ0 A;  3UIV A;  3W1S A;  1NT2 B;  2BXN A;  2BXF A;  2DYO A;  2KBZ A;  3KJL A;  1MIW A;  2Z8K A;  2BXI A;  4MBE C;  4E99 A;  3NMU A;  3MHH B;  4S1Y A;  2DG5 A;  5IIX A;  4OR0 A;  1E78 A;  1UOR A;  2BXD A;  3LU7 A;  4GDL B;  3TDL A;  4W4U B;  2CKX A;  2DBU A;  2BXO A;  1E7G A;  4F5T A;  4N0U D;  4L9K A;  4Z9O A;  1H9Z A;  4G03 A;  3GQU A;  2LOQ A;  2I30 A;  2YDF A;  1BJ5 A;  4IW1 A;  5IJE A;  4JK4 A;  5HOZ A;  3B9M A;  1GNJ A;  1GNI A;  3GQX A;  4ZUX V;  1N5U A;  2VUE A;  4IW2 A;  4K71 A;  4TQ1 A;  2BXP A;  5DQF A;  2BX8 A;  4NAW B;  2I2Z A;  3JRY A;  2BXA A;  5ID9 A;  4WA6 B;  4F5U A;  5GIO A;  5IJF A;  5FUO A;  2AJE A;  2DBX A;  4OTU A;  2Z8J A;  2XW0 A;  4OT2 A;  4ZBQ A;  5BPK A;  3SQJ A;  1VFI A;  2VUF A;  3KIK A;  2EFD A;  4BKE A;  1E7I A;  4Z69 A;  2ROH A;  2XVV A;  4LUF A;  4LB2 A;  4L9Q A;  4LB9 A;  4M70 B;  1HK5 A;  2BXG A;  3G9K D;  3SIU B;  5IIH A;  2XVU A;  1HK1 A;  2XW1 A;  1HK3 A;  2BXL A;  3B9L A;  1E7B A;  1VZS A;  3NVM A;  4DHX B;  1LNS A;  4FIP B;  1HK4 A;  2BXB A;  4G01 A;  5GIP A;  4FJC B;  2E0X A;  2VDB A;  4ZBR A;  4ZCG A;  3SIV B;  1E7F A;  1TXU A;  4ZC6 A;  2BXM A;  3A73 A;  1MIV A;  4OTT A;  4EMX A;  3WHR A;  3NVK A;  2BXC A;  2BXH A;  4FK5 B;  1HK2 A;  5IFO A;  4C31 B;  3A75 A;  4F5V A;  4BY9 C;  2E0Y A;  1FOU A;  1JNB A;  4LUH A;  2QHB A;  2BXE A;  2OT3 A;  2BXK A;  3PLA A;  1E7H A;  2QM6 A;  3ICX A;  4G04 A;  5GIN A;  4K2C A;  1E7E A;  3GA9 L;  4PO0 A;  3MHS B;  1J78 A;  4HGM B;  3VQI A;  1O9X A;  5IJ5 A;  2QMC A;  3V08 A;  5B5T A;  2DYM A;  3WHQ A;  1H5W A;  4GDX A;  4J2V A;  4GDK B;  5IIU A;  1HA2 A;  5ID7 A;  1LOT A;  3FWC C;  1E7C A;  3LU6 A;  4N3Z A;  1TF0 A;  2OZB B;  4ZBK A;  1AO6 A;  4F5S A;  1IJG A;  2EFC A;  3CX9 A;  5D7G A;  5GHK A;  2BXQ A;  2XVW A;  3H3A A;  1KXP D;  3H37 A;  3FNM A;  2V36 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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