2BXIA

Human serum albumin complexed with myristate and azapropazone
Total Genus 218
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
218
sequence length
582
structure length
582
Chain Sequence
HKSEVAHRFKDLGEENFKALVLIAFAQYLQQCPFEDHVKLVNEVTEFAKTCVADESAENCDKSLHTLFGDKLCTVATLRETYGEMADCCAKQEPERNECFLQHKDDNPNLPRLVRPEVDVMCTAFHDNEETFLKKYLYEIARRHPYFYAPELLFFAKRYKAAFTECCQAADKAACLLPKLDELRDEGKASSAKQRLKCASLQKFGERAFKAWAVARLSQRFPKAEFAEVSKLVTDLTKVHTECCHGDLLECADDRADLAKYICENQDSISSKLKECCEKPLLEKSHCIAEVENDEMPADLPSLAADFVESKDVCKNYAEAKDVFLGMFLYEYARRHPDYSVVLLLRLAKTYETTLEKCCAAADPHECYAKVFDEFKPLVEEPQNLIKQNCELFEQLGEYKFQNALLVRYTKKVPQVSTPTLVEVSRNLGKVGSKCCKHPEAKRMPCAEDYLSVVLNQLCVLHEKTPVSDRVTKCCTESLVNRRPCFSALEVDETYVPKEFNAETFTFHADICTLSEKEEQIKKQTALVELVKHKPKATKEQLKAVMDDFAAFVEKCCKADDKETCFAEEGKKLVAASQAALG
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title Structural Basis of the Drug-Binding Specificity of Human Serum Albumin.
pubmed doi rcsb
molecule keywords SERUM ALBUMIN
molecule tags Transport protein
source organism Homo sapiens
total genus 218
structure length 582
sequence length 582
ec nomenclature
pdb deposition date 2005-07-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00273 Serum_albumin Serum albumin family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 2bxiA03
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 2bxiA02
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 2bxiA04
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 2bxiA01
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 2bxiA06
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 2bxiA05
3LU6A 2BXBA 4HGKA 4L9QA 5IIHA 1AO6A 2BXHA 3LU8A 1E7IA 1H9ZA 2VUFA 2XSIA 4G04A 4LB9A 3JRYA 4HGMB 2XW1A 1E7BA 4ZBRA 1E7FA 2BXOA 4ZBQA 4IW2A 1E7EA 2BXMA 4F5TA 1GNIA 5GHKA 3V03A 1HK2A 1KW2A 5IJEA 2BXQA 5ID7A 4S1YA 2BXGA 3JQZA 2BXKA 4LB2A 3B9LA 4F5SA 2XVQA 1BM0A 2XVWA 1HK1A 5DQFA 1HK5A 4OT2A 3UIVA 4N0UD 2YDFA 4OR0A 2BXIA 4IW1A 1E7HA 4Z69A 2BXCA 2I30A 3SQJA 2BXPA 4LA0A 1E7CA 5IFOA 5IIXA 5IJFA 4K2CA 4L8UA 1J7EA 4G03A 5FUOA 1KXPD 3B9MA 5IIUA 2BXEA 4J2VA 4JK4A 1N5UA 2BXLA 2VUEA 1E7GA 2XVUA 5HOZA 4PO0A 3TDLA 2BXNA 1LOTA 5DBYA 1HK3A 4F5VA 2BXAA 4L9KA 3CX9A 1E78A 1BKEA 4LUFA 4K71A 1J78A 2BX8A 4BKEA 1HA2A 1TF0A 1E7AA 3V09A 3LU7A 2BXFA 3A73A 4E99A 2VDBA 4LUHA 1HK4A 2BXDA 4N0FD 1BJ5A 4F5UA 1GNJA 4EMXA 2XW0A 5ID9A 3V08A 1UORA 2I2ZA 1O9XA 2XVVA 1MA9A 5IJ5A
chains in the Genus database with same CATH superfamily
3LU6A 2K0NA 4ZCGA 2QM6A 3NVKA 2BXBA 4HGKA 3WHQA 4L9QA 5IIHA 1AO6A 2BXHA 3LU8A 1E7IA 1H9ZA 2VUFA 2XSIA 4G04A 1MUSA 4LB9A 3JRYA 1H5WA 4DM0A 4HGMB 2XW1A 1E7BA 3G9KD 4ZBRA 1VFIA 1E7FA 1FOUA 2AGHB 2BXOA 2LOQA 4IW2A 1E7EA 4ZBQA 4FIPB 2BXMA 4W4UB 4F5TA 1GNIA 3FWBC 3GQXA 5GHKA 1HK2A 1KW2A 2E0YA 2LXSA 4FJCB 4GDXA 1LNSA 3V03A 5BPKA 5IJEA 2LQHA 2BXQA 4FK5B 5B5TA 5ID7A 4TQ1A 2DYMA 2QMCA 4S1YA 1TXUA 2BXGA 3A75A 3SIVB 1MIWA 2DYOA 3KIKA 3PLAA 3JQZA 4GDLB 2BXKA 2EFHA 4LB2A 3B9LA 3ECPA 4D7XA 4I9OA 4F5SA 2DBUA 3MHSB 2XVQA 1BM0A 2XVWA 1HK1A 5DQFA 1HK5A 4OT2A 3MHHB 3FWCC 3UIVA 4N0UD 4NAWB 3W1SA 2YDFA 3WHRA 1MM8A 4OR0A 2BXIA 4IW1A 2JUHA 1E7HA 3VQIA 4Z69A 2BXCA 2I30A 4M70B 3SQJA 2BXPA 3H3AA 2DBXA 4LA0A 1MUHA 1E7CA 2XMOA 5IFOA 2Z8IA 5IIXA 1NT2B 2QHBA 5IJFA 2LXTA 4K2CA 4WA6B 4L8UA 1J7EA 2EFCA 4G03A 2EFDA 5FUOA 2DBWA 1KXPD 3B9MA 5IIUA 2BXEA 2NNWA 2LQIA 4J2VA 4GDKB 4JK4A 1MIVA 4GG2A 2CKXA 2DG5A 3NVIA 1MIYA 1N5UA 2BXLA 2VUEA 1E7GA 2XVUA 5HOZA 2OZBB 4OTTA 4PO0A 2OT3A 3NVMA 3TDLA 2ROHA 2BXNA 1LOTA 5DBYA 2V36A 3BPJA 1HK3A 4F5VA 2BXAA 2KWFA 3ICXA 4L9KA 4TQ0A 2AJEA 3CX9A 1E78A 4OTUA 1BKEA 4LUFA 4K71A 1J78A 3WHSA 3M99C 2BX8A 3SIUB 3GQUA 4BKEA 4G01A 5D7GA 1HA2A 1TF0A 2Z8JA 2GUTA 4ZBKA 1E7AA 4ZC6A 3V09A 5GIPA 3LU7A 3NMUA 1SB0A 2BXFA 3A73A 4E99A 5GINA 2VDBA 4LUHA 5GIOA 1HK4A 4DHXB 2BXDA 4Z9OA 2EFEA 2NQOA 2KBZA 4N0FD 1JNBA 1BJ5A 3KJLA 1IJGA 4F5UA 1GNJA 4EMXA 1KDXA 4C31B 3GA9L 1VZSA 2XW0A 5ID9A 3V08A 1UORA 3H37A 2I2ZA 4MBEC 4BY9C 4ZUXV 2Z8KA 1O9XA 2XVVA 4N3ZA 3FNMA 2E0XA 1MA9A 5IJ5A
chains in the Genus database with same CATH topology
3LU6A 4ZCGA 2QM6A 3NVKA 2BXBA 4HGKA 3WHQA 4L9QA 5IIHA 1AO6A 2BXHA 3LU8A 1E7IA 1H9ZA 2VUFA 2XSIA 4G04A 4LB9A 3JRYA 1H5WA 4HGMB 2XW1A 1E7BA 3G9KD 4ZBRA 1VFIA 1E7FA 1FOUA 2BXOA 2LOQA 4IW2A 4ZBQA 1E7EA 4FIPB 2BXMA 4W4UB 4F5TA 1GNIA 3FWBC 3GQXA 5GHKA 1HK2A 1KW2A 2E0YA 4FJCB 4GDXA 3V03A 1LNSA 5BPKA 5IJEA 2BXQA 4FK5B 5B5TA 5ID7A 4TQ1A 2DYMA 2QMCA 4S1YA 1TXUA 2BXGA 3A75A 3SIVB 1MIWA 2DYOA 3KIKA 3PLAA 3JQZA 4GDLB 2BXKA 2EFHA 4LB2A 3B9LA 4F5SA 2DBUA 3MHSB 2XVQA 1BM0A 2XVWA 1HK1A 5DQFA 1HK5A 4OT2A 3MHHB 3FWCC 3UIVA 4N0UD 4NAWB 3W1SA 2YDFA 3WHRA 4OR0A 2BXIA 4IW1A 2JUHA 1E7HA 3VQIA 4Z69A 2BXCA 2I30A 4M70B 3SQJA 2BXPA 3H3AA 2DBXA 4LA0A 1E7CA 2XMOA 5IFOA 2Z8IA 5IIXA 1NT2B 2QHBA 5IJFA 4K2CA 4WA6B 4L8UA 1J7EA 2EFCA 4G03A 2EFDA 5FUOA 2DBWA 1KXPD 3B9MA 5IIUA 2BXEA 2NNWA 4J2VA 4GDKB 4JK4A 1MIVA 4GG2A 2CKXA 2DG5A 3NVIA 1MIYA 1N5UA 2BXLA 2VUEA 1E7GA 2XVUA 5HOZA 2OZBB 4OTTA 4PO0A 2OT3A 3NVMA 3TDLA 2ROHA 2BXNA 1LOTA 5DBYA 2V36A 1HK3A 4F5VA 2BXAA 3ICXA 4L9KA 4TQ0A 2AJEA 3CX9A 1E78A 4OTUA 1BKEA 4LUFA 4K71A 1J78A 3WHSA 3M99C 2BX8A 3SIUB 3GQUA 4BKEA 4G01A 5D7GA 1HA2A 1TF0A 2Z8JA 4ZBKA 1E7AA 4ZC6A 3V09A 5GIPA 3LU7A 3NMUA 2BXFA 3A73A 4E99A 5GINA 2VDBA 4LUHA 5GIOA 1HK4A 4DHXB 2BXDA 4Z9OA 2EFEA 2NQOA 2KBZA 4N0FD 1JNBA 1BJ5A 3KJLA 1IJGA 4F5UA 1GNJA 4EMXA 4C31B 3GA9L 1VZSA 2XW0A 5ID9A 3V08A 1UORA 3H37A 2I2ZA 4MBEC 4BY9C 4ZUXV 2Z8KA 1O9XA 2XVVA 4N3ZA 3FNMA 2E0XA 1MA9A 5IJ5A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3LU6 A;  2BXB A;  4HGK A;  4L9Q A;  5IIH A;  1AO6 A;  2BXH A;  3LU8 A;  1E7I A;  1H9Z A;  2VUF A;  2XSI A;  4G04 A;  4LB9 A;  3JRY A;  4HGM B;  2XW1 A;  1E7B A;  4ZBR A;  1E7F A;  2BXO A;  4ZBQ A;  4IW2 A;  1E7E A;  2BXM A;  4F5T A;  1GNI A;  5GHK A;  3V03 A;  1HK2 A;  1KW2 A;  5IJE A;  2BXQ A;  5ID7 A;  4S1Y A;  2BXG A;  3JQZ A;  2BXK A;  4LB2 A;  3B9L A;  4F5S A;  2XVQ A;  1BM0 A;  2XVW A;  1HK1 A;  5DQF A;  1HK5 A;  4OT2 A;  3UIV A;  4N0U D;  2YDF A;  4OR0 A;  2BXI A;  4IW1 A;  1E7H A;  4Z69 A;  2BXC A;  2I30 A;  3SQJ A;  2BXP A;  4LA0 A;  1E7C A;  5IFO A;  5IIX A;  5IJF A;  4K2C A;  4L8U A;  1J7E A;  4G03 A;  5FUO A;  1KXP D;  3B9M A;  5IIU A;  2BXE A;  4J2V A;  4JK4 A;  1N5U A;  2BXL A;  2VUE A;  1E7G A;  2XVU A;  5HOZ A;  4PO0 A;  3TDL A;  2BXN A;  1LOT A;  5DBY A;  1HK3 A;  4F5V A;  2BXA A;  4L9K A;  3CX9 A;  1E78 A;  1BKE A;  4LUF A;  4K71 A;  1J78 A;  2BX8 A;  4BKE A;  1HA2 A;  1TF0 A;  1E7A A;  3V09 A;  3LU7 A;  2BXF A;  3A73 A;  4E99 A;  2VDB A;  4LUH A;  1HK4 A;  2BXD A;  4N0F D;  1BJ5 A;  4F5U A;  1GNJ A;  4EMX A;  2XW0 A;  5ID9 A;  3V08 A;  1UOR A;  2I2Z A;  1O9X A;  2XVV A;  1MA9 A;  5IJ5 A; 
#chains in the Genus database with same CATH topology
 3LU6 A;  2K0N A;  4ZCG A;  2QM6 A;  3NVK A;  2BXB A;  4HGK A;  3WHQ A;  4L9Q A;  5IIH A;  1AO6 A;  2BXH A;  3LU8 A;  1E7I A;  1H9Z A;  2VUF A;  2XSI A;  4G04 A;  1MUS A;  4LB9 A;  3JRY A;  1H5W A;  4DM0 A;  4HGM B;  2XW1 A;  1E7B A;  3G9K D;  4ZBR A;  1VFI A;  1E7F A;  1FOU A;  2AGH B;  2BXO A;  2LOQ A;  4IW2 A;  1E7E A;  4ZBQ A;  4FIP B;  2BXM A;  4W4U B;  4F5T A;  1GNI A;  3FWB C;  3GQX A;  5GHK A;  1HK2 A;  1KW2 A;  2E0Y A;  2LXS A;  4FJC B;  4GDX A;  1LNS A;  3V03 A;  5BPK A;  5IJE A;  2LQH A;  2BXQ A;  4FK5 B;  5B5T A;  5ID7 A;  4TQ1 A;  2DYM A;  2QMC A;  4S1Y A;  1TXU A;  2BXG A;  3A75 A;  3SIV B;  1MIW A;  2DYO A;  3KIK A;  3PLA A;  3JQZ A;  4GDL B;  2BXK A;  2EFH A;  4LB2 A;  3B9L A;  3ECP A;  4D7X A;  4I9O A;  4F5S A;  2DBU A;  3MHS B;  2XVQ A;  1BM0 A;  2XVW A;  1HK1 A;  5DQF A;  1HK5 A;  4OT2 A;  3MHH B;  3FWC C;  3UIV A;  4N0U D;  4NAW B;  3W1S A;  2YDF A;  3WHR A;  1MM8 A;  4OR0 A;  2BXI A;  4IW1 A;  2JUH A;  1E7H A;  3VQI A;  4Z69 A;  2BXC A;  2I30 A;  4M70 B;  3SQJ A;  2BXP A;  3H3A A;  2DBX A;  4LA0 A;  1MUH A;  1E7C A;  2XMO A;  5IFO A;  2Z8I A;  5IIX A;  1NT2 B;  2QHB A;  5IJF A;  2LXT A;  4K2C A;  4WA6 B;  4L8U A;  1J7E A;  2EFC A;  4G03 A;  2EFD A;  5FUO A;  2DBW A;  1KXP D;  3B9M A;  5IIU A;  2BXE A;  2NNW A;  2LQI A;  4J2V A;  4GDK B;  4JK4 A;  1MIV A;  4GG2 A;  2CKX A;  2DG5 A;  3NVI A;  1MIY A;  1N5U A;  2BXL A;  2VUE A;  1E7G A;  2XVU A;  5HOZ A;  2OZB B;  4OTT A;  4PO0 A;  2OT3 A;  3NVM A;  3TDL A;  2ROH A;  2BXN A;  1LOT A;  5DBY A;  2V36 A;  3BPJ A;  1HK3 A;  4F5V A;  2BXA A;  2KWF A;  3ICX A;  4L9K A;  4TQ0 A;  2AJE A;  3CX9 A;  1E78 A;  4OTU A;  1BKE A;  4LUF A;  4K71 A;  1J78 A;  3WHS A;  3M99 C;  2BX8 A;  3SIU B;  3GQU A;  4BKE A;  4G01 A;  5D7G A;  1HA2 A;  1TF0 A;  2Z8J A;  2GUT A;  4ZBK A;  1E7A A;  4ZC6 A;  3V09 A;  5GIP A;  3LU7 A;  3NMU A;  1SB0 A;  2BXF A;  3A73 A;  4E99 A;  5GIN A;  2VDB A;  4LUH A;  5GIO A;  1HK4 A;  4DHX B;  2BXD A;  4Z9O A;  2EFE A;  2NQO A;  2KBZ A;  4N0F D;  1JNB A;  1BJ5 A;  3KJL A;  1IJG A;  4F5U A;  1GNJ A;  4EMX A;  1KDX A;  4C31 B;  3GA9 L;  1VZS A;  2XW0 A;  5ID9 A;  3V08 A;  1UOR A;  3H37 A;  2I2Z A;  4MBE C;  4BY9 C;  4ZUX V;  2Z8K A;  1O9X A;  2XVV A;  4N3Z A;  3FNM A;  2E0X A;  1MA9 A;  5IJ5 A; 
#chains in the Genus database with same CATH homology
 3LU6 A;  4ZCG A;  2QM6 A;  3NVK A;  2BXB A;  4HGK A;  3WHQ A;  4L9Q A;  5IIH A;  1AO6 A;  2BXH A;  3LU8 A;  1E7I A;  1H9Z A;  2VUF A;  2XSI A;  4G04 A;  4LB9 A;  3JRY A;  1H5W A;  4HGM B;  2XW1 A;  1E7B A;  3G9K D;  4ZBR A;  1VFI A;  1E7F A;  1FOU A;  2BXO A;  2LOQ A;  4IW2 A;  4ZBQ A;  1E7E A;  4FIP B;  2BXM A;  4W4U B;  4F5T A;  1GNI A;  3FWB C;  3GQX A;  5GHK A;  1HK2 A;  1KW2 A;  2E0Y A;  4FJC B;  4GDX A;  3V03 A;  1LNS A;  5BPK A;  5IJE A;  2BXQ A;  4FK5 B;  5B5T A;  5ID7 A;  4TQ1 A;  2DYM A;  2QMC A;  4S1Y A;  1TXU A;  2BXG A;  3A75 A;  3SIV B;  1MIW A;  2DYO A;  3KIK A;  3PLA A;  3JQZ A;  4GDL B;  2BXK A;  2EFH A;  4LB2 A;  3B9L A;  4F5S A;  2DBU A;  3MHS B;  2XVQ A;  1BM0 A;  2XVW A;  1HK1 A;  5DQF A;  1HK5 A;  4OT2 A;  3MHH B;  3FWC C;  3UIV A;  4N0U D;  4NAW B;  3W1S A;  2YDF A;  3WHR A;  4OR0 A;  2BXI A;  4IW1 A;  2JUH A;  1E7H A;  3VQI A;  4Z69 A;  2BXC A;  2I30 A;  4M70 B;  3SQJ A;  2BXP A;  3H3A A;  2DBX A;  4LA0 A;  1E7C A;  2XMO A;  5IFO A;  2Z8I A;  5IIX A;  1NT2 B;  2QHB A;  5IJF A;  4K2C A;  4WA6 B;  4L8U A;  1J7E A;  2EFC A;  4G03 A;  2EFD A;  5FUO A;  2DBW A;  1KXP D;  3B9M A;  5IIU A;  2BXE A;  2NNW A;  4J2V A;  4GDK B;  4JK4 A;  1MIV A;  4GG2 A;  2CKX A;  2DG5 A;  3NVI A;  1MIY A;  1N5U A;  2BXL A;  2VUE A;  1E7G A;  2XVU A;  5HOZ A;  2OZB B;  4OTT A;  4PO0 A;  2OT3 A;  3NVM A;  3TDL A;  2ROH A;  2BXN A;  1LOT A;  5DBY A;  2V36 A;  1HK3 A;  4F5V A;  2BXA A;  3ICX A;  4L9K A;  4TQ0 A;  2AJE A;  3CX9 A;  1E78 A;  4OTU A;  1BKE A;  4LUF A;  4K71 A;  1J78 A;  3WHS A;  3M99 C;  2BX8 A;  3SIU B;  3GQU A;  4BKE A;  4G01 A;  5D7G A;  1HA2 A;  1TF0 A;  2Z8J A;  4ZBK A;  1E7A A;  4ZC6 A;  3V09 A;  5GIP A;  3LU7 A;  3NMU A;  2BXF A;  3A73 A;  4E99 A;  5GIN A;  2VDB A;  4LUH A;  5GIO A;  1HK4 A;  4DHX B;  2BXD A;  4Z9O A;  2EFE A;  2NQO A;  2KBZ A;  4N0F D;  1JNB A;  1BJ5 A;  3KJL A;  1IJG A;  4F5U A;  1GNJ A;  4EMX A;  4C31 B;  3GA9 L;  1VZS A;  2XW0 A;  5ID9 A;  3V08 A;  1UOR A;  3H37 A;  2I2Z A;  4MBE C;  4BY9 C;  4ZUX V;  2Z8K A;  1O9X A;  2XVV A;  4N3Z A;  3FNM A;  2E0X A;  1MA9 A;  5IJ5 A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...