2BXKA

Human serum albumin complexed with myristate, azapropazone and indomethacin
Total Genus 226
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
226
sequence length
582
structure length
582
Chain Sequence
HKSEVAHRFKDLGEENFKALVLIAFAQYLQQCPFEDHVKLVNEVTEFAKTCVADESAENCDKSLHTLFGDKLCTVATLRETYGEMADCCAKQEPERNECFLQHKDDNPNLPRLVRPEVDVMCTAFHDNEETFLKKYLYEIARRHPYFYAPELLFFAKRYKAAFTECCQAADKAACLLPKLDELRDEGKASSAKQRLKCASLQKFGERAFKAWAVARLSQRFPKAEFAEVSKLVTDLTKVHTECCHGDLLECADDRADLAKYICENQDSISSKLKECCEKPLLEKSHCIAEVENDEMPADLPSLAADFVESKDVCKNYAEAKDVFLGMFLYEYARRHPDYSVVLLLRLAKTYETTLEKCCAAADPHECYAKVFDEFKPLVEEPQNLIKQNCELFEQLGEYKFQNALLVRYTKKVPQVSTPTLVEVSRNLGKVGSKCCKHPEAKRMPCAEDYLSVVLNQLCVLHEKTPVSDRVTKCCTESLVNRRPCFSALEVDETYVPKEFNAETFTFHADICTLSEKEEQIKKQTALVELVKHKPKATKEQLKAVMDDFAAFVEKCCKADDKETCFAEEGKKLVAASQAALG
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords SERUM ALBUMIN
publication title Structural Basis of the Drug-Binding Specificity of Human Serum Albumin.
pubmed doi rcsb
source organism Homo sapiens
molecule tags Transport protein
total genus 226
structure length 582
sequence length 582
ec nomenclature
pdb deposition date 2005-07-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00273 Serum_albumin Serum albumin family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 2bxkA03
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 2bxkA02
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 2bxkA04
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 2bxkA01
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 2bxkA06
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 2bxkA05
2BXPA 2BXHA 3B9LA 2XVUA 4G03A 2BXQA 3LU6A 2BXCA 1E7FA 4LUHA 1BJ5A 4L8UA 4LB9A 1HK4A 4G04A 4IW2A 1J78A 1HA2A 3JRYA 1HK3A 4LB2A 3V08A 2BXNA 4HGKA 4J2VA 3SQJA 5ID7A 4LUFA 1GNIA 3A73A 5DBYA 1HK2A 1E7EA 5IIXA 2BXFA 2XSIA 2BXAA 4K71A 2BXEA 4F5TA 1HK5A 5ID9A 5IJFA 3V09A 4ZBRA 5IJEA 2I30A 2BXDA 4JK4A 2XVWA 4F5UA 4F5VA 2VUEA 5HOZA 4N0FD 1E7GA 5DQFA 4L9QA 1TF0A 4L9KA 5IIHA 4E99A 3V03A 1H9ZA 4F5SA 1HK1A 2BXLA 1GNJA 2XVVA 2XW0A 1N5UA 4N0UD 1MA9A 2BXOA 4LA0A 4HGMB 3TDLA 3JQZA 5GHKA 1E78A 2BXMA 4OR0A 1E7HA 2BXGA 3B9MA 2BXBA 4BKEA 5IFOA 3LU8A 1O9XA 2BX8A 2XVQA 1E7IA 4S1YA 1BKEA 1E7AA 4IW1A 4OT2A 4PO0A 5IJ5A 3UIVA 2VDBA 1J7EA 4Z69A 3CX9A 4EMXA 1UORA 1BM0A 2VUFA 1AO6A 1KXPD 2YDFA 2BXIA 4K2CA 1KW2A 2I2ZA 1E7CA 2XW1A 5FUOA 5IIUA 2BXKA 1E7BA 4ZBQA 3LU7A 1LOTA
chains in the Genus database with same CATH superfamily
2BXPA 2BXHA 3B9LA 4C31B 2XVUA 4G03A 3KIKA 2BXQA 3LU6A 4TQ1A 2LQHA 3NVKA 2BXCA 1E7FA 4ZC6A 4GG2A 3PLAA 2LXTA 3GQXA 3G9KD 1LNSA 4LUHA 1BJ5A 4L8UA 4LB9A 2JUHA 1HK4A 4G04A 4IW2A 1J78A 1MIVA 1HA2A 2E0XA 2EFEA 3FWCC 3JRYA 1HK3A 4LB2A 4MBEC 2EFCA 3V08A 3GA9L 2BXNA 3NVIA 4HGKA 4J2VA 3SQJA 3VQIA 5ID7A 1NT2B 4LUFA 1GNIA 2K0NA 3A73A 5DBYA 1HK2A 2E0YA 1E7EA 2Z8KA 3KJLA 3ECPA 5IIXA 5BPKA 2BXFA 2DG5A 2XSIA 2EFDA 4GDKB 2KWFA 2BXAA 2Z8JA 2OT3A 4K71A 2BXEA 4FK5B 3WHQA 4F5TA 1HK5A 2EFHA 5ID9A 5IJFA 5GINA 3V09A 2QHBA 4TQ0A 3MHSB 4ZBRA 5IJEA 2I30A 2BXDA 1FOUA 4JK4A 2DYMA 2DBUA 2XVWA 5GIPA 4F5UA 4F5VA 2VUEA 5HOZA 4N0FD 1E7GA 5DQFA 4ZCGA 4ZBKA 2DBWA 4L9QA 2LQIA 2NQOA 1TF0A 3H3AA 4L9KA 5GIOA 5IIHA 4E99A 3V03A 4ZUXV 3GQUA 1H9ZA 4NAWB 3BPJA 2GUTA 4F5SA 4BY9C 2OZBB 1HK1A 2BXLA 1GNJA 2V36A 1MIWA 1MIYA 2XVVA 4FIPB 2XW0A 4W4UB 4FJCB 5D7GA 1N5UA 4N0UD 4OTUA 1MA9A 2KBZA 2BXOA 1MUSA 4I9OA 4LA0A 3MHHB 4HGMB 2AJEA 5B5TA 4DM0A 2AGHB 2NNWA 3TDLA 3JQZA 5GHKA 1E78A 2BXMA 4OR0A 1E7HA 1SB0A 2BXGA 3B9MA 3A75A 3WHRA 2BXBA 4M70B 5IFOA 4BKEA 1JNBA 1O9XA 3LU8A 2BX8A 2XVQA 1E7IA 2QM6A 4S1YA 1MM8A 1BKEA 1E7AA 4IW1A 4OT2A 4PO0A 5IJ5A 1H5WA 4G01A 3UIVA 2VDBA 1MUHA 2QMCA 1J7EA 3NVMA 4WA6B 2ROHA 1VFIA 4Z69A 3CX9A 4EMXA 1UORA 1VZSA 3ICXA 2LOQA 4GDXA 4D7XA 1BM0A 2VUFA 4N3ZA 1AO6A 1KXPD 2YDFA 3H37A 4Z9OA 2BXIA 3SIUB 4K2CA 1KW2A 2CKXA 3FWBC 2LXSA 3WHSA 4GDLB 2I2ZA 2Z8IA 1KDXA 1E7CA 2XW1A 2DBXA 5FUOA 4DHXB 1IJGA 5IIUA 3SIVB 3W1SA 2DYOA 2XMOA 3FNMA 3NMUA 2BXKA 1E7BA 3M99C 1TXUA 4OTTA 4ZBQA 3LU7A 1LOTA
chains in the Genus database with same CATH topology
2BXPA 2BXHA 3B9LA 4C31B 2XVUA 4G03A 3KIKA 2BXQA 3LU6A 4TQ1A 3NVKA 2BXCA 1E7FA 4ZC6A 4GG2A 3PLAA 3GQXA 3G9KD 1LNSA 4LUHA 1BJ5A 4L8UA 4LB9A 2JUHA 1HK4A 4G04A 4IW2A 1J78A 1MIVA 1HA2A 2E0XA 2EFEA 3FWCC 3JRYA 1HK3A 4LB2A 4MBEC 2EFCA 3V08A 3GA9L 2BXNA 3NVIA 4HGKA 4J2VA 3SQJA 3VQIA 5ID7A 1NT2B 4LUFA 1GNIA 3A73A 5DBYA 1HK2A 2E0YA 1E7EA 2Z8KA 3KJLA 5IIXA 5BPKA 2BXFA 2DG5A 2XSIA 2EFDA 4GDKB 2BXAA 2Z8JA 2OT3A 4K71A 2BXEA 4FK5B 3WHQA 4F5TA 1HK5A 2EFHA 5ID9A 5IJFA 5GINA 3V09A 2QHBA 4TQ0A 3MHSB 4ZBRA 5IJEA 2I30A 2BXDA 1FOUA 4JK4A 2DYMA 2DBUA 2XVWA 5GIPA 4F5UA 4F5VA 2VUEA 5HOZA 4N0FD 1E7GA 5DQFA 4ZCGA 4ZBKA 2DBWA 4L9QA 2NQOA 5GIOA 1TF0A 3H3AA 4L9KA 5IIHA 4E99A 3V03A 4ZUXV 3GQUA 1H9ZA 4NAWB 4F5SA 4BY9C 1HK1A 2BXLA 1GNJA 2V36A 1MIWA 1MIYA 2XVVA 4FIPB 2XW0A 4W4UB 4FJCB 5D7GA 1N5UA 4N0UD 4OTUA 1MA9A 2KBZA 2BXOA 4LA0A 3MHHB 4HGMB 2AJEA 5B5TA 2NNWA 3TDLA 3JQZA 5GHKA 1E78A 2BXMA 4OR0A 1E7HA 3WHRA 2BXGA 3B9MA 3A75A 2BXBA 4M70B 5IFOA 4BKEA 1JNBA 1O9XA 3LU8A 2BX8A 2XVQA 1E7IA 2QM6A 4S1YA 1BKEA 1E7AA 4IW1A 4OT2A 4PO0A 5IJ5A 1H5WA 4G01A 3UIVA 2VDBA 2QMCA 1J7EA 3NVMA 4WA6B 2ROHA 1VFIA 4Z69A 3CX9A 4EMXA 1UORA 1VZSA 3ICXA 2LOQA 4GDXA 2OZBB 1BM0A 2VUFA 4N3ZA 1AO6A 1KXPD 2YDFA 3H37A 4Z9OA 2BXIA 3SIUB 4K2CA 1KW2A 2CKXA 3FWBC 3WHSA 4GDLB 2I2ZA 2Z8IA 1E7CA 2XW1A 2DBXA 5FUOA 4DHXB 1IJGA 5IIUA 3SIVB 3W1SA 2DYOA 2XMOA 3FNMA 3NMUA 2BXKA 1E7BA 3M99C 1TXUA 4OTTA 4ZBQA 3LU7A 1LOTA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2BXP A;  2BXH A;  3B9L A;  2XVU A;  4G03 A;  2BXQ A;  3LU6 A;  2BXC A;  1E7F A;  4LUH A;  1BJ5 A;  4L8U A;  4LB9 A;  1HK4 A;  4G04 A;  4IW2 A;  1J78 A;  1HA2 A;  3JRY A;  1HK3 A;  4LB2 A;  3V08 A;  2BXN A;  4HGK A;  4J2V A;  3SQJ A;  5ID7 A;  4LUF A;  1GNI A;  3A73 A;  5DBY A;  1HK2 A;  1E7E A;  5IIX A;  2BXF A;  2XSI A;  2BXA A;  4K71 A;  2BXE A;  4F5T A;  1HK5 A;  5ID9 A;  5IJF A;  3V09 A;  4ZBR A;  5IJE A;  2I30 A;  2BXD A;  4JK4 A;  2XVW A;  4F5U A;  4F5V A;  2VUE A;  5HOZ A;  4N0F D;  1E7G A;  5DQF A;  4L9Q A;  1TF0 A;  4L9K A;  5IIH A;  4E99 A;  3V03 A;  1H9Z A;  4F5S A;  1HK1 A;  2BXL A;  1GNJ A;  2XVV A;  2XW0 A;  1N5U A;  4N0U D;  1MA9 A;  2BXO A;  4LA0 A;  4HGM B;  3TDL A;  3JQZ A;  5GHK A;  1E78 A;  2BXM A;  4OR0 A;  1E7H A;  2BXG A;  3B9M A;  2BXB A;  4BKE A;  5IFO A;  3LU8 A;  1O9X A;  2BX8 A;  2XVQ A;  1E7I A;  4S1Y A;  1BKE A;  1E7A A;  4IW1 A;  4OT2 A;  4PO0 A;  5IJ5 A;  3UIV A;  2VDB A;  1J7E A;  4Z69 A;  3CX9 A;  4EMX A;  1UOR A;  1BM0 A;  2VUF A;  1AO6 A;  1KXP D;  2YDF A;  2BXI A;  4K2C A;  1KW2 A;  2I2Z A;  1E7C A;  2XW1 A;  5FUO A;  5IIU A;  2BXK A;  1E7B A;  4ZBQ A;  3LU7 A;  1LOT A; 
#chains in the Genus database with same CATH topology
 2BXP A;  2BXH A;  3B9L A;  4C31 B;  2XVU A;  4G03 A;  3KIK A;  2BXQ A;  3LU6 A;  4TQ1 A;  2LQH A;  3NVK A;  2BXC A;  1E7F A;  4ZC6 A;  4GG2 A;  3PLA A;  2LXT A;  3GQX A;  3G9K D;  1LNS A;  4LUH A;  1BJ5 A;  4L8U A;  4LB9 A;  2JUH A;  1HK4 A;  4G04 A;  4IW2 A;  1J78 A;  1MIV A;  1HA2 A;  2E0X A;  2EFE A;  3FWC C;  3JRY A;  1HK3 A;  4LB2 A;  4MBE C;  2EFC A;  3V08 A;  3GA9 L;  2BXN A;  3NVI A;  4HGK A;  4J2V A;  3SQJ A;  3VQI A;  5ID7 A;  1NT2 B;  4LUF A;  1GNI A;  2K0N A;  3A73 A;  5DBY A;  1HK2 A;  2E0Y A;  1E7E A;  2Z8K A;  3KJL A;  3ECP A;  5IIX A;  5BPK A;  2BXF A;  2DG5 A;  2XSI A;  2EFD A;  4GDK B;  2KWF A;  2BXA A;  2Z8J A;  2OT3 A;  4K71 A;  2BXE A;  4FK5 B;  3WHQ A;  4F5T A;  1HK5 A;  2EFH A;  5ID9 A;  5IJF A;  5GIN A;  3V09 A;  2QHB A;  4TQ0 A;  3MHS B;  4ZBR A;  5IJE A;  2I30 A;  2BXD A;  1FOU A;  4JK4 A;  2DYM A;  2DBU A;  2XVW A;  5GIP A;  4F5U A;  4F5V A;  2VUE A;  5HOZ A;  4N0F D;  1E7G A;  5DQF A;  4ZCG A;  4ZBK A;  2DBW A;  4L9Q A;  2LQI A;  2NQO A;  1TF0 A;  3H3A A;  4L9K A;  5GIO A;  5IIH A;  4E99 A;  3V03 A;  4ZUX V;  3GQU A;  1H9Z A;  4NAW B;  3BPJ A;  2GUT A;  4F5S A;  4BY9 C;  2OZB B;  1HK1 A;  2BXL A;  1GNJ A;  2V36 A;  1MIW A;  1MIY A;  2XVV A;  4FIP B;  2XW0 A;  4W4U B;  4FJC B;  5D7G A;  1N5U A;  4N0U D;  4OTU A;  1MA9 A;  2KBZ A;  2BXO A;  1MUS A;  4I9O A;  4LA0 A;  3MHH B;  4HGM B;  2AJE A;  5B5T A;  4DM0 A;  2AGH B;  2NNW A;  3TDL A;  3JQZ A;  5GHK A;  1E78 A;  2BXM A;  4OR0 A;  1E7H A;  1SB0 A;  2BXG A;  3B9M A;  3A75 A;  3WHR A;  2BXB A;  4M70 B;  5IFO A;  4BKE A;  1JNB A;  1O9X A;  3LU8 A;  2BX8 A;  2XVQ A;  1E7I A;  2QM6 A;  4S1Y A;  1MM8 A;  1BKE A;  1E7A A;  4IW1 A;  4OT2 A;  4PO0 A;  5IJ5 A;  1H5W A;  4G01 A;  3UIV A;  2VDB A;  1MUH A;  2QMC A;  1J7E A;  3NVM A;  4WA6 B;  2ROH A;  1VFI A;  4Z69 A;  3CX9 A;  4EMX A;  1UOR A;  1VZS A;  3ICX A;  2LOQ A;  4GDX A;  4D7X A;  1BM0 A;  2VUF A;  4N3Z A;  1AO6 A;  1KXP D;  2YDF A;  3H37 A;  4Z9O A;  2BXI A;  3SIU B;  4K2C A;  1KW2 A;  2CKX A;  3FWB C;  2LXS A;  3WHS A;  4GDL B;  2I2Z A;  2Z8I A;  1KDX A;  1E7C A;  2XW1 A;  2DBX A;  5FUO A;  4DHX B;  1IJG A;  5IIU A;  3SIV B;  3W1S A;  2DYO A;  2XMO A;  3FNM A;  3NMU A;  2BXK A;  1E7B A;  3M99 C;  1TXU A;  4OTT A;  4ZBQ A;  3LU7 A;  1LOT A; 
#chains in the Genus database with same CATH homology
 2BXP A;  2BXH A;  3B9L A;  4C31 B;  2XVU A;  4G03 A;  3KIK A;  2BXQ A;  3LU6 A;  4TQ1 A;  3NVK A;  2BXC A;  1E7F A;  4ZC6 A;  4GG2 A;  3PLA A;  3GQX A;  3G9K D;  1LNS A;  4LUH A;  1BJ5 A;  4L8U A;  4LB9 A;  2JUH A;  1HK4 A;  4G04 A;  4IW2 A;  1J78 A;  1MIV A;  1HA2 A;  2E0X A;  2EFE A;  3FWC C;  3JRY A;  1HK3 A;  4LB2 A;  4MBE C;  2EFC A;  3V08 A;  3GA9 L;  2BXN A;  3NVI A;  4HGK A;  4J2V A;  3SQJ A;  3VQI A;  5ID7 A;  1NT2 B;  4LUF A;  1GNI A;  3A73 A;  5DBY A;  1HK2 A;  2E0Y A;  1E7E A;  2Z8K A;  3KJL A;  5IIX A;  5BPK A;  2BXF A;  2DG5 A;  2XSI A;  2EFD A;  4GDK B;  2BXA A;  2Z8J A;  2OT3 A;  4K71 A;  2BXE A;  4FK5 B;  3WHQ A;  4F5T A;  1HK5 A;  2EFH A;  5ID9 A;  5IJF A;  5GIN A;  3V09 A;  2QHB A;  4TQ0 A;  3MHS B;  4ZBR A;  5IJE A;  2I30 A;  2BXD A;  1FOU A;  4JK4 A;  2DYM A;  2DBU A;  2XVW A;  5GIP A;  4F5U A;  4F5V A;  2VUE A;  5HOZ A;  4N0F D;  1E7G A;  5DQF A;  4ZCG A;  4ZBK A;  2DBW A;  4L9Q A;  2NQO A;  5GIO A;  1TF0 A;  3H3A A;  4L9K A;  5IIH A;  4E99 A;  3V03 A;  4ZUX V;  3GQU A;  1H9Z A;  4NAW B;  4F5S A;  4BY9 C;  1HK1 A;  2BXL A;  1GNJ A;  2V36 A;  1MIW A;  1MIY A;  2XVV A;  4FIP B;  2XW0 A;  4W4U B;  4FJC B;  5D7G A;  1N5U A;  4N0U D;  4OTU A;  1MA9 A;  2KBZ A;  2BXO A;  4LA0 A;  3MHH B;  4HGM B;  2AJE A;  5B5T A;  2NNW A;  3TDL A;  3JQZ A;  5GHK A;  1E78 A;  2BXM A;  4OR0 A;  1E7H A;  3WHR A;  2BXG A;  3B9M A;  3A75 A;  2BXB A;  4M70 B;  5IFO A;  4BKE A;  1JNB A;  1O9X A;  3LU8 A;  2BX8 A;  2XVQ A;  1E7I A;  2QM6 A;  4S1Y A;  1BKE A;  1E7A A;  4IW1 A;  4OT2 A;  4PO0 A;  5IJ5 A;  1H5W A;  4G01 A;  3UIV A;  2VDB A;  2QMC A;  1J7E A;  3NVM A;  4WA6 B;  2ROH A;  1VFI A;  4Z69 A;  3CX9 A;  4EMX A;  1UOR A;  1VZS A;  3ICX A;  2LOQ A;  4GDX A;  2OZB B;  1BM0 A;  2VUF A;  4N3Z A;  1AO6 A;  1KXP D;  2YDF A;  3H37 A;  4Z9O A;  2BXI A;  3SIU B;  4K2C A;  1KW2 A;  2CKX A;  3FWB C;  3WHS A;  4GDL B;  2I2Z A;  2Z8I A;  1E7C A;  2XW1 A;  2DBX A;  5FUO A;  4DHX B;  1IJG A;  5IIU A;  3SIV B;  3W1S A;  2DYO A;  2XMO A;  3FNM A;  3NMU A;  2BXK A;  1E7B A;  3M99 C;  1TXU A;  4OTT A;  4ZBQ A;  3LU7 A;  1LOT A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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