2BXMA

Human serum albumin complexed with myristate and indomethacin
Total Genus 225
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
225
sequence length
582
structure length
582
Chain Sequence
HKSEVAHRFKDLGEENFKALVLIAFAQYLQQCPFEDHVKLVNEVTEFAKTCVADESAENCDKSLHTLFGDKLCTVATLRETYGEMADCCAKQEPERNECFLQHKDDNPNLPRLVRPEVDVMCTAFHDNEETFLKKYLYEIARRHPYFYAPELLFFAKRYKAAFTECCQAADKAACLLPKLDELRDEGKASSAKQRLKCASLQKFGERAFKAWAVARLSQRFPKAEFAEVSKLVTDLTKVHTECCHGDLLECADDRADLAKYICENQDSISSKLKECCEKPLLEKSHCIAEVENDEMPADLPSLAADFVESKDVCKNYAEAKDVFLGMFLYEYARRHPDYSVVLLLRLAKTYETTLEKCCAAADPHECYAKVFDEFKPLVEEPQNLIKQNCELFEQLGEYKFQNALLVRYTKKVPQVSTPTLVEVSRNLGKVGSKCCKHPEAKRMPCAEDYLSVVLNQLCVLHEKTPVSDRVTKCCTESLVNRRPCFSALEVDETYVPKEFNAETFTFHADICTLSEKERQIKKQTALVELVKHKPKATKEQLKAVMDDFAAFVEKCCKADDKETCFAEEGKKLVAASQAALG
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule keywords SERUM ALBUMIN
publication title Structural Basis of the Drug-Binding Specificity of Human Serum Albumin.
pubmed doi rcsb
source organism Homo sapiens
molecule tags Transport protein
total genus 225
structure length 582
sequence length 582
ec nomenclature
pdb deposition date 2005-07-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00273 Serum_albumin Serum albumin family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 2bxmA03
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 2bxmA02
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 2bxmA04
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 2bxmA01
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 2bxmA06
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 2bxmA05
2BXEA 1J7EA 2BXGA 5ID9A 2XVWA 5IJ5A 1KW2A 3V09A 5IIUA 4LB9A 2BX8A 5DBYA 3TDLA 1E78A 4F5TA 2VDBA 3V03A 1LOTA 5IJFA 1E7EA 4K71A 2XW1A 1GNIA 4ZBRA 1BKEA 1MA9A 2BXFA 2BXQA 4PO0A 4IW1A 1HK1A 2BXDA 5IFOA 2BXCA 5IJEA 2BXAA 4S1YA 1HA2A 4E99A 4JK4A 4F5UA 4LUFA 1E7CA 1E7HA 1O9XA 5GHKA 5FUOA 4L9QA 3JQZA 1AO6A 1H9ZA 1UORA 1BJ5A 1GNJA 1HK4A 1HK2A 1E7FA 4ZBQA 3B9LA 4OR0A 1BM0A 4LUHA 4F5VA 1TF0A 4L9KA 3LU7A 5DQFA 4L8UA 3LU6A 1HK5A 2XW0A 4N0UD 4IW2A 4K2CA 4J2VA 2YDFA 2BXIA 3JRYA 4G03A 4G04A 3B9MA 1N5UA 4EMXA 3A73A 5IIHA 2XVUA 2XVQA 5IIXA 2I2ZA 1J78A 4Z69A 3CX9A 2I30A 1E7BA 2VUFA 4HGMB 3SQJA 5HOZA 3UIVA 3LU8A 2BXLA 4LB2A 1E7GA 2BXHA 2BXNA 4OT2A 2BXOA 2BXMA 1E7IA 4F5SA 2BXBA 4LA0A 1E7AA 2XVVA 2BXPA 1KXPD 2VUEA 3V08A 4HGKA 4N0FD 4BKEA 2XSIA 1HK3A 5ID7A 2BXKA
chains in the Genus database with same CATH superfamily
2BXEA 1J7EA 1MIYA 2BXGA 2DYOA 2KWFA 5ID9A 3BPJA 3FNMA 3SIUB 2XVWA 3GQXA 3ICXA 5GINA 2DBUA 5IJ5A 4NAWB 1KW2A 3V09A 5IIUA 4DHXB 4LB9A 2BX8A 5DBYA 2CKXA 1TXUA 2Z8KA 3TDLA 1MIWA 1VZSA 2LXSA 1MIVA 1E78A 2DYMA 3MHHB 4F5TA 2VDBA 2Z8IA 3V03A 1LOTA 3WHRA 5IJFA 1E7EA 4K71A 4ZBKA 1FOUA 2XW1A 4G01A 2AJEA 4I9OA 1GNIA 4ZBRA 1BKEA 2K0NA 2OZBB 4ZCGA 1MA9A 4C31B 3NVIA 2BXFA 2BXQA 2LQIA 4N3ZA 4PO0A 4GDKB 1MUSA 4IW1A 1HK1A 2BXDA 2V36A 5D7GA 5IFOA 1MUHA 2QMCA 4BY9C 3VQIA 2NQOA 3WHSA 1SB0A 2BXCA 2LOQA 5IJEA 2BXAA 4S1YA 1HA2A 4M70B 2DBXA 4E99A 4JK4A 4F5UA 3A75A 3H3AA 4LUFA 1E7CA 2Z8JA 1E7HA 2EFDA 1JNBA 1O9XA 5GHKA 5FUOA 2QHBA 3SIVB 4L9QA 3JQZA 1AO6A 1H9ZA 2QM6A 2EFEA 1UORA 1BJ5A 1GNJA 1HK4A 1HK2A 3GQUA 3M99C 4GDLB 4ZC6A 2E0XA 1E7FA 4ZBQA 1LNSA 4W4UB 4GDXA 3B9LA 4Z9OA 4OR0A 1BM0A 2DG5A 4LUHA 4D7XA 4F5VA 1TF0A 2E0YA 4L9KA 3WHQA 3LU7A 5DQFA 4L8UA 3LU6A 1HK5A 3MHSB 2EFCA 2XW0A 4N0UD 4IW2A 4K2CA 1KDXA 4J2VA 2YDFA 2BXIA 4DM0A 3KJLA 3JRYA 4G03A 4G04A 3B9MA 2KBZA 2JUHA 3GA9L 1N5UA 3FWBC 3NVKA 4EMXA 3A73A 3KIKA 5B5TA 4FK5B 2XVUA 5IIHA 2XVQA 4GG2A 2I2ZA 5IIXA 2XMOA 3FWCC 5BPKA 4TQ1A 1J78A 4Z69A 4FJCB 4FIPB 4MBEC 4OTTA 3CX9A 1NT2B 2I30A 1E7BA 2NNWA 4WA6B 2VUFA 2GUTA 4HGMB 4OTUA 3SQJA 5HOZA 3W1SA 3UIVA 3LU8A 2AGHB 3NMUA 2BXLA 2LQHA 1H5WA 1VFIA 4LB2A 1MM8A 1E7GA 2BXHA 2BXNA 3PLAA 5GIPA 4OT2A 2BXOA 4ZUXV 2BXMA 1E7IA 1IJGA 2DBWA 4F5SA 3NVMA 2ROHA 2EFHA 2BXBA 4LA0A 1E7AA 2XVVA 2BXPA 1KXPD 2LXTA 2VUEA 3V08A 3ECPA 2OT3A 4HGKA 4N0FD 4BKEA 2XSIA 3G9KD 5GIOA 1HK3A 4TQ0A 5ID7A 2BXKA 3H37A
chains in the Genus database with same CATH topology
2BXEA 1J7EA 1MIYA 2BXGA 2DYOA 5ID9A 3FNMA 3SIUB 2XVWA 3GQXA 3ICXA 5GINA 2DBUA 5IJ5A 4NAWB 1KW2A 3V09A 5IIUA 4DHXB 4LB9A 2BX8A 5DBYA 2CKXA 1TXUA 2Z8KA 3TDLA 1MIWA 1VZSA 1MIVA 1E78A 2DYMA 3MHHB 4F5TA 2VDBA 2Z8IA 3V03A 1LOTA 3WHRA 5IJFA 1E7EA 4K71A 4ZBKA 1FOUA 2XW1A 4G01A 2AJEA 1GNIA 4ZBRA 1BKEA 2OZBB 4ZCGA 1MA9A 4C31B 3NVIA 2BXFA 2BXQA 4N3ZA 4PO0A 4GDKB 4IW1A 1HK1A 2BXDA 2V36A 5D7GA 5IFOA 4BY9C 2QMCA 3VQIA 2NQOA 3WHSA 2BXCA 2LOQA 5IJEA 2BXAA 4S1YA 1HA2A 4M70B 2DBXA 4E99A 4JK4A 4F5UA 3A75A 3H3AA 4LUFA 1E7CA 2Z8JA 1E7HA 2EFDA 1JNBA 1O9XA 5GHKA 5FUOA 2QHBA 3SIVB 4L9QA 3JQZA 1AO6A 1H9ZA 2QM6A 2EFEA 1UORA 1BJ5A 1GNJA 1HK4A 1HK2A 3GQUA 3M99C 4GDLB 4ZC6A 2E0XA 1E7FA 4ZBQA 1LNSA 4W4UB 4GDXA 3B9LA 4Z9OA 4OR0A 1BM0A 2DG5A 4LUHA 4F5VA 1TF0A 2E0YA 4L9KA 3WHQA 3LU7A 5DQFA 4L8UA 3LU6A 1HK5A 3MHSB 2EFCA 2XW0A 4N0UD 4IW2A 4K2CA 4J2VA 2YDFA 2BXIA 3KJLA 3JRYA 4G03A 4G04A 3B9MA 2KBZA 2JUHA 3GA9L 1N5UA 3FWBC 3NVKA 4EMXA 3A73A 3KIKA 5B5TA 4FK5B 2XVUA 5IIHA 2XVQA 4GG2A 2I2ZA 5IIXA 2XMOA 3FWCC 5BPKA 4TQ1A 1J78A 4Z69A 4FJCB 4FIPB 4MBEC 4OTTA 3CX9A 1NT2B 2I30A 1E7BA 2NNWA 4WA6B 2VUFA 4HGMB 4OTUA 3SQJA 3W1SA 5HOZA 3UIVA 3LU8A 3NMUA 2BXLA 1H5WA 1VFIA 4LB2A 1E7GA 2BXHA 2BXNA 3PLAA 5GIPA 4OT2A 2BXOA 4ZUXV 2BXMA 1E7IA 1IJGA 2DBWA 4F5SA 3NVMA 2ROHA 2EFHA 2BXBA 4LA0A 1E7AA 2XVVA 2BXPA 1KXPD 2VUEA 3V08A 2OT3A 4HGKA 4N0FD 4BKEA 2XSIA 3G9KD 5GIOA 1HK3A 4TQ0A 5ID7A 2BXKA 3H37A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2BXE A;  1J7E A;  2BXG A;  5ID9 A;  2XVW A;  5IJ5 A;  1KW2 A;  3V09 A;  5IIU A;  4LB9 A;  2BX8 A;  5DBY A;  3TDL A;  1E78 A;  4F5T A;  2VDB A;  3V03 A;  1LOT A;  5IJF A;  1E7E A;  4K71 A;  2XW1 A;  1GNI A;  4ZBR A;  1BKE A;  1MA9 A;  2BXF A;  2BXQ A;  4PO0 A;  4IW1 A;  1HK1 A;  2BXD A;  5IFO A;  2BXC A;  5IJE A;  2BXA A;  4S1Y A;  1HA2 A;  4E99 A;  4JK4 A;  4F5U A;  4LUF A;  1E7C A;  1E7H A;  1O9X A;  5GHK A;  5FUO A;  4L9Q A;  3JQZ A;  1AO6 A;  1H9Z A;  1UOR A;  1BJ5 A;  1GNJ A;  1HK4 A;  1HK2 A;  1E7F A;  4ZBQ A;  3B9L A;  4OR0 A;  1BM0 A;  4LUH A;  4F5V A;  1TF0 A;  4L9K A;  3LU7 A;  5DQF A;  4L8U A;  3LU6 A;  1HK5 A;  2XW0 A;  4N0U D;  4IW2 A;  4K2C A;  4J2V A;  2YDF A;  2BXI A;  3JRY A;  4G03 A;  4G04 A;  3B9M A;  1N5U A;  4EMX A;  3A73 A;  5IIH A;  2XVU A;  2XVQ A;  5IIX A;  2I2Z A;  1J78 A;  4Z69 A;  3CX9 A;  2I30 A;  1E7B A;  2VUF A;  4HGM B;  3SQJ A;  5HOZ A;  3UIV A;  3LU8 A;  2BXL A;  4LB2 A;  1E7G A;  2BXH A;  2BXN A;  4OT2 A;  2BXO A;  2BXM A;  1E7I A;  4F5S A;  2BXB A;  4LA0 A;  1E7A A;  2XVV A;  2BXP A;  1KXP D;  2VUE A;  3V08 A;  4HGK A;  4N0F D;  4BKE A;  2XSI A;  1HK3 A;  5ID7 A;  2BXK A; 
#chains in the Genus database with same CATH topology
 2BXE A;  1J7E A;  1MIY A;  2BXG A;  2DYO A;  2KWF A;  5ID9 A;  3BPJ A;  3FNM A;  3SIU B;  2XVW A;  3GQX A;  3ICX A;  5GIN A;  2DBU A;  5IJ5 A;  4NAW B;  1KW2 A;  3V09 A;  5IIU A;  4DHX B;  4LB9 A;  2BX8 A;  5DBY A;  2CKX A;  1TXU A;  2Z8K A;  3TDL A;  1MIW A;  1VZS A;  2LXS A;  1MIV A;  1E78 A;  2DYM A;  3MHH B;  4F5T A;  2VDB A;  2Z8I A;  3V03 A;  1LOT A;  3WHR A;  5IJF A;  1E7E A;  4K71 A;  4ZBK A;  1FOU A;  2XW1 A;  4G01 A;  2AJE A;  4I9O A;  1GNI A;  4ZBR A;  1BKE A;  2K0N A;  2OZB B;  4ZCG A;  1MA9 A;  4C31 B;  3NVI A;  2BXF A;  2BXQ A;  2LQI A;  4N3Z A;  4PO0 A;  4GDK B;  1MUS A;  4IW1 A;  1HK1 A;  2BXD A;  2V36 A;  5D7G A;  5IFO A;  1MUH A;  2QMC A;  4BY9 C;  3VQI A;  2NQO A;  3WHS A;  1SB0 A;  2BXC A;  2LOQ A;  5IJE A;  2BXA A;  4S1Y A;  1HA2 A;  4M70 B;  2DBX A;  4E99 A;  4JK4 A;  4F5U A;  3A75 A;  3H3A A;  4LUF A;  1E7C A;  2Z8J A;  1E7H A;  2EFD A;  1JNB A;  1O9X A;  5GHK A;  5FUO A;  2QHB A;  3SIV B;  4L9Q A;  3JQZ A;  1AO6 A;  1H9Z A;  2QM6 A;  2EFE A;  1UOR A;  1BJ5 A;  1GNJ A;  1HK4 A;  1HK2 A;  3GQU A;  3M99 C;  4GDL B;  4ZC6 A;  2E0X A;  1E7F A;  4ZBQ A;  1LNS A;  4W4U B;  4GDX A;  3B9L A;  4Z9O A;  4OR0 A;  1BM0 A;  2DG5 A;  4LUH A;  4D7X A;  4F5V A;  1TF0 A;  2E0Y A;  4L9K A;  3WHQ A;  3LU7 A;  5DQF A;  4L8U A;  3LU6 A;  1HK5 A;  3MHS B;  2EFC A;  2XW0 A;  4N0U D;  4IW2 A;  4K2C A;  1KDX A;  4J2V A;  2YDF A;  2BXI A;  4DM0 A;  3KJL A;  3JRY A;  4G03 A;  4G04 A;  3B9M A;  2KBZ A;  2JUH A;  3GA9 L;  1N5U A;  3FWB C;  3NVK A;  4EMX A;  3A73 A;  3KIK A;  5B5T A;  4FK5 B;  2XVU A;  5IIH A;  2XVQ A;  4GG2 A;  2I2Z A;  5IIX A;  2XMO A;  3FWC C;  5BPK A;  4TQ1 A;  1J78 A;  4Z69 A;  4FJC B;  4FIP B;  4MBE C;  4OTT A;  3CX9 A;  1NT2 B;  2I30 A;  1E7B A;  2NNW A;  4WA6 B;  2VUF A;  2GUT A;  4HGM B;  4OTU A;  3SQJ A;  5HOZ A;  3W1S A;  3UIV A;  3LU8 A;  2AGH B;  3NMU A;  2BXL A;  2LQH A;  1H5W A;  1VFI A;  4LB2 A;  1MM8 A;  1E7G A;  2BXH A;  2BXN A;  3PLA A;  5GIP A;  4OT2 A;  2BXO A;  4ZUX V;  2BXM A;  1E7I A;  1IJG A;  2DBW A;  4F5S A;  3NVM A;  2ROH A;  2EFH A;  2BXB A;  4LA0 A;  1E7A A;  2XVV A;  2BXP A;  1KXP D;  2LXT A;  2VUE A;  3V08 A;  3ECP A;  2OT3 A;  4HGK A;  4N0F D;  4BKE A;  2XSI A;  3G9K D;  5GIO A;  1HK3 A;  4TQ0 A;  5ID7 A;  2BXK A;  3H37 A; 
#chains in the Genus database with same CATH homology
 2BXE A;  1J7E A;  1MIY A;  2BXG A;  2DYO A;  5ID9 A;  3FNM A;  3SIU B;  2XVW A;  3GQX A;  3ICX A;  5GIN A;  2DBU A;  5IJ5 A;  4NAW B;  1KW2 A;  3V09 A;  5IIU A;  4DHX B;  4LB9 A;  2BX8 A;  5DBY A;  2CKX A;  1TXU A;  2Z8K A;  3TDL A;  1MIW A;  1VZS A;  1MIV A;  1E78 A;  2DYM A;  3MHH B;  4F5T A;  2VDB A;  2Z8I A;  3V03 A;  1LOT A;  3WHR A;  5IJF A;  1E7E A;  4K71 A;  4ZBK A;  1FOU A;  2XW1 A;  4G01 A;  2AJE A;  1GNI A;  4ZBR A;  1BKE A;  2OZB B;  4ZCG A;  1MA9 A;  4C31 B;  3NVI A;  2BXF A;  2BXQ A;  4N3Z A;  4PO0 A;  4GDK B;  4IW1 A;  1HK1 A;  2BXD A;  2V36 A;  5D7G A;  5IFO A;  4BY9 C;  2QMC A;  3VQI A;  2NQO A;  3WHS A;  2BXC A;  2LOQ A;  5IJE A;  2BXA A;  4S1Y A;  1HA2 A;  4M70 B;  2DBX A;  4E99 A;  4JK4 A;  4F5U A;  3A75 A;  3H3A A;  4LUF A;  1E7C A;  2Z8J A;  1E7H A;  2EFD A;  1JNB A;  1O9X A;  5GHK A;  5FUO A;  2QHB A;  3SIV B;  4L9Q A;  3JQZ A;  1AO6 A;  1H9Z A;  2QM6 A;  2EFE A;  1UOR A;  1BJ5 A;  1GNJ A;  1HK4 A;  1HK2 A;  3GQU A;  3M99 C;  4GDL B;  4ZC6 A;  2E0X A;  1E7F A;  4ZBQ A;  1LNS A;  4W4U B;  4GDX A;  3B9L A;  4Z9O A;  4OR0 A;  1BM0 A;  2DG5 A;  4LUH A;  4F5V A;  1TF0 A;  2E0Y A;  4L9K A;  3WHQ A;  3LU7 A;  5DQF A;  4L8U A;  3LU6 A;  1HK5 A;  3MHS B;  2EFC A;  2XW0 A;  4N0U D;  4IW2 A;  4K2C A;  4J2V A;  2YDF A;  2BXI A;  3KJL A;  3JRY A;  4G03 A;  4G04 A;  3B9M A;  2KBZ A;  2JUH A;  3GA9 L;  1N5U A;  3FWB C;  3NVK A;  4EMX A;  3A73 A;  3KIK A;  5B5T A;  4FK5 B;  2XVU A;  5IIH A;  2XVQ A;  4GG2 A;  2I2Z A;  5IIX A;  2XMO A;  3FWC C;  5BPK A;  4TQ1 A;  1J78 A;  4Z69 A;  4FJC B;  4FIP B;  4MBE C;  4OTT A;  3CX9 A;  1NT2 B;  2I30 A;  1E7B A;  2NNW A;  4WA6 B;  2VUF A;  4HGM B;  4OTU A;  3SQJ A;  3W1S A;  5HOZ A;  3UIV A;  3LU8 A;  3NMU A;  2BXL A;  1H5W A;  1VFI A;  4LB2 A;  1E7G A;  2BXH A;  2BXN A;  3PLA A;  5GIP A;  4OT2 A;  2BXO A;  4ZUX V;  2BXM A;  1E7I A;  1IJG A;  2DBW A;  4F5S A;  3NVM A;  2ROH A;  2EFH A;  2BXB A;  4LA0 A;  1E7A A;  2XVV A;  2BXP A;  1KXP D;  2VUE A;  3V08 A;  2OT3 A;  4HGK A;  4N0F D;  4BKE A;  2XSI A;  3G9K D;  5GIO A;  1HK3 A;  4TQ0 A;  5ID7 A;  2BXK A;  3H37 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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