2BXPA

Human serum albumin complexed with myristate and phenylbutazone
Total Genus 223
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
223
sequence length
581
structure length
581
Chain Sequence
HKSEVAHRFKDLGEENFKALVLIAFAQYLQQCPFEDHVKLVNEVTEFAKTCVADESAENCDKSLHTLFGDKLCTVATLRETYGEMADCCAKQEPERNECFLQHKDDNPNLPRLVRPEVDVMCTAFHDNEETFLKKYLYEIARRHPYFYAPELLFFAKRYKAAFTECCQAADKAACLLPKLDELRDEGKASSAKQRLKCASLQKFGERAFKAWAVARLSQRFPKAEFAEVSKLVTDLTKVHTECCHGDLLECADDRADLAKYICENQDSISSKLKECCEKPLLEKSHCIAEVENDEMPADLPSLAADFVESKDVCKNYAEAKDVFLGMFLYEYARRHPDYSVVLLLRLAKTYETTLEKCCAAADPHECYAKVFDEFKPLVEEPQNLIKQNCELFEQLGEYKFQNALLVRYTKKVPQVSTPTLVEVSRNLGKVGSKCCKHPEAKRMPCAEDYLSVVLNQLCVLHEKTPVSDRVTKCCTESLVNRRPCFSALEVDETYVPKEFNAETFTFHADICTLSEKERQIKKQTALVELVKHKPKATKEQLKAVMDDFAAFVEKCCKADDKETCFAEEGKKLVAASQAAL
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule keywords SERUM ALBUMIN
publication title Structural Basis of the Drug-Binding Specificity of Human Serum Albumin.
pubmed doi rcsb
source organism Homo sapiens
molecule tags Transport protein
total genus 223
structure length 581
sequence length 581
ec nomenclature
pdb deposition date 2005-07-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00273 Serum_albumin Serum albumin family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 2bxpA03
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 2bxpA02
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 2bxpA04
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 2bxpA01
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 2bxpA06
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 2bxpA05
1E7HA 4PO0A 1E7AA 5ID7A 1KW2A 2XW1A 2VUEA 4LUFA 1E78A 1HK5A 2BXLA 4J2VA 1TF0A 5HOZA 3B9LA 3LU6A 3LU8A 3JQZA 4EMXA 5GHKA 4K71A 2XVWA 3V09A 3LU7A 4LA0A 5ID9A 4E99A 5IJEA 1HA2A 2BXOA 2BXIA 5IJFA 4N0UD 1HK3A 4IW2A 1E7BA 4BKEA 2I30A 1E7EA 4LB9A 5IIUA 1H9ZA 1E7FA 1GNJA 4L8UA 2BXMA 4IW1A 3V08A 2BXBA 4F5UA 1UORA 1E7CA 2XVUA 2BXPA 1E7GA 4LUHA 1HK2A 1LOTA 2YDFA 5IJ5A 3JRYA 2XVQA 3B9MA 2VUFA 2BXEA 3CX9A 2BXGA 3UIVA 1HK4A 2BXNA 4L9QA 1O9XA 4OT2A 4Z69A 2BX8A 4F5SA 2XVVA 1BKEA 3SQJA 2BXKA 1GNIA 4LB2A 5FUOA 2XSIA 1AO6A 5IIHA 4OR0A 5IIXA 5DQFA 2BXCA 4L9KA 4HGKA 5IFOA 1BJ5A 4K2CA 2BXHA 1HK1A 4ZBQA 1J78A 4HGMB 4G03A 2BXFA 3TDLA 4JK4A 5DBYA 2VDBA 4G04A 2BXQA 3A73A 4S1YA 1N5UA 1E7IA 3V03A 2BXAA 1J7EA 4F5VA 2I2ZA 4N0FD 4ZBRA 4F5TA 1BM0A 1MA9A 1KXPD 2XW0A 2BXDA
chains in the Genus database with same CATH superfamily
1E7HA 3ICXA 1E7AA 4PO0A 1KW2A 4TQ1A 5ID7A 1SB0A 2DYMA 2XW1A 2OZBB 3SIVB 2EFHA 2VUEA 2Z8KA 4LUFA 4OTTA 1E78A 2K0NA 3FWCC 4G01A 2E0XA 1HK5A 2BXLA 4J2VA 4TQ0A 1TF0A 5HOZA 3GQXA 3WHQA 3B9LA 2KWFA 3FWBC 3LU6A 4C31B 3ECPA 3LU8A 2V36A 3JQZA 4EMXA 1KDXA 1LNSA 5GHKA 2DYOA 4K71A 2JUHA 2XVWA 1VZSA 3V09A 3LU7A 4LA0A 5ID9A 4ZC6A 4ZBKA 4ZCGA 4E99A 5IJEA 1HA2A 2BXOA 2BXIA 4N3ZA 3GA9L 5D7GA 5GIPA 5IJFA 4N0UD 1NT2B 5B5TA 2AJEA 3SIUB 1MIWA 2EFDA 2LQIA 1HK3A 4IW2A 4Z9OA 1E7BA 3G9KD 4BKEA 2I30A 1E7EA 2NNWA 2EFEA 1H9ZA 4LB9A 5IIUA 2DG5A 1E7FA 3KIKA 1GNJA 4L8UA 2BXMA 3FNMA 4IW1A 2OT3A 3H37A 3V08A 2BXBA 2Z8JA 4F5UA 1UORA 1E7CA 2XVUA 2BXPA 1E7GA 1H5WA 4GG2A 4LUHA 4FK5B 1HK2A 1LOTA 2YDFA 2Z8IA 3WHRA 5IJ5A 1MUHA 3JRYA 2XVQA 3B9MA 2QM6A 2VUFA 2BXEA 3CX9A 2BXGA 2LQHA 3UIVA 1HK4A 3BPJA 1MIYA 2BXNA 3MHHB 4L9QA 1O9XA 4OT2A 4ZUXV 4Z69A 2LOQA 4FJCB 2BX8A 4F5SA 2XVVA 4GDLB 1BKEA 3MHSB 1MM8A 3SQJA 3NMUA 2BXKA 2E0YA 1GNIA 4NAWB 1TXUA 2LXTA 2GUTA 2EFCA 4LB2A 2AGHB 5FUOA 1MUSA 2XSIA 1AO6A 5IIHA 4OR0A 5IIXA 5DQFA 2BXCA 5BPKA 4GDKB 4L9KA 2NQOA 4HGKA 1FOUA 3W1SA 2LXSA 4MBEC 5IFOA 1BJ5A 4K2CA 2BXHA 1MIVA 1HK1A 2QMCA 4DM0A 4ZBQA 4I9OA 3WHSA 1J78A 4HGMB 2DBWA 4G03A 3NVIA 2QHBA 2BXFA 4WA6B 3A75A 3TDLA 2CKXA 2ROHA 3NVKA 5GIOA 3KJLA 4JK4A 5DBYA 2VDBA 4FIPB 3NVMA 4G04A 3M99C 2BXQA 4M70B 4OTUA 3A73A 2XMOA 3H3AA 4GDXA 1VFIA 4S1YA 1N5UA 1E7IA 3PLAA 2DBUA 2DBXA 3V03A 2BXAA 4D7XA 5GINA 1J7EA 4F5VA 4BY9C 1JNBA 2I2ZA 2KBZA 4N0FD 1IJGA 3GQUA 4ZBRA 4F5TA 4W4UB 3VQIA 1BM0A 1MA9A 1KXPD 2XW0A 2BXDA 4DHXB
chains in the Genus database with same CATH topology
1E7HA 3ICXA 1E7AA 4PO0A 1KW2A 4TQ1A 5ID7A 2DYMA 2XW1A 2OZBB 3SIVB 2EFHA 2VUEA 2Z8KA 4LUFA 4OTTA 1E78A 3FWCC 4G01A 2E0XA 1HK5A 2BXLA 4J2VA 4TQ0A 1TF0A 5HOZA 3GQXA 3WHQA 3B9LA 3FWBC 3LU6A 4C31B 3LU8A 2V36A 3JQZA 4EMXA 1LNSA 5GHKA 2DYOA 4K71A 2JUHA 2XVWA 1VZSA 3V09A 3LU7A 4LA0A 5ID9A 4ZC6A 4ZBKA 4ZCGA 4E99A 5IJEA 1HA2A 2BXOA 2BXIA 4N3ZA 3GA9L 5D7GA 5GIPA 5IJFA 4N0UD 1NT2B 5B5TA 2AJEA 3SIUB 1MIWA 2EFDA 1HK3A 4IW2A 4Z9OA 1E7BA 3G9KD 4BKEA 2I30A 1E7EA 2NNWA 2EFEA 1H9ZA 4LB9A 5IIUA 2DG5A 1E7FA 3KIKA 1GNJA 4L8UA 2BXMA 3FNMA 4IW1A 2OT3A 3H37A 3V08A 2BXBA 2Z8JA 4F5UA 1UORA 1E7CA 2XVUA 2BXPA 1E7GA 1H5WA 4GG2A 4LUHA 4FK5B 1HK2A 1LOTA 2YDFA 2Z8IA 3WHRA 5IJ5A 3JRYA 2XVQA 3B9MA 2QM6A 2VUFA 2BXEA 3CX9A 2BXGA 3UIVA 1HK4A 1MIYA 2BXNA 3MHHB 4L9QA 1O9XA 4OT2A 4ZUXV 4Z69A 2LOQA 4FJCB 2BX8A 4F5SA 2XVVA 4GDLB 1BKEA 3MHSB 3SQJA 3NMUA 2BXKA 2E0YA 1GNIA 4NAWB 1TXUA 4LB2A 2EFCA 5FUOA 2XSIA 1AO6A 5IIHA 4OR0A 5IIXA 5DQFA 2BXCA 5BPKA 4GDKB 4L9KA 2NQOA 4HGKA 1FOUA 3W1SA 4MBEC 5IFOA 1BJ5A 4K2CA 2BXHA 1MIVA 1HK1A 2QMCA 4ZBQA 3WHSA 1J78A 4HGMB 2DBWA 4G03A 3NVIA 2QHBA 2BXFA 4WA6B 3A75A 3TDLA 2CKXA 2ROHA 3NVKA 5GIOA 3KJLA 4JK4A 5DBYA 2VDBA 4FIPB 3NVMA 4G04A 3M99C 2BXQA 4M70B 4OTUA 3A73A 2XMOA 3H3AA 4GDXA 1VFIA 4S1YA 1N5UA 1E7IA 3PLAA 2DBUA 2DBXA 3V03A 2BXAA 5GINA 1J7EA 4F5VA 4BY9C 1JNBA 2I2ZA 2KBZA 4N0FD 1IJGA 3GQUA 4ZBRA 4F5TA 4W4UB 3VQIA 1BM0A 1MA9A 1KXPD 2XW0A 2BXDA 4DHXB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1E7H A;  4PO0 A;  1E7A A;  5ID7 A;  1KW2 A;  2XW1 A;  2VUE A;  4LUF A;  1E78 A;  1HK5 A;  2BXL A;  4J2V A;  1TF0 A;  5HOZ A;  3B9L A;  3LU6 A;  3LU8 A;  3JQZ A;  4EMX A;  5GHK A;  4K71 A;  2XVW A;  3V09 A;  3LU7 A;  4LA0 A;  5ID9 A;  4E99 A;  5IJE A;  1HA2 A;  2BXO A;  2BXI A;  5IJF A;  4N0U D;  1HK3 A;  4IW2 A;  1E7B A;  4BKE A;  2I30 A;  1E7E A;  4LB9 A;  5IIU A;  1H9Z A;  1E7F A;  1GNJ A;  4L8U A;  2BXM A;  4IW1 A;  3V08 A;  2BXB A;  4F5U A;  1UOR A;  1E7C A;  2XVU A;  2BXP A;  1E7G A;  4LUH A;  1HK2 A;  1LOT A;  2YDF A;  5IJ5 A;  3JRY A;  2XVQ A;  3B9M A;  2VUF A;  2BXE A;  3CX9 A;  2BXG A;  3UIV A;  1HK4 A;  2BXN A;  4L9Q A;  1O9X A;  4OT2 A;  4Z69 A;  2BX8 A;  4F5S A;  2XVV A;  1BKE A;  3SQJ A;  2BXK A;  1GNI A;  4LB2 A;  5FUO A;  2XSI A;  1AO6 A;  5IIH A;  4OR0 A;  5IIX A;  5DQF A;  2BXC A;  4L9K A;  4HGK A;  5IFO A;  1BJ5 A;  4K2C A;  2BXH A;  1HK1 A;  4ZBQ A;  1J78 A;  4HGM B;  4G03 A;  2BXF A;  3TDL A;  4JK4 A;  5DBY A;  2VDB A;  4G04 A;  2BXQ A;  3A73 A;  4S1Y A;  1N5U A;  1E7I A;  3V03 A;  2BXA A;  1J7E A;  4F5V A;  2I2Z A;  4N0F D;  4ZBR A;  4F5T A;  1BM0 A;  1MA9 A;  1KXP D;  2XW0 A;  2BXD A; 
#chains in the Genus database with same CATH topology
 1E7H A;  3ICX A;  1E7A A;  4PO0 A;  1KW2 A;  4TQ1 A;  5ID7 A;  1SB0 A;  2DYM A;  2XW1 A;  2OZB B;  3SIV B;  2EFH A;  2VUE A;  2Z8K A;  4LUF A;  4OTT A;  1E78 A;  2K0N A;  3FWC C;  4G01 A;  2E0X A;  1HK5 A;  2BXL A;  4J2V A;  4TQ0 A;  1TF0 A;  5HOZ A;  3GQX A;  3WHQ A;  3B9L A;  2KWF A;  3FWB C;  3LU6 A;  4C31 B;  3ECP A;  3LU8 A;  2V36 A;  3JQZ A;  4EMX A;  1KDX A;  1LNS A;  5GHK A;  2DYO A;  4K71 A;  2JUH A;  2XVW A;  1VZS A;  3V09 A;  3LU7 A;  4LA0 A;  5ID9 A;  4ZC6 A;  4ZBK A;  4ZCG A;  4E99 A;  5IJE A;  1HA2 A;  2BXO A;  2BXI A;  4N3Z A;  3GA9 L;  5D7G A;  5GIP A;  5IJF A;  4N0U D;  1NT2 B;  5B5T A;  2AJE A;  3SIU B;  1MIW A;  2EFD A;  2LQI A;  1HK3 A;  4IW2 A;  4Z9O A;  1E7B A;  3G9K D;  4BKE A;  2I30 A;  1E7E A;  2NNW A;  2EFE A;  1H9Z A;  4LB9 A;  5IIU A;  2DG5 A;  1E7F A;  3KIK A;  1GNJ A;  4L8U A;  2BXM A;  3FNM A;  4IW1 A;  2OT3 A;  3H37 A;  3V08 A;  2BXB A;  2Z8J A;  4F5U A;  1UOR A;  1E7C A;  2XVU A;  2BXP A;  1E7G A;  1H5W A;  4GG2 A;  4LUH A;  4FK5 B;  1HK2 A;  1LOT A;  2YDF A;  2Z8I A;  3WHR A;  5IJ5 A;  1MUH A;  3JRY A;  2XVQ A;  3B9M A;  2QM6 A;  2VUF A;  2BXE A;  3CX9 A;  2BXG A;  2LQH A;  3UIV A;  1HK4 A;  3BPJ A;  1MIY A;  2BXN A;  3MHH B;  4L9Q A;  1O9X A;  4OT2 A;  4ZUX V;  4Z69 A;  2LOQ A;  4FJC B;  2BX8 A;  4F5S A;  2XVV A;  4GDL B;  1BKE A;  3MHS B;  1MM8 A;  3SQJ A;  3NMU A;  2BXK A;  2E0Y A;  1GNI A;  4NAW B;  1TXU A;  2LXT A;  2GUT A;  2EFC A;  4LB2 A;  2AGH B;  5FUO A;  1MUS A;  2XSI A;  1AO6 A;  5IIH A;  4OR0 A;  5IIX A;  5DQF A;  2BXC A;  5BPK A;  4GDK B;  4L9K A;  2NQO A;  4HGK A;  1FOU A;  3W1S A;  2LXS A;  4MBE C;  5IFO A;  1BJ5 A;  4K2C A;  2BXH A;  1MIV A;  1HK1 A;  2QMC A;  4DM0 A;  4ZBQ A;  4I9O A;  3WHS A;  1J78 A;  4HGM B;  2DBW A;  4G03 A;  3NVI A;  2QHB A;  2BXF A;  4WA6 B;  3A75 A;  3TDL A;  2CKX A;  2ROH A;  3NVK A;  5GIO A;  3KJL A;  4JK4 A;  5DBY A;  2VDB A;  4FIP B;  3NVM A;  4G04 A;  3M99 C;  2BXQ A;  4M70 B;  4OTU A;  3A73 A;  2XMO A;  3H3A A;  4GDX A;  1VFI A;  4S1Y A;  1N5U A;  1E7I A;  3PLA A;  2DBU A;  2DBX A;  3V03 A;  2BXA A;  4D7X A;  5GIN A;  1J7E A;  4F5V A;  4BY9 C;  1JNB A;  2I2Z A;  2KBZ A;  4N0F D;  1IJG A;  3GQU A;  4ZBR A;  4F5T A;  4W4U B;  3VQI A;  1BM0 A;  1MA9 A;  1KXP D;  2XW0 A;  2BXD A;  4DHX B; 
#chains in the Genus database with same CATH homology
 1E7H A;  3ICX A;  1E7A A;  4PO0 A;  1KW2 A;  4TQ1 A;  5ID7 A;  2DYM A;  2XW1 A;  2OZB B;  3SIV B;  2EFH A;  2VUE A;  2Z8K A;  4LUF A;  4OTT A;  1E78 A;  3FWC C;  4G01 A;  2E0X A;  1HK5 A;  2BXL A;  4J2V A;  4TQ0 A;  1TF0 A;  5HOZ A;  3GQX A;  3WHQ A;  3B9L A;  3FWB C;  3LU6 A;  4C31 B;  3LU8 A;  2V36 A;  3JQZ A;  4EMX A;  1LNS A;  5GHK A;  2DYO A;  4K71 A;  2JUH A;  2XVW A;  1VZS A;  3V09 A;  3LU7 A;  4LA0 A;  5ID9 A;  4ZC6 A;  4ZBK A;  4ZCG A;  4E99 A;  5IJE A;  1HA2 A;  2BXO A;  2BXI A;  4N3Z A;  3GA9 L;  5D7G A;  5GIP A;  5IJF A;  4N0U D;  1NT2 B;  5B5T A;  2AJE A;  3SIU B;  1MIW A;  2EFD A;  1HK3 A;  4IW2 A;  4Z9O A;  1E7B A;  3G9K D;  4BKE A;  2I30 A;  1E7E A;  2NNW A;  2EFE A;  1H9Z A;  4LB9 A;  5IIU A;  2DG5 A;  1E7F A;  3KIK A;  1GNJ A;  4L8U A;  2BXM A;  3FNM A;  4IW1 A;  2OT3 A;  3H37 A;  3V08 A;  2BXB A;  2Z8J A;  4F5U A;  1UOR A;  1E7C A;  2XVU A;  2BXP A;  1E7G A;  1H5W A;  4GG2 A;  4LUH A;  4FK5 B;  1HK2 A;  1LOT A;  2YDF A;  2Z8I A;  3WHR A;  5IJ5 A;  3JRY A;  2XVQ A;  3B9M A;  2QM6 A;  2VUF A;  2BXE A;  3CX9 A;  2BXG A;  3UIV A;  1HK4 A;  1MIY A;  2BXN A;  3MHH B;  4L9Q A;  1O9X A;  4OT2 A;  4ZUX V;  4Z69 A;  2LOQ A;  4FJC B;  2BX8 A;  4F5S A;  2XVV A;  4GDL B;  1BKE A;  3MHS B;  3SQJ A;  3NMU A;  2BXK A;  2E0Y A;  1GNI A;  4NAW B;  1TXU A;  4LB2 A;  2EFC A;  5FUO A;  2XSI A;  1AO6 A;  5IIH A;  4OR0 A;  5IIX A;  5DQF A;  2BXC A;  5BPK A;  4GDK B;  4L9K A;  2NQO A;  4HGK A;  1FOU A;  3W1S A;  4MBE C;  5IFO A;  1BJ5 A;  4K2C A;  2BXH A;  1MIV A;  1HK1 A;  2QMC A;  4ZBQ A;  3WHS A;  1J78 A;  4HGM B;  2DBW A;  4G03 A;  3NVI A;  2QHB A;  2BXF A;  4WA6 B;  3A75 A;  3TDL A;  2CKX A;  2ROH A;  3NVK A;  5GIO A;  3KJL A;  4JK4 A;  5DBY A;  2VDB A;  4FIP B;  3NVM A;  4G04 A;  3M99 C;  2BXQ A;  4M70 B;  4OTU A;  3A73 A;  2XMO A;  3H3A A;  4GDX A;  1VFI A;  4S1Y A;  1N5U A;  1E7I A;  3PLA A;  2DBU A;  2DBX A;  3V03 A;  2BXA A;  5GIN A;  1J7E A;  4F5V A;  4BY9 C;  1JNB A;  2I2Z A;  2KBZ A;  4N0F D;  1IJG A;  3GQU A;  4ZBR A;  4F5T A;  4W4U B;  3VQI A;  1BM0 A;  1MA9 A;  1KXP D;  2XW0 A;  2BXD A;  4DHX B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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