2BYRA

Crystal structure of achbp from aplysia californica in complex with methyllycaconitine
Total Genus 53
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
53
sequence length
213
structure length
213
Chain Sequence
DDDKLHSQANLMRLKSDLFNRSPMYPGPTKDDPLTVTLGFTLQDIVKADSSTNEVDLVYYEQQRWKLNSLMWDPNEYGNITDFRTSAADIWTPDITAYSSTRPVQVLSPQIAVVTHDGSVMFIPAQRLSFMCDPTGVDSEEGATCAVKFGSWVYSGFEIDLKTDTDQVDLSSYYASSKYEILSATQTRQVQHYSCCPEPYIDVNLVVKFRERR
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structures of Aplysia Achbp Complexes with Nicotinic Agonists and Antagonists Reveal Distinctive Binding Interfaces and Conformations.
pubmed doi rcsb
molecule keywords ACETYLCHOLINE-BINDING PROTEIN
molecule tags Receptor
source organism Aplysia californica
total genus 53
structure length 213
sequence length 213
chains with identical sequence B, C, D, E, F, G, H, I, J
ec nomenclature
pdb deposition date 2005-08-03

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02931 Neur_chan_LBD Neurotransmitter-gated ion-channel ligand binding domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.70.170.10 Mainly Beta Distorted Sandwich Acetylcholine Binding Protein; Chain: A, Neurotransmitter-gated ion-channel ligand-binding domain 2byrA00
4HFHA 5AFNA 2XYSA 3C79A 2XNUA 3ZKRA 2BG9E 3U8NA 4ZRUA 3EAMA 5BW2A 3RQUA 5HEUA 3UU5A 2C9TA 2Y7YA 4QABA 4NPPA 5LG3A 4NZBA 4Z90A 3U8MA 3C84A 5HEGA 2W8FA 5J5GA 3U8KA 3TLWA 4ALXA 5BP0A 4XK9A 4TNWA 1UW6A 2YMEA 2BYRA 2WZYA 5TVCA 3JADA 3SQ9A 4EZ1A 5IUXA 5KE4A 3IGQA 4XHEA 3T4MA 2YN6A 2XQ8A 2PGZA 3UQ7A 4TWHA 4COFA 2VL0A 5FJVA 4A98A 4ILBA 4IL4A 4A97A 2Y56A 2XNVA 4Z91A 1UX2A 3WTMA 3U8LA 2PH9A 4ILAA 2YKSA 4ZZCA 5CFBA 2ZJUA 4ZJTA 2Y54A 3SQ6A 5CO5A 2X00D 3RQWA 4LMLA 3WTHA 3TLSA 2XNTA 3UUBA 3RHWA 4ZZBA 4ZK1A 2BJ0A 4B5DA 4BQTA 4F8HA 2XQ3A 2BYSA 3P50A 4AFTA 5L47A 4QAAA 2XQ6A 3RIAA 3TLVA 4HFEA 3WTLA 3UU6A 3PMZA 5HCMA 2WNJA 3SIOA 2XQ7A 4ZR6A 3JAFA 4UM3S 3UU3A 3UU4A 4UXUA 5J5FA 2W8GA 5SYOA 2XQ4A 4QH1A 4D01A 5AFLA 5AFMA 4IREA 3TLTA 5J5HA 4BFQA 2X00A 3RIFA 4IL9A 4UM3P 5AFHA 5L4HA 3WTKA 4TWDA 4ILCA 3ZDHA 4TNVA 3ZDGA 3WTJA 2XZ6A 4HFBA 5J0ZA 2Y58A 2BG9A 2YOEA 2BG9C 2ZJVA 2UZ6A 2WNCA 3EHZA 3TLUA 2XZ5A 5HCJA 5HEHA 2BR7A 1I9BA 3WTIA 2XQAA 4UM3A 2WN9A 4AFGA 4HFIA 2QC1B 3SH1A 5JMEA 3LSVA 2XYTA 4HFDA 4FRRA 4X5TA 3UU8A 5J5IA 5KZUA 5BRXA 4ZK4A 4DBMA 5AINA 5HEOA 4LMKA 4HFCA 2BYNA 2BR8A 2YMDA 5AFKA 4LMJA 4PIRA 5AFJA 3UQ4A 3WTNA 5L4EA 3WIPA 5AFMB 1UV6A 4QH5A 3P4WA 2WNLA 2BYQA 2BYPA 4UY2A 2Y57A 3EI0A 4WV9A 4AFHA 4TWFA 4UM1A 2XQ9A 4QH4A 3RI5A 5LXBA 3JAEA 4HQPA 4ZJSA 3GUAA 3PEOA 4QACA 3U8JA 3WTOA 5HEJA 2XQ5A 2BG9B
chains in the Genus database with same CATH superfamily
4HFHA 5AFNA 2XYSA 3C79A 2XNUA 3ZKRA 2BG9E 3U8NA 4ZRUA 3EAMA 5BW2A 3RQUA 5HEUA 3UU5A 2C9TA 2Y7YA 4QABA 4NPPA 5LG3A 4NZBA 4Z90A 3U8MA 3C84A 5HEGA 2W8FA 5J5GA 3U8KA 3TLWA 4ALXA 5BP0A 4XK9A 4TNWA 1UW6A 2YMEA 2BYRA 2WZYA 5TVCA 3JADA 3SQ9A 4EZ1A 5IUXA 5KE4A 3IGQA 4XHEA 3T4MA 2YN6A 2XQ8A 2PGZA 3UQ7A 4TWHA 4COFA 2VL0A 5FJVA 4A98A 4ILBA 4IL4A 4A97A 2Y56A 2XNVA 4Z91A 1UX2A 3WTMA 3U8LA 2PH9A 4ILAA 2YKSA 4ZZCA 5CFBA 2ZJUA 4ZJTA 2Y54A 3SQ6A 5CO5A 2X00D 3RQWA 4LMLA 3WTHA 3TLSA 2XNTA 3UUBA 3RHWA 4ZZBA 4ZK1A 2BJ0A 4B5DA 4BQTA 4F8HA 2XQ3A 2BYSA 3P50A 4AFTA 5L47A 4QAAA 2XQ6A 3RIAA 3TLVA 4HFEA 3WTLA 3UU6A 3PMZA 5HCMA 2WNJA 3SIOA 2XQ7A 4ZR6A 3JAFA 4UM3S 3UU3A 3UU4A 4UXUA 5J5FA 2W8GA 5SYOA 2XQ4A 4QH1A 4D01A 5AFLA 5AFMA 4IREA 3TLTA 5J5HA 4BFQA 2X00A 3RIFA 4IL9A 4UM3P 5AFHA 5L4HA 3WTKA 4TWDA 4ILCA 3ZDHA 4TNVA 3ZDGA 3WTJA 2XZ6A 4HFBA 5J0ZA 2Y58A 2BG9A 2YOEA 2BG9C 2ZJVA 2UZ6A 2WNCA 3EHZA 3TLUA 2XZ5A 5HCJA 5HEHA 2BR7A 1I9BA 3WTIA 2XQAA 4UM3A 2WN9A 4AFGA 4HFIA 2QC1B 3SH1A 5JMEA 3LSVA 2XYTA 4HFDA 4FRRA 4X5TA 3UU8A 5J5IA 5KZUA 5BRXA 4ZK4A 4DBMA 5AINA 5HEOA 4LMKA 4HFCA 2BYNA 2BR8A 2YMDA 5AFKA 4LMJA 4PIRA 5AFJA 3UQ4A 3WTNA 5L4EA 3WIPA 5AFMB 1UV6A 4QH5A 3P4WA 2WNLA 2BYQA 2BYPA 4UY2A 2Y57A 3EI0A 4WV9A 4AFHA 4TWFA 4UM1A 2XQ9A 4QH4A 3RI5A 5LXBA 3JAEA 4HQPA 4ZJSA 3GUAA 3PEOA 4QACA 3U8JA 3WTOA 5HEJA 2XQ5A 2BG9B
chains in the Genus database with same CATH topology
4HFHA 5AFNA 2XYSA 3C79A 2XNUA 3ZKRA 2BG9E 3U8NA 4ZRUA 3EAMA 5BW2A 3RQUA 5HEUA 3UU5A 2C9TA 2Y7YA 4QABA 4NPPA 5LG3A 4NZBA 4Z90A 3U8MA 3C84A 5HEGA 2W8FA 5J5GA 3U8KA 3TLWA 4ALXA 5BP0A 4XK9A 4TNWA 1UW6A 2YMEA 2BYRA 2WZYA 5TVCA 3JADA 3SQ9A 4EZ1A 5IUXA 5KE4A 3IGQA 4XHEA 3T4MA 2YN6A 2XQ8A 2PGZA 3UQ7A 4TWHA 4COFA 2VL0A 5FJVA 4A98A 4ILBA 4IL4A 4A97A 2Y56A 2XNVA 4Z91A 1UX2A 3WTMA 3U8LA 2PH9A 4ILAA 2YKSA 4ZZCA 5CFBA 2ZJUA 4ZJTA 2Y54A 3SQ6A 5CO5A 2X00D 3RQWA 4LMLA 3WTHA 3TLSA 2XNTA 3UUBA 3RHWA 4ZZBA 4ZK1A 2BJ0A 4B5DA 4BQTA 4F8HA 2XQ3A 2BYSA 3P50A 4AFTA 5L47A 4QAAA 2XQ6A 3RIAA 3TLVA 4HFEA 3WTLA 3UU6A 3PMZA 5HCMA 2WNJA 3SIOA 2XQ7A 4ZR6A 3JAFA 4UM3S 3UU3A 3UU4A 4UXUA 5J5FA 2W8GA 5SYOA 2XQ4A 4QH1A 4D01A 5AFLA 5AFMA 4IREA 3TLTA 5J5HA 4BFQA 2X00A 3RIFA 4IL9A 4UM3P 5AFHA 5L4HA 3WTKA 4TWDA 4ILCA 3ZDHA 4TNVA 3ZDGA 3WTJA 2XZ6A 4HFBA 5J0ZA 2Y58A 2BG9A 2YOEA 2BG9C 2ZJVA 2UZ6A 2WNCA 3EHZA 3TLUA 2XZ5A 5HCJA 5HEHA 2BR7A 1I9BA 3WTIA 2XQAA 4UM3A 2WN9A 4AFGA 4HFIA 2QC1B 3SH1A 5JMEA 3LSVA 2XYTA 4HFDA 4FRRA 4X5TA 3UU8A 5J5IA 5KZUA 5BRXA 4ZK4A 4DBMA 5AINA 5HEOA 4LMKA 4HFCA 2BYNA 2BR8A 2YMDA 5AFKA 4LMJA 4PIRA 5AFJA 3UQ4A 3WTNA 5L4EA 3WIPA 5AFMB 1UV6A 4QH5A 3P4WA 2WNLA 2BYQA 2BYPA 4UY2A 2Y57A 3EI0A 4WV9A 4AFHA 4TWFA 4UM1A 2XQ9A 4QH4A 3RI5A 5LXBA 3JAEA 4HQPA 4ZJSA 3GUAA 3PEOA 4QACA 3U8JA 3WTOA 5HEJA 2XQ5A 2BG9B
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4HFH A;  5AFN A;  2XYS A;  3C79 A;  2XNU A;  3ZKR A;  2BG9 E;  3U8N A;  4ZRU A;  3EAM A;  5BW2 A;  3RQU A;  5HEU A;  3UU5 A;  2C9T A;  2Y7Y A;  4QAB A;  4NPP A;  5LG3 A;  4NZB A;  4Z90 A;  3U8M A;  3C84 A;  5HEG A;  2W8F A;  5J5G A;  3U8K A;  3TLW A;  4ALX A;  5BP0 A;  4XK9 A;  4TNW A;  1UW6 A;  2YME A;  2BYR A;  2WZY A;  5TVC A;  3JAD A;  3SQ9 A;  4EZ1 A;  5IUX A;  5KE4 A;  3IGQ A;  4XHE A;  3T4M A;  2YN6 A;  2XQ8 A;  2PGZ A;  3UQ7 A;  4TWH A;  4COF A;  2VL0 A;  5FJV A;  4A98 A;  4ILB A;  4IL4 A;  4A97 A;  2Y56 A;  2XNV A;  4Z91 A;  1UX2 A;  3WTM A;  3U8L A;  2PH9 A;  4ILA A;  2YKS A;  4ZZC A;  5CFB A;  2ZJU A;  4ZJT A;  2Y54 A;  3SQ6 A;  5CO5 A;  2X00 D;  3RQW A;  4LML A;  3WTH A;  3TLS A;  2XNT A;  3UUB A;  3RHW A;  4ZZB A;  4ZK1 A;  2BJ0 A;  4B5D A;  4BQT A;  4F8H A;  2XQ3 A;  2BYS A;  3P50 A;  4AFT A;  5L47 A;  4QAA A;  2XQ6 A;  3RIA A;  3TLV A;  4HFE A;  3WTL A;  3UU6 A;  3PMZ A;  5HCM A;  2WNJ A;  3SIO A;  2XQ7 A;  4ZR6 A;  3JAF A;  4UM3 S;  3UU3 A;  3UU4 A;  4UXU A;  5J5F A;  2W8G A;  5SYO A;  2XQ4 A;  4QH1 A;  4D01 A;  5AFL A;  5AFM A;  4IRE A;  3TLT A;  5J5H A;  4BFQ A;  2X00 A;  3RIF A;  4IL9 A;  4UM3 P;  5AFH A;  5L4H A;  3WTK A;  4TWD A;  4ILC A;  3ZDH A;  4TNV A;  3ZDG A;  3WTJ A;  2XZ6 A;  4HFB A;  5J0Z A;  2Y58 A;  2BG9 A;  2YOE A;  2BG9 C;  2ZJV A;  2UZ6 A;  2WNC A;  3EHZ A;  3TLU A;  2XZ5 A;  5HCJ A;  5HEH A;  2BR7 A;  1I9B A;  3WTI A;  2XQA A;  4UM3 A;  2WN9 A;  4AFG A;  4HFI A;  2QC1 B;  3SH1 A;  5JME A;  3LSV A;  2XYT A;  4HFD A;  4FRR A;  4X5T A;  3UU8 A;  5J5I A;  5KZU A;  5BRX A;  4ZK4 A;  4DBM A;  5AIN A;  5HEO A;  4LMK A;  4HFC A;  2BYN A;  2BR8 A;  2YMD A;  5AFK A;  4LMJ A;  4PIR A;  5AFJ A;  3UQ4 A;  3WTN A;  5L4E A;  3WIP A;  5AFM B;  1UV6 A;  4QH5 A;  3P4W A;  2WNL A;  2BYQ A;  2BYP A;  4UY2 A;  2Y57 A;  3EI0 A;  4WV9 A;  4AFH A;  4TWF A;  4UM1 A;  2XQ9 A;  4QH4 A;  3RI5 A;  5LXB A;  3JAE A;  4HQP A;  4ZJS A;  3GUA A;  3PEO A;  4QAC A;  3U8J A;  3WTO A;  5HEJ A;  2XQ5 A;  2BG9 B; 
#chains in the Genus database with same CATH topology
 4HFH A;  5AFN A;  2XYS A;  3C79 A;  2XNU A;  3ZKR A;  2BG9 E;  3U8N A;  4ZRU A;  3EAM A;  5BW2 A;  3RQU A;  5HEU A;  3UU5 A;  2C9T A;  2Y7Y A;  4QAB A;  4NPP A;  5LG3 A;  4NZB A;  4Z90 A;  3U8M A;  3C84 A;  5HEG A;  2W8F A;  5J5G A;  3U8K A;  3TLW A;  4ALX A;  5BP0 A;  4XK9 A;  4TNW A;  1UW6 A;  2YME A;  2BYR A;  2WZY A;  5TVC A;  3JAD A;  3SQ9 A;  4EZ1 A;  5IUX A;  5KE4 A;  3IGQ A;  4XHE A;  3T4M A;  2YN6 A;  2XQ8 A;  2PGZ A;  3UQ7 A;  4TWH A;  4COF A;  2VL0 A;  5FJV A;  4A98 A;  4ILB A;  4IL4 A;  4A97 A;  2Y56 A;  2XNV A;  4Z91 A;  1UX2 A;  3WTM A;  3U8L A;  2PH9 A;  4ILA A;  2YKS A;  4ZZC A;  5CFB A;  2ZJU A;  4ZJT A;  2Y54 A;  3SQ6 A;  5CO5 A;  2X00 D;  3RQW A;  4LML A;  3WTH A;  3TLS A;  2XNT A;  3UUB A;  3RHW A;  4ZZB A;  4ZK1 A;  2BJ0 A;  4B5D A;  4BQT A;  4F8H A;  2XQ3 A;  2BYS A;  3P50 A;  4AFT A;  5L47 A;  4QAA A;  2XQ6 A;  3RIA A;  3TLV A;  4HFE A;  3WTL A;  3UU6 A;  3PMZ A;  5HCM A;  2WNJ A;  3SIO A;  2XQ7 A;  4ZR6 A;  3JAF A;  4UM3 S;  3UU3 A;  3UU4 A;  4UXU A;  5J5F A;  2W8G A;  5SYO A;  2XQ4 A;  4QH1 A;  4D01 A;  5AFL A;  5AFM A;  4IRE A;  3TLT A;  5J5H A;  4BFQ A;  2X00 A;  3RIF A;  4IL9 A;  4UM3 P;  5AFH A;  5L4H A;  3WTK A;  4TWD A;  4ILC A;  3ZDH A;  4TNV A;  3ZDG A;  3WTJ A;  2XZ6 A;  4HFB A;  5J0Z A;  2Y58 A;  2BG9 A;  2YOE A;  2BG9 C;  2ZJV A;  2UZ6 A;  2WNC A;  3EHZ A;  3TLU A;  2XZ5 A;  5HCJ A;  5HEH A;  2BR7 A;  1I9B A;  3WTI A;  2XQA A;  4UM3 A;  2WN9 A;  4AFG A;  4HFI A;  2QC1 B;  3SH1 A;  5JME A;  3LSV A;  2XYT A;  4HFD A;  4FRR A;  4X5T A;  3UU8 A;  5J5I A;  5KZU A;  5BRX A;  4ZK4 A;  4DBM A;  5AIN A;  5HEO A;  4LMK A;  4HFC A;  2BYN A;  2BR8 A;  2YMD A;  5AFK A;  4LMJ A;  4PIR A;  5AFJ A;  3UQ4 A;  3WTN A;  5L4E A;  3WIP A;  5AFM B;  1UV6 A;  4QH5 A;  3P4W A;  2WNL A;  2BYQ A;  2BYP A;  4UY2 A;  2Y57 A;  3EI0 A;  4WV9 A;  4AFH A;  4TWF A;  4UM1 A;  2XQ9 A;  4QH4 A;  3RI5 A;  5LXB A;  3JAE A;  4HQP A;  4ZJS A;  3GUA A;  3PEO A;  4QAC A;  3U8J A;  3WTO A;  5HEJ A;  2XQ5 A;  2BG9 B; 
#chains in the Genus database with same CATH homology
 4HFH A;  5AFN A;  2XYS A;  3C79 A;  2XNU A;  3ZKR A;  2BG9 E;  3U8N A;  4ZRU A;  3EAM A;  5BW2 A;  3RQU A;  5HEU A;  3UU5 A;  2C9T A;  2Y7Y A;  4QAB A;  4NPP A;  5LG3 A;  4NZB A;  4Z90 A;  3U8M A;  3C84 A;  5HEG A;  2W8F A;  5J5G A;  3U8K A;  3TLW A;  4ALX A;  5BP0 A;  4XK9 A;  4TNW A;  1UW6 A;  2YME A;  2BYR A;  2WZY A;  5TVC A;  3JAD A;  3SQ9 A;  4EZ1 A;  5IUX A;  5KE4 A;  3IGQ A;  4XHE A;  3T4M A;  2YN6 A;  2XQ8 A;  2PGZ A;  3UQ7 A;  4TWH A;  4COF A;  2VL0 A;  5FJV A;  4A98 A;  4ILB A;  4IL4 A;  4A97 A;  2Y56 A;  2XNV A;  4Z91 A;  1UX2 A;  3WTM A;  3U8L A;  2PH9 A;  4ILA A;  2YKS A;  4ZZC A;  5CFB A;  2ZJU A;  4ZJT A;  2Y54 A;  3SQ6 A;  5CO5 A;  2X00 D;  3RQW A;  4LML A;  3WTH A;  3TLS A;  2XNT A;  3UUB A;  3RHW A;  4ZZB A;  4ZK1 A;  2BJ0 A;  4B5D A;  4BQT A;  4F8H A;  2XQ3 A;  2BYS A;  3P50 A;  4AFT A;  5L47 A;  4QAA A;  2XQ6 A;  3RIA A;  3TLV A;  4HFE A;  3WTL A;  3UU6 A;  3PMZ A;  5HCM A;  2WNJ A;  3SIO A;  2XQ7 A;  4ZR6 A;  3JAF A;  4UM3 S;  3UU3 A;  3UU4 A;  4UXU A;  5J5F A;  2W8G A;  5SYO A;  2XQ4 A;  4QH1 A;  4D01 A;  5AFL A;  5AFM A;  4IRE A;  3TLT A;  5J5H A;  4BFQ A;  2X00 A;  3RIF A;  4IL9 A;  4UM3 P;  5AFH A;  5L4H A;  3WTK A;  4TWD A;  4ILC A;  3ZDH A;  4TNV A;  3ZDG A;  3WTJ A;  2XZ6 A;  4HFB A;  5J0Z A;  2Y58 A;  2BG9 A;  2YOE A;  2BG9 C;  2ZJV A;  2UZ6 A;  2WNC A;  3EHZ A;  3TLU A;  2XZ5 A;  5HCJ A;  5HEH A;  2BR7 A;  1I9B A;  3WTI A;  2XQA A;  4UM3 A;  2WN9 A;  4AFG A;  4HFI A;  2QC1 B;  3SH1 A;  5JME A;  3LSV A;  2XYT A;  4HFD A;  4FRR A;  4X5T A;  3UU8 A;  5J5I A;  5KZU A;  5BRX A;  4ZK4 A;  4DBM A;  5AIN A;  5HEO A;  4LMK A;  4HFC A;  2BYN A;  2BR8 A;  2YMD A;  5AFK A;  4LMJ A;  4PIR A;  5AFJ A;  3UQ4 A;  3WTN A;  5L4E A;  3WIP A;  5AFM B;  1UV6 A;  4QH5 A;  3P4W A;  2WNL A;  2BYQ A;  2BYP A;  4UY2 A;  2Y57 A;  3EI0 A;  4WV9 A;  4AFH A;  4TWF A;  4UM1 A;  2XQ9 A;  4QH4 A;  3RI5 A;  5LXB A;  3JAE A;  4HQP A;  4ZJS A;  3GUA A;  3PEO A;  4QAC A;  3U8J A;  3WTO A;  5HEJ A;  2XQ5 A;  2BG9 B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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