2C1NA

Molecular basis for the recognition of phosphorylated and phosphoacetylated histone h3 by 14-3-3
Total Genus 94
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
94
sequence length
230
structure length
225
Chain Sequence
MDKNELVQKAKLAEQAERYDDMAACMKSVTEQGAELSNEERNLLSVAYKNVVGARRSSWRVVSSIEQKTEGAEKKQQMAREYREKIETELRDICNDVLSLLEKFLIPNASQAESKVFYLKMKGDYYRYLAEVAKGIVDQSQQAYQEAFEISKKEMQPTHPIRLGLALNFSVFYYEILNSPEKACSLAKTAFDEAIAELDTLSEESYKDSTLIMQLLRDNLTLWTS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Molecular Basis for the Recognition of Phosphorylated and Phosphoacetylated Histone H3 by 14-3-3.
pubmed doi rcsb
molecule tags Signaling protein
source organism Homo sapiens
molecule keywords 14-3-3 PROTEIN ZETA/DELTA
total genus 94
structure length 225
sequence length 230
chains with identical sequence B
ec nomenclature
pdb deposition date 2005-09-16

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00244 14-3-3 14-3-3 protein
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.190.20 Mainly Alpha Up-down Bundle Delta-Endotoxin; domain 1 14-3-3 domain 2c1nA00
3SP5A 3P1QA 3P1OA 5BTVA 1A38A 2BR9A 1QJAA 2O02A 2BQ0A 4DHSA 5HF3A 4IEAA 3IQVA 4Y3BA 3P1RA 3UALA 3SMOA 4DHRA 5J31A 1IB1A 3CU8A 4DHNA 4ZQ0A 1YWTA 4DHTA 3LW1A 5F74A 4E2EA 4DHUA 2C63A 4FL5A 3UZDA 4ZDRA 1A4OA 3RDHA 3NKXA 3UX0A 1O9FA 3M51A 3AXYC 4DAUA 3T0LA 4FJ3A 4J6SA 3U9XA 3SMKA 2O8PA 4DATA 3P1SA 4DHPA 4Y5IA 4JC3A 5LU2A 3O8IA 5LHOA 2C1NA 3SMNA 5D2DA 5EXAA 4WRQA 2NPMA 4DHOA 3MHRA 1YZ5A 2BTPA 2O98A 3P1NA 3P1PA 4IHLA 5D3FA 3SPRA 3IQJA 2V7DA 3IQUA 5LX2A 4BG6A 4N7YA 1O9EA 5BY9A 3E6YA 3SMMA 4O46A 4GNTA 1O9CA 4DHQA 5IQPA 4JDDA 5LU1A 3EFZA 3T0MA 2WH0A 2C1JA 4DX0A 4DNKA 4FR3A 2C74A 1QJBA 5D3EA 4F7RA 3SMLA 3UBWA 1O9DA 4HKCA 2C23A 4N84A 2B05A 1A37A 4DHMA 5EWZA 3M50A 5LVZA 4N7GA 4QLIA 4Y32A
chains in the Genus database with same CATH superfamily
3SP5A 3P1QA 4ARXA 3P1OA 5BTVA 1A38A 2BR9A 1QJAA 3ZHEB 2O02A 2BQ0A 4DHSA 5HF3A 4IEAA 4QX1A 3IQVA 1S2XA 4Y3BA 3P1RA 3UALA 3SMOA 4DHRA 5J31A 3CQGA 1IB1A 3CU8A 1I5PA 4DHNA 4ZQ0A 1YWTA 4DHTA 3LW1A 5F74A 4E2EA 4DHUA 2C63A 4ARYA 1DLCA 4FL5A 3UZDA 4ZDRA 1A4OA 3RDHA 3NKXA 3UX0A 1O9FA 4MOAA 3M51A 3AXYC 4DAUA 3T0LA 4FJ3A 4J6SA 3U9XA 3SMKA 2O8PA 4DATA 1W99A 3X0UA 3P1SA 4DHPA 4D8MA 4Y5IA 4JC3A 5LU2A 3O8IA 5LHOA 2C9KA 2C1NA 3SMNA 5D2DA 5EXAA 4WRQA 2NPMA 4QX2A 4DHOA 3MHRA 4W8JA 3CQCA 4QX0A 1YZ5A 2BTPA 2O98A 3P1NA 3P1PA 4IHLA 3EB7A 5D3FA 3SPRA 3IQJA 2V7DA 3IQUA 5LX2A 4BG6A 1JI6A 4N7YA 1O9EA 5BY9A 3E6YA 3SMMA 1CIYA 4O46A 4GNTA 1O9CA 4DHQA 5IQPA 4JDDA 5LU1A 3EFZA 3T0MA 2WH0A 2C1JA 4DX0A 4DNKA 4FR3A 2C74A 4QX3A 1QJBA 5D3EA 4F7RA 3SMLA 3UBWA 1O9DA 4HKCA 2C23A 4N84A 2B05A 1A37A 4DHMA 5EWZA 3M50A 5LVZA 1URJA 4N7GA 4QLIA 3I4RA 4Y32A
chains in the Genus database with same CATH topology
3SP5A 3P1QA 3P1OA 5BTVA 1A38A 2BR9A 1QJAA 2O02A 2BQ0A 4DHSA 5HF3A 4IEAA 3IQVA 4Y3BA 3P1RA 3UALA 3SMOA 4DHRA 5J31A 1IB1A 3CU8A 4DHNA 4ZQ0A 1YWTA 4DHTA 3LW1A 5F74A 4E2EA 4DHUA 2C63A 4FL5A 3UZDA 4ZDRA 1A4OA 3RDHA 3NKXA 3UX0A 1O9FA 3M51A 3AXYC 4DAUA 3T0LA 4FJ3A 4J6SA 3U9XA 3SMKA 2O8PA 4DATA 3P1SA 4DHPA 4Y5IA 4JC3A 5LU2A 3O8IA 5LHOA 2C1NA 3SMNA 5D2DA 5EXAA 4WRQA 2NPMA 4DHOA 3MHRA 1YZ5A 2BTPA 2O98A 3P1NA 3P1PA 4IHLA 5D3FA 3SPRA 3IQJA 2V7DA 3IQUA 5LX2A 4BG6A 4N7YA 1O9EA 5BY9A 3E6YA 3SMMA 4O46A 4GNTA 1O9CA 4DHQA 5IQPA 4JDDA 5LU1A 3EFZA 3T0MA 2WH0A 2C1JA 4DX0A 4DNKA 4FR3A 2C74A 1QJBA 5D3EA 4F7RA 3SMLA 3UBWA 1O9DA 4HKCA 2C23A 4N84A 2B05A 1A37A 4DHMA 5EWZA 3M50A 5LVZA 4N7GA 4QLIA 4Y32A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3SP5 A;  3P1Q A;  3P1O A;  5BTV A;  1A38 A;  2BR9 A;  1QJA A;  2O02 A;  2BQ0 A;  4DHS A;  5HF3 A;  4IEA A;  3IQV A;  4Y3B A;  3P1R A;  3UAL A;  3SMO A;  4DHR A;  5J31 A;  1IB1 A;  3CU8 A;  4DHN A;  4ZQ0 A;  1YWT A;  4DHT A;  3LW1 A;  5F74 A;  4E2E A;  4DHU A;  2C63 A;  4FL5 A;  3UZD A;  4ZDR A;  1A4O A;  3RDH A;  3NKX A;  3UX0 A;  1O9F A;  3M51 A;  3AXY C;  4DAU A;  3T0L A;  4FJ3 A;  4J6S A;  3U9X A;  3SMK A;  2O8P A;  4DAT A;  3P1S A;  4DHP A;  4Y5I A;  4JC3 A;  5LU2 A;  3O8I A;  5LHO A;  2C1N A;  3SMN A;  5D2D A;  5EXA A;  4WRQ A;  2NPM A;  4DHO A;  3MHR A;  1YZ5 A;  2BTP A;  2O98 A;  3P1N A;  3P1P A;  4IHL A;  5D3F A;  3SPR A;  3IQJ A;  2V7D A;  3IQU A;  5LX2 A;  4BG6 A;  4N7Y A;  1O9E A;  5BY9 A;  3E6Y A;  3SMM A;  4O46 A;  4GNT A;  1O9C A;  4DHQ A;  5IQP A;  4JDD A;  5LU1 A;  3EFZ A;  3T0M A;  2WH0 A;  2C1J A;  4DX0 A;  4DNK A;  4FR3 A;  2C74 A;  1QJB A;  5D3E A;  4F7R A;  3SML A;  3UBW A;  1O9D A;  4HKC A;  2C23 A;  4N84 A;  2B05 A;  1A37 A;  4DHM A;  5EWZ A;  3M50 A;  5LVZ A;  4N7G A;  4QLI A;  4Y32 A; 
#chains in the Genus database with same CATH topology
 3SP5 A;  3P1Q A;  4ARX A;  3P1O A;  5BTV A;  1A38 A;  2BR9 A;  1QJA A;  3ZHE B;  2O02 A;  2BQ0 A;  4DHS A;  5HF3 A;  4IEA A;  4QX1 A;  3IQV A;  1S2X A;  4Y3B A;  3P1R A;  3UAL A;  3SMO A;  4DHR A;  5J31 A;  3CQG A;  1IB1 A;  3CU8 A;  1I5P A;  4DHN A;  4ZQ0 A;  1YWT A;  4DHT A;  3LW1 A;  5F74 A;  4E2E A;  4DHU A;  2C63 A;  4ARY A;  1DLC A;  4FL5 A;  3UZD A;  4ZDR A;  1A4O A;  3RDH A;  3NKX A;  3UX0 A;  1O9F A;  4MOA A;  3M51 A;  3AXY C;  4DAU A;  3T0L A;  4FJ3 A;  4J6S A;  3U9X A;  3SMK A;  2O8P A;  4DAT A;  1W99 A;  3X0U A;  3P1S A;  4DHP A;  4D8M A;  4Y5I A;  4JC3 A;  5LU2 A;  3O8I A;  5LHO A;  2C9K A;  2C1N A;  3SMN A;  5D2D A;  5EXA A;  4WRQ A;  2NPM A;  4QX2 A;  4DHO A;  3MHR A;  4W8J A;  3CQC A;  4QX0 A;  1YZ5 A;  2BTP A;  2O98 A;  3P1N A;  3P1P A;  4IHL A;  3EB7 A;  5D3F A;  3SPR A;  3IQJ A;  2V7D A;  3IQU A;  5LX2 A;  4BG6 A;  1JI6 A;  4N7Y A;  1O9E A;  5BY9 A;  3E6Y A;  3SMM A;  1CIY A;  4O46 A;  4GNT A;  1O9C A;  4DHQ A;  5IQP A;  4JDD A;  5LU1 A;  3EFZ A;  3T0M A;  2WH0 A;  2C1J A;  4DX0 A;  4DNK A;  4FR3 A;  2C74 A;  4QX3 A;  1QJB A;  5D3E A;  4F7R A;  3SML A;  3UBW A;  1O9D A;  4HKC A;  2C23 A;  4N84 A;  2B05 A;  1A37 A;  4DHM A;  5EWZ A;  3M50 A;  5LVZ A;  1URJ A;  4N7G A;  4QLI A;  3I4R A;  4Y32 A; 
#chains in the Genus database with same CATH homology
 3SP5 A;  3P1Q A;  3P1O A;  5BTV A;  1A38 A;  2BR9 A;  1QJA A;  2O02 A;  2BQ0 A;  4DHS A;  5HF3 A;  4IEA A;  3IQV A;  4Y3B A;  3P1R A;  3UAL A;  3SMO A;  4DHR A;  5J31 A;  1IB1 A;  3CU8 A;  4DHN A;  4ZQ0 A;  1YWT A;  4DHT A;  3LW1 A;  5F74 A;  4E2E A;  4DHU A;  2C63 A;  4FL5 A;  3UZD A;  4ZDR A;  1A4O A;  3RDH A;  3NKX A;  3UX0 A;  1O9F A;  3M51 A;  3AXY C;  4DAU A;  3T0L A;  4FJ3 A;  4J6S A;  3U9X A;  3SMK A;  2O8P A;  4DAT A;  3P1S A;  4DHP A;  4Y5I A;  4JC3 A;  5LU2 A;  3O8I A;  5LHO A;  2C1N A;  3SMN A;  5D2D A;  5EXA A;  4WRQ A;  2NPM A;  4DHO A;  3MHR A;  1YZ5 A;  2BTP A;  2O98 A;  3P1N A;  3P1P A;  4IHL A;  5D3F A;  3SPR A;  3IQJ A;  2V7D A;  3IQU A;  5LX2 A;  4BG6 A;  4N7Y A;  1O9E A;  5BY9 A;  3E6Y A;  3SMM A;  4O46 A;  4GNT A;  1O9C A;  4DHQ A;  5IQP A;  4JDD A;  5LU1 A;  3EFZ A;  3T0M A;  2WH0 A;  2C1J A;  4DX0 A;  4DNK A;  4FR3 A;  2C74 A;  1QJB A;  5D3E A;  4F7R A;  3SML A;  3UBW A;  1O9D A;  4HKC A;  2C23 A;  4N84 A;  2B05 A;  1A37 A;  4DHM A;  5EWZ A;  3M50 A;  5LVZ A;  4N7G A;  4QLI A;  4Y32 A; 
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similar chains in the Genus database (?% sequence similarity)
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