2C5XB

Differential binding of inhibitors to active and inactive cdk2 provides insights for drug design
Total Genus 86
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
86
sequence length
258
structure length
258
Chain Sequence
VPDYHEDIHTYLREMEVKCKPKVGYMKKQPDITNSMRAILVDWLVEVGEEYKLQNETLHLAVNYIDRFLSSMSVLRGKLQLVGTAAMLLASKFEEIYPPEVAEFVYITDDTYTKKQVLRMEHLVLKVLTFDLAAPTVNQFLTQYFLHQQPANCKVESLAMFLGELSLIDADPYLKYLPSVIAGAAFHLALYTVTGQSWPESLIRKTGYTLESLKPCLMDLHQTYLKAPQHAQQSIREKYKNSKYHGVSLLNPPETLNL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Differential Binding of Inhibitors to Active and Inactive Cdk2 Provides Insights for Drug Design.
pubmed doi rcsb
molecule tags Transferase/inhibitor
source organism Homo sapiens
molecule keywords CELL DIVISION PROTEIN KINASE 2
total genus 86
structure length 258
sequence length 258
chains with identical sequence D
ec nomenclature
pdb deposition date 2005-11-03

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF00134 Cyclin_N Cyclin, N-terminal domain
B PF02984 Cyclin_C Cyclin, C-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.472.10 Mainly Alpha Orthogonal Bundle Cyclin A; domain 1 Cyclin-like 2c5xB01
1.10.472.10 Mainly Alpha Orthogonal Bundle Cyclin A; domain 1 Cyclin-like 2c5xB02
2WXVB 4Y72B 4ELLA 5I5ZB 2B9RA 5HVYB 2WMAB 1N4MA 2WFYB 1G3NC 2UUEB 4CXAB 5L2WB 4EOJB 1GUXA 2C5VB 5HNBB 1JSUB 1OL1B 3M03A 4BCGB 4CFVB 4RODA 3QHRB 4CFWB 5ICPB 3DDQB 2W9FA 5CEIB 5HBEB 1E9HB 5HQ0B 2IW9B 4F7LB 3O0GD 1H1PB 2PHGA 4BCJB 4ROCA 1H4LD 1URCB 2EUFA 2R7GA 2I40B 1OI9B 1OIUB 4EOLB 1VYWB 1PKDB 3BLRB 1FINB 2WPAB 4EOOB 4F7NB 1JSTB 4FX3B 4F6UB 2G9XB 4EOSB 2W99A 1UNHD 1H24B 4BCQB 4BCOB 1OGUB 3DDPB 4YOOA 1OL2B 3EIDB 2BPMB 1W98B 1QMZB 3MI9B 4OGRB 3K7AM 2WIHB 2X1NB 3BHTB 4EOPB 2WHBB 2C5OB 4EC9B 2PMIB 2I53A 1UNLD 1BU2A 4BCMD 4EOQB 3G33B 4BCNB 5IDNB 1H28B 1H1QB 1ZP2A 4EOKB 4YOZA 2PK9B 1KXUA 1XO2A 3MIAB 4EORB 1OKWB 4EOIB 4CFUB 2C6TB 1O9KB 4ROEA 4KRDB 5ACBA 5CYIB 4TTHA 2CCIB 4CFXB 5LMKB 1JOWA 4BCKB 4BCFB 3DOGB 3QHWB 5EFQB 2PK2A 2BKZB 1H1SB 1H27B 2UZEB 2IW6B 3EJ1B 1FVVB 4ELJA 2QDJA 4EOMB 2CJMB 1GH6B 2WMBB 4I3ZB 1C9BA 4BCPB 1JKWA 1OIYB 3MY1B 4CFUD 2W96A 4EC8B 1AISB 2CCHB 4IMYB 4BCQD 1F5QB 2V22B 3TNIB 3BLHB 3EOCB 1H26B 3TNWB 3POMA 4KRCB 4EONB 2C5XB 4F7SB 1D3UB 5IF1B 5IDPB 1H1RB 1O9KA 2WEVB 4OR5B 4BCIB 5HBJB 4F6SB 1GUXB 4YOSA 5BNJB 3LQ5B 4NSTB 5FGKB 3TNHB 4UN0A 4F70B 3BLQB 3RGFB 2C5NB 4F6WB 1H25B 3BHUB 1AD6A 3H4CA 4BCND 3F5XB 2WIPB 2IW8B 4G6LB 5HBHB 4CFNB 4CRLB 1TFBA 1UNGD 3TN8B 2IVXA 2UZDB 1VINA 4BCMB 1GY3B 4YC3B 2C4GB 4CFMB 2JGZB 4F7JB 2F2CA 2UZLB 3MY5B 2UZBB 1OKVB 2W9ZA 3BHVB 2W2HA 5LQFB 4BCHB 1VOLA 1P5EB 4II5B
chains in the Genus database with same CATH superfamily
5HVYB 3KHIA 2DXBB 4OB1B 1G3NC 3QYHB 4EOJB 1E7PA 1JSUB 3M03A 3QZ5B 4CFWB 5CEIB 3O0GD 1H1PB 2EUFA 4HNVA 4ZGDB 1FINB 4FX3B 4EOSB 3DDPB 1OL2B 2KR6A 3BHTB 2DD4B 2WHBB 4HLQA 1BU2A 4BCNB 5IDNB 2PJQA 3DTOA 4EOKB 1AHJB 2ZZDB 4NC6A 1KXUA 1XO2A 3MIAB 4EORB 4EOIB 1O9KB 4ROEA 5CYIB 4TTHA 5LMKB 2QDYB 4BCKB 3PO3S 1H1SB 1H27B 2UZEB 4ELJA 2QDJA 2CZ0B 2WMBB 3X25B 2D0QB 4I3ZB 5DQVA 1OIYB 4BCQD 4AKIA 3TNWB 3VKGA 4KRCB 4EONB 2QF7A 1H1RB 4BCIB 3WVEB 4NSTB 2ZPBB 1UGQB 4HNTA 4UN0A 4CRLB 2WIPB 3DJBA 2QQ8A 2UZDB 4ZGEB 4YC3B 4JX5A 2F2CA 3MY5B 2CZ7B 3VYHB 2BS3A 4OB3B 2IN3A 4F7SB 4II5B 4Y72B 4OB2B 4BBSM 3QYGB 2WFYB 4CXAB 3TW6A 1OL1B 4CFVB 1E9HB 4JX4A 4BCJB 1H4LD 2R7GA 4EOLB 3A8OB 4EOOB 3HBLA 1H24B 3DL1A 2WJ9A 4YOOA 2BPMB 1QMZB 4OGRB 2QFZA 2C5OB 1UNLD 1UGRB 1H28B 1H1QB 3BG3A 4YOZA 2PK9B 2DMEA 2ZPHB 3TW7A 4MFEA 4JX6A 4BBRM 2CCIB 3DOGB 3QHWB 5EFQB 2BKZB 2IW6B 4EOMB 2CJMB 1GH6B 2DXCB 3MY1B 3X20B 2V22B 3TNIB 3BLHB 3EOCB 1H26B 1V29B 5IF1B 4M6VA 4YOSA 4BY1X 1UGSB 5FGKB 3TNHB 4F70B 3BHUB 4BCND 2IW8B 1UNGD 3A8MB 1VINA 4BCMB 1GY3B 1OKVB 4BCHB 4ELLA 2B9RA 2WMAB 1N4MA 2UUEB 5L2WB 1GUXA 2C5VB 5HNBB 4BCGB 4MFDA 3DDQB 2W9FA 5HBEB 2G77A 5HQ0B 4F7LB 2PHGA 2DD5B 1OIUB 3X26B 3BLRB 4HL4A 2WPAB 3A8HB 1JSTB 2G9XB 4ZGJB 4BCOB 1OGUB 1W98B 3MI9B 3B57A 2WIHB 4EOPB 2I53A 4HNUA 3A8LB 4EOQB 3QWLA 2ZPEB 3BG5A 2LW4A 4CFUB 3GTMS 4CFXB 2PK2A 3EJ1B 1FVVB 3HB9A 3A8GB 4LOCA 4BCPB 1JKWA 4OB0B 2AHJB 2W96A 4CFUD 2ZCFB 2CCHB 4IMYB 2ZPIB 4AKGA 2CYZB 1D3UB 1O9KA 5BNJB 2ZPGB 5IHYA 2CZ6B 4AI6A 3BLQB 3RGFB 2C5NB 4AKHA 1AD6A 3H4CA 5HBHB 4CFNB 1TFBA 5EJCA 2IVXA 2KMGA 2UZBB 2W2HA 2WXVB 5I5ZB 1QLBA 3QXEB 4RODA 3QHRB 5ICPB 3HO8A 4BXXX 2IW9B 4ROCA 3X28B 1URCB 2I40B 1OI9B 1VYWB 4FM4B 4Z6YA 1PKDB 4F7NB 4F6UB 1FKMA 4MIMA 2W99A 1UNHD 4BCQB 3WVDB 3EIDB 3QYBA 1IREB 3HZJA 3K7AM 2X1NB 2BS4A 4EC9B 2PMIB 4BCMD 3G33B 1ZP2A 2BS2A 2DPPB 1OKWB 2C6TB 4BY7X 3VYGB 2ZPFB 4KRDB 5ACBA 1JOWA 5DQWA 4BCFB 3HHTB 1ENWA 2CZ1B 3QYEA 1TD6A 2QGSA 3VKHA 1C9BA 4EC8B 1AISB 1F5QB 3POMA 3QZ9B 2C5XB 1UGPB 4QSHA 5IDPB 2WEVB 4OR5B 5HBJB 4F6SB 1GUXB 3LQ5B 4F6WB 3NDQA 1H25B 3BG9A 3F5XB 4G6LB 3TN8B 4CFMB 2C4GB 2JGZB 4F7JB 2UZLB 2W9ZA 3BHVB 3X24B 5LQFB 1VOLA 1P5EB
chains in the Genus database with same CATH topology
2WXVB 4Y72B 4ELLA 5I5ZB 2B9RA 5HVYB 2WMAB 1N4MA 2WFYB 1G3NC 2UUEB 4CXAB 5L2WB 4EOJB 1GUXA 2C5VB 5HNBB 1JSUB 1OL1B 3M03A 4BCGB 4CFVB 4RODA 3QHRB 4CFWB 5ICPB 3DDQB 2W9FA 5CEIB 5HBEB 1E9HB 5HQ0B 2IW9B 4F7LB 3O0GD 1H1PB 2PHGA 4BCJB 4ROCA 1H4LD 1URCB 2EUFA 2R7GA 2I40B 1OI9B 1OIUB 4EOLB 1VYWB 1PKDB 3BLRB 1FINB 2WPAB 4EOOB 4F7NB 1JSTB 4FX3B 4F6UB 2G9XB 4EOSB 2W99A 1UNHD 1H24B 4BCQB 4BCOB 1OGUB 3DDPB 4YOOA 1OL2B 3EIDB 2BPMB 1W98B 1QMZB 3MI9B 4OGRB 3K7AM 2WIHB 2X1NB 3BHTB 4EOPB 2WHBB 2C5OB 4EC9B 2PMIB 2I53A 1UNLD 1BU2A 4BCMD 4EOQB 3G33B 4BCNB 5IDNB 1H28B 1H1QB 1ZP2A 4EOKB 4YOZA 2PK9B 1KXUA 1XO2A 3MIAB 4EORB 1OKWB 4EOIB 4CFUB 2C6TB 1O9KB 4ROEA 4KRDB 5ACBA 5CYIB 4TTHA 2CCIB 4CFXB 5LMKB 1JOWA 4BCKB 4BCFB 3DOGB 3QHWB 5EFQB 2PK2A 2BKZB 1H1SB 1H27B 2UZEB 2IW6B 3EJ1B 1FVVB 4ELJA 2QDJA 4EOMB 2CJMB 1GH6B 2WMBB 4I3ZB 1C9BA 4BCPB 1JKWA 1OIYB 3MY1B 4CFUD 2W96A 4EC8B 1AISB 2CCHB 4IMYB 4BCQD 1F5QB 2V22B 3TNIB 3BLHB 3EOCB 1H26B 3TNWB 3POMA 4KRCB 4EONB 2C5XB 4F7SB 1D3UB 5IF1B 5IDPB 1H1RB 1O9KA 2WEVB 4OR5B 4BCIB 5HBJB 4F6SB 1GUXB 4YOSA 5BNJB 3LQ5B 4NSTB 5FGKB 3TNHB 4UN0A 4F70B 3BLQB 3RGFB 2C5NB 4F6WB 1H25B 3BHUB 1AD6A 3H4CA 4BCND 3F5XB 2WIPB 2IW8B 4G6LB 5HBHB 4CFNB 4CRLB 1TFBA 1UNGD 3TN8B 2IVXA 2UZDB 1VINA 4BCMB 1GY3B 4YC3B 2C4GB 4CFMB 2JGZB 4F7JB 2F2CA 2UZLB 3MY5B 2UZBB 1OKVB 2W9ZA 3BHVB 2W2HA 5LQFB 4BCHB 1VOLA 1P5EB 4II5B
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2WXV B;  4Y72 B;  4ELL A;  5I5Z B;  2B9R A;  5HVY B;  2WMA B;  1N4M A;  2WFY B;  1G3N C;  2UUE B;  4CXA B;  5L2W B;  4EOJ B;  1GUX A;  2C5V B;  5HNB B;  1JSU B;  1OL1 B;  3M03 A;  4BCG B;  4CFV B;  4ROD A;  3QHR B;  4CFW B;  5ICP B;  3DDQ B;  2W9F A;  5CEI B;  5HBE B;  1E9H B;  5HQ0 B;  2IW9 B;  4F7L B;  3O0G D;  1H1P B;  2PHG A;  4BCJ B;  4ROC A;  1H4L D;  1URC B;  2EUF A;  2R7G A;  2I40 B;  1OI9 B;  1OIU B;  4EOL B;  1VYW B;  1PKD B;  3BLR B;  1FIN B;  2WPA B;  4EOO B;  4F7N B;  1JST B;  4FX3 B;  4F6U B;  2G9X B;  4EOS B;  2W99 A;  1UNH D;  1H24 B;  4BCQ B;  4BCO B;  1OGU B;  3DDP B;  4YOO A;  1OL2 B;  3EID B;  2BPM B;  1W98 B;  1QMZ B;  3MI9 B;  4OGR B;  3K7A M;  2WIH B;  2X1N B;  3BHT B;  4EOP B;  2WHB B;  2C5O B;  4EC9 B;  2PMI B;  2I53 A;  1UNL D;  1BU2 A;  4BCM D;  4EOQ B;  3G33 B;  4BCN B;  5IDN B;  1H28 B;  1H1Q B;  1ZP2 A;  4EOK B;  4YOZ A;  2PK9 B;  1KXU A;  1XO2 A;  3MIA B;  4EOR B;  1OKW B;  4EOI B;  4CFU B;  2C6T B;  1O9K B;  4ROE A;  4KRD B;  5ACB A;  5CYI B;  4TTH A;  2CCI B;  4CFX B;  5LMK B;  1JOW A;  4BCK B;  4BCF B;  3DOG B;  3QHW B;  5EFQ B;  2PK2 A;  2BKZ B;  1H1S B;  1H27 B;  2UZE B;  2IW6 B;  3EJ1 B;  1FVV B;  4ELJ A;  2QDJ A;  4EOM B;  2CJM B;  1GH6 B;  2WMB B;  4I3Z B;  1C9B A;  4BCP B;  1JKW A;  1OIY B;  3MY1 B;  4CFU D;  2W96 A;  4EC8 B;  1AIS B;  2CCH B;  4IMY B;  4BCQ D;  1F5Q B;  2V22 B;  3TNI B;  3BLH B;  3EOC B;  1H26 B;  3TNW B;  3POM A;  4KRC B;  4EON B;  2C5X B;  4F7S B;  1D3U B;  5IF1 B;  5IDP B;  1H1R B;  1O9K A;  2WEV B;  4OR5 B;  4BCI B;  5HBJ B;  4F6S B;  1GUX B;  4YOS A;  5BNJ B;  3LQ5 B;  4NST B;  5FGK B;  3TNH B;  4UN0 A;  4F70 B;  3BLQ B;  3RGF B;  2C5N B;  4F6W B;  1H25 B;  3BHU B;  1AD6 A;  3H4C A;  4BCN D;  3F5X B;  2WIP B;  2IW8 B;  4G6L B;  5HBH B;  4CFN B;  4CRL B;  1TFB A;  1UNG D;  3TN8 B;  2IVX A;  2UZD B;  1VIN A;  4BCM B;  1GY3 B;  4YC3 B;  2C4G B;  4CFM B;  2JGZ B;  4F7J B;  2F2C A;  2UZL B;  3MY5 B;  2UZB B;  1OKV B;  2W9Z A;  3BHV B;  2W2H A;  5LQF B;  4BCH B;  1VOL A;  1P5E B;  4II5 B; 
#chains in the Genus database with same CATH topology
 5HVY B;  3KHI A;  2DXB B;  4OB1 B;  1G3N C;  3QYH B;  4EOJ B;  1E7P A;  1JSU B;  3M03 A;  3QZ5 B;  4CFW B;  5CEI B;  3O0G D;  1H1P B;  2EUF A;  4HNV A;  4ZGD B;  1FIN B;  4FX3 B;  4EOS B;  3DDP B;  1OL2 B;  2KR6 A;  3BHT B;  2DD4 B;  2WHB B;  4HLQ A;  1BU2 A;  4BCN B;  5IDN B;  2PJQ A;  3DTO A;  4EOK B;  1AHJ B;  2ZZD B;  4NC6 A;  1KXU A;  1XO2 A;  3MIA B;  4EOR B;  4EOI B;  1O9K B;  4ROE A;  5CYI B;  4TTH A;  5LMK B;  2QDY B;  4BCK B;  3PO3 S;  1H1S B;  1H27 B;  2UZE B;  4ELJ A;  2QDJ A;  2CZ0 B;  2WMB B;  3X25 B;  2D0Q B;  4I3Z B;  5DQV A;  1OIY B;  4BCQ D;  4AKI A;  3TNW B;  3VKG A;  4KRC B;  4EON B;  2QF7 A;  1H1R B;  4BCI B;  3WVE B;  4NST B;  2ZPB B;  1UGQ B;  4HNT A;  4UN0 A;  4CRL B;  2WIP B;  3DJB A;  2QQ8 A;  2UZD B;  4ZGE B;  4YC3 B;  4JX5 A;  2F2C A;  3MY5 B;  2CZ7 B;  3VYH B;  2BS3 A;  4OB3 B;  2IN3 A;  4F7S B;  4II5 B;  4Y72 B;  4OB2 B;  4BBS M;  3QYG B;  2WFY B;  4CXA B;  3TW6 A;  1OL1 B;  4CFV B;  1E9H B;  4JX4 A;  4BCJ B;  1H4L D;  2R7G A;  4EOL B;  3A8O B;  4EOO B;  3HBL A;  1H24 B;  3DL1 A;  2WJ9 A;  4YOO A;  2BPM B;  1QMZ B;  4OGR B;  2QFZ A;  2C5O B;  1UNL D;  1UGR B;  1H28 B;  1H1Q B;  3BG3 A;  4YOZ A;  2PK9 B;  2DME A;  2ZPH B;  3TW7 A;  4MFE A;  4JX6 A;  4BBR M;  2CCI B;  3DOG B;  3QHW B;  5EFQ B;  2BKZ B;  2IW6 B;  4EOM B;  2CJM B;  1GH6 B;  2DXC B;  3MY1 B;  3X20 B;  2V22 B;  3TNI B;  3BLH B;  3EOC B;  1H26 B;  1V29 B;  5IF1 B;  4M6V A;  4YOS A;  4BY1 X;  1UGS B;  5FGK B;  3TNH B;  4F70 B;  3BHU B;  4BCN D;  2IW8 B;  1UNG D;  3A8M B;  1VIN A;  4BCM B;  1GY3 B;  1OKV B;  4BCH B;  4ELL A;  2B9R A;  2WMA B;  1N4M A;  2UUE B;  5L2W B;  1GUX A;  2C5V B;  5HNB B;  4BCG B;  4MFD A;  3DDQ B;  2W9F A;  5HBE B;  2G77 A;  5HQ0 B;  4F7L B;  2PHG A;  2DD5 B;  1OIU B;  3X26 B;  3BLR B;  4HL4 A;  2WPA B;  3A8H B;  1JST B;  2G9X B;  4ZGJ B;  4BCO B;  1OGU B;  1W98 B;  3MI9 B;  3B57 A;  2WIH B;  4EOP B;  2I53 A;  4HNU A;  3A8L B;  4EOQ B;  3QWL A;  2ZPE B;  3BG5 A;  2LW4 A;  4CFU B;  3GTM S;  4CFX B;  2PK2 A;  3EJ1 B;  1FVV B;  3HB9 A;  3A8G B;  4LOC A;  4BCP B;  1JKW A;  4OB0 B;  2AHJ B;  2W96 A;  4CFU D;  2ZCF B;  2CCH B;  4IMY B;  2ZPI B;  4AKG A;  2CYZ B;  1D3U B;  1O9K A;  5BNJ B;  2ZPG B;  5IHY A;  2CZ6 B;  4AI6 A;  3BLQ B;  3RGF B;  2C5N B;  4AKH A;  1AD6 A;  3H4C A;  5HBH B;  4CFN B;  1TFB A;  5EJC A;  2IVX A;  2KMG A;  2UZB B;  2W2H A;  2WXV B;  5I5Z B;  1QLB A;  3QXE B;  4ROD A;  3QHR B;  5ICP B;  3HO8 A;  4BXX X;  2IW9 B;  4ROC A;  3X28 B;  1URC B;  2I40 B;  1OI9 B;  1VYW B;  4FM4 B;  4Z6Y A;  1PKD B;  4F7N B;  4F6U B;  1FKM A;  4MIM A;  2W99 A;  1UNH D;  4BCQ B;  3WVD B;  3EID B;  3QYB A;  1IRE B;  3HZJ A;  3K7A M;  2X1N B;  2BS4 A;  4EC9 B;  2PMI B;  4BCM D;  3G33 B;  1ZP2 A;  2BS2 A;  2DPP B;  1OKW B;  2C6T B;  4BY7 X;  3VYG B;  2ZPF B;  4KRD B;  5ACB A;  1JOW A;  5DQW A;  4BCF B;  3HHT B;  1ENW A;  2CZ1 B;  3QYE A;  1TD6 A;  2QGS A;  3VKH A;  1C9B A;  4EC8 B;  1AIS B;  1F5Q B;  3POM A;  3QZ9 B;  2C5X B;  1UGP B;  4QSH A;  5IDP B;  2WEV B;  4OR5 B;  5HBJ B;  4F6S B;  1GUX B;  3LQ5 B;  4F6W B;  3NDQ A;  1H25 B;  3BG9 A;  3F5X B;  4G6L B;  3TN8 B;  4CFM B;  2C4G B;  2JGZ B;  4F7J B;  2UZL B;  2W9Z A;  3BHV B;  3X24 B;  5LQF B;  1VOL A;  1P5E B; 
#chains in the Genus database with same CATH homology
 2WXV B;  4Y72 B;  4ELL A;  5I5Z B;  2B9R A;  5HVY B;  2WMA B;  1N4M A;  2WFY B;  1G3N C;  2UUE B;  4CXA B;  5L2W B;  4EOJ B;  1GUX A;  2C5V B;  5HNB B;  1JSU B;  1OL1 B;  3M03 A;  4BCG B;  4CFV B;  4ROD A;  3QHR B;  4CFW B;  5ICP B;  3DDQ B;  2W9F A;  5CEI B;  5HBE B;  1E9H B;  5HQ0 B;  2IW9 B;  4F7L B;  3O0G D;  1H1P B;  2PHG A;  4BCJ B;  4ROC A;  1H4L D;  1URC B;  2EUF A;  2R7G A;  2I40 B;  1OI9 B;  1OIU B;  4EOL B;  1VYW B;  1PKD B;  3BLR B;  1FIN B;  2WPA B;  4EOO B;  4F7N B;  1JST B;  4FX3 B;  4F6U B;  2G9X B;  4EOS B;  2W99 A;  1UNH D;  1H24 B;  4BCQ B;  4BCO B;  1OGU B;  3DDP B;  4YOO A;  1OL2 B;  3EID B;  2BPM B;  1W98 B;  1QMZ B;  3MI9 B;  4OGR B;  3K7A M;  2WIH B;  2X1N B;  3BHT B;  4EOP B;  2WHB B;  2C5O B;  4EC9 B;  2PMI B;  2I53 A;  1UNL D;  1BU2 A;  4BCM D;  4EOQ B;  3G33 B;  4BCN B;  5IDN B;  1H28 B;  1H1Q B;  1ZP2 A;  4EOK B;  4YOZ A;  2PK9 B;  1KXU A;  1XO2 A;  3MIA B;  4EOR B;  1OKW B;  4EOI B;  4CFU B;  2C6T B;  1O9K B;  4ROE A;  4KRD B;  5ACB A;  5CYI B;  4TTH A;  2CCI B;  4CFX B;  5LMK B;  1JOW A;  4BCK B;  4BCF B;  3DOG B;  3QHW B;  5EFQ B;  2PK2 A;  2BKZ B;  1H1S B;  1H27 B;  2UZE B;  2IW6 B;  3EJ1 B;  1FVV B;  4ELJ A;  2QDJ A;  4EOM B;  2CJM B;  1GH6 B;  2WMB B;  4I3Z B;  1C9B A;  4BCP B;  1JKW A;  1OIY B;  3MY1 B;  4CFU D;  2W96 A;  4EC8 B;  1AIS B;  2CCH B;  4IMY B;  4BCQ D;  1F5Q B;  2V22 B;  3TNI B;  3BLH B;  3EOC B;  1H26 B;  3TNW B;  3POM A;  4KRC B;  4EON B;  2C5X B;  4F7S B;  1D3U B;  5IF1 B;  5IDP B;  1H1R B;  1O9K A;  2WEV B;  4OR5 B;  4BCI B;  5HBJ B;  4F6S B;  1GUX B;  4YOS A;  5BNJ B;  3LQ5 B;  4NST B;  5FGK B;  3TNH B;  4UN0 A;  4F70 B;  3BLQ B;  3RGF B;  2C5N B;  4F6W B;  1H25 B;  3BHU B;  1AD6 A;  3H4C A;  4BCN D;  3F5X B;  2WIP B;  2IW8 B;  4G6L B;  5HBH B;  4CFN B;  4CRL B;  1TFB A;  1UNG D;  3TN8 B;  2IVX A;  2UZD B;  1VIN A;  4BCM B;  1GY3 B;  4YC3 B;  2C4G B;  4CFM B;  2JGZ B;  4F7J B;  2F2C A;  2UZL B;  3MY5 B;  2UZB B;  1OKV B;  2W9Z A;  3BHV B;  2W2H A;  5LQF B;  4BCH B;  1VOL A;  1P5E B;  4II5 B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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