2C5ZA

Structure and ctd binding of the set2 sri domain
Total Genus 35
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
35
sequence length
93
structure length
93
Chain Sequence
VSQSQRLEHNWNKFFASFVPNLIKKNPQSKQFDHENIKQCAKDIVKILTTKELKKDSSRAPPDDLTKGKRHKVKEFINSYMDKIILKKKQKKA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structure and carboxyl-terminal domain (CTD) binding of the Set2 SRI domain that couples histone H3 Lys36 methylation to transcription.
pubmed doi rcsb
molecule tags Transcription
source organism Saccharomyces cerevisiae
molecule keywords SET DOMAIN PROTEIN 2
total genus 35
structure length 93
sequence length 93
ec nomenclature ec 2.1.1.43: Histone-lysine N-methyltransferase.
pdb deposition date 2005-11-03

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF08236 SRI SRI (Set2 Rpb1 interacting) domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1740.100 Mainly Alpha Orthogonal Bundle Rna Polymerase Sigma Factor; Chain: A Rna Polymerase Sigma Factor; Chain: A 2c5zA00
2A7OA 2C5ZA
chains in the Genus database with same CATH superfamily
3FUNA 3FU3A 3RASA 3CZGA 4R5VA 1Q0LA 4X2UA 4PVBA 2C5ZA 3FULA 3CHPA 4OOFA 1MW2A 4ZX4A 5JMPA 4QHPA 3FHEA 3AUAA 4AR8A 5JNLA 4Q4EA 3FUJA 3B34A 4JNDA 4MS6A 4ZN6A 3VVMA 4R5TA 3FUEA 4Y6SA 3B7TA 5DLLA 4ZX3A 3CHQA 2JD1A 1Q0QA 4R7LA 4XO4A 5EV7A 5JO0A 4FLRA 1H19A 3FH5A 3U9WA 4Q4IA 3B2XA 4Y6PA 4ZQFA 3HW2A 3RC3A 3UERA 3FU0A 4XN5A 3FTUA 3B7SA 4FLQA 2WZGA 2HPTA 2RJIA 4PW4A 1SG7A 4FLSA 4GAEA 4BKXA 2FFLA 2PL5A 1X3WA 3KEDA 3B3BA 2VJ8A 4XMVA 1K5HA 2DQMA 1T1RA 3JSZA 3FTVA 3A14A 4XMUA 3T8VA 2R59A 3FTXA 2JCYA 3FTZA 4K5MA 2JCVA 2A7OA 3Q43A 4PU2A 2C82A 3FUFA 1H3LA 3FTYA 4XNAA 4OOEA 1T1SA 4XN4A 3CHSA 3CZLA 3FUKA 4XN8A 2PUSA 4XN1A 3FH8A 5FWQA 4XN7A 3WQRA 4A03A 2DQ6A 2ZXGA 4ZQTA 5DYFA 4K5OA 3ANLA 4QPEA 4ZW6A 4ZQEA 1ZS2A 1JGIA 2QJ1A 3ZHYA 2JD0A 3WQSB 2HPOA 2MAPA 4ZW5A 3ANNA 3AU8A 2R72A 3CHOA 5JAZA 2WPGA 3ZHXA 2Y1GA 3FH7A 4ZQGA 3PUUA 2JCXA 5HLTA 4DPRA 1ONNA 3ANMA 3QJXA 3FTSA 4NQWA 5AENA 1ONPA 4XN9A 3AU9A 2Y1FA 5JMWA 1ONOA 1MW1A 3ZHZA 4RSYA 3FUMA 2XPZA 4L2LA 3FUDA 4AICA 1MVYA 5HNFA 3CXBA 4MKTA 3WQQA 1GW6A 3B7RL 4XMZA 3UCQA 4K5NA 4ZX6A 4KP7A 2XQ0A 2JV7A 5JBIA 4XMWA 1S46A 2R70A 3CIAA 3ZI0A 4GAAA 1MW0A 4ZW8A 3EBGA 2B61A 2Y1CA 3EBIA 4XO3A 4AR9A 4QIRA 3T0YA 3JT1A 4XNDA 3FTWA 3FU6A 4Y67A 3CHRA 2WZFA 3EBHA 4XMTA 2O7GA 4ARFA 1G5AA 1HS6A 3B37A 4FCAA 4FLOA 3IIEA 4K5LA 1Q0HA 3Q44A 4R5XA 1MW3A 2VLAA 4RCVA 5JC1A 1SQMA 2PGGA 1R0LA 1RP3A 3B7UX 4AR1A 3R0IA 4XN2A 4ZW3A 3A06A 1JVSA 2JD2A 4QMEA 4XNBA 4K5PA 4J3BA 4RVBA 3FUIA 5DULA 4Y6RA 4ZW7A 2Y1DA 5HNHA 4XMXA 1SC5A 4LUPA 1OR7A 3FU5A 4CXFA 3B2PA 2GTQA 4QUOA 4XO5A 2XPYA 2Y1EA 3UEQA 2MAOA 3CZKA 4ZX5A 5BPPA 3CZEA 1R0KA 4ZQHA 3FUHA 3VVLA 2QVWA 3RC8A 4AYSA 2EGHA 1JG9A 1X3ZA
chains in the Genus database with same CATH topology
3FUNA 3FU3A 3RASA 3CZGA 4R5VA 1Q0LA 4X2UA 4PVBA 2C5ZA 3FULA 3CHPA 4OOFA 1MW2A 4ZX4A 5JMPA 4QHPA 3FHEA 3AUAA 4AR8A 5JNLA 4Q4EA 3FUJA 3B34A 4JNDA 4MS6A 4ZN6A 3VVMA 4R5TA 3FUEA 4Y6SA 3B7TA 5DLLA 4ZX3A 3CHQA 2JD1A 1Q0QA 4R7LA 4XO4A 5EV7A 5JO0A 4FLRA 1H19A 3FH5A 3U9WA 4Q4IA 3B2XA 4Y6PA 4ZQFA 3RC3A 3UERA 3FU0A 4XN5A 3FTUA 3B7SA 4FLQA 2WZGA 2HPTA 2RJIA 4PW4A 1SG7A 4FLSA 4GAEA 4BKXA 2FFLA 2PL5A 1X3WA 3KEDA 3B3BA 2VJ8A 4XMVA 1K5HA 2DQMA 1T1RA 3JSZA 3FTVA 3A14A 4XMUA 3T8VA 2R59A 3FTXA 2JCYA 3FTZA 4K5MA 2JCVA 2A7OA 3Q43A 4PU2A 2C82A 3FUFA 1H3LA 3FTYA 4XNAA 4OOEA 1T1SA 4XN4A 3CHSA 3CZLA 3FUKA 4XN8A 2PUSA 4XN1A 3FH8A 5FWQA 4XN7A 3WQRA 4A03A 2DQ6A 2ZXGA 4ZQTA 5DYFA 4K5OA 3ANLA 4QPEA 4ZW6A 4ZQEA 1ZS2A 1JGIA 2QJ1A 3ZHYA 2JD0A 3WQSB 2HPOA 2MAPA 4ZW5A 3ANNA 3AU8A 2R72A 3CHOA 5JAZA 2WPGA 3ZHXA 2Y1GA 3FH7A 4ZQGA 3PUUA 2JCXA 5HLTA 4DPRA 1ONNA 3ANMA 3QJXA 3FTSA 4NQWA 5AENA 1ONPA 4XN9A 3AU9A 2Y1FA 5JMWA 1ONOA 1MW1A 3ZHZA 4RSYA 3FUMA 2XPZA 4L2LA 3FUDA 4AICA 1MVYA 5HNFA 4MKTA 3WQQA 1GW6A 3B7RL 4XMZA 3UCQA 4K5NA 4ZX6A 4KP7A 2XQ0A 2JV7A 5JBIA 4XMWA 1S46A 2R70A 3CIAA 3ZI0A 4GAAA 1MW0A 4ZW8A 3EBGA 2B61A 2Y1CA 3EBIA 4XO3A 4AR9A 4QIRA 3T0YA 3JT1A 4XNDA 3FTWA 3FU6A 4Y67A 3CHRA 2WZFA 3EBHA 4XMTA 2O7GA 4ARFA 1G5AA 1HS6A 3B37A 4FCAA 4FLOA 3IIEA 4K5LA 1Q0HA 3Q44A 4R5XA 1MW3A 2VLAA 4RCVA 5JC1A 1SQMA 2PGGA 1R0LA 1RP3A 3B7UX 4AR1A 3R0IA 4XN2A 4ZW3A 3A06A 1JVSA 2JD2A 4QMEA 4XNBA 4K5PA 4J3BA 4RVBA 3FUIA 5DULA 4Y6RA 4ZW7A 2Y1DA 5HNHA 4XMXA 1SC5A 4LUPA 1OR7A 3FU5A 4CXFA 3B2PA 2GTQA 4QUOA 4XO5A 2XPYA 2Y1EA 3UEQA 2MAOA 3CZKA 4ZX5A 5BPPA 3CZEA 1R0KA 4ZQHA 3FUHA 3VVLA 2QVWA 3RC8A 4AYSA 2EGHA 1JG9A 1X3ZA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2A7O A;  2C5Z A; 
#chains in the Genus database with same CATH topology
 3FUN A;  3FU3 A;  3RAS A;  3CZG A;  4R5V A;  1Q0L A;  4X2U A;  4PVB A;  2C5Z A;  3FUL A;  3CHP A;  4OOF A;  1MW2 A;  4ZX4 A;  5JMP A;  4QHP A;  3FHE A;  3AUA A;  4AR8 A;  5JNL A;  4Q4E A;  3FUJ A;  3B34 A;  4JND A;  4MS6 A;  4ZN6 A;  3VVM A;  4R5T A;  3FUE A;  4Y6S A;  3B7T A;  5DLL A;  4ZX3 A;  3CHQ A;  2JD1 A;  1Q0Q A;  4R7L A;  4XO4 A;  5EV7 A;  5JO0 A;  4FLR A;  1H19 A;  3FH5 A;  3U9W A;  4Q4I A;  3B2X A;  4Y6P A;  4ZQF A;  3HW2 A;  3RC3 A;  3UER A;  3FU0 A;  4XN5 A;  3FTU A;  3B7S A;  4FLQ A;  2WZG A;  2HPT A;  2RJI A;  4PW4 A;  1SG7 A;  4FLS A;  4GAE A;  4BKX A;  2FFL A;  2PL5 A;  1X3W A;  3KED A;  3B3B A;  2VJ8 A;  4XMV A;  1K5H A;  2DQM A;  1T1R A;  3JSZ A;  3FTV A;  3A14 A;  4XMU A;  3T8V A;  2R59 A;  3FTX A;  2JCY A;  3FTZ A;  4K5M A;  2JCV A;  2A7O A;  3Q43 A;  4PU2 A;  2C82 A;  3FUF A;  1H3L A;  3FTY A;  4XNA A;  4OOE A;  1T1S A;  4XN4 A;  3CHS A;  3CZL A;  3FUK A;  4XN8 A;  2PUS A;  4XN1 A;  3FH8 A;  5FWQ A;  4XN7 A;  3WQR A;  4A03 A;  2DQ6 A;  2ZXG A;  4ZQT A;  5DYF A;  4K5O A;  3ANL A;  4QPE A;  4ZW6 A;  4ZQE A;  1ZS2 A;  1JGI A;  2QJ1 A;  3ZHY A;  2JD0 A;  3WQS B;  2HPO A;  2MAP A;  4ZW5 A;  3ANN A;  3AU8 A;  2R72 A;  3CHO A;  5JAZ A;  2WPG A;  3ZHX A;  2Y1G A;  3FH7 A;  4ZQG A;  3PUU A;  2JCX A;  5HLT A;  4DPR A;  1ONN A;  3ANM A;  3QJX A;  3FTS A;  4NQW A;  5AEN A;  1ONP A;  4XN9 A;  3AU9 A;  2Y1F A;  5JMW A;  1ONO A;  1MW1 A;  3ZHZ A;  4RSY A;  3FUM A;  2XPZ A;  4L2L A;  3FUD A;  4AIC A;  1MVY A;  5HNF A;  3CXB A;  4MKT A;  3WQQ A;  1GW6 A;  3B7R L;  4XMZ A;  3UCQ A;  4K5N A;  4ZX6 A;  4KP7 A;  2XQ0 A;  2JV7 A;  5JBI A;  4XMW A;  1S46 A;  2R70 A;  3CIA A;  3ZI0 A;  4GAA A;  1MW0 A;  4ZW8 A;  3EBG A;  2B61 A;  2Y1C A;  3EBI A;  4XO3 A;  4AR9 A;  4QIR A;  3T0Y A;  3JT1 A;  4XND A;  3FTW A;  3FU6 A;  4Y67 A;  3CHR A;  2WZF A;  3EBH A;  4XMT A;  2O7G A;  4ARF A;  1G5A A;  1HS6 A;  3B37 A;  4FCA A;  4FLO A;  3IIE A;  4K5L A;  1Q0H A;  3Q44 A;  4R5X A;  1MW3 A;  2VLA A;  4RCV A;  5JC1 A;  1SQM A;  2PGG A;  1R0L A;  1RP3 A;  3B7U X;  4AR1 A;  3R0I A;  4XN2 A;  4ZW3 A;  3A06 A;  1JVS A;  2JD2 A;  4QME A;  4XNB A;  4K5P A;  4J3B A;  4RVB A;  3FUI A;  5DUL A;  4Y6R A;  4ZW7 A;  2Y1D A;  5HNH A;  4XMX A;  1SC5 A;  4LUP A;  1OR7 A;  3FU5 A;  4CXF A;  3B2P A;  2GTQ A;  4QUO A;  4XO5 A;  2XPY A;  2Y1E A;  3UEQ A;  2MAO A;  3CZK A;  4ZX5 A;  5BPP A;  3CZE A;  1R0K A;  4ZQH A;  3FUH A;  3VVL A;  2QVW A;  3RC8 A;  4AYS A;  2EGH A;  1JG9 A;  1X3Z A; 
#chains in the Genus database with same CATH homology
 3FUN A;  3FU3 A;  3RAS A;  3CZG A;  4R5V A;  1Q0L A;  4X2U A;  4PVB A;  2C5Z A;  3FUL A;  3CHP A;  4OOF A;  1MW2 A;  4ZX4 A;  5JMP A;  4QHP A;  3FHE A;  3AUA A;  4AR8 A;  5JNL A;  4Q4E A;  3FUJ A;  3B34 A;  4JND A;  4MS6 A;  4ZN6 A;  3VVM A;  4R5T A;  3FUE A;  4Y6S A;  3B7T A;  5DLL A;  4ZX3 A;  3CHQ A;  2JD1 A;  1Q0Q A;  4R7L A;  4XO4 A;  5EV7 A;  5JO0 A;  4FLR A;  1H19 A;  3FH5 A;  3U9W A;  4Q4I A;  3B2X A;  4Y6P A;  4ZQF A;  3RC3 A;  3UER A;  3FU0 A;  4XN5 A;  3FTU A;  3B7S A;  4FLQ A;  2WZG A;  2HPT A;  2RJI A;  4PW4 A;  1SG7 A;  4FLS A;  4GAE A;  4BKX A;  2FFL A;  2PL5 A;  1X3W A;  3KED A;  3B3B A;  2VJ8 A;  4XMV A;  1K5H A;  2DQM A;  1T1R A;  3JSZ A;  3FTV A;  3A14 A;  4XMU A;  3T8V A;  2R59 A;  3FTX A;  2JCY A;  3FTZ A;  4K5M A;  2JCV A;  2A7O A;  3Q43 A;  4PU2 A;  2C82 A;  3FUF A;  1H3L A;  3FTY A;  4XNA A;  4OOE A;  1T1S A;  4XN4 A;  3CHS A;  3CZL A;  3FUK A;  4XN8 A;  2PUS A;  4XN1 A;  3FH8 A;  5FWQ A;  4XN7 A;  3WQR A;  4A03 A;  2DQ6 A;  2ZXG A;  4ZQT A;  5DYF A;  4K5O A;  3ANL A;  4QPE A;  4ZW6 A;  4ZQE A;  1ZS2 A;  1JGI A;  2QJ1 A;  3ZHY A;  2JD0 A;  3WQS B;  2HPO A;  2MAP A;  4ZW5 A;  3ANN A;  3AU8 A;  2R72 A;  3CHO A;  5JAZ A;  2WPG A;  3ZHX A;  2Y1G A;  3FH7 A;  4ZQG A;  3PUU A;  2JCX A;  5HLT A;  4DPR A;  1ONN A;  3ANM A;  3QJX A;  3FTS A;  4NQW A;  5AEN A;  1ONP A;  4XN9 A;  3AU9 A;  2Y1F A;  5JMW A;  1ONO A;  1MW1 A;  3ZHZ A;  4RSY A;  3FUM A;  2XPZ A;  4L2L A;  3FUD A;  4AIC A;  1MVY A;  5HNF A;  4MKT A;  3WQQ A;  1GW6 A;  3B7R L;  4XMZ A;  3UCQ A;  4K5N A;  4ZX6 A;  4KP7 A;  2XQ0 A;  2JV7 A;  5JBI A;  4XMW A;  1S46 A;  2R70 A;  3CIA A;  3ZI0 A;  4GAA A;  1MW0 A;  4ZW8 A;  3EBG A;  2B61 A;  2Y1C A;  3EBI A;  4XO3 A;  4AR9 A;  4QIR A;  3T0Y A;  3JT1 A;  4XND A;  3FTW A;  3FU6 A;  4Y67 A;  3CHR A;  2WZF A;  3EBH A;  4XMT A;  2O7G A;  4ARF A;  1G5A A;  1HS6 A;  3B37 A;  4FCA A;  4FLO A;  3IIE A;  4K5L A;  1Q0H A;  3Q44 A;  4R5X A;  1MW3 A;  2VLA A;  4RCV A;  5JC1 A;  1SQM A;  2PGG A;  1R0L A;  1RP3 A;  3B7U X;  4AR1 A;  3R0I A;  4XN2 A;  4ZW3 A;  3A06 A;  1JVS A;  2JD2 A;  4QME A;  4XNB A;  4K5P A;  4J3B A;  4RVB A;  3FUI A;  5DUL A;  4Y6R A;  4ZW7 A;  2Y1D A;  5HNH A;  4XMX A;  1SC5 A;  4LUP A;  1OR7 A;  3FU5 A;  4CXF A;  3B2P A;  2GTQ A;  4QUO A;  4XO5 A;  2XPY A;  2Y1E A;  3UEQ A;  2MAO A;  3CZK A;  4ZX5 A;  5BPP A;  3CZE A;  1R0K A;  4ZQH A;  3FUH A;  3VVL A;  2QVW A;  3RC8 A;  4AYS A;  2EGH A;  1JG9 A;  1X3Z A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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