2C6BA

Solution structure of the c4 zinc-finger domain of hdm2
Total Genus 1
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
1
sequence length
46
structure length
46
Chain Sequence
SFEEDPEISLADYWKCTSCNEMNPPLPSHCNRCWALRENWLPEDKG
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Solution Structure of the C4 Zinc Finger Domain of Hdm2.
pubmed doi rcsb
molecule keywords UBIQUITIN-PROTEIN LIGASE E3 MDM2
molecule tags Ligase
source organism Homo sapiens
total genus 1
structure length 46
sequence length 46
ec nomenclature ec 2.3.2.27: RING-type E3 ubiquitin transferase.
pdb deposition date 2005-11-08

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00641 zf-RanBP Zn-finger in Ran binding protein and others
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.20.28.140 Mainly Beta Single Sheet Rubrerythrin, domain 2 Rubrerythrin, domain 2 2c6bA00
3B08B 2C6BA 2C6AA 2J9UB 4XXBB 3P2AA 2PPTA 3B0AB
chains in the Genus database with same CATH superfamily
2WAQP 1Y1VL 1BFYA 1PZXA 1TWCL 3GTQL 5M5XL 3RZDL 1IRNA 3PZAA 2APOB 2NYDA 4A3CL 4C3IL 1PFUA 2AUSB 3MQKB 3GTLL 1Y1WL 4A3GL 4AHXA 3HOZL 4BBSL 3PKIA 1NXEA 4POGA 4C3JL 2JA5L 5IYDL 5GAGc 3S17L 1VZHA 3H99A 3S2HL 1F4LA 1TWAL 1FHHA 2KKDA 3S2DL 2RDVA 1RB9A 3FDJA 4YWLA 2EY4E 3B0AB 2R7ZL 1CAAA 4AR4A 2J9UB 4YWMA 3P2AA 2XJRA 5AI2A 1TWGL 1NNQA 2V0FA 1LKMA 3S1ML 2CKAA 2ERSA 5M5YL 2C6AA 2HR5A 2H12A 5IY0A 3LWOB 3PO3L 4A3FL 1I50L 2ERJA 4A3IL 1LKPA 1QQTA 2XJTA 3RZTA 2E2HL 2ZIXA 3B08B 4Y7NL 4AHYA 1OWBA 1ODHA 5C3EL 1I6HL 3GTJL 2A6HD 4B8CD 4ME3A 3LWVB 3RYGA 3CQZL 3MSUA 5FJ8L 3PO2L 2RFKB 5M5WL 2JA7L 5IYBL 3IU3I 5IP9L 2A6ED 5M3FL 3KYWA 1BQ9A 3HAXC 3I4ML 1S2ZA 3PKJA 4A3KL 3P8BA 5DM71 2YU9L 3JR7A 6RXNA 2BE5D 1R0IA 2CKCA 1WJVA 3S1NL 1R0JA 3GTGL 4K9FA 5MFZA 1PFWA 3KYYA 1ZRPA 3QVDA 2M6PA 4U671 3H9BA 3S14L 4GS7D 1T9QA 1R0FA 1B71A 3I4NL 5C44L 2MS3A 3M4OL 1PFVA 1YUXA 3MPSA 5GAEc 3GTKL 2CR8A 1R9TL 1LTLA 4ZN3B 1K83L 2JI2A 2QL0A 2JA6L 1R0GA 1BRFA 5K2ME 3LNLA 4AI1A 2O5JD 1RYQA 2GMGA 2A69D 5C4JL 1IU5A 1BQ8A 1FHMA 3FKIL 4G6BA 2Y0SP 5AN9H 3HOWL 3HJWB 2PMZP 1SFOL 1H7VA 2NVTL 4JAFA 3J7Y1 1P7PA 1S30A 5JVG1 2XJQA 3S15L 5AI3A 2K2DA 3GTML 2WB1P 2M4YA 2Z3RB 2V0EA 2L0ZA 2PVEA 1CADA 3HKZP 4C2M1 3PL5A 1YV1A 3M3YL 4AI2A 3NFPI 2E2JL 1C09A 2PSMC 3HOYL 2NVQL 2XJSA 4A3LL 2KN9A 1VZIA 5IYCL 2DSXA 4C3HL 1IW7D 1YK4A 3PIP1 2R93L 5EINC 4RXNA 3HOVL 3WWNB 3HOUL 3RZ6A 1TWFL 1BE7A 2PVXA 2VUML 1JYBA 4AHWA 7RXNA 2B5ID 3LWQB 3J7Z1 3S1RL 3H0GL 4AR6A 3K35A 3SS2A 2B63L 3RZOL 3KYUA 4V196 4AI0A 4AI3A 1B2JA 3A44A 1IU6A 2NVYL 5JVH1 1DX8A 4JAEA 5H1Sc 3HOXL 1RDGA 4A93L 2JI3A 5EIOC 5GADc 4A3ML 3LWPB 4AHZA 4E6YA 3GTOL 1SMMA 3HJYB 3LWRB 3PWFA 4A3DL 2VL6A 4ZN1B 3ZG6A 3H3VM 5DM61 5FLML 4BY7L 1VCXA 1E8JA 1NXGA 4A3EL 1QCVA 2C6BA 1Z92B 2PYAA 2LCQA 4JADA 1RDVA 1RYTA 3QQCE 3PIO1 1IROA 1SMWA 1T9OA 5MFPA 1RWDA 4LHLA 3GTPL 3WWLA 2R92L 1SMUA 4A3BL 2XJPA 2M4VA 1B13A 3S1QL 5M3ML 4QIWP 2JI1A 2HVYC 1PFYA 1DVBA 2XJVA 1LKOA 5IP7L 1VZGA 3LPEB 4BXXL 4BY1L 1T9PA 1S24A 4XGHA 5C4XL 2E2IL 4A3JL 4BBRL 4TVMA 8RXNA 3VPBE 4LHNA 2XJUA 1I3QL 5MGNA 4AYBP 1YK5A 2M6OA 3H97A 1B2OA 3H9CA 1R0HA 2AYJA 1QYBA 3KYXA 1WCML 1OWCA 2A68D 4JAGA 4XXBB 2PPTA 5GAHc 4X6AL 5MF6A 3K7AL 4AR5A 1TWHL 4POFA 4AR3A 2Z3QB 4UY81 5RXNA 3S16L 4WFN1 1YUZA 4Y52L 2V3BB 2JA8L 2NVXL 3KYVA 4TPUA 5MLC3 2AQCA
chains in the Genus database with same CATH topology
3B08B 4AHYA 5JVG1 1OWBA 2XJQA 1VCXA 1BFYA 1E8JA 1ODHA 1NXGA 5AI3A 1IRNA 2K2DA 3PZAA 1QCVA 2M4YA 2A6HD 2C6BA 2NYDA 2Z3RB 4B8CD 1Z92B 2V0EA 2L0ZA 2PYAA 4ME3A 2PVEA 1CADA 3RYGA 3MSUA 2LCQA 4JADA 1RDVA 1YV1A 1RYTA 4AI2A 3NFPI 3QQCE 3PIO1 1C09A 2PSMC 1IROA 1SMWA 3IU3I 1T9OA 5MFPA 1RWDA 2A6ED 2XJSA 4AHXA 4LHLA 3PKIA 1NXEA 3WWLA 2KN9A 1VZIA 1SMUA 4POGA 3KYWA 2DSXA 1BQ9A 1IW7D 1YK4A 2XJPA 3PIP1 2M4VA 1S2ZA 1B13A 3PKJA 3P8BA 5DM71 5EINC 4RXNA 2JI1A 3WWNB 5GAGc 3RZ6A 6RXNA 2BE5D 1DVBA 1VZHA 2XJVA 1BE7A 2PVXA 1LKOA 1R0IA 2CKCA 1WJVA 1R0JA 2KKDA 1FHHA 4K9FA 5MFZA 1JYBA 2RDVA 1RB9A 4AHWA 3KYYA 1ZRPA 2B5ID 1VZGA 3LPEB 2M6PA 3QVDA 4YWLA 7RXNA 1T9PA 3J7Z1 1S24A 3B0AB 4U671 4XGHA 1CAAA 4AR4A 2J9UB 4YWMA 3P2AA 4GS7D 2XJRA 1T9QA 5AI2A 1R0FA 1B71A 4AR6A 3K35A 4TVMA 1NNQA 2V0FA 8RXNA 2MS3A 1LKMA 3SS2A 3VPBE 4LHNA 2XJUA 1YUXA 3MPSA 5MGNA 5GAEc 2CKAA 2ERSA 1YK5A 2CR8A 2M6OA 1B2OA 3KYUA 4AI0A 4V196 2C6AA 2HR5A 2H12A 4AI3A 1R0HA 5IY0A 1LTLA 2AYJA 1QYBA 3KYXA 4ZN3B 1B2JA 3A44A 1IU6A 1OWCA 2A68D 4JAGA 4XXBB 2JI2A 2QL0A 2PPTA 5GAHc 1R0GA 5MF6A 1BRFA 5K2ME 4AR5A 4POFA 5JVH1 1DX8A 4JAEA 4AR3A 5H1Sc 1RDGA 2Z3QB 3LNLA 4AI1A 2O5JD 2ERJA 4UY81 2JI3A 1RYQA 5GADc 5EIOC 5RXNA 2GMGA 4WFN1 1YUZA 2A69D 4AHZA 4E6YA 1IU5A 1BQ8A 2V3BB 1FHMA 4G6BA 1SMMA 1LKPA 5AN9H 2XJTA 3PWFA 2VL6A 4ZN1B 3RZTA 3ZG6A 1H7VA 3KYVA 2ZIXA 4TPUA 5MLC3 4JAFA 3J7Y1 5DM61 1S30A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3B08 B;  2C6B A;  2C6A A;  2J9U B;  4XXB B;  3P2A A;  2PPT A;  3B0A B; 
#chains in the Genus database with same CATH topology
 2WAQ P;  1Y1V L;  1BFY A;  1PZX A;  1TWC L;  3GTQ L;  5M5X L;  3RZD L;  1IRN A;  3PZA A;  2APO B;  2NYD A;  4A3C L;  4C3I L;  1PFU A;  2AUS B;  3MQK B;  3GTL L;  1Y1W L;  4A3G L;  4AHX A;  3HOZ L;  4BBS L;  3PKI A;  1NXE A;  4POG A;  4C3J L;  2JA5 L;  5IYD L;  5GAG c;  3S17 L;  1VZH A;  3H99 A;  3S2H L;  1F4L A;  1TWA L;  1FHH A;  2KKD A;  3S2D L;  2RDV A;  1RB9 A;  3FDJ A;  4YWL A;  2EY4 E;  3B0A B;  2R7Z L;  1CAA A;  4AR4 A;  2J9U B;  4YWM A;  3P2A A;  2XJR A;  5AI2 A;  1TWG L;  1NNQ A;  2V0F A;  1LKM A;  3S1M L;  2CKA A;  2ERS A;  5M5Y L;  2C6A A;  2HR5 A;  2H12 A;  5IY0 A;  3LWO B;  3PO3 L;  4A3F L;  1I50 L;  2ERJ A;  4A3I L;  1LKP A;  1QQT A;  2XJT A;  3RZT A;  2E2H L;  2ZIX A;  3B08 B;  4Y7N L;  4AHY A;  1OWB A;  1ODH A;  5C3E L;  1I6H L;  3GTJ L;  2A6H D;  4B8C D;  4ME3 A;  3LWV B;  3RYG A;  3CQZ L;  3MSU A;  5FJ8 L;  3PO2 L;  2RFK B;  5M5W L;  2JA7 L;  5IYB L;  3IU3 I;  5IP9 L;  2A6E D;  5M3F L;  3KYW A;  1BQ9 A;  3HAX C;  3I4M L;  1S2Z A;  3PKJ A;  4A3K L;  3P8B A;  5DM7 1;  2YU9 L;  3JR7 A;  6RXN A;  2BE5 D;  1R0I A;  2CKC A;  1WJV A;  3S1N L;  1R0J A;  3GTG L;  4K9F A;  5MFZ A;  1PFW A;  3KYY A;  1ZRP A;  3QVD A;  2M6P A;  4U67 1;  3H9B A;  3S14 L;  4GS7 D;  1T9Q A;  1R0F A;  1B71 A;  3I4N L;  5C44 L;  2MS3 A;  3M4O L;  1PFV A;  1YUX A;  3MPS A;  5GAE c;  3GTK L;  2CR8 A;  1R9T L;  1LTL A;  4ZN3 B;  1K83 L;  2JI2 A;  2QL0 A;  2JA6 L;  1R0G A;  1BRF A;  5K2M E;  3LNL A;  4AI1 A;  2O5J D;  1RYQ A;  2GMG A;  2A69 D;  5C4J L;  1IU5 A;  1BQ8 A;  1FHM A;  3FKI L;  4G6B A;  2Y0S P;  5AN9 H;  3HOW L;  3HJW B;  2PMZ P;  1SFO L;  1H7V A;  2NVT L;  4JAF A;  3J7Y 1;  1P7P A;  1S30 A;  5JVG 1;  2XJQ A;  3S15 L;  5AI3 A;  2K2D A;  3GTM L;  2WB1 P;  2M4Y A;  2Z3R B;  2V0E A;  2L0Z A;  2PVE A;  1CAD A;  3HKZ P;  4C2M 1;  3PL5 A;  1YV1 A;  3M3Y L;  4AI2 A;  3NFP I;  2E2J L;  1C09 A;  2PSM C;  3HOY L;  2NVQ L;  2XJS A;  4A3L L;  2KN9 A;  1VZI A;  5IYC L;  2DSX A;  4C3H L;  1IW7 D;  1YK4 A;  3PIP 1;  2R93 L;  5EIN C;  4RXN A;  3HOV L;  3WWN B;  3HOU L;  3RZ6 A;  1TWF L;  1BE7 A;  2PVX A;  2VUM L;  1JYB A;  4AHW A;  7RXN A;  2B5I D;  3LWQ B;  3J7Z 1;  3S1R L;  3H0G L;  4AR6 A;  3K35 A;  3SS2 A;  2B63 L;  3RZO L;  3KYU A;  4V19 6;  4AI0 A;  4AI3 A;  1B2J A;  3A44 A;  1IU6 A;  2NVY L;  5JVH 1;  1DX8 A;  4JAE A;  5H1S c;  3HOX L;  1RDG A;  4A93 L;  2JI3 A;  5EIO C;  5GAD c;  4A3M L;  3LWP B;  4AHZ A;  4E6Y A;  3GTO L;  1SMM A;  3HJY B;  3LWR B;  3PWF A;  4A3D L;  2VL6 A;  4ZN1 B;  3ZG6 A;  3H3V M;  5DM6 1;  5FLM L;  4BY7 L;  1VCX A;  1E8J A;  1NXG A;  4A3E L;  1QCV A;  2C6B A;  1Z92 B;  2PYA A;  2LCQ A;  4JAD A;  1RDV A;  1RYT A;  3QQC E;  3PIO 1;  1IRO A;  1SMW A;  1T9O A;  5MFP A;  1RWD A;  4LHL A;  3GTP L;  3WWL A;  2R92 L;  1SMU A;  4A3B L;  2XJP A;  2M4V A;  1B13 A;  3S1Q L;  5M3M L;  4QIW P;  2JI1 A;  2HVY C;  1PFY A;  1DVB A;  2XJV A;  1LKO A;  5IP7 L;  1VZG A;  3LPE B;  4BXX L;  4BY1 L;  1T9P A;  1S24 A;  4XGH A;  5C4X L;  2E2I L;  4A3J L;  4BBR L;  4TVM A;  8RXN A;  3VPB E;  4LHN A;  2XJU A;  1I3Q L;  5MGN A;  4AYB P;  1YK5 A;  2M6O A;  3H97 A;  1B2O A;  3H9C A;  1R0H A;  2AYJ A;  1QYB A;  3KYX A;  1WCM L;  1OWC A;  2A68 D;  4JAG A;  4XXB B;  2PPT A;  5GAH c;  4X6A L;  5MF6 A;  3K7A L;  4AR5 A;  1TWH L;  4POF A;  4AR3 A;  2Z3Q B;  4UY8 1;  5RXN A;  3S16 L;  4WFN 1;  1YUZ A;  4Y52 L;  2V3B B;  2JA8 L;  2NVX L;  3KYV A;  4TPU A;  5MLC 3;  2AQC A; 
#chains in the Genus database with same CATH homology
 3B08 B;  4AHY A;  5JVG 1;  1OWB A;  2XJQ A;  1VCX A;  1BFY A;  1E8J A;  1ODH A;  1NXG A;  5AI3 A;  1IRN A;  2K2D A;  3PZA A;  1QCV A;  2M4Y A;  2A6H D;  2C6B A;  2NYD A;  2Z3R B;  4B8C D;  1Z92 B;  2V0E A;  2L0Z A;  2PYA A;  4ME3 A;  2PVE A;  1CAD A;  3RYG A;  3MSU A;  2LCQ A;  4JAD A;  1RDV A;  1YV1 A;  1RYT A;  4AI2 A;  3NFP I;  3QQC E;  3PIO 1;  1C09 A;  2PSM C;  1IRO A;  1SMW A;  3IU3 I;  1T9O A;  5MFP A;  1RWD A;  2A6E D;  2XJS A;  4AHX A;  4LHL A;  3PKI A;  1NXE A;  3WWL A;  2KN9 A;  1VZI A;  1SMU A;  4POG A;  3KYW A;  2DSX A;  1BQ9 A;  1IW7 D;  1YK4 A;  2XJP A;  3PIP 1;  2M4V A;  1S2Z A;  1B13 A;  3PKJ A;  3P8B A;  5DM7 1;  5EIN C;  4RXN A;  2JI1 A;  3WWN B;  5GAG c;  3RZ6 A;  6RXN A;  2BE5 D;  1DVB A;  1VZH A;  2XJV A;  1BE7 A;  2PVX A;  1LKO A;  1R0I A;  2CKC A;  1WJV A;  1R0J A;  2KKD A;  1FHH A;  4K9F A;  5MFZ A;  1JYB A;  2RDV A;  1RB9 A;  4AHW A;  3KYY A;  1ZRP A;  2B5I D;  1VZG A;  3LPE B;  2M6P A;  3QVD A;  4YWL A;  7RXN A;  1T9P A;  3J7Z 1;  1S24 A;  3B0A B;  4U67 1;  4XGH A;  1CAA A;  4AR4 A;  2J9U B;  4YWM A;  3P2A A;  4GS7 D;  2XJR A;  1T9Q A;  5AI2 A;  1R0F A;  1B71 A;  4AR6 A;  3K35 A;  4TVM A;  1NNQ A;  2V0F A;  8RXN A;  2MS3 A;  1LKM A;  3SS2 A;  3VPB E;  4LHN A;  2XJU A;  1YUX A;  3MPS A;  5MGN A;  5GAE c;  2CKA A;  2ERS A;  1YK5 A;  2CR8 A;  2M6O A;  1B2O A;  3KYU A;  4AI0 A;  4V19 6;  2C6A A;  2HR5 A;  2H12 A;  4AI3 A;  1R0H A;  5IY0 A;  1LTL A;  2AYJ A;  1QYB A;  3KYX A;  4ZN3 B;  1B2J A;  3A44 A;  1IU6 A;  1OWC A;  2A68 D;  4JAG A;  4XXB B;  2JI2 A;  2QL0 A;  2PPT A;  5GAH c;  1R0G A;  5MF6 A;  1BRF A;  5K2M E;  4AR5 A;  4POF A;  5JVH 1;  1DX8 A;  4JAE A;  4AR3 A;  5H1S c;  1RDG A;  2Z3Q B;  3LNL A;  4AI1 A;  2O5J D;  2ERJ A;  4UY8 1;  2JI3 A;  1RYQ A;  5GAD c;  5EIO C;  5RXN A;  2GMG A;  4WFN 1;  1YUZ A;  2A69 D;  4AHZ A;  4E6Y A;  1IU5 A;  1BQ8 A;  2V3B B;  1FHM A;  4G6B A;  1SMM A;  1LKP A;  5AN9 H;  2XJT A;  3PWF A;  2VL6 A;  4ZN1 B;  3RZT A;  3ZG6 A;  1H7V A;  3KYV A;  2ZIX A;  4TPU A;  5MLC 3;  4JAF A;  3J7Y 1;  5DM6 1;  1S30 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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