2C74A

14-3-3 protein eta (human) complexed to peptide
Total Genus 102
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
102
sequence length
235
structure length
235
Chain Sequence
GDREQLLQRARLAEQAERYDDMASAMKAVTELNEPLSNEDRNLLSVAYKNVVGARRSSWRVISSIEQKTMADGNEKKLEKVKAYREKIEKELETVCNDVLSLLDKFLIKNCNDFQYESKVFYLKMKGDYYRYLAEVASGEKKNSVVEASEAAYKEAFEISKEQMQPTHPIRLGLALNFSVFYYEIQNAPEQACLLAKQAFDDAIAELDTLNEDSYKDSTLIMQLLRDNLTLWTSD
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural basis for protein-protein interactions in the 14-3-3 protein family.
pubmed doi rcsb
molecule tags Signaling protein/peptide
source organism Homo sapiens
molecule keywords 14-3-3 PROTEIN ETA
total genus 102
structure length 235
sequence length 235
chains with identical sequence B
ec nomenclature
pdb deposition date 2005-11-17

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00244 14-3-3 14-3-3 protein
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.190.20 Mainly Alpha Up-down Bundle Delta-Endotoxin; domain 1 14-3-3 domain 2c74A00
4E2EA 2C1NA 4N7YA 5BTVA 3P1QA 4N84A 5LU1A 4FL5A 1A38A 4HKCA 4DHQA 3UALA 4DHPA 4FJ3A 5BY9A 2O8PA 4IHLA 2BTPA 4Y32A 5J31A 3IQUA 5LU2A 4DATA 1QJAA 3M50A 3P1PA 4FR3A 3T0LA 5D3FA 4DAUA 4J6SA 3UZDA 4JC3A 3RDHA 2C23A 3AXYC 1A4OA 2O98A 4DX0A 5EXAA 4DHNA 3SMOA 3IQJA 2WH0A 1YWTA 4F7RA 3SP5A 4IEAA 1O9DA 4ZDRA 3E6YA 4Y3BA 1O9CA 3UX0A 3SMKA 5EWZA 3M51A 1O9EA 2C63A 3LW1A 2C74A 4O46A 3MHRA 2O02A 4BG6A 4DNKA 3CU8A 3P1OA 2NPMA 5HF3A 3P1NA 2V7DA 3P1SA 1O9FA 3SPRA 5LHOA 4JDDA 5D2DA 3SMLA 3O8IA 3EFZA 3U9XA 4N7GA 2B05A 3IQVA 5IQPA 4Y5IA 4DHRA 4GNTA 4DHSA 1IB1A 5LX2A 1QJBA 4WRQA 3UBWA 4DHOA 4ZQ0A 3SMNA 3SMMA 5F74A 4QLIA 4DHTA 4DHUA 3T0MA 4DHMA 2BR9A 1YZ5A 2C1JA 2BQ0A 3P1RA 3NKXA 1A37A 5D3EA 5LVZA
chains in the Genus database with same CATH superfamily
4E2EA 2C1NA 4N7YA 5BTVA 2C9KA 3P1QA 3I4RA 4N84A 5LU1A 4FL5A 1A38A 4HKCA 4ARXA 4DHQA 3CQGA 3UALA 4DHPA 4FJ3A 5BY9A 4QX1A 4D8MA 2O8PA 4IHLA 1W99A 1DLCA 2BTPA 4Y32A 1JI6A 5J31A 3IQUA 3EB7A 5LU2A 4DATA 1QJAA 3M50A 3P1PA 4FR3A 3T0LA 5D3FA 4QX0A 4DAUA 4J6SA 3UZDA 4JC3A 3RDHA 2C23A 3AXYC 1A4OA 2O98A 4DX0A 1CIYA 3X0UA 5EXAA 4DHNA 4MOAA 3SMOA 3IQJA 2WH0A 1YWTA 4F7RA 3SP5A 4IEAA 1O9DA 4ZDRA 3E6YA 4Y3BA 1O9CA 3UX0A 3SMKA 1URJA 5EWZA 3M51A 1O9EA 2C63A 3LW1A 2C74A 4O46A 3MHRA 4W8JA 2O02A 4BG6A 4DNKA 3CU8A 3P1OA 2NPMA 5HF3A 3P1NA 2V7DA 3P1SA 1O9FA 3SPRA 5LHOA 4JDDA 5D2DA 3SMLA 3O8IA 3EFZA 4QX3A 3U9XA 3CQCA 4N7GA 2B05A 1S2XA 3IQVA 3ZHEB 4QX2A 5IQPA 4Y5IA 4DHRA 4GNTA 4DHSA 1IB1A 5LX2A 1QJBA 4WRQA 3UBWA 4DHOA 4ZQ0A 3SMNA 3SMMA 5F74A 4ARYA 4QLIA 4DHTA 4DHUA 3T0MA 4DHMA 2BR9A 1YZ5A 2C1JA 2BQ0A 3P1RA 1I5PA 3NKXA 1A37A 5D3EA 5LVZA
chains in the Genus database with same CATH topology
4E2EA 2C1NA 4N7YA 5BTVA 3P1QA 4N84A 5LU1A 4FL5A 1A38A 4HKCA 4DHQA 3UALA 4DHPA 4FJ3A 5BY9A 2O8PA 4IHLA 2BTPA 4Y32A 5J31A 3IQUA 5LU2A 4DATA 1QJAA 3M50A 3P1PA 4FR3A 3T0LA 5D3FA 4DAUA 4J6SA 3UZDA 4JC3A 3RDHA 2C23A 3AXYC 1A4OA 2O98A 4DX0A 5EXAA 4DHNA 3SMOA 3IQJA 2WH0A 1YWTA 4F7RA 3SP5A 4IEAA 1O9DA 4ZDRA 3E6YA 4Y3BA 1O9CA 3UX0A 3SMKA 5EWZA 3M51A 1O9EA 2C63A 3LW1A 2C74A 4O46A 3MHRA 2O02A 4BG6A 4DNKA 3CU8A 3P1OA 2NPMA 5HF3A 3P1NA 2V7DA 3P1SA 1O9FA 3SPRA 5LHOA 4JDDA 5D2DA 3SMLA 3O8IA 3EFZA 3U9XA 4N7GA 2B05A 3IQVA 5IQPA 4Y5IA 4DHRA 4GNTA 4DHSA 1IB1A 5LX2A 1QJBA 4WRQA 3UBWA 4DHOA 4ZQ0A 3SMNA 3SMMA 5F74A 4QLIA 4DHTA 4DHUA 3T0MA 4DHMA 2BR9A 1YZ5A 2C1JA 2BQ0A 3P1RA 3NKXA 1A37A 5D3EA 5LVZA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4E2E A;  2C1N A;  4N7Y A;  5BTV A;  3P1Q A;  4N84 A;  5LU1 A;  4FL5 A;  1A38 A;  4HKC A;  4DHQ A;  3UAL A;  4DHP A;  4FJ3 A;  5BY9 A;  2O8P A;  4IHL A;  2BTP A;  4Y32 A;  5J31 A;  3IQU A;  5LU2 A;  4DAT A;  1QJA A;  3M50 A;  3P1P A;  4FR3 A;  3T0L A;  5D3F A;  4DAU A;  4J6S A;  3UZD A;  4JC3 A;  3RDH A;  2C23 A;  3AXY C;  1A4O A;  2O98 A;  4DX0 A;  5EXA A;  4DHN A;  3SMO A;  3IQJ A;  2WH0 A;  1YWT A;  4F7R A;  3SP5 A;  4IEA A;  1O9D A;  4ZDR A;  3E6Y A;  4Y3B A;  1O9C A;  3UX0 A;  3SMK A;  5EWZ A;  3M51 A;  1O9E A;  2C63 A;  3LW1 A;  2C74 A;  4O46 A;  3MHR A;  2O02 A;  4BG6 A;  4DNK A;  3CU8 A;  3P1O A;  2NPM A;  5HF3 A;  3P1N A;  2V7D A;  3P1S A;  1O9F A;  3SPR A;  5LHO A;  4JDD A;  5D2D A;  3SML A;  3O8I A;  3EFZ A;  3U9X A;  4N7G A;  2B05 A;  3IQV A;  5IQP A;  4Y5I A;  4DHR A;  4GNT A;  4DHS A;  1IB1 A;  5LX2 A;  1QJB A;  4WRQ A;  3UBW A;  4DHO A;  4ZQ0 A;  3SMN A;  3SMM A;  5F74 A;  4QLI A;  4DHT A;  4DHU A;  3T0M A;  4DHM A;  2BR9 A;  1YZ5 A;  2C1J A;  2BQ0 A;  3P1R A;  3NKX A;  1A37 A;  5D3E A;  5LVZ A; 
#chains in the Genus database with same CATH topology
 4E2E A;  2C1N A;  4N7Y A;  5BTV A;  2C9K A;  3P1Q A;  3I4R A;  4N84 A;  5LU1 A;  4FL5 A;  1A38 A;  4HKC A;  4ARX A;  4DHQ A;  3CQG A;  3UAL A;  4DHP A;  4FJ3 A;  5BY9 A;  4QX1 A;  4D8M A;  2O8P A;  4IHL A;  1W99 A;  1DLC A;  2BTP A;  4Y32 A;  1JI6 A;  5J31 A;  3IQU A;  3EB7 A;  5LU2 A;  4DAT A;  1QJA A;  3M50 A;  3P1P A;  4FR3 A;  3T0L A;  5D3F A;  4QX0 A;  4DAU A;  4J6S A;  3UZD A;  4JC3 A;  3RDH A;  2C23 A;  3AXY C;  1A4O A;  2O98 A;  4DX0 A;  1CIY A;  3X0U A;  5EXA A;  4DHN A;  4MOA A;  3SMO A;  3IQJ A;  2WH0 A;  1YWT A;  4F7R A;  3SP5 A;  4IEA A;  1O9D A;  4ZDR A;  3E6Y A;  4Y3B A;  1O9C A;  3UX0 A;  3SMK A;  1URJ A;  5EWZ A;  3M51 A;  1O9E A;  2C63 A;  3LW1 A;  2C74 A;  4O46 A;  3MHR A;  4W8J A;  2O02 A;  4BG6 A;  4DNK A;  3CU8 A;  3P1O A;  2NPM A;  5HF3 A;  3P1N A;  2V7D A;  3P1S A;  1O9F A;  3SPR A;  5LHO A;  4JDD A;  5D2D A;  3SML A;  3O8I A;  3EFZ A;  4QX3 A;  3U9X A;  3CQC A;  4N7G A;  2B05 A;  1S2X A;  3IQV A;  3ZHE B;  4QX2 A;  5IQP A;  4Y5I A;  4DHR A;  4GNT A;  4DHS A;  1IB1 A;  5LX2 A;  1QJB A;  4WRQ A;  3UBW A;  4DHO A;  4ZQ0 A;  3SMN A;  3SMM A;  5F74 A;  4ARY A;  4QLI A;  4DHT A;  4DHU A;  3T0M A;  4DHM A;  2BR9 A;  1YZ5 A;  2C1J A;  2BQ0 A;  3P1R A;  1I5P A;  3NKX A;  1A37 A;  5D3E A;  5LVZ A; 
#chains in the Genus database with same CATH homology
 4E2E A;  2C1N A;  4N7Y A;  5BTV A;  3P1Q A;  4N84 A;  5LU1 A;  4FL5 A;  1A38 A;  4HKC A;  4DHQ A;  3UAL A;  4DHP A;  4FJ3 A;  5BY9 A;  2O8P A;  4IHL A;  2BTP A;  4Y32 A;  5J31 A;  3IQU A;  5LU2 A;  4DAT A;  1QJA A;  3M50 A;  3P1P A;  4FR3 A;  3T0L A;  5D3F A;  4DAU A;  4J6S A;  3UZD A;  4JC3 A;  3RDH A;  2C23 A;  3AXY C;  1A4O A;  2O98 A;  4DX0 A;  5EXA A;  4DHN A;  3SMO A;  3IQJ A;  2WH0 A;  1YWT A;  4F7R A;  3SP5 A;  4IEA A;  1O9D A;  4ZDR A;  3E6Y A;  4Y3B A;  1O9C A;  3UX0 A;  3SMK A;  5EWZ A;  3M51 A;  1O9E A;  2C63 A;  3LW1 A;  2C74 A;  4O46 A;  3MHR A;  2O02 A;  4BG6 A;  4DNK A;  3CU8 A;  3P1O A;  2NPM A;  5HF3 A;  3P1N A;  2V7D A;  3P1S A;  1O9F A;  3SPR A;  5LHO A;  4JDD A;  5D2D A;  3SML A;  3O8I A;  3EFZ A;  3U9X A;  4N7G A;  2B05 A;  3IQV A;  5IQP A;  4Y5I A;  4DHR A;  4GNT A;  4DHS A;  1IB1 A;  5LX2 A;  1QJB A;  4WRQ A;  3UBW A;  4DHO A;  4ZQ0 A;  3SMN A;  3SMM A;  5F74 A;  4QLI A;  4DHT A;  4DHU A;  3T0M A;  4DHM A;  2BR9 A;  1YZ5 A;  2C1J A;  2BQ0 A;  3P1R A;  3NKX A;  1A37 A;  5D3E A;  5LVZ A; 
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