2C8AA

Structure of the wild-type c3bot1 exoenzyme (nicotinamide-bound state, crystal form i)
Total Genus 71
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
71
sequence length
208
structure length
208
Chain Sequence
NTYQEFTNIDQAKAWGNAQYKKYGLSKSEKEAIVSYTKSASEINGKLRQNKGVINGFPSNLIKQVELLDKSFNKMKTPENIMLFRGDDPAYLGTEFQNTLLNSNGTINKTAFEKAKAKFLNKDRLEYGYISTSLMNVSQFAGRPIITKFKVAKGSKAGYIDPISAFAGQLEMLLPRHSTYHIDDMRLSSDGKQIIITATMMGTAINPK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural Basis for the Nad-Hydrolysis Mechanism and the Artt-Loop Plasticity of C3 Exoenzymes.
pubmed doi rcsb
molecule tags Transferase
source organism Clostridium botulinum
molecule keywords MONO-ADP-RIBOSYLTRANSFERASE C3
total genus 71
structure length 208
sequence length 208
chains with identical sequence B, C, D
ec nomenclature ec 2.4.2.-:
pdb deposition date 2005-12-03
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.176.10 Alpha Beta Alpha-Beta Complex Toxin ADP-ribosyltransferase; Chain A, domain 1 Toxin ADP-ribosyltransferase; Chain A, domain 1 2c8aA00
2WN6A 5GTTA 1YQYA 4GY2A 1PWVA 1GZEA 5H03A 2C8CA 1GIQA 1PWUA 5D1TA 1GXZA 4H0YA 4PKSA 2C8AA 2A78B 4XM7A 1OJZA 2C8FE 4H03A 1QS2A 1ZXVA 2WN7A 3BW8A 2C8BX 2C8DA 4PKWA 4H0VA 1R45A 4PKVA 2WN8A 1GIRA 1GY0A 4PKRA 4FXQA 5DZQA 4ELNA 3NTSA 4TR5A 4XSGB 2J3ZA 2GWMA 2J3XA 3U0JA 2C8GA 1GXYA 4XM6A 1G24A 2A9KB 2GWLA 4FMLA 1J7NA 4GF1A 5H04A 4H0TA 1GZFA 2C8HA 1R4BA 5D1SA 4XM8A 4FK7A 1OG4A 4PKQA 4XSHB 1QS1A 1UZIA 2BOVB 4H0XA 1OG3A 4PKUA 1JKYA 5D1UA 2C8EE 4WF6A 1PWPA 1PWWA 5BWMB 2WN4A 1PWQA 4DV8A 1OG1A 2C89A 1OJQA 2J3VA 2WN5A 4PKTA 3BUZA
chains in the Genus database with same CATH superfamily
2WN6A 5GTTA 1YQYA 4GY2A 1PWVA 1GZEA 5H03A 2C8CA 1GIQA 1PWUA 5D1TA 1GXZA 4H0YA 4PKSA 2C8AA 2A78B 4XM7A 1OJZA 2C8FE 4H03A 1QS2A 1ZXVA 2WN7A 3BW8A 2C8BX 2C8DA 4PKWA 4H0VA 1R45A 4PKVA 2WN8A 1GIRA 1GY0A 4PKRA 4FXQA 5DZQA 4ELNA 3NTSA 4TR5A 4XSGB 2J3ZA 2GWMA 2J3XA 3U0JA 2C8GA 1GXYA 4XM6A 1G24A 2A9KB 2GWLA 4FMLA 1J7NA 4GF1A 5H04A 4H0TA 1GZFA 2C8HA 1R4BA 5D1SA 4XM8A 4FK7A 1OG4A 4PKQA 4XSHB 1QS1A 1UZIA 2BOVB 4H0XA 1OG3A 4PKUA 1JKYA 5D1UA 2C8EE 4WF6A 1PWPA 1PWWA 5BWMB 2WN4A 1PWQA 4DV8A 1OG1A 2C89A 1OJQA 2J3VA 2WN5A 4PKTA 3BUZA
chains in the Genus database with same CATH topology
2WN6A 5GTTA 1YQYA 4GY2A 1PWVA 1GZEA 5H03A 2C8CA 1GIQA 1PWUA 5D1TA 1GXZA 4H0YA 4PKSA 2C8AA 2A78B 4XM7A 1OJZA 2C8FE 4H03A 1QS2A 1ZXVA 2WN7A 3BW8A 2C8BX 2C8DA 4PKWA 4H0VA 1R45A 4PKVA 2WN8A 1GIRA 1GY0A 4PKRA 4FXQA 5DZQA 4ELNA 3NTSA 4TR5A 4XSGB 2J3ZA 2GWMA 2J3XA 3U0JA 2C8GA 1GXYA 4XM6A 1G24A 2A9KB 2GWLA 4FMLA 1J7NA 4GF1A 5H04A 4H0TA 1GZFA 2C8HA 1R4BA 5D1SA 4XM8A 4FK7A 1OG4A 4PKQA 4XSHB 1QS1A 1UZIA 2BOVB 4H0XA 1OG3A 4PKUA 1JKYA 5D1UA 2C8EE 4WF6A 1PWPA 1PWWA 5BWMB 2WN4A 1PWQA 4DV8A 1OG1A 2C89A 1OJQA 2J3VA 2WN5A 4PKTA 3BUZA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2WN6 A;  5GTT A;  1YQY A;  4GY2 A;  1PWV A;  1GZE A;  5H03 A;  2C8C A;  1GIQ A;  1PWU A;  5D1T A;  1GXZ A;  4H0Y A;  4PKS A;  2C8A A;  2A78 B;  4XM7 A;  1OJZ A;  2C8F E;  4H03 A;  1QS2 A;  1ZXV A;  2WN7 A;  3BW8 A;  2C8B X;  2C8D A;  4PKW A;  4H0V A;  1R45 A;  4PKV A;  2WN8 A;  1GIR A;  1GY0 A;  4PKR A;  4FXQ A;  5DZQ A;  4ELN A;  3NTS A;  4TR5 A;  4XSG B;  2J3Z A;  2GWM A;  2J3X A;  3U0J A;  2C8G A;  1GXY A;  4XM6 A;  1G24 A;  2A9K B;  2GWL A;  4FML A;  1J7N A;  4GF1 A;  5H04 A;  4H0T A;  1GZF A;  2C8H A;  1R4B A;  5D1S A;  4XM8 A;  4FK7 A;  1OG4 A;  4PKQ A;  4XSH B;  1QS1 A;  1UZI A;  2BOV B;  4H0X A;  1OG3 A;  4PKU A;  1JKY A;  5D1U A;  2C8E E;  4WF6 A;  1PWP A;  1PWW A;  5BWM B;  2WN4 A;  1PWQ A;  4DV8 A;  1OG1 A;  2C89 A;  1OJQ A;  2J3V A;  2WN5 A;  4PKT A;  3BUZ A; 
#chains in the Genus database with same CATH topology
 2WN6 A;  5GTT A;  1YQY A;  4GY2 A;  1PWV A;  1GZE A;  5H03 A;  2C8C A;  1GIQ A;  1PWU A;  5D1T A;  1GXZ A;  4H0Y A;  4PKS A;  2C8A A;  2A78 B;  4XM7 A;  1OJZ A;  2C8F E;  4H03 A;  1QS2 A;  1ZXV A;  2WN7 A;  3BW8 A;  2C8B X;  2C8D A;  4PKW A;  4H0V A;  1R45 A;  4PKV A;  2WN8 A;  1GIR A;  1GY0 A;  4PKR A;  4FXQ A;  5DZQ A;  4ELN A;  3NTS A;  4TR5 A;  4XSG B;  2J3Z A;  2GWM A;  2J3X A;  3U0J A;  2C8G A;  1GXY A;  4XM6 A;  1G24 A;  2A9K B;  2GWL A;  4FML A;  1J7N A;  4GF1 A;  5H04 A;  4H0T A;  1GZF A;  2C8H A;  1R4B A;  5D1S A;  4XM8 A;  4FK7 A;  1OG4 A;  4PKQ A;  4XSH B;  1QS1 A;  1UZI A;  2BOV B;  4H0X A;  1OG3 A;  4PKU A;  1JKY A;  5D1U A;  2C8E E;  4WF6 A;  1PWP A;  1PWW A;  5BWM B;  2WN4 A;  1PWQ A;  4DV8 A;  1OG1 A;  2C89 A;  1OJQ A;  2J3V A;  2WN5 A;  4PKT A;  3BUZ A; 
#chains in the Genus database with same CATH homology
 2WN6 A;  5GTT A;  1YQY A;  4GY2 A;  1PWV A;  1GZE A;  5H03 A;  2C8C A;  1GIQ A;  1PWU A;  5D1T A;  1GXZ A;  4H0Y A;  4PKS A;  2C8A A;  2A78 B;  4XM7 A;  1OJZ A;  2C8F E;  4H03 A;  1QS2 A;  1ZXV A;  2WN7 A;  3BW8 A;  2C8B X;  2C8D A;  4PKW A;  4H0V A;  1R45 A;  4PKV A;  2WN8 A;  1GIR A;  1GY0 A;  4PKR A;  4FXQ A;  5DZQ A;  4ELN A;  3NTS A;  4TR5 A;  4XSG B;  2J3Z A;  2GWM A;  2J3X A;  3U0J A;  2C8G A;  1GXY A;  4XM6 A;  1G24 A;  2A9K B;  2GWL A;  4FML A;  1J7N A;  4GF1 A;  5H04 A;  4H0T A;  1GZF A;  2C8H A;  1R4B A;  5D1S A;  4XM8 A;  4FK7 A;  1OG4 A;  4PKQ A;  4XSH B;  1QS1 A;  1UZI A;  2BOV B;  4H0X A;  1OG3 A;  4PKU A;  1JKY A;  5D1U A;  2C8E E;  4WF6 A;  1PWP A;  1PWW A;  5BWM B;  2WN4 A;  1PWQ A;  4DV8 A;  1OG1 A;  2C89 A;  1OJQ A;  2J3V A;  2WN5 A;  4PKT A;  3BUZ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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