2C8FE

Structure of the artt motif e214n mutant c3bot1 exoenzyme (nad-bound state, crystal form iii)
Total Genus 61
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
61
sequence length
202
structure length
202
Chain Sequence
TYQEFTNIDQAKAWGNAQYKKYGLSKSEKEAIVSYTKSASEINGKLRQNKGVINGFPSNLIKQVELLDKSFNKMKTPENIMLFRGDDPAYLGTEFQNTLLNSNGTINKTAFEKAKAKFLNKDRLEYGYISTSLMNVSQFAGRPIITKFKVAKGSKAGYIDPISAFAGQLNMLLPRHSTYHIDDMRLSSDGKQIIITATMMGT
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title Structural Basis for the Nad-Hydrolysis Mechanism and the Artt-Loop Plasticity of C3 Exoenzymes.
pubmed doi rcsb
molecule keywords MONO-ADP-RIBOSYLTRANSFERASE C3
molecule tags Transferase
source organism Clostridium botulinum
total genus 61
structure length 202
sequence length 202
chains with identical sequence F, G
ec nomenclature ec 2.4.2.-:
pdb deposition date 2005-12-03
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.176.10 Alpha Beta Alpha-Beta Complex Toxin ADP-ribosyltransferase; Chain A, domain 1 Toxin ADP-ribosyltransferase; Chain A, domain 1 2c8fE00
2WN6A 2C8DA 2A78B 4GF1A 4H0VA 2C8EE 1OG4A 4TR5A 1ZXVA 1GIRA 2GWMA 5D1UA 4H0TA 3BW8A 4FXQA 4WF6A 1QS1A 1OJQA 4PKRA 2BOVB 1R45A 5H04A 5D1TA 5D1SA 1R4BA 3NTSA 1OG1A 1JKYA 4PKWA 4GY2A 1PWQA 4H03A 4H0YA 1PWUA 1UZIA 1PWPA 2C8CA 5DZQA 1OG3A 3BUZA 2WN4A 2C8GA 2J3XA 4FMLA 1GZFA 5GTTA 4PKSA 1GZEA 1QS2A 1GY0A 2J3VA 5BWMB 1GXZA 5H03A 2C8FE 1G24A 2GWLA 4H0XA 4PKTA 4PKQA 2J3ZA 2C89A 2C8BX 2WN5A 1GIQA 1PWVA 2A9KB 4PKVA 4DV8A 3U0JA 2C8AA 1GXYA 1YQYA 2C8HA 4PKUA 4ELNA 1PWWA 4XSGB 4XM8A 4XM6A 4XM7A 4FK7A 2WN7A 1J7NA 2WN8A 1OJZA 4XSHB
chains in the Genus database with same CATH superfamily
2WN6A 2C8DA 2A78B 4GF1A 4H0VA 2C8EE 1OG4A 4TR5A 1ZXVA 1GIRA 2GWMA 5D1UA 4H0TA 3BW8A 4FXQA 4WF6A 1QS1A 1OJQA 4PKRA 2BOVB 1R45A 5H04A 5D1TA 5D1SA 1R4BA 3NTSA 1OG1A 1JKYA 4PKWA 4GY2A 1PWQA 4H03A 4H0YA 1PWUA 1UZIA 1PWPA 2C8CA 5DZQA 1OG3A 3BUZA 2WN4A 2C8GA 2J3XA 4FMLA 1GZFA 5GTTA 4PKSA 1GZEA 1QS2A 1GY0A 2J3VA 5BWMB 1GXZA 5H03A 2C8FE 1G24A 2GWLA 4H0XA 4PKTA 4PKQA 2J3ZA 2C89A 2C8BX 2WN5A 1GIQA 1PWVA 2A9KB 4PKVA 4DV8A 3U0JA 2C8AA 1GXYA 1YQYA 2C8HA 4PKUA 4ELNA 1PWWA 4XSGB 4XM8A 4XM6A 4XM7A 4FK7A 2WN7A 1J7NA 2WN8A 1OJZA 4XSHB
chains in the Genus database with same CATH topology
2WN6A 2C8DA 2A78B 4GF1A 4H0VA 2C8EE 1OG4A 4TR5A 1ZXVA 1GIRA 2GWMA 5D1UA 4H0TA 3BW8A 4FXQA 4WF6A 1QS1A 1OJQA 4PKRA 2BOVB 1R45A 5H04A 5D1TA 5D1SA 1R4BA 3NTSA 1OG1A 1JKYA 4PKWA 4GY2A 1PWQA 4H03A 4H0YA 1PWUA 1UZIA 1PWPA 2C8CA 5DZQA 1OG3A 3BUZA 2WN4A 2C8GA 2J3XA 4FMLA 1GZFA 5GTTA 4PKSA 1GZEA 1QS2A 1GY0A 2J3VA 5BWMB 1GXZA 5H03A 2C8FE 1G24A 2GWLA 4H0XA 4PKTA 4PKQA 2J3ZA 2C89A 2C8BX 2WN5A 1GIQA 1PWVA 2A9KB 4PKVA 4DV8A 3U0JA 2C8AA 1GXYA 1YQYA 2C8HA 4PKUA 4ELNA 1PWWA 4XSGB 4XM8A 4XM6A 4XM7A 4FK7A 2WN7A 1J7NA 2WN8A 1OJZA 4XSHB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2WN6 A;  2C8D A;  2A78 B;  4GF1 A;  4H0V A;  2C8E E;  1OG4 A;  4TR5 A;  1ZXV A;  1GIR A;  2GWM A;  5D1U A;  4H0T A;  3BW8 A;  4FXQ A;  4WF6 A;  1QS1 A;  1OJQ A;  4PKR A;  2BOV B;  1R45 A;  5H04 A;  5D1T A;  5D1S A;  1R4B A;  3NTS A;  1OG1 A;  1JKY A;  4PKW A;  4GY2 A;  1PWQ A;  4H03 A;  4H0Y A;  1PWU A;  1UZI A;  1PWP A;  2C8C A;  5DZQ A;  1OG3 A;  3BUZ A;  2WN4 A;  2C8G A;  2J3X A;  4FML A;  1GZF A;  5GTT A;  4PKS A;  1GZE A;  1QS2 A;  1GY0 A;  2J3V A;  5BWM B;  1GXZ A;  5H03 A;  2C8F E;  1G24 A;  2GWL A;  4H0X A;  4PKT A;  4PKQ A;  2J3Z A;  2C89 A;  2C8B X;  2WN5 A;  1GIQ A;  1PWV A;  2A9K B;  4PKV A;  4DV8 A;  3U0J A;  2C8A A;  1GXY A;  1YQY A;  2C8H A;  4PKU A;  4ELN A;  1PWW A;  4XSG B;  4XM8 A;  4XM6 A;  4XM7 A;  4FK7 A;  2WN7 A;  1J7N A;  2WN8 A;  1OJZ A;  4XSH B; 
#chains in the Genus database with same CATH topology
 2WN6 A;  2C8D A;  2A78 B;  4GF1 A;  4H0V A;  2C8E E;  1OG4 A;  4TR5 A;  1ZXV A;  1GIR A;  2GWM A;  5D1U A;  4H0T A;  3BW8 A;  4FXQ A;  4WF6 A;  1QS1 A;  1OJQ A;  4PKR A;  2BOV B;  1R45 A;  5H04 A;  5D1T A;  5D1S A;  1R4B A;  3NTS A;  1OG1 A;  1JKY A;  4PKW A;  4GY2 A;  1PWQ A;  4H03 A;  4H0Y A;  1PWU A;  1UZI A;  1PWP A;  2C8C A;  5DZQ A;  1OG3 A;  3BUZ A;  2WN4 A;  2C8G A;  2J3X A;  4FML A;  1GZF A;  5GTT A;  4PKS A;  1GZE A;  1QS2 A;  1GY0 A;  2J3V A;  5BWM B;  1GXZ A;  5H03 A;  2C8F E;  1G24 A;  2GWL A;  4H0X A;  4PKT A;  4PKQ A;  2J3Z A;  2C89 A;  2C8B X;  2WN5 A;  1GIQ A;  1PWV A;  2A9K B;  4PKV A;  4DV8 A;  3U0J A;  2C8A A;  1GXY A;  1YQY A;  2C8H A;  4PKU A;  4ELN A;  1PWW A;  4XSG B;  4XM8 A;  4XM6 A;  4XM7 A;  4FK7 A;  2WN7 A;  1J7N A;  2WN8 A;  1OJZ A;  4XSH B; 
#chains in the Genus database with same CATH homology
 2WN6 A;  2C8D A;  2A78 B;  4GF1 A;  4H0V A;  2C8E E;  1OG4 A;  4TR5 A;  1ZXV A;  1GIR A;  2GWM A;  5D1U A;  4H0T A;  3BW8 A;  4FXQ A;  4WF6 A;  1QS1 A;  1OJQ A;  4PKR A;  2BOV B;  1R45 A;  5H04 A;  5D1T A;  5D1S A;  1R4B A;  3NTS A;  1OG1 A;  1JKY A;  4PKW A;  4GY2 A;  1PWQ A;  4H03 A;  4H0Y A;  1PWU A;  1UZI A;  1PWP A;  2C8C A;  5DZQ A;  1OG3 A;  3BUZ A;  2WN4 A;  2C8G A;  2J3X A;  4FML A;  1GZF A;  5GTT A;  4PKS A;  1GZE A;  1QS2 A;  1GY0 A;  2J3V A;  5BWM B;  1GXZ A;  5H03 A;  2C8F E;  1G24 A;  2GWL A;  4H0X A;  4PKT A;  4PKQ A;  2J3Z A;  2C89 A;  2C8B X;  2WN5 A;  1GIQ A;  1PWV A;  2A9K B;  4PKV A;  4DV8 A;  3U0J A;  2C8A A;  1GXY A;  1YQY A;  2C8H A;  4PKU A;  4ELN A;  1PWW A;  4XSG B;  4XM8 A;  4XM6 A;  4XM7 A;  4FK7 A;  2WN7 A;  1J7N A;  2WN8 A;  1OJZ A;  4XSH B; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...