2CG5B

Structure of aminoadipate-semialdehyde dehydrogenase- phosphopantetheinyl transferase in complex with cytosolic acyl carrier protein and coenzyme a
Total Genus 19
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
19
sequence length
71
structure length
71
Chain Sequence
b'QRDLVEAVAHILGIRDLAAVNLDSSLADLGLDALMSVEVRQTLERELNLVLSVREVRQLTLRKLQELSSKA'
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule keywords L-AMINOADIPATE-SEMIALDEHYDE DEHYDROGENASE-PHOSPHOPANTETHEINY
publication title Mechanism and Substrate Recognition of Human Holo Acp Synthase.
pubmed doi rcsb
source organism Homo sapiens
molecule tags Transferase/hydrolase
total genus 19
structure length 71
sequence length 71
ec nomenclature ec 1.1.1.100: 3-oxoacyl-[acyl-carrier-protein] reductase.
pdb deposition date 2006-02-27

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF00550 PP-binding Phosphopantetheine attachment site
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1200.10 Mainly Alpha Orthogonal Bundle Non-ribosomal Peptide Synthetase Peptidyl Carrier Protein; Chain A ACP-like 2cg5B00
2DNWA 2VSQA 2MR7A 3GZLA 2LIUA 2AFDA 2N6ZA 4DG9A 1L0HA 2L0QA 4NEOA 2FQ1A 2GDXA 4MRTC 4H2YC 5KP6B 5KP7B 4CA3A 2N5IA 1ACPA 2LKIA 4IZ6A 4PXHB 2KWLA 2N6YA 2JQ4A 2MF4A 2MR8A 1DV5A 2KOPA 1NQ4A 2AFEA 2AF8A 5EJDA 2K94A 2LPKA 2X2BA 4PWVB 4BPGA 2K2QA 2GDWA 2GDYA 1HY8A 4BPHA 2CGQA 2KGAA 2KORA 2KG9A 4H2XC 2M5RA 2FVFA 3LMOA 2JU2A 2EHSA 2KOOA 2K0YA 2QNWA 3CE7A 4R0MA 2FACA 2MVVA 2KG6A 2LL8A 2ROQA 4H2WC 2JU1A 2L9FA 2L22A 3EJBA 4HKGA 2CQ8A 2CG5B 2L4BA 2LTEA 2N5HA 5HVCA 2KR5A 3NY7B 2N50A 3EJEA 1F80D 1T8KA 2PNGA 2N98A 2LMLA 2JGPA 2KG8A 2FADA 2LOLA 3RG2A 2LIWA 5HV8A 2FQ0A 1HQBA 2KOSA 2MVUA 2MY5A 2KOQA 2XZ0D 2FVAA 2FHSC 3EJDA 2K92A 2XZ1C 5KP8B 2MD9A 5CZDB 2EHTA 2KW2A 1OR5A 2K0XA 1X3OA 2KGDA 1DNYA 2KGEA 2FVEA 2K93A 2CNRA 1AF8A 2AVAA 4BPFA 1KLPA 2KGCA 1VKUA 2FQ2A 3GZMA 2FAEA 1L0IA
chains in the Genus database with same CATH superfamily
2LIUA 4DG9A 3B5IA 1ZMBA 4XROA 5KP7B 1YITP 3CD6P 1VQ8P 2GYKA 1ACPA 4IZ6A 4PXHB 4U0AA 2N6YA 3CCJP 5HGNA 2MF4A 1GXGA 1VQ9P 1DV5A 5EJDA 2K94A 3H47A 1E0HA 2EIAA 2X2BA 3CCRP 3DTJA 4QNBA 2GDWA 3G26A 3DS3A 4M0IA 2KGAA 3G1GA 2FVFA 2JAZA 2GZGA 3CCEP 1RNIA 2PENA 1M74A 2JYGA 2CWOA 1Z6MA 2FACA 2KG6A 2LL8A 2JU1A 1EIAA 7CEIA 4HKGA 1VQ6P 2LTEA 2CG5B 2KR5A 1YJNP 5HGMA 4U0DA 3P05A 3EJEA 2LOLA 3RG2A 3CCVP 1KD1Q 1VQPP 4XFXA 1ZNVA 2MVUA 1GPJA 2VLQA 3EJDA 2PEOA 3G28A 1M6EX 2M8LA 1N8RQ 1OR5A 3G1IA 2K0XA 2OTJP 2GZJA 3GKLC 3LRYA 3NTEA 5F2NA 1UJZA 3G4SP 1IMPA 1AF8A 3HZQA 4BPFA 3HYBA 1Q86Q 5F2KA 1D1DA 1NJIQ 2DNWA 3CPWO 2VSQA 3GZLA 2N6ZA 2AFDA 1VQOP 2NO8A 2FQ1A 2GDXA 4H2YC 3CMEP 3DS5A 3MGEA 4CA3A 2N5IA 2ONTA 4GR6A 3GJNA 3CCUP 2JQ4A 2Z44A 2ERHA 1S72P 4WYMA 2GZEA 5EW5E 1VQ5P 2QEXP 5HGLA 4BPHA 2CGQA 1IUQA 4COPA 4UHPB 1YIJP 2KORA 1K9MQ 2XV6A 2JU2A 3I56P 3VRLC 1JJ2O 2MVVA 1KQSO 5BS2A 2L4BA 3I55P 2PEIA 2PNGA 2JGPA 2FADA 1K30A 2VLPA 2FQ0A 1VHNA 4U0FA 2KOQA 5CZDB 2MD9A 1M90Q 4XFZA 2EHTA 1YI2P 4COCA 2KW2A 2KGDA 4GR2A 2KGEA 4XFYA 2M8PA 2K5XA 2JBGA 2Z45A 4U0BA 2L6EA 2LF4A 2EFJA 3WBHA 2QA4P 2JYLA 3CCSP 3H0DA 2XT1A 1L0HA 3DS4A 4NEOA 2JB0A 4MRTC 5KP6B 2LKIA 3CC7P 1AUMA 2KOPA 2AFEA 3G71P 1YJWP 2WPTA 4BPGA 1YHQP 2GDYA 1HY8A 3CC2P 1VQLP 1FR2A 4F37A 2M5RA 3LMOA 1A8OA 3B4QA 2DGYA 2K0DX 3E2DA 2EHSA 2KOOA 1Q82Q 2JO0A 2ROQA 3DPHA 5HVCA 1F80D 1RO0A 1T8KA 3G21A 1A43A 2N98A 2LMLA 3G29A 3G0VA 2LIWA 5HV8A 2KOSA 2FVAA 2VLOA 2K92A 5KP8B 2Z46A 2XXMA 1EOQA 1VQ4P 4PH0A 2M8NA 1MZ8A 4U0EA 1VQNP 1X3OA 3OW2O 5I4TG 5F2OA 2OTLP 1W2BO 2FVEA 2K93A 1K8AQ 2CNRA 2AVAA 4PH1A 1QVGO 2KGCA 1E6JP 1M6NA 1VKUA 2FQ2A 2FAEA 3M1MA 3CMAP 2MR7A 5DCKA 2GZFA 1K73Q 2L0QA 4IPYA 1Q7YQ 3U43A 2KODA 1IMQA 1AYIA 1Q81Q 5JPAA 2E1MA 5BS1A 2KWLA 2MR8A 3DS2A 1NQ4A 1VQKP 2AF8A 1QRJA 3CC4P 2P9XA 2LPKA 4PWVB 2K2QA 2GZIA 1VQ7P 1QVFO 1UNKA 1VQMP 1BXIA 3Q20A 2KG9A 2BHVA 2BUOA 4H2XC 4XRQA 1RO2A 1BAJA 1CEIA 3RG6C 2K0YA 2QNWA 3CE7A 2PEJA 4R0MA 1EMVA 4H2WC 1GXHA 2L9FA 2L22A 3EJBA 2CQ8A 2N5HA 3NY7B 2N50A 2PY8A 2VLNA 2KG8A 3CCMP 3CCLP 1HQBA 4QKOA 3DS1A 2MY5A 2XZ0D 2EG5A 2FHSC 2PEKA 2XZ1C 1YJ9P 2OARA 2PEQA 3H4EA 5HGOA 2PEMA 1KC8Q 1DNYA 3DS0A 1M1KQ 3G6EP 4U0CA 1KLPA 3GZMA 3CXCO 1L0IA 3CCQP
chains in the Genus database with same CATH topology
2DNWA 2VSQA 2MR7A 3GZLA 2LIUA 2AFDA 2N6ZA 4DG9A 1L0HA 2L0QA 4NEOA 2FQ1A 2GDXA 4MRTC 4H2YC 5KP6B 5KP7B 4CA3A 2N5IA 1ACPA 2LKIA 4IZ6A 4PXHB 2KWLA 2N6YA 2JQ4A 2MF4A 2MR8A 1DV5A 2KOPA 1NQ4A 2AFEA 2AF8A 5EJDA 2K94A 2LPKA 2X2BA 4PWVB 4BPGA 2K2QA 2GDWA 2GDYA 1HY8A 4BPHA 2CGQA 2KGAA 2KORA 2KG9A 4H2XC 2M5RA 2FVFA 3LMOA 2JU2A 2EHSA 2KOOA 2K0YA 2QNWA 3CE7A 4R0MA 2FACA 2MVVA 2KG6A 2LL8A 2ROQA 4H2WC 2JU1A 2L9FA 2L22A 3EJBA 4HKGA 2CQ8A 2CG5B 2L4BA 2LTEA 2N5HA 5HVCA 2KR5A 3NY7B 2N50A 3EJEA 1F80D 1T8KA 2PNGA 2N98A 2LMLA 2JGPA 2KG8A 2FADA 2LOLA 3RG2A 2LIWA 5HV8A 2FQ0A 1HQBA 2KOSA 2MVUA 2MY5A 2KOQA 2XZ0D 2FVAA 2FHSC 3EJDA 2K92A 2XZ1C 5KP8B 2MD9A 5CZDB 2EHTA 2KW2A 1OR5A 2K0XA 1X3OA 2KGDA 1DNYA 2KGEA 2FVEA 2K93A 2CNRA 1AF8A 2AVAA 4BPFA 1KLPA 2KGCA 1VKUA 2FQ2A 3GZMA 2FAEA 1L0IA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2DNW A;  2VSQ A;  2MR7 A;  3GZL A;  2LIU A;  2AFD A;  2N6Z A;  4DG9 A;  1L0H A;  2L0Q A;  4NEO A;  2FQ1 A;  2GDX A;  4MRT C;  4H2Y C;  5KP6 B;  5KP7 B;  4CA3 A;  2N5I A;  1ACP A;  2LKI A;  4IZ6 A;  4PXH B;  2KWL A;  2N6Y A;  2JQ4 A;  2MF4 A;  2MR8 A;  1DV5 A;  2KOP A;  1NQ4 A;  2AFE A;  2AF8 A;  5EJD A;  2K94 A;  2LPK A;  2X2B A;  4PWV B;  4BPG A;  2K2Q A;  2GDW A;  2GDY A;  1HY8 A;  4BPH A;  2CGQ A;  2KGA A;  2KOR A;  2KG9 A;  4H2X C;  2M5R A;  2FVF A;  3LMO A;  2JU2 A;  2EHS A;  2KOO A;  2K0Y A;  2QNW A;  3CE7 A;  4R0M A;  2FAC A;  2MVV A;  2KG6 A;  2LL8 A;  2ROQ A;  4H2W C;  2JU1 A;  2L9F A;  2L22 A;  3EJB A;  4HKG A;  2CQ8 A;  2CG5 B;  2L4B A;  2LTE A;  2N5H A;  5HVC A;  2KR5 A;  3NY7 B;  2N50 A;  3EJE A;  1F80 D;  1T8K A;  2PNG A;  2N98 A;  2LML A;  2JGP A;  2KG8 A;  2FAD A;  2LOL A;  3RG2 A;  2LIW A;  5HV8 A;  2FQ0 A;  1HQB A;  2KOS A;  2MVU A;  2MY5 A;  2KOQ A;  2XZ0 D;  2FVA A;  2FHS C;  3EJD A;  2K92 A;  2XZ1 C;  5KP8 B;  2MD9 A;  5CZD B;  2EHT A;  2KW2 A;  1OR5 A;  2K0X A;  1X3O A;  2KGD A;  1DNY A;  2KGE A;  2FVE A;  2K93 A;  2CNR A;  1AF8 A;  2AVA A;  4BPF A;  1KLP A;  2KGC A;  1VKU A;  2FQ2 A;  3GZM A;  2FAE A;  1L0I A; 
#chains in the Genus database with same CATH topology
 2LIU A;  4DG9 A;  3B5I A;  1ZMB A;  4XRO A;  5KP7 B;  1YIT P;  3CD6 P;  1VQ8 P;  2GYK A;  1ACP A;  4IZ6 A;  4PXH B;  4U0A A;  2N6Y A;  3CCJ P;  5HGN A;  2MF4 A;  1GXG A;  1VQ9 P;  1DV5 A;  5EJD A;  2K94 A;  3H47 A;  1E0H A;  2EIA A;  2X2B A;  3CCR P;  3DTJ A;  4QNB A;  2GDW A;  3G26 A;  3DS3 A;  4M0I A;  2KGA A;  3G1G A;  2FVF A;  2JAZ A;  2GZG A;  3CCE P;  1RNI A;  2PEN A;  1M74 A;  2JYG A;  2CWO A;  1Z6M A;  2FAC A;  2KG6 A;  2LL8 A;  2JU1 A;  1EIA A;  7CEI A;  4HKG A;  1VQ6 P;  2LTE A;  2CG5 B;  2KR5 A;  1YJN P;  5HGM A;  4U0D A;  3P05 A;  3EJE A;  2LOL A;  3RG2 A;  3CCV P;  1KD1 Q;  1VQP P;  4XFX A;  1ZNV A;  2MVU A;  1GPJ A;  2VLQ A;  3EJD A;  2PEO A;  3G28 A;  1M6E X;  2M8L A;  1N8R Q;  1OR5 A;  3G1I A;  2K0X A;  2OTJ P;  2GZJ A;  3GKL C;  3LRY A;  3NTE A;  5F2N A;  1UJZ A;  3G4S P;  1IMP A;  1AF8 A;  3HZQ A;  4BPF A;  3HYB A;  1Q86 Q;  5F2K A;  1D1D A;  1NJI Q;  2DNW A;  3CPW O;  2VSQ A;  3GZL A;  2N6Z A;  2AFD A;  1VQO P;  2NO8 A;  2FQ1 A;  2GDX A;  4H2Y C;  3CME P;  3DS5 A;  3MGE A;  4CA3 A;  2N5I A;  2ONT A;  4GR6 A;  3GJN A;  3CCU P;  2JQ4 A;  2Z44 A;  2ERH A;  1S72 P;  4WYM A;  2GZE A;  5EW5 E;  1VQ5 P;  2QEX P;  5HGL A;  4BPH A;  2CGQ A;  1IUQ A;  4COP A;  4UHP B;  1YIJ P;  2KOR A;  1K9M Q;  2XV6 A;  2JU2 A;  3I56 P;  3VRL C;  1JJ2 O;  2MVV A;  1KQS O;  5BS2 A;  2L4B A;  3I55 P;  2PEI A;  2PNG A;  2JGP A;  2FAD A;  1K30 A;  2VLP A;  2FQ0 A;  1VHN A;  4U0F A;  2KOQ A;  5CZD B;  2MD9 A;  1M90 Q;  4XFZ A;  2EHT A;  1YI2 P;  4COC A;  2KW2 A;  2KGD A;  4GR2 A;  2KGE A;  4XFY A;  2M8P A;  2K5X A;  2JBG A;  2Z45 A;  4U0B A;  2L6E A;  2LF4 A;  2EFJ A;  3WBH A;  2QA4 P;  2JYL A;  3CCS P;  3H0D A;  2XT1 A;  1L0H A;  3DS4 A;  4NEO A;  2JB0 A;  4MRT C;  5KP6 B;  2LKI A;  3CC7 P;  1AUM A;  2KOP A;  2AFE A;  3G71 P;  1YJW P;  2WPT A;  4BPG A;  1YHQ P;  2GDY A;  1HY8 A;  3CC2 P;  1VQL P;  1FR2 A;  4F37 A;  2M5R A;  3LMO A;  1A8O A;  3B4Q A;  2DGY A;  2K0D X;  3E2D A;  2EHS A;  2KOO A;  1Q82 Q;  2JO0 A;  2ROQ A;  3DPH A;  5HVC A;  1F80 D;  1RO0 A;  1T8K A;  3G21 A;  1A43 A;  2N98 A;  2LML A;  3G29 A;  3G0V A;  2LIW A;  5HV8 A;  2KOS A;  2FVA A;  2VLO A;  2K92 A;  5KP8 B;  2Z46 A;  2XXM A;  1EOQ A;  1VQ4 P;  4PH0 A;  2M8N A;  1MZ8 A;  4U0E A;  1VQN P;  1X3O A;  3OW2 O;  5I4T G;  5F2O A;  2OTL P;  1W2B O;  2FVE A;  2K93 A;  1K8A Q;  2CNR A;  2AVA A;  4PH1 A;  1QVG O;  2KGC A;  1E6J P;  1M6N A;  1VKU A;  2FQ2 A;  2FAE A;  3M1M A;  3CMA P;  2MR7 A;  5DCK A;  2GZF A;  1K73 Q;  2L0Q A;  4IPY A;  1Q7Y Q;  3U43 A;  2KOD A;  1IMQ A;  1AYI A;  1Q81 Q;  5JPA A;  2E1M A;  5BS1 A;  2KWL A;  2MR8 A;  3DS2 A;  1NQ4 A;  1VQK P;  2AF8 A;  1QRJ A;  3CC4 P;  2P9X A;  2LPK A;  4PWV B;  2K2Q A;  2GZI A;  1VQ7 P;  1QVF O;  1UNK A;  1VQM P;  1BXI A;  3Q20 A;  2KG9 A;  2BHV A;  2BUO A;  4H2X C;  4XRQ A;  1RO2 A;  1BAJ A;  1CEI A;  3RG6 C;  2K0Y A;  2QNW A;  3CE7 A;  2PEJ A;  4R0M A;  1EMV A;  4H2W C;  1GXH A;  2L9F A;  2L22 A;  3EJB A;  2CQ8 A;  2N5H A;  3NY7 B;  2N50 A;  2PY8 A;  2VLN A;  2KG8 A;  3CCM P;  3CCL P;  1HQB A;  4QKO A;  3DS1 A;  2MY5 A;  2XZ0 D;  2EG5 A;  2FHS C;  2PEK A;  2XZ1 C;  1YJ9 P;  2OAR A;  2PEQ A;  3H4E A;  5HGO A;  2PEM A;  1KC8 Q;  1DNY A;  3DS0 A;  1M1K Q;  3G6E P;  4U0C A;  1KLP A;  3GZM A;  3CXC O;  1L0I A;  3CCQ P; 
#chains in the Genus database with same CATH homology
 2DNW A;  2VSQ A;  2MR7 A;  3GZL A;  2LIU A;  2AFD A;  2N6Z A;  4DG9 A;  1L0H A;  2L0Q A;  4NEO A;  2FQ1 A;  2GDX A;  4MRT C;  4H2Y C;  5KP6 B;  5KP7 B;  4CA3 A;  2N5I A;  1ACP A;  2LKI A;  4IZ6 A;  4PXH B;  2KWL A;  2N6Y A;  2JQ4 A;  2MF4 A;  2MR8 A;  1DV5 A;  2KOP A;  1NQ4 A;  2AFE A;  2AF8 A;  5EJD A;  2K94 A;  2LPK A;  2X2B A;  4PWV B;  4BPG A;  2K2Q A;  2GDW A;  2GDY A;  1HY8 A;  4BPH A;  2CGQ A;  2KGA A;  2KOR A;  2KG9 A;  4H2X C;  2M5R A;  2FVF A;  3LMO A;  2JU2 A;  2EHS A;  2KOO A;  2K0Y A;  2QNW A;  3CE7 A;  4R0M A;  2FAC A;  2MVV A;  2KG6 A;  2LL8 A;  2ROQ A;  4H2W C;  2JU1 A;  2L9F A;  2L22 A;  3EJB A;  4HKG A;  2CQ8 A;  2CG5 B;  2L4B A;  2LTE A;  2N5H A;  5HVC A;  2KR5 A;  3NY7 B;  2N50 A;  3EJE A;  1F80 D;  1T8K A;  2PNG A;  2N98 A;  2LML A;  2JGP A;  2KG8 A;  2FAD A;  2LOL A;  3RG2 A;  2LIW A;  5HV8 A;  2FQ0 A;  1HQB A;  2KOS A;  2MVU A;  2MY5 A;  2KOQ A;  2XZ0 D;  2FVA A;  2FHS C;  3EJD A;  2K92 A;  2XZ1 C;  5KP8 B;  2MD9 A;  5CZD B;  2EHT A;  2KW2 A;  1OR5 A;  2K0X A;  1X3O A;  2KGD A;  1DNY A;  2KGE A;  2FVE A;  2K93 A;  2CNR A;  1AF8 A;  2AVA A;  4BPF A;  1KLP A;  2KGC A;  1VKU A;  2FQ2 A;  3GZM A;  2FAE A;  1L0I A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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