2CG5B

Structure of aminoadipate-semialdehyde dehydrogenase- phosphopantetheinyl transferase in complex with cytosolic acyl carrier protein and coenzyme a
Total Genus 19
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
19
sequence length
71
structure length
71
Chain Sequence
QRDLVEAVAHILGIRDLAAVNLDSSLADLGLDALMSVEVRQTLERELNLVLSVREVRQLTLRKLQELSSKA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule keywords L-AMINOADIPATE-SEMIALDEHYDE DEHYDROGENASE-PHOSPHOPANTETHEINY
publication title Mechanism and Substrate Recognition of Human Holo Acp Synthase.
pubmed doi rcsb
source organism Homo sapiens
molecule tags Transferase/hydrolase
total genus 19
structure length 71
sequence length 71
ec nomenclature ec 1.1.1.100: 3-oxoacyl-[acyl-carrier-protein] reductase.
pdb deposition date 2006-02-27

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF00550 PP-binding Phosphopantetheine attachment site
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1200.10 Mainly Alpha Orthogonal Bundle Non-ribosomal Peptide Synthetase Peptidyl Carrier Protein; Chain A ACP-like 2cg5B00
2GDXA 1L0IA 2N6ZA 2N6YA 2KWLA 5HV8A 2AFDA 1DV5A 2LPKA 2QNWA 1KLPA 1X3OA 2EHTA 2LKIA 2FQ2A 2KR5A 2K92A 4H2YC 2MVUA 5HVCA 1NQ4A 4BPHA 2L0QA 2KGAA 3LMOA 2MR8A 1HQBA 2KG9A 4BPGA 2KG8A 5EJDA 1ACPA 3EJBA 3GZLA 1F80D 2K93A 2M5RA 2L4BA 2FACA 2LL8A 2CQ8A 2FAEA 1L0HA 5KP7B 4NEOA 3NY7B 4IZ6A 2K0XA 2N98A 2JGPA 4MRTC 4DG9A 2KOOA 2MD9A 2DNWA 2LMLA 2CGQA 2KGCA 1AF8A 4H2WC 2KG6A 2FQ1A 2CNRA 2LIUA 1DNYA 2GDWA 3CE7A 2N5HA 2K94A 4H2XC 2N50A 2XZ0D 2LTEA 2LIWA 2KORA 2KGEA 2FHSC 4PWVB 2JU1A 2PNGA 1OR5A 2X2BA 3EJEA 2EHSA 2K0YA 2N5IA 2KOQA 2JQ4A 2KW2A 4HKGA 2AF8A 3EJDA 4CA3A 2GDYA 2JU2A 4R0MA 4BPFA 2FQ0A 2CG5B 2MR7A 1T8KA 5KP6B 2FVFA 2KGDA 5CZDB 2L22A 4PXHB 2LOLA 2MVVA 3RG2A 2L9FA 2FVEA 2KOPA 1VKUA 2XZ1C 2AFEA 2FADA 2KOSA 2MY5A 5KP8B 3GZMA 2VSQA 1HY8A 2FVAA 2MF4A 2ROQA 2AVAA 2K2QA
chains in the Genus database with same CATH superfamily
1VQNP 1A8OA 3CMEP 2LPKA 1UNKA 2EHTA 1YI2P 2LKIA 4XROA 5JPAA 1Z6MA 1GXGA 4H2YC 2MVUA 2XV6A 4BPHA 1K8AQ 1Q7YQ 1HQBA 4BPGA 2KG8A 1ACPA 2PEQA 3GZLA 3HZQA 4IPYA 2XT1A 2P9XA 1VQ8P 2PEKA 2BUOA 4IZ6A 2VLQA 3CXCO 2KGCA 1AF8A 3CCQP 2GDWA 3CE7A 3CC7P 2CWOA 1YIJP 1YJNP 1KC8Q 4PWVB 3CD6P 1AYIA 3EJEA 2K0YA 3G71P 4HKGA 1IMQA 3EJDA 1Q81Q 2Z45A 1VQ4P 3U43A 2PEMA 2GYKA 2Z46A 2FVFA 1VQPP 1YITP 2LOLA 2FVEA 2KOPA 1GXHA 3B4QA 2KOSA 2MY5A 4XRQA 3GZMA 2FVAA 2PENA 4U0DA 2MF4A 2K0DX 1Q82Q 2M8NA 5F2OA 1L0IA 2JB0A 2N6YA 1UJZA 2GZIA 2Z44A 2ONTA 2FQ2A 4U0CA 4XFYA 2EG5A 2KODA 1QRJA 5HVCA 2E1MA 1MZ8A 2VLOA 3LMOA 3RG6C 1VQ9P 3EJBA 1AUMA 4UHPB 1EMVA 2M5RA 3GKLC 3G26A 1FR2A 1NJIQ 5F2NA 5KP7B 4NEOA 3G0VA 3NY7B 4XFZA 3Q20A 3OW2O 2GZJA 1A43A 2JAZA 4H2WC 1S72P 1CEIA 3DS0A 2N5HA 2K94A 4COCA 3G1GA 1K73Q 2LTEA 5HGLA 3CCVP 3VRLC 2KGEA 4U0EA 1K9MQ 2PNGA 3CCEP 2KOQA 5F2KA 3CCJP 2AF8A 1K30A 2GZEA 2GDYA 2JYGA 4BPFA 2FQ0A 4GR2A 2CG5B 2PEIA 2MR7A 2KGDA 5CZDB 4PXHB 1EOQA 2L9FA 1ZMBA 2XZ1C 2M8PA 2FADA 1IMPA 5KP8B 2ERHA 5HGOA 1N8RQ 2JO0A 1EIAA 2N6ZA 2KWLA 3G6EP 3CCSP 2KR5A 2OARA 3CCUP 2BHVA 1VQKP 5EW5E 1VQ5P 1M1KQ 1E0HA 3GJNA 3G29A 2L0QA 2DGYA 2PEOA 3G28A 4U0FA 5BS1A 2K93A 1QVGO 2L4BA 4PH1A 1JJ2O 2JYLA 3CCLP 2LL8A 2CQ8A 2M8LA 2VLNA 1L0HA 1E6JP 1GPJA 2LF4A 2EIAA 1D1DA 2N98A 2JGPA 4MRTC 4DG9A 2KOOA 3DS4A 2CGQA 3CPWO 2KG6A 2FQ1A 2CNRA 2LIUA 1RO2A 3DS1A 4U0AA 3DS2A 1DNYA 1VQLP 2QEXP 4H2XC 2N50A 2XZ0D 1BAJA 5HGMA 2QA4P 2XXMA 3CC4P 4F37A 2KORA 4WYMA 3CCMP 3CCRP 2JU1A 4QNBA 1OR5A 2X2BA 1VQOP 2WPTA 1VQ7P 1VQ6P 3H0DA 3HYBA 4CA3A 2EFJA 4QKOA 1VQMP 4GR6A 3G4SP 1KD1Q 1ZNVA 3MGEA 3RG2A 1BXIA 1VKUA 3CMAP 1HY8A 3G21A 2PY8A 3DPHA 1M74A 5BS2A 2ROQA 2AVAA 1QVFO 5I4TG 1RNIA 5DCKA 2GDXA 2K5XA 2JBGA 3DS5A 5HV8A 2AFDA 1KQSO 1DV5A 2QNWA 1KLPA 1X3OA 4COPA 2K92A 4XFXA 1NQ4A 3G1IA 2GZGA 2OTLP 2KGAA 2MR8A 2KG9A 1IUQA 1M6EX 5EJDA 1Q86Q 3H4EA 1F80D 2NO8A 1YHQP 2FACA 3E2DA 3I56P 3P05A 2FAEA 2K0XA 1W2BO 3M1MA 2OTJP 2MD9A 3CC2P 2DNWA 2LMLA 4PH0A 2VLPA 7CEIA 3DS3A 2PEJA 1VHNA 3NTEA 3I55P 4U0BA 2LIWA 1YJ9P 3B5IA 2L6EA 2FHSC 3H47A 1M90Q 2EHSA 2N5IA 2JQ4A 2KW2A 4R0MA 2JU2A 1YJWP 3LRYA 1T8KA 1M6NA 5KP6B 2L22A 2MVVA 4M0IA 3WBHA 2AFEA 5HGNA 1RO0A 2VSQA 2GZFA 3DTJA 2K2QA
chains in the Genus database with same CATH topology
2GDXA 1L0IA 2N6ZA 2N6YA 2KWLA 5HV8A 2AFDA 1DV5A 2LPKA 2QNWA 1KLPA 1X3OA 2EHTA 2LKIA 2FQ2A 2KR5A 2K92A 4H2YC 2MVUA 5HVCA 1NQ4A 4BPHA 2L0QA 2KGAA 3LMOA 2MR8A 1HQBA 2KG9A 4BPGA 2KG8A 5EJDA 1ACPA 3EJBA 3GZLA 1F80D 2K93A 2M5RA 2L4BA 2FACA 2LL8A 2CQ8A 2FAEA 1L0HA 5KP7B 4NEOA 3NY7B 4IZ6A 2K0XA 2N98A 2JGPA 4MRTC 4DG9A 2KOOA 2MD9A 2DNWA 2LMLA 2CGQA 2KGCA 1AF8A 4H2WC 2KG6A 2FQ1A 2CNRA 2LIUA 1DNYA 2GDWA 3CE7A 2N5HA 2K94A 4H2XC 2N50A 2XZ0D 2LTEA 2LIWA 2KORA 2KGEA 2FHSC 4PWVB 2JU1A 2PNGA 1OR5A 2X2BA 3EJEA 2EHSA 2K0YA 2N5IA 2KOQA 2JQ4A 2KW2A 4HKGA 2AF8A 3EJDA 4CA3A 2GDYA 2JU2A 4R0MA 4BPFA 2FQ0A 2CG5B 2MR7A 1T8KA 5KP6B 2FVFA 2KGDA 5CZDB 2L22A 4PXHB 2LOLA 2MVVA 3RG2A 2L9FA 2FVEA 2KOPA 1VKUA 2XZ1C 2AFEA 2FADA 2KOSA 2MY5A 5KP8B 3GZMA 2VSQA 1HY8A 2FVAA 2MF4A 2ROQA 2AVAA 2K2QA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2GDX A;  1L0I A;  2N6Z A;  2N6Y A;  2KWL A;  5HV8 A;  2AFD A;  1DV5 A;  2LPK A;  2QNW A;  1KLP A;  1X3O A;  2EHT A;  2LKI A;  2FQ2 A;  2KR5 A;  2K92 A;  4H2Y C;  2MVU A;  5HVC A;  1NQ4 A;  4BPH A;  2L0Q A;  2KGA A;  3LMO A;  2MR8 A;  1HQB A;  2KG9 A;  4BPG A;  2KG8 A;  5EJD A;  1ACP A;  3EJB A;  3GZL A;  1F80 D;  2K93 A;  2M5R A;  2L4B A;  2FAC A;  2LL8 A;  2CQ8 A;  2FAE A;  1L0H A;  5KP7 B;  4NEO A;  3NY7 B;  4IZ6 A;  2K0X A;  2N98 A;  2JGP A;  4MRT C;  4DG9 A;  2KOO A;  2MD9 A;  2DNW A;  2LML A;  2CGQ A;  2KGC A;  1AF8 A;  4H2W C;  2KG6 A;  2FQ1 A;  2CNR A;  2LIU A;  1DNY A;  2GDW A;  3CE7 A;  2N5H A;  2K94 A;  4H2X C;  2N50 A;  2XZ0 D;  2LTE A;  2LIW A;  2KOR A;  2KGE A;  2FHS C;  4PWV B;  2JU1 A;  2PNG A;  1OR5 A;  2X2B A;  3EJE A;  2EHS A;  2K0Y A;  2N5I A;  2KOQ A;  2JQ4 A;  2KW2 A;  4HKG A;  2AF8 A;  3EJD A;  4CA3 A;  2GDY A;  2JU2 A;  4R0M A;  4BPF A;  2FQ0 A;  2CG5 B;  2MR7 A;  1T8K A;  5KP6 B;  2FVF A;  2KGD A;  5CZD B;  2L22 A;  4PXH B;  2LOL A;  2MVV A;  3RG2 A;  2L9F A;  2FVE A;  2KOP A;  1VKU A;  2XZ1 C;  2AFE A;  2FAD A;  2KOS A;  2MY5 A;  5KP8 B;  3GZM A;  2VSQ A;  1HY8 A;  2FVA A;  2MF4 A;  2ROQ A;  2AVA A;  2K2Q A; 
#chains in the Genus database with same CATH topology
 1VQN P;  1A8O A;  3CME P;  2LPK A;  1UNK A;  2EHT A;  1YI2 P;  2LKI A;  4XRO A;  5JPA A;  1Z6M A;  1GXG A;  4H2Y C;  2MVU A;  2XV6 A;  4BPH A;  1K8A Q;  1Q7Y Q;  1HQB A;  4BPG A;  2KG8 A;  1ACP A;  2PEQ A;  3GZL A;  3HZQ A;  4IPY A;  2XT1 A;  2P9X A;  1VQ8 P;  2PEK A;  2BUO A;  4IZ6 A;  2VLQ A;  3CXC O;  2KGC A;  1AF8 A;  3CCQ P;  2GDW A;  3CE7 A;  3CC7 P;  2CWO A;  1YIJ P;  1YJN P;  1KC8 Q;  4PWV B;  3CD6 P;  1AYI A;  3EJE A;  2K0Y A;  3G71 P;  4HKG A;  1IMQ A;  3EJD A;  1Q81 Q;  2Z45 A;  1VQ4 P;  3U43 A;  2PEM A;  2GYK A;  2Z46 A;  2FVF A;  1VQP P;  1YIT P;  2LOL A;  2FVE A;  2KOP A;  1GXH A;  3B4Q A;  2KOS A;  2MY5 A;  4XRQ A;  3GZM A;  2FVA A;  2PEN A;  4U0D A;  2MF4 A;  2K0D X;  1Q82 Q;  2M8N A;  5F2O A;  1L0I A;  2JB0 A;  2N6Y A;  1UJZ A;  2GZI A;  2Z44 A;  2ONT A;  2FQ2 A;  4U0C A;  4XFY A;  2EG5 A;  2KOD A;  1QRJ A;  5HVC A;  2E1M A;  1MZ8 A;  2VLO A;  3LMO A;  3RG6 C;  1VQ9 P;  3EJB A;  1AUM A;  4UHP B;  1EMV A;  2M5R A;  3GKL C;  3G26 A;  1FR2 A;  1NJI Q;  5F2N A;  5KP7 B;  4NEO A;  3G0V A;  3NY7 B;  4XFZ A;  3Q20 A;  3OW2 O;  2GZJ A;  1A43 A;  2JAZ A;  4H2W C;  1S72 P;  1CEI A;  3DS0 A;  2N5H A;  2K94 A;  4COC A;  3G1G A;  1K73 Q;  2LTE A;  5HGL A;  3CCV P;  3VRL C;  2KGE A;  4U0E A;  1K9M Q;  2PNG A;  3CCE P;  2KOQ A;  5F2K A;  3CCJ P;  2AF8 A;  1K30 A;  2GZE A;  2GDY A;  2JYG A;  4BPF A;  2FQ0 A;  4GR2 A;  2CG5 B;  2PEI A;  2MR7 A;  2KGD A;  5CZD B;  4PXH B;  1EOQ A;  2L9F A;  1ZMB A;  2XZ1 C;  2M8P A;  2FAD A;  1IMP A;  5KP8 B;  2ERH A;  5HGO A;  1N8R Q;  2JO0 A;  1EIA A;  2N6Z A;  2KWL A;  3G6E P;  3CCS P;  2KR5 A;  2OAR A;  3CCU P;  2BHV A;  1VQK P;  5EW5 E;  1VQ5 P;  1M1K Q;  1E0H A;  3GJN A;  3G29 A;  2L0Q A;  2DGY A;  2PEO A;  3G28 A;  4U0F A;  5BS1 A;  2K93 A;  1QVG O;  2L4B A;  4PH1 A;  1JJ2 O;  2JYL A;  3CCL P;  2LL8 A;  2CQ8 A;  2M8L A;  2VLN A;  1L0H A;  1E6J P;  1GPJ A;  2LF4 A;  2EIA A;  1D1D A;  2N98 A;  2JGP A;  4MRT C;  4DG9 A;  2KOO A;  3DS4 A;  2CGQ A;  3CPW O;  2KG6 A;  2FQ1 A;  2CNR A;  2LIU A;  1RO2 A;  3DS1 A;  4U0A A;  3DS2 A;  1DNY A;  1VQL P;  2QEX P;  4H2X C;  2N50 A;  2XZ0 D;  1BAJ A;  5HGM A;  2QA4 P;  2XXM A;  3CC4 P;  4F37 A;  2KOR A;  4WYM A;  3CCM P;  3CCR P;  2JU1 A;  4QNB A;  1OR5 A;  2X2B A;  1VQO P;  2WPT A;  1VQ7 P;  1VQ6 P;  3H0D A;  3HYB A;  4CA3 A;  2EFJ A;  4QKO A;  1VQM P;  4GR6 A;  3G4S P;  1KD1 Q;  1ZNV A;  3MGE A;  3RG2 A;  1BXI A;  1VKU A;  3CMA P;  1HY8 A;  3G21 A;  2PY8 A;  3DPH A;  1M74 A;  5BS2 A;  2ROQ A;  2AVA A;  1QVF O;  5I4T G;  1RNI A;  5DCK A;  2GDX A;  2K5X A;  2JBG A;  3DS5 A;  5HV8 A;  2AFD A;  1KQS O;  1DV5 A;  2QNW A;  1KLP A;  1X3O A;  4COP A;  2K92 A;  4XFX A;  1NQ4 A;  3G1I A;  2GZG A;  2OTL P;  2KGA A;  2MR8 A;  2KG9 A;  1IUQ A;  1M6E X;  5EJD A;  1Q86 Q;  3H4E A;  1F80 D;  2NO8 A;  1YHQ P;  2FAC A;  3E2D A;  3I56 P;  3P05 A;  2FAE A;  2K0X A;  1W2B O;  3M1M A;  2OTJ P;  2MD9 A;  3CC2 P;  2DNW A;  2LML A;  4PH0 A;  2VLP A;  7CEI A;  3DS3 A;  2PEJ A;  1VHN A;  3NTE A;  3I55 P;  4U0B A;  2LIW A;  1YJ9 P;  3B5I A;  2L6E A;  2FHS C;  3H47 A;  1M90 Q;  2EHS A;  2N5I A;  2JQ4 A;  2KW2 A;  4R0M A;  2JU2 A;  1YJW P;  3LRY A;  1T8K A;  1M6N A;  5KP6 B;  2L22 A;  2MVV A;  4M0I A;  3WBH A;  2AFE A;  5HGN A;  1RO0 A;  2VSQ A;  2GZF A;  3DTJ A;  2K2Q A; 
#chains in the Genus database with same CATH homology
 2GDX A;  1L0I A;  2N6Z A;  2N6Y A;  2KWL A;  5HV8 A;  2AFD A;  1DV5 A;  2LPK A;  2QNW A;  1KLP A;  1X3O A;  2EHT A;  2LKI A;  2FQ2 A;  2KR5 A;  2K92 A;  4H2Y C;  2MVU A;  5HVC A;  1NQ4 A;  4BPH A;  2L0Q A;  2KGA A;  3LMO A;  2MR8 A;  1HQB A;  2KG9 A;  4BPG A;  2KG8 A;  5EJD A;  1ACP A;  3EJB A;  3GZL A;  1F80 D;  2K93 A;  2M5R A;  2L4B A;  2FAC A;  2LL8 A;  2CQ8 A;  2FAE A;  1L0H A;  5KP7 B;  4NEO A;  3NY7 B;  4IZ6 A;  2K0X A;  2N98 A;  2JGP A;  4MRT C;  4DG9 A;  2KOO A;  2MD9 A;  2DNW A;  2LML A;  2CGQ A;  2KGC A;  1AF8 A;  4H2W C;  2KG6 A;  2FQ1 A;  2CNR A;  2LIU A;  1DNY A;  2GDW A;  3CE7 A;  2N5H A;  2K94 A;  4H2X C;  2N50 A;  2XZ0 D;  2LTE A;  2LIW A;  2KOR A;  2KGE A;  2FHS C;  4PWV B;  2JU1 A;  2PNG A;  1OR5 A;  2X2B A;  3EJE A;  2EHS A;  2K0Y A;  2N5I A;  2KOQ A;  2JQ4 A;  2KW2 A;  4HKG A;  2AF8 A;  3EJD A;  4CA3 A;  2GDY A;  2JU2 A;  4R0M A;  4BPF A;  2FQ0 A;  2CG5 B;  2MR7 A;  1T8K A;  5KP6 B;  2FVF A;  2KGD A;  5CZD B;  2L22 A;  4PXH B;  2LOL A;  2MVV A;  3RG2 A;  2L9F A;  2FVE A;  2KOP A;  1VKU A;  2XZ1 C;  2AFE A;  2FAD A;  2KOS A;  2MY5 A;  5KP8 B;  3GZM A;  2VSQ A;  1HY8 A;  2FVA A;  2MF4 A;  2ROQ A;  2AVA A;  2K2Q A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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