2CG5B

Structure of aminoadipate-semialdehyde dehydrogenase- phosphopantetheinyl transferase in complex with cytosolic acyl carrier protein and coenzyme a
Total Genus 19
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
19
sequence length
71
structure length
71
Chain Sequence
QRDLVEAVAHILGIRDLAAVNLDSSLADLGLDALMSVEVRQTLERELNLVLSVREVRQLTLRKLQELSSKA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Mechanism and Substrate Recognition of Human Holo Acp Synthase.
pubmed doi rcsb
source organism Homo sapiens
molecule tags Transferase/hydrolase
molecule keywords L-AMINOADIPATE-SEMIALDEHYDE DEHYDROGENASE-PHOSPHOPANTETHEINY
total genus 19
structure length 71
sequence length 71
ec nomenclature ec 1.1.1.100: 3-oxoacyl-[acyl-carrier-protein] reductase.
pdb deposition date 2006-02-27

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF00550 PP-binding Phosphopantetheine attachment site
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1200.10 Mainly Alpha Orthogonal Bundle Non-ribosomal Peptide Synthetase Peptidyl Carrier Protein; Chain A ACP-like 2cg5B00
2L22A 1DNYA 2N50A 4HKGA 2MVUA 2VSQA 2GDWA 2CNRA 2FVEA 4BPGA 2N98A 2L0QA 5HVCA 2KOPA 4H2YC 2CG5B 2L9FA 2K0XA 2LKIA 2X2BA 2KOSA 2KOQA 1OR5A 2EHTA 4MRTC 2ROQA 2KGAA 2AFDA 2XZ1C 2K0YA 3CE7A 2MD9A 2QNWA 2N5IA 2JGPA 1F80D 4BPFA 2EHSA 2MR7A 2K2QA 1HQBA 2MF4A 2KW2A 2JU2A 2FQ2A 2KG8A 2LMLA 4BPHA 4IZ6A 1X3OA 2K92A 2LPKA 2LIWA 2JQ4A 2K93A 3GZMA 2GDXA 4NEOA 2LTEA 2K94A 2M5RA 3NY7B 2KGEA 2CQ8A 2PNGA 4CA3A 2MY5A 4H2WC 4H2XC 5KP8B 5KP7B 3EJEA 5CZDB 2KWLA 1ACPA 1KLPA 3LMOA 2MR8A 2L4BA 2KGDA 2KORA 3EJBA 2FQ1A 1L0HA 2CGQA 2N6ZA 2KGCA 2AF8A 5HV8A 2FHSC 2FVFA 2FQ0A 2N6YA 1AF8A 2KG6A 5KP6B 1DV5A 1L0IA 2XZ0D 2DNWA 2FADA 3EJDA 2LL8A 5EJDA 1T8KA 1HY8A 2KOOA 3GZLA 4PXHB 2AFEA 2KR5A 2FACA 1VKUA 2KG9A 2N5HA 2AVAA 4DG9A 4PWVB 1NQ4A 2LIUA 2MVVA 2GDYA 4R0MA 3RG2A 2FAEA 2JU1A 2FVAA 2LOLA
chains in the Genus database with same CATH superfamily
2MVUA 1KC8Q 1EIAA 1A43A 1M6EX 2L0QA 3G21A 5HVCA 4H2YC 2CG5B 2KOSA 4MRTC 1D1DA 2K0DX 1F80D 1VQOP 2EHSA 4UHPB 3G4SP 3DS1A 1YJNP 2FQ2A 1KD1Q 1GPJA 2KG8A 2LMLA 2EFJA 1S72P 3DPHA 2EIAA 2K93A 4NEOA 2LTEA 2VLQA 1W2BO 3B5IA 2M8NA 1VQNP 4CA3A 4PH1A 1QVGO 2KODA 1K30A 3LMOA 7CEIA 4COCA 2KORA 2FQ1A 3G26A 2GZGA 2KGCA 4GR2A 2AF8A 2FHSC 1VQKP 1AF8A 2KG6A 3CC4P 5F2KA 5EJDA 2WPTA 2PY8A 3CPWO 2QEXP 4XFXA 2E1MA 5BS1A 2KG9A 4DG9A 4QKOA 4PWVB 2JAZA 2PEQA 2GZIA 2VLPA 3CCSP 1MZ8A 2LOLA 3G71P 2L22A 2VSQA 2GDWA 2N98A 3LRYA 3OW2O 2PEKA 1IUQA 4XFZA 2XT1A 2BUOA 2X2BA 1M6NA 2EHTA 2DGYA 2ROQA 4U0CA 2JBGA 2K0YA 3CE7A 2MD9A 2QNWA 5HGOA 2MR7A 2EG5A 1IMPA 2MF4A 2KW2A 2Z46A 1VQ6P 4U0AA 4XRQA 1RNIA 3HZQA 2OTLP 3G1IA 4XFYA 1VQ7P 2GDXA 2VLOA 3CCMP 3NY7B 3CC7P 2MY5A 4H2WC 4H2XC 5KP8B 2JB0A 1E6JP 3CMEP 5CZDB 1K8AQ 2PEJA 1KLPA 2MR8A 2CWOA 2KGDA 3DS4A 3EJBA 1L0HA 5DCKA 1M74A 2FQ0A 2N6YA 1QVFO 3E2DA 3I55P 2XZ0D 3EJDA 4U0DA 1HY8A 1VQ5P 2KOOA 2FACA 3NTEA 1ZMBA 1ZNVA 1Q7YQ 3G28A 1KQSO 2N5HA 3MGEA 2AVAA 1JJ2O 1RO2A 3CXCO 2QA4P 3H4EA 2FAEA 3M1MA 2NO8A 2PEIA 3DS2A 1DNYA 2N50A 4HKGA 5HGMA 3CCQP 3CCUP 1IMQA 1Q86Q 1GXHA 3VRLC 3CMAP 2KOPA 2L9FA 2K0XA 3RG6C 5BS2A 1EOQA 1VQ8P 2VLNA 2AFDA 1YITP 1EMVA 2XZ1C 3DS0A 4WYMA 3CCRP 1HQBA 2JU2A 3GJNA 4IZ6A 2K92A 2JQ4A 1GXGA 2L6EA 2M5RA 3CC2P 2XXMA 2PNGA 5KP7B 2M8PA 2ERHA 1VQ4P 1ACPA 1QRJA 2L4BA 3CCJP 1N8RQ 1RO0A 2JO0A 3DS3A 5EW5E 5KP6B 1CEIA 2PENA 1L0IA 4COPA 2DNWA 3WBHA 2LL8A 3I56P 3G6EP 4GR6A 2PEMA 1T8KA 2OARA 1VQLP 2AFEA 4U0BA 1UJZA 1VKUA 2GZFA 3P05A 2JYGA 3B4QA 2Z45A 4M0IA 3HYBA 2LIUA 2MVVA 2GDYA 1YJWP 2M8LA 5F2OA 3G29A 1A8OA 2JU1A 5I4TG 2ONTA 3CCEP 2FVAA 2OTJP 3GKLC 4IPYA 2CNRA 2FVEA 4BPGA 3H0DA 1M90Q 2K5XA 3G0VA 2GYKA 2LKIA 4XROA 5HGNA 2KOQA 1OR5A 1UNKA 2KGAA 1E0HA 1VHNA 2LF4A 2N5IA 2JGPA 1VQ9P 4BPFA 4U0EA 2K2QA 3DTJA 1YJ9P 2BHVA 4BPHA 1X3OA 3CD6P 2LPKA 4QNBA 2LIWA 4PH0A 3GZMA 2JYLA 1Q81Q 2K94A 2XV6A 2KGEA 2CQ8A 3CCVP 1AYIA 3DS5A 3EJEA 2KWLA 1Q82Q 2GZEA 3U43A 3CCLP 2CGQA 2N6ZA 5HV8A 2FVFA 2Z44A 1K9MQ 1DV5A 1BXIA 1YHQP 2FADA 5F2NA 1Z6MA 3GZLA 5JPAA 3H47A 1VQPP 4PXHB 2KR5A 1YIJP 2PEOA 1M1KQ 2P9XA 4U0FA 1K73Q 1NQ4A 1AUMA 5HGLA 1YI2P 1BAJA 4R0MA 3RG2A 3Q20A 1VQMP 2GZJA 1FR2A 1NJIQ 3G1GA 4F37A
chains in the Genus database with same CATH topology
2L22A 1DNYA 2N50A 4HKGA 2MVUA 2VSQA 2GDWA 2CNRA 2FVEA 4BPGA 2N98A 2L0QA 5HVCA 2KOPA 4H2YC 2CG5B 2L9FA 2K0XA 2LKIA 2X2BA 2KOSA 2KOQA 1OR5A 2EHTA 4MRTC 2ROQA 2KGAA 2AFDA 2XZ1C 2K0YA 3CE7A 2MD9A 2QNWA 2N5IA 2JGPA 1F80D 4BPFA 2EHSA 2MR7A 2K2QA 1HQBA 2MF4A 2KW2A 2JU2A 2FQ2A 2KG8A 2LMLA 4BPHA 4IZ6A 1X3OA 2K92A 2LPKA 2LIWA 2JQ4A 2K93A 3GZMA 2GDXA 4NEOA 2LTEA 2K94A 2M5RA 3NY7B 2KGEA 2CQ8A 2PNGA 4CA3A 2MY5A 4H2WC 4H2XC 5KP8B 5KP7B 3EJEA 5CZDB 2KWLA 1ACPA 1KLPA 3LMOA 2MR8A 2L4BA 2KGDA 2KORA 3EJBA 2FQ1A 1L0HA 2CGQA 2N6ZA 2KGCA 2AF8A 5HV8A 2FHSC 2FVFA 2FQ0A 2N6YA 1AF8A 2KG6A 5KP6B 1DV5A 1L0IA 2XZ0D 2DNWA 2FADA 3EJDA 2LL8A 5EJDA 1T8KA 1HY8A 2KOOA 3GZLA 4PXHB 2AFEA 2KR5A 2FACA 1VKUA 2KG9A 2N5HA 2AVAA 4DG9A 4PWVB 1NQ4A 2LIUA 2MVVA 2GDYA 4R0MA 3RG2A 2FAEA 2JU1A 2FVAA 2LOLA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2L22 A;  1DNY A;  2N50 A;  4HKG A;  2MVU A;  2VSQ A;  2GDW A;  2CNR A;  2FVE A;  4BPG A;  2N98 A;  2L0Q A;  5HVC A;  2KOP A;  4H2Y C;  2CG5 B;  2L9F A;  2K0X A;  2LKI A;  2X2B A;  2KOS A;  2KOQ A;  1OR5 A;  2EHT A;  4MRT C;  2ROQ A;  2KGA A;  2AFD A;  2XZ1 C;  2K0Y A;  3CE7 A;  2MD9 A;  2QNW A;  2N5I A;  2JGP A;  1F80 D;  4BPF A;  2EHS A;  2MR7 A;  2K2Q A;  1HQB A;  2MF4 A;  2KW2 A;  2JU2 A;  2FQ2 A;  2KG8 A;  2LML A;  4BPH A;  4IZ6 A;  1X3O A;  2K92 A;  2LPK A;  2LIW A;  2JQ4 A;  2K93 A;  3GZM A;  2GDX A;  4NEO A;  2LTE A;  2K94 A;  2M5R A;  3NY7 B;  2KGE A;  2CQ8 A;  2PNG A;  4CA3 A;  2MY5 A;  4H2W C;  4H2X C;  5KP8 B;  5KP7 B;  3EJE A;  5CZD B;  2KWL A;  1ACP A;  1KLP A;  3LMO A;  2MR8 A;  2L4B A;  2KGD A;  2KOR A;  3EJB A;  2FQ1 A;  1L0H A;  2CGQ A;  2N6Z A;  2KGC A;  2AF8 A;  5HV8 A;  2FHS C;  2FVF A;  2FQ0 A;  2N6Y A;  1AF8 A;  2KG6 A;  5KP6 B;  1DV5 A;  1L0I A;  2XZ0 D;  2DNW A;  2FAD A;  3EJD A;  2LL8 A;  5EJD A;  1T8K A;  1HY8 A;  2KOO A;  3GZL A;  4PXH B;  2AFE A;  2KR5 A;  2FAC A;  1VKU A;  2KG9 A;  2N5H A;  2AVA A;  4DG9 A;  4PWV B;  1NQ4 A;  2LIU A;  2MVV A;  2GDY A;  4R0M A;  3RG2 A;  2FAE A;  2JU1 A;  2FVA A;  2LOL A; 
#chains in the Genus database with same CATH topology
 2MVU A;  1KC8 Q;  1EIA A;  1A43 A;  1M6E X;  2L0Q A;  3G21 A;  5HVC A;  4H2Y C;  2CG5 B;  2KOS A;  4MRT C;  1D1D A;  2K0D X;  1F80 D;  1VQO P;  2EHS A;  4UHP B;  3G4S P;  3DS1 A;  1YJN P;  2FQ2 A;  1KD1 Q;  1GPJ A;  2KG8 A;  2LML A;  2EFJ A;  1S72 P;  3DPH A;  2EIA A;  2K93 A;  4NEO A;  2LTE A;  2VLQ A;  1W2B O;  3B5I A;  2M8N A;  1VQN P;  4CA3 A;  4PH1 A;  1QVG O;  2KOD A;  1K30 A;  3LMO A;  7CEI A;  4COC A;  2KOR A;  2FQ1 A;  3G26 A;  2GZG A;  2KGC A;  4GR2 A;  2AF8 A;  2FHS C;  1VQK P;  1AF8 A;  2KG6 A;  3CC4 P;  5F2K A;  5EJD A;  2WPT A;  2PY8 A;  3CPW O;  2QEX P;  4XFX A;  2E1M A;  5BS1 A;  2KG9 A;  4DG9 A;  4QKO A;  4PWV B;  2JAZ A;  2PEQ A;  2GZI A;  2VLP A;  3CCS P;  1MZ8 A;  2LOL A;  3G71 P;  2L22 A;  2VSQ A;  2GDW A;  2N98 A;  3LRY A;  3OW2 O;  2PEK A;  1IUQ A;  4XFZ A;  2XT1 A;  2BUO A;  2X2B A;  1M6N A;  2EHT A;  2DGY A;  2ROQ A;  4U0C A;  2JBG A;  2K0Y A;  3CE7 A;  2MD9 A;  2QNW A;  5HGO A;  2MR7 A;  2EG5 A;  1IMP A;  2MF4 A;  2KW2 A;  2Z46 A;  1VQ6 P;  4U0A A;  4XRQ A;  1RNI A;  3HZQ A;  2OTL P;  3G1I A;  4XFY A;  1VQ7 P;  2GDX A;  2VLO A;  3CCM P;  3NY7 B;  3CC7 P;  2MY5 A;  4H2W C;  4H2X C;  5KP8 B;  2JB0 A;  1E6J P;  3CME P;  5CZD B;  1K8A Q;  2PEJ A;  1KLP A;  2MR8 A;  2CWO A;  2KGD A;  3DS4 A;  3EJB A;  1L0H A;  5DCK A;  1M74 A;  2FQ0 A;  2N6Y A;  1QVF O;  3E2D A;  3I55 P;  2XZ0 D;  3EJD A;  4U0D A;  1HY8 A;  1VQ5 P;  2KOO A;  2FAC A;  3NTE A;  1ZMB A;  1ZNV A;  1Q7Y Q;  3G28 A;  1KQS O;  2N5H A;  3MGE A;  2AVA A;  1JJ2 O;  1RO2 A;  3CXC O;  2QA4 P;  3H4E A;  2FAE A;  3M1M A;  2NO8 A;  2PEI A;  3DS2 A;  1DNY A;  2N50 A;  4HKG A;  5HGM A;  3CCQ P;  3CCU P;  1IMQ A;  1Q86 Q;  1GXH A;  3VRL C;  3CMA P;  2KOP A;  2L9F A;  2K0X A;  3RG6 C;  5BS2 A;  1EOQ A;  1VQ8 P;  2VLN A;  2AFD A;  1YIT P;  1EMV A;  2XZ1 C;  3DS0 A;  4WYM A;  3CCR P;  1HQB A;  2JU2 A;  3GJN A;  4IZ6 A;  2K92 A;  2JQ4 A;  1GXG A;  2L6E A;  2M5R A;  3CC2 P;  2XXM A;  2PNG A;  5KP7 B;  2M8P A;  2ERH A;  1VQ4 P;  1ACP A;  1QRJ A;  2L4B A;  3CCJ P;  1N8R Q;  1RO0 A;  2JO0 A;  3DS3 A;  5EW5 E;  5KP6 B;  1CEI A;  2PEN A;  1L0I A;  4COP A;  2DNW A;  3WBH A;  2LL8 A;  3I56 P;  3G6E P;  4GR6 A;  2PEM A;  1T8K A;  2OAR A;  1VQL P;  2AFE A;  4U0B A;  1UJZ A;  1VKU A;  2GZF A;  3P05 A;  2JYG A;  3B4Q A;  2Z45 A;  4M0I A;  3HYB A;  2LIU A;  2MVV A;  2GDY A;  1YJW P;  2M8L A;  5F2O A;  3G29 A;  1A8O A;  2JU1 A;  5I4T G;  2ONT A;  3CCE P;  2FVA A;  2OTJ P;  3GKL C;  4IPY A;  2CNR A;  2FVE A;  4BPG A;  3H0D A;  1M90 Q;  2K5X A;  3G0V A;  2GYK A;  2LKI A;  4XRO A;  5HGN A;  2KOQ A;  1OR5 A;  1UNK A;  2KGA A;  1E0H A;  1VHN A;  2LF4 A;  2N5I A;  2JGP A;  1VQ9 P;  4BPF A;  4U0E A;  2K2Q A;  3DTJ A;  1YJ9 P;  2BHV A;  4BPH A;  1X3O A;  3CD6 P;  2LPK A;  4QNB A;  2LIW A;  4PH0 A;  3GZM A;  2JYL A;  1Q81 Q;  2K94 A;  2XV6 A;  2KGE A;  2CQ8 A;  3CCV P;  1AYI A;  3DS5 A;  3EJE A;  2KWL A;  1Q82 Q;  2GZE A;  3U43 A;  3CCL P;  2CGQ A;  2N6Z A;  5HV8 A;  2FVF A;  2Z44 A;  1K9M Q;  1DV5 A;  1BXI A;  1YHQ P;  2FAD A;  5F2N A;  1Z6M A;  3GZL A;  5JPA A;  3H47 A;  1VQP P;  4PXH B;  2KR5 A;  1YIJ P;  2PEO A;  1M1K Q;  2P9X A;  4U0F A;  1K73 Q;  1NQ4 A;  1AUM A;  5HGL A;  1YI2 P;  1BAJ A;  4R0M A;  3RG2 A;  3Q20 A;  1VQM P;  2GZJ A;  1FR2 A;  1NJI Q;  3G1G A;  4F37 A; 
#chains in the Genus database with same CATH homology
 2L22 A;  1DNY A;  2N50 A;  4HKG A;  2MVU A;  2VSQ A;  2GDW A;  2CNR A;  2FVE A;  4BPG A;  2N98 A;  2L0Q A;  5HVC A;  2KOP A;  4H2Y C;  2CG5 B;  2L9F A;  2K0X A;  2LKI A;  2X2B A;  2KOS A;  2KOQ A;  1OR5 A;  2EHT A;  4MRT C;  2ROQ A;  2KGA A;  2AFD A;  2XZ1 C;  2K0Y A;  3CE7 A;  2MD9 A;  2QNW A;  2N5I A;  2JGP A;  1F80 D;  4BPF A;  2EHS A;  2MR7 A;  2K2Q A;  1HQB A;  2MF4 A;  2KW2 A;  2JU2 A;  2FQ2 A;  2KG8 A;  2LML A;  4BPH A;  4IZ6 A;  1X3O A;  2K92 A;  2LPK A;  2LIW A;  2JQ4 A;  2K93 A;  3GZM A;  2GDX A;  4NEO A;  2LTE A;  2K94 A;  2M5R A;  3NY7 B;  2KGE A;  2CQ8 A;  2PNG A;  4CA3 A;  2MY5 A;  4H2W C;  4H2X C;  5KP8 B;  5KP7 B;  3EJE A;  5CZD B;  2KWL A;  1ACP A;  1KLP A;  3LMO A;  2MR8 A;  2L4B A;  2KGD A;  2KOR A;  3EJB A;  2FQ1 A;  1L0H A;  2CGQ A;  2N6Z A;  2KGC A;  2AF8 A;  5HV8 A;  2FHS C;  2FVF A;  2FQ0 A;  2N6Y A;  1AF8 A;  2KG6 A;  5KP6 B;  1DV5 A;  1L0I A;  2XZ0 D;  2DNW A;  2FAD A;  3EJD A;  2LL8 A;  5EJD A;  1T8K A;  1HY8 A;  2KOO A;  3GZL A;  4PXH B;  2AFE A;  2KR5 A;  2FAC A;  1VKU A;  2KG9 A;  2N5H A;  2AVA A;  4DG9 A;  4PWV B;  1NQ4 A;  2LIU A;  2MVV A;  2GDY A;  4R0M A;  3RG2 A;  2FAE A;  2JU1 A;  2FVA A;  2LOL A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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