2CG5B

Structure of aminoadipate-semialdehyde dehydrogenase- phosphopantetheinyl transferase in complex with cytosolic acyl carrier protein and coenzyme a
Total Genus 19
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
19
sequence length
71
structure length
71
Chain Sequence
QRDLVEAVAHILGIRDLAAVNLDSSLADLGLDALMSVEVRQTLERELNLVLSVREVRQLTLRKLQELSSKA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule keywords L-AMINOADIPATE-SEMIALDEHYDE DEHYDROGENASE-PHOSPHOPANTETHEINY
publication title Mechanism and Substrate Recognition of Human Holo Acp Synthase.
pubmed doi rcsb
source organism Homo sapiens
molecule tags Transferase/hydrolase
total genus 19
structure length 71
sequence length 71
ec nomenclature ec 1.1.1.100: 3-oxoacyl-[acyl-carrier-protein] reductase.
pdb deposition date 2006-02-27

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF00550 PP-binding Phosphopantetheine attachment site
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1200.10 Mainly Alpha Orthogonal Bundle Non-ribosomal Peptide Synthetase Peptidyl Carrier Protein; Chain A ACP-like 2cg5B00
2QNWA 2L9FA 5HV8A 1HY8A 3EJBA 1L0IA 4HKGA 4PXHB 4BPGA 2FHSC 1T8KA 2GDWA 2L22A 2LL8A 1NQ4A 2GDYA 2LKIA 2LIWA 2MF4A 2JQ4A 2X2BA 3EJDA 1KLPA 2EHTA 3RG2A 2KORA 2EHSA 2K0XA 2KR5A 2ROQA 2LOLA 2N98A 2FAEA 3GZLA 2K92A 5EJDA 2KG8A 1HQBA 2FVAA 2K0YA 1VKUA 4BPHA 2MVUA 2FVEA 4H2WC 2MD9A 3CE7A 2FQ2A 2N6ZA 2VSQA 2N5HA 2CNRA 2KGAA 4H2YC 2AFEA 4PWVB 4DG9A 2FQ0A 2KGCA 4IZ6A 1OR5A 2KW2A 2AFDA 2MVVA 2PNGA 2FVFA 2MY5A 2KG6A 4NEOA 2N5IA 2LIUA 1L0HA 2KOPA 2AF8A 2M5RA 2FADA 2K94A 4H2XC 5KP6B 5KP7B 2DNWA 2LPKA 2KGEA 2CQ8A 2L0QA 2K93A 1X3OA 2K2QA 4BPFA 2KGDA 2FQ1A 2JU2A 5CZDB 2FACA 2L4BA 2N50A 2JGPA 5KP8B 2JU1A 2KOSA 2KWLA 2XZ0D 2MR8A 4R0MA 2LTEA 2LMLA 2CG5B 4MRTC 2KG9A 2GDXA 2AVAA 5HVCA 2CGQA 3LMOA 2MR7A 1F80D 1ACPA 3NY7B 1DV5A 2KOOA 1AF8A 3EJEA 2KOQA 1DNYA 2N6YA 2XZ1C 4CA3A 3GZMA
chains in the Genus database with same CATH superfamily
4U0BA 2XXMA 2L9FA 2PENA 5JPAA 3EJBA 1VQLP 2PEOA 4GR6A 2JB0A 3CCLP 1ZMBA 4COPA 3CMAP 5I4TG 1VQNP 1VQ8P 2N98A 2P9XA 2MVUA 1JJ2O 4H2WC 2M8PA 2FQ2A 3G71P 3GJNA 5DCKA 2E1MA 3DS0A 4H2YC 3CCSP 1D1DA 3P05A 1YJNP 2DGYA 1E6JP 3CPWO 3G26A 1W2BO 4H2XC 5KP7B 2PEQA 3G21A 3CD6P 2CQ8A 2L0QA 5F2KA 2XT1A 3H0DA 2QA4P 3DS5A 3G28A 2L6EA 3CCQP 4UHPB 2FACA 2ERHA 1RO0A 5KP8B 4WYMA 1VQOP 4R0MA 2LTEA 1EOQA 1FR2A 3HYBA 5HVCA 4F37A 3B5IA 1F80D 3NY7B 2KOOA 1K30A 3WBHA 3DS4A 2OTLP 1DNYA 3Q20A 2GZGA 1YITP 2XZ1C 3GZMA 2QNWA 1HY8A 4U0CA 2Z46A 4PXHB 1VQKP 2JBGA 1M6NA 2GDWA 2L22A 2LL8A 4QKOA 1AYIA 3CC7P 2LKIA 3CCEP 3EJDA 3RG2A 2EHSA 2K0XA 2KR5A 1K8AQ 3G6EP 3G29A 4GR2A 3GZLA 2FVAA 4BPHA 1VQMP 1ZNVA 2MD9A 2N6ZA 1KQSO 3B4QA 3CCMP 2VLOA 2BHVA 3GKLC 2KODA 1M6EX 2NO8A 3CCRP 2AFDA 2FVFA 1YHQP 2KG6A 3I55P 4PH0A 2QEXP 3DS1A 2LF4A 2K0DX 2AF8A 2M5RA 5KP6B 3G4SP 1E0HA 2DNWA 2VLQA 1UJZA 2KGEA 1M74A 3CCVP 5EW5E 2JU2A 1KD1Q 1YJWP 2Z45A 2JU1A 2KWLA 2M8NA 3LRYA 2MR8A 5HGLA 1BXIA 2EFJA 2CG5B 2GDXA 2AVAA 3M1MA 2CGQA 2MR7A 3CC4P 2EG5A 2WPTA 3NTEA 1EMVA 2GZIA 2PEKA 2ONTA 2KOQA 1N8RQ 2N6YA 2PEIA 3CC2P 1A8OA 2VLPA 2Z44A 1EIAA 2GZFA 4HKGA 4BPGA 2FHSC 1NQ4A 1BAJA 2GDYA 1GPJA 1K9MQ 2MF4A 4XROA 1VQPP 2JQ4A 2PY8A 2GZJA 2PEJA 2X2BA 1KLPA 1MZ8A 2ROQA 2JYLA 2LOLA 2KG8A 3CMEP 1VKUA 1Q82Q 4XFZA 4IPYA 4XFYA 4COCA 4U0EA 1YIJP 2CNRA 2KGAA 2AFEA 4DG9A 2FQ0A 1VQ6P 4U0AA 1Z6MA 1OR5A 1UNKA 1GXGA 2XV6A 2PNGA 2MY5A 3CCJP 2LIUA 3DTJA 5F2OA 5BS2A 1A43A 2KOPA 3G1IA 2OARA 1VQ7P 3H4EA 2FQ1A 2OTJP 2EIAA 3DS2A 2KOSA 2XZ0D 2BUOA 3U43A 7CEIA 4PH1A 3H47A 2KG9A 1VQ4P 4XRQA 1QRJA 3I56P 3CCUP 1AF8A 3EJEA 1VHNA 4CA3A 5HV8A 1M90Q 1VQ9P 1L0IA 1T8KA 1QVGO 2JAZA 2GZEA 2JYGA 1QVFO 1NJIQ 2LIWA 1IUQA 3CXCO 2EHTA 2KORA 2FAEA 2K92A 5EJDA 1IMPA 1HQBA 2K0YA 1KC8Q 2FVEA 3CE7A 3VRLC 2VSQA 1RO2A 3OW2O 2N5HA 1IMQA 1YJ9P 3MGEA 4PWVB 5HGMA 2CWOA 1GXHA 2KGCA 4IZ6A 1Q86Q 3G0VA 4U0DA 2KW2A 3DS3A 2MVVA 3G1GA 3RG6C 4NEOA 2N5IA 1L0HA 5F2NA 1RNIA 1CEIA 4XFXA 1Q7YQ 2FADA 2K94A 3DPHA 1VQ5P 2LPKA 1K73Q 4QNBA 2K93A 1X3OA 2K2QA 4BPFA 2KGDA 5HGNA 2VLNA 5CZDB 2L4BA 2N50A 2JGPA 1YI2P 1M1KQ 2M8LA 1Q81Q 2LMLA 2PEMA 4MRTC 2GYKA 3HZQA 5BS1A 4M0IA 1AUMA 3LMOA 1ACPA 1DV5A 2K5XA 5HGOA 4U0FA 2JO0A 3E2DA 1S72P
chains in the Genus database with same CATH topology
2QNWA 2L9FA 5HV8A 1HY8A 3EJBA 1L0IA 4HKGA 4PXHB 4BPGA 2FHSC 1T8KA 2GDWA 2L22A 2LL8A 1NQ4A 2GDYA 2LKIA 2LIWA 2MF4A 2JQ4A 2X2BA 3EJDA 1KLPA 2EHTA 3RG2A 2KORA 2EHSA 2K0XA 2KR5A 2ROQA 2LOLA 2N98A 2FAEA 3GZLA 2K92A 5EJDA 2KG8A 1HQBA 2FVAA 2K0YA 1VKUA 4BPHA 2MVUA 2FVEA 4H2WC 2MD9A 3CE7A 2FQ2A 2N6ZA 2VSQA 2N5HA 2CNRA 2KGAA 4H2YC 2AFEA 4PWVB 4DG9A 2FQ0A 2KGCA 4IZ6A 1OR5A 2KW2A 2AFDA 2MVVA 2PNGA 2FVFA 2MY5A 2KG6A 4NEOA 2N5IA 2LIUA 1L0HA 2KOPA 2AF8A 2M5RA 2FADA 2K94A 4H2XC 5KP6B 5KP7B 2DNWA 2LPKA 2KGEA 2CQ8A 2L0QA 2K93A 1X3OA 2K2QA 4BPFA 2KGDA 2FQ1A 2JU2A 5CZDB 2FACA 2L4BA 2N50A 2JGPA 5KP8B 2JU1A 2KOSA 2KWLA 2XZ0D 2MR8A 4R0MA 2LTEA 2LMLA 2CG5B 4MRTC 2KG9A 2GDXA 2AVAA 5HVCA 2CGQA 3LMOA 2MR7A 1F80D 1ACPA 3NY7B 1DV5A 2KOOA 1AF8A 3EJEA 2KOQA 1DNYA 2N6YA 2XZ1C 4CA3A 3GZMA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2QNW A;  2L9F A;  5HV8 A;  1HY8 A;  3EJB A;  1L0I A;  4HKG A;  4PXH B;  4BPG A;  2FHS C;  1T8K A;  2GDW A;  2L22 A;  2LL8 A;  1NQ4 A;  2GDY A;  2LKI A;  2LIW A;  2MF4 A;  2JQ4 A;  2X2B A;  3EJD A;  1KLP A;  2EHT A;  3RG2 A;  2KOR A;  2EHS A;  2K0X A;  2KR5 A;  2ROQ A;  2LOL A;  2N98 A;  2FAE A;  3GZL A;  2K92 A;  5EJD A;  2KG8 A;  1HQB A;  2FVA A;  2K0Y A;  1VKU A;  4BPH A;  2MVU A;  2FVE A;  4H2W C;  2MD9 A;  3CE7 A;  2FQ2 A;  2N6Z A;  2VSQ A;  2N5H A;  2CNR A;  2KGA A;  4H2Y C;  2AFE A;  4PWV B;  4DG9 A;  2FQ0 A;  2KGC A;  4IZ6 A;  1OR5 A;  2KW2 A;  2AFD A;  2MVV A;  2PNG A;  2FVF A;  2MY5 A;  2KG6 A;  4NEO A;  2N5I A;  2LIU A;  1L0H A;  2KOP A;  2AF8 A;  2M5R A;  2FAD A;  2K94 A;  4H2X C;  5KP6 B;  5KP7 B;  2DNW A;  2LPK A;  2KGE A;  2CQ8 A;  2L0Q A;  2K93 A;  1X3O A;  2K2Q A;  4BPF A;  2KGD A;  2FQ1 A;  2JU2 A;  5CZD B;  2FAC A;  2L4B A;  2N50 A;  2JGP A;  5KP8 B;  2JU1 A;  2KOS A;  2KWL A;  2XZ0 D;  2MR8 A;  4R0M A;  2LTE A;  2LML A;  2CG5 B;  4MRT C;  2KG9 A;  2GDX A;  2AVA A;  5HVC A;  2CGQ A;  3LMO A;  2MR7 A;  1F80 D;  1ACP A;  3NY7 B;  1DV5 A;  2KOO A;  1AF8 A;  3EJE A;  2KOQ A;  1DNY A;  2N6Y A;  2XZ1 C;  4CA3 A;  3GZM A; 
#chains in the Genus database with same CATH topology
 4U0B A;  2XXM A;  2L9F A;  2PEN A;  5JPA A;  3EJB A;  1VQL P;  2PEO A;  4GR6 A;  2JB0 A;  3CCL P;  1ZMB A;  4COP A;  3CMA P;  5I4T G;  1VQN P;  1VQ8 P;  2N98 A;  2P9X A;  2MVU A;  1JJ2 O;  4H2W C;  2M8P A;  2FQ2 A;  3G71 P;  3GJN A;  5DCK A;  2E1M A;  3DS0 A;  4H2Y C;  3CCS P;  1D1D A;  3P05 A;  1YJN P;  2DGY A;  1E6J P;  3CPW O;  3G26 A;  1W2B O;  4H2X C;  5KP7 B;  2PEQ A;  3G21 A;  3CD6 P;  2CQ8 A;  2L0Q A;  5F2K A;  2XT1 A;  3H0D A;  2QA4 P;  3DS5 A;  3G28 A;  2L6E A;  3CCQ P;  4UHP B;  2FAC A;  2ERH A;  1RO0 A;  5KP8 B;  4WYM A;  1VQO P;  4R0M A;  2LTE A;  1EOQ A;  1FR2 A;  3HYB A;  5HVC A;  4F37 A;  3B5I A;  1F80 D;  3NY7 B;  2KOO A;  1K30 A;  3WBH A;  3DS4 A;  2OTL P;  1DNY A;  3Q20 A;  2GZG A;  1YIT P;  2XZ1 C;  3GZM A;  2QNW A;  1HY8 A;  4U0C A;  2Z46 A;  4PXH B;  1VQK P;  2JBG A;  1M6N A;  2GDW A;  2L22 A;  2LL8 A;  4QKO A;  1AYI A;  3CC7 P;  2LKI A;  3CCE P;  3EJD A;  3RG2 A;  2EHS A;  2K0X A;  2KR5 A;  1K8A Q;  3G6E P;  3G29 A;  4GR2 A;  3GZL A;  2FVA A;  4BPH A;  1VQM P;  1ZNV A;  2MD9 A;  2N6Z A;  1KQS O;  3B4Q A;  3CCM P;  2VLO A;  2BHV A;  3GKL C;  2KOD A;  1M6E X;  2NO8 A;  3CCR P;  2AFD A;  2FVF A;  1YHQ P;  2KG6 A;  3I55 P;  4PH0 A;  2QEX P;  3DS1 A;  2LF4 A;  2K0D X;  2AF8 A;  2M5R A;  5KP6 B;  3G4S P;  1E0H A;  2DNW A;  2VLQ A;  1UJZ A;  2KGE A;  1M74 A;  3CCV P;  5EW5 E;  2JU2 A;  1KD1 Q;  1YJW P;  2Z45 A;  2JU1 A;  2KWL A;  2M8N A;  3LRY A;  2MR8 A;  5HGL A;  1BXI A;  2EFJ A;  2CG5 B;  2GDX A;  2AVA A;  3M1M A;  2CGQ A;  2MR7 A;  3CC4 P;  2EG5 A;  2WPT A;  3NTE A;  1EMV A;  2GZI A;  2PEK A;  2ONT A;  2KOQ A;  1N8R Q;  2N6Y A;  2PEI A;  3CC2 P;  1A8O A;  2VLP A;  2Z44 A;  1EIA A;  2GZF A;  4HKG A;  4BPG A;  2FHS C;  1NQ4 A;  1BAJ A;  2GDY A;  1GPJ A;  1K9M Q;  2MF4 A;  4XRO A;  1VQP P;  2JQ4 A;  2PY8 A;  2GZJ A;  2PEJ A;  2X2B A;  1KLP A;  1MZ8 A;  2ROQ A;  2JYL A;  2LOL A;  2KG8 A;  3CME P;  1VKU A;  1Q82 Q;  4XFZ A;  4IPY A;  4XFY A;  4COC A;  4U0E A;  1YIJ P;  2CNR A;  2KGA A;  2AFE A;  4DG9 A;  2FQ0 A;  1VQ6 P;  4U0A A;  1Z6M A;  1OR5 A;  1UNK A;  1GXG A;  2XV6 A;  2PNG A;  2MY5 A;  3CCJ P;  2LIU A;  3DTJ A;  5F2O A;  5BS2 A;  1A43 A;  2KOP A;  3G1I A;  2OAR A;  1VQ7 P;  3H4E A;  2FQ1 A;  2OTJ P;  2EIA A;  3DS2 A;  2KOS A;  2XZ0 D;  2BUO A;  3U43 A;  7CEI A;  4PH1 A;  3H47 A;  2KG9 A;  1VQ4 P;  4XRQ A;  1QRJ A;  3I56 P;  3CCU P;  1AF8 A;  3EJE A;  1VHN A;  4CA3 A;  5HV8 A;  1M90 Q;  1VQ9 P;  1L0I A;  1T8K A;  1QVG O;  2JAZ A;  2GZE A;  2JYG A;  1QVF O;  1NJI Q;  2LIW A;  1IUQ A;  3CXC O;  2EHT A;  2KOR A;  2FAE A;  2K92 A;  5EJD A;  1IMP A;  1HQB A;  2K0Y A;  1KC8 Q;  2FVE A;  3CE7 A;  3VRL C;  2VSQ A;  1RO2 A;  3OW2 O;  2N5H A;  1IMQ A;  1YJ9 P;  3MGE A;  4PWV B;  5HGM A;  2CWO A;  1GXH A;  2KGC A;  4IZ6 A;  1Q86 Q;  3G0V A;  4U0D A;  2KW2 A;  3DS3 A;  2MVV A;  3G1G A;  3RG6 C;  4NEO A;  2N5I A;  1L0H A;  5F2N A;  1RNI A;  1CEI A;  4XFX A;  1Q7Y Q;  2FAD A;  2K94 A;  3DPH A;  1VQ5 P;  2LPK A;  1K73 Q;  4QNB A;  2K93 A;  1X3O A;  2K2Q A;  4BPF A;  2KGD A;  5HGN A;  2VLN A;  5CZD B;  2L4B A;  2N50 A;  2JGP A;  1YI2 P;  1M1K Q;  2M8L A;  1Q81 Q;  2LML A;  2PEM A;  4MRT C;  2GYK A;  3HZQ A;  5BS1 A;  4M0I A;  1AUM A;  3LMO A;  1ACP A;  1DV5 A;  2K5X A;  5HGO A;  4U0F A;  2JO0 A;  3E2D A;  1S72 P; 
#chains in the Genus database with same CATH homology
 2QNW A;  2L9F A;  5HV8 A;  1HY8 A;  3EJB A;  1L0I A;  4HKG A;  4PXH B;  4BPG A;  2FHS C;  1T8K A;  2GDW A;  2L22 A;  2LL8 A;  1NQ4 A;  2GDY A;  2LKI A;  2LIW A;  2MF4 A;  2JQ4 A;  2X2B A;  3EJD A;  1KLP A;  2EHT A;  3RG2 A;  2KOR A;  2EHS A;  2K0X A;  2KR5 A;  2ROQ A;  2LOL A;  2N98 A;  2FAE A;  3GZL A;  2K92 A;  5EJD A;  2KG8 A;  1HQB A;  2FVA A;  2K0Y A;  1VKU A;  4BPH A;  2MVU A;  2FVE A;  4H2W C;  2MD9 A;  3CE7 A;  2FQ2 A;  2N6Z A;  2VSQ A;  2N5H A;  2CNR A;  2KGA A;  4H2Y C;  2AFE A;  4PWV B;  4DG9 A;  2FQ0 A;  2KGC A;  4IZ6 A;  1OR5 A;  2KW2 A;  2AFD A;  2MVV A;  2PNG A;  2FVF A;  2MY5 A;  2KG6 A;  4NEO A;  2N5I A;  2LIU A;  1L0H A;  2KOP A;  2AF8 A;  2M5R A;  2FAD A;  2K94 A;  4H2X C;  5KP6 B;  5KP7 B;  2DNW A;  2LPK A;  2KGE A;  2CQ8 A;  2L0Q A;  2K93 A;  1X3O A;  2K2Q A;  4BPF A;  2KGD A;  2FQ1 A;  2JU2 A;  5CZD B;  2FAC A;  2L4B A;  2N50 A;  2JGP A;  5KP8 B;  2JU1 A;  2KOS A;  2KWL A;  2XZ0 D;  2MR8 A;  4R0M A;  2LTE A;  2LML A;  2CG5 B;  4MRT C;  2KG9 A;  2GDX A;  2AVA A;  5HVC A;  2CGQ A;  3LMO A;  2MR7 A;  1F80 D;  1ACP A;  3NY7 B;  1DV5 A;  2KOO A;  1AF8 A;  3EJE A;  2KOQ A;  1DNY A;  2N6Y A;  2XZ1 C;  4CA3 A;  3GZM A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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