2CG5B

Structure of aminoadipate-semialdehyde dehydrogenase- phosphopantetheinyl transferase in complex with cytosolic acyl carrier protein and coenzyme a
Total Genus 19
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
19
sequence length
71
structure length
71
Chain Sequence
QRDLVEAVAHILGIRDLAAVNLDSSLADLGLDALMSVEVRQTLERELNLVLSVREVRQLTLRKLQELSSKA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Mechanism and Substrate Recognition of Human Holo Acp Synthase.
pubmed doi rcsb
source organism Homo sapiens
molecule tags Transferase/hydrolase
molecule keywords L-AMINOADIPATE-SEMIALDEHYDE DEHYDROGENASE-PHOSPHOPANTETHEINY
total genus 19
structure length 71
sequence length 71
ec nomenclature ec 1.1.1.100: 3-oxoacyl-[acyl-carrier-protein] reductase.
pdb deposition date 2006-02-27

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF00550 PP-binding Phosphopantetheine attachment site
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1200.10 Mainly Alpha Orthogonal Bundle Non-ribosomal Peptide Synthetase Peptidyl Carrier Protein; Chain A ACP-like 2cg5B00
2CG5B 2DNWA 2FQ2A 2N50A 2K0XA 1HQBA 1T8KA 5CZDB 2MR8A 4H2XC 5HV8A 2N98A 2JU1A 4NEOA 4DG9A 3RG2A 2LIUA 2FAEA 2KGAA 2KG8A 2EHTA 2PNGA 2N6YA 2L9FA 2L4BA 2K92A 2LTEA 4PWVB 2K2QA 2FVEA 2MVUA 2FADA 3LMOA 2LIWA 4IZ6A 2KORA 2FQ1A 2FACA 1NQ4A 2CGQA 2JU2A 2KR5A 4MRTC 4R0MA 4BPFA 3EJDA 2MY5A 4BPGA 2LL8A 3GZMA 2X2BA 2LOLA 2L22A 2GDYA 2QNWA 3GZLA 2JGPA 2MF4A 2KWLA 4H2WC 2LPKA 3CE7A 2AFEA 1OR5A 2AVAA 2L0QA 2ROQA 2KGEA 2KOOA 2FQ0A 2AFDA 2KG6A 2M5RA 2XZ1C 3NY7B 4HKGA 2LMLA 1X3OA 2CQ8A 2VSQA 2MD9A 1DV5A 2FVAA 2JQ4A 1DNYA 2GDXA 2FVFA 3EJBA 2KW2A 2CNRA 2KGCA 2N6ZA 2K93A 4H2YC 1ACPA 1L0IA 4PXHB 4BPHA 2KGDA 1VKUA 2LKIA 5KP6B 2AF8A 1F80D 5KP8B 1L0HA 3EJEA 1HY8A 2KOPA 2K94A 2N5HA 2FHSC 4CA3A 2K0YA 1AF8A 2KG9A 1KLPA 5HVCA 2KOQA 2EHSA 5EJDA 2MVVA 2KOSA 5KP7B 2GDWA 2N5IA 2XZ0D 2MR7A
chains in the Genus database with same CATH superfamily
1IMQA 2CG5B 5JPAA 2OARA 1W2BO 1T8KA 2MR8A 3CCQP 4XFZA 4XFYA 3H47A 2GZFA 2XXMA 3RG2A 3CCSP 3G71P 2KGAA 2GZGA 4PH0A 2ONTA 1UJZA 4PWVB 2MVUA 1VQOP 1K30A 4M0IA 2KORA 2K5XA 5BS2A 2PEOA 4BPFA 1BXIA 4BPGA 3G21A 3HZQA 2QNWA 3DS0A 1A8OA 2QA4P 1VQ6P 3GKLC 2JAZA 4GR2A 2EIAA 1K73Q 2ROQA 2KGEA 2XZ1C 5BS1A 1VQ7P 1X3OA 2VSQA 1EIAA 2JQ4A 1DNYA 2GDXA 1IMPA 2CNRA 1A43A 3P05A 3E2DA 1KD1Q 1L0IA 2Z45A 4PXHB 2JB0A 4BPHA 3G28A 2KGDA 1D1DA 1M90Q 1VQ5P 2LKIA 3GJNA 2AF8A 4U0BA 2KOPA 4CA3A 1QVGO 1K9MQ 2EHSA 1BAJA 4QNBA 1QVFO 2JYGA 2MR7A 1E6JP 2DNWA 2FQ2A 1VQNP 4XRQA 5F2OA 3G1IA 1ZMBA 1M6EX 2JU1A 2GYKA 3G1GA 4U0DA 1S72P 2KODA 2N6YA 2LF4A 1M6NA 1RNIA 2LTEA 3DS5A 3VRLC 1YITP 3LMOA 3RG6C 4IZ6A 5F2NA 1NQ4A 3HYBA 3OW2O 2CGQA 4MRTC 4R0MA 3CCRP 1VQ9P 2BUOA 1GXGA 2X2BA 3CD6P 1EOQA 1N8RQ 2PENA 3GZLA 4GR6A 2MF4A 2VLPA 1Z6MA 2L6EA 2QEXP 1YI2P 4U0CA 2XT1A 4COCA 2JYLA 2L0QA 2PEQA 4IPYA 3I56P 1YJWP 4XROA 2FQ0A 2KG6A 2M5RA 4U0AA 1VQ8P 2OTLP 2CQ8A 2MD9A 3CCLP 2JBGA 4F37A 2FVFA 5F2KA 1AYIA 3DS4A 1Q86Q 2N6ZA 3CC4P 3DS3A 1VKUA 3G0VA 3CMEP 1K8AQ 5KP8B 1HY8A 2PEJA 2Z46A 5EW5E 5HVCA 3DS2A 3CCEP 3H0DA 1YJNP 2GZIA 2GDWA 2K0DX 5DCKA 2K0XA 1HQBA 1QRJA 4H2XC 3DTJA 5HV8A 3G29A 2N98A 1FR2A 4NEOA 3CXCO 4QKOA 2EHTA 2GZJA 2L4BA 1CEIA 2K2QA 1MZ8A 4U0FA 2FQ1A 3CPWO 2M8NA 2JU2A 3EJDA 2MY5A 3G26A 1Q7YQ 5HGMA 1VQ4P 2L22A 3CCJP 3G4SP 2M8LA 1NJIQ 2KWLA 1VQMP 1GXHA 3CC2P 3G6EP 2AVAA 3U43A 3MGEA 3NY7B 4HKGA 1YIJP 4PH1A 2FVAA 2KW2A 2E1MA 1Q81Q 1VQLP 4H2YC 1E0HA 5KP6B 2GZEA 2VLOA 2FHSC 3B4QA 1KLPA 5HGOA 2KOQA 2XV6A 2MVVA 3CCUP 2KOSA 2EFJA 1M1KQ 1M74A 1ZNVA 5KP7B 2XZ0D 3M1MA 2NO8A 2WPTA 2N50A 2PEKA 3B5IA 5CZDB 3NTEA 5HGNA 3CCMP 3Q20A 1RO2A 2BHVA 2PEIA 4DG9A 1IUQA 5HGLA 2LIUA 2FAEA 1KC8Q 2KG8A 2PNGA 4COPA 2L9FA 1EMVA 2K92A 2VLNA 2FVEA 2FADA 2LIWA 2M8PA 1GPJA 3I55P 1YJ9P 2FACA 2KR5A 2EG5A 2JO0A 1RO0A 1AUMA 1KQSO 2LL8A 1YHQP 3GZMA 2CWOA 2LOLA 2GDYA 2JGPA 7CEIA 2PEMA 1VQKP 4H2WC 2LPKA 2ERHA 2AFEA 3CE7A 1OR5A 2KOOA 3CC7P 2AFDA 3WBHA 2DGYA 2LMLA 1DV5A 5I4TG 1Q82Q 3EJBA 2PY8A 4U0EA 1VQPP 3CCVP 1JJ2O 2KGCA 3DS1A 3DPHA 2K93A 1ACPA 3LRYA 1VHNA 2VLQA 4WYMA 1F80D 4UHPB 1L0HA 3EJEA 4XFXA 3H4EA 3CMAP 2K94A 2N5HA 1AF8A 2K0YA 2KG9A 5EJDA 2Z44A 1UNKA 2N5IA 2P9XA 2OTJP
chains in the Genus database with same CATH topology
2CG5B 2DNWA 2FQ2A 2N50A 2K0XA 1HQBA 1T8KA 5CZDB 2MR8A 4H2XC 5HV8A 2N98A 2JU1A 4NEOA 4DG9A 3RG2A 2LIUA 2FAEA 2KGAA 2KG8A 2EHTA 2PNGA 2N6YA 2L9FA 2L4BA 2K92A 2LTEA 4PWVB 2K2QA 2FVEA 2MVUA 2FADA 3LMOA 2LIWA 4IZ6A 2KORA 2FQ1A 2FACA 1NQ4A 2CGQA 2JU2A 2KR5A 4MRTC 4R0MA 4BPFA 3EJDA 2MY5A 4BPGA 2LL8A 3GZMA 2X2BA 2LOLA 2L22A 2GDYA 2QNWA 3GZLA 2JGPA 2MF4A 2KWLA 4H2WC 2LPKA 3CE7A 2AFEA 1OR5A 2AVAA 2L0QA 2ROQA 2KGEA 2KOOA 2FQ0A 2AFDA 2KG6A 2M5RA 2XZ1C 3NY7B 4HKGA 2LMLA 1X3OA 2CQ8A 2VSQA 2MD9A 1DV5A 2FVAA 2JQ4A 1DNYA 2GDXA 2FVFA 3EJBA 2KW2A 2CNRA 2KGCA 2N6ZA 2K93A 4H2YC 1ACPA 1L0IA 4PXHB 4BPHA 2KGDA 1VKUA 2LKIA 5KP6B 2AF8A 1F80D 5KP8B 1L0HA 3EJEA 1HY8A 2KOPA 2K94A 2N5HA 2FHSC 4CA3A 2K0YA 1AF8A 2KG9A 1KLPA 5HVCA 2KOQA 2EHSA 5EJDA 2MVVA 2KOSA 5KP7B 2GDWA 2N5IA 2XZ0D 2MR7A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2CG5 B;  2DNW A;  2FQ2 A;  2N50 A;  2K0X A;  1HQB A;  1T8K A;  5CZD B;  2MR8 A;  4H2X C;  5HV8 A;  2N98 A;  2JU1 A;  4NEO A;  4DG9 A;  3RG2 A;  2LIU A;  2FAE A;  2KGA A;  2KG8 A;  2EHT A;  2PNG A;  2N6Y A;  2L9F A;  2L4B A;  2K92 A;  2LTE A;  4PWV B;  2K2Q A;  2FVE A;  2MVU A;  2FAD A;  3LMO A;  2LIW A;  4IZ6 A;  2KOR A;  2FQ1 A;  2FAC A;  1NQ4 A;  2CGQ A;  2JU2 A;  2KR5 A;  4MRT C;  4R0M A;  4BPF A;  3EJD A;  2MY5 A;  4BPG A;  2LL8 A;  3GZM A;  2X2B A;  2LOL A;  2L22 A;  2GDY A;  2QNW A;  3GZL A;  2JGP A;  2MF4 A;  2KWL A;  4H2W C;  2LPK A;  3CE7 A;  2AFE A;  1OR5 A;  2AVA A;  2L0Q A;  2ROQ A;  2KGE A;  2KOO A;  2FQ0 A;  2AFD A;  2KG6 A;  2M5R A;  2XZ1 C;  3NY7 B;  4HKG A;  2LML A;  1X3O A;  2CQ8 A;  2VSQ A;  2MD9 A;  1DV5 A;  2FVA A;  2JQ4 A;  1DNY A;  2GDX A;  2FVF A;  3EJB A;  2KW2 A;  2CNR A;  2KGC A;  2N6Z A;  2K93 A;  4H2Y C;  1ACP A;  1L0I A;  4PXH B;  4BPH A;  2KGD A;  1VKU A;  2LKI A;  5KP6 B;  2AF8 A;  1F80 D;  5KP8 B;  1L0H A;  3EJE A;  1HY8 A;  2KOP A;  2K94 A;  2N5H A;  2FHS C;  4CA3 A;  2K0Y A;  1AF8 A;  2KG9 A;  1KLP A;  5HVC A;  2KOQ A;  2EHS A;  5EJD A;  2MVV A;  2KOS A;  5KP7 B;  2GDW A;  2N5I A;  2XZ0 D;  2MR7 A; 
#chains in the Genus database with same CATH topology
 1IMQ A;  2CG5 B;  5JPA A;  2OAR A;  1W2B O;  1T8K A;  2MR8 A;  3CCQ P;  4XFZ A;  4XFY A;  3H47 A;  2GZF A;  2XXM A;  3RG2 A;  3CCS P;  3G71 P;  2KGA A;  2GZG A;  4PH0 A;  2ONT A;  1UJZ A;  4PWV B;  2MVU A;  1VQO P;  1K30 A;  4M0I A;  2KOR A;  2K5X A;  5BS2 A;  2PEO A;  4BPF A;  1BXI A;  4BPG A;  3G21 A;  3HZQ A;  2QNW A;  3DS0 A;  1A8O A;  2QA4 P;  1VQ6 P;  3GKL C;  2JAZ A;  4GR2 A;  2EIA A;  1K73 Q;  2ROQ A;  2KGE A;  2XZ1 C;  5BS1 A;  1VQ7 P;  1X3O A;  2VSQ A;  1EIA A;  2JQ4 A;  1DNY A;  2GDX A;  1IMP A;  2CNR A;  1A43 A;  3P05 A;  3E2D A;  1KD1 Q;  1L0I A;  2Z45 A;  4PXH B;  2JB0 A;  4BPH A;  3G28 A;  2KGD A;  1D1D A;  1M90 Q;  1VQ5 P;  2LKI A;  3GJN A;  2AF8 A;  4U0B A;  2KOP A;  4CA3 A;  1QVG O;  1K9M Q;  2EHS A;  1BAJ A;  4QNB A;  1QVF O;  2JYG A;  2MR7 A;  1E6J P;  2DNW A;  2FQ2 A;  1VQN P;  4XRQ A;  5F2O A;  3G1I A;  1ZMB A;  1M6E X;  2JU1 A;  2GYK A;  3G1G A;  4U0D A;  1S72 P;  2KOD A;  2N6Y A;  2LF4 A;  1M6N A;  1RNI A;  2LTE A;  3DS5 A;  3VRL C;  1YIT P;  3LMO A;  3RG6 C;  4IZ6 A;  5F2N A;  1NQ4 A;  3HYB A;  3OW2 O;  2CGQ A;  4MRT C;  4R0M A;  3CCR P;  1VQ9 P;  2BUO A;  1GXG A;  2X2B A;  3CD6 P;  1EOQ A;  1N8R Q;  2PEN A;  3GZL A;  4GR6 A;  2MF4 A;  2VLP A;  1Z6M A;  2L6E A;  2QEX P;  1YI2 P;  4U0C A;  2XT1 A;  4COC A;  2JYL A;  2L0Q A;  2PEQ A;  4IPY A;  3I56 P;  1YJW P;  4XRO A;  2FQ0 A;  2KG6 A;  2M5R A;  4U0A A;  1VQ8 P;  2OTL P;  2CQ8 A;  2MD9 A;  3CCL P;  2JBG A;  4F37 A;  2FVF A;  5F2K A;  1AYI A;  3DS4 A;  1Q86 Q;  2N6Z A;  3CC4 P;  3DS3 A;  1VKU A;  3G0V A;  3CME P;  1K8A Q;  5KP8 B;  1HY8 A;  2PEJ A;  2Z46 A;  5EW5 E;  5HVC A;  3DS2 A;  3CCE P;  3H0D A;  1YJN P;  2GZI A;  2GDW A;  2K0D X;  5DCK A;  2K0X A;  1HQB A;  1QRJ A;  4H2X C;  3DTJ A;  5HV8 A;  3G29 A;  2N98 A;  1FR2 A;  4NEO A;  3CXC O;  4QKO A;  2EHT A;  2GZJ A;  2L4B A;  1CEI A;  2K2Q A;  1MZ8 A;  4U0F A;  2FQ1 A;  3CPW O;  2M8N A;  2JU2 A;  3EJD A;  2MY5 A;  3G26 A;  1Q7Y Q;  5HGM A;  1VQ4 P;  2L22 A;  3CCJ P;  3G4S P;  2M8L A;  1NJI Q;  2KWL A;  1VQM P;  1GXH A;  3CC2 P;  3G6E P;  2AVA A;  3U43 A;  3MGE A;  3NY7 B;  4HKG A;  1YIJ P;  4PH1 A;  2FVA A;  2KW2 A;  2E1M A;  1Q81 Q;  1VQL P;  4H2Y C;  1E0H A;  5KP6 B;  2GZE A;  2VLO A;  2FHS C;  3B4Q A;  1KLP A;  5HGO A;  2KOQ A;  2XV6 A;  2MVV A;  3CCU P;  2KOS A;  2EFJ A;  1M1K Q;  1M74 A;  1ZNV A;  5KP7 B;  2XZ0 D;  3M1M A;  2NO8 A;  2WPT A;  2N50 A;  2PEK A;  3B5I A;  5CZD B;  3NTE A;  5HGN A;  3CCM P;  3Q20 A;  1RO2 A;  2BHV A;  2PEI A;  4DG9 A;  1IUQ A;  5HGL A;  2LIU A;  2FAE A;  1KC8 Q;  2KG8 A;  2PNG A;  4COP A;  2L9F A;  1EMV A;  2K92 A;  2VLN A;  2FVE A;  2FAD A;  2LIW A;  2M8P A;  1GPJ A;  3I55 P;  1YJ9 P;  2FAC A;  2KR5 A;  2EG5 A;  2JO0 A;  1RO0 A;  1AUM A;  1KQS O;  2LL8 A;  1YHQ P;  3GZM A;  2CWO A;  2LOL A;  2GDY A;  2JGP A;  7CEI A;  2PEM A;  1VQK P;  4H2W C;  2LPK A;  2ERH A;  2AFE A;  3CE7 A;  1OR5 A;  2KOO A;  3CC7 P;  2AFD A;  3WBH A;  2DGY A;  2LML A;  1DV5 A;  5I4T G;  1Q82 Q;  3EJB A;  2PY8 A;  4U0E A;  1VQP P;  3CCV P;  1JJ2 O;  2KGC A;  3DS1 A;  3DPH A;  2K93 A;  1ACP A;  3LRY A;  1VHN A;  2VLQ A;  4WYM A;  1F80 D;  4UHP B;  1L0H A;  3EJE A;  4XFX A;  3H4E A;  3CMA P;  2K94 A;  2N5H A;  1AF8 A;  2K0Y A;  2KG9 A;  5EJD A;  2Z44 A;  1UNK A;  2N5I A;  2P9X A;  2OTJ P; 
#chains in the Genus database with same CATH homology
 2CG5 B;  2DNW A;  2FQ2 A;  2N50 A;  2K0X A;  1HQB A;  1T8K A;  5CZD B;  2MR8 A;  4H2X C;  5HV8 A;  2N98 A;  2JU1 A;  4NEO A;  4DG9 A;  3RG2 A;  2LIU A;  2FAE A;  2KGA A;  2KG8 A;  2EHT A;  2PNG A;  2N6Y A;  2L9F A;  2L4B A;  2K92 A;  2LTE A;  4PWV B;  2K2Q A;  2FVE A;  2MVU A;  2FAD A;  3LMO A;  2LIW A;  4IZ6 A;  2KOR A;  2FQ1 A;  2FAC A;  1NQ4 A;  2CGQ A;  2JU2 A;  2KR5 A;  4MRT C;  4R0M A;  4BPF A;  3EJD A;  2MY5 A;  4BPG A;  2LL8 A;  3GZM A;  2X2B A;  2LOL A;  2L22 A;  2GDY A;  2QNW A;  3GZL A;  2JGP A;  2MF4 A;  2KWL A;  4H2W C;  2LPK A;  3CE7 A;  2AFE A;  1OR5 A;  2AVA A;  2L0Q A;  2ROQ A;  2KGE A;  2KOO A;  2FQ0 A;  2AFD A;  2KG6 A;  2M5R A;  2XZ1 C;  3NY7 B;  4HKG A;  2LML A;  1X3O A;  2CQ8 A;  2VSQ A;  2MD9 A;  1DV5 A;  2FVA A;  2JQ4 A;  1DNY A;  2GDX A;  2FVF A;  3EJB A;  2KW2 A;  2CNR A;  2KGC A;  2N6Z A;  2K93 A;  4H2Y C;  1ACP A;  1L0I A;  4PXH B;  4BPH A;  2KGD A;  1VKU A;  2LKI A;  5KP6 B;  2AF8 A;  1F80 D;  5KP8 B;  1L0H A;  3EJE A;  1HY8 A;  2KOP A;  2K94 A;  2N5H A;  2FHS C;  4CA3 A;  2K0Y A;  1AF8 A;  2KG9 A;  1KLP A;  5HVC A;  2KOQ A;  2EHS A;  5EJD A;  2MVV A;  2KOS A;  5KP7 B;  2GDW A;  2N5I A;  2XZ0 D;  2MR7 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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