2CG5B

Structure of aminoadipate-semialdehyde dehydrogenase- phosphopantetheinyl transferase in complex with cytosolic acyl carrier protein and coenzyme a
Total Genus 19
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
19
sequence length
71
structure length
71
Chain Sequence
QRDLVEAVAHILGIRDLAAVNLDSSLADLGLDALMSVEVRQTLERELNLVLSVREVRQLTLRKLQELSSKA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Mechanism and Substrate Recognition of Human Holo Acp Synthase.
pubmed doi rcsb
molecule tags Transferase/hydrolase
source organism Homo sapiens
molecule keywords L-AMINOADIPATE-SEMIALDEHYDE DEHYDROGENASE-PHOSPHOPANTETHEINY
total genus 19
structure length 71
sequence length 71
ec nomenclature ec 1.1.1.100: 3-oxoacyl-[acyl-carrier-protein] reductase.
pdb deposition date 2006-02-27

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF00550 PP-binding Phosphopantetheine attachment site
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1200.10 Mainly Alpha Orthogonal Bundle Non-ribosomal Peptide Synthetase Peptidyl Carrier Protein; Chain A ACP-like 2cg5B00
4BPHA 2KGCA 2JU1A 2EHTA 1OR5A 3CE7A 3LMOA 3GZLA 1NQ4A 2N5IA 4R0MA 2CG5B 5EJDA 2FACA 2MD9A 1T8KA 2MVVA 4PXHB 1L0HA 2FQ2A 5HV8A 2GDXA 3EJBA 4H2XC 5CZDB 2K2QA 4NEOA 2GDWA 2FVAA 2AFEA 2K93A 4DG9A 5KP7B 2LOLA 4BPFA 2X2BA 2EHSA 2FVEA 2KGAA 2AVAA 2KR5A 1VKUA 2LL8A 2FVFA 2M5RA 2XZ1C 2N6YA 2PNGA 2KOSA 2N6ZA 1KLPA 1F80D 2LKIA 2CQ8A 2N98A 2LIUA 2FADA 2KGDA 1HY8A 4MRTC 3RG2A 2K0XA 2DNWA 2MVUA 4HKGA 1X3OA 2K94A 2AF8A 2JU2A 5KP8B 2KOPA 2FHSC 2FAEA 2KOOA 2L9FA 3EJEA 2JGPA 1L0IA 2LPKA 2KW2A 2LTEA 5HVCA 2FQ1A 2MF4A 2LIWA 2L0QA 2KG8A 2VSQA 1ACPA 4PWVB 4BPGA 2KOQA 1AF8A 2ROQA 2QNWA 2N50A 2KWLA 4H2WC 2CGQA 2FQ0A 2L4BA 3NY7B 2KGEA 2MY5A 2JQ4A 2AFDA 2MR7A 2KG6A 1HQBA 2MR8A 3EJDA 1DV5A 5KP6B 1DNYA 2LMLA 2L22A 3GZMA 2KG9A 4IZ6A 4H2YC 2K92A 2XZ0D 2GDYA 2K0YA 2CNRA 2N5HA 4CA3A 2KORA
chains in the Genus database with same CATH superfamily
2JU1A 2Z45A 3I56P 2QEXP 1OR5A 3GZLA 1QVFO 1NQ4A 2GZJA 2N5IA 1M6EX 5EJDA 2MD9A 4XRQA 1M90Q 3RG6C 1BXIA 5HV8A 3DPHA 2XXMA 4NEOA 2VLOA 2K93A 4BPFA 2Z46A 2BUOA 2LL8A 2XZ1C 1F80D 1YJWP 2LKIA 1VQLP 2XV6A 1D1DA 3G1GA 2K0XA 1EOQA 3G6EP 2JYGA 3G0VA 5KP8B 3HZQA 1GXGA 2PEQA 2JGPA 1IMPA 3G71P 4XROA 4U0BA 1YI2P 5HVCA 4M0IA 3CCRP 3U43A 2GZIA 2MF4A 4IPYA 2BHVA 2KG8A 2M8NA 4PWVB 3CCMP 5EW5E 3CCSP 2QNWA 2N50A 1VQKP 3LRYA 2L4BA 1K9MQ 1A8OA 2MR7A 1HQBA 1YJNP 1Z6MA 1IMQA 4H2YC 1IUQA 2GZFA 3GKLC 3CCLP 4COPA 3CCEP 2K0YA 2CNRA 1RO2A 5JPAA 2KORA 1VQOP 4BPHA 5HGNA 2KGCA 4F37A 3LMOA 2GZGA 1KQSO 2CG5B 3M1MA 3CD6P 3CCJP 3CPWO 2CWOA 2K2QA 2JB0A 5HGLA 2ONTA 7CEIA 2PEOA 5KP7B 3CMAP 1NJIQ 2FVEA 2PEIA 1VQ7P 2KODA 2ERHA 1A43A 2M5RA 5F2OA 2KOSA 2N6ZA 1VQ5P 2CQ8A 2N98A 5HGMA 2KGDA 3G4SP 2MVUA 2L6EA 3HYBA 2AF8A 2QA4P 2KOPA 3CMEP 2KOOA 3CC7P 1YJ9P 3DS1A 2LPKA 2LTEA 1UNKA 1Q82Q 1QVGO 2L0QA 1ACPA 3G1IA 4BPGA 2KOQA 1W2BO 4COCA 2PY8A 1AYIA 2JO0A 1KC8Q 2KWLA 2CGQA 2M8LA 1YITP 3H0DA 1FR2A 3NY7B 1YHQP 2JQ4A 2VLNA 2JYLA 5BS2A 3G26A 1DNYA 2KG9A 3G21A 2PEMA 3DS4A 4XFYA 3G29A 4U0AA 3DS5A 3B4QA 2DGYA 2EHTA 3G28A 1YIJP 5I4TG 4R0MA 4U0FA 1T8KA 4PXHB 3MGEA 1Q7YQ 4PH0A 2PENA 4QNBA 4U0EA 2GDXA 3EJBA 3H4EA 5CZDB 3CCVP 2GDWA 2AFEA 1K8AQ 2X2BA 4XFZA 3I55P 2KR5A 1RO0A 3DS2A 2FVFA 1UJZA 3DS0A 1KLPA 2EG5A 1MZ8A 3NTEA 2FADA 4MRTC 3RG2A 3CXCO 1VQPP 1E0HA 1KD1Q 4HKGA 1AUMA 2VLPA 1X3OA 2K94A 2JU2A 3E2DA 2FHSC 2FAEA 1VQ6P 1M6NA 3GJNA 1K73Q 1M1KQ 4GR2A 1Q86Q 1L0IA 2P9XA 2Z44A 2EIAA 2LIWA 3CCQP 2ROQA 1QRJA 2GYKA 1VHNA 2KGEA 2AFDA 1GPJA 3CC4P 4QKOA 2MR8A 3EJDA 3OW2O 1DV5A 2LMLA 1CEIA 2XZ0D 2N5HA 1VQMP 4CA3A 2LF4A 4WYMA 3Q20A 3CC2P 3CE7A 2WPTA 1EIAA 1ZNVA 1E6JP 2FACA 3WBHA 2MVVA 1L0HA 2FQ2A 1Q81Q 2K5XA 4H2XC 3DTJA 1N8RQ 1VQ8P 2FVAA 4PH1A 4DG9A 2LOLA 2JAZA 2EHSA 3P05A 1M74A 2KGAA 2AVAA 1VKUA 2N6YA 2PNGA 1VQ4P 2E1MA 2M8PA 4U0CA 1GXHA 2LIUA 1RNIA 1HY8A 2GZEA 2PEJA 2DNWA 2VLQA 2OTJP 1EMVA 2NO8A 3CCUP 2L9FA 3EJEA 1VQ9P 5BS1A 2OARA 2KW2A 2PEKA 2FQ1A 3B5IA 1K30A 1S72P 5DCKA 2OTLP 4GR6A 2XT1A 2VSQA 1VQNP 5HGOA 1JJ2O 1ZMBA 1AF8A 4H2WC 2FQ0A 4XFXA 2MY5A 2K0DX 2KG6A 5KP6B 2L22A 4IZ6A 3GZMA 2EFJA 5F2NA 3H47A 2JBGA 3DS3A 4U0DA 5F2KA 3VRLC 2K92A 4UHPB 2GDYA 1BAJA
chains in the Genus database with same CATH topology
4BPHA 2KGCA 2JU1A 2EHTA 1OR5A 3CE7A 3LMOA 3GZLA 1NQ4A 2N5IA 4R0MA 2CG5B 5EJDA 2FACA 2MD9A 1T8KA 2MVVA 4PXHB 1L0HA 2FQ2A 5HV8A 2GDXA 3EJBA 4H2XC 5CZDB 2K2QA 4NEOA 2GDWA 2FVAA 2AFEA 2K93A 4DG9A 5KP7B 2LOLA 4BPFA 2X2BA 2EHSA 2FVEA 2KGAA 2AVAA 2KR5A 1VKUA 2LL8A 2FVFA 2M5RA 2XZ1C 2N6YA 2PNGA 2KOSA 2N6ZA 1KLPA 1F80D 2LKIA 2CQ8A 2N98A 2LIUA 2FADA 2KGDA 1HY8A 4MRTC 3RG2A 2K0XA 2DNWA 2MVUA 4HKGA 1X3OA 2K94A 2AF8A 2JU2A 5KP8B 2KOPA 2FHSC 2FAEA 2KOOA 2L9FA 3EJEA 2JGPA 1L0IA 2LPKA 2KW2A 2LTEA 5HVCA 2FQ1A 2MF4A 2LIWA 2L0QA 2KG8A 2VSQA 1ACPA 4PWVB 4BPGA 2KOQA 1AF8A 2ROQA 2QNWA 2N50A 2KWLA 4H2WC 2CGQA 2FQ0A 2L4BA 3NY7B 2KGEA 2MY5A 2JQ4A 2AFDA 2MR7A 2KG6A 1HQBA 2MR8A 3EJDA 1DV5A 5KP6B 1DNYA 2LMLA 2L22A 3GZMA 2KG9A 4IZ6A 4H2YC 2K92A 2XZ0D 2GDYA 2K0YA 2CNRA 2N5HA 4CA3A 2KORA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4BPH A;  2KGC A;  2JU1 A;  2EHT A;  1OR5 A;  3CE7 A;  3LMO A;  3GZL A;  1NQ4 A;  2N5I A;  4R0M A;  2CG5 B;  5EJD A;  2FAC A;  2MD9 A;  1T8K A;  2MVV A;  4PXH B;  1L0H A;  2FQ2 A;  5HV8 A;  2GDX A;  3EJB A;  4H2X C;  5CZD B;  2K2Q A;  4NEO A;  2GDW A;  2FVA A;  2AFE A;  2K93 A;  4DG9 A;  5KP7 B;  2LOL A;  4BPF A;  2X2B A;  2EHS A;  2FVE A;  2KGA A;  2AVA A;  2KR5 A;  1VKU A;  2LL8 A;  2FVF A;  2M5R A;  2XZ1 C;  2N6Y A;  2PNG A;  2KOS A;  2N6Z A;  1KLP A;  1F80 D;  2LKI A;  2CQ8 A;  2N98 A;  2LIU A;  2FAD A;  2KGD A;  1HY8 A;  4MRT C;  3RG2 A;  2K0X A;  2DNW A;  2MVU A;  4HKG A;  1X3O A;  2K94 A;  2AF8 A;  2JU2 A;  5KP8 B;  2KOP A;  2FHS C;  2FAE A;  2KOO A;  2L9F A;  3EJE A;  2JGP A;  1L0I A;  2LPK A;  2KW2 A;  2LTE A;  5HVC A;  2FQ1 A;  2MF4 A;  2LIW A;  2L0Q A;  2KG8 A;  2VSQ A;  1ACP A;  4PWV B;  4BPG A;  2KOQ A;  1AF8 A;  2ROQ A;  2QNW A;  2N50 A;  2KWL A;  4H2W C;  2CGQ A;  2FQ0 A;  2L4B A;  3NY7 B;  2KGE A;  2MY5 A;  2JQ4 A;  2AFD A;  2MR7 A;  2KG6 A;  1HQB A;  2MR8 A;  3EJD A;  1DV5 A;  5KP6 B;  1DNY A;  2LML A;  2L22 A;  3GZM A;  2KG9 A;  4IZ6 A;  4H2Y C;  2K92 A;  2XZ0 D;  2GDY A;  2K0Y A;  2CNR A;  2N5H A;  4CA3 A;  2KOR A; 
#chains in the Genus database with same CATH topology
 2JU1 A;  2Z45 A;  3I56 P;  2QEX P;  1OR5 A;  3GZL A;  1QVF O;  1NQ4 A;  2GZJ A;  2N5I A;  1M6E X;  5EJD A;  2MD9 A;  4XRQ A;  1M90 Q;  3RG6 C;  1BXI A;  5HV8 A;  3DPH A;  2XXM A;  4NEO A;  2VLO A;  2K93 A;  4BPF A;  2Z46 A;  2BUO A;  2LL8 A;  2XZ1 C;  1F80 D;  1YJW P;  2LKI A;  1VQL P;  2XV6 A;  1D1D A;  3G1G A;  2K0X A;  1EOQ A;  3G6E P;  2JYG A;  3G0V A;  5KP8 B;  3HZQ A;  1GXG A;  2PEQ A;  2JGP A;  1IMP A;  3G71 P;  4XRO A;  4U0B A;  1YI2 P;  5HVC A;  4M0I A;  3CCR P;  3U43 A;  2GZI A;  2MF4 A;  4IPY A;  2BHV A;  2KG8 A;  2M8N A;  4PWV B;  3CCM P;  5EW5 E;  3CCS P;  2QNW A;  2N50 A;  1VQK P;  3LRY A;  2L4B A;  1K9M Q;  1A8O A;  2MR7 A;  1HQB A;  1YJN P;  1Z6M A;  1IMQ A;  4H2Y C;  1IUQ A;  2GZF A;  3GKL C;  3CCL P;  4COP A;  3CCE P;  2K0Y A;  2CNR A;  1RO2 A;  5JPA A;  2KOR A;  1VQO P;  4BPH A;  5HGN A;  2KGC A;  4F37 A;  3LMO A;  2GZG A;  1KQS O;  2CG5 B;  3M1M A;  3CD6 P;  3CCJ P;  3CPW O;  2CWO A;  2K2Q A;  2JB0 A;  5HGL A;  2ONT A;  7CEI A;  2PEO A;  5KP7 B;  3CMA P;  1NJI Q;  2FVE A;  2PEI A;  1VQ7 P;  2KOD A;  2ERH A;  1A43 A;  2M5R A;  5F2O A;  2KOS A;  2N6Z A;  1VQ5 P;  2CQ8 A;  2N98 A;  5HGM A;  2KGD A;  3G4S P;  2MVU A;  2L6E A;  3HYB A;  2AF8 A;  2QA4 P;  2KOP A;  3CME P;  2KOO A;  3CC7 P;  1YJ9 P;  3DS1 A;  2LPK A;  2LTE A;  1UNK A;  1Q82 Q;  1QVG O;  2L0Q A;  1ACP A;  3G1I A;  4BPG A;  2KOQ A;  1W2B O;  4COC A;  2PY8 A;  1AYI A;  2JO0 A;  1KC8 Q;  2KWL A;  2CGQ A;  2M8L A;  1YIT P;  3H0D A;  1FR2 A;  3NY7 B;  1YHQ P;  2JQ4 A;  2VLN A;  2JYL A;  5BS2 A;  3G26 A;  1DNY A;  2KG9 A;  3G21 A;  2PEM A;  3DS4 A;  4XFY A;  3G29 A;  4U0A A;  3DS5 A;  3B4Q A;  2DGY A;  2EHT A;  3G28 A;  1YIJ P;  5I4T G;  4R0M A;  4U0F A;  1T8K A;  4PXH B;  3MGE A;  1Q7Y Q;  4PH0 A;  2PEN A;  4QNB A;  4U0E A;  2GDX A;  3EJB A;  3H4E A;  5CZD B;  3CCV P;  2GDW A;  2AFE A;  1K8A Q;  2X2B A;  4XFZ A;  3I55 P;  2KR5 A;  1RO0 A;  3DS2 A;  2FVF A;  1UJZ A;  3DS0 A;  1KLP A;  2EG5 A;  1MZ8 A;  3NTE A;  2FAD A;  4MRT C;  3RG2 A;  3CXC O;  1VQP P;  1E0H A;  1KD1 Q;  4HKG A;  1AUM A;  2VLP A;  1X3O A;  2K94 A;  2JU2 A;  3E2D A;  2FHS C;  2FAE A;  1VQ6 P;  1M6N A;  3GJN A;  1K73 Q;  1M1K Q;  4GR2 A;  1Q86 Q;  1L0I A;  2P9X A;  2Z44 A;  2EIA A;  2LIW A;  3CCQ P;  2ROQ A;  1QRJ A;  2GYK A;  1VHN A;  2KGE A;  2AFD A;  1GPJ A;  3CC4 P;  4QKO A;  2MR8 A;  3EJD A;  3OW2 O;  1DV5 A;  2LML A;  1CEI A;  2XZ0 D;  2N5H A;  1VQM P;  4CA3 A;  2LF4 A;  4WYM A;  3Q20 A;  3CC2 P;  3CE7 A;  2WPT A;  1EIA A;  1ZNV A;  1E6J P;  2FAC A;  3WBH A;  2MVV A;  1L0H A;  2FQ2 A;  1Q81 Q;  2K5X A;  4H2X C;  3DTJ A;  1N8R Q;  1VQ8 P;  2FVA A;  4PH1 A;  4DG9 A;  2LOL A;  2JAZ A;  2EHS A;  3P05 A;  1M74 A;  2KGA A;  2AVA A;  1VKU A;  2N6Y A;  2PNG A;  1VQ4 P;  2E1M A;  2M8P A;  4U0C A;  1GXH A;  2LIU A;  1RNI A;  1HY8 A;  2GZE A;  2PEJ A;  2DNW A;  2VLQ A;  2OTJ P;  1EMV A;  2NO8 A;  3CCU P;  2L9F A;  3EJE A;  1VQ9 P;  5BS1 A;  2OAR A;  2KW2 A;  2PEK A;  2FQ1 A;  3B5I A;  1K30 A;  1S72 P;  5DCK A;  2OTL P;  4GR6 A;  2XT1 A;  2VSQ A;  1VQN P;  5HGO A;  1JJ2 O;  1ZMB A;  1AF8 A;  4H2W C;  2FQ0 A;  4XFX A;  2MY5 A;  2K0D X;  2KG6 A;  5KP6 B;  2L22 A;  4IZ6 A;  3GZM A;  2EFJ A;  5F2N A;  3H47 A;  2JBG A;  3DS3 A;  4U0D A;  5F2K A;  3VRL C;  2K92 A;  4UHP B;  2GDY A;  1BAJ A; 
#chains in the Genus database with same CATH homology
 4BPH A;  2KGC A;  2JU1 A;  2EHT A;  1OR5 A;  3CE7 A;  3LMO A;  3GZL A;  1NQ4 A;  2N5I A;  4R0M A;  2CG5 B;  5EJD A;  2FAC A;  2MD9 A;  1T8K A;  2MVV A;  4PXH B;  1L0H A;  2FQ2 A;  5HV8 A;  2GDX A;  3EJB A;  4H2X C;  5CZD B;  2K2Q A;  4NEO A;  2GDW A;  2FVA A;  2AFE A;  2K93 A;  4DG9 A;  5KP7 B;  2LOL A;  4BPF A;  2X2B A;  2EHS A;  2FVE A;  2KGA A;  2AVA A;  2KR5 A;  1VKU A;  2LL8 A;  2FVF A;  2M5R A;  2XZ1 C;  2N6Y A;  2PNG A;  2KOS A;  2N6Z A;  1KLP A;  1F80 D;  2LKI A;  2CQ8 A;  2N98 A;  2LIU A;  2FAD A;  2KGD A;  1HY8 A;  4MRT C;  3RG2 A;  2K0X A;  2DNW A;  2MVU A;  4HKG A;  1X3O A;  2K94 A;  2AF8 A;  2JU2 A;  5KP8 B;  2KOP A;  2FHS C;  2FAE A;  2KOO A;  2L9F A;  3EJE A;  2JGP A;  1L0I A;  2LPK A;  2KW2 A;  2LTE A;  5HVC A;  2FQ1 A;  2MF4 A;  2LIW A;  2L0Q A;  2KG8 A;  2VSQ A;  1ACP A;  4PWV B;  4BPG A;  2KOQ A;  1AF8 A;  2ROQ A;  2QNW A;  2N50 A;  2KWL A;  4H2W C;  2CGQ A;  2FQ0 A;  2L4B A;  3NY7 B;  2KGE A;  2MY5 A;  2JQ4 A;  2AFD A;  2MR7 A;  2KG6 A;  1HQB A;  2MR8 A;  3EJD A;  1DV5 A;  5KP6 B;  1DNY A;  2LML A;  2L22 A;  3GZM A;  2KG9 A;  4IZ6 A;  4H2Y C;  2K92 A;  2XZ0 D;  2GDY A;  2K0Y A;  2CNR A;  2N5H A;  4CA3 A;  2KOR A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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