2CJZA

Crystal structure of the c472s mutant of human protein tyrosine phosphatase ptpn5 (step, striatum enriched phosphatase) in complex with phosphotyrosine
Total Genus 96
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
96
sequence length
286
structure length
275
Chain Sequence
NLYFQSMSRVLQAEELHEKALDPFLLQAEFFEIPMNFVDPKEYDIPGLVRKNRYKTILPNPHSRVCLTSPDPDDPLSSYINANYIRGYGGEEKVYIATQGPIVSTVADFWRMVWQEHTPIIVMITTEYWPEEQVAYDGVEITVQKVIHTEDYRLRLISLKSEERGLKHYWFTSWPDQKTPDRAPPLLHLVREVEEAAQQEGPHCAPIIVHSSAGIGRTGCFIATSICCQQLRQEGVVDILKTTCQLRQDRGGMIQTCEQYQFVHHVMSLYEKQLS
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Large-Scale Structural Analysis of the Classical Human Protein Tyrosine Phosphatome.
pubmed doi rcsb
molecule keywords HUMAN PROTEIN TYROSINE PHOSPHATASE PTPN5
molecule tags Hydrolase
source organism Homo sapiens
total genus 96
structure length 275
sequence length 286
ec nomenclature ec 3.1.3.48: Protein-tyrosine-phosphatase.
pdb deposition date 2006-04-10

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00102 Y_phosphatase Protein-tyrosine phosphatase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.190.10 Alpha Beta Alpha-Beta Complex Protein-Tyrosine Phosphatase; Chain A Protein tyrosine phosphatase superfamily 2cjzA00
4GFVA 2MBCA 2ZN7A 3PS5A 5K9VA 5IBSA 3AWFA 1NNYA 5I6VA 1Q6SA 2E0TA 3QCNA 1YPTA 1YTNA 2OUDA 2NT2A 2C7SA 1C86A 2PT0A 2PI7A 4R30A 1PA9A 1OEMX 1U25A 1T4JA 4QBEA 1A5YA 1YGRA 3EB1A 1R6HA 3QCLA 2SHPA 5K25A 1WAXA 1I9TA 4RI4A 1PTVA 1EENA 4R0TA 2F6YA 5K24A 3A5KA 2GWOA 4OHHA 1PXHA 3RO1A 4KYQA 2VEUA 2CNFA 5KABA 1XRIA 3A5JA 4GRZA 2B07A 4OHDA 2M3VA 1T49A 1KAKA 1PH0A 2GJTA 2CNGA 3D42A 1J4XA 2HNQA 3EU0A 2A3KA 3M4UA 4WU3A 2G59A 1EEOA 1PTTA 1YWFA 1L8KA 3OMHA 1ZCLA 3QCMA 3RGQA 1Q6MA 3QCFA 2F6WA 1ONZA 1KAVA 4HRFA 4KYRA 3OLRA 3GXGA 2B3OA 1X24A 2CJZA 2Q47A 1G7GA 2B4OA 4RH9A 3S4EA 3MMJA 4GWFA 4JMJA 1FPZA 3O4SA 4RHGA 2FJMA 4PVGA 2YDUA 3F81A 2PA5A 3QCCA 2F6VA 4PYHA 5KA0A 3S3KA 5HDEA 2QDPA 3BRHA 3CM3A 5KAAA 4ICZA 1ONYA 2HCMA 1LYVA 1GWZA 1RXDA 3N0AA 2ESBA 3I80A 2B49A 2I5XA 2FH7A 2H4GA 2H4VA 1YN9A 3AWGA 1VHRA 3F99A 3AWEA 2I4EA 4OHEA 2F6FA 3QCBA 4MBBA 4I8NA 2DXPA 1C88A 2GP0A 4ERCA 2H02A 4GRYA 4HJPA 4HJQA 3U96A 2QEPA 2G6ZA 4QUNA 4QAHA 2C46A 2ZMMA 2VEXA 2QCJA 4H1OA 1OEVA 4Y2EA 4KI9A 3QKQA 3SMEA 3V0IA 2I1YA 1Q6JA 3D1HA 3LJ8A 3RGOA 3B7OA 2I6OA 3D44A 2H03A 3D1OA 3QCJA 3EMUA 2CM8A 2I42A 2IMGA 4J51A 5KA1A 5K22A 4D3RA 1D5RA 2HY3A 2RF6A 1NO6A 5AWXA 1YTSA 1G1HA 3BM8A 3S3EA 5MMZB 4BJOA 5EHRA 2Y2FA 1YTWA 3ZMQA 2B4SA 1QXKA 2CM7A 2QBPA 2F70A 4GFUA 2CMAA 3S3FA 2HC2A 4YR8B 2NT7A 1G1FA 3QCEA 2PBNA 1T48A 3V0EA 4AZ1A 2H04A 2I75A 1BZCA 2CM2A 2QCTA 4OHLA 3EZZA 3D9CA 3EAXA 2I4GA 3S3HA 2A8BA 2VEWA 5EHPA 4WTYA 4DGPA 1PTUA 2P4DA 1YZ4A 2QBQA 4B04A 2AZRA 2VEVA 1YGUA 1V3AA 1XXPA 3D1QA 4S0GA 1FPRA 1G1GA 4D3PA 2FJNA 3O4UA 3V0DA 1WRMA 1PYNA 2JJDA 1I9SA 2QBRA 5KA3A 2CFVA 2PQ5A 3BLUA 2NLKA 2I6IA 2CMBA 3ZM3A 2I3RA 2BZLA 1PTYA 1M3GA 5KA7A 1U24A 5KACA 2F46A 2I3UA 5M43A 1C87A 1G7FA 3F9BA 2AHSA 2F71A 2QDMA 2BV5A 3NMEA 2I6MA 3V0JA 2VEYA 4H34A 4DGXA 4RDDA 4NWGA 4ZRTA 3ZM1A 2HC1A 4GE2A 3QKPA 1BZHA 3ZV2A 4Y14A 4D3QA 4QUMA 1AAXA 1LQFA 4NYHA 3H2XA 5BX1A 1JLNA 1Q6NA 2B4PA 2R0BA 2NV5A 4JNBA 3V0FA 1ZC0A 2BGDA 2I6PA 2NTAA 1C84A 3GXHA 4WU2A 2HB1A 4YAAA 2PSZA 1Q6PA 2CMCA 5K9WA 1FQ1A 2QDCA 1L8GA 2HXPA 1P15A 4QAPA 5KA4A 3BLTA 2CNHA 4RH5A 4TVVA 3QCDA 3QCHA 3I7ZA 3QCGA 4NX8A 1XXVA 2J16A 2CM3A 1NWLA 2H4KA 1OHEA 1ECVA 1QZ0A 2I6JA 2QBSA 3QCIA 3RZ2A 1PA1A 3F41A 4R0SA 1G4WR 1NWEA 1Q1MA 5K23A 1NZ7A 1NL9A 1OEOX 2I4HA 1XM2A 3I36A 4GE6A 4OHIA 4JBCA 2BGEA 4IKCA 1SUGA 5KA2A 1MKPA 2F6ZA 3O3LA 1GFYA 2OC3A 3ZM0A 3QCKA 4RKKA 2HNPA 4QBWA 5KA9A 5BUGA 4WOHA 2J17A 1ZCKA 3MOWA 2Y96A 2CNEA 2F6TA 2B4UA 1JF7A 3O5XA 2P6XA 3S4OA 1G4US 1C85A 1OHCA 3MOZA 5LXQB 2NZ6A 1OEUA 5IBMA 2OZ5A 3CWEA 2J16B 1XBOA 4GS0A 2OOQA 3SR9A 1ZZWA 1YFOA 4RI5A 4NWFA 4ZN5A 5BZXA 5J8RA 1LARA 3V0GA 5BZZA 2HVLA 3V0HA 3ZM2A 1OETA 4GE5A 4BPCA 3F9AA 3O4TA 4ZI4A 1I57A 2CNIA 1OHDA 4JMKA 2Q05A 1Q6TA 1BZJA 5KADA 1WCHA 1U26A 1RPMA 1C83A 2WGPA 5GTJA 4Z6BA 1OESA 4NNDA 3ZMPA 2BIJA 5KA8A
chains in the Genus database with same CATH superfamily
4GFVA 2MBCA 2ZN7A 3PS5A 5K9VA 5IBSA 3AWFA 1NNYA 5I6VA 1Q6SA 2E0TA 3QCNA 1YPTA 1YTNA 2OUDA 2NT2A 2C7SA 1C86A 2PT0A 3LK7A 2PI7A 4R30A 2XJAA 4UAGA 1PA9A 1OEMX 1U25A 1GQQA 1T4JA 4QBEA 1A5YA 1YGRA 3EB1A 1R6HA 3QCLA 2SHPA 5K25A 1WAXA 1I9TA 1P3DA 4RI4A 1PTVA 1EENA 4R0TA 2F6YA 5K24A 1FGSA 3A5KA 2GWOA 3MVNA 4OHHA 1PXHA 3RO1A 3UAGA 4KYQA 2VTEA 2VEUA 2CNFA 3ZL8A 5KABA 1XRIA 3A5JA 4GRZA 2B07A 2GCBA 4OHDA 2M3VA 1T49A 1KAKA 1PH0A 2GJTA 2CNGA 3D42A 1J4XA 2HNQA 3EU0A 2JFFA 2Y67A 2A3KA 3M4UA 4WU3A 2G59A 1EEOA 1PTTA 1YWFA 1L8KA 3OMHA 1ZCLA 3QCMA 3RGQA 1W78A 1Q6MA 1W7KA 3QCFA 2F6WA 1ONZA 2WTZA 1KAVA 4HRFA 2UUPA 4KYRA 3OLRA 3GXGA 2B3OA 1X24A 2CJZA 2Q47A 1G7GA 2B4OA 4RH9A 3S4EA 3MMJA 4GWFA 2GC5A 4JMJA 1FPZA 3O4SA 1E8CA 4RHGA 2FJMA 4PVGA 2YDUA 2PA5A 3F81A 3QCCA 2F6VA 4PYHA 5KA0A 3S3KA 5HDEA 2QDPA 3BRHA 3CM3A 1UAGA 5KAAA 4ICZA 5A5EA 1ONYA 2HCMA 2X5OA 2JFGA 1LYVA 1GWZA 1RXDA 3N0AA 2ESBA 3I80A 2B49A 2I5XA 2FH7A 2H4GA 2H4VA 1YN9A 3AWGA 1VHRA 3F99A 3AWEA 2I4EA 4OHEA 2F6FA 3QCBA 4MBBA 2F00A 2DXPA 4I8NA 1C88A 2GP0A 4ERCA 2H02A 4GRYA 4HJPA 4HJQA 3U96A 2QEPA 2G6ZA 4QUNA 4QAHA 2C46A 2ZMMA 2VEXA 2QCJA 4H1OA 1OEVA 1EEHA 4Y2EA 4KI9A 4QDIA 3QKQA 3SMEA 3V0IA 2I1YA 1Q6JA 3D1HA 3LJ8A 3RGOA 3B7OA 2I6OA 3D44A 2H03A 3D1OA 3QCJA 3EMUA 2CM8A 2I42A 2IMGA 4J51A 5KA1A 5K22A 2VORA 4D3RA 1D5RA 2HY3A 2RF6A 1NO6A 5AWXA 3ZM6A 1YTSA 3BM8A 1G1HA 3S3EA 5MMZB 4BJOA 5EHRA 2Y2FA 1YTWA 3ZMQA 4CVKA 2B4SA 1QXKA 2CM7A 4HV4A 2QBPA 2F70A 4GFUA 2VOSA 2CMAA 3S3FA 4CVLA 2HC2A 4YR8B 2NT7A 4BUCA 1G1FA 3QCEA 2PBNA 1T48A 3V0EA 4AZ1A 2H04A 2I75A 1BZCA 2AM1A 2CM2A 2QCTA 4OHLA 4C13A 3EZZA 3D9CA 3EAXA 2I4GA 3S3HA 2A8BA 2UUOA 2VEWA 5EHPA 4WTYA 4DGPA 1PTUA 2P4DA 1YZ4A 2QBQA 4B04A 2AZRA 2VEVA 1YGUA 1V3AA 1XXPA 3D1QA 4S0GA 1FPRA 1G1GA 4D3PA 3HN7A 2FJNA 3O4UA 3V0DA 1WRMA 1PYNA 2JJDA 2Y1OA 1I9SA 2QBRA 5KA3A 2CFVA 2WJPA 2PQ5A 3BLUA 2NLKA 2I6IA 2CMBA 3ZM3A 2I3RA 2BZLA 1O5ZA 3ZM5A 1PTYA 1M3GA 5KA7A 1U24A 5KACA 2F46A 2XPCA 2I3UA 5M43A 1C87A 1G7FA 3F9BA 2AHSA 2F71A 2QDMA 4CVMA 2BV5A 1GQYA 3NMEA 2I6MA 3V0JA 2VEYA 4H34A 4DGXA 5A5FA 4RDDA 4NWGA 4ZRTA 3PYZA 3ZM1A 2HC1A 4GE2A 3QKPA 1BZHA 3ZV2A 4Y14A 2Y66A 4D3QA 4QUMA 1AAXA 1LQFA 4NYHA 3H2XA 4C12A 5BX1A 1E0DA 1JLNA 1Q6NA 2B4PA 2R0BA 2NV5A 4JNBA 1J6UA 1GG4A 3V0FA 1ZC0A 2BGDA 2I6PA 2NTAA 1C84A 4BUBA 3GXHA 4WU2A 2HB1A 4YAAA 2PSZA 1Q6PA 2CMCA 5K9WA 1FQ1A 2QDCA 1L8GA 2HXPA 1P15A 4QAPA 5KA4A 3BLTA 2CNHA 4RH5A 4TVVA 2GCAA 3N2AA 3QCDA 3QCHA 2AM2A 3I7ZA 3QCGA 4NX8A 1XXVA 2J16A 2CM3A 1NWLA 1P31A 2H4KA 1OHEA 1ECVA 1QZ0A 2I6JA 2QBSA 3QCIA 3RZ2A 3QCZA 1PA1A 3F41A 4R0SA 1JBWA 1G4WR 1NWEA 1Q1MA 5K23A 1NZ7A 1NL9A 1OEOX 2I4HA 1XM2A 3I36A 4GE6A 4OHIA 4JBCA 2BGEA 4IKCA 1SUGA 5KA2A 1MKPA 2Y68A 2F6ZA 3O3LA 1GFYA 2OC3A 3ZM0A 3QCKA 4RKKA 2HNPA 2JFHA 4QBWA 5KA9A 5BUGA 4WOHA 2J17A 1ZCKA 3MOWA 2GC6A 2Y96A 2CNEA 2F6TA 4QF5A 2B4UA 1JF7A 3O5XA 2P6XA 3S4OA 1G4US 1C85A 1OHCA 3MOZA 5LXQB 2NZ6A 1OEUA 5IBMA 2OZ5A 3CWEA 2J16B 1XBOA 4GS0A 2OOQA 3SR9A 1ZZWA 1YFOA 2VTDA 4RI5A 4NWFA 4ZN5A 2UAGA 5BZXA 5J8RA 1LARA 3V0GA 5BZZA 2HVLA 3V0HA 3ZM2A 3NRSA 1OETA 4ZIYA 4GE5A 4BPCA 3F9AA 3O4TA 4ZI4A 1I57A 2CNIA 1OHDA 4JMKA 2Q05A 1Q6TA 1BZJA 5KADA 1WCHA 1U26A 1RPMA 1C83A 2WGPA 5GTJA 4Z6BA 1OESA 4NNDA 3ZMPA 2BIJA 5KA8A 1JBVA
chains in the Genus database with same CATH topology
4GFVA 2MBCA 2ZN7A 3PS5A 5K9VA 5IBSA 3AWFA 1NNYA 5I6VA 1Q6SA 2E0TA 3QCNA 1YPTA 1YTNA 2OUDA 2NT2A 2C7SA 1C86A 2PT0A 2PI7A 4R30A 1PA9A 1OEMX 1U25A 1T4JA 4QBEA 1A5YA 1YGRA 3EB1A 1R6HA 3QCLA 2SHPA 5K25A 1WAXA 1I9TA 4RI4A 1PTVA 1EENA 4R0TA 2F6YA 5K24A 3A5KA 2GWOA 4OHHA 1PXHA 3RO1A 4KYQA 2VEUA 2CNFA 5KABA 1XRIA 3A5JA 4GRZA 2B07A 4OHDA 2M3VA 1T49A 1KAKA 1PH0A 2GJTA 2CNGA 3D42A 1J4XA 2HNQA 3EU0A 2A3KA 3M4UA 4WU3A 2G59A 1EEOA 1PTTA 1YWFA 1L8KA 3OMHA 1ZCLA 3QCMA 3RGQA 1Q6MA 3QCFA 2F6WA 1ONZA 1KAVA 4HRFA 4KYRA 3OLRA 3GXGA 2B3OA 1X24A 2CJZA 2Q47A 1G7GA 2B4OA 4RH9A 3S4EA 3MMJA 4GWFA 4JMJA 1FPZA 3O4SA 4RHGA 2FJMA 4PVGA 2YDUA 3F81A 2PA5A 3QCCA 2F6VA 4PYHA 5KA0A 3S3KA 5HDEA 2QDPA 3BRHA 3CM3A 5KAAA 4ICZA 1ONYA 2HCMA 1LYVA 1GWZA 1RXDA 3N0AA 2ESBA 3I80A 2B49A 2I5XA 2FH7A 2H4GA 2H4VA 1YN9A 3AWGA 1VHRA 3F99A 3AWEA 2I4EA 4OHEA 2F6FA 3QCBA 4MBBA 4I8NA 2DXPA 1C88A 2GP0A 4ERCA 2H02A 4GRYA 4HJPA 4HJQA 3U96A 2QEPA 2G6ZA 4QUNA 4QAHA 2C46A 2ZMMA 2VEXA 2QCJA 4H1OA 1OEVA 4Y2EA 4KI9A 3QKQA 3SMEA 3V0IA 2I1YA 1Q6JA 3D1HA 3LJ8A 3RGOA 3B7OA 2I6OA 3D44A 2H03A 3D1OA 3QCJA 3EMUA 2CM8A 2I42A 2IMGA 4J51A 5KA1A 5K22A 4D3RA 1D5RA 2HY3A 2RF6A 1NO6A 5AWXA 1YTSA 1G1HA 3BM8A 3S3EA 5MMZB 4BJOA 5EHRA 2Y2FA 1YTWA 3ZMQA 2B4SA 1QXKA 2CM7A 2QBPA 2F70A 4GFUA 2CMAA 3S3FA 2HC2A 4YR8B 2NT7A 1G1FA 3QCEA 2PBNA 1T48A 3V0EA 4AZ1A 2H04A 2I75A 1BZCA 2CM2A 2QCTA 4OHLA 3EZZA 3D9CA 3EAXA 2I4GA 3S3HA 2A8BA 2VEWA 5EHPA 4WTYA 4DGPA 1PTUA 2P4DA 1YZ4A 2QBQA 4B04A 2AZRA 2VEVA 1YGUA 1V3AA 1XXPA 3D1QA 4S0GA 1FPRA 1G1GA 4D3PA 2FJNA 3O4UA 3V0DA 1WRMA 1PYNA 2JJDA 1I9SA 2QBRA 5KA3A 2CFVA 2PQ5A 3BLUA 2NLKA 2I6IA 2CMBA 3ZM3A 2I3RA 2BZLA 1PTYA 1M3GA 5KA7A 1U24A 5KACA 2F46A 2I3UA 5M43A 1C87A 1G7FA 3F9BA 2AHSA 2F71A 2QDMA 2BV5A 3NMEA 2I6MA 3V0JA 2VEYA 4H34A 4DGXA 4RDDA 4NWGA 4ZRTA 3ZM1A 2HC1A 4GE2A 3QKPA 1BZHA 3ZV2A 4Y14A 4D3QA 4QUMA 1AAXA 1LQFA 4NYHA 3H2XA 5BX1A 1JLNA 1Q6NA 2B4PA 2R0BA 2NV5A 4JNBA 3V0FA 1ZC0A 2BGDA 2I6PA 2NTAA 1C84A 3GXHA 4WU2A 2HB1A 4YAAA 2PSZA 1Q6PA 2CMCA 5K9WA 1FQ1A 2QDCA 1L8GA 2HXPA 1P15A 4QAPA 5KA4A 3BLTA 2CNHA 4RH5A 4TVVA 3QCDA 3QCHA 3I7ZA 3QCGA 4NX8A 1XXVA 2J16A 2CM3A 1NWLA 2H4KA 1OHEA 1ECVA 1QZ0A 2I6JA 2QBSA 3QCIA 3RZ2A 1PA1A 3F41A 4R0SA 1G4WR 1NWEA 1Q1MA 5K23A 1NZ7A 1NL9A 1OEOX 2I4HA 1XM2A 3I36A 4GE6A 4OHIA 4JBCA 2BGEA 4IKCA 1SUGA 5KA2A 1MKPA 2F6ZA 3O3LA 1GFYA 2OC3A 3ZM0A 3QCKA 4RKKA 2HNPA 4QBWA 5KA9A 5BUGA 4WOHA 2J17A 1ZCKA 3MOWA 2Y96A 2CNEA 2F6TA 2B4UA 1JF7A 3O5XA 2P6XA 3S4OA 1G4US 1C85A 1OHCA 3MOZA 5LXQB 2NZ6A 1OEUA 5IBMA 2OZ5A 3CWEA 2J16B 1XBOA 4GS0A 2OOQA 3SR9A 1ZZWA 1YFOA 4RI5A 4NWFA 4ZN5A 5BZXA 5J8RA 1LARA 3V0GA 5BZZA 2HVLA 3V0HA 3ZM2A 1OETA 4GE5A 4BPCA 3F9AA 3O4TA 4ZI4A 1I57A 2CNIA 1OHDA 4JMKA 2Q05A 1Q6TA 1BZJA 5KADA 1WCHA 1U26A 1RPMA 1C83A 2WGPA 5GTJA 4Z6BA 1OESA 4NNDA 3ZMPA 2BIJA 5KA8A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4GFV A;  2MBC A;  2ZN7 A;  3PS5 A;  5K9V A;  5IBS A;  3AWF A;  1NNY A;  5I6V A;  1Q6S A;  2E0T A;  3QCN A;  1YPT A;  1YTN A;  2OUD A;  2NT2 A;  2C7S A;  1C86 A;  2PT0 A;  2PI7 A;  4R30 A;  1PA9 A;  1OEM X;  1U25 A;  1T4J A;  4QBE A;  1A5Y A;  1YGR A;  3EB1 A;  1R6H A;  3QCL A;  2SHP A;  5K25 A;  1WAX A;  1I9T A;  4RI4 A;  1PTV A;  1EEN A;  4R0T A;  2F6Y A;  5K24 A;  3A5K A;  2GWO A;  4OHH A;  1PXH A;  3RO1 A;  4KYQ A;  2VEU A;  2CNF A;  5KAB A;  1XRI A;  3A5J A;  4GRZ A;  2B07 A;  4OHD A;  2M3V A;  1T49 A;  1KAK A;  1PH0 A;  2GJT A;  2CNG A;  3D42 A;  1J4X A;  2HNQ A;  3EU0 A;  2A3K A;  3M4U A;  4WU3 A;  2G59 A;  1EEO A;  1PTT A;  1YWF A;  1L8K A;  3OMH A;  1ZCL A;  3QCM A;  3RGQ A;  1Q6M A;  3QCF A;  2F6W A;  1ONZ A;  1KAV A;  4HRF A;  4KYR A;  3OLR A;  3GXG A;  2B3O A;  1X24 A;  2CJZ A;  2Q47 A;  1G7G A;  2B4O A;  4RH9 A;  3S4E A;  3MMJ A;  4GWF A;  4JMJ A;  1FPZ A;  3O4S A;  4RHG A;  2FJM A;  4PVG A;  2YDU A;  3F81 A;  2PA5 A;  3QCC A;  2F6V A;  4PYH A;  5KA0 A;  3S3K A;  5HDE A;  2QDP A;  3BRH A;  3CM3 A;  5KAA A;  4ICZ A;  1ONY A;  2HCM A;  1LYV A;  1GWZ A;  1RXD A;  3N0A A;  2ESB A;  3I80 A;  2B49 A;  2I5X A;  2FH7 A;  2H4G A;  2H4V A;  1YN9 A;  3AWG A;  1VHR A;  3F99 A;  3AWE A;  2I4E A;  4OHE A;  2F6F A;  3QCB A;  4MBB A;  4I8N A;  2DXP A;  1C88 A;  2GP0 A;  4ERC A;  2H02 A;  4GRY A;  4HJP A;  4HJQ A;  3U96 A;  2QEP A;  2G6Z A;  4QUN A;  4QAH A;  2C46 A;  2ZMM A;  2VEX A;  2QCJ A;  4H1O A;  1OEV A;  4Y2E A;  4KI9 A;  3QKQ A;  3SME A;  3V0I A;  2I1Y A;  1Q6J A;  3D1H A;  3LJ8 A;  3RGO A;  3B7O A;  2I6O A;  3D44 A;  2H03 A;  3D1O A;  3QCJ A;  3EMU A;  2CM8 A;  2I42 A;  2IMG A;  4J51 A;  5KA1 A;  5K22 A;  4D3R A;  1D5R A;  2HY3 A;  2RF6 A;  1NO6 A;  5AWX A;  1YTS A;  1G1H A;  3BM8 A;  3S3E A;  5MMZ B;  4BJO A;  5EHR A;  2Y2F A;  1YTW A;  3ZMQ A;  2B4S A;  1QXK A;  2CM7 A;  2QBP A;  2F70 A;  4GFU A;  2CMA A;  3S3F A;  2HC2 A;  4YR8 B;  2NT7 A;  1G1F A;  3QCE A;  2PBN A;  1T48 A;  3V0E A;  4AZ1 A;  2H04 A;  2I75 A;  1BZC A;  2CM2 A;  2QCT A;  4OHL A;  3EZZ A;  3D9C A;  3EAX A;  2I4G A;  3S3H A;  2A8B A;  2VEW A;  5EHP A;  4WTY A;  4DGP A;  1PTU A;  2P4D A;  1YZ4 A;  2QBQ A;  4B04 A;  2AZR A;  2VEV A;  1YGU A;  1V3A A;  1XXP A;  3D1Q A;  4S0G A;  1FPR A;  1G1G A;  4D3P A;  2FJN A;  3O4U A;  3V0D A;  1WRM A;  1PYN A;  2JJD A;  1I9S A;  2QBR A;  5KA3 A;  2CFV A;  2PQ5 A;  3BLU A;  2NLK A;  2I6I A;  2CMB A;  3ZM3 A;  2I3R A;  2BZL A;  1PTY A;  1M3G A;  5KA7 A;  1U24 A;  5KAC A;  2F46 A;  2I3U A;  5M43 A;  1C87 A;  1G7F A;  3F9B A;  2AHS A;  2F71 A;  2QDM A;  2BV5 A;  3NME A;  2I6M A;  3V0J A;  2VEY A;  4H34 A;  4DGX A;  4RDD A;  4NWG A;  4ZRT A;  3ZM1 A;  2HC1 A;  4GE2 A;  3QKP A;  1BZH A;  3ZV2 A;  4Y14 A;  4D3Q A;  4QUM A;  1AAX A;  1LQF A;  4NYH A;  3H2X A;  5BX1 A;  1JLN A;  1Q6N A;  2B4P A;  2R0B A;  2NV5 A;  4JNB A;  3V0F A;  1ZC0 A;  2BGD A;  2I6P A;  2NTA A;  1C84 A;  3GXH A;  4WU2 A;  2HB1 A;  4YAA A;  2PSZ A;  1Q6P A;  2CMC A;  5K9W A;  1FQ1 A;  2QDC A;  1L8G A;  2HXP A;  1P15 A;  4QAP A;  5KA4 A;  3BLT A;  2CNH A;  4RH5 A;  4TVV A;  3QCD A;  3QCH A;  3I7Z A;  3QCG A;  4NX8 A;  1XXV A;  2J16 A;  2CM3 A;  1NWL A;  2H4K A;  1OHE A;  1ECV A;  1QZ0 A;  2I6J A;  2QBS A;  3QCI A;  3RZ2 A;  1PA1 A;  3F41 A;  4R0S A;  1G4W R;  1NWE A;  1Q1M A;  5K23 A;  1NZ7 A;  1NL9 A;  1OEO X;  2I4H A;  1XM2 A;  3I36 A;  4GE6 A;  4OHI A;  4JBC A;  2BGE A;  4IKC A;  1SUG A;  5KA2 A;  1MKP A;  2F6Z A;  3O3L A;  1GFY A;  2OC3 A;  3ZM0 A;  3QCK A;  4RKK A;  2HNP A;  4QBW A;  5KA9 A;  5BUG A;  4WOH A;  2J17 A;  1ZCK A;  3MOW A;  2Y96 A;  2CNE A;  2F6T A;  2B4U A;  1JF7 A;  3O5X A;  2P6X A;  3S4O A;  1G4U S;  1C85 A;  1OHC A;  3MOZ A;  5LXQ B;  2NZ6 A;  1OEU A;  5IBM A;  2OZ5 A;  3CWE A;  2J16 B;  1XBO A;  4GS0 A;  2OOQ A;  3SR9 A;  1ZZW A;  1YFO A;  4RI5 A;  4NWF A;  4ZN5 A;  5BZX A;  5J8R A;  1LAR A;  3V0G A;  5BZZ A;  2HVL A;  3V0H A;  3ZM2 A;  1OET A;  4GE5 A;  4BPC A;  3F9A A;  3O4T A;  4ZI4 A;  1I57 A;  2CNI A;  1OHD A;  4JMK A;  2Q05 A;  1Q6T A;  1BZJ A;  5KAD A;  1WCH A;  1U26 A;  1RPM A;  1C83 A;  2WGP A;  5GTJ A;  4Z6B A;  1OES A;  4NND A;  3ZMP A;  2BIJ A;  5KA8 A; 
#chains in the Genus database with same CATH topology
 4GFV A;  2MBC A;  2ZN7 A;  3PS5 A;  5K9V A;  5IBS A;  3AWF A;  1NNY A;  5I6V A;  1Q6S A;  2E0T A;  3QCN A;  1YPT A;  1YTN A;  2OUD A;  2NT2 A;  2C7S A;  1C86 A;  2PT0 A;  3LK7 A;  2PI7 A;  4R30 A;  2XJA A;  4UAG A;  1PA9 A;  1OEM X;  1U25 A;  1GQQ A;  1T4J A;  4QBE A;  1A5Y A;  1YGR A;  3EB1 A;  1R6H A;  3QCL A;  2SHP A;  5K25 A;  1WAX A;  1I9T A;  1P3D A;  4RI4 A;  1PTV A;  1EEN A;  4R0T A;  2F6Y A;  5K24 A;  1FGS A;  3A5K A;  2GWO A;  3MVN A;  4OHH A;  1PXH A;  3RO1 A;  3UAG A;  4KYQ A;  2VTE A;  2VEU A;  2CNF A;  3ZL8 A;  5KAB A;  1XRI A;  3A5J A;  4GRZ A;  2B07 A;  2GCB A;  4OHD A;  2M3V A;  1T49 A;  1KAK A;  1PH0 A;  2GJT A;  2CNG A;  3D42 A;  1J4X A;  2HNQ A;  3EU0 A;  2JFF A;  2Y67 A;  2A3K A;  3M4U A;  4WU3 A;  2G59 A;  1EEO A;  1PTT A;  1YWF A;  1L8K A;  3OMH A;  1ZCL A;  3QCM A;  3RGQ A;  1W78 A;  1Q6M A;  1W7K A;  3QCF A;  2F6W A;  1ONZ A;  2WTZ A;  1KAV A;  4HRF A;  2UUP A;  4KYR A;  3OLR A;  3GXG A;  2B3O A;  1X24 A;  2CJZ A;  2Q47 A;  1G7G A;  2B4O A;  4RH9 A;  3S4E A;  3MMJ A;  4GWF A;  2GC5 A;  4JMJ A;  1FPZ A;  3O4S A;  1E8C A;  4RHG A;  2FJM A;  4PVG A;  2YDU A;  2PA5 A;  3F81 A;  3QCC A;  2F6V A;  4PYH A;  5KA0 A;  3S3K A;  5HDE A;  2QDP A;  3BRH A;  3CM3 A;  1UAG A;  5KAA A;  4ICZ A;  5A5E A;  1ONY A;  2HCM A;  2X5O A;  2JFG A;  1LYV A;  1GWZ A;  1RXD A;  3N0A A;  2ESB A;  3I80 A;  2B49 A;  2I5X A;  2FH7 A;  2H4G A;  2H4V A;  1YN9 A;  3AWG A;  1VHR A;  3F99 A;  3AWE A;  2I4E A;  4OHE A;  2F6F A;  3QCB A;  4MBB A;  2F00 A;  2DXP A;  4I8N A;  1C88 A;  2GP0 A;  4ERC A;  2H02 A;  4GRY A;  4HJP A;  4HJQ A;  3U96 A;  2QEP A;  2G6Z A;  4QUN A;  4QAH A;  2C46 A;  2ZMM A;  2VEX A;  2QCJ A;  4H1O A;  1OEV A;  1EEH A;  4Y2E A;  4KI9 A;  4QDI A;  3QKQ A;  3SME A;  3V0I A;  2I1Y A;  1Q6J A;  3D1H A;  3LJ8 A;  3RGO A;  3B7O A;  2I6O A;  3D44 A;  2H03 A;  3D1O A;  3QCJ A;  3EMU A;  2CM8 A;  2I42 A;  2IMG A;  4J51 A;  5KA1 A;  5K22 A;  2VOR A;  4D3R A;  1D5R A;  2HY3 A;  2RF6 A;  1NO6 A;  5AWX A;  3ZM6 A;  1YTS A;  3BM8 A;  1G1H A;  3S3E A;  5MMZ B;  4BJO A;  5EHR A;  2Y2F A;  1YTW A;  3ZMQ A;  4CVK A;  2B4S A;  1QXK A;  2CM7 A;  4HV4 A;  2QBP A;  2F70 A;  4GFU A;  2VOS A;  2CMA A;  3S3F A;  4CVL A;  2HC2 A;  4YR8 B;  2NT7 A;  4BUC A;  1G1F A;  3QCE A;  2PBN A;  1T48 A;  3V0E A;  4AZ1 A;  2H04 A;  2I75 A;  1BZC A;  2AM1 A;  2CM2 A;  2QCT A;  4OHL A;  4C13 A;  3EZZ A;  3D9C A;  3EAX A;  2I4G A;  3S3H A;  2A8B A;  2UUO A;  2VEW A;  5EHP A;  4WTY A;  4DGP A;  1PTU A;  2P4D A;  1YZ4 A;  2QBQ A;  4B04 A;  2AZR A;  2VEV A;  1YGU A;  1V3A A;  1XXP A;  3D1Q A;  4S0G A;  1FPR A;  1G1G A;  4D3P A;  3HN7 A;  2FJN A;  3O4U A;  3V0D A;  1WRM A;  1PYN A;  2JJD A;  2Y1O A;  1I9S A;  2QBR A;  5KA3 A;  2CFV A;  2WJP A;  2PQ5 A;  3BLU A;  2NLK A;  2I6I A;  2CMB A;  3ZM3 A;  2I3R A;  2BZL A;  1O5Z A;  3ZM5 A;  1PTY A;  1M3G A;  5KA7 A;  1U24 A;  5KAC A;  2F46 A;  2XPC A;  2I3U A;  5M43 A;  1C87 A;  1G7F A;  3F9B A;  2AHS A;  2F71 A;  2QDM A;  4CVM A;  2BV5 A;  1GQY A;  3NME A;  2I6M A;  3V0J A;  2VEY A;  4H34 A;  4DGX A;  5A5F A;  4RDD A;  4NWG A;  4ZRT A;  3PYZ A;  3ZM1 A;  2HC1 A;  4GE2 A;  3QKP A;  1BZH A;  3ZV2 A;  4Y14 A;  2Y66 A;  4D3Q A;  4QUM A;  1AAX A;  1LQF A;  4NYH A;  3H2X A;  4C12 A;  5BX1 A;  1E0D A;  1JLN A;  1Q6N A;  2B4P A;  2R0B A;  2NV5 A;  4JNB A;  1J6U A;  1GG4 A;  3V0F A;  1ZC0 A;  2BGD A;  2I6P A;  2NTA A;  1C84 A;  4BUB A;  3GXH A;  4WU2 A;  2HB1 A;  4YAA A;  2PSZ A;  1Q6P A;  2CMC A;  5K9W A;  1FQ1 A;  2QDC A;  1L8G A;  2HXP A;  1P15 A;  4QAP A;  5KA4 A;  3BLT A;  2CNH A;  4RH5 A;  4TVV A;  2GCA A;  3N2A A;  3QCD A;  3QCH A;  2AM2 A;  3I7Z A;  3QCG A;  4NX8 A;  1XXV A;  2J16 A;  2CM3 A;  1NWL A;  1P31 A;  2H4K A;  1OHE A;  1ECV A;  1QZ0 A;  2I6J A;  2QBS A;  3QCI A;  3RZ2 A;  3QCZ A;  1PA1 A;  3F41 A;  4R0S A;  1JBW A;  1G4W R;  1NWE A;  1Q1M A;  5K23 A;  1NZ7 A;  1NL9 A;  1OEO X;  2I4H A;  1XM2 A;  3I36 A;  4GE6 A;  4OHI A;  4JBC A;  2BGE A;  4IKC A;  1SUG A;  5KA2 A;  1MKP A;  2Y68 A;  2F6Z A;  3O3L A;  1GFY A;  2OC3 A;  3ZM0 A;  3QCK A;  4RKK A;  2HNP A;  2JFH A;  4QBW A;  5KA9 A;  5BUG A;  4WOH A;  2J17 A;  1ZCK A;  3MOW A;  2GC6 A;  2Y96 A;  2CNE A;  2F6T A;  4QF5 A;  2B4U A;  1JF7 A;  3O5X A;  2P6X A;  3S4O A;  1G4U S;  1C85 A;  1OHC A;  3MOZ A;  5LXQ B;  2NZ6 A;  1OEU A;  5IBM A;  2OZ5 A;  3CWE A;  2J16 B;  1XBO A;  4GS0 A;  2OOQ A;  3SR9 A;  1ZZW A;  1YFO A;  2VTD A;  4RI5 A;  4NWF A;  4ZN5 A;  2UAG A;  5BZX A;  5J8R A;  1LAR A;  3V0G A;  5BZZ A;  2HVL A;  3V0H A;  3ZM2 A;  3NRS A;  1OET A;  4ZIY A;  4GE5 A;  4BPC A;  3F9A A;  3O4T A;  4ZI4 A;  1I57 A;  2CNI A;  1OHD A;  4JMK A;  2Q05 A;  1Q6T A;  1BZJ A;  5KAD A;  1WCH A;  1U26 A;  1RPM A;  1C83 A;  2WGP A;  5GTJ A;  4Z6B A;  1OES A;  4NND A;  3ZMP A;  2BIJ A;  5KA8 A;  1JBV A; 
#chains in the Genus database with same CATH homology
 4GFV A;  2MBC A;  2ZN7 A;  3PS5 A;  5K9V A;  5IBS A;  3AWF A;  1NNY A;  5I6V A;  1Q6S A;  2E0T A;  3QCN A;  1YPT A;  1YTN A;  2OUD A;  2NT2 A;  2C7S A;  1C86 A;  2PT0 A;  2PI7 A;  4R30 A;  1PA9 A;  1OEM X;  1U25 A;  1T4J A;  4QBE A;  1A5Y A;  1YGR A;  3EB1 A;  1R6H A;  3QCL A;  2SHP A;  5K25 A;  1WAX A;  1I9T A;  4RI4 A;  1PTV A;  1EEN A;  4R0T A;  2F6Y A;  5K24 A;  3A5K A;  2GWO A;  4OHH A;  1PXH A;  3RO1 A;  4KYQ A;  2VEU A;  2CNF A;  5KAB A;  1XRI A;  3A5J A;  4GRZ A;  2B07 A;  4OHD A;  2M3V A;  1T49 A;  1KAK A;  1PH0 A;  2GJT A;  2CNG A;  3D42 A;  1J4X A;  2HNQ A;  3EU0 A;  2A3K A;  3M4U A;  4WU3 A;  2G59 A;  1EEO A;  1PTT A;  1YWF A;  1L8K A;  3OMH A;  1ZCL A;  3QCM A;  3RGQ A;  1Q6M A;  3QCF A;  2F6W A;  1ONZ A;  1KAV A;  4HRF A;  4KYR A;  3OLR A;  3GXG A;  2B3O A;  1X24 A;  2CJZ A;  2Q47 A;  1G7G A;  2B4O A;  4RH9 A;  3S4E A;  3MMJ A;  4GWF A;  4JMJ A;  1FPZ A;  3O4S A;  4RHG A;  2FJM A;  4PVG A;  2YDU A;  3F81 A;  2PA5 A;  3QCC A;  2F6V A;  4PYH A;  5KA0 A;  3S3K A;  5HDE A;  2QDP A;  3BRH A;  3CM3 A;  5KAA A;  4ICZ A;  1ONY A;  2HCM A;  1LYV A;  1GWZ A;  1RXD A;  3N0A A;  2ESB A;  3I80 A;  2B49 A;  2I5X A;  2FH7 A;  2H4G A;  2H4V A;  1YN9 A;  3AWG A;  1VHR A;  3F99 A;  3AWE A;  2I4E A;  4OHE A;  2F6F A;  3QCB A;  4MBB A;  4I8N A;  2DXP A;  1C88 A;  2GP0 A;  4ERC A;  2H02 A;  4GRY A;  4HJP A;  4HJQ A;  3U96 A;  2QEP A;  2G6Z A;  4QUN A;  4QAH A;  2C46 A;  2ZMM A;  2VEX A;  2QCJ A;  4H1O A;  1OEV A;  4Y2E A;  4KI9 A;  3QKQ A;  3SME A;  3V0I A;  2I1Y A;  1Q6J A;  3D1H A;  3LJ8 A;  3RGO A;  3B7O A;  2I6O A;  3D44 A;  2H03 A;  3D1O A;  3QCJ A;  3EMU A;  2CM8 A;  2I42 A;  2IMG A;  4J51 A;  5KA1 A;  5K22 A;  4D3R A;  1D5R A;  2HY3 A;  2RF6 A;  1NO6 A;  5AWX A;  1YTS A;  1G1H A;  3BM8 A;  3S3E A;  5MMZ B;  4BJO A;  5EHR A;  2Y2F A;  1YTW A;  3ZMQ A;  2B4S A;  1QXK A;  2CM7 A;  2QBP A;  2F70 A;  4GFU A;  2CMA A;  3S3F A;  2HC2 A;  4YR8 B;  2NT7 A;  1G1F A;  3QCE A;  2PBN A;  1T48 A;  3V0E A;  4AZ1 A;  2H04 A;  2I75 A;  1BZC A;  2CM2 A;  2QCT A;  4OHL A;  3EZZ A;  3D9C A;  3EAX A;  2I4G A;  3S3H A;  2A8B A;  2VEW A;  5EHP A;  4WTY A;  4DGP A;  1PTU A;  2P4D A;  1YZ4 A;  2QBQ A;  4B04 A;  2AZR A;  2VEV A;  1YGU A;  1V3A A;  1XXP A;  3D1Q A;  4S0G A;  1FPR A;  1G1G A;  4D3P A;  2FJN A;  3O4U A;  3V0D A;  1WRM A;  1PYN A;  2JJD A;  1I9S A;  2QBR A;  5KA3 A;  2CFV A;  2PQ5 A;  3BLU A;  2NLK A;  2I6I A;  2CMB A;  3ZM3 A;  2I3R A;  2BZL A;  1PTY A;  1M3G A;  5KA7 A;  1U24 A;  5KAC A;  2F46 A;  2I3U A;  5M43 A;  1C87 A;  1G7F A;  3F9B A;  2AHS A;  2F71 A;  2QDM A;  2BV5 A;  3NME A;  2I6M A;  3V0J A;  2VEY A;  4H34 A;  4DGX A;  4RDD A;  4NWG A;  4ZRT A;  3ZM1 A;  2HC1 A;  4GE2 A;  3QKP A;  1BZH A;  3ZV2 A;  4Y14 A;  4D3Q A;  4QUM A;  1AAX A;  1LQF A;  4NYH A;  3H2X A;  5BX1 A;  1JLN A;  1Q6N A;  2B4P A;  2R0B A;  2NV5 A;  4JNB A;  3V0F A;  1ZC0 A;  2BGD A;  2I6P A;  2NTA A;  1C84 A;  3GXH A;  4WU2 A;  2HB1 A;  4YAA A;  2PSZ A;  1Q6P A;  2CMC A;  5K9W A;  1FQ1 A;  2QDC A;  1L8G A;  2HXP A;  1P15 A;  4QAP A;  5KA4 A;  3BLT A;  2CNH A;  4RH5 A;  4TVV A;  3QCD A;  3QCH A;  3I7Z A;  3QCG A;  4NX8 A;  1XXV A;  2J16 A;  2CM3 A;  1NWL A;  2H4K A;  1OHE A;  1ECV A;  1QZ0 A;  2I6J A;  2QBS A;  3QCI A;  3RZ2 A;  1PA1 A;  3F41 A;  4R0S A;  1G4W R;  1NWE A;  1Q1M A;  5K23 A;  1NZ7 A;  1NL9 A;  1OEO X;  2I4H A;  1XM2 A;  3I36 A;  4GE6 A;  4OHI A;  4JBC A;  2BGE A;  4IKC A;  1SUG A;  5KA2 A;  1MKP A;  2F6Z A;  3O3L A;  1GFY A;  2OC3 A;  3ZM0 A;  3QCK A;  4RKK A;  2HNP A;  4QBW A;  5KA9 A;  5BUG A;  4WOH A;  2J17 A;  1ZCK A;  3MOW A;  2Y96 A;  2CNE A;  2F6T A;  2B4U A;  1JF7 A;  3O5X A;  2P6X A;  3S4O A;  1G4U S;  1C85 A;  1OHC A;  3MOZ A;  5LXQ B;  2NZ6 A;  1OEU A;  5IBM A;  2OZ5 A;  3CWE A;  2J16 B;  1XBO A;  4GS0 A;  2OOQ A;  3SR9 A;  1ZZW A;  1YFO A;  4RI5 A;  4NWF A;  4ZN5 A;  5BZX A;  5J8R A;  1LAR A;  3V0G A;  5BZZ A;  2HVL A;  3V0H A;  3ZM2 A;  1OET A;  4GE5 A;  4BPC A;  3F9A A;  3O4T A;  4ZI4 A;  1I57 A;  2CNI A;  1OHD A;  4JMK A;  2Q05 A;  1Q6T A;  1BZJ A;  5KAD A;  1WCH A;  1U26 A;  1RPM A;  1C83 A;  2WGP A;  5GTJ A;  4Z6B A;  1OES A;  4NND A;  3ZMP A;  2BIJ A;  5KA8 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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