2CKAA

Solution structures of the brk domains of the human chromo helicase domain 7 and 8, reveals structural similarity with gyf domain suggesting a role in protein interaction
Total Genus 14
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
14
sequence length
58
structure length
58
Chain Sequence
LDVDLETRIPVINKVDGTLLVGEDAPRRAELEMWLQGHPEFAVDPRFLAYMEDRRKQK
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Solution Structures of the Brk Domains of the Human Chromo Helicase Domain 7 and 8, Reveals Structural Similarity with Gyf Domain Suggesting a Role in Protein Interaction
rcsb
molecule keywords CHROMODOMAIN-HELICASE-DNA-BINDING PROTEIN 8
molecule tags Hydrolase
source organism Homo sapiens
total genus 14
structure length 58
sequence length 58
ec nomenclature ec 3.6.4.12: DNA helicase.
pdb deposition date 2006-04-14

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF07533 BRK BRK domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.20.28.130 Mainly Beta Single Sheet Rubrerythrin, domain 2 Rubrerythrin, domain 2 2ckaA01
2V0FA 2CKAA 2CKCA 2V0EA
chains in the Genus database with same CATH superfamily
2ERJA 3PL5A 3HOYL 2ERSA 5M5XL 2O5JD 1YUZA 4AYBP 1OWBA 4BY1L 1WJVA 1S2ZA 3ZG6A 1E8JA 4A3JL 4JADA 1YK4A 1BFYA 1T9QA 2C6AA 3PKIA 1B13A 4C2M1 1PFUA 3FDJA 1R0FA 3H9BA 2HVYC 2JA5L 3PIO1 3S2HL 2XJUA 3LNLA 3FKIL 2WB1P 2BE5D 1R0IA 4AHYA 2CR8A 3WWLA 2J9UB 2JI2A 1PFYA 3H0GL 5GAEc 5MF6A 6RXNA 1LKOA 1S30A 4XGHA 1IROA 2WAQP 5H1Sc 1T9OA 1LTLA 2LCQA 4WFN1 2GMGA 1SFOL 5JVH1 5MFZA 1YUXA 2XJSA 4AR3A 3B08B 5GAHc 2RDVA 1B2JA 4A3EL 4RXNA 1VZHA 5JVG1 2MS3A 4ZN3B 5DM71 2YU9L 5IP9L 1TWAL 1RYQA 4AI1A 4Y52L 4V196 2KN9A 1RYTA 5AN9H 3HOXL 5IP7L 3J7Z1 3B0AB 3K35A 2XJPA 3HJWB 5C4JL 4AI2A 1T9PA 3IU3I 2EY4E 3PZAA 2JI3A 4TPUA 2KKDA 2ZIXA 2VUML 1CAAA 3S16L 2NYDA 1NNQA 3QQCE 5IYDL 3S1NL 2PPTA 3NFPI 1Y1WL 3LWOB 4AR4A 2M4VA 1BE7A 3GTQL 3QVDA 3PKJA 2QL0A 4C3IL 4AHWA 3PO2L 3LWRB 3KYWA 1BQ9A 5M5WL 2A69D 3LWQB 1TWHL 2XJVA 3GTGL 2M6PA 4K9FA 3A44A 4AI3A 1ODHA 2JA7L 5M5YL 2A68D 3K7AL 2VL6A 5AI2A 2HR5A 4TVMA 1B71A 1RDVA 3HOVL 4A3GL 2Z3QB 2A6HD 2AUSB 3GTLL 5C4XL 1BQ8A 1WCML 5FLML 1LKPA 1B2OA 2K2DA 4A3DL 5RXNA 3LWVB 4ME3A 2XJRA 3H3VM 2Z3RB 1TWGL 3RZOL 3HJYB 1QYBA 3PIP1 2RFKB 1PFVA 1I6HL 2PSMC 1P7PA 4BBSL 4LHLA 3PO3L 3GTPL 4B8CD 3H99A 5IYBL 1R0JA 4A3FL 5IYCL 3RZTA 1PFWA 3MSUA 1IRNA 2PYAA 1RDGA 3P2AA 1FHMA 4AHZA 4UY81 1YK5A 2PVXA 5FJ8L 2V3BB 3S1ML 1DVBA 1IU6A 4BXXL 1DX8A 2L0ZA 1IU5A 2R92L 5EIOC 5M3ML 1FHHA 4Y7NL 5GAGc 4GS7D 3I4ML 3JR7A 1VCXA 2R93L 8RXNA 1TWCL 3MQKB 3HOZL 2AYJA 4AR6A 5C3EL 3HOWL 1I50L 1YV1A 2E2HL 2V0FA 5AI3A 4ZN1B 4POGA 2XJQA 1QQTA 1RWDA 1VZGA 4A3BL 5MGNA 2AQCA 5IY0A 2R7ZL 3GTKL 1SMUA 2JA8L 4C3HL 1S24A 5GADc 3GTML 2JI1A 5K2ME 3KYUA 4A93L 3HKZP 5MFPA 2M4YA 1RB9A 2NVXL 3H9CA 4XXBB 3GTJL 3HAXC 1NXEA 3CQZL 4YWMA 2JA6L 2E2IL 2DSXA 1OWCA 1JYBA 4C3JL 4X6AL 5EINC 2V0EA 4BBRL 5MLC3 3HOUL 1H7VA 3M4OL 3KYYA 4A3KL 5C44L 4U671 1SMMA 3P8BA 3RYGA 1R9TL 4LHNA 3LWPB 3J7Y1 1TWFL 1Z92B 3S1QL 1PZXA 2PMZP 1SMWA 3S1RL 2E2JL 2Y0SP 3S14L 2B5ID 3S2DL 1BRFA 3KYXA 4JAGA 3I4NL 1CADA 2APOB 2NVYL 3S15L 1F4LA 7RXNA 4A3LL 3VPBE 4A3ML 5M3FL 4JAFA 2CKCA 2NVTL 4E6YA 1NXGA 3S17L 1R0HA 4G6BA 4A3CL 3GTOL 1LKMA 1K83L 2XJTA 5DM61 4AHXA 3WWNB 3SS2A 1QCVA 2H12A 2A6ED 1R0GA 1ZRPA 3M3YL 2NVQL 3LPEB 2C6BA 3KYVA 4A3IL 3RZ6A 4AR5A 2PVEA 3PWFA 3MPSA 2CKAA 3H97A 2B63L 2M6OA 1Y1VL 4QIWP 3RZDL 1I3QL 4POFA 4BY7L 1C09A 4AI0A 4YWLA 4JAEA 1VZIA 1IW7D
chains in the Genus database with same CATH topology
3KYYA 2ERJA 1R0JA 3IU3I 4U671 1SMMA 2ERSA 3P8BA 3RZTA 2O5JD 3RYGA 1YUZA 2JI3A 3PZAA 3MSUA 1IRNA 4LHNA 2PYAA 1OWBA 1RDGA 3P2AA 4TPUA 1FHMA 4AHZA 3J7Y1 4UY81 2KKDA 2ZIXA 1YK5A 1Z92B 1WJVA 2PVXA 1S2ZA 3ZG6A 1E8JA 2V3BB 1CAAA 1SMWA 4JADA 1DVBA 1YK4A 1BFYA 1T9QA 2C6AA 1IU6A 1DX8A 2L0ZA 1IU5A 3PKIA 2B5ID 1B13A 5EIOC 2NYDA 1NNQA 1R0FA 3QQCE 1BRFA 2PPTA 3NFPI 1FHHA 4AR4A 3KYXA 5GAGc 2M4VA 4GS7D 3PIO1 2XJUA 1BE7A 3LNLA 4JAGA 1CADA 3QVDA 2BE5D 1R0IA 1VCXA 2CR8A 3PKJA 4AHYA 3WWLA 2QL0A 2J9UB 8RXNA 4AHWA 2JI2A 3KYWA 2AYJA 4AR6A 5GAEc 1BQ9A 7RXNA 2A69D 6RXNA 5MF6A 1LKOA 3VPBE 2XJVA 1S30A 4XGHA 1IROA 1YV1A 2M6PA 4K9FA 2V0FA 3A44A 4JAFA 2CKCA 4E6YA 5AI3A 4AI3A 1ODHA 4ZN1B 5H1Sc 1T9OA 4POGA 1NXGA 1R0HA 1LTLA 2LCQA 4WFN1 4G6BA 2A68D 1LKMA 2GMGA 2XJTA 5JVH1 2XJQA 2VL6A 5DM61 5AI2A 4AHXA 1RWDA 1VZGA 2HR5A 5MFZA 4TVMA 1YUXA 3SS2A 2XJSA 1B71A 1QCVA 1RDVA 3WWNB 5MGNA 4AR3A 2H12A 3B08B 5IY0A 2A6ED 1R0GA 5GAHc 1SMUA 2Z3QB 2A6HD 2RDVA 1ZRPA 1B2JA 4RXNA 3LPEB 1S24A 5GADc 1BQ8A 2C6BA 1VZHA 5JVG1 1LKPA 3KYVA 2JI1A 2MS3A 4ZN3B 1B2OA 5K2ME 2K2DA 5DM71 3KYUA 3RZ6A 5RXNA 5MFPA 2M4YA 1RB9A 4AR5A 2PVEA 2XJRA 3MPSA 3PWFA 4ME3A 2Z3RB 1RYQA 2CKAA 4AI1A 4XXBB 1QYBA 3PIP1 2M6OA 4V196 1NXEA 2KN9A 1RYTA 4YWMA 5AN9H 3J7Z1 3B0AB 3K35A 2PSMC 1H7VA 2DSXA 4POFA 1OWCA 1JYBA 1C09A 5EINC 4LHLA 2XJPA 2V0EA 4AI0A 5MLC3 4YWLA 4JAEA 1VZIA 4B8CD 4AI2A 1T9PA 1IW7D
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2V0F A;  2CKA A;  2CKC A;  2V0E A; 
#chains in the Genus database with same CATH topology
 2ERJ A;  3PL5 A;  3HOY L;  2ERS A;  5M5X L;  2O5J D;  1YUZ A;  4AYB P;  1OWB A;  4BY1 L;  1WJV A;  1S2Z A;  3ZG6 A;  1E8J A;  4A3J L;  4JAD A;  1YK4 A;  1BFY A;  1T9Q A;  2C6A A;  3PKI A;  1B13 A;  4C2M 1;  1PFU A;  3FDJ A;  1R0F A;  3H9B A;  2HVY C;  2JA5 L;  3PIO 1;  3S2H L;  2XJU A;  3LNL A;  3FKI L;  2WB1 P;  2BE5 D;  1R0I A;  4AHY A;  2CR8 A;  3WWL A;  2J9U B;  2JI2 A;  1PFY A;  3H0G L;  5GAE c;  5MF6 A;  6RXN A;  1LKO A;  1S30 A;  4XGH A;  1IRO A;  2WAQ P;  5H1S c;  1T9O A;  1LTL A;  2LCQ A;  4WFN 1;  2GMG A;  1SFO L;  5JVH 1;  5MFZ A;  1YUX A;  2XJS A;  4AR3 A;  3B08 B;  5GAH c;  2RDV A;  1B2J A;  4A3E L;  4RXN A;  1VZH A;  5JVG 1;  2MS3 A;  4ZN3 B;  5DM7 1;  2YU9 L;  5IP9 L;  1TWA L;  1RYQ A;  4AI1 A;  4Y52 L;  4V19 6;  2KN9 A;  1RYT A;  5AN9 H;  3HOX L;  5IP7 L;  3J7Z 1;  3B0A B;  3K35 A;  2XJP A;  3HJW B;  5C4J L;  4AI2 A;  1T9P A;  3IU3 I;  2EY4 E;  3PZA A;  2JI3 A;  4TPU A;  2KKD A;  2ZIX A;  2VUM L;  1CAA A;  3S16 L;  2NYD A;  1NNQ A;  3QQC E;  5IYD L;  3S1N L;  2PPT A;  3NFP I;  1Y1W L;  3LWO B;  4AR4 A;  2M4V A;  1BE7 A;  3GTQ L;  3QVD A;  3PKJ A;  2QL0 A;  4C3I L;  4AHW A;  3PO2 L;  3LWR B;  3KYW A;  1BQ9 A;  5M5W L;  2A69 D;  3LWQ B;  1TWH L;  2XJV A;  3GTG L;  2M6P A;  4K9F A;  3A44 A;  4AI3 A;  1ODH A;  2JA7 L;  5M5Y L;  2A68 D;  3K7A L;  2VL6 A;  5AI2 A;  2HR5 A;  4TVM A;  1B71 A;  1RDV A;  3HOV L;  4A3G L;  2Z3Q B;  2A6H D;  2AUS B;  3GTL L;  5C4X L;  1BQ8 A;  1WCM L;  5FLM L;  1LKP A;  1B2O A;  2K2D A;  4A3D L;  5RXN A;  3LWV B;  4ME3 A;  2XJR A;  3H3V M;  2Z3R B;  1TWG L;  3RZO L;  3HJY B;  1QYB A;  3PIP 1;  2RFK B;  1PFV A;  1I6H L;  2PSM C;  1P7P A;  4BBS L;  4LHL A;  3PO3 L;  3GTP L;  4B8C D;  3H99 A;  5IYB L;  1R0J A;  4A3F L;  5IYC L;  3RZT A;  1PFW A;  3MSU A;  1IRN A;  2PYA A;  1RDG A;  3P2A A;  1FHM A;  4AHZ A;  4UY8 1;  1YK5 A;  2PVX A;  5FJ8 L;  2V3B B;  3S1M L;  1DVB A;  1IU6 A;  4BXX L;  1DX8 A;  2L0Z A;  1IU5 A;  2R92 L;  5EIO C;  5M3M L;  1FHH A;  4Y7N L;  5GAG c;  4GS7 D;  3I4M L;  3JR7 A;  1VCX A;  2R93 L;  8RXN A;  1TWC L;  3MQK B;  3HOZ L;  2AYJ A;  4AR6 A;  5C3E L;  3HOW L;  1I50 L;  1YV1 A;  2E2H L;  2V0F A;  5AI3 A;  4ZN1 B;  4POG A;  2XJQ A;  1QQT A;  1RWD A;  1VZG A;  4A3B L;  5MGN A;  2AQC A;  5IY0 A;  2R7Z L;  3GTK L;  1SMU A;  2JA8 L;  4C3H L;  1S24 A;  5GAD c;  3GTM L;  2JI1 A;  5K2M E;  3KYU A;  4A93 L;  3HKZ P;  5MFP A;  2M4Y A;  1RB9 A;  2NVX L;  3H9C A;  4XXB B;  3GTJ L;  3HAX C;  1NXE A;  3CQZ L;  4YWM A;  2JA6 L;  2E2I L;  2DSX A;  1OWC A;  1JYB A;  4C3J L;  4X6A L;  5EIN C;  2V0E A;  4BBR L;  5MLC 3;  3HOU L;  1H7V A;  3M4O L;  3KYY A;  4A3K L;  5C44 L;  4U67 1;  1SMM A;  3P8B A;  3RYG A;  1R9T L;  4LHN A;  3LWP B;  3J7Y 1;  1TWF L;  1Z92 B;  3S1Q L;  1PZX A;  2PMZ P;  1SMW A;  3S1R L;  2E2J L;  2Y0S P;  3S14 L;  2B5I D;  3S2D L;  1BRF A;  3KYX A;  4JAG A;  3I4N L;  1CAD A;  2APO B;  2NVY L;  3S15 L;  1F4L A;  7RXN A;  4A3L L;  3VPB E;  4A3M L;  5M3F L;  4JAF A;  2CKC A;  2NVT L;  4E6Y A;  1NXG A;  3S17 L;  1R0H A;  4G6B A;  4A3C L;  3GTO L;  1LKM A;  1K83 L;  2XJT A;  5DM6 1;  4AHX A;  3WWN B;  3SS2 A;  1QCV A;  2H12 A;  2A6E D;  1R0G A;  1ZRP A;  3M3Y L;  2NVQ L;  3LPE B;  2C6B A;  3KYV A;  4A3I L;  3RZ6 A;  4AR5 A;  2PVE A;  3PWF A;  3MPS A;  2CKA A;  3H97 A;  2B63 L;  2M6O A;  1Y1V L;  4QIW P;  3RZD L;  1I3Q L;  4POF A;  4BY7 L;  1C09 A;  4AI0 A;  4YWL A;  4JAE A;  1VZI A;  1IW7 D; 
#chains in the Genus database with same CATH homology
 3KYY A;  2ERJ A;  1R0J A;  3IU3 I;  4U67 1;  1SMM A;  2ERS A;  3P8B A;  3RZT A;  2O5J D;  3RYG A;  1YUZ A;  2JI3 A;  3PZA A;  3MSU A;  1IRN A;  4LHN A;  2PYA A;  1OWB A;  1RDG A;  3P2A A;  4TPU A;  1FHM A;  4AHZ A;  3J7Y 1;  4UY8 1;  2KKD A;  2ZIX A;  1YK5 A;  1Z92 B;  1WJV A;  2PVX A;  1S2Z A;  3ZG6 A;  1E8J A;  2V3B B;  1CAA A;  1SMW A;  4JAD A;  1DVB A;  1YK4 A;  1BFY A;  1T9Q A;  2C6A A;  1IU6 A;  1DX8 A;  2L0Z A;  1IU5 A;  3PKI A;  2B5I D;  1B13 A;  5EIO C;  2NYD A;  1NNQ A;  1R0F A;  3QQC E;  1BRF A;  2PPT A;  3NFP I;  1FHH A;  4AR4 A;  3KYX A;  5GAG c;  2M4V A;  4GS7 D;  3PIO 1;  2XJU A;  1BE7 A;  3LNL A;  4JAG A;  1CAD A;  3QVD A;  2BE5 D;  1R0I A;  1VCX A;  2CR8 A;  3PKJ A;  4AHY A;  3WWL A;  2QL0 A;  2J9U B;  8RXN A;  4AHW A;  2JI2 A;  3KYW A;  2AYJ A;  4AR6 A;  5GAE c;  1BQ9 A;  7RXN A;  2A69 D;  6RXN A;  5MF6 A;  1LKO A;  3VPB E;  2XJV A;  1S30 A;  4XGH A;  1IRO A;  1YV1 A;  2M6P A;  4K9F A;  2V0F A;  3A44 A;  4JAF A;  2CKC A;  4E6Y A;  5AI3 A;  4AI3 A;  1ODH A;  4ZN1 B;  5H1S c;  1T9O A;  4POG A;  1NXG A;  1R0H A;  1LTL A;  2LCQ A;  4WFN 1;  4G6B A;  2A68 D;  1LKM A;  2GMG A;  2XJT A;  5JVH 1;  2XJQ A;  2VL6 A;  5DM6 1;  5AI2 A;  4AHX A;  1RWD A;  1VZG A;  2HR5 A;  5MFZ A;  4TVM A;  1YUX A;  3SS2 A;  2XJS A;  1B71 A;  1QCV A;  1RDV A;  3WWN B;  5MGN A;  4AR3 A;  2H12 A;  3B08 B;  5IY0 A;  2A6E D;  1R0G A;  5GAH c;  1SMU A;  2Z3Q B;  2A6H D;  2RDV A;  1ZRP A;  1B2J A;  4RXN A;  3LPE B;  1S24 A;  5GAD c;  1BQ8 A;  2C6B A;  1VZH A;  5JVG 1;  1LKP A;  3KYV A;  2JI1 A;  2MS3 A;  4ZN3 B;  1B2O A;  5K2M E;  2K2D A;  5DM7 1;  3KYU A;  3RZ6 A;  5RXN A;  5MFP A;  2M4Y A;  1RB9 A;  4AR5 A;  2PVE A;  2XJR A;  3MPS A;  3PWF A;  4ME3 A;  2Z3R B;  1RYQ A;  2CKA A;  4AI1 A;  4XXB B;  1QYB A;  3PIP 1;  2M6O A;  4V19 6;  1NXE A;  2KN9 A;  1RYT A;  4YWM A;  5AN9 H;  3J7Z 1;  3B0A B;  3K35 A;  2PSM C;  1H7V A;  2DSX A;  4POF A;  1OWC A;  1JYB A;  1C09 A;  5EIN C;  4LHL A;  2XJP A;  2V0E A;  4AI0 A;  5MLC 3;  4YWL A;  4JAE A;  1VZI A;  4B8C D;  4AI2 A;  1T9P A;  1IW7 D; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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