2CKCA

Solution structures of the brk domains of the human chromo helicase domain 7 and 8, reveals structural similarity with gyf domain suggesting a role in protein interaction
Total Genus 9
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
9
sequence length
60
structure length
60
Chain Sequence
LDPDTRIPVINLEDGTRLVGEDAPKNKDLVEWLKLHPTYTVDMPSYVPKNADVLFSSFQK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Solution Structures of the Brk Domains of the Human Chromo Helicase Domain 7 and 8, Reveals Structural Similarity with Gyf Domain Suggesting a Role in Protein Interaction
rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords CHROMODOMAIN-HELICASE-DNA-BINDING PROTEIN 7
total genus 9
structure length 60
sequence length 60
ec nomenclature ec 3.6.4.12: DNA helicase.
pdb deposition date 2006-04-14

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF07533 BRK BRK domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.20.28.130 Mainly Beta Single Sheet Rubrerythrin, domain 2 Rubrerythrin, domain 2 2ckcA00
2V0EA 2CKAA 2V0FA 2CKCA
chains in the Genus database with same CATH superfamily
3PL5A 2HR5A 3PKJA 3LWVB 4A93L 1R9TL 1BFYA 1BQ9A 3H9CA 4A3GL 2QL0A 1RDGA 3HOXL 3P2AA 2PVXA 2Y0SP 4ME3A 2ERJA 4QIWP 2M4VA 3QQCE 4A3JL 4C2M1 2YU9L 1CADA 2CKCA 3H97A 2J9UB 3B0AB 2VL6A 5MF6A 1BE7A 1YK5A 6RXNA 5H1Sc 2MS3A 3PKIA 3RZTA 5GAHc 5GAEc 4K9FA 2APOB 2AQCA 4G6BA 1LKMA 1H7VA 3S2HL 3HAXC 3MQKB 1PFWA 4JAGA 1RB9A 4A3CL 3S1RL 2JI3A 4WFN1 3KYYA 4BXXL 4ZN3B 5M5WL 3FDJA 1Y1WL 2CKAA 1R0FA 3HOZL 3FKIL 1PZXA 5DM71 3GTPL 3M4OL 1F4LA 4A3IL 3HOYL 1NXEA 5K2ME 2NVYL 1PFYA 5AN9H 3GTOL 2A69D 3M3YL 1B13A 2VUML 3PIO1 4XXBB 4POFA 4LHNA 1RWDA 4V196 5C44L 1B2JA 3I4NL 2JA7L 5M5XL 2AYJA 2O5JD 1TWCL 3HOVL 5JVH1 1Z92B 2XJTA 4GS7D 3S1QL 3MPSA 1OWBA 5MLC3 1T9QA 2NVTL 5IYCL 2Z3QB 1RYTA 5IY0A 5IYBL 5GADc 5MGNA 4A3ML 2BE5D 3LWPB 7RXNA 3S16L 2XJSA 5EIOC 3ZG6A 3SS2A 3NFPI 5AI3A 4BBRL 3PZAA 3QVDA 3S14L 3KYWA 4AR3A 2NVXL 2NVQL 3VPBE 1RDVA 1SFOL 2GMGA 8RXNA 5M5YL 1CAAA 1T9OA 4A3FL 1DVBA 2HVYC 3GTML 4Y52L 1IU5A 3KYXA 3J7Z1 3K7AL 1LKPA 2JI2A 1LTLA 1I50L 5GAGc 3LPEB 1ODHA 3KYVA 2PMZP 1ZRPA 5FJ8L 2ZIXA 2E2JL 3S17L 4E6YA 2B5ID 3GTLL 1TWHL 2B63L 2A68D 1VZHA 3HJYB 3RZOL 4AI2A 4ZN1B 3IU3I 4BBSL 3WWNB 1PFUA 3MSUA 2RDVA 1R0HA 2KN9A 2V3BB 2XJQA 1VZIA 4AI1A 2PVEA 5MFZA 1TWAL 5C4XL 5C3EL 5MFPA 3P8BA 4AI3A 1BRFA 2EY4E 5C4JL 1R0IA 4X6AL 1VCXA 1OWCA 3PWFA 3GTJL 5IYDL 5FLML 2L0ZA 3WWLA 2ERSA 3K35A 1YUXA 4AR4A 1QYBA 2A6ED 2AUSB 4BY7L 2XJPA 2RFKB 1I6HL 3KYUA 4JADA 5M3ML 1E8JA 4TPUA 3S2DL 4A3LL 2H12A 3HKZP 4LHLA 2C6BA 1DX8A 2V0FA 5DM61 1LKOA 4TVMA 1WJVA 2XJVA 2Z3RB 4XGHA 2M6PA 1NXGA 4A3DL 1SMMA 1FHHA 3HOUL 1B2OA 3B08B 2PPTA 3LWRB 3LNLA 1PFVA 1SMUA 4YWMA 2KKDA 1S2ZA 4AHXA 3LWOB 3S1ML 2V0EA 2PYAA 3I4ML 1IROA 2JA5L 4U671 2JA6L 3PIP1 1FHMA 3A44A 2E2IL 4Y7NL 2R93L 4AYBP 1WCML 2C6AA 1YV1A 1R0JA 4A3BL 4JAFA 3J7Y1 2XJRA 1IW7D 1I3QL 5IP9L 1C09A 4C3HL 3PO2L 2PSMC 4AI0A 1S24A 4AR6A 1BQ8A 2K2DA 1Y1VL 1TWGL 2WAQP 3GTKL 1VZGA 3JR7A 2E2HL 2DSXA 3RZ6A 1QQTA 4RXNA 3H0GL 4C3JL 3GTQL 4JAEA 1QCVA 5JVG1 2M6OA 3HOWL 2M4YA 4AHWA 3H99A 4AHYA 2R7ZL 4POGA 1IRNA 2CR8A 1YUZA 5IP7L 2A6HD 1SMWA 1K83L 1R0GA 5AI2A 5M3FL 3S1NL 2R92L 2LCQA 4A3KL 1B71A 3H9BA 4BY1L 1T9PA 1P7PA 1NNQA 1IU6A 4AR5A 2XJUA 3LWQB 4AHZA 3RZDL 3S15L 5EINC 2JI1A 2NYDA 4C3IL 1YK4A 2JA8L 4UY81 1RYQA 4YWLA 4A3EL 3GTGL 3H3VM 2WB1P 1TWFL 3HJWB 3PO3L 5RXNA 4B8CD 1JYBA 3RYGA 3CQZL 1S30A
chains in the Genus database with same CATH topology
5MFPA 1C09A 3P8BA 4AI3A 2HR5A 1BRFA 1B2JA 2PSMC 1R0IA 3PKJA 4AI0A 1VCXA 1OWCA 1S24A 3PWFA 1BFYA 1BQ9A 2L0ZA 4AR6A 3WWLA 2ERSA 1BQ8A 3K35A 2K2DA 1YUXA 4AR4A 2QL0A 1QYBA 2AYJA 2O5JD 1RDGA 2A6ED 1VZGA 3P2AA 5JVH1 1Z92B 2PVXA 4ME3A 2ERJA 2XJPA 2M4VA 2XJTA 3QQCE 4GS7D 3MPSA 1OWBA 5MLC3 1T9QA 3KYUA 2CKCA 1CADA 2DSXA 3RZ6A 2J9UB 3B0AB 4JADA 2VL6A 5MF6A 1BE7A 4RXNA 1YK5A 2Z3QB 1RYTA 4TPUA 6RXNA 1E8JA 5IY0A 4JAEA 1QCVA 5H1Sc 5GADc 5MGNA 2MS3A 3PKIA 5JVG1 2BE5D 2H12A 2M6OA 3RZTA 2M4YA 7RXNA 5GAHc 5GAEc 2XJSA 4LHLA 4AHWA 2C6BA 4AHYA 4K9FA 5EIOC 4POGA 1DX8A 2V0FA 3ZG6A 5DM61 1IRNA 1LKOA 4TVMA 2CR8A 1WJVA 4G6BA 3SS2A 3NFPI 5AI3A 1LKMA 1YUZA 2XJVA 1H7VA 2Z3RB 4XGHA 2M6PA 3PZAA 2A6HD 1NXGA 1SMWA 3QVDA 3KYWA 4AR3A 1R0GA 1SMMA 1FHHA 5AI2A 3VPBE 1B2OA 2LCQA 1RDVA 4JAGA 1RB9A 2GMGA 3B08B 8RXNA 2PPTA 2JI3A 1B71A 4WFN1 1T9PA 1CAAA 1T9OA 3KYYA 1DVBA 3LNLA 1SMUA 4ZN3B 1IU5A 3KYXA 4YWMA 3J7Z1 1LKPA 2KKDA 1NNQA 1S2ZA 2CKAA 1IU6A 2JI2A 4AHXA 4AR5A 1LTLA 2XJUA 1R0FA 5GAGc 3LPEB 2V0EA 2PYAA 4AHZA 3KYVA 5DM71 1ODHA 5EINC 1ZRPA 1IROA 2JI1A 2NYDA 2ZIXA 4U671 3PIP1 1FHMA 3A44A 1YK4A 4E6YA 2B5ID 1NXEA 1VZHA 2A68D 5K2ME 4AI2A 2C6AA 3IU3I 1RYQA 4ZN1B 4UY81 1YV1A 3WWNB 4YWLA 5AN9H 2A69D 3MSUA 2RDVA 1R0HA 1B13A 1R0JA 2KN9A 3PIO1 2V3BB 4JAFA 2XJQA 1VZIA 4XXBB 4AI1A 3J7Y1 4POFA 4LHNA 5RXNA 2PVEA 4B8CD 5MFZA 1JYBA 2XJRA 1IW7D 3RYGA 1RWDA 1S30A 4V196
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2V0E A;  2CKA A;  2V0F A;  2CKC A; 
#chains in the Genus database with same CATH topology
 3PL5 A;  2HR5 A;  3PKJ A;  3LWV B;  4A93 L;  1R9T L;  1BFY A;  1BQ9 A;  3H9C A;  4A3G L;  2QL0 A;  1RDG A;  3HOX L;  3P2A A;  2PVX A;  2Y0S P;  4ME3 A;  2ERJ A;  4QIW P;  2M4V A;  3QQC E;  4A3J L;  4C2M 1;  2YU9 L;  1CAD A;  2CKC A;  3H97 A;  2J9U B;  3B0A B;  2VL6 A;  5MF6 A;  1BE7 A;  1YK5 A;  6RXN A;  5H1S c;  2MS3 A;  3PKI A;  3RZT A;  5GAH c;  5GAE c;  4K9F A;  2APO B;  2AQC A;  4G6B A;  1LKM A;  1H7V A;  3S2H L;  3HAX C;  3MQK B;  1PFW A;  4JAG A;  1RB9 A;  4A3C L;  3S1R L;  2JI3 A;  4WFN 1;  3KYY A;  4BXX L;  4ZN3 B;  5M5W L;  3FDJ A;  1Y1W L;  2CKA A;  1R0F A;  3HOZ L;  3FKI L;  1PZX A;  5DM7 1;  3GTP L;  3M4O L;  1F4L A;  4A3I L;  3HOY L;  1NXE A;  5K2M E;  2NVY L;  1PFY A;  5AN9 H;  3GTO L;  2A69 D;  3M3Y L;  1B13 A;  2VUM L;  3PIO 1;  4XXB B;  4POF A;  4LHN A;  1RWD A;  4V19 6;  5C44 L;  1B2J A;  3I4N L;  2JA7 L;  5M5X L;  2AYJ A;  2O5J D;  1TWC L;  3HOV L;  5JVH 1;  1Z92 B;  2XJT A;  4GS7 D;  3S1Q L;  3MPS A;  1OWB A;  5MLC 3;  1T9Q A;  2NVT L;  5IYC L;  2Z3Q B;  1RYT A;  5IY0 A;  5IYB L;  5GAD c;  5MGN A;  4A3M L;  2BE5 D;  3LWP B;  7RXN A;  3S16 L;  2XJS A;  5EIO C;  3ZG6 A;  3SS2 A;  3NFP I;  5AI3 A;  4BBR L;  3PZA A;  3QVD A;  3S14 L;  3KYW A;  4AR3 A;  2NVX L;  2NVQ L;  3VPB E;  1RDV A;  1SFO L;  2GMG A;  8RXN A;  5M5Y L;  1CAA A;  1T9O A;  4A3F L;  1DVB A;  2HVY C;  3GTM L;  4Y52 L;  1IU5 A;  3KYX A;  3J7Z 1;  3K7A L;  1LKP A;  2JI2 A;  1LTL A;  1I50 L;  5GAG c;  3LPE B;  1ODH A;  3KYV A;  2PMZ P;  1ZRP A;  5FJ8 L;  2ZIX A;  2E2J L;  3S17 L;  4E6Y A;  2B5I D;  3GTL L;  1TWH L;  2B63 L;  2A68 D;  1VZH A;  3HJY B;  3RZO L;  4AI2 A;  4ZN1 B;  3IU3 I;  4BBS L;  3WWN B;  1PFU A;  3MSU A;  2RDV A;  1R0H A;  2KN9 A;  2V3B B;  2XJQ A;  1VZI A;  4AI1 A;  2PVE A;  5MFZ A;  1TWA L;  5C4X L;  5C3E L;  5MFP A;  3P8B A;  4AI3 A;  1BRF A;  2EY4 E;  5C4J L;  1R0I A;  4X6A L;  1VCX A;  1OWC A;  3PWF A;  3GTJ L;  5IYD L;  5FLM L;  2L0Z A;  3WWL A;  2ERS A;  3K35 A;  1YUX A;  4AR4 A;  1QYB A;  2A6E D;  2AUS B;  4BY7 L;  2XJP A;  2RFK B;  1I6H L;  3KYU A;  4JAD A;  5M3M L;  1E8J A;  4TPU A;  3S2D L;  4A3L L;  2H12 A;  3HKZ P;  4LHL A;  2C6B A;  1DX8 A;  2V0F A;  5DM6 1;  1LKO A;  4TVM A;  1WJV A;  2XJV A;  2Z3R B;  4XGH A;  2M6P A;  1NXG A;  4A3D L;  1SMM A;  1FHH A;  3HOU L;  1B2O A;  3B08 B;  2PPT A;  3LWR B;  3LNL A;  1PFV A;  1SMU A;  4YWM A;  2KKD A;  1S2Z A;  4AHX A;  3LWO B;  3S1M L;  2V0E A;  2PYA A;  3I4M L;  1IRO A;  2JA5 L;  4U67 1;  2JA6 L;  3PIP 1;  1FHM A;  3A44 A;  2E2I L;  4Y7N L;  2R93 L;  4AYB P;  1WCM L;  2C6A A;  1YV1 A;  1R0J A;  4A3B L;  4JAF A;  3J7Y 1;  2XJR A;  1IW7 D;  1I3Q L;  5IP9 L;  1C09 A;  4C3H L;  3PO2 L;  2PSM C;  4AI0 A;  1S24 A;  4AR6 A;  1BQ8 A;  2K2D A;  1Y1V L;  1TWG L;  2WAQ P;  3GTK L;  1VZG A;  3JR7 A;  2E2H L;  2DSX A;  3RZ6 A;  1QQT A;  4RXN A;  3H0G L;  4C3J L;  3GTQ L;  4JAE A;  1QCV A;  5JVG 1;  2M6O A;  3HOW L;  2M4Y A;  4AHW A;  3H99 A;  4AHY A;  2R7Z L;  4POG A;  1IRN A;  2CR8 A;  1YUZ A;  5IP7 L;  2A6H D;  1SMW A;  1K83 L;  1R0G A;  5AI2 A;  5M3F L;  3S1N L;  2R92 L;  2LCQ A;  4A3K L;  1B71 A;  3H9B A;  4BY1 L;  1T9P A;  1P7P A;  1NNQ A;  1IU6 A;  4AR5 A;  2XJU A;  3LWQ B;  4AHZ A;  3RZD L;  3S15 L;  5EIN C;  2JI1 A;  2NYD A;  4C3I L;  1YK4 A;  2JA8 L;  4UY8 1;  1RYQ A;  4YWL A;  4A3E L;  3GTG L;  3H3V M;  2WB1 P;  1TWF L;  3HJW B;  3PO3 L;  5RXN A;  4B8C D;  1JYB A;  3RYG A;  3CQZ L;  1S30 A; 
#chains in the Genus database with same CATH homology
 5MFP A;  1C09 A;  3P8B A;  4AI3 A;  2HR5 A;  1BRF A;  1B2J A;  2PSM C;  1R0I A;  3PKJ A;  4AI0 A;  1VCX A;  1OWC A;  1S24 A;  3PWF A;  1BFY A;  1BQ9 A;  2L0Z A;  4AR6 A;  3WWL A;  2ERS A;  1BQ8 A;  3K35 A;  2K2D A;  1YUX A;  4AR4 A;  2QL0 A;  1QYB A;  2AYJ A;  2O5J D;  1RDG A;  2A6E D;  1VZG A;  3P2A A;  5JVH 1;  1Z92 B;  2PVX A;  4ME3 A;  2ERJ A;  2XJP A;  2M4V A;  2XJT A;  3QQC E;  4GS7 D;  3MPS A;  1OWB A;  5MLC 3;  1T9Q A;  3KYU A;  2CKC A;  1CAD A;  2DSX A;  3RZ6 A;  2J9U B;  3B0A B;  4JAD A;  2VL6 A;  5MF6 A;  1BE7 A;  4RXN A;  1YK5 A;  2Z3Q B;  1RYT A;  4TPU A;  6RXN A;  1E8J A;  5IY0 A;  4JAE A;  1QCV A;  5H1S c;  5GAD c;  5MGN A;  2MS3 A;  3PKI A;  5JVG 1;  2BE5 D;  2H12 A;  2M6O A;  3RZT A;  2M4Y A;  7RXN A;  5GAH c;  5GAE c;  2XJS A;  4LHL A;  4AHW A;  2C6B A;  4AHY A;  4K9F A;  5EIO C;  4POG A;  1DX8 A;  2V0F A;  3ZG6 A;  5DM6 1;  1IRN A;  1LKO A;  4TVM A;  2CR8 A;  1WJV A;  4G6B A;  3SS2 A;  3NFP I;  5AI3 A;  1LKM A;  1YUZ A;  2XJV A;  1H7V A;  2Z3R B;  4XGH A;  2M6P A;  3PZA A;  2A6H D;  1NXG A;  1SMW A;  3QVD A;  3KYW A;  4AR3 A;  1R0G A;  1SMM A;  1FHH A;  5AI2 A;  3VPB E;  1B2O A;  2LCQ A;  1RDV A;  4JAG A;  1RB9 A;  2GMG A;  3B08 B;  8RXN A;  2PPT A;  2JI3 A;  1B71 A;  4WFN 1;  1T9P A;  1CAA A;  1T9O A;  3KYY A;  1DVB A;  3LNL A;  1SMU A;  4ZN3 B;  1IU5 A;  3KYX A;  4YWM A;  3J7Z 1;  1LKP A;  2KKD A;  1NNQ A;  1S2Z A;  2CKA A;  1IU6 A;  2JI2 A;  4AHX A;  4AR5 A;  1LTL A;  2XJU A;  1R0F A;  5GAG c;  3LPE B;  2V0E A;  2PYA A;  4AHZ A;  3KYV A;  5DM7 1;  1ODH A;  5EIN C;  1ZRP A;  1IRO A;  2JI1 A;  2NYD A;  2ZIX A;  4U67 1;  3PIP 1;  1FHM A;  3A44 A;  1YK4 A;  4E6Y A;  2B5I D;  1NXE A;  1VZH A;  2A68 D;  5K2M E;  4AI2 A;  2C6A A;  3IU3 I;  1RYQ A;  4ZN1 B;  4UY8 1;  1YV1 A;  3WWN B;  4YWL A;  5AN9 H;  2A69 D;  3MSU A;  2RDV A;  1R0H A;  1B13 A;  1R0J A;  2KN9 A;  3PIO 1;  2V3B B;  4JAF A;  2XJQ A;  1VZI A;  4XXB B;  4AI1 A;  3J7Y 1;  4POF A;  4LHN A;  5RXN A;  2PVE A;  4B8C D;  5MFZ A;  1JYB A;  2XJR A;  1IW7 D;  3RYG A;  1RWD A;  1S30 A;  4V19 6; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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