2CSCA

Structure of ternary complexes of citrate synthase with d-and l-malate: mechanistic implications
Total Genus 149
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
149
sequence length
433
structure length
429
Chain Sequence
ASSTNLKDVLAALIPKEQARIKTFRQQHGGTALGQITVDMSYGGMRGMKGLVYETSVLDPDEGIRFRGFSIPECQKLLPKGGGGEPLPEGLFWLLVTGQIPTGAQVSWLSKEWAKRAALPSHVVTMLDNFPTNLHPMSQLSAAITALNSESNFARAYAEGILRTKYWEMVYESAMDLIAKLPCVAAKIYRNLYRAGSSIGAIDSKLDWSHNFTNMLGYTDAQFTELMRLYLTIHSDHEGGNVSAHTSHLVGSALSDPYLSFAAAMNGLAGPLHGLANQEVLGWLAQLQKAAGADASLRDYIWNTLNSGRVVPGYGHAVLRKTDPRYTCQREFALKHLPGDPMFKLVAQLYKIVPNVLLEQGAAANPWPNVDAHSGVLLQYYGMTEMNYYTVLFGVSRALGVLAQLIWSRALGFPLERPKSMSTDGLIAL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title 1.9-A structures of ternary complexes of citrate synthase with D- and L-malate: mechanistic implications.
pubmed doi rcsb
molecule tags Lyase
source organism Gallus gallus
molecule keywords CITRATE SYNTHASE
total genus 149
structure length 429
sequence length 433
ec nomenclature ec 2.3.3.1: Citrate (Si)-synthase.
pdb deposition date 1990-05-07

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00285 Citrate_synt Citrate synthase, C-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.230.10 Mainly Alpha Orthogonal Bundle Cytochrome p450-Terp; domain 2 Cytochrome P450-Terp, domain 2 2cscA02
1.10.580.10 Mainly Alpha Orthogonal Bundle Citrate Synthase; domain 1 Citrate Synthase, domain 1 2cscA01
1VGPA 5CTSA 3CSCA 6CSCA 4YBOA 5CSCB 1OWBA 2P2WA 1NXGA 1CSRA 4CSCA 4XGHA 4E6YA 3O8JA 1IXEA 1O7XA 2R9EA 4JAFA 4JAGA 1AMZA 1IOMA 4CTSA 1CSCA 2C6XA 2H12A 2CTSA 6CTSA 4JAEA 1VGMA 3HWKA 1A59A 1NXEA 1AJ8A 3ENJA 1CSIA 1CTSA 1CSHA 2IBPA 1OWCA 4TVMA 3TQGA 1AL6A 1CSSA 2IFCA 3MSUA 4G6BA 2R26A 2CSCA 4JADA 5CSCA
chains in the Genus database with same CATH superfamily
1VGPA 5CTSA 3CSCA 6CSCA 4YBOA 5CSCB 1OWBA 2P2WA 1NXGA 1CSRA 4XGHA 4CSCA 4E6YA 3O8JA 1IXEA 1O7XA 2R9EA 4JAFA 4JAGA 1AMZA 1IOMA 4CTSA 1CSCA 2C6XA 2H12A 2CTSA 6CTSA 4JAEA 1VGMA 3HWKA 1A59A 1NXEA 1AJ8A 3ENJA 1CSIA 1CTSA 1CSHA 2IBPA 1OWCA 4TVMA 3TQGA 1AL6A 1CSSA 2IFCA 3MSUA 4G6BA 2R26A 2CSCA 4JADA 5CSCA
chains in the Genus database with same CATH topology
1VGPA 5CTSA 3CSCA 6CSCA 4YBOA 5CSCB 1OWBA 2P2WA 1NXGA 1CSRA 4CSCA 4XGHA 4E6YA 3O8JA 1IXEA 1O7XA 2R9EA 4JAFA 4JAGA 1AMZA 1IOMA 4CTSA 1CSCA 2C6XA 2H12A 2CTSA 6CTSA 4JAEA 1VGMA 3HWKA 1A59A 1NXEA 1AJ8A 3ENJA 1CSIA 1CTSA 1CSHA 2IBPA 1OWCA 4TVMA 3TQGA 1AL6A 1CSSA 2IFCA 3MSUA 4G6BA 2R26A 2CSCA 4JADA 5CSCA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1VGP A;  5CTS A;  3CSC A;  6CSC A;  4YBO A;  5CSC B;  1OWB A;  2P2W A;  1NXG A;  1CSR A;  4CSC A;  4XGH A;  4E6Y A;  3O8J A;  1IXE A;  1O7X A;  2R9E A;  4JAF A;  4JAG A;  1AMZ A;  1IOM A;  4CTS A;  1CSC A;  2C6X A;  2H12 A;  2CTS A;  6CTS A;  4JAE A;  1VGM A;  3HWK A;  1A59 A;  1NXE A;  1AJ8 A;  3ENJ A;  1CSI A;  1CTS A;  1CSH A;  2IBP A;  1OWC A;  4TVM A;  3TQG A;  1AL6 A;  1CSS A;  2IFC A;  3MSU A;  4G6B A;  2R26 A;  2CSC A;  4JAD A;  5CSC A; 
#chains in the Genus database with same CATH topology
 1VGP A;  5CTS A;  3CSC A;  6CSC A;  4YBO A;  5CSC B;  1OWB A;  2P2W A;  1NXG A;  1CSR A;  4XGH A;  4CSC A;  4E6Y A;  3O8J A;  1IXE A;  1O7X A;  2R9E A;  4JAF A;  4JAG A;  1AMZ A;  1IOM A;  4CTS A;  1CSC A;  2C6X A;  2H12 A;  2CTS A;  6CTS A;  4JAE A;  1VGM A;  3HWK A;  1A59 A;  1NXE A;  1AJ8 A;  3ENJ A;  1CSI A;  1CTS A;  1CSH A;  2IBP A;  1OWC A;  4TVM A;  3TQG A;  1AL6 A;  1CSS A;  2IFC A;  3MSU A;  4G6B A;  2R26 A;  2CSC A;  4JAD A;  5CSC A; 
#chains in the Genus database with same CATH homology
 1VGP A;  5CTS A;  3CSC A;  6CSC A;  4YBO A;  5CSC B;  1OWB A;  2P2W A;  1NXG A;  1CSR A;  4CSC A;  4XGH A;  4E6Y A;  3O8J A;  1IXE A;  1O7X A;  2R9E A;  4JAF A;  4JAG A;  1AMZ A;  1IOM A;  4CTS A;  1CSC A;  2C6X A;  2H12 A;  2CTS A;  6CTS A;  4JAE A;  1VGM A;  3HWK A;  1A59 A;  1NXE A;  1AJ8 A;  3ENJ A;  1CSI A;  1CTS A;  1CSH A;  2IBP A;  1OWC A;  4TVM A;  3TQG A;  1AL6 A;  1CSS A;  2IFC A;  3MSU A;  4G6B A;  2R26 A;  2CSC A;  4JAD A;  5CSC A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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