2CTXA

The refined crystal structure of alpha-cobratoxin from naja naja siamensis at 2.4-angstroms resolution
Total Genus 11
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
11
sequence length
71
structure length
71
Chain Sequence
IRCFITPDITSKDCPNGHVCYTKTWCDAFCSIRGKRVDLGCAATCPTVKTGVDIQCCSTDNCNPFPTRKRP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The refined crystal structure of alpha-cobratoxin from Naja naja siamensis at 2.4-A resolution.
pubmed rcsb
molecule tags Neurotoxin
source organism Naja naja
molecule keywords ALPHA-COBRATOXIN
total genus 11
structure length 71
sequence length 71
ec nomenclature
pdb deposition date 1991-09-24

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00087 Toxin_TOLIP Snake toxin and toxin-like protein
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.10.60.10 Mainly Beta Ribbon CD59 CD59 2ctxA00
6EBXA 1HC9A 2H8UA 4LFTA 1LSIA 2BTXA 1YWHA 1QKDA 4UY2C 2ERAA 3BT2U 1ERAA 3KFDI 4ZQYA 1TXBA 1HAAA 1ERGA 1IDGA 2NBTA 1CXOA 1LJZA 2MUOA 2PJYB 2CRTA 1CRFA 1TGXA 1CVOA 2I9BE 1RGJA 1NTXA 4HQPF 1CREA 2QJAC 3KFDE 1B41B 4BDTB 2MJ4A 3PLCA 1IDHA 1W6BA 1F8UB 3U73U 2PJYC 1LXHA 1V6PA 4P7UA 2FD6U 1ABTA 2H64B 2H62D 2CDXA 2J8BA 2MJ0A 5IMYC 2LA1A 2UX2A 3HH7A 1QKEA 2BHIA 1CXNA 4DO8A 1KXIA 2GOOB 4IYEA 1DRSA 5DZ5A 3U74U 4BIKB 4FAOC 1FFJA 2H64C 5EBXA 3FEVA 3QB4B 4RUDA 1VB0A 2GOOC 1M9ZA 1HOYA 1IQ9A 1KBTA 1CTXA 2MHYA 1HC9B 1G6MA 1KBAA 1LXGA 1IDIA 2N99A 1CDQA 3NH7A 1NXBA 1PLOA 2QC1A 1HAJA 1REWC 2L03A 1CDRA 1CDTA 2JQPA 1NORA 4AEAA 1ES7B 5DO6A 1MR6A 1JBDA 2H7ZA 1TXAA 2CTXA 1KFHA 1L4WA 1QM7A 1NTNA 1TFSA 1LX5B 1ONJA 2VLWA 1COEA 2K3GA 1CODA 1BTEA 1XT3A 1JE9A 2HLRA 2UWRA 1NYUA 1KS6A 2MFAA 2X8BB 4OM5A 5IMTD 1FASA 1S4YA 3VTSA 1F94A 2CRSA 4OM4A 4QTIU 3EBXA 1RL5A 1FF4A 4FAOE 3EVSC 1FSCA 1KC4A 3ERAA 2H62C 1NEAA 1CHVS 4EY8B 1IK8A 1IDLA 2H5FA 2OFSA 3LAQU 2L5SA 2LCRA 1ZADA 1KBSA 1IJCA 1H0JA 3NDSA 1CDSA 2H7ZB 1CCQA 1KU6B 1NYSA 1CB9A 1I02A 2ABXA 1UG4A 1IKCA 2JVEA 2MJYA 1BXPA 1JGKA 2QJBC 1MAHF 4XJJA 2QJ9C 5DU1A 1FSSB 1FRAA 1KTZB 2CCXA 3NEQA 2MUPA 2HLQA 1KL8A 3BT1U
chains in the Genus database with same CATH superfamily
6EBXA 1HC9A 2H8UA 4LFTA 1LSIA 2BTXA 1YWHA 1QKDA 4UY2C 2ERAA 3BT2U 1ERAA 3KFDI 4ZQYA 1TXBA 1HAAA 1ERGA 1IDGA 2NBTA 1CXOA 1LJZA 2MUOA 2PJYB 2CRTA 1CRFA 1TGXA 1CVOA 2I9BE 1RGJA 1NTXA 4HQPF 1CREA 2QJAC 3KFDE 1B41B 4BDTB 2MJ4A 3PLCA 1IDHA 1W6BA 1F8UB 3U73U 2PJYC 1LXHA 1V6PA 4P7UA 2FD6U 1ABTA 2H64B 2H62D 2CDXA 2J8BA 2MJ0A 5IMYC 2LA1A 2UX2A 3HH7A 1QKEA 2BHIA 1CXNA 4DO8A 1KXIA 2GOOB 4IYEA 1DRSA 5DZ5A 3U74U 4BIKB 4FAOC 4KSNA 1FFJA 2H64C 5EBXA 3FEVA 3QB4B 4RUDA 1VB0A 2GOOC 1M9ZA 1HOYA 1IQ9A 1KBTA 1CTXA 2MHYA 1HC9B 1G6MA 1KBAA 1LXGA 1IDIA 2N99A 1CDQA 3NH7A 1NXBA 1PLOA 2QC1A 1HAJA 1REWC 2L03A 1CDRA 1CDTA 2JQPA 1NORA 4AEAA 1ES7B 5DO6A 1MR6A 1JBDA 2H7ZA 1TXAA 2CTXA 1KFHA 1L4WA 1QM7A 1NTNA 1TFSA 1LX5B 1ONJA 2VLWA 1COEA 2K3GA 1CODA 1BTEA 1XT3A 1JE9A 2HLRA 2UWRA 1NYUA 1KS6A 2MFAA 2X8BB 4OM5A 5IMTD 1FASA 1S4YA 3VTSA 1F94A 2CRSA 4OM4A 4QTIU 3EBXA 1RL5A 1FF4A 4FAOE 3EVSC 1FSCA 1KC4A 3ERAA 2H62C 1NEAA 1CHVS 4EY8B 1IK8A 1IDLA 2H5FA 2OFSA 3LAQU 2L5SA 2LCRA 1ZADA 1KBSA 1IJCA 1H0JA 3NDSA 1CDSA 2H7ZB 1CCQA 1KU6B 1NYSA 1CB9A 1I02A 2ABXA 1UG4A 1IKCA 2JVEA 2MJYA 1BXPA 1JGKA 2QJBC 1MAHF 4XJJA 2QJ9C 5DU1A 1FSSB 1FRAA 1KTZB 2CCXA 3NEQA 2MUPA 2HLQA 1KL8A 3BT1U
chains in the Genus database with same CATH topology
6EBXA 1HC9A 2H8UA 4LFTA 1LSIA 2BTXA 1YWHA 1QKDA 4UY2C 2ERAA 3BT2U 1ERAA 3KFDI 4ZQYA 1TXBA 1HAAA 1ERGA 1IDGA 2NBTA 1CXOA 1LJZA 2MUOA 2PJYB 2CRTA 1CRFA 1TGXA 1CVOA 2I9BE 1RGJA 1NTXA 4HQPF 1CREA 2QJAC 3KFDE 1B41B 4BDTB 2MJ4A 3PLCA 1IDHA 1W6BA 1F8UB 3U73U 2PJYC 1LXHA 1V6PA 4P7UA 2FD6U 1ABTA 2H64B 2H62D 2CDXA 2J8BA 2MJ0A 5IMYC 2LA1A 2UX2A 3HH7A 1QKEA 2BHIA 1CXNA 4DO8A 1KXIA 2GOOB 4IYEA 1DRSA 5DZ5A 3U74U 4BIKB 4FAOC 4KSNA 1FFJA 2H64C 5EBXA 3FEVA 3QB4B 4RUDA 1VB0A 2GOOC 1M9ZA 1HOYA 1IQ9A 1KBTA 1CTXA 2MHYA 1HC9B 1G6MA 1KBAA 1LXGA 1IDIA 2N99A 1CDQA 3NH7A 1NXBA 1PLOA 2QC1A 1HAJA 1REWC 2L03A 1CDRA 1CDTA 2JQPA 1NORA 4AEAA 1ES7B 5DO6A 1MR6A 1JBDA 2H7ZA 1TXAA 2CTXA 1KFHA 1L4WA 1QM7A 1NTNA 1TFSA 1LX5B 1ONJA 2VLWA 1COEA 2K3GA 1CODA 1BTEA 1XT3A 1JE9A 2HLRA 2UWRA 1NYUA 1KS6A 2MFAA 2X8BB 4OM5A 5IMTD 1FASA 1S4YA 3VTSA 1F94A 2CRSA 4OM4A 4QTIU 3EBXA 1RL5A 1FF4A 4FAOE 3EVSC 1FSCA 1KC4A 3ERAA 2H62C 1NEAA 1CHVS 4EY8B 1IK8A 1IDLA 2H5FA 2OFSA 3LAQU 2L5SA 2LCRA 1ZADA 1KBSA 1IJCA 1H0JA 3NDSA 1CDSA 2H7ZB 1CCQA 1KU6B 1NYSA 1CB9A 1I02A 2ABXA 1UG4A 1IKCA 2JVEA 2MJYA 1BXPA 1JGKA 2QJBC 1MAHF 4XJJA 2QJ9C 5DU1A 1FSSB 1FRAA 1KTZB 2CCXA 3NEQA 2MUPA 2HLQA 1KL8A 3BT1U
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 6EBX A;  1HC9 A;  2H8U A;  4LFT A;  1LSI A;  2BTX A;  1YWH A;  1QKD A;  4UY2 C;  2ERA A;  3BT2 U;  1ERA A;  3KFD I;  4ZQY A;  1TXB A;  1HAA A;  1ERG A;  1IDG A;  2NBT A;  1CXO A;  1LJZ A;  2MUO A;  2PJY B;  2CRT A;  1CRF A;  1TGX A;  1CVO A;  2I9B E;  1RGJ A;  1NTX A;  4HQP F;  1CRE A;  2QJA C;  3KFD E;  1B41 B;  4BDT B;  2MJ4 A;  3PLC A;  1IDH A;  1W6B A;  1F8U B;  3U73 U;  2PJY C;  1LXH A;  1V6P A;  4P7U A;  2FD6 U;  1ABT A;  2H64 B;  2H62 D;  2CDX A;  2J8B A;  2MJ0 A;  5IMY C;  2LA1 A;  2UX2 A;  3HH7 A;  1QKE A;  2BHI A;  1CXN A;  4DO8 A;  1KXI A;  2GOO B;  4IYE A;  1DRS A;  5DZ5 A;  3U74 U;  4BIK B;  4FAO C;  1FFJ A;  2H64 C;  5EBX A;  3FEV A;  3QB4 B;  4RUD A;  1VB0 A;  2GOO C;  1M9Z A;  1HOY A;  1IQ9 A;  1KBT A;  1CTX A;  2MHY A;  1HC9 B;  1G6M A;  1KBA A;  1LXG A;  1IDI A;  2N99 A;  1CDQ A;  3NH7 A;  1NXB A;  1PLO A;  2QC1 A;  1HAJ A;  1REW C;  2L03 A;  1CDR A;  1CDT A;  2JQP A;  1NOR A;  4AEA A;  1ES7 B;  5DO6 A;  1MR6 A;  1JBD A;  2H7Z A;  1TXA A;  2CTX A;  1KFH A;  1L4W A;  1QM7 A;  1NTN A;  1TFS A;  1LX5 B;  1ONJ A;  2VLW A;  1COE A;  2K3G A;  1COD A;  1BTE A;  1XT3 A;  1JE9 A;  2HLR A;  2UWR A;  1NYU A;  1KS6 A;  2MFA A;  2X8B B;  4OM5 A;  5IMT D;  1FAS A;  1S4Y A;  3VTS A;  1F94 A;  2CRS A;  4OM4 A;  4QTI U;  3EBX A;  1RL5 A;  1FF4 A;  4FAO E;  3EVS C;  1FSC A;  1KC4 A;  3ERA A;  2H62 C;  1NEA A;  1CHV S;  4EY8 B;  1IK8 A;  1IDL A;  2H5F A;  2OFS A;  3LAQ U;  2L5S A;  2LCR A;  1ZAD A;  1KBS A;  1IJC A;  1H0J A;  3NDS A;  1CDS A;  2H7Z B;  1CCQ A;  1KU6 B;  1NYS A;  1CB9 A;  1I02 A;  2ABX A;  1UG4 A;  1IKC A;  2JVE A;  2MJY A;  1BXP A;  1JGK A;  2QJB C;  1MAH F;  4XJJ A;  2QJ9 C;  5DU1 A;  1FSS B;  1FRA A;  1KTZ B;  2CCX A;  3NEQ A;  2MUP A;  2HLQ A;  1KL8 A;  3BT1 U; 
#chains in the Genus database with same CATH topology
 6EBX A;  1HC9 A;  2H8U A;  4LFT A;  1LSI A;  2BTX A;  1YWH A;  1QKD A;  4UY2 C;  2ERA A;  3BT2 U;  1ERA A;  3KFD I;  4ZQY A;  1TXB A;  1HAA A;  1ERG A;  1IDG A;  2NBT A;  1CXO A;  1LJZ A;  2MUO A;  2PJY B;  2CRT A;  1CRF A;  1TGX A;  1CVO A;  2I9B E;  1RGJ A;  1NTX A;  4HQP F;  1CRE A;  2QJA C;  3KFD E;  1B41 B;  4BDT B;  2MJ4 A;  3PLC A;  1IDH A;  1W6B A;  1F8U B;  3U73 U;  2PJY C;  1LXH A;  1V6P A;  4P7U A;  2FD6 U;  1ABT A;  2H64 B;  2H62 D;  2CDX A;  2J8B A;  2MJ0 A;  5IMY C;  2LA1 A;  2UX2 A;  3HH7 A;  1QKE A;  2BHI A;  1CXN A;  4DO8 A;  1KXI A;  2GOO B;  4IYE A;  1DRS A;  5DZ5 A;  3U74 U;  4BIK B;  4FAO C;  4KSN A;  1FFJ A;  2H64 C;  5EBX A;  3FEV A;  3QB4 B;  4RUD A;  1VB0 A;  2GOO C;  1M9Z A;  1HOY A;  1IQ9 A;  1KBT A;  1CTX A;  2MHY A;  1HC9 B;  1G6M A;  1KBA A;  1LXG A;  1IDI A;  2N99 A;  1CDQ A;  3NH7 A;  1NXB A;  1PLO A;  2QC1 A;  1HAJ A;  1REW C;  2L03 A;  1CDR A;  1CDT A;  2JQP A;  1NOR A;  4AEA A;  1ES7 B;  5DO6 A;  1MR6 A;  1JBD A;  2H7Z A;  1TXA A;  2CTX A;  1KFH A;  1L4W A;  1QM7 A;  1NTN A;  1TFS A;  1LX5 B;  1ONJ A;  2VLW A;  1COE A;  2K3G A;  1COD A;  1BTE A;  1XT3 A;  1JE9 A;  2HLR A;  2UWR A;  1NYU A;  1KS6 A;  2MFA A;  2X8B B;  4OM5 A;  5IMT D;  1FAS A;  1S4Y A;  3VTS A;  1F94 A;  2CRS A;  4OM4 A;  4QTI U;  3EBX A;  1RL5 A;  1FF4 A;  4FAO E;  3EVS C;  1FSC A;  1KC4 A;  3ERA A;  2H62 C;  1NEA A;  1CHV S;  4EY8 B;  1IK8 A;  1IDL A;  2H5F A;  2OFS A;  3LAQ U;  2L5S A;  2LCR A;  1ZAD A;  1KBS A;  1IJC A;  1H0J A;  3NDS A;  1CDS A;  2H7Z B;  1CCQ A;  1KU6 B;  1NYS A;  1CB9 A;  1I02 A;  2ABX A;  1UG4 A;  1IKC A;  2JVE A;  2MJY A;  1BXP A;  1JGK A;  2QJB C;  1MAH F;  4XJJ A;  2QJ9 C;  5DU1 A;  1FSS B;  1FRA A;  1KTZ B;  2CCX A;  3NEQ A;  2MUP A;  2HLQ A;  1KL8 A;  3BT1 U; 
#chains in the Genus database with same CATH homology
 6EBX A;  1HC9 A;  2H8U A;  4LFT A;  1LSI A;  2BTX A;  1YWH A;  1QKD A;  4UY2 C;  2ERA A;  3BT2 U;  1ERA A;  3KFD I;  4ZQY A;  1TXB A;  1HAA A;  1ERG A;  1IDG A;  2NBT A;  1CXO A;  1LJZ A;  2MUO A;  2PJY B;  2CRT A;  1CRF A;  1TGX A;  1CVO A;  2I9B E;  1RGJ A;  1NTX A;  4HQP F;  1CRE A;  2QJA C;  3KFD E;  1B41 B;  4BDT B;  2MJ4 A;  3PLC A;  1IDH A;  1W6B A;  1F8U B;  3U73 U;  2PJY C;  1LXH A;  1V6P A;  4P7U A;  2FD6 U;  1ABT A;  2H64 B;  2H62 D;  2CDX A;  2J8B A;  2MJ0 A;  5IMY C;  2LA1 A;  2UX2 A;  3HH7 A;  1QKE A;  2BHI A;  1CXN A;  4DO8 A;  1KXI A;  2GOO B;  4IYE A;  1DRS A;  5DZ5 A;  3U74 U;  4BIK B;  4FAO C;  4KSN A;  1FFJ A;  2H64 C;  5EBX A;  3FEV A;  3QB4 B;  4RUD A;  1VB0 A;  2GOO C;  1M9Z A;  1HOY A;  1IQ9 A;  1KBT A;  1CTX A;  2MHY A;  1HC9 B;  1G6M A;  1KBA A;  1LXG A;  1IDI A;  2N99 A;  1CDQ A;  3NH7 A;  1NXB A;  1PLO A;  2QC1 A;  1HAJ A;  1REW C;  2L03 A;  1CDR A;  1CDT A;  2JQP A;  1NOR A;  4AEA A;  1ES7 B;  5DO6 A;  1MR6 A;  1JBD A;  2H7Z A;  1TXA A;  2CTX A;  1KFH A;  1L4W A;  1QM7 A;  1NTN A;  1TFS A;  1LX5 B;  1ONJ A;  2VLW A;  1COE A;  2K3G A;  1COD A;  1BTE A;  1XT3 A;  1JE9 A;  2HLR A;  2UWR A;  1NYU A;  1KS6 A;  2MFA A;  2X8B B;  4OM5 A;  5IMT D;  1FAS A;  1S4Y A;  3VTS A;  1F94 A;  2CRS A;  4OM4 A;  4QTI U;  3EBX A;  1RL5 A;  1FF4 A;  4FAO E;  3EVS C;  1FSC A;  1KC4 A;  3ERA A;  2H62 C;  1NEA A;  1CHV S;  4EY8 B;  1IK8 A;  1IDL A;  2H5F A;  2OFS A;  3LAQ U;  2L5S A;  2LCR A;  1ZAD A;  1KBS A;  1IJC A;  1H0J A;  3NDS A;  1CDS A;  2H7Z B;  1CCQ A;  1KU6 B;  1NYS A;  1CB9 A;  1I02 A;  2ABX A;  1UG4 A;  1IKC A;  2JVE A;  2MJY A;  1BXP A;  1JGK A;  2QJB C;  1MAH F;  4XJJ A;  2QJ9 C;  5DU1 A;  1FSS B;  1FRA A;  1KTZ B;  2CCX A;  3NEQ A;  2MUP A;  2HLQ A;  1KL8 A;  3BT1 U; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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