2D0KA

Methionine-free mutant of escherichia coli dihydrofolate reductase
Total Genus 41
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
41
sequence length
159
structure length
159
Chain Sequence
AISLIAALAVDRVIGNENALPWNLPADLAWFKRNTLNKPVIYGRHTWESIGRPLPGRKNIILSSQPGTDDRVTWVKSVDEAIAAAGDVPEIFVIGGGRVYEQFLPKAQKLYLTHIDAEVEGDTHFPDYEPDDWESVFSEFHDADAQNSHSYSFEILERR
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Evolutional Design of a Hyperactive Cysteine- and Methionine-free Mutant of Escherichia coli Dihydrofolate Reductase
pubmed doi rcsb
molecule keywords Dihydrofolate reductase
molecule tags Oxidoreductase
source organism Escherichia coli
total genus 41
structure length 159
sequence length 159
chains with identical sequence B
ec nomenclature ec 1.5.1.3: Dihydrofolate reductase.
pdb deposition date 2005-08-04

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00186 DHFR_1 Dihydrofolate reductase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.430.10 Alpha Beta 3-Layer(aba) Sandwich Dihydrofolate Reductase, subunit A Dihydrofolate Reductase, subunit A 2d0kA00
2BL9A 3EEKA 1DR1A 3UM5A 4ELFA 3CL9A 1RA8A 3GI2A 1CZ3A 3M08A 1AI9A 3F0SX 3RG9A 3TQBA 3K47A 2FZHA 1DHJA 2ITHA 3KFYA 4IXFX 3DGAA 4P3RA 1MVSA 4XE6X 1BZFA 3FYWX 3F8YA 4LAEX 3NZ6X 1ZDRA 3ZPGA 1D1GA 3NZBX 3GYFA 1JUVA 1VJ3A 2QK8A 3DL6A 7DFRA 1AOEA 2W3VA 3OCHA 4PTJA 1RF7A 5E8QA 3Q1HA 2FZJA 3JWFA 3SGYA 3ROAA 3CD2A 3EIGA 5ECXA 1U71A 4XRBA 4GH8A 5HUIA 1YHOA 4KAKA 3NZDA 5DXVA 2CD2A 3VCOA 1PDBA 3IRNA 1DRHA 4LAGX 4KJKA 4KJJA 3TD8A 5HF0X 4DP3A 3NZAX 3FREX 3N0HA 4P68A 4IXED 2O7PA 1DYJA 4H98A 1IA2A 3FQOA 5HQZA 2OIPA 1DRFA 2INQA 3NTZA 4FHBA 1JOMA 1DR2A 5HI6A 4H97A 2ZZAA 4H95A 4NX7A 2W3WA 2JYBA 3FQ0A 1DG5A 3IROA 4I13A 4QLEA 3NXOA 1DDSA 1M7AA 2C2SA 1PD8A 3HJ3A 3NXXA 3QLYA 1DAJA 5HT5A 2DHFA 4HA9A 1LY4A 4NX6A 1RX6A 1DHFA 1SEJA 2ANOA 4PDJA 1RA1A 3TQAA 3E0BA 5JG0X 3UM6A 1QZFA 3SAIA 1S3UA 3F91A 3OAFA 5HPBA 3EELA 1DISA 3NXVA 3FRFX 4ELHA 1JOLA 5HVBA 1RH3A 5EAJA 1BOZA 4FGHA 4M6LA 3S3VA 4RGCA 8DFRA 1DYIA 3QL3A 5HSRA 3SRWX 4QLGA 4M7UA 3KY8A 2G6VA 3QLWA 4Q0DA 1DIUA 3I3RA 4X5IA 1KMSA 3K74A 4M2XA 3DL5A 5U26A 3TQ8A 3FQCA 3QLXA 2LF1A 4QLFA 1TDRA 2D5NA 3IX9A 3F0BX 2XW7A 4G3MA 4QJCA 4OSGA 2BLAA 5HVEA 4QJZD 3FRDX 3INVA 5FDAA 3FQFA 5ECCA 1DR3A 4Q0EA 2GD9A 1J3KA 4KEBA 2DRCA 4ELBA 3QLRA 2W9TA 3I8AX 1S3VA 2HXVA 3SRUX 3QFXA 1LY3A 1RX2A 3SQYX 3F0VX 1DLRA 1RA2A 4KBNA 4XT8A 3QL0A 5U27A 4IXGX 3L3RA 4FGGA 4X5JA 3SH2A 6DFRA 3FQZA 3KJSA 1DR6A 3FYVX 3R33A 2W3BA 1AO8A 1M79A 3K2HA 4G8ZX 1OHKA 1J3JA 3JW5A 2KGKA 4XT6A 4PSTA 3NXTA 3EX8A 2ANQA 4XECX 4KY4A 1S3YA 4EIZA 3HBBA 3JWKA 2W9HA 3KGYA 3FQVA 4TU5X 3JWCA 4XT7A 3RO9A 2W3MA 1M78A 3SRQX 4HA7A 3IRMA 2P4GA 3D80A 1CD2A 5HF2X 4KLXA 3D84X 2FZIA 1MVTA 3LG4A 3FY9X 4KFJA 4KD7A 2BLBA 4PSSA 3F8ZA 3EEJA 3JSUA 4G95A 3JTWA 3QLZA 2HQPA 3FL8A 4PSYA 1J3IA 2BLCA 1RX7A 4P3QA 1DDRA 2H2QA 1IA4A 4ECKA 3NXYA 4P66A 1OHJA 4XT4A 3GHCA 2W3AA 1RA3A 3QGTA 4OR7A 1RX1A 1PD9A 3K45A 3SRRX 3FRAX 1S3WA 3KJRA 4ELGA 4KJLA 3SRSX 2B3ZA 1DR7A 3DFRA 4KM0A 1RD7A 5HT4A 1DREA 3CSEA 1RA9A 3DRCA 4KNEA 1DRBA 2HM9A 1RC4A 3JW3A 4XT5A 4ELEA 1DF7A 1VDRA 3JVXA 3IA4A 2D0KA 1HFRA 3F0XX 3DAUA 1RX5A 2OBCA 3IA5A 2W9SA 1KMVA 1RX9A 4HOEA 2C2TA 3NXRA 1DG7A 3FRBX 4KY8A 4QHVA 2AZNA 4I1NA 1DYRA 1DHIA 3SA2A 4LAHX 3NZ9X 2W9GA 1U70A 3GHWA 1RX3A 3CLBA 4HOGA 4DDRA 3JWMA 3NZCX 3FY8X 3FS6A 3M09A 3ZPCA 1RE7A 3EEMA 1HFPA 1RX4A 1DLSA 4H96A 4Q67A 3UM8A 1DRAA 3SR5X 1U72A 1IA1A 4KM2A 4EJ1A 4X5GA 5CC9A 3TQ9A 3NRRA 4LEKX 4DFRA 2L28A 5HSUA 1RB3A 4M6JA 1DYHA 5CCCA 3SA1A 4M7VA 4EILA 4X5FA 3DG8A 4DPDA 5DFRA 1DR4A 1DR5A 1RB2A 4HOFA 1DG8A 2CIGA 4DPHA 4KL9A 4X5HA 1E26A 1RG7A 3S9UA 3S7AA 1HFQA 5HQYA 4Q6AA 3FL9A 3QYOA 3DATA 3GHVA 4PTHA 5JA3A 3QLSA 4EIGA 4QI9A 4M6KA 1LUDA 3QG2A 1IA3A 3NU0A 3QYLA 4CD2A 1RX8A 3F0UX 1KLKA 3F0QX 4KYAA
chains in the Genus database with same CATH superfamily
2BL9A 3EEKA 1DR1A 3UM5A 4ELFA 3CL9A 1RA8A 3GI2A 1CZ3A 3M08A 1AI9A 3F0SX 3RG9A 3TQBA 3K47A 2FZHA 1DHJA 2ITHA 3KFYA 4IXFX 3DGAA 4P3RA 1MVSA 4XE6X 1BZFA 3FYWX 3F8YA 4LAEX 3NZ6X 1ZDRA 3ZPGA 1D1GA 3NZBX 3GYFA 1JUVA 1VJ3A 2QK8A 3DL6A 7DFRA 1AOEA 2W3VA 3OCHA 4PTJA 1RF7A 5E8QA 3Q1HA 2FZJA 3JWFA 3SGYA 3ROAA 3CD2A 3EIGA 5ECXA 1U71A 4XRBA 4GH8A 5HUIA 1YHOA 4KAKA 3NZDA 5DXVA 2CD2A 3VCOA 1PDBA 3IRNA 1DRHA 4LAGX 4KJKA 4KJJA 3TD8A 5HF0X 4DP3A 3NZAX 3FREX 3N0HA 4P68A 4IXED 2O7PA 1DYJA 4H98A 1IA2A 3FQOA 5HQZA 2OIPA 1DRFA 2INQA 3NTZA 4FHBA 1JOMA 1DR2A 5HI6A 4H97A 2ZZAA 4H95A 4NX7A 2W3WA 2JYBA 3FQ0A 1DG5A 3IROA 4I13A 4QLEA 3NXOA 1DDSA 1M7AA 2C2SA 1PD8A 3HJ3A 3NXXA 3QLYA 1DAJA 5HT5A 2DHFA 4HA9A 1LY4A 4NX6A 1RX6A 1DHFA 1SEJA 2ANOA 4PDJA 1RA1A 3TQAA 3E0BA 5JG0X 3UM6A 1QZFA 3SAIA 1S3UA 3F91A 3OAFA 5HPBA 3EELA 1DISA 3NXVA 3FRFX 4ELHA 1JOLA 5HVBA 1RH3A 5EAJA 1BOZA 4FGHA 4M6LA 3S3VA 4RGCA 8DFRA 1DYIA 3QL3A 5HSRA 3SRWX 4QLGA 4M7UA 3KY8A 2G6VA 3QLWA 4Q0DA 1DIUA 3I3RA 4X5IA 1KMSA 3K74A 4M2XA 3DL5A 5U26A 3TQ8A 3FQCA 3QLXA 2LF1A 4QLFA 1TDRA 2D5NA 3IX9A 3F0BX 2XW7A 4G3MA 4QJCA 4OSGA 2BLAA 5HVEA 4QJZD 3FRDX 3INVA 5FDAA 3FQFA 5ECCA 1DR3A 4Q0EA 2GD9A 1J3KA 4KEBA 2DRCA 4ELBA 3QLRA 2W9TA 3I8AX 1S3VA 2HXVA 3SRUX 3QFXA 1LY3A 1RX2A 3SQYX 3F0VX 1DLRA 1RA2A 4KBNA 4XT8A 3QL0A 5U27A 4IXGX 3L3RA 4FGGA 4X5JA 3SH2A 6DFRA 3FQZA 3KJSA 1DR6A 3FYVX 3R33A 2W3BA 1AO8A 1M79A 3K2HA 4G8ZX 1OHKA 1J3JA 3JW5A 2KGKA 4XT6A 4PSTA 3NXTA 3EX8A 2ANQA 4XECX 4KY4A 1S3YA 4EIZA 3HBBA 3JWKA 2W9HA 3KGYA 3FQVA 4TU5X 3JWCA 4XT7A 3RO9A 2W3MA 1M78A 3SRQX 4HA7A 3IRMA 2P4GA 3D80A 1CD2A 5HF2X 4KLXA 3D84X 2FZIA 1MVTA 3LG4A 3FY9X 4KFJA 4KD7A 2BLBA 4PSSA 3F8ZA 3EEJA 3JSUA 4G95A 3JTWA 3QLZA 2HQPA 3FL8A 4PSYA 1J3IA 2BLCA 1RX7A 4P3QA 1DDRA 2H2QA 1IA4A 4ECKA 3NXYA 4P66A 1OHJA 4XT4A 3GHCA 2W3AA 1RA3A 3QGTA 4OR7A 1RX1A 1PD9A 3K45A 3SRRX 3FRAX 1S3WA 3KJRA 4ELGA 4KJLA 3SRSX 2B3ZA 1DR7A 3DFRA 4KM0A 1RD7A 5HT4A 1DREA 3CSEA 1RA9A 3DRCA 4KNEA 1DRBA 2HM9A 1RC4A 3JW3A 4XT5A 4ELEA 1DF7A 1VDRA 3JVXA 3IA4A 2D0KA 1HFRA 3F0XX 3DAUA 1RX5A 2OBCA 3IA5A 2W9SA 1KMVA 1RX9A 4HOEA 2C2TA 3NXRA 1DG7A 3FRBX 4KY8A 4QHVA 2AZNA 4I1NA 1DYRA 1DHIA 3SA2A 4LAHX 3NZ9X 2W9GA 1U70A 3GHWA 1RX3A 3CLBA 4HOGA 4DDRA 3JWMA 3NZCX 3FY8X 3FS6A 3M09A 3ZPCA 1RE7A 3EEMA 1HFPA 1RX4A 1DLSA 4H96A 4Q67A 3UM8A 1DRAA 3SR5X 1U72A 1IA1A 4KM2A 4EJ1A 4X5GA 5CC9A 3TQ9A 3NRRA 4LEKX 4DFRA 2L28A 5HSUA 1RB3A 4M6JA 1DYHA 5CCCA 3SA1A 4M7VA 4EILA 4X5FA 3DG8A 4DPDA 5DFRA 1DR4A 1DR5A 1RB2A 4HOFA 1DG8A 2CIGA 4DPHA 4KL9A 4X5HA 1E26A 1RG7A 3S9UA 3S7AA 1HFQA 5HQYA 4Q6AA 3FL9A 3QYOA 3DATA 3GHVA 4PTHA 5JA3A 3QLSA 4EIGA 4QI9A 4M6KA 1LUDA 3QG2A 1IA3A 3NU0A 3QYLA 4CD2A 1RX8A 3F0UX 1KLKA 3F0QX 4KYAA
chains in the Genus database with same CATH topology
2BL9A 3EEKA 1DR1A 3UM5A 4ELFA 3CL9A 1RA8A 3GI2A 1CZ3A 3M08A 1AI9A 3F0SX 3RG9A 3TQBA 3K47A 2FZHA 1DHJA 2ITHA 3KFYA 4IXFX 3DGAA 4P3RA 1MVSA 4XE6X 1BZFA 3FYWX 3F8YA 4LAEX 3NZ6X 1ZDRA 3ZPGA 1D1GA 3NZBX 3GYFA 1JUVA 1VJ3A 2QK8A 3DL6A 7DFRA 1AOEA 2W3VA 3OCHA 4PTJA 1RF7A 5E8QA 3Q1HA 2FZJA 3JWFA 3SGYA 3ROAA 3CD2A 3EIGA 5ECXA 1U71A 4XRBA 4GH8A 5HUIA 1YHOA 4KAKA 3NZDA 5DXVA 2CD2A 3VCOA 1PDBA 3IRNA 1DRHA 4LAGX 4KJKA 4KJJA 3TD8A 5HF0X 4DP3A 3NZAX 3FREX 3N0HA 4P68A 4IXED 2O7PA 1DYJA 4H98A 1IA2A 3FQOA 5HQZA 2OIPA 1DRFA 2INQA 3NTZA 4FHBA 1JOMA 1DR2A 5HI6A 4H97A 2ZZAA 4H95A 4NX7A 2W3WA 2JYBA 3FQ0A 1DG5A 3IROA 4I13A 4QLEA 3NXOA 1DDSA 1M7AA 2C2SA 1PD8A 3HJ3A 3NXXA 3QLYA 1DAJA 5HT5A 2DHFA 4HA9A 1LY4A 4NX6A 1RX6A 1DHFA 1SEJA 2ANOA 4PDJA 1RA1A 3TQAA 3E0BA 5JG0X 3UM6A 1QZFA 3SAIA 1S3UA 3F91A 3OAFA 5HPBA 3EELA 1DISA 3NXVA 3FRFX 4ELHA 1JOLA 5HVBA 1RH3A 5EAJA 1BOZA 4FGHA 4M6LA 3S3VA 4RGCA 8DFRA 1DYIA 3QL3A 5HSRA 3SRWX 4QLGA 4M7UA 3KY8A 2G6VA 3QLWA 4Q0DA 1DIUA 3I3RA 4X5IA 1KMSA 3K74A 4M2XA 3DL5A 5U26A 3TQ8A 3FQCA 3QLXA 2LF1A 4QLFA 1TDRA 2D5NA 3IX9A 3F0BX 2XW7A 4G3MA 4QJCA 4OSGA 2BLAA 5HVEA 4QJZD 3FRDX 3INVA 5FDAA 3FQFA 5ECCA 1DR3A 4Q0EA 2GD9A 1J3KA 4KEBA 2DRCA 4ELBA 3QLRA 2W9TA 3I8AX 1S3VA 2HXVA 3SRUX 3QFXA 1LY3A 1RX2A 3SQYX 3F0VX 1DLRA 1RA2A 4KBNA 4XT8A 3QL0A 5U27A 4IXGX 3L3RA 4FGGA 4X5JA 3SH2A 6DFRA 3FQZA 3KJSA 1DR6A 3FYVX 3R33A 2W3BA 1AO8A 1M79A 3K2HA 4G8ZX 1OHKA 1J3JA 3JW5A 2KGKA 4XT6A 4PSTA 3NXTA 3EX8A 2ANQA 4XECX 4KY4A 1S3YA 4EIZA 3HBBA 3JWKA 2W9HA 3KGYA 3FQVA 4TU5X 3JWCA 4XT7A 3RO9A 2W3MA 1M78A 3SRQX 4HA7A 3IRMA 2P4GA 3D80A 1CD2A 5HF2X 4KLXA 3D84X 2FZIA 1MVTA 3LG4A 3FY9X 4KFJA 4KD7A 2BLBA 4PSSA 3F8ZA 3EEJA 3JSUA 4G95A 3JTWA 3QLZA 2HQPA 3FL8A 4PSYA 1J3IA 2BLCA 1RX7A 4P3QA 1DDRA 2H2QA 1IA4A 4ECKA 3NXYA 4P66A 1OHJA 4XT4A 3GHCA 2W3AA 1RA3A 3QGTA 4OR7A 1RX1A 1PD9A 3K45A 3SRRX 3FRAX 1S3WA 3KJRA 4ELGA 4KJLA 3SRSX 2B3ZA 1DR7A 3DFRA 4KM0A 1RD7A 5HT4A 1DREA 3CSEA 1RA9A 3DRCA 4KNEA 1DRBA 2HM9A 1RC4A 3JW3A 4XT5A 4ELEA 1DF7A 1VDRA 3JVXA 3IA4A 2D0KA 1HFRA 3F0XX 3DAUA 1RX5A 2OBCA 3IA5A 2W9SA 1KMVA 1RX9A 4HOEA 2C2TA 3NXRA 1DG7A 3FRBX 4KY8A 4QHVA 2AZNA 4I1NA 1DYRA 1DHIA 3SA2A 4LAHX 3NZ9X 2W9GA 1U70A 3GHWA 1RX3A 3CLBA 4HOGA 4DDRA 3JWMA 3NZCX 3FY8X 3FS6A 3M09A 3ZPCA 1RE7A 3EEMA 1HFPA 1RX4A 1DLSA 4H96A 4Q67A 3UM8A 1DRAA 3SR5X 1U72A 1IA1A 4KM2A 4EJ1A 4X5GA 5CC9A 3TQ9A 3NRRA 4LEKX 4DFRA 2L28A 5HSUA 1RB3A 4M6JA 1DYHA 5CCCA 3SA1A 4M7VA 4EILA 4X5FA 3DG8A 4DPDA 5DFRA 1DR4A 1DR5A 1RB2A 4HOFA 1DG8A 2CIGA 4DPHA 4KL9A 4X5HA 1E26A 1RG7A 3S9UA 3S7AA 1HFQA 5HQYA 4Q6AA 3FL9A 3QYOA 3DATA 3GHVA 4PTHA 5JA3A 3QLSA 4EIGA 4QI9A 4M6KA 1LUDA 3QG2A 1IA3A 3NU0A 3QYLA 4CD2A 1RX8A 3F0UX 1KLKA 3F0QX 4KYAA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2BL9 A;  3EEK A;  1DR1 A;  3UM5 A;  4ELF A;  3CL9 A;  1RA8 A;  3GI2 A;  1CZ3 A;  3M08 A;  1AI9 A;  3F0S X;  3RG9 A;  3TQB A;  3K47 A;  2FZH A;  1DHJ A;  2ITH A;  3KFY A;  4IXF X;  3DGA A;  4P3R A;  1MVS A;  4XE6 X;  1BZF A;  3FYW X;  3F8Y A;  4LAE X;  3NZ6 X;  1ZDR A;  3ZPG A;  1D1G A;  3NZB X;  3GYF A;  1JUV A;  1VJ3 A;  2QK8 A;  3DL6 A;  7DFR A;  1AOE A;  2W3V A;  3OCH A;  4PTJ A;  1RF7 A;  5E8Q A;  3Q1H A;  2FZJ A;  3JWF A;  3SGY A;  3ROA A;  3CD2 A;  3EIG A;  5ECX A;  1U71 A;  4XRB A;  4GH8 A;  5HUI A;  1YHO A;  4KAK A;  3NZD A;  5DXV A;  2CD2 A;  3VCO A;  1PDB A;  3IRN A;  1DRH A;  4LAG X;  4KJK A;  4KJJ A;  3TD8 A;  5HF0 X;  4DP3 A;  3NZA X;  3FRE X;  3N0H A;  4P68 A;  4IXE D;  2O7P A;  1DYJ A;  4H98 A;  1IA2 A;  3FQO A;  5HQZ A;  2OIP A;  1DRF A;  2INQ A;  3NTZ A;  4FHB A;  1JOM A;  1DR2 A;  5HI6 A;  4H97 A;  2ZZA A;  4H95 A;  4NX7 A;  2W3W A;  2JYB A;  3FQ0 A;  1DG5 A;  3IRO A;  4I13 A;  4QLE A;  3NXO A;  1DDS A;  1M7A A;  2C2S A;  1PD8 A;  3HJ3 A;  3NXX A;  3QLY A;  1DAJ A;  5HT5 A;  2DHF A;  4HA9 A;  1LY4 A;  4NX6 A;  1RX6 A;  1DHF A;  1SEJ A;  2ANO A;  4PDJ A;  1RA1 A;  3TQA A;  3E0B A;  5JG0 X;  3UM6 A;  1QZF A;  3SAI A;  1S3U A;  3F91 A;  3OAF A;  5HPB A;  3EEL A;  1DIS A;  3NXV A;  3FRF X;  4ELH A;  1JOL A;  5HVB A;  1RH3 A;  5EAJ A;  1BOZ A;  4FGH A;  4M6L A;  3S3V A;  4RGC A;  8DFR A;  1DYI A;  3QL3 A;  5HSR A;  3SRW X;  4QLG A;  4M7U A;  3KY8 A;  2G6V A;  3QLW A;  4Q0D A;  1DIU A;  3I3R A;  4X5I A;  1KMS A;  3K74 A;  4M2X A;  3DL5 A;  5U26 A;  3TQ8 A;  3FQC A;  3QLX A;  2LF1 A;  4QLF A;  1TDR A;  2D5N A;  3IX9 A;  3F0B X;  2XW7 A;  4G3M A;  4QJC A;  4OSG A;  2BLA A;  5HVE A;  4QJZ D;  3FRD X;  3INV A;  5FDA A;  3FQF A;  5ECC A;  1DR3 A;  4Q0E A;  2GD9 A;  1J3K A;  4KEB A;  2DRC A;  4ELB A;  3QLR A;  2W9T A;  3I8A X;  1S3V A;  2HXV A;  3SRU X;  3QFX A;  1LY3 A;  1RX2 A;  3SQY X;  3F0V X;  1DLR A;  1RA2 A;  4KBN A;  4XT8 A;  3QL0 A;  5U27 A;  4IXG X;  3L3R A;  4FGG A;  4X5J A;  3SH2 A;  6DFR A;  3FQZ A;  3KJS A;  1DR6 A;  3FYV X;  3R33 A;  2W3B A;  1AO8 A;  1M79 A;  3K2H A;  4G8Z X;  1OHK A;  1J3J A;  3JW5 A;  2KGK A;  4XT6 A;  4PST A;  3NXT A;  3EX8 A;  2ANQ A;  4XEC X;  4KY4 A;  1S3Y A;  4EIZ A;  3HBB A;  3JWK A;  2W9H A;  3KGY A;  3FQV A;  4TU5 X;  3JWC A;  4XT7 A;  3RO9 A;  2W3M A;  1M78 A;  3SRQ X;  4HA7 A;  3IRM A;  2P4G A;  3D80 A;  1CD2 A;  5HF2 X;  4KLX A;  3D84 X;  2FZI A;  1MVT A;  3LG4 A;  3FY9 X;  4KFJ A;  4KD7 A;  2BLB A;  4PSS A;  3F8Z A;  3EEJ A;  3JSU A;  4G95 A;  3JTW A;  3QLZ A;  2HQP A;  3FL8 A;  4PSY A;  1J3I A;  2BLC A;  1RX7 A;  4P3Q A;  1DDR A;  2H2Q A;  1IA4 A;  4ECK A;  3NXY A;  4P66 A;  1OHJ A;  4XT4 A;  3GHC A;  2W3A A;  1RA3 A;  3QGT A;  4OR7 A;  1RX1 A;  1PD9 A;  3K45 A;  3SRR X;  3FRA X;  1S3W A;  3KJR A;  4ELG A;  4KJL A;  3SRS X;  2B3Z A;  1DR7 A;  3DFR A;  4KM0 A;  1RD7 A;  5HT4 A;  1DRE A;  3CSE A;  1RA9 A;  3DRC A;  4KNE A;  1DRB A;  2HM9 A;  1RC4 A;  3JW3 A;  4XT5 A;  4ELE A;  1DF7 A;  1VDR A;  3JVX A;  3IA4 A;  2D0K A;  1HFR A;  3F0X X;  3DAU A;  1RX5 A;  2OBC A;  3IA5 A;  2W9S A;  1KMV A;  1RX9 A;  4HOE A;  2C2T A;  3NXR A;  1DG7 A;  3FRB X;  4KY8 A;  4QHV A;  2AZN A;  4I1N A;  1DYR A;  1DHI A;  3SA2 A;  4LAH X;  3NZ9 X;  2W9G A;  1U70 A;  3GHW A;  1RX3 A;  3CLB A;  4HOG A;  4DDR A;  3JWM A;  3NZC X;  3FY8 X;  3FS6 A;  3M09 A;  3ZPC A;  1RE7 A;  3EEM A;  1HFP A;  1RX4 A;  1DLS A;  4H96 A;  4Q67 A;  3UM8 A;  1DRA A;  3SR5 X;  1U72 A;  1IA1 A;  4KM2 A;  4EJ1 A;  4X5G A;  5CC9 A;  3TQ9 A;  3NRR A;  4LEK X;  4DFR A;  2L28 A;  5HSU A;  1RB3 A;  4M6J A;  1DYH A;  5CCC A;  3SA1 A;  4M7V A;  4EIL A;  4X5F A;  3DG8 A;  4DPD A;  5DFR A;  1DR4 A;  1DR5 A;  1RB2 A;  4HOF A;  1DG8 A;  2CIG A;  4DPH A;  4KL9 A;  4X5H A;  1E26 A;  1RG7 A;  3S9U A;  3S7A A;  1HFQ A;  5HQY A;  4Q6A A;  3FL9 A;  3QYO A;  3DAT A;  3GHV A;  4PTH A;  5JA3 A;  3QLS A;  4EIG A;  4QI9 A;  4M6K A;  1LUD A;  3QG2 A;  1IA3 A;  3NU0 A;  3QYL A;  4CD2 A;  1RX8 A;  3F0U X;  1KLK A;  3F0Q X;  4KYA A; 
#chains in the Genus database with same CATH topology
 2BL9 A;  3EEK A;  1DR1 A;  3UM5 A;  4ELF A;  3CL9 A;  1RA8 A;  3GI2 A;  1CZ3 A;  3M08 A;  1AI9 A;  3F0S X;  3RG9 A;  3TQB A;  3K47 A;  2FZH A;  1DHJ A;  2ITH A;  3KFY A;  4IXF X;  3DGA A;  4P3R A;  1MVS A;  4XE6 X;  1BZF A;  3FYW X;  3F8Y A;  4LAE X;  3NZ6 X;  1ZDR A;  3ZPG A;  1D1G A;  3NZB X;  3GYF A;  1JUV A;  1VJ3 A;  2QK8 A;  3DL6 A;  7DFR A;  1AOE A;  2W3V A;  3OCH A;  4PTJ A;  1RF7 A;  5E8Q A;  3Q1H A;  2FZJ A;  3JWF A;  3SGY A;  3ROA A;  3CD2 A;  3EIG A;  5ECX A;  1U71 A;  4XRB A;  4GH8 A;  5HUI A;  1YHO A;  4KAK A;  3NZD A;  5DXV A;  2CD2 A;  3VCO A;  1PDB A;  3IRN A;  1DRH A;  4LAG X;  4KJK A;  4KJJ A;  3TD8 A;  5HF0 X;  4DP3 A;  3NZA X;  3FRE X;  3N0H A;  4P68 A;  4IXE D;  2O7P A;  1DYJ A;  4H98 A;  1IA2 A;  3FQO A;  5HQZ A;  2OIP A;  1DRF A;  2INQ A;  3NTZ A;  4FHB A;  1JOM A;  1DR2 A;  5HI6 A;  4H97 A;  2ZZA A;  4H95 A;  4NX7 A;  2W3W A;  2JYB A;  3FQ0 A;  1DG5 A;  3IRO A;  4I13 A;  4QLE A;  3NXO A;  1DDS A;  1M7A A;  2C2S A;  1PD8 A;  3HJ3 A;  3NXX A;  3QLY A;  1DAJ A;  5HT5 A;  2DHF A;  4HA9 A;  1LY4 A;  4NX6 A;  1RX6 A;  1DHF A;  1SEJ A;  2ANO A;  4PDJ A;  1RA1 A;  3TQA A;  3E0B A;  5JG0 X;  3UM6 A;  1QZF A;  3SAI A;  1S3U A;  3F91 A;  3OAF A;  5HPB A;  3EEL A;  1DIS A;  3NXV A;  3FRF X;  4ELH A;  1JOL A;  5HVB A;  1RH3 A;  5EAJ A;  1BOZ A;  4FGH A;  4M6L A;  3S3V A;  4RGC A;  8DFR A;  1DYI A;  3QL3 A;  5HSR A;  3SRW X;  4QLG A;  4M7U A;  3KY8 A;  2G6V A;  3QLW A;  4Q0D A;  1DIU A;  3I3R A;  4X5I A;  1KMS A;  3K74 A;  4M2X A;  3DL5 A;  5U26 A;  3TQ8 A;  3FQC A;  3QLX A;  2LF1 A;  4QLF A;  1TDR A;  2D5N A;  3IX9 A;  3F0B X;  2XW7 A;  4G3M A;  4QJC A;  4OSG A;  2BLA A;  5HVE A;  4QJZ D;  3FRD X;  3INV A;  5FDA A;  3FQF A;  5ECC A;  1DR3 A;  4Q0E A;  2GD9 A;  1J3K A;  4KEB A;  2DRC A;  4ELB A;  3QLR A;  2W9T A;  3I8A X;  1S3V A;  2HXV A;  3SRU X;  3QFX A;  1LY3 A;  1RX2 A;  3SQY X;  3F0V X;  1DLR A;  1RA2 A;  4KBN A;  4XT8 A;  3QL0 A;  5U27 A;  4IXG X;  3L3R A;  4FGG A;  4X5J A;  3SH2 A;  6DFR A;  3FQZ A;  3KJS A;  1DR6 A;  3FYV X;  3R33 A;  2W3B A;  1AO8 A;  1M79 A;  3K2H A;  4G8Z X;  1OHK A;  1J3J A;  3JW5 A;  2KGK A;  4XT6 A;  4PST A;  3NXT A;  3EX8 A;  2ANQ A;  4XEC X;  4KY4 A;  1S3Y A;  4EIZ A;  3HBB A;  3JWK A;  2W9H A;  3KGY A;  3FQV A;  4TU5 X;  3JWC A;  4XT7 A;  3RO9 A;  2W3M A;  1M78 A;  3SRQ X;  4HA7 A;  3IRM A;  2P4G A;  3D80 A;  1CD2 A;  5HF2 X;  4KLX A;  3D84 X;  2FZI A;  1MVT A;  3LG4 A;  3FY9 X;  4KFJ A;  4KD7 A;  2BLB A;  4PSS A;  3F8Z A;  3EEJ A;  3JSU A;  4G95 A;  3JTW A;  3QLZ A;  2HQP A;  3FL8 A;  4PSY A;  1J3I A;  2BLC A;  1RX7 A;  4P3Q A;  1DDR A;  2H2Q A;  1IA4 A;  4ECK A;  3NXY A;  4P66 A;  1OHJ A;  4XT4 A;  3GHC A;  2W3A A;  1RA3 A;  3QGT A;  4OR7 A;  1RX1 A;  1PD9 A;  3K45 A;  3SRR X;  3FRA X;  1S3W A;  3KJR A;  4ELG A;  4KJL A;  3SRS X;  2B3Z A;  1DR7 A;  3DFR A;  4KM0 A;  1RD7 A;  5HT4 A;  1DRE A;  3CSE A;  1RA9 A;  3DRC A;  4KNE A;  1DRB A;  2HM9 A;  1RC4 A;  3JW3 A;  4XT5 A;  4ELE A;  1DF7 A;  1VDR A;  3JVX A;  3IA4 A;  2D0K A;  1HFR A;  3F0X X;  3DAU A;  1RX5 A;  2OBC A;  3IA5 A;  2W9S A;  1KMV A;  1RX9 A;  4HOE A;  2C2T A;  3NXR A;  1DG7 A;  3FRB X;  4KY8 A;  4QHV A;  2AZN A;  4I1N A;  1DYR A;  1DHI A;  3SA2 A;  4LAH X;  3NZ9 X;  2W9G A;  1U70 A;  3GHW A;  1RX3 A;  3CLB A;  4HOG A;  4DDR A;  3JWM A;  3NZC X;  3FY8 X;  3FS6 A;  3M09 A;  3ZPC A;  1RE7 A;  3EEM A;  1HFP A;  1RX4 A;  1DLS A;  4H96 A;  4Q67 A;  3UM8 A;  1DRA A;  3SR5 X;  1U72 A;  1IA1 A;  4KM2 A;  4EJ1 A;  4X5G A;  5CC9 A;  3TQ9 A;  3NRR A;  4LEK X;  4DFR A;  2L28 A;  5HSU A;  1RB3 A;  4M6J A;  1DYH A;  5CCC A;  3SA1 A;  4M7V A;  4EIL A;  4X5F A;  3DG8 A;  4DPD A;  5DFR A;  1DR4 A;  1DR5 A;  1RB2 A;  4HOF A;  1DG8 A;  2CIG A;  4DPH A;  4KL9 A;  4X5H A;  1E26 A;  1RG7 A;  3S9U A;  3S7A A;  1HFQ A;  5HQY A;  4Q6A A;  3FL9 A;  3QYO A;  3DAT A;  3GHV A;  4PTH A;  5JA3 A;  3QLS A;  4EIG A;  4QI9 A;  4M6K A;  1LUD A;  3QG2 A;  1IA3 A;  3NU0 A;  3QYL A;  4CD2 A;  1RX8 A;  3F0U X;  1KLK A;  3F0Q X;  4KYA A; 
#chains in the Genus database with same CATH homology
 2BL9 A;  3EEK A;  1DR1 A;  3UM5 A;  4ELF A;  3CL9 A;  1RA8 A;  3GI2 A;  1CZ3 A;  3M08 A;  1AI9 A;  3F0S X;  3RG9 A;  3TQB A;  3K47 A;  2FZH A;  1DHJ A;  2ITH A;  3KFY A;  4IXF X;  3DGA A;  4P3R A;  1MVS A;  4XE6 X;  1BZF A;  3FYW X;  3F8Y A;  4LAE X;  3NZ6 X;  1ZDR A;  3ZPG A;  1D1G A;  3NZB X;  3GYF A;  1JUV A;  1VJ3 A;  2QK8 A;  3DL6 A;  7DFR A;  1AOE A;  2W3V A;  3OCH A;  4PTJ A;  1RF7 A;  5E8Q A;  3Q1H A;  2FZJ A;  3JWF A;  3SGY A;  3ROA A;  3CD2 A;  3EIG A;  5ECX A;  1U71 A;  4XRB A;  4GH8 A;  5HUI A;  1YHO A;  4KAK A;  3NZD A;  5DXV A;  2CD2 A;  3VCO A;  1PDB A;  3IRN A;  1DRH A;  4LAG X;  4KJK A;  4KJJ A;  3TD8 A;  5HF0 X;  4DP3 A;  3NZA X;  3FRE X;  3N0H A;  4P68 A;  4IXE D;  2O7P A;  1DYJ A;  4H98 A;  1IA2 A;  3FQO A;  5HQZ A;  2OIP A;  1DRF A;  2INQ A;  3NTZ A;  4FHB A;  1JOM A;  1DR2 A;  5HI6 A;  4H97 A;  2ZZA A;  4H95 A;  4NX7 A;  2W3W A;  2JYB A;  3FQ0 A;  1DG5 A;  3IRO A;  4I13 A;  4QLE A;  3NXO A;  1DDS A;  1M7A A;  2C2S A;  1PD8 A;  3HJ3 A;  3NXX A;  3QLY A;  1DAJ A;  5HT5 A;  2DHF A;  4HA9 A;  1LY4 A;  4NX6 A;  1RX6 A;  1DHF A;  1SEJ A;  2ANO A;  4PDJ A;  1RA1 A;  3TQA A;  3E0B A;  5JG0 X;  3UM6 A;  1QZF A;  3SAI A;  1S3U A;  3F91 A;  3OAF A;  5HPB A;  3EEL A;  1DIS A;  3NXV A;  3FRF X;  4ELH A;  1JOL A;  5HVB A;  1RH3 A;  5EAJ A;  1BOZ A;  4FGH A;  4M6L A;  3S3V A;  4RGC A;  8DFR A;  1DYI A;  3QL3 A;  5HSR A;  3SRW X;  4QLG A;  4M7U A;  3KY8 A;  2G6V A;  3QLW A;  4Q0D A;  1DIU A;  3I3R A;  4X5I A;  1KMS A;  3K74 A;  4M2X A;  3DL5 A;  5U26 A;  3TQ8 A;  3FQC A;  3QLX A;  2LF1 A;  4QLF A;  1TDR A;  2D5N A;  3IX9 A;  3F0B X;  2XW7 A;  4G3M A;  4QJC A;  4OSG A;  2BLA A;  5HVE A;  4QJZ D;  3FRD X;  3INV A;  5FDA A;  3FQF A;  5ECC A;  1DR3 A;  4Q0E A;  2GD9 A;  1J3K A;  4KEB A;  2DRC A;  4ELB A;  3QLR A;  2W9T A;  3I8A X;  1S3V A;  2HXV A;  3SRU X;  3QFX A;  1LY3 A;  1RX2 A;  3SQY X;  3F0V X;  1DLR A;  1RA2 A;  4KBN A;  4XT8 A;  3QL0 A;  5U27 A;  4IXG X;  3L3R A;  4FGG A;  4X5J A;  3SH2 A;  6DFR A;  3FQZ A;  3KJS A;  1DR6 A;  3FYV X;  3R33 A;  2W3B A;  1AO8 A;  1M79 A;  3K2H A;  4G8Z X;  1OHK A;  1J3J A;  3JW5 A;  2KGK A;  4XT6 A;  4PST A;  3NXT A;  3EX8 A;  2ANQ A;  4XEC X;  4KY4 A;  1S3Y A;  4EIZ A;  3HBB A;  3JWK A;  2W9H A;  3KGY A;  3FQV A;  4TU5 X;  3JWC A;  4XT7 A;  3RO9 A;  2W3M A;  1M78 A;  3SRQ X;  4HA7 A;  3IRM A;  2P4G A;  3D80 A;  1CD2 A;  5HF2 X;  4KLX A;  3D84 X;  2FZI A;  1MVT A;  3LG4 A;  3FY9 X;  4KFJ A;  4KD7 A;  2BLB A;  4PSS A;  3F8Z A;  3EEJ A;  3JSU A;  4G95 A;  3JTW A;  3QLZ A;  2HQP A;  3FL8 A;  4PSY A;  1J3I A;  2BLC A;  1RX7 A;  4P3Q A;  1DDR A;  2H2Q A;  1IA4 A;  4ECK A;  3NXY A;  4P66 A;  1OHJ A;  4XT4 A;  3GHC A;  2W3A A;  1RA3 A;  3QGT A;  4OR7 A;  1RX1 A;  1PD9 A;  3K45 A;  3SRR X;  3FRA X;  1S3W A;  3KJR A;  4ELG A;  4KJL A;  3SRS X;  2B3Z A;  1DR7 A;  3DFR A;  4KM0 A;  1RD7 A;  5HT4 A;  1DRE A;  3CSE A;  1RA9 A;  3DRC A;  4KNE A;  1DRB A;  2HM9 A;  1RC4 A;  3JW3 A;  4XT5 A;  4ELE A;  1DF7 A;  1VDR A;  3JVX A;  3IA4 A;  2D0K A;  1HFR A;  3F0X X;  3DAU A;  1RX5 A;  2OBC A;  3IA5 A;  2W9S A;  1KMV A;  1RX9 A;  4HOE A;  2C2T A;  3NXR A;  1DG7 A;  3FRB X;  4KY8 A;  4QHV A;  2AZN A;  4I1N A;  1DYR A;  1DHI A;  3SA2 A;  4LAH X;  3NZ9 X;  2W9G A;  1U70 A;  3GHW A;  1RX3 A;  3CLB A;  4HOG A;  4DDR A;  3JWM A;  3NZC X;  3FY8 X;  3FS6 A;  3M09 A;  3ZPC A;  1RE7 A;  3EEM A;  1HFP A;  1RX4 A;  1DLS A;  4H96 A;  4Q67 A;  3UM8 A;  1DRA A;  3SR5 X;  1U72 A;  1IA1 A;  4KM2 A;  4EJ1 A;  4X5G A;  5CC9 A;  3TQ9 A;  3NRR A;  4LEK X;  4DFR A;  2L28 A;  5HSU A;  1RB3 A;  4M6J A;  1DYH A;  5CCC A;  3SA1 A;  4M7V A;  4EIL A;  4X5F A;  3DG8 A;  4DPD A;  5DFR A;  1DR4 A;  1DR5 A;  1RB2 A;  4HOF A;  1DG8 A;  2CIG A;  4DPH A;  4KL9 A;  4X5H A;  1E26 A;  1RG7 A;  3S9U A;  3S7A A;  1HFQ A;  5HQY A;  4Q6A A;  3FL9 A;  3QYO A;  3DAT A;  3GHV A;  4PTH A;  5JA3 A;  3QLS A;  4EIG A;  4QI9 A;  4M6K A;  1LUD A;  3QG2 A;  1IA3 A;  3NU0 A;  3QYL A;  4CD2 A;  1RX8 A;  3F0U X;  1KLK A;  3F0Q X;  4KYA A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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