2D1GA

Structure of francisella tularensis acid phosphatase a (acpa) bound to orthovanadate
Total Genus 180
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
180
Knots found
sequence length
485
structure length
481
Chain Sequence
NSKPNDYGTLQKLFNNANTLKTTTPIKHVVIIFQENNSFDRYFGMYPNAKNPEGEPKFVAKENTPNVNGLTKQLLENNPNTKNPYRLDRNFQPCSQNHEYHQEISSFNGGLMNKFVEHGGHDNDTYKQNCDGQVMGYYDGNTVTALWNYAQNFALNDNTFGTTFGPSTPGALNLVAGANGPAMSPSGNLENIENNYIIDDPNPYYDDCSYGTSKSGDTNTAVAKITDGYNIGHYLTQKGITWGWFQGGFKPTSYSGKTAICDAMSTNKFGVKSRDYIPHHEPFNYWKETSNPHHLAPSDDKYIGSNDQANHQYDISEFWKALDQNNMPAVSYLKAPGYQDGHGGYSNPLDEQEWLVNTINRIQQSKDWDSTAIIIIYDDSDGDYDHVYSPKSQFSDIKGRQGYGPRLPMLVISPYAKANYVDHSLLNQASVLKFIEYNWGIGSVSKYSNDKYSNNILNMFDFNKEQKTLKLILDPKTGLVM
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structure of Francisella tularensis AcpA: prototype of a unique superfamily of acid phosphatases and phospholipases C
pubmed doi rcsb
source organism Francisella tularensis subsp. novicida
molecule tags Hydrolase
molecule keywords acid phosphatase
total genus 180
structure length 481
sequence length 485
chains with identical sequence B
other databases KnotProt 2.0: S +31
ec nomenclature ec 3.1.3.2: Acid phosphatase.
pdb deposition date 2005-08-20

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF04185 Phosphoesterase Phosphoesterase family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.720.10 Alpha Beta 3-Layer(aba) Sandwich Alkaline Phosphatase, subunit A Alkaline Phosphatase, subunit A 2d1gA02
1B8JA 3IDDA 1SHQA 1ELYA 1FSUA 3WAXA 4MY4A 1KHNA 5TJ3A 1EJJA 2GLQA 4KJDA 2GSOA 5L0EA 1E33P 1N2KA 3MK0A 4LRCA 4ZG6A 2W5WA 2ANHA 1O98A 4UPKA 3MK2A 3UN3A 2W5QA 4CXKA 5LQQA 4QAXA 3OT9A 4KAVA 1E2SP 1KH4A 3NKQA 4NWJA 5INHA 3UO0A 4GTZA 1ED8A 3NKOA 2W5TA 3BDGB 2W5RA 3T00A 4LR9A 3B5QA 1P49A 3NKNA 4KM4A 3LXQA 1HQAA 2IUCB 2IUCA 4FDIA 1K7HA 4LRDA 2W5XA 3SZZA 3IGYB 3E2DA 1ALJA 3WBHA 5DLWA 4LRBA 1AUKA 5DLVA 3Q3QA 4CYSA 1Y7AA 2W5VA 1O99A 3BDHA 3DYCA 1EW2A 3NKMA 4UPHA 4LR2A 5L0KA 2GSUA 1ZEBA 3NKRA 5K4PA 4TN0A 1ALHA 4CXUA 4ZG9A 4CYRA 4GTXA 5KXAA 3A52A 1E3CP 4UOOA 4ZG7A 4LRAA 1ANIA 4UORA 3WAYA 2VQRA 1AJCA 2W8SA 1SHNA 2XR9A 3DPCA 4N7TA 1EQJA 3M7VA 2GA3A 5GOVA 5AJ9A 1EI6A 4FDJA 1HDHA 3TWZA 4LQYA 1EW8A 3KD8A 3WAVA 4CXSA 3T02A 4LR8A 4UPIA 1KHJA 5IJQA 3WAWA 5LRMA 1ANJA 1HJKA 2XRGA 3T01A 2ZKTA 1E1ZP 5EGHA 1ZEDA 3CMRA 5LRNA 3M8ZA 3M8WA 4GTWA 3BDFA 4GTYA 5IJSA 1AJDA 1EW9A 2QZUA 1ALIA 4LR7A 3NKPA 4YR1A 5DLTA 4KAYA 5EGEA 3UN5A 1KH7A 3TG0A 2W5SA 2D1GA 4ZGAA 5L0BA 3ED4A 3NVLA 4LREA 1URBA 1N2LA 3IGZB 4B56A 4UPLA 5GRRA 1URAA 5HRTA 5C66A 1ALKA 3BDGA 1ED9A 4UOPA 2W8DA 4MIVA 3UN2A 1AJAA 1KHLA 1KHKA 1ZEFA 1KH5A 2IFYA 3SZYA 3M8YA 3TX0A 4KJGA 1KH9A 4MHXA 1Y6VA 4LRFA 2G9YA 1ELXA 1ELZA 2X98A 5LIAA 3UNYA 2RH6A 4NWXA 1AJBA 2GSNA 3MK1A
chains in the Genus database with same CATH superfamily
1B8JA 3IDDA 1SHQA 1ELYA 1FSUA 3WAXA 4MY4A 1KHNA 5TJ3A 1EJJA 2GLQA 4KJDA 2GSOA 5L0EA 1E33P 1N2KA 3MK0A 4LRCA 4ZG6A 2W5WA 2ANHA 1O98A 4UPKA 3MK2A 3UN3A 2W5QA 4CXKA 5LQQA 4QAXA 3OT9A 4KAVA 1E2SP 1KH4A 3NKQA 4NWJA 5INHA 3UO0A 4GTZA 1ED8A 3NKOA 2W5TA 3BDGB 2W5RA 3T00A 4LR9A 3B5QA 1P49A 3NKNA 4KM4A 3LXQA 1HQAA 2IUCB 2IUCA 4FDIA 1K7HA 4LRDA 2W5XA 3SZZA 3IGYB 3E2DA 1ALJA 3WBHA 5DLWA 4LRBA 1AUKA 5DLVA 3Q3QA 4CYSA 1Y7AA 2W5VA 1O99A 3BDHA 3DYCA 1EW2A 3NKMA 4UPHA 4LR2A 5L0KA 2GSUA 1ZEBA 3NKRA 5K4PA 4TN0A 1ALHA 4CXUA 4ZG9A 4CYRA 4GTXA 5KXAA 3A52A 1E3CP 4UOOA 4ZG7A 4LRAA 1ANIA 4UORA 3WAYA 2VQRA 1AJCA 2W8SA 1SHNA 2XR9A 3DPCA 4N7TA 1EQJA 3M7VA 2GA3A 5GOVA 5AJ9A 1EI6A 4FDJA 1HDHA 3TWZA 4LQYA 1EW8A 3KD8A 3WAVA 4CXSA 3T02A 4LR8A 4UPIA 1KHJA 5IJQA 3WAWA 5LRMA 1ANJA 1HJKA 2XRGA 3T01A 2ZKTA 1E1ZP 5EGHA 1ZEDA 3CMRA 5LRNA 3M8ZA 3M8WA 4GTWA 3BDFA 4GTYA 5IJSA 1AJDA 1EW9A 2QZUA 1ALIA 4LR7A 3NKPA 4YR1A 5DLTA 4KAYA 5EGEA 3UN5A 1KH7A 3TG0A 2W5SA 2D1GA 4ZGAA 5L0BA 3ED4A 3NVLA 4LREA 1URBA 1N2LA 3IGZB 4B56A 4UPLA 5GRRA 1URAA 5HRTA 5C66A 1ALKA 3BDGA 1ED9A 4UOPA 2W8DA 4MIVA 3UN2A 1AJAA 1KHLA 1KHKA 1ZEFA 1KH5A 2IFYA 3SZYA 3M8YA 3TX0A 4KJGA 1KH9A 4MHXA 1Y6VA 4LRFA 2G9YA 1ELXA 1ELZA 2X98A 5LIAA 3UNYA 2RH6A 4NWXA 1AJBA 2GSNA 3MK1A
chains in the Genus database with same CATH topology
1B8JA 3IDDA 1SHQA 1ELYA 1FSUA 3WAXA 4MY4A 1KHNA 5TJ3A 1EJJA 2GLQA 4KJDA 2GSOA 5L0EA 1E33P 1N2KA 3MK0A 4LRCA 4ZG6A 2W5WA 2ANHA 1O98A 4UPKA 3MK2A 3UN3A 2W5QA 4CXKA 5LQQA 4QAXA 3OT9A 4KAVA 1E2SP 1KH4A 3NKQA 4NWJA 5INHA 3UO0A 4GTZA 1ED8A 3NKOA 2W5TA 3BDGB 2W5RA 3T00A 4LR9A 3B5QA 1P49A 3NKNA 4KM4A 3LXQA 1HQAA 2IUCB 2IUCA 4FDIA 1K7HA 4LRDA 2W5XA 3SZZA 3IGYB 3E2DA 1ALJA 3WBHA 5DLWA 4LRBA 1AUKA 5DLVA 3Q3QA 4CYSA 1Y7AA 2W5VA 1O99A 3BDHA 3DYCA 1EW2A 3NKMA 4UPHA 4LR2A 5L0KA 2GSUA 1ZEBA 3NKRA 5K4PA 4TN0A 1ALHA 4CXUA 4ZG9A 4CYRA 4GTXA 5KXAA 3A52A 1E3CP 4UOOA 4ZG7A 4LRAA 1ANIA 4UORA 3WAYA 2VQRA 1AJCA 2W8SA 1SHNA 2XR9A 3DPCA 4N7TA 1EQJA 3M7VA 2GA3A 5GOVA 5AJ9A 1EI6A 4FDJA 1HDHA 3TWZA 4LQYA 1EW8A 3KD8A 3WAVA 4CXSA 3T02A 4LR8A 4UPIA 1KHJA 5IJQA 3WAWA 5LRMA 1ANJA 1HJKA 2XRGA 3T01A 2ZKTA 1E1ZP 5EGHA 1ZEDA 3CMRA 5LRNA 3M8ZA 3M8WA 4GTWA 3BDFA 4GTYA 5IJSA 1AJDA 1EW9A 2QZUA 1ALIA 4LR7A 3NKPA 4YR1A 5DLTA 4KAYA 5EGEA 3UN5A 1KH7A 3TG0A 2W5SA 2D1GA 4ZGAA 5L0BA 3ED4A 3NVLA 4LREA 1URBA 1N2LA 3IGZB 4B56A 4UPLA 5GRRA 1URAA 5HRTA 5C66A 1ALKA 3BDGA 1ED9A 4UOPA 2W8DA 4MIVA 3UN2A 1AJAA 1KHLA 1KHKA 1ZEFA 1KH5A 2IFYA 3SZYA 3M8YA 3TX0A 4KJGA 1KH9A 4MHXA 1Y6VA 4LRFA 2G9YA 1ELXA 1ELZA 2X98A 5LIAA 3UNYA 2RH6A 4NWXA 1AJBA 2GSNA 3MK1A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1B8J A;  3IDD A;  1SHQ A;  1ELY A;  1FSU A;  3WAX A;  4MY4 A;  1KHN A;  5TJ3 A;  1EJJ A;  2GLQ A;  4KJD A;  2GSO A;  5L0E A;  1E33 P;  1N2K A;  3MK0 A;  4LRC A;  4ZG6 A;  2W5W A;  2ANH A;  1O98 A;  4UPK A;  3MK2 A;  3UN3 A;  2W5Q A;  4CXK A;  5LQQ A;  4QAX A;  3OT9 A;  4KAV A;  1E2S P;  1KH4 A;  3NKQ A;  4NWJ A;  5INH A;  3UO0 A;  4GTZ A;  1ED8 A;  3NKO A;  2W5T A;  3BDG B;  2W5R A;  3T00 A;  4LR9 A;  3B5Q A;  1P49 A;  3NKN A;  4KM4 A;  3LXQ A;  1HQA A;  2IUC B;  2IUC A;  4FDI A;  1K7H A;  4LRD A;  2W5X A;  3SZZ A;  3IGY B;  3E2D A;  1ALJ A;  3WBH A;  5DLW A;  4LRB A;  1AUK A;  5DLV A;  3Q3Q A;  4CYS A;  1Y7A A;  2W5V A;  1O99 A;  3BDH A;  3DYC A;  1EW2 A;  3NKM A;  4UPH A;  4LR2 A;  5L0K A;  2GSU A;  1ZEB A;  3NKR A;  5K4P A;  4TN0 A;  1ALH A;  4CXU A;  4ZG9 A;  4CYR A;  4GTX A;  5KXA A;  3A52 A;  1E3C P;  4UOO A;  4ZG7 A;  4LRA A;  1ANI A;  4UOR A;  3WAY A;  2VQR A;  1AJC A;  2W8S A;  1SHN A;  2XR9 A;  3DPC A;  4N7T A;  1EQJ A;  3M7V A;  2GA3 A;  5GOV A;  5AJ9 A;  1EI6 A;  4FDJ A;  1HDH A;  3TWZ A;  4LQY A;  1EW8 A;  3KD8 A;  3WAV A;  4CXS A;  3T02 A;  4LR8 A;  4UPI A;  1KHJ A;  5IJQ A;  3WAW A;  5LRM A;  1ANJ A;  1HJK A;  2XRG A;  3T01 A;  2ZKT A;  1E1Z P;  5EGH A;  1ZED A;  3CMR A;  5LRN A;  3M8Z A;  3M8W A;  4GTW A;  3BDF A;  4GTY A;  5IJS A;  1AJD A;  1EW9 A;  2QZU A;  1ALI A;  4LR7 A;  3NKP A;  4YR1 A;  5DLT A;  4KAY A;  5EGE A;  3UN5 A;  1KH7 A;  3TG0 A;  2W5S A;  2D1G A;  4ZGA A;  5L0B A;  3ED4 A;  3NVL A;  4LRE A;  1URB A;  1N2L A;  3IGZ B;  4B56 A;  4UPL A;  5GRR A;  1URA A;  5HRT A;  5C66 A;  1ALK A;  3BDG A;  1ED9 A;  4UOP A;  2W8D A;  4MIV A;  3UN2 A;  1AJA A;  1KHL A;  1KHK A;  1ZEF A;  1KH5 A;  2IFY A;  3SZY A;  3M8Y A;  3TX0 A;  4KJG A;  1KH9 A;  4MHX A;  1Y6V A;  4LRF A;  2G9Y A;  1ELX A;  1ELZ A;  2X98 A;  5LIA A;  3UNY A;  2RH6 A;  4NWX A;  1AJB A;  2GSN A;  3MK1 A; 
#chains in the Genus database with same CATH topology
 1B8J A;  3IDD A;  1SHQ A;  1ELY A;  1FSU A;  3WAX A;  4MY4 A;  1KHN A;  5TJ3 A;  1EJJ A;  2GLQ A;  4KJD A;  2GSO A;  5L0E A;  1E33 P;  1N2K A;  3MK0 A;  4LRC A;  4ZG6 A;  2W5W A;  2ANH A;  1O98 A;  4UPK A;  3MK2 A;  3UN3 A;  2W5Q A;  4CXK A;  5LQQ A;  4QAX A;  3OT9 A;  4KAV A;  1E2S P;  1KH4 A;  3NKQ A;  4NWJ A;  5INH A;  3UO0 A;  4GTZ A;  1ED8 A;  3NKO A;  2W5T A;  3BDG B;  2W5R A;  3T00 A;  4LR9 A;  3B5Q A;  1P49 A;  3NKN A;  4KM4 A;  3LXQ A;  1HQA A;  2IUC B;  2IUC A;  4FDI A;  1K7H A;  4LRD A;  2W5X A;  3SZZ A;  3IGY B;  3E2D A;  1ALJ A;  3WBH A;  5DLW A;  4LRB A;  1AUK A;  5DLV A;  3Q3Q A;  4CYS A;  1Y7A A;  2W5V A;  1O99 A;  3BDH A;  3DYC A;  1EW2 A;  3NKM A;  4UPH A;  4LR2 A;  5L0K A;  2GSU A;  1ZEB A;  3NKR A;  5K4P A;  4TN0 A;  1ALH A;  4CXU A;  4ZG9 A;  4CYR A;  4GTX A;  5KXA A;  3A52 A;  1E3C P;  4UOO A;  4ZG7 A;  4LRA A;  1ANI A;  4UOR A;  3WAY A;  2VQR A;  1AJC A;  2W8S A;  1SHN A;  2XR9 A;  3DPC A;  4N7T A;  1EQJ A;  3M7V A;  2GA3 A;  5GOV A;  5AJ9 A;  1EI6 A;  4FDJ A;  1HDH A;  3TWZ A;  4LQY A;  1EW8 A;  3KD8 A;  3WAV A;  4CXS A;  3T02 A;  4LR8 A;  4UPI A;  1KHJ A;  5IJQ A;  3WAW A;  5LRM A;  1ANJ A;  1HJK A;  2XRG A;  3T01 A;  2ZKT A;  1E1Z P;  5EGH A;  1ZED A;  3CMR A;  5LRN A;  3M8Z A;  3M8W A;  4GTW A;  3BDF A;  4GTY A;  5IJS A;  1AJD A;  1EW9 A;  2QZU A;  1ALI A;  4LR7 A;  3NKP A;  4YR1 A;  5DLT A;  4KAY A;  5EGE A;  3UN5 A;  1KH7 A;  3TG0 A;  2W5S A;  2D1G A;  4ZGA A;  5L0B A;  3ED4 A;  3NVL A;  4LRE A;  1URB A;  1N2L A;  3IGZ B;  4B56 A;  4UPL A;  5GRR A;  1URA A;  5HRT A;  5C66 A;  1ALK A;  3BDG A;  1ED9 A;  4UOP A;  2W8D A;  4MIV A;  3UN2 A;  1AJA A;  1KHL A;  1KHK A;  1ZEF A;  1KH5 A;  2IFY A;  3SZY A;  3M8Y A;  3TX0 A;  4KJG A;  1KH9 A;  4MHX A;  1Y6V A;  4LRF A;  2G9Y A;  1ELX A;  1ELZ A;  2X98 A;  5LIA A;  3UNY A;  2RH6 A;  4NWX A;  1AJB A;  2GSN A;  3MK1 A; 
#chains in the Genus database with same CATH homology
 1B8J A;  3IDD A;  1SHQ A;  1ELY A;  1FSU A;  3WAX A;  4MY4 A;  1KHN A;  5TJ3 A;  1EJJ A;  2GLQ A;  4KJD A;  2GSO A;  5L0E A;  1E33 P;  1N2K A;  3MK0 A;  4LRC A;  4ZG6 A;  2W5W A;  2ANH A;  1O98 A;  4UPK A;  3MK2 A;  3UN3 A;  2W5Q A;  4CXK A;  5LQQ A;  4QAX A;  3OT9 A;  4KAV A;  1E2S P;  1KH4 A;  3NKQ A;  4NWJ A;  5INH A;  3UO0 A;  4GTZ A;  1ED8 A;  3NKO A;  2W5T A;  3BDG B;  2W5R A;  3T00 A;  4LR9 A;  3B5Q A;  1P49 A;  3NKN A;  4KM4 A;  3LXQ A;  1HQA A;  2IUC B;  2IUC A;  4FDI A;  1K7H A;  4LRD A;  2W5X A;  3SZZ A;  3IGY B;  3E2D A;  1ALJ A;  3WBH A;  5DLW A;  4LRB A;  1AUK A;  5DLV A;  3Q3Q A;  4CYS A;  1Y7A A;  2W5V A;  1O99 A;  3BDH A;  3DYC A;  1EW2 A;  3NKM A;  4UPH A;  4LR2 A;  5L0K A;  2GSU A;  1ZEB A;  3NKR A;  5K4P A;  4TN0 A;  1ALH A;  4CXU A;  4ZG9 A;  4CYR A;  4GTX A;  5KXA A;  3A52 A;  1E3C P;  4UOO A;  4ZG7 A;  4LRA A;  1ANI A;  4UOR A;  3WAY A;  2VQR A;  1AJC A;  2W8S A;  1SHN A;  2XR9 A;  3DPC A;  4N7T A;  1EQJ A;  3M7V A;  2GA3 A;  5GOV A;  5AJ9 A;  1EI6 A;  4FDJ A;  1HDH A;  3TWZ A;  4LQY A;  1EW8 A;  3KD8 A;  3WAV A;  4CXS A;  3T02 A;  4LR8 A;  4UPI A;  1KHJ A;  5IJQ A;  3WAW A;  5LRM A;  1ANJ A;  1HJK A;  2XRG A;  3T01 A;  2ZKT A;  1E1Z P;  5EGH A;  1ZED A;  3CMR A;  5LRN A;  3M8Z A;  3M8W A;  4GTW A;  3BDF A;  4GTY A;  5IJS A;  1AJD A;  1EW9 A;  2QZU A;  1ALI A;  4LR7 A;  3NKP A;  4YR1 A;  5DLT A;  4KAY A;  5EGE A;  3UN5 A;  1KH7 A;  3TG0 A;  2W5S A;  2D1G A;  4ZGA A;  5L0B A;  3ED4 A;  3NVL A;  4LRE A;  1URB A;  1N2L A;  3IGZ B;  4B56 A;  4UPL A;  5GRR A;  1URA A;  5HRT A;  5C66 A;  1ALK A;  3BDG A;  1ED9 A;  4UOP A;  2W8D A;  4MIV A;  3UN2 A;  1AJA A;  1KHL A;  1KHK A;  1ZEF A;  1KH5 A;  2IFY A;  3SZY A;  3M8Y A;  3TX0 A;  4KJG A;  1KH9 A;  4MHX A;  1Y6V A;  4LRF A;  2G9Y A;  1ELX A;  1ELZ A;  2X98 A;  5LIA A;  3UNY A;  2RH6 A;  4NWX A;  1AJB A;  2GSN A;  3MK1 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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