2D1GA

Structure of francisella tularensis acid phosphatase a (acpa) bound to orthovanadate
Total Genus 180
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
180
Knots found
sequence length
485
structure length
481
Chain Sequence
NSKPNDYGTLQKLFNNANTLKTTTPIKHVVIIFQENNSFDRYFGMYPNAKNPEGEPKFVAKENTPNVNGLTKQLLENNPNTKNPYRLDRNFQPCSQNHEYHQEISSFNGGLMNKFVEHGGHDNDTYKQNCDGQVMGYYDGNTVTALWNYAQNFALNDNTFGTTFGPSTPGALNLVAGANGPAMSPSGNLENIENNYIIDDPNPYYDDCSYGTSKSGDTNTAVAKITDGYNIGHYLTQKGITWGWFQGGFKPTSYSGKTAICDAMSTNKFGVKSRDYIPHHEPFNYWKETSNPHHLAPSDDKYIGSNDQANHQYDISEFWKALDQNNMPAVSYLKAPGYQDGHGGYSNPLDEQEWLVNTINRIQQSKDWDSTAIIIIYDDSDGDYDHVYSPKSQFSDIKGRQGYGPRLPMLVISPYAKANYVDHSLLNQASVLKFIEYNWGIGSVSKYSNDKYSNNILNMFDFNKEQKTLKLILDPKTGLVM
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structure of Francisella tularensis AcpA: prototype of a unique superfamily of acid phosphatases and phospholipases C
pubmed doi rcsb
source organism Francisella tularensis subsp. novicida
molecule tags Hydrolase
molecule keywords acid phosphatase
total genus 180
structure length 481
sequence length 485
chains with identical sequence B
other databases KnotProt 2.0: S +31
ec nomenclature ec 3.1.3.2: Acid phosphatase.
pdb deposition date 2005-08-20

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF04185 Phosphoesterase Phosphoesterase family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.720.10 Alpha Beta 3-Layer(aba) Sandwich Alkaline Phosphatase, subunit A Alkaline Phosphatase, subunit A 2d1gA02
2W8SA 4FDJA 1ZEDA 1KHKA 3MK0A 2GA3A 1B8JA 3IDDA 4LR8A 2ANHA 1ZEBA 1HQAA 2QZUA 2ZKTA 1AJAA 3M8ZA 1Y6VA 3BDFA 3Q3QA 1KH5A 4GTYA 5DLVA 5TJ3A 1E2SP 5LIAA 1KH7A 3WAXA 4LRBA 3KD8A 4UORA 3WAWA 2W5QA 2GLQA 4ZG7A 4ZGAA 1SHQA 5EGHA 2IFYA 1ANJA 2GSNA 2XRGA 5GOVA 5L0EA 1EW2A 1EI6A 3UN3A 1URAA 4KAYA 1ALKA 3NKRA 1ELYA 1KH9A 3BDGA 4MIVA 5HRTA 4LR9A 4NWXA 3UN2A 3IGYB 3UO0A 4LRCA 1ALHA 1ELZA 3E2DA 3WAVA 4FDIA 4LQYA 4TN0A 4CXUA 4GTWA 1URBA 4ZG9A 1N2LA 2VQRA 3T01A 5LRNA 3TG0A 1ANIA 3WAYA 4UPLA 1EJJA 4NWJA 1ALJA 3TX0A 4CXSA 3M7VA 5DLWA 4LRFA 1KHNA 1E33P 1O99A 3ED4A 3SZZA 4CYSA 2IUCB 4UPIA 3NKOA 5EGEA 5IJSA 2X98A 1AJDA 3NKNA 2G9YA 4KJDA 4YR1A 5INHA 1SHNA 2W5XA 4MY4A 1ED8A 3UNYA 1HDHA 1ELXA 4KJGA 4KM4A 3T00A 5L0BA 1AUKA 1P49A 2D1GA 2W5TA 4LR2A 1Y7AA 4UPKA 1KH4A 1ZEFA 4CXKA 4KAVA 5K4PA 5DLTA 4B56A 5LRMA 2GSUA 3DPCA 1FSUA 2XR9A 2IUCA 1E1ZP 1AJCA 4GTZA 3M8YA 1KHLA 3SZYA 1ALIA 3MK2A 4UOOA 2W8DA 4QAXA 5IJQA 3NKMA 4LREA 1KHJA 3CMRA 3UN5A 3MK1A 1HJKA 1K7HA 2W5SA 2RH6A 4GTXA 3BDHA 3WBHA 5AJ9A 2GSOA 1ED9A 3NVLA 4LRAA 1EW9A 4CYRA 4ZG6A 3DYCA 3NKQA 3LXQA 5C66A 5GRRA 2W5VA 5LQQA 1EQJA 4UOPA 3OT9A 3TWZA 2W5RA 3M8WA 1AJBA 5KXAA 5L0KA 3T02A 4LR7A 1O98A 3IGZB 4UPHA 3NKPA 3A52A 1N2KA 4LRDA 2W5WA 3BDGB 3B5QA 1EW8A 4MHXA 1E3CP 4N7TA
chains in the Genus database with same CATH superfamily
2W8SA 4FDJA 1ZEDA 1KHKA 3MK0A 2GA3A 1B8JA 3IDDA 4LR8A 2ANHA 1ZEBA 1HQAA 2QZUA 2ZKTA 1AJAA 3M8ZA 1Y6VA 3BDFA 3Q3QA 1KH5A 4GTYA 5DLVA 5TJ3A 1E2SP 5LIAA 1KH7A 3WAXA 4LRBA 3KD8A 4UORA 3WAWA 2W5QA 2GLQA 4ZG7A 4ZGAA 1SHQA 5EGHA 2IFYA 1ANJA 2GSNA 2XRGA 5GOVA 5L0EA 1EW2A 1EI6A 3UN3A 1URAA 4KAYA 1ALKA 3NKRA 1ELYA 1KH9A 3BDGA 4MIVA 5HRTA 4LR9A 4NWXA 3UN2A 3IGYB 3UO0A 4LRCA 1ALHA 1ELZA 3E2DA 3WAVA 4FDIA 4LQYA 4TN0A 4CXUA 4GTWA 1URBA 4ZG9A 1N2LA 2VQRA 3T01A 5LRNA 3TG0A 1ANIA 3WAYA 4UPLA 1EJJA 4NWJA 1ALJA 3TX0A 4CXSA 3M7VA 5DLWA 4LRFA 1KHNA 1E33P 1O99A 3ED4A 3SZZA 4CYSA 2IUCB 4UPIA 3NKOA 5EGEA 5IJSA 2X98A 1AJDA 3NKNA 2G9YA 4KJDA 4YR1A 5INHA 1SHNA 2W5XA 4MY4A 1ED8A 3UNYA 1HDHA 1ELXA 4KJGA 4KM4A 3T00A 5L0BA 1AUKA 1P49A 2D1GA 2W5TA 4LR2A 1Y7AA 4UPKA 1KH4A 1ZEFA 4CXKA 4KAVA 5K4PA 5DLTA 4B56A 5LRMA 2GSUA 3DPCA 1FSUA 2XR9A 2IUCA 1E1ZP 1AJCA 4GTZA 3M8YA 1KHLA 3SZYA 1ALIA 3MK2A 4UOOA 2W8DA 4QAXA 5IJQA 3NKMA 4LREA 1KHJA 3CMRA 3UN5A 3MK1A 1HJKA 1K7HA 2W5SA 2RH6A 4GTXA 3BDHA 3WBHA 5AJ9A 2GSOA 1ED9A 3NVLA 4LRAA 1EW9A 4CYRA 4ZG6A 3DYCA 3NKQA 3LXQA 5C66A 5GRRA 2W5VA 5LQQA 1EQJA 4UOPA 3OT9A 3TWZA 2W5RA 3M8WA 1AJBA 5KXAA 5L0KA 3T02A 4LR7A 1O98A 3IGZB 4UPHA 3NKPA 3A52A 1N2KA 4LRDA 2W5WA 3BDGB 3B5QA 1EW8A 4MHXA 1E3CP 4N7TA
chains in the Genus database with same CATH topology
2W8SA 4FDJA 1ZEDA 1KHKA 3MK0A 2GA3A 1B8JA 3IDDA 4LR8A 2ANHA 1ZEBA 1HQAA 2QZUA 2ZKTA 1AJAA 3M8ZA 1Y6VA 3BDFA 3Q3QA 1KH5A 4GTYA 5DLVA 5TJ3A 1E2SP 5LIAA 1KH7A 3WAXA 4LRBA 3KD8A 4UORA 3WAWA 2W5QA 2GLQA 4ZG7A 4ZGAA 1SHQA 5EGHA 2IFYA 1ANJA 2GSNA 2XRGA 5GOVA 5L0EA 1EW2A 1EI6A 3UN3A 1URAA 4KAYA 1ALKA 3NKRA 1ELYA 1KH9A 3BDGA 4MIVA 5HRTA 4LR9A 4NWXA 3UN2A 3IGYB 3UO0A 4LRCA 1ALHA 1ELZA 3E2DA 3WAVA 4FDIA 4LQYA 4TN0A 4CXUA 4GTWA 1URBA 4ZG9A 1N2LA 2VQRA 3T01A 5LRNA 3TG0A 1ANIA 3WAYA 4UPLA 1EJJA 4NWJA 1ALJA 3TX0A 4CXSA 3M7VA 5DLWA 4LRFA 1KHNA 1E33P 1O99A 3ED4A 3SZZA 4CYSA 2IUCB 4UPIA 3NKOA 5EGEA 5IJSA 2X98A 1AJDA 3NKNA 2G9YA 4KJDA 4YR1A 5INHA 1SHNA 2W5XA 4MY4A 1ED8A 3UNYA 1HDHA 1ELXA 4KJGA 4KM4A 3T00A 5L0BA 1AUKA 1P49A 2D1GA 2W5TA 4LR2A 1Y7AA 4UPKA 1KH4A 1ZEFA 4CXKA 4KAVA 5K4PA 5DLTA 4B56A 5LRMA 2GSUA 3DPCA 1FSUA 2XR9A 2IUCA 1E1ZP 1AJCA 4GTZA 3M8YA 1KHLA 3SZYA 1ALIA 3MK2A 4UOOA 2W8DA 4QAXA 5IJQA 3NKMA 4LREA 1KHJA 3CMRA 3UN5A 3MK1A 1HJKA 1K7HA 2W5SA 2RH6A 4GTXA 3BDHA 3WBHA 5AJ9A 2GSOA 1ED9A 3NVLA 4LRAA 1EW9A 4CYRA 4ZG6A 3DYCA 3NKQA 3LXQA 5C66A 5GRRA 2W5VA 5LQQA 1EQJA 4UOPA 3OT9A 3TWZA 2W5RA 3M8WA 1AJBA 5KXAA 5L0KA 3T02A 4LR7A 1O98A 3IGZB 4UPHA 3NKPA 3A52A 1N2KA 4LRDA 2W5WA 3BDGB 3B5QA 1EW8A 4MHXA 1E3CP 4N7TA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2W8S A;  4FDJ A;  1ZED A;  1KHK A;  3MK0 A;  2GA3 A;  1B8J A;  3IDD A;  4LR8 A;  2ANH A;  1ZEB A;  1HQA A;  2QZU A;  2ZKT A;  1AJA A;  3M8Z A;  1Y6V A;  3BDF A;  3Q3Q A;  1KH5 A;  4GTY A;  5DLV A;  5TJ3 A;  1E2S P;  5LIA A;  1KH7 A;  3WAX A;  4LRB A;  3KD8 A;  4UOR A;  3WAW A;  2W5Q A;  2GLQ A;  4ZG7 A;  4ZGA A;  1SHQ A;  5EGH A;  2IFY A;  1ANJ A;  2GSN A;  2XRG A;  5GOV A;  5L0E A;  1EW2 A;  1EI6 A;  3UN3 A;  1URA A;  4KAY A;  1ALK A;  3NKR A;  1ELY A;  1KH9 A;  3BDG A;  4MIV A;  5HRT A;  4LR9 A;  4NWX A;  3UN2 A;  3IGY B;  3UO0 A;  4LRC A;  1ALH A;  1ELZ A;  3E2D A;  3WAV A;  4FDI A;  4LQY A;  4TN0 A;  4CXU A;  4GTW A;  1URB A;  4ZG9 A;  1N2L A;  2VQR A;  3T01 A;  5LRN A;  3TG0 A;  1ANI A;  3WAY A;  4UPL A;  1EJJ A;  4NWJ A;  1ALJ A;  3TX0 A;  4CXS A;  3M7V A;  5DLW A;  4LRF A;  1KHN A;  1E33 P;  1O99 A;  3ED4 A;  3SZZ A;  4CYS A;  2IUC B;  4UPI A;  3NKO A;  5EGE A;  5IJS A;  2X98 A;  1AJD A;  3NKN A;  2G9Y A;  4KJD A;  4YR1 A;  5INH A;  1SHN A;  2W5X A;  4MY4 A;  1ED8 A;  3UNY A;  1HDH A;  1ELX A;  4KJG A;  4KM4 A;  3T00 A;  5L0B A;  1AUK A;  1P49 A;  2D1G A;  2W5T A;  4LR2 A;  1Y7A A;  4UPK A;  1KH4 A;  1ZEF A;  4CXK A;  4KAV A;  5K4P A;  5DLT A;  4B56 A;  5LRM A;  2GSU A;  3DPC A;  1FSU A;  2XR9 A;  2IUC A;  1E1Z P;  1AJC A;  4GTZ A;  3M8Y A;  1KHL A;  3SZY A;  1ALI A;  3MK2 A;  4UOO A;  2W8D A;  4QAX A;  5IJQ A;  3NKM A;  4LRE A;  1KHJ A;  3CMR A;  3UN5 A;  3MK1 A;  1HJK A;  1K7H A;  2W5S A;  2RH6 A;  4GTX A;  3BDH A;  3WBH A;  5AJ9 A;  2GSO A;  1ED9 A;  3NVL A;  4LRA A;  1EW9 A;  4CYR A;  4ZG6 A;  3DYC A;  3NKQ A;  3LXQ A;  5C66 A;  5GRR A;  2W5V A;  5LQQ A;  1EQJ A;  4UOP A;  3OT9 A;  3TWZ A;  2W5R A;  3M8W A;  1AJB A;  5KXA A;  5L0K A;  3T02 A;  4LR7 A;  1O98 A;  3IGZ B;  4UPH A;  3NKP A;  3A52 A;  1N2K A;  4LRD A;  2W5W A;  3BDG B;  3B5Q A;  1EW8 A;  4MHX A;  1E3C P;  4N7T A; 
#chains in the Genus database with same CATH topology
 2W8S A;  4FDJ A;  1ZED A;  1KHK A;  3MK0 A;  2GA3 A;  1B8J A;  3IDD A;  4LR8 A;  2ANH A;  1ZEB A;  1HQA A;  2QZU A;  2ZKT A;  1AJA A;  3M8Z A;  1Y6V A;  3BDF A;  3Q3Q A;  1KH5 A;  4GTY A;  5DLV A;  5TJ3 A;  1E2S P;  5LIA A;  1KH7 A;  3WAX A;  4LRB A;  3KD8 A;  4UOR A;  3WAW A;  2W5Q A;  2GLQ A;  4ZG7 A;  4ZGA A;  1SHQ A;  5EGH A;  2IFY A;  1ANJ A;  2GSN A;  2XRG A;  5GOV A;  5L0E A;  1EW2 A;  1EI6 A;  3UN3 A;  1URA A;  4KAY A;  1ALK A;  3NKR A;  1ELY A;  1KH9 A;  3BDG A;  4MIV A;  5HRT A;  4LR9 A;  4NWX A;  3UN2 A;  3IGY B;  3UO0 A;  4LRC A;  1ALH A;  1ELZ A;  3E2D A;  3WAV A;  4FDI A;  4LQY A;  4TN0 A;  4CXU A;  4GTW A;  1URB A;  4ZG9 A;  1N2L A;  2VQR A;  3T01 A;  5LRN A;  3TG0 A;  1ANI A;  3WAY A;  4UPL A;  1EJJ A;  4NWJ A;  1ALJ A;  3TX0 A;  4CXS A;  3M7V A;  5DLW A;  4LRF A;  1KHN A;  1E33 P;  1O99 A;  3ED4 A;  3SZZ A;  4CYS A;  2IUC B;  4UPI A;  3NKO A;  5EGE A;  5IJS A;  2X98 A;  1AJD A;  3NKN A;  2G9Y A;  4KJD A;  4YR1 A;  5INH A;  1SHN A;  2W5X A;  4MY4 A;  1ED8 A;  3UNY A;  1HDH A;  1ELX A;  4KJG A;  4KM4 A;  3T00 A;  5L0B A;  1AUK A;  1P49 A;  2D1G A;  2W5T A;  4LR2 A;  1Y7A A;  4UPK A;  1KH4 A;  1ZEF A;  4CXK A;  4KAV A;  5K4P A;  5DLT A;  4B56 A;  5LRM A;  2GSU A;  3DPC A;  1FSU A;  2XR9 A;  2IUC A;  1E1Z P;  1AJC A;  4GTZ A;  3M8Y A;  1KHL A;  3SZY A;  1ALI A;  3MK2 A;  4UOO A;  2W8D A;  4QAX A;  5IJQ A;  3NKM A;  4LRE A;  1KHJ A;  3CMR A;  3UN5 A;  3MK1 A;  1HJK A;  1K7H A;  2W5S A;  2RH6 A;  4GTX A;  3BDH A;  3WBH A;  5AJ9 A;  2GSO A;  1ED9 A;  3NVL A;  4LRA A;  1EW9 A;  4CYR A;  4ZG6 A;  3DYC A;  3NKQ A;  3LXQ A;  5C66 A;  5GRR A;  2W5V A;  5LQQ A;  1EQJ A;  4UOP A;  3OT9 A;  3TWZ A;  2W5R A;  3M8W A;  1AJB A;  5KXA A;  5L0K A;  3T02 A;  4LR7 A;  1O98 A;  3IGZ B;  4UPH A;  3NKP A;  3A52 A;  1N2K A;  4LRD A;  2W5W A;  3BDG B;  3B5Q A;  1EW8 A;  4MHX A;  1E3C P;  4N7T A; 
#chains in the Genus database with same CATH homology
 2W8S A;  4FDJ A;  1ZED A;  1KHK A;  3MK0 A;  2GA3 A;  1B8J A;  3IDD A;  4LR8 A;  2ANH A;  1ZEB A;  1HQA A;  2QZU A;  2ZKT A;  1AJA A;  3M8Z A;  1Y6V A;  3BDF A;  3Q3Q A;  1KH5 A;  4GTY A;  5DLV A;  5TJ3 A;  1E2S P;  5LIA A;  1KH7 A;  3WAX A;  4LRB A;  3KD8 A;  4UOR A;  3WAW A;  2W5Q A;  2GLQ A;  4ZG7 A;  4ZGA A;  1SHQ A;  5EGH A;  2IFY A;  1ANJ A;  2GSN A;  2XRG A;  5GOV A;  5L0E A;  1EW2 A;  1EI6 A;  3UN3 A;  1URA A;  4KAY A;  1ALK A;  3NKR A;  1ELY A;  1KH9 A;  3BDG A;  4MIV A;  5HRT A;  4LR9 A;  4NWX A;  3UN2 A;  3IGY B;  3UO0 A;  4LRC A;  1ALH A;  1ELZ A;  3E2D A;  3WAV A;  4FDI A;  4LQY A;  4TN0 A;  4CXU A;  4GTW A;  1URB A;  4ZG9 A;  1N2L A;  2VQR A;  3T01 A;  5LRN A;  3TG0 A;  1ANI A;  3WAY A;  4UPL A;  1EJJ A;  4NWJ A;  1ALJ A;  3TX0 A;  4CXS A;  3M7V A;  5DLW A;  4LRF A;  1KHN A;  1E33 P;  1O99 A;  3ED4 A;  3SZZ A;  4CYS A;  2IUC B;  4UPI A;  3NKO A;  5EGE A;  5IJS A;  2X98 A;  1AJD A;  3NKN A;  2G9Y A;  4KJD A;  4YR1 A;  5INH A;  1SHN A;  2W5X A;  4MY4 A;  1ED8 A;  3UNY A;  1HDH A;  1ELX A;  4KJG A;  4KM4 A;  3T00 A;  5L0B A;  1AUK A;  1P49 A;  2D1G A;  2W5T A;  4LR2 A;  1Y7A A;  4UPK A;  1KH4 A;  1ZEF A;  4CXK A;  4KAV A;  5K4P A;  5DLT A;  4B56 A;  5LRM A;  2GSU A;  3DPC A;  1FSU A;  2XR9 A;  2IUC A;  1E1Z P;  1AJC A;  4GTZ A;  3M8Y A;  1KHL A;  3SZY A;  1ALI A;  3MK2 A;  4UOO A;  2W8D A;  4QAX A;  5IJQ A;  3NKM A;  4LRE A;  1KHJ A;  3CMR A;  3UN5 A;  3MK1 A;  1HJK A;  1K7H A;  2W5S A;  2RH6 A;  4GTX A;  3BDH A;  3WBH A;  5AJ9 A;  2GSO A;  1ED9 A;  3NVL A;  4LRA A;  1EW9 A;  4CYR A;  4ZG6 A;  3DYC A;  3NKQ A;  3LXQ A;  5C66 A;  5GRR A;  2W5V A;  5LQQ A;  1EQJ A;  4UOP A;  3OT9 A;  3TWZ A;  2W5R A;  3M8W A;  1AJB A;  5KXA A;  5L0K A;  3T02 A;  4LR7 A;  1O98 A;  3IGZ B;  4UPH A;  3NKP A;  3A52 A;  1N2K A;  4LRD A;  2W5W A;  3BDG B;  3B5Q A;  1EW8 A;  4MHX A;  1E3C P;  4N7T A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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