2D1GA

Structure of francisella tularensis acid phosphatase a (acpa) bound to orthovanadate
Total Genus 180
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
180
Knots found
sequence length
485
structure length
481
Chain Sequence
b'NSKPNDYGTLQKLFNNANTLKTTTPIKHVVIIFQENNSFDRYFGMYPNAKNPEGEPKFVAKENTPNVNGLTKQLLENNPNTKNPYRLDRNFQPCSQNHEYHQEISSFNGGLMNKFVEHGGHDNDTYKQNCDGQVMGYYDGNTVTALWNYAQNFALNDNTFGTTFGPSTPGALNLVAGANGPAMSPSGNLENIENNYIIDDPNPYYDDCSYGTSKSGDTNTAVAKITDGYNIGHYLTQKGITWGWFQGGFKPTSYSGKTAICDAMSTNKFGVKSRDYIPHHEPFNYWKETSNPHHLAPSDDKYIGSNDQANHQYDISEFWKALDQNNMPAVSYLKAPGYQDGHGGYSNPLDEQEWLVNTINRIQQSKDWDSTAIIIIYDDSDGDYDHVYSPKSQFSDIKGRQGYGPRLPMLVISPYAKANYVDHSLLNQASVLKFIEYNWGIGSVSKYSNDKYSNNILNMFDFNKEQKTLKLILDPKTGLVM'
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule keywords acid phosphatase
publication title Structure of Francisella tularensis AcpA: prototype of a unique superfamily of acid phosphatases and phospholipases C
pubmed doi rcsb
source organism Francisella tularensis subsp. novicida
molecule tags Hydrolase
total genus 180
structure length 481
sequence length 485
chains with identical sequence B
other databases KnotProt 2.0: S +31
ec nomenclature ec 3.1.3.2: Acid phosphatase.
pdb deposition date 2005-08-20

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF04185 Phosphoesterase Phosphoesterase family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.720.10 Alpha Beta 3-Layer(aba) Sandwich Alkaline Phosphatase, subunit A Alkaline Phosphatase, subunit A 2d1gA02
1URAA 3NKMA 3SZZA 5TJ3A 1KH7A 3A52A 4UORA 3SZYA 1KH5A 4UPLA 1E33P 5IJQA 4KAYA 3NKOA 1AUKA 3CMRA 4LR7A 4LR9A 4CYSA 1AJAA 3KD8A 3TWZA 5GOVA 1P49A 4UOOA 1KHKA 1ZEDA 1ZEBA 5AJ9A 5KXAA 1O98A 3BDHA 4GTWA 4QAXA 1ELYA 5LIAA 2GSNA 4KJGA 3UN2A 3E2DA 2W5RA 4LRBA 2W5WA 1Y7AA 4UOPA 5K4PA 4KJDA 3UNYA 2GSUA 4FDJA 3WAVA 1AJBA 3IDDA 2XR9A 4ZG9A 1FSUA 1KH4A 4ZG7A 4FDIA 4LQYA 1E3CP 2W5VA 3T01A 1ELZA 1N2KA 3MK0A 1B8JA 3OT9A 2W8SA 1EI6A 4MIVA 1ED9A 1EW2A 1N2LA 3NKRA 4KAVA 5L0EA 2W5TA 1URBA 4ZGAA 3B5QA 4MHXA 4ZG6A 3BDGB 1Y6VA 4NWXA 2D1GA 1ZEFA 3MK2A 1KHJA 5L0BA 5LQQA 4LREA 2W8DA 4TN0A 4YR1A 4LRFA 4MY4A 4UPHA 5LRMA 3MK1A 4GTZA 5INHA 5L0KA 3NKNA 3T02A 1ALKA 4NWJA 3BDGA 1E2SP 3TX0A 3DYCA 2X98A 1HDHA 1AJDA 5GRRA 1SHNA 1EJJA 1O99A 1KHNA 1K7HA 4LRDA 4KM4A 1ANJA 2IUCB 2GA3A 1SHQA 4CXUA 1ANIA 3UN5A 5EGEA 3T00A 5DLWA 4CYRA 3UN3A 5LRNA 2IUCA 1EQJA 2VQRA 3Q3QA 3M8ZA 5IJSA 4B56A 1KH9A 3IGYB 4CXSA 1HQAA 5HRTA 3NKQA 4UPKA 1ELXA 2XRGA 5DLTA 3WBHA 3WAYA 1ALHA 3LXQA 1ALIA 1ED8A 4GTXA 5DLVA 1E1ZP 1EW9A 3M8WA 2IFYA 1EW8A 4LR2A 4CXKA 1KHLA 3M8YA 3BDFA 2G9YA 5EGHA 2GSOA 3M7VA 3WAXA 2RH6A 4N7TA 5C66A 1ALJA 2W5QA 2W5XA 3NVLA 4GTYA 2QZUA 3ED4A 2W5SA 2ZKTA 3NKPA 4LR8A 2GLQA 3UO0A 2ANHA 3DPCA 3TG0A 1AJCA 1HJKA 4UPIA 3IGZB 4LRCA 3WAWA 4LRAA
chains in the Genus database with same CATH superfamily
1URAA 3NKMA 3SZZA 5TJ3A 1KH7A 3A52A 4UORA 3SZYA 1KH5A 4UPLA 1E33P 5IJQA 4KAYA 3NKOA 1AUKA 3CMRA 4LR7A 4LR9A 4CYSA 1AJAA 3KD8A 3TWZA 5GOVA 1P49A 4UOOA 1KHKA 1ZEDA 1ZEBA 5AJ9A 5KXAA 1O98A 3BDHA 4GTWA 4QAXA 1ELYA 5LIAA 2GSNA 4KJGA 3UN2A 3E2DA 2W5RA 4LRBA 2W5WA 1Y7AA 4UOPA 5K4PA 4KJDA 3UNYA 2GSUA 4FDJA 3WAVA 1AJBA 3IDDA 2XR9A 4ZG9A 1FSUA 1KH4A 4ZG7A 4FDIA 4LQYA 1E3CP 2W5VA 3T01A 1ELZA 1N2KA 3MK0A 1B8JA 3OT9A 2W8SA 1EI6A 4MIVA 1ED9A 1EW2A 1N2LA 3NKRA 4KAVA 5L0EA 2W5TA 1URBA 4ZGAA 3B5QA 4MHXA 4ZG6A 3BDGB 1Y6VA 4NWXA 2D1GA 1ZEFA 3MK2A 1KHJA 5L0BA 5LQQA 4LREA 2W8DA 4TN0A 4YR1A 4LRFA 4MY4A 4UPHA 5LRMA 3MK1A 4GTZA 5INHA 5L0KA 3NKNA 3T02A 1ALKA 4NWJA 3BDGA 1E2SP 3TX0A 3DYCA 2X98A 1HDHA 1AJDA 5GRRA 1SHNA 1EJJA 1O99A 1KHNA 1K7HA 4LRDA 4KM4A 1ANJA 2IUCB 2GA3A 1SHQA 4CXUA 1ANIA 3UN5A 5EGEA 3T00A 5DLWA 4CYRA 3UN3A 5LRNA 2IUCA 1EQJA 2VQRA 3Q3QA 3M8ZA 5IJSA 4B56A 1KH9A 3IGYB 4CXSA 1HQAA 5HRTA 3NKQA 4UPKA 1ELXA 2XRGA 5DLTA 3WBHA 3WAYA 1ALHA 3LXQA 1ALIA 1ED8A 4GTXA 5DLVA 1E1ZP 1EW9A 3M8WA 2IFYA 1EW8A 4LR2A 4CXKA 1KHLA 3M8YA 3BDFA 2G9YA 5EGHA 2GSOA 3M7VA 3WAXA 2RH6A 4N7TA 5C66A 1ALJA 2W5QA 2W5XA 3NVLA 4GTYA 2QZUA 3ED4A 2W5SA 2ZKTA 3NKPA 4LR8A 2GLQA 3UO0A 2ANHA 3DPCA 3TG0A 1AJCA 1HJKA 4UPIA 3IGZB 4LRCA 3WAWA 4LRAA
chains in the Genus database with same CATH topology
1URAA 3NKMA 3SZZA 5TJ3A 1KH7A 3A52A 4UORA 3SZYA 1KH5A 4UPLA 1E33P 5IJQA 4KAYA 3NKOA 1AUKA 3CMRA 4LR7A 4LR9A 4CYSA 1AJAA 3KD8A 3TWZA 5GOVA 1P49A 4UOOA 1KHKA 1ZEDA 1ZEBA 5AJ9A 5KXAA 1O98A 3BDHA 4GTWA 4QAXA 1ELYA 5LIAA 2GSNA 4KJGA 3UN2A 3E2DA 2W5RA 4LRBA 2W5WA 1Y7AA 4UOPA 5K4PA 4KJDA 3UNYA 2GSUA 4FDJA 3WAVA 1AJBA 3IDDA 2XR9A 4ZG9A 1FSUA 1KH4A 4ZG7A 4FDIA 4LQYA 1E3CP 2W5VA 3T01A 1ELZA 1N2KA 3MK0A 1B8JA 3OT9A 2W8SA 1EI6A 4MIVA 1ED9A 1EW2A 1N2LA 3NKRA 4KAVA 5L0EA 2W5TA 1URBA 4ZGAA 3B5QA 4MHXA 4ZG6A 3BDGB 1Y6VA 4NWXA 2D1GA 1ZEFA 3MK2A 1KHJA 5L0BA 5LQQA 4LREA 2W8DA 4TN0A 4YR1A 4LRFA 4MY4A 4UPHA 5LRMA 3MK1A 4GTZA 5INHA 5L0KA 3NKNA 3T02A 1ALKA 4NWJA 3BDGA 1E2SP 3TX0A 3DYCA 2X98A 1HDHA 1AJDA 5GRRA 1SHNA 1EJJA 1O99A 1KHNA 1K7HA 4LRDA 4KM4A 1ANJA 2IUCB 2GA3A 1SHQA 4CXUA 1ANIA 3UN5A 5EGEA 3T00A 5DLWA 4CYRA 3UN3A 5LRNA 2IUCA 1EQJA 2VQRA 3Q3QA 3M8ZA 5IJSA 4B56A 1KH9A 3IGYB 4CXSA 1HQAA 5HRTA 3NKQA 4UPKA 1ELXA 2XRGA 5DLTA 3WBHA 3WAYA 1ALHA 3LXQA 1ALIA 1ED8A 4GTXA 5DLVA 1E1ZP 1EW9A 3M8WA 2IFYA 1EW8A 4LR2A 4CXKA 1KHLA 3M8YA 3BDFA 2G9YA 5EGHA 2GSOA 3M7VA 3WAXA 2RH6A 4N7TA 5C66A 1ALJA 2W5QA 2W5XA 3NVLA 4GTYA 2QZUA 3ED4A 2W5SA 2ZKTA 3NKPA 4LR8A 2GLQA 3UO0A 2ANHA 3DPCA 3TG0A 1AJCA 1HJKA 4UPIA 3IGZB 4LRCA 3WAWA 4LRAA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1URA A;  3NKM A;  3SZZ A;  5TJ3 A;  1KH7 A;  3A52 A;  4UOR A;  3SZY A;  1KH5 A;  4UPL A;  1E33 P;  5IJQ A;  4KAY A;  3NKO A;  1AUK A;  3CMR A;  4LR7 A;  4LR9 A;  4CYS A;  1AJA A;  3KD8 A;  3TWZ A;  5GOV A;  1P49 A;  4UOO A;  1KHK A;  1ZED A;  1ZEB A;  5AJ9 A;  5KXA A;  1O98 A;  3BDH A;  4GTW A;  4QAX A;  1ELY A;  5LIA A;  2GSN A;  4KJG A;  3UN2 A;  3E2D A;  2W5R A;  4LRB A;  2W5W A;  1Y7A A;  4UOP A;  5K4P A;  4KJD A;  3UNY A;  2GSU A;  4FDJ A;  3WAV A;  1AJB A;  3IDD A;  2XR9 A;  4ZG9 A;  1FSU A;  1KH4 A;  4ZG7 A;  4FDI A;  4LQY A;  1E3C P;  2W5V A;  3T01 A;  1ELZ A;  1N2K A;  3MK0 A;  1B8J A;  3OT9 A;  2W8S A;  1EI6 A;  4MIV A;  1ED9 A;  1EW2 A;  1N2L A;  3NKR A;  4KAV A;  5L0E A;  2W5T A;  1URB A;  4ZGA A;  3B5Q A;  4MHX A;  4ZG6 A;  3BDG B;  1Y6V A;  4NWX A;  2D1G A;  1ZEF A;  3MK2 A;  1KHJ A;  5L0B A;  5LQQ A;  4LRE A;  2W8D A;  4TN0 A;  4YR1 A;  4LRF A;  4MY4 A;  4UPH A;  5LRM A;  3MK1 A;  4GTZ A;  5INH A;  5L0K A;  3NKN A;  3T02 A;  1ALK A;  4NWJ A;  3BDG A;  1E2S P;  3TX0 A;  3DYC A;  2X98 A;  1HDH A;  1AJD A;  5GRR A;  1SHN A;  1EJJ A;  1O99 A;  1KHN A;  1K7H A;  4LRD A;  4KM4 A;  1ANJ A;  2IUC B;  2GA3 A;  1SHQ A;  4CXU A;  1ANI A;  3UN5 A;  5EGE A;  3T00 A;  5DLW A;  4CYR A;  3UN3 A;  5LRN A;  2IUC A;  1EQJ A;  2VQR A;  3Q3Q A;  3M8Z A;  5IJS A;  4B56 A;  1KH9 A;  3IGY B;  4CXS A;  1HQA A;  5HRT A;  3NKQ A;  4UPK A;  1ELX A;  2XRG A;  5DLT A;  3WBH A;  3WAY A;  1ALH A;  3LXQ A;  1ALI A;  1ED8 A;  4GTX A;  5DLV A;  1E1Z P;  1EW9 A;  3M8W A;  2IFY A;  1EW8 A;  4LR2 A;  4CXK A;  1KHL A;  3M8Y A;  3BDF A;  2G9Y A;  5EGH A;  2GSO A;  3M7V A;  3WAX A;  2RH6 A;  4N7T A;  5C66 A;  1ALJ A;  2W5Q A;  2W5X A;  3NVL A;  4GTY A;  2QZU A;  3ED4 A;  2W5S A;  2ZKT A;  3NKP A;  4LR8 A;  2GLQ A;  3UO0 A;  2ANH A;  3DPC A;  3TG0 A;  1AJC A;  1HJK A;  4UPI A;  3IGZ B;  4LRC A;  3WAW A;  4LRA A; 
#chains in the Genus database with same CATH topology
 1URA A;  3NKM A;  3SZZ A;  5TJ3 A;  1KH7 A;  3A52 A;  4UOR A;  3SZY A;  1KH5 A;  4UPL A;  1E33 P;  5IJQ A;  4KAY A;  3NKO A;  1AUK A;  3CMR A;  4LR7 A;  4LR9 A;  4CYS A;  1AJA A;  3KD8 A;  3TWZ A;  5GOV A;  1P49 A;  4UOO A;  1KHK A;  1ZED A;  1ZEB A;  5AJ9 A;  5KXA A;  1O98 A;  3BDH A;  4GTW A;  4QAX A;  1ELY A;  5LIA A;  2GSN A;  4KJG A;  3UN2 A;  3E2D A;  2W5R A;  4LRB A;  2W5W A;  1Y7A A;  4UOP A;  5K4P A;  4KJD A;  3UNY A;  2GSU A;  4FDJ A;  3WAV A;  1AJB A;  3IDD A;  2XR9 A;  4ZG9 A;  1FSU A;  1KH4 A;  4ZG7 A;  4FDI A;  4LQY A;  1E3C P;  2W5V A;  3T01 A;  1ELZ A;  1N2K A;  3MK0 A;  1B8J A;  3OT9 A;  2W8S A;  1EI6 A;  4MIV A;  1ED9 A;  1EW2 A;  1N2L A;  3NKR A;  4KAV A;  5L0E A;  2W5T A;  1URB A;  4ZGA A;  3B5Q A;  4MHX A;  4ZG6 A;  3BDG B;  1Y6V A;  4NWX A;  2D1G A;  1ZEF A;  3MK2 A;  1KHJ A;  5L0B A;  5LQQ A;  4LRE A;  2W8D A;  4TN0 A;  4YR1 A;  4LRF A;  4MY4 A;  4UPH A;  5LRM A;  3MK1 A;  4GTZ A;  5INH A;  5L0K A;  3NKN A;  3T02 A;  1ALK A;  4NWJ A;  3BDG A;  1E2S P;  3TX0 A;  3DYC A;  2X98 A;  1HDH A;  1AJD A;  5GRR A;  1SHN A;  1EJJ A;  1O99 A;  1KHN A;  1K7H A;  4LRD A;  4KM4 A;  1ANJ A;  2IUC B;  2GA3 A;  1SHQ A;  4CXU A;  1ANI A;  3UN5 A;  5EGE A;  3T00 A;  5DLW A;  4CYR A;  3UN3 A;  5LRN A;  2IUC A;  1EQJ A;  2VQR A;  3Q3Q A;  3M8Z A;  5IJS A;  4B56 A;  1KH9 A;  3IGY B;  4CXS A;  1HQA A;  5HRT A;  3NKQ A;  4UPK A;  1ELX A;  2XRG A;  5DLT A;  3WBH A;  3WAY A;  1ALH A;  3LXQ A;  1ALI A;  1ED8 A;  4GTX A;  5DLV A;  1E1Z P;  1EW9 A;  3M8W A;  2IFY A;  1EW8 A;  4LR2 A;  4CXK A;  1KHL A;  3M8Y A;  3BDF A;  2G9Y A;  5EGH A;  2GSO A;  3M7V A;  3WAX A;  2RH6 A;  4N7T A;  5C66 A;  1ALJ A;  2W5Q A;  2W5X A;  3NVL A;  4GTY A;  2QZU A;  3ED4 A;  2W5S A;  2ZKT A;  3NKP A;  4LR8 A;  2GLQ A;  3UO0 A;  2ANH A;  3DPC A;  3TG0 A;  1AJC A;  1HJK A;  4UPI A;  3IGZ B;  4LRC A;  3WAW A;  4LRA A; 
#chains in the Genus database with same CATH homology
 1URA A;  3NKM A;  3SZZ A;  5TJ3 A;  1KH7 A;  3A52 A;  4UOR A;  3SZY A;  1KH5 A;  4UPL A;  1E33 P;  5IJQ A;  4KAY A;  3NKO A;  1AUK A;  3CMR A;  4LR7 A;  4LR9 A;  4CYS A;  1AJA A;  3KD8 A;  3TWZ A;  5GOV A;  1P49 A;  4UOO A;  1KHK A;  1ZED A;  1ZEB A;  5AJ9 A;  5KXA A;  1O98 A;  3BDH A;  4GTW A;  4QAX A;  1ELY A;  5LIA A;  2GSN A;  4KJG A;  3UN2 A;  3E2D A;  2W5R A;  4LRB A;  2W5W A;  1Y7A A;  4UOP A;  5K4P A;  4KJD A;  3UNY A;  2GSU A;  4FDJ A;  3WAV A;  1AJB A;  3IDD A;  2XR9 A;  4ZG9 A;  1FSU A;  1KH4 A;  4ZG7 A;  4FDI A;  4LQY A;  1E3C P;  2W5V A;  3T01 A;  1ELZ A;  1N2K A;  3MK0 A;  1B8J A;  3OT9 A;  2W8S A;  1EI6 A;  4MIV A;  1ED9 A;  1EW2 A;  1N2L A;  3NKR A;  4KAV A;  5L0E A;  2W5T A;  1URB A;  4ZGA A;  3B5Q A;  4MHX A;  4ZG6 A;  3BDG B;  1Y6V A;  4NWX A;  2D1G A;  1ZEF A;  3MK2 A;  1KHJ A;  5L0B A;  5LQQ A;  4LRE A;  2W8D A;  4TN0 A;  4YR1 A;  4LRF A;  4MY4 A;  4UPH A;  5LRM A;  3MK1 A;  4GTZ A;  5INH A;  5L0K A;  3NKN A;  3T02 A;  1ALK A;  4NWJ A;  3BDG A;  1E2S P;  3TX0 A;  3DYC A;  2X98 A;  1HDH A;  1AJD A;  5GRR A;  1SHN A;  1EJJ A;  1O99 A;  1KHN A;  1K7H A;  4LRD A;  4KM4 A;  1ANJ A;  2IUC B;  2GA3 A;  1SHQ A;  4CXU A;  1ANI A;  3UN5 A;  5EGE A;  3T00 A;  5DLW A;  4CYR A;  3UN3 A;  5LRN A;  2IUC A;  1EQJ A;  2VQR A;  3Q3Q A;  3M8Z A;  5IJS A;  4B56 A;  1KH9 A;  3IGY B;  4CXS A;  1HQA A;  5HRT A;  3NKQ A;  4UPK A;  1ELX A;  2XRG A;  5DLT A;  3WBH A;  3WAY A;  1ALH A;  3LXQ A;  1ALI A;  1ED8 A;  4GTX A;  5DLV A;  1E1Z P;  1EW9 A;  3M8W A;  2IFY A;  1EW8 A;  4LR2 A;  4CXK A;  1KHL A;  3M8Y A;  3BDF A;  2G9Y A;  5EGH A;  2GSO A;  3M7V A;  3WAX A;  2RH6 A;  4N7T A;  5C66 A;  1ALJ A;  2W5Q A;  2W5X A;  3NVL A;  4GTY A;  2QZU A;  3ED4 A;  2W5S A;  2ZKT A;  3NKP A;  4LR8 A;  2GLQ A;  3UO0 A;  2ANH A;  3DPC A;  3TG0 A;  1AJC A;  1HJK A;  4UPI A;  3IGZ B;  4LRC A;  3WAW A;  4LRA A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...