2D1GA

Structure of francisella tularensis acid phosphatase a (acpa) bound to orthovanadate
Total Genus 180
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
180
Knots found
sequence length
485
structure length
481
Chain Sequence
NSKPNDYGTLQKLFNNANTLKTTTPIKHVVIIFQENNSFDRYFGMYPNAKNPEGEPKFVAKENTPNVNGLTKQLLENNPNTKNPYRLDRNFQPCSQNHEYHQEISSFNGGLMNKFVEHGGHDNDTYKQNCDGQVMGYYDGNTVTALWNYAQNFALNDNTFGTTFGPSTPGALNLVAGANGPAMSPSGNLENIENNYIIDDPNPYYDDCSYGTSKSGDTNTAVAKITDGYNIGHYLTQKGITWGWFQGGFKPTSYSGKTAICDAMSTNKFGVKSRDYIPHHEPFNYWKETSNPHHLAPSDDKYIGSNDQANHQYDISEFWKALDQNNMPAVSYLKAPGYQDGHGGYSNPLDEQEWLVNTINRIQQSKDWDSTAIIIIYDDSDGDYDHVYSPKSQFSDIKGRQGYGPRLPMLVISPYAKANYVDHSLLNQASVLKFIEYNWGIGSVSKYSNDKYSNNILNMFDFNKEQKTLKLILDPKTGLVM
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structure of Francisella tularensis AcpA: prototype of a unique superfamily of acid phosphatases and phospholipases C
pubmed doi rcsb
molecule tags Hydrolase
source organism Francisella tularensis subsp. novicida
molecule keywords acid phosphatase
total genus 180
structure length 481
sequence length 485
chains with identical sequence B
other databases KnotProt 2.0: S +31
ec nomenclature ec 3.1.3.2: Acid phosphatase.
pdb deposition date 2005-08-20

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF04185 Phosphoesterase Phosphoesterase family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.720.10 Alpha Beta 3-Layer(aba) Sandwich Alkaline Phosphatase, subunit A Alkaline Phosphatase, subunit A 2d1gA02
3A52A 4CYSA 3UN3A 1Y6VA 4UOPA 4QAXA 5L0EA 2W5RA 1N2KA 3B5QA 3T00A 1ED8A 4UOOA 4ZGAA 2QZUA 1KH7A 3IDDA 1KH5A 5K4PA 4CXKA 5DLWA 5LRNA 1ANIA 1ZEDA 3M7VA 1B8JA 1ALHA 2XR9A 5AJ9A 1EJJA 1AJDA 4N7TA 1O99A 5TJ3A 1KHLA 2GSOA 4ZG7A 3WAYA 3MK1A 3SZZA 5L0BA 3TWZA 1E1ZP 4LREA 3MK0A 1ELXA 4LQYA 2ANHA 1ALIA 2VQRA 1EI6A 1EW8A 5IJQA 4GTWA 3WAWA 2W8SA 3DPCA 4NWXA 1K7HA 1HQAA 2W5WA 2W8DA 1SHQA 4UPIA 1N2LA 1KHJA 4MY4A 4KAYA 3TG0A 4KJDA 1ED9A 5IJSA 3NKMA 4CXUA 1KH9A 3BDFA 1AJCA 3MK2A 5EGHA 4UPHA 2RH6A 1FSUA 4LR8A 3M8ZA 4GTXA 1URBA 1SHNA 1E2SP 3TX0A 2W5VA 5GRRA 5INHA 4LR7A 4GTZA 4LR2A 5KXAA 1EW2A 3T01A 3WAVA 2ZKTA 1Y7AA 1ALKA 4LRAA 5LRMA 4CYRA 3WAXA 4ZG9A 1P49A 2XRGA 2X98A 1EW9A 2W5SA 1EQJA 4KM4A 4LRFA 1AJAA 1O98A 2IUCB 1ELYA 3NKOA 3BDGA 1ELZA 4YR1A 4UORA 3NVLA 4LRDA 3UN5A 3IGYB 3CMRA 1ANJA 3E2DA 3UNYA 1E3CP 3UN2A 1AJBA 4FDIA 4NWJA 3SZYA 1KHKA 4LR9A 4MIVA 5GOVA 4ZG6A 5C66A 4TN0A 1ZEBA 5L0KA 5DLTA 4CXSA 1AUKA 4LRBA 1KH4A 2GLQA 3KD8A 3LXQA 5EGEA 2GA3A 3NKRA 1HJKA 2W5QA 2D1GA 5LIAA 3M8YA 3NKQA 2GSUA 4UPLA 2IFYA 3NKPA 2GSNA 3ED4A 4LRCA 1HDHA 3M8WA 1E33P 2G9YA 5DLVA 4B56A 5HRTA 4KAVA 4KJGA 3WBHA 1ZEFA 2IUCA 3BDGB 4MHXA 3NKNA 3T02A 2W5TA 4UPKA 5LQQA 3OT9A 1URAA 3BDHA 1ALJA 1KHNA 4FDJA 3UO0A 3Q3QA 3DYCA 4GTYA 3IGZB 2W5XA
chains in the Genus database with same CATH superfamily
3A52A 4CYSA 3UN3A 1Y6VA 4UOPA 4QAXA 5L0EA 2W5RA 1N2KA 3B5QA 3T00A 1ED8A 4UOOA 4ZGAA 2QZUA 1KH7A 3IDDA 1KH5A 5K4PA 4CXKA 5DLWA 5LRNA 1ANIA 1ZEDA 3M7VA 1B8JA 1ALHA 2XR9A 5AJ9A 1EJJA 1AJDA 4N7TA 1O99A 5TJ3A 1KHLA 2GSOA 4ZG7A 3WAYA 3MK1A 3SZZA 5L0BA 3TWZA 1E1ZP 4LREA 3MK0A 1ELXA 4LQYA 2ANHA 1ALIA 2VQRA 1EI6A 1EW8A 5IJQA 4GTWA 3WAWA 2W8SA 3DPCA 4NWXA 1K7HA 1HQAA 2W5WA 2W8DA 1SHQA 4UPIA 1N2LA 1KHJA 4MY4A 4KAYA 3TG0A 4KJDA 1ED9A 5IJSA 3NKMA 4CXUA 1KH9A 3BDFA 1AJCA 3MK2A 5EGHA 4UPHA 2RH6A 1FSUA 4LR8A 3M8ZA 4GTXA 1URBA 1SHNA 1E2SP 3TX0A 2W5VA 5GRRA 5INHA 4LR7A 4GTZA 4LR2A 5KXAA 1EW2A 3T01A 3WAVA 2ZKTA 1Y7AA 1ALKA 4LRAA 5LRMA 4CYRA 3WAXA 4ZG9A 1P49A 2XRGA 2X98A 1EW9A 2W5SA 1EQJA 4KM4A 4LRFA 1AJAA 1O98A 2IUCB 1ELYA 3NKOA 3BDGA 1ELZA 4YR1A 4UORA 3NVLA 4LRDA 3UN5A 3IGYB 3CMRA 1ANJA 3E2DA 3UNYA 1E3CP 3UN2A 1AJBA 4FDIA 4NWJA 3SZYA 1KHKA 4LR9A 4MIVA 5GOVA 4ZG6A 5C66A 4TN0A 1ZEBA 5L0KA 5DLTA 4CXSA 1AUKA 4LRBA 1KH4A 2GLQA 3KD8A 3LXQA 5EGEA 2GA3A 3NKRA 1HJKA 2W5QA 2D1GA 5LIAA 3M8YA 3NKQA 2GSUA 4UPLA 2IFYA 3NKPA 2GSNA 3ED4A 4LRCA 1HDHA 3M8WA 1E33P 2G9YA 5DLVA 4B56A 5HRTA 4KAVA 4KJGA 3WBHA 1ZEFA 2IUCA 3BDGB 4MHXA 3NKNA 3T02A 2W5TA 4UPKA 5LQQA 3OT9A 1URAA 3BDHA 1ALJA 1KHNA 4FDJA 3UO0A 3Q3QA 3DYCA 4GTYA 3IGZB 2W5XA
chains in the Genus database with same CATH topology
3A52A 4CYSA 3UN3A 1Y6VA 4UOPA 4QAXA 5L0EA 2W5RA 1N2KA 3B5QA 3T00A 1ED8A 4UOOA 4ZGAA 2QZUA 1KH7A 3IDDA 1KH5A 5K4PA 4CXKA 5DLWA 5LRNA 1ANIA 1ZEDA 3M7VA 1B8JA 1ALHA 2XR9A 5AJ9A 1EJJA 1AJDA 4N7TA 1O99A 5TJ3A 1KHLA 2GSOA 4ZG7A 3WAYA 3MK1A 3SZZA 5L0BA 3TWZA 1E1ZP 4LREA 3MK0A 1ELXA 4LQYA 2ANHA 1ALIA 2VQRA 1EI6A 1EW8A 5IJQA 4GTWA 3WAWA 2W8SA 3DPCA 4NWXA 1K7HA 1HQAA 2W5WA 2W8DA 1SHQA 4UPIA 1N2LA 1KHJA 4MY4A 4KAYA 3TG0A 4KJDA 1ED9A 5IJSA 3NKMA 4CXUA 1KH9A 3BDFA 1AJCA 3MK2A 5EGHA 4UPHA 2RH6A 1FSUA 4LR8A 3M8ZA 4GTXA 1URBA 1SHNA 1E2SP 3TX0A 2W5VA 5GRRA 5INHA 4LR7A 4GTZA 4LR2A 5KXAA 1EW2A 3T01A 3WAVA 2ZKTA 1Y7AA 1ALKA 4LRAA 5LRMA 4CYRA 3WAXA 4ZG9A 1P49A 2XRGA 2X98A 1EW9A 2W5SA 1EQJA 4KM4A 4LRFA 1AJAA 1O98A 2IUCB 1ELYA 3NKOA 3BDGA 1ELZA 4YR1A 4UORA 3NVLA 4LRDA 3UN5A 3IGYB 3CMRA 1ANJA 3E2DA 3UNYA 1E3CP 3UN2A 1AJBA 4FDIA 4NWJA 3SZYA 1KHKA 4LR9A 4MIVA 5GOVA 4ZG6A 5C66A 4TN0A 1ZEBA 5L0KA 5DLTA 4CXSA 1AUKA 4LRBA 1KH4A 2GLQA 3KD8A 3LXQA 5EGEA 2GA3A 3NKRA 1HJKA 2W5QA 2D1GA 5LIAA 3M8YA 3NKQA 2GSUA 4UPLA 2IFYA 3NKPA 2GSNA 3ED4A 4LRCA 1HDHA 3M8WA 1E33P 2G9YA 5DLVA 4B56A 5HRTA 4KAVA 4KJGA 3WBHA 1ZEFA 2IUCA 3BDGB 4MHXA 3NKNA 3T02A 2W5TA 4UPKA 5LQQA 3OT9A 1URAA 3BDHA 1ALJA 1KHNA 4FDJA 3UO0A 3Q3QA 3DYCA 4GTYA 3IGZB 2W5XA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3A52 A;  4CYS A;  3UN3 A;  1Y6V A;  4UOP A;  4QAX A;  5L0E A;  2W5R A;  1N2K A;  3B5Q A;  3T00 A;  1ED8 A;  4UOO A;  4ZGA A;  2QZU A;  1KH7 A;  3IDD A;  1KH5 A;  5K4P A;  4CXK A;  5DLW A;  5LRN A;  1ANI A;  1ZED A;  3M7V A;  1B8J A;  1ALH A;  2XR9 A;  5AJ9 A;  1EJJ A;  1AJD A;  4N7T A;  1O99 A;  5TJ3 A;  1KHL A;  2GSO A;  4ZG7 A;  3WAY A;  3MK1 A;  3SZZ A;  5L0B A;  3TWZ A;  1E1Z P;  4LRE A;  3MK0 A;  1ELX A;  4LQY A;  2ANH A;  1ALI A;  2VQR A;  1EI6 A;  1EW8 A;  5IJQ A;  4GTW A;  3WAW A;  2W8S A;  3DPC A;  4NWX A;  1K7H A;  1HQA A;  2W5W A;  2W8D A;  1SHQ A;  4UPI A;  1N2L A;  1KHJ A;  4MY4 A;  4KAY A;  3TG0 A;  4KJD A;  1ED9 A;  5IJS A;  3NKM A;  4CXU A;  1KH9 A;  3BDF A;  1AJC A;  3MK2 A;  5EGH A;  4UPH A;  2RH6 A;  1FSU A;  4LR8 A;  3M8Z A;  4GTX A;  1URB A;  1SHN A;  1E2S P;  3TX0 A;  2W5V A;  5GRR A;  5INH A;  4LR7 A;  4GTZ A;  4LR2 A;  5KXA A;  1EW2 A;  3T01 A;  3WAV A;  2ZKT A;  1Y7A A;  1ALK A;  4LRA A;  5LRM A;  4CYR A;  3WAX A;  4ZG9 A;  1P49 A;  2XRG A;  2X98 A;  1EW9 A;  2W5S A;  1EQJ A;  4KM4 A;  4LRF A;  1AJA A;  1O98 A;  2IUC B;  1ELY A;  3NKO A;  3BDG A;  1ELZ A;  4YR1 A;  4UOR A;  3NVL A;  4LRD A;  3UN5 A;  3IGY B;  3CMR A;  1ANJ A;  3E2D A;  3UNY A;  1E3C P;  3UN2 A;  1AJB A;  4FDI A;  4NWJ A;  3SZY A;  1KHK A;  4LR9 A;  4MIV A;  5GOV A;  4ZG6 A;  5C66 A;  4TN0 A;  1ZEB A;  5L0K A;  5DLT A;  4CXS A;  1AUK A;  4LRB A;  1KH4 A;  2GLQ A;  3KD8 A;  3LXQ A;  5EGE A;  2GA3 A;  3NKR A;  1HJK A;  2W5Q A;  2D1G A;  5LIA A;  3M8Y A;  3NKQ A;  2GSU A;  4UPL A;  2IFY A;  3NKP A;  2GSN A;  3ED4 A;  4LRC A;  1HDH A;  3M8W A;  1E33 P;  2G9Y A;  5DLV A;  4B56 A;  5HRT A;  4KAV A;  4KJG A;  3WBH A;  1ZEF A;  2IUC A;  3BDG B;  4MHX A;  3NKN A;  3T02 A;  2W5T A;  4UPK A;  5LQQ A;  3OT9 A;  1URA A;  3BDH A;  1ALJ A;  1KHN A;  4FDJ A;  3UO0 A;  3Q3Q A;  3DYC A;  4GTY A;  3IGZ B;  2W5X A; 
#chains in the Genus database with same CATH topology
 3A52 A;  4CYS A;  3UN3 A;  1Y6V A;  4UOP A;  4QAX A;  5L0E A;  2W5R A;  1N2K A;  3B5Q A;  3T00 A;  1ED8 A;  4UOO A;  4ZGA A;  2QZU A;  1KH7 A;  3IDD A;  1KH5 A;  5K4P A;  4CXK A;  5DLW A;  5LRN A;  1ANI A;  1ZED A;  3M7V A;  1B8J A;  1ALH A;  2XR9 A;  5AJ9 A;  1EJJ A;  1AJD A;  4N7T A;  1O99 A;  5TJ3 A;  1KHL A;  2GSO A;  4ZG7 A;  3WAY A;  3MK1 A;  3SZZ A;  5L0B A;  3TWZ A;  1E1Z P;  4LRE A;  3MK0 A;  1ELX A;  4LQY A;  2ANH A;  1ALI A;  2VQR A;  1EI6 A;  1EW8 A;  5IJQ A;  4GTW A;  3WAW A;  2W8S A;  3DPC A;  4NWX A;  1K7H A;  1HQA A;  2W5W A;  2W8D A;  1SHQ A;  4UPI A;  1N2L A;  1KHJ A;  4MY4 A;  4KAY A;  3TG0 A;  4KJD A;  1ED9 A;  5IJS A;  3NKM A;  4CXU A;  1KH9 A;  3BDF A;  1AJC A;  3MK2 A;  5EGH A;  4UPH A;  2RH6 A;  1FSU A;  4LR8 A;  3M8Z A;  4GTX A;  1URB A;  1SHN A;  1E2S P;  3TX0 A;  2W5V A;  5GRR A;  5INH A;  4LR7 A;  4GTZ A;  4LR2 A;  5KXA A;  1EW2 A;  3T01 A;  3WAV A;  2ZKT A;  1Y7A A;  1ALK A;  4LRA A;  5LRM A;  4CYR A;  3WAX A;  4ZG9 A;  1P49 A;  2XRG A;  2X98 A;  1EW9 A;  2W5S A;  1EQJ A;  4KM4 A;  4LRF A;  1AJA A;  1O98 A;  2IUC B;  1ELY A;  3NKO A;  3BDG A;  1ELZ A;  4YR1 A;  4UOR A;  3NVL A;  4LRD A;  3UN5 A;  3IGY B;  3CMR A;  1ANJ A;  3E2D A;  3UNY A;  1E3C P;  3UN2 A;  1AJB A;  4FDI A;  4NWJ A;  3SZY A;  1KHK A;  4LR9 A;  4MIV A;  5GOV A;  4ZG6 A;  5C66 A;  4TN0 A;  1ZEB A;  5L0K A;  5DLT A;  4CXS A;  1AUK A;  4LRB A;  1KH4 A;  2GLQ A;  3KD8 A;  3LXQ A;  5EGE A;  2GA3 A;  3NKR A;  1HJK A;  2W5Q A;  2D1G A;  5LIA A;  3M8Y A;  3NKQ A;  2GSU A;  4UPL A;  2IFY A;  3NKP A;  2GSN A;  3ED4 A;  4LRC A;  1HDH A;  3M8W A;  1E33 P;  2G9Y A;  5DLV A;  4B56 A;  5HRT A;  4KAV A;  4KJG A;  3WBH A;  1ZEF A;  2IUC A;  3BDG B;  4MHX A;  3NKN A;  3T02 A;  2W5T A;  4UPK A;  5LQQ A;  3OT9 A;  1URA A;  3BDH A;  1ALJ A;  1KHN A;  4FDJ A;  3UO0 A;  3Q3Q A;  3DYC A;  4GTY A;  3IGZ B;  2W5X A; 
#chains in the Genus database with same CATH homology
 3A52 A;  4CYS A;  3UN3 A;  1Y6V A;  4UOP A;  4QAX A;  5L0E A;  2W5R A;  1N2K A;  3B5Q A;  3T00 A;  1ED8 A;  4UOO A;  4ZGA A;  2QZU A;  1KH7 A;  3IDD A;  1KH5 A;  5K4P A;  4CXK A;  5DLW A;  5LRN A;  1ANI A;  1ZED A;  3M7V A;  1B8J A;  1ALH A;  2XR9 A;  5AJ9 A;  1EJJ A;  1AJD A;  4N7T A;  1O99 A;  5TJ3 A;  1KHL A;  2GSO A;  4ZG7 A;  3WAY A;  3MK1 A;  3SZZ A;  5L0B A;  3TWZ A;  1E1Z P;  4LRE A;  3MK0 A;  1ELX A;  4LQY A;  2ANH A;  1ALI A;  2VQR A;  1EI6 A;  1EW8 A;  5IJQ A;  4GTW A;  3WAW A;  2W8S A;  3DPC A;  4NWX A;  1K7H A;  1HQA A;  2W5W A;  2W8D A;  1SHQ A;  4UPI A;  1N2L A;  1KHJ A;  4MY4 A;  4KAY A;  3TG0 A;  4KJD A;  1ED9 A;  5IJS A;  3NKM A;  4CXU A;  1KH9 A;  3BDF A;  1AJC A;  3MK2 A;  5EGH A;  4UPH A;  2RH6 A;  1FSU A;  4LR8 A;  3M8Z A;  4GTX A;  1URB A;  1SHN A;  1E2S P;  3TX0 A;  2W5V A;  5GRR A;  5INH A;  4LR7 A;  4GTZ A;  4LR2 A;  5KXA A;  1EW2 A;  3T01 A;  3WAV A;  2ZKT A;  1Y7A A;  1ALK A;  4LRA A;  5LRM A;  4CYR A;  3WAX A;  4ZG9 A;  1P49 A;  2XRG A;  2X98 A;  1EW9 A;  2W5S A;  1EQJ A;  4KM4 A;  4LRF A;  1AJA A;  1O98 A;  2IUC B;  1ELY A;  3NKO A;  3BDG A;  1ELZ A;  4YR1 A;  4UOR A;  3NVL A;  4LRD A;  3UN5 A;  3IGY B;  3CMR A;  1ANJ A;  3E2D A;  3UNY A;  1E3C P;  3UN2 A;  1AJB A;  4FDI A;  4NWJ A;  3SZY A;  1KHK A;  4LR9 A;  4MIV A;  5GOV A;  4ZG6 A;  5C66 A;  4TN0 A;  1ZEB A;  5L0K A;  5DLT A;  4CXS A;  1AUK A;  4LRB A;  1KH4 A;  2GLQ A;  3KD8 A;  3LXQ A;  5EGE A;  2GA3 A;  3NKR A;  1HJK A;  2W5Q A;  2D1G A;  5LIA A;  3M8Y A;  3NKQ A;  2GSU A;  4UPL A;  2IFY A;  3NKP A;  2GSN A;  3ED4 A;  4LRC A;  1HDH A;  3M8W A;  1E33 P;  2G9Y A;  5DLV A;  4B56 A;  5HRT A;  4KAV A;  4KJG A;  3WBH A;  1ZEF A;  2IUC A;  3BDG B;  4MHX A;  3NKN A;  3T02 A;  2W5T A;  4UPK A;  5LQQ A;  3OT9 A;  1URA A;  3BDH A;  1ALJ A;  1KHN A;  4FDJ A;  3UO0 A;  3Q3Q A;  3DYC A;  4GTY A;  3IGZ B;  2W5X A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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