2D1GA

Structure of francisella tularensis acid phosphatase a (acpa) bound to orthovanadate
Total Genus 180
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
180
Knots found
sequence length
485
structure length
481
Chain Sequence
NSKPNDYGTLQKLFNNANTLKTTTPIKHVVIIFQENNSFDRYFGMYPNAKNPEGEPKFVAKENTPNVNGLTKQLLENNPNTKNPYRLDRNFQPCSQNHEYHQEISSFNGGLMNKFVEHGGHDNDTYKQNCDGQVMGYYDGNTVTALWNYAQNFALNDNTFGTTFGPSTPGALNLVAGANGPAMSPSGNLENIENNYIIDDPNPYYDDCSYGTSKSGDTNTAVAKITDGYNIGHYLTQKGITWGWFQGGFKPTSYSGKTAICDAMSTNKFGVKSRDYIPHHEPFNYWKETSNPHHLAPSDDKYIGSNDQANHQYDISEFWKALDQNNMPAVSYLKAPGYQDGHGGYSNPLDEQEWLVNTINRIQQSKDWDSTAIIIIYDDSDGDYDHVYSPKSQFSDIKGRQGYGPRLPMLVISPYAKANYVDHSLLNQASVLKFIEYNWGIGSVSKYSNDKYSNNILNMFDFNKEQKTLKLILDPKTGLVM
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule keywords acid phosphatase
publication title Structure of Francisella tularensis AcpA: prototype of a unique superfamily of acid phosphatases and phospholipases C
pubmed doi rcsb
source organism Francisella tularensis subsp. novicida
molecule tags Hydrolase
total genus 180
structure length 481
sequence length 485
chains with identical sequence B
other databases KnotProt 2.0: S +31
ec nomenclature ec 3.1.3.2: Acid phosphatase.
pdb deposition date 2005-08-20

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF04185 Phosphoesterase Phosphoesterase family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.720.10 Alpha Beta 3-Layer(aba) Sandwich Alkaline Phosphatase, subunit A Alkaline Phosphatase, subunit A 2d1gA02
4UOOA 1ED8A 3NKMA 3WBHA 2W5TA 4N7TA 5EGEA 3M8WA 3Q3QA 1ZEFA 1AUKA 3WAYA 3IGZB 4CYRA 4LRCA 4KJDA 4UPKA 3BDGB 3NKRA 4NWJA 3SZZA 3WAXA 1ELXA 3OT9A 1ELYA 1B8JA 2XRGA 1ALKA 3M8ZA 3WAVA 5LRMA 1E33P 5GOVA 4ZG9A 1N2LA 2W8SA 4FDIA 1E1ZP 3T02A 5IJSA 3NVLA 1URBA 1O98A 2VQRA 3MK1A 4B56A 3M7VA 2ANHA 1E2SP 5HRTA 1ELZA 3MK2A 4FDJA 5TJ3A 3NKOA 4CYSA 3B5QA 4UPHA 3ED4A 5GRRA 1KH4A 3T01A 3TX0A 3UN2A 1EW2A 5KXAA 5K4PA 2W5SA 4YR1A 1AJCA 3A52A 2W5RA 2W5QA 1HDHA 1KH7A 3KD8A 1K7HA 1EW9A 4KJGA 4LR9A 4UORA 3E2DA 5L0EA 1ANJA 4KM4A 3IDDA 2IUCB 2GSNA 3BDFA 1AJDA 1HJKA 1ANIA 2W5WA 1KH5A 1SHQA 2W5VA 5L0KA 5LIAA 4UPIA 3IGYB 4LRFA 1EI6A 4LR8A 3TG0A 3BDGA 1ALHA 3NKQA 4GTWA 4GTYA 1EW8A 2X98A 4QAXA 3DPCA 3WAWA 2GSUA 4LR2A 4CXSA 1ED9A 1FSUA 1URAA 5INHA 2RH6A 3UO0A 4LRAA 2GA3A 1O99A 4LRDA 1N2KA 4LRBA 5DLTA 4UPLA 1ZEBA 2D1GA 5AJ9A 2W5XA 4MIVA 4GTXA 2XR9A 3NKPA 4LQYA 2IFYA 1KHNA 1ALJA 1Y6VA 2W8DA 1EQJA 3T00A 2G9YA 3M8YA 4KAVA 3BDHA 4LR7A 5EGHA 1AJAA 1KHKA 3UNYA 4ZG7A 5DLWA 4ZGAA 1EJJA 2ZKTA 4KAYA 3TWZA 5DLVA 3CMRA 3DYCA 1E3CP 3MK0A 2IUCA 3UN5A 2GSOA 4UOPA 1ZEDA 2QZUA 4MY4A 4CXUA 4GTZA 3NKNA 3LXQA 5IJQA 4NWXA 5LQQA 4LREA 1P49A 4MHXA 3UN3A 5C66A 4ZG6A 1KHJA 2GLQA 1Y7AA 5LRNA 1HQAA 5L0BA 1KHLA 1SHNA 4CXKA 1ALIA 4TN0A 1KH9A 1AJBA 3SZYA
chains in the Genus database with same CATH superfamily
4UOOA 1ED8A 3NKMA 3WBHA 2W5TA 4N7TA 5EGEA 3M8WA 3Q3QA 1ZEFA 1AUKA 3WAYA 3IGZB 4CYRA 4LRCA 4KJDA 4UPKA 3BDGB 3NKRA 4NWJA 3SZZA 3WAXA 1ELXA 3OT9A 1ELYA 1B8JA 2XRGA 1ALKA 3M8ZA 3WAVA 5LRMA 1E33P 5GOVA 4ZG9A 1N2LA 2W8SA 4FDIA 1E1ZP 3T02A 5IJSA 3NVLA 1URBA 1O98A 2VQRA 3MK1A 4B56A 3M7VA 2ANHA 1E2SP 5HRTA 1ELZA 3MK2A 4FDJA 5TJ3A 3NKOA 4CYSA 3B5QA 4UPHA 3ED4A 5GRRA 1KH4A 3T01A 3TX0A 3UN2A 1EW2A 5KXAA 5K4PA 2W5SA 4YR1A 1AJCA 3A52A 2W5RA 2W5QA 1HDHA 1KH7A 3KD8A 1K7HA 1EW9A 4KJGA 4LR9A 4UORA 3E2DA 5L0EA 1ANJA 4KM4A 3IDDA 2IUCB 2GSNA 3BDFA 1AJDA 1HJKA 1ANIA 2W5WA 1KH5A 1SHQA 2W5VA 5L0KA 5LIAA 4UPIA 3IGYB 4LRFA 1EI6A 4LR8A 3TG0A 3BDGA 1ALHA 3NKQA 4GTWA 4GTYA 1EW8A 2X98A 4QAXA 3DPCA 3WAWA 2GSUA 4LR2A 4CXSA 1ED9A 1FSUA 1URAA 5INHA 2RH6A 3UO0A 4LRAA 2GA3A 1O99A 4LRDA 1N2KA 4LRBA 5DLTA 4UPLA 1ZEBA 2D1GA 5AJ9A 2W5XA 4MIVA 4GTXA 2XR9A 3NKPA 4LQYA 2IFYA 1KHNA 1ALJA 1Y6VA 2W8DA 1EQJA 3T00A 2G9YA 3M8YA 4KAVA 3BDHA 4LR7A 5EGHA 1AJAA 1KHKA 3UNYA 4ZG7A 5DLWA 4ZGAA 1EJJA 2ZKTA 4KAYA 3TWZA 5DLVA 3CMRA 3DYCA 1E3CP 3MK0A 2IUCA 3UN5A 2GSOA 4UOPA 1ZEDA 2QZUA 4MY4A 4CXUA 4GTZA 3NKNA 3LXQA 5IJQA 4NWXA 5LQQA 4LREA 1P49A 4MHXA 3UN3A 5C66A 4ZG6A 1KHJA 2GLQA 1Y7AA 5LRNA 1HQAA 5L0BA 1KHLA 1SHNA 4CXKA 1ALIA 4TN0A 1KH9A 1AJBA 3SZYA
chains in the Genus database with same CATH topology
4UOOA 1ED8A 3NKMA 3WBHA 2W5TA 4N7TA 5EGEA 3M8WA 3Q3QA 1ZEFA 1AUKA 3WAYA 3IGZB 4CYRA 4LRCA 4KJDA 4UPKA 3BDGB 3NKRA 4NWJA 3SZZA 3WAXA 1ELXA 3OT9A 1ELYA 1B8JA 2XRGA 1ALKA 3M8ZA 3WAVA 5LRMA 1E33P 5GOVA 4ZG9A 1N2LA 2W8SA 4FDIA 1E1ZP 3T02A 5IJSA 3NVLA 1URBA 1O98A 2VQRA 3MK1A 4B56A 3M7VA 2ANHA 1E2SP 5HRTA 1ELZA 3MK2A 4FDJA 5TJ3A 3NKOA 4CYSA 3B5QA 4UPHA 3ED4A 5GRRA 1KH4A 3T01A 3TX0A 3UN2A 1EW2A 5KXAA 5K4PA 2W5SA 4YR1A 1AJCA 3A52A 2W5RA 2W5QA 1HDHA 1KH7A 3KD8A 1K7HA 1EW9A 4KJGA 4LR9A 4UORA 3E2DA 5L0EA 1ANJA 4KM4A 3IDDA 2IUCB 2GSNA 3BDFA 1AJDA 1HJKA 1ANIA 2W5WA 1KH5A 1SHQA 2W5VA 5L0KA 5LIAA 4UPIA 3IGYB 4LRFA 1EI6A 4LR8A 3TG0A 3BDGA 1ALHA 3NKQA 4GTWA 4GTYA 1EW8A 2X98A 4QAXA 3DPCA 3WAWA 2GSUA 4LR2A 4CXSA 1ED9A 1FSUA 1URAA 5INHA 2RH6A 3UO0A 4LRAA 2GA3A 1O99A 4LRDA 1N2KA 4LRBA 5DLTA 4UPLA 1ZEBA 2D1GA 5AJ9A 2W5XA 4MIVA 4GTXA 2XR9A 3NKPA 4LQYA 2IFYA 1KHNA 1ALJA 1Y6VA 2W8DA 1EQJA 3T00A 2G9YA 3M8YA 4KAVA 3BDHA 4LR7A 5EGHA 1AJAA 1KHKA 3UNYA 4ZG7A 5DLWA 4ZGAA 1EJJA 2ZKTA 4KAYA 3TWZA 5DLVA 3CMRA 3DYCA 1E3CP 3MK0A 2IUCA 3UN5A 2GSOA 4UOPA 1ZEDA 2QZUA 4MY4A 4CXUA 4GTZA 3NKNA 3LXQA 5IJQA 4NWXA 5LQQA 4LREA 1P49A 4MHXA 3UN3A 5C66A 4ZG6A 1KHJA 2GLQA 1Y7AA 5LRNA 1HQAA 5L0BA 1KHLA 1SHNA 4CXKA 1ALIA 4TN0A 1KH9A 1AJBA 3SZYA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4UOO A;  1ED8 A;  3NKM A;  3WBH A;  2W5T A;  4N7T A;  5EGE A;  3M8W A;  3Q3Q A;  1ZEF A;  1AUK A;  3WAY A;  3IGZ B;  4CYR A;  4LRC A;  4KJD A;  4UPK A;  3BDG B;  3NKR A;  4NWJ A;  3SZZ A;  3WAX A;  1ELX A;  3OT9 A;  1ELY A;  1B8J A;  2XRG A;  1ALK A;  3M8Z A;  3WAV A;  5LRM A;  1E33 P;  5GOV A;  4ZG9 A;  1N2L A;  2W8S A;  4FDI A;  1E1Z P;  3T02 A;  5IJS A;  3NVL A;  1URB A;  1O98 A;  2VQR A;  3MK1 A;  4B56 A;  3M7V A;  2ANH A;  1E2S P;  5HRT A;  1ELZ A;  3MK2 A;  4FDJ A;  5TJ3 A;  3NKO A;  4CYS A;  3B5Q A;  4UPH A;  3ED4 A;  5GRR A;  1KH4 A;  3T01 A;  3TX0 A;  3UN2 A;  1EW2 A;  5KXA A;  5K4P A;  2W5S A;  4YR1 A;  1AJC A;  3A52 A;  2W5R A;  2W5Q A;  1HDH A;  1KH7 A;  3KD8 A;  1K7H A;  1EW9 A;  4KJG A;  4LR9 A;  4UOR A;  3E2D A;  5L0E A;  1ANJ A;  4KM4 A;  3IDD A;  2IUC B;  2GSN A;  3BDF A;  1AJD A;  1HJK A;  1ANI A;  2W5W A;  1KH5 A;  1SHQ A;  2W5V A;  5L0K A;  5LIA A;  4UPI A;  3IGY B;  4LRF A;  1EI6 A;  4LR8 A;  3TG0 A;  3BDG A;  1ALH A;  3NKQ A;  4GTW A;  4GTY A;  1EW8 A;  2X98 A;  4QAX A;  3DPC A;  3WAW A;  2GSU A;  4LR2 A;  4CXS A;  1ED9 A;  1FSU A;  1URA A;  5INH A;  2RH6 A;  3UO0 A;  4LRA A;  2GA3 A;  1O99 A;  4LRD A;  1N2K A;  4LRB A;  5DLT A;  4UPL A;  1ZEB A;  2D1G A;  5AJ9 A;  2W5X A;  4MIV A;  4GTX A;  2XR9 A;  3NKP A;  4LQY A;  2IFY A;  1KHN A;  1ALJ A;  1Y6V A;  2W8D A;  1EQJ A;  3T00 A;  2G9Y A;  3M8Y A;  4KAV A;  3BDH A;  4LR7 A;  5EGH A;  1AJA A;  1KHK A;  3UNY A;  4ZG7 A;  5DLW A;  4ZGA A;  1EJJ A;  2ZKT A;  4KAY A;  3TWZ A;  5DLV A;  3CMR A;  3DYC A;  1E3C P;  3MK0 A;  2IUC A;  3UN5 A;  2GSO A;  4UOP A;  1ZED A;  2QZU A;  4MY4 A;  4CXU A;  4GTZ A;  3NKN A;  3LXQ A;  5IJQ A;  4NWX A;  5LQQ A;  4LRE A;  1P49 A;  4MHX A;  3UN3 A;  5C66 A;  4ZG6 A;  1KHJ A;  2GLQ A;  1Y7A A;  5LRN A;  1HQA A;  5L0B A;  1KHL A;  1SHN A;  4CXK A;  1ALI A;  4TN0 A;  1KH9 A;  1AJB A;  3SZY A; 
#chains in the Genus database with same CATH topology
 4UOO A;  1ED8 A;  3NKM A;  3WBH A;  2W5T A;  4N7T A;  5EGE A;  3M8W A;  3Q3Q A;  1ZEF A;  1AUK A;  3WAY A;  3IGZ B;  4CYR A;  4LRC A;  4KJD A;  4UPK A;  3BDG B;  3NKR A;  4NWJ A;  3SZZ A;  3WAX A;  1ELX A;  3OT9 A;  1ELY A;  1B8J A;  2XRG A;  1ALK A;  3M8Z A;  3WAV A;  5LRM A;  1E33 P;  5GOV A;  4ZG9 A;  1N2L A;  2W8S A;  4FDI A;  1E1Z P;  3T02 A;  5IJS A;  3NVL A;  1URB A;  1O98 A;  2VQR A;  3MK1 A;  4B56 A;  3M7V A;  2ANH A;  1E2S P;  5HRT A;  1ELZ A;  3MK2 A;  4FDJ A;  5TJ3 A;  3NKO A;  4CYS A;  3B5Q A;  4UPH A;  3ED4 A;  5GRR A;  1KH4 A;  3T01 A;  3TX0 A;  3UN2 A;  1EW2 A;  5KXA A;  5K4P A;  2W5S A;  4YR1 A;  1AJC A;  3A52 A;  2W5R A;  2W5Q A;  1HDH A;  1KH7 A;  3KD8 A;  1K7H A;  1EW9 A;  4KJG A;  4LR9 A;  4UOR A;  3E2D A;  5L0E A;  1ANJ A;  4KM4 A;  3IDD A;  2IUC B;  2GSN A;  3BDF A;  1AJD A;  1HJK A;  1ANI A;  2W5W A;  1KH5 A;  1SHQ A;  2W5V A;  5L0K A;  5LIA A;  4UPI A;  3IGY B;  4LRF A;  1EI6 A;  4LR8 A;  3TG0 A;  3BDG A;  1ALH A;  3NKQ A;  4GTW A;  4GTY A;  1EW8 A;  2X98 A;  4QAX A;  3DPC A;  3WAW A;  2GSU A;  4LR2 A;  4CXS A;  1ED9 A;  1FSU A;  1URA A;  5INH A;  2RH6 A;  3UO0 A;  4LRA A;  2GA3 A;  1O99 A;  4LRD A;  1N2K A;  4LRB A;  5DLT A;  4UPL A;  1ZEB A;  2D1G A;  5AJ9 A;  2W5X A;  4MIV A;  4GTX A;  2XR9 A;  3NKP A;  4LQY A;  2IFY A;  1KHN A;  1ALJ A;  1Y6V A;  2W8D A;  1EQJ A;  3T00 A;  2G9Y A;  3M8Y A;  4KAV A;  3BDH A;  4LR7 A;  5EGH A;  1AJA A;  1KHK A;  3UNY A;  4ZG7 A;  5DLW A;  4ZGA A;  1EJJ A;  2ZKT A;  4KAY A;  3TWZ A;  5DLV A;  3CMR A;  3DYC A;  1E3C P;  3MK0 A;  2IUC A;  3UN5 A;  2GSO A;  4UOP A;  1ZED A;  2QZU A;  4MY4 A;  4CXU A;  4GTZ A;  3NKN A;  3LXQ A;  5IJQ A;  4NWX A;  5LQQ A;  4LRE A;  1P49 A;  4MHX A;  3UN3 A;  5C66 A;  4ZG6 A;  1KHJ A;  2GLQ A;  1Y7A A;  5LRN A;  1HQA A;  5L0B A;  1KHL A;  1SHN A;  4CXK A;  1ALI A;  4TN0 A;  1KH9 A;  1AJB A;  3SZY A; 
#chains in the Genus database with same CATH homology
 4UOO A;  1ED8 A;  3NKM A;  3WBH A;  2W5T A;  4N7T A;  5EGE A;  3M8W A;  3Q3Q A;  1ZEF A;  1AUK A;  3WAY A;  3IGZ B;  4CYR A;  4LRC A;  4KJD A;  4UPK A;  3BDG B;  3NKR A;  4NWJ A;  3SZZ A;  3WAX A;  1ELX A;  3OT9 A;  1ELY A;  1B8J A;  2XRG A;  1ALK A;  3M8Z A;  3WAV A;  5LRM A;  1E33 P;  5GOV A;  4ZG9 A;  1N2L A;  2W8S A;  4FDI A;  1E1Z P;  3T02 A;  5IJS A;  3NVL A;  1URB A;  1O98 A;  2VQR A;  3MK1 A;  4B56 A;  3M7V A;  2ANH A;  1E2S P;  5HRT A;  1ELZ A;  3MK2 A;  4FDJ A;  5TJ3 A;  3NKO A;  4CYS A;  3B5Q A;  4UPH A;  3ED4 A;  5GRR A;  1KH4 A;  3T01 A;  3TX0 A;  3UN2 A;  1EW2 A;  5KXA A;  5K4P A;  2W5S A;  4YR1 A;  1AJC A;  3A52 A;  2W5R A;  2W5Q A;  1HDH A;  1KH7 A;  3KD8 A;  1K7H A;  1EW9 A;  4KJG A;  4LR9 A;  4UOR A;  3E2D A;  5L0E A;  1ANJ A;  4KM4 A;  3IDD A;  2IUC B;  2GSN A;  3BDF A;  1AJD A;  1HJK A;  1ANI A;  2W5W A;  1KH5 A;  1SHQ A;  2W5V A;  5L0K A;  5LIA A;  4UPI A;  3IGY B;  4LRF A;  1EI6 A;  4LR8 A;  3TG0 A;  3BDG A;  1ALH A;  3NKQ A;  4GTW A;  4GTY A;  1EW8 A;  2X98 A;  4QAX A;  3DPC A;  3WAW A;  2GSU A;  4LR2 A;  4CXS A;  1ED9 A;  1FSU A;  1URA A;  5INH A;  2RH6 A;  3UO0 A;  4LRA A;  2GA3 A;  1O99 A;  4LRD A;  1N2K A;  4LRB A;  5DLT A;  4UPL A;  1ZEB A;  2D1G A;  5AJ9 A;  2W5X A;  4MIV A;  4GTX A;  2XR9 A;  3NKP A;  4LQY A;  2IFY A;  1KHN A;  1ALJ A;  1Y6V A;  2W8D A;  1EQJ A;  3T00 A;  2G9Y A;  3M8Y A;  4KAV A;  3BDH A;  4LR7 A;  5EGH A;  1AJA A;  1KHK A;  3UNY A;  4ZG7 A;  5DLW A;  4ZGA A;  1EJJ A;  2ZKT A;  4KAY A;  3TWZ A;  5DLV A;  3CMR A;  3DYC A;  1E3C P;  3MK0 A;  2IUC A;  3UN5 A;  2GSO A;  4UOP A;  1ZED A;  2QZU A;  4MY4 A;  4CXU A;  4GTZ A;  3NKN A;  3LXQ A;  5IJQ A;  4NWX A;  5LQQ A;  4LRE A;  1P49 A;  4MHX A;  3UN3 A;  5C66 A;  4ZG6 A;  1KHJ A;  2GLQ A;  1Y7A A;  5LRN A;  1HQA A;  5L0B A;  1KHL A;  1SHN A;  4CXK A;  1ALI A;  4TN0 A;  1KH9 A;  1AJB A;  3SZY A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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