2D1KB

Ternary complex of the wh2 domain of mim with actin-dnase i
Total Genus 81
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
81
sequence length
260
structure length
260
Chain Sequence
LKIAAFNIRTFGETKMSNATLASYIVRIVRRYDIVLIQEVRDSHLVAVGKLLDYLNQDDPNTYHYVVSEPLGRNSYKERYLFLFRPNKVSVLDTYQYDDGCESCGNDSFSREPAVVKFSSHSTKVKEFAIVALHSAPSDAVAEINSLYDVYLDVQQKWHLNDVMLMGDFNADCSYVTSSQWSSIRLRTSSTFQWLIPDSADTTATSTNCAYDRIVVAGSLLQSSVVPGSAAPFDFQAAYGLSNEMALAISDHYPVEVTLT
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural basis for the actin-binding function of missing-in-metastasis
pubmed doi rcsb
molecule tags Structural protein
molecule keywords Actin, alpha skeletal muscle
total genus 81
structure length 260
sequence length 260
ec nomenclature ec 3.1.21.1: Deoxyribonuclease I.
pdb deposition date 2005-08-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF03372 Exo_endo_phos Endonuclease/Exonuclease/phosphatase family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.60.10.10 Alpha Beta 4-Layer Sandwich Deoxyribonuclease I; Chain A Endonuclease/exonuclease/phosphatase 2d1kB00
4K6LF 2XSWA 2DDTA 3G2CA 2ISIA 3TEBA 3MTCA 5CFGA 3I41A 5DG0A 3FZIA 4C1RA 5DV4A 1I9ZA 4F1HB 5DFFA 3I5VA 4PUQA 4CMLA 4QH9A 4GZ1A 3G2DA 3G4TA 5DV2A 5J3PA 4GZ2A 2A41B 3L1WA 4QHDA 1YJHA 4L20A 4B5HA 5J8NA 2V0SA 3W3DB 2IMQX 4CMNA 3G3CA 4GZ0A 4B5IA 2DDSA 2A3ZB 5DFHA 4B5JA 5A7JA 5CFEA 3N9VA 4RUWA 2DNJA 5HT2A 5J3SA 4FPVA 1SI6X 4LNDA 4FVAA 1DNKA 5INMA 2D1KB 3G1KA 3CJCD 4F1HA 4L1ZA 3G6SA 1ZWXA 3G91A 4L21A 3U8UA 1E9NA 4A9CA 5DFIA 1HD7A 1I9YA 3I48A 1ATND 1NTFA 5INKA 5INPA 3G0RA 3MPRA 4JG3A 2A42B 2EI9A 5A7IA 3I46A 3K55A 1BIXA 4GEWA 4GYZA 2VOAA 3G3YA 5INLA 1DEWA 5INNA 2F1NA 5J42A 3NGNA 3G00A 1AKOA 4B5FA 4F1IA 2A40B 3NGOA 3G0AA 2F2FB 4B5GA 4L1YA 4QHEA 4IEMA 4B5MA 1DE9A 1VYBA 1DE8A 5J3ZA 4F1RA 2JC5A 3W2YA 2O3CA 5EWTA 3NR8A 1SR4B 5DFJA 2UYRX 3GA6A 3W2XA 5INQA 2O3HA 2DDRA 2J63A 1WDUA 1Y21A 5INOA 2V0RA 4AWNA 2JC4A 3G38A 3DNIA 3WCXA 3NGQA 3G8VA
chains in the Genus database with same CATH superfamily
4K6LF 2XSWA 2DDTA 3G2CA 2ISIA 3TEBA 3MTCA 5CFGA 3I41A 5DG0A 3FZIA 4C1RA 5DV4A 1I9ZA 4F1HB 5DFFA 3I5VA 4PUQA 4CMLA 4QH9A 4GZ1A 3G2DA 3G4TA 5DV2A 5J3PA 4GZ2A 2A41B 3L1WA 4QHDA 1YJHA 4L20A 4B5HA 5J8NA 2V0SA 3W3DB 2IMQX 4CMNA 3G3CA 4GZ0A 4B5IA 2DDSA 2A3ZB 5DFHA 4B5JA 5A7JA 5CFEA 3N9VA 4RUWA 2DNJA 5HT2A 5J3SA 4FPVA 1SI6X 4LNDA 4FVAA 1DNKA 5INMA 2D1KB 3G1KA 3CJCD 4F1HA 4L1ZA 3G6SA 1ZWXA 3G91A 4L21A 3U8UA 1E9NA 4A9CA 5DFIA 1HD7A 1I9YA 3I48A 1ATND 1NTFA 5INKA 5INPA 3G0RA 3MPRA 4JG3A 2A42B 2EI9A 5A7IA 3I46A 3K55A 1BIXA 4GEWA 4GYZA 2VOAA 3G3YA 5INLA 1DEWA 5INNA 2F1NA 5J42A 3NGNA 3G00A 1AKOA 4B5FA 4F1IA 2A40B 3NGOA 3G0AA 2F2FB 4B5GA 4L1YA 4QHEA 4IEMA 4B5MA 1DE9A 1VYBA 1DE8A 5J3ZA 4F1RA 2JC5A 3W2YA 2O3CA 5EWTA 3NR8A 1SR4B 5DFJA 2UYRX 3GA6A 3W2XA 5INQA 2O3HA 2DDRA 2J63A 1WDUA 1Y21A 5INOA 2V0RA 4AWNA 2JC4A 3G38A 3DNIA 3WCXA 3NGQA 3G8VA
chains in the Genus database with same CATH topology
4K6LF 2XSWA 2DDTA 3G2CA 2ISIA 3TEBA 3MTCA 5CFGA 3I41A 5DG0A 3FZIA 4C1RA 5DV4A 1I9ZA 4F1HB 5DFFA 3I5VA 4PUQA 4CMLA 4QH9A 4GZ1A 3G2DA 3G4TA 5DV2A 5J3PA 4GZ2A 2A41B 3L1WA 4QHDA 1YJHA 4L20A 4B5HA 5J8NA 2V0SA 3W3DB 2IMQX 4CMNA 3G3CA 4GZ0A 4B5IA 2DDSA 2A3ZB 5DFHA 4B5JA 5A7JA 5CFEA 3N9VA 4RUWA 2DNJA 5HT2A 5J3SA 4FPVA 1SI6X 4LNDA 4FVAA 1DNKA 5INMA 2D1KB 3G1KA 3CJCD 4F1HA 4L1ZA 3G6SA 1ZWXA 3G91A 4L21A 3U8UA 1E9NA 4A9CA 5DFIA 1HD7A 1I9YA 3I48A 1ATND 1NTFA 5INKA 5INPA 3G0RA 3MPRA 4JG3A 2A42B 2EI9A 5A7IA 3I46A 3K55A 1BIXA 4GEWA 4GYZA 2VOAA 3G3YA 5INLA 1DEWA 5INNA 2F1NA 5J42A 3NGNA 3G00A 1AKOA 4B5FA 4F1IA 2A40B 3NGOA 3G0AA 2F2FB 4B5GA 4L1YA 4QHEA 4IEMA 4B5MA 1DE9A 1VYBA 1DE8A 5J3ZA 4F1RA 2JC5A 3W2YA 2O3CA 5EWTA 3NR8A 1SR4B 5DFJA 2UYRX 3GA6A 3W2XA 5INQA 2O3HA 2DDRA 2J63A 1WDUA 1Y21A 5INOA 2V0RA 4AWNA 2JC4A 3G38A 3DNIA 3WCXA 3NGQA 3G8VA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4K6L F;  2XSW A;  2DDT A;  3G2C A;  2ISI A;  3TEB A;  3MTC A;  5CFG A;  3I41 A;  5DG0 A;  3FZI A;  4C1R A;  5DV4 A;  1I9Z A;  4F1H B;  5DFF A;  3I5V A;  4PUQ A;  4CML A;  4QH9 A;  4GZ1 A;  3G2D A;  3G4T A;  5DV2 A;  5J3P A;  4GZ2 A;  2A41 B;  3L1W A;  4QHD A;  1YJH A;  4L20 A;  4B5H A;  5J8N A;  2V0S A;  3W3D B;  2IMQ X;  4CMN A;  3G3C A;  4GZ0 A;  4B5I A;  2DDS A;  2A3Z B;  5DFH A;  4B5J A;  5A7J A;  5CFE A;  3N9V A;  4RUW A;  2DNJ A;  5HT2 A;  5J3S A;  4FPV A;  1SI6 X;  4LND A;  4FVA A;  1DNK A;  5INM A;  2D1K B;  3G1K A;  3CJC D;  4F1H A;  4L1Z A;  3G6S A;  1ZWX A;  3G91 A;  4L21 A;  3U8U A;  1E9N A;  4A9C A;  5DFI A;  1HD7 A;  1I9Y A;  3I48 A;  1ATN D;  1NTF A;  5INK A;  5INP A;  3G0R A;  3MPR A;  4JG3 A;  2A42 B;  2EI9 A;  5A7I A;  3I46 A;  3K55 A;  1BIX A;  4GEW A;  4GYZ A;  2VOA A;  3G3Y A;  5INL A;  1DEW A;  5INN A;  2F1N A;  5J42 A;  3NGN A;  3G00 A;  1AKO A;  4B5F A;  4F1I A;  2A40 B;  3NGO A;  3G0A A;  2F2F B;  4B5G A;  4L1Y A;  4QHE A;  4IEM A;  4B5M A;  1DE9 A;  1VYB A;  1DE8 A;  5J3Z A;  4F1R A;  2JC5 A;  3W2Y A;  2O3C A;  5EWT A;  3NR8 A;  1SR4 B;  5DFJ A;  2UYR X;  3GA6 A;  3W2X A;  5INQ A;  2O3H A;  2DDR A;  2J63 A;  1WDU A;  1Y21 A;  5INO A;  2V0R A;  4AWN A;  2JC4 A;  3G38 A;  3DNI A;  3WCX A;  3NGQ A;  3G8V A; 
#chains in the Genus database with same CATH topology
 4K6L F;  2XSW A;  2DDT A;  3G2C A;  2ISI A;  3TEB A;  3MTC A;  5CFG A;  3I41 A;  5DG0 A;  3FZI A;  4C1R A;  5DV4 A;  1I9Z A;  4F1H B;  5DFF A;  3I5V A;  4PUQ A;  4CML A;  4QH9 A;  4GZ1 A;  3G2D A;  3G4T A;  5DV2 A;  5J3P A;  4GZ2 A;  2A41 B;  3L1W A;  4QHD A;  1YJH A;  4L20 A;  4B5H A;  5J8N A;  2V0S A;  3W3D B;  2IMQ X;  4CMN A;  3G3C A;  4GZ0 A;  4B5I A;  2DDS A;  2A3Z B;  5DFH A;  4B5J A;  5A7J A;  5CFE A;  3N9V A;  4RUW A;  2DNJ A;  5HT2 A;  5J3S A;  4FPV A;  1SI6 X;  4LND A;  4FVA A;  1DNK A;  5INM A;  2D1K B;  3G1K A;  3CJC D;  4F1H A;  4L1Z A;  3G6S A;  1ZWX A;  3G91 A;  4L21 A;  3U8U A;  1E9N A;  4A9C A;  5DFI A;  1HD7 A;  1I9Y A;  3I48 A;  1ATN D;  1NTF A;  5INK A;  5INP A;  3G0R A;  3MPR A;  4JG3 A;  2A42 B;  2EI9 A;  5A7I A;  3I46 A;  3K55 A;  1BIX A;  4GEW A;  4GYZ A;  2VOA A;  3G3Y A;  5INL A;  1DEW A;  5INN A;  2F1N A;  5J42 A;  3NGN A;  3G00 A;  1AKO A;  4B5F A;  4F1I A;  2A40 B;  3NGO A;  3G0A A;  2F2F B;  4B5G A;  4L1Y A;  4QHE A;  4IEM A;  4B5M A;  1DE9 A;  1VYB A;  1DE8 A;  5J3Z A;  4F1R A;  2JC5 A;  3W2Y A;  2O3C A;  5EWT A;  3NR8 A;  1SR4 B;  5DFJ A;  2UYR X;  3GA6 A;  3W2X A;  5INQ A;  2O3H A;  2DDR A;  2J63 A;  1WDU A;  1Y21 A;  5INO A;  2V0R A;  4AWN A;  2JC4 A;  3G38 A;  3DNI A;  3WCX A;  3NGQ A;  3G8V A; 
#chains in the Genus database with same CATH homology
 4K6L F;  2XSW A;  2DDT A;  3G2C A;  2ISI A;  3TEB A;  3MTC A;  5CFG A;  3I41 A;  5DG0 A;  3FZI A;  4C1R A;  5DV4 A;  1I9Z A;  4F1H B;  5DFF A;  3I5V A;  4PUQ A;  4CML A;  4QH9 A;  4GZ1 A;  3G2D A;  3G4T A;  5DV2 A;  5J3P A;  4GZ2 A;  2A41 B;  3L1W A;  4QHD A;  1YJH A;  4L20 A;  4B5H A;  5J8N A;  2V0S A;  3W3D B;  2IMQ X;  4CMN A;  3G3C A;  4GZ0 A;  4B5I A;  2DDS A;  2A3Z B;  5DFH A;  4B5J A;  5A7J A;  5CFE A;  3N9V A;  4RUW A;  2DNJ A;  5HT2 A;  5J3S A;  4FPV A;  1SI6 X;  4LND A;  4FVA A;  1DNK A;  5INM A;  2D1K B;  3G1K A;  3CJC D;  4F1H A;  4L1Z A;  3G6S A;  1ZWX A;  3G91 A;  4L21 A;  3U8U A;  1E9N A;  4A9C A;  5DFI A;  1HD7 A;  1I9Y A;  3I48 A;  1ATN D;  1NTF A;  5INK A;  5INP A;  3G0R A;  3MPR A;  4JG3 A;  2A42 B;  2EI9 A;  5A7I A;  3I46 A;  3K55 A;  1BIX A;  4GEW A;  4GYZ A;  2VOA A;  3G3Y A;  5INL A;  1DEW A;  5INN A;  2F1N A;  5J42 A;  3NGN A;  3G00 A;  1AKO A;  4B5F A;  4F1I A;  2A40 B;  3NGO A;  3G0A A;  2F2F B;  4B5G A;  4L1Y A;  4QHE A;  4IEM A;  4B5M A;  1DE9 A;  1VYB A;  1DE8 A;  5J3Z A;  4F1R A;  2JC5 A;  3W2Y A;  2O3C A;  5EWT A;  3NR8 A;  1SR4 B;  5DFJ A;  2UYR X;  3GA6 A;  3W2X A;  5INQ A;  2O3H A;  2DDR A;  2J63 A;  1WDU A;  1Y21 A;  5INO A;  2V0R A;  4AWN A;  2JC4 A;  3G38 A;  3DNI A;  3WCX A;  3NGQ A;  3G8V A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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