2D8ZA

Solution structure of the third lim domain of four and a half lim domains protein 2 (fhl-2)
Total Genus 6
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
6
sequence length
70
structure length
70
Chain Sequence
GSSGSSGCVQCKKPITTGGVTYREQPWHKECFVCTACRKQLSGQRFTARDDFAYCLNCFCDLYASGPSSG
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Solution structure of the third LIM domain of Four and a half LIM domains protein 2 (FHL-2)
rcsb
molecule tags Signaling protein, structural protein
source organism Homo sapiens
molecule keywords Four and a half LIM domains 2
total genus 6
structure length 70
sequence length 70
ec nomenclature
pdb deposition date 2005-12-08

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00412 LIM LIM domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.10.110.10 Mainly Beta Ribbon Cysteine Rich Protein Cysteine Rich Protein 2d8zA00
2JTNA 1NYPA 2CUPA 2KBXB 1X4LA 4JCJA 1M3VA 1X64A 2D8ZA 2L4ZA 1WYHA 2D8YA 2MBVA 1G47A 2O10A 2XJZA 1J2OA 2IYBE 2LXDA 2XQNT 3MMKA 2DARA 1U5SB 1IBIA 1X6AA 2YPAC 1CTLA 2L6YB 1X62A 2EHEA 2CORA 3IXEB 4HI8B 2DFYC 2DLOA 4KFZA 1B8TA 1QLIA 1X63A 1X61A 1CXXA 1RUTX 1WIGA 2CU8A 2LZUA 2XJYA 2DJ7A 2L6ZC 2MIUA 2CO8A 1A7IA 1IMLA 2CUQA 2EGQA 2O13A 1X3HA 2CURA 1V6GA 4HI9B 2D8XA 3F6QB 1X68A
chains in the Genus database with same CATH superfamily
2KBXB 3ZPOA 1X4LA 5FXVA 1X64A 2L4ZA 2D8YA 5FXXA 3ZLIA 1J2OA 5FXWA 5A1LA 3MMKA 5FY7A 1IBIA 1X62A 3IXEB 3AVRA 5FP3A 1X63A 2CU8A 1RUTX 5LKTA 4BHWA 2L6ZC 2MIUA 1IMLA 3NIMA 2CURA 1V6GA 4HI9B 2MBVA 1G47A 2XJZA 1X6AA 2YPAC 4EZ4A 4HI8B 2DLOA 1B8TA 4UF0B 1CXXA 1WIGA 2XJYA 2XUEA 3AVSA 2O13A 5LKXA 4EYUA 4EZHA 4JCJA 1M3VA 4UF0A 1WYHA 5FY1A 2IYBE 2LXDA 2DARA 1U5SB 2L6YB 2EHEA 2DFYC 1X61A 2LZUA 5LKUA 3NISA 2EGQA 5LKZA 1X68A 2JTNA 1NYPA 2CUPA 3NIKA 2D8ZA 3NIHA 2O10A 2XQNT 5FXZA 3NIJA 1CTLA 2CORA 4ASKA 4KFZA 1QLIA 3NILA 2DJ7A 2CO8A 1A7IA 2CUQA 5FY0A 5FYMA 3NINA 1X3HA 2D8XA 3F6QB
chains in the Genus database with same CATH topology
2KBXB 3ZPOA 1X4LA 5FXVA 1X64A 2L4ZA 2D8YA 5FXXA 3ZLIA 1J2OA 5FXWA 5A1LA 3MMKA 5FY7A 1IBIA 1X62A 3IXEB 3AVRA 5FP3A 1X63A 2CU8A 1RUTX 5LKTA 4BHWA 2L6ZC 2MIUA 1IMLA 3NIMA 2CURA 1V6GA 4HI9B 2MBVA 1G47A 2XJZA 1X6AA 2YPAC 4EZ4A 4HI8B 2DLOA 1B8TA 4UF0B 1CXXA 1WIGA 2XJYA 2XUEA 3AVSA 2O13A 5LKXA 4EYUA 4EZHA 4JCJA 1M3VA 4UF0A 1WYHA 5FY1A 2IYBE 2LXDA 2DARA 1U5SB 2L6YB 2EHEA 2DFYC 1X61A 2LZUA 5LKUA 3NISA 2EGQA 5LKZA 1X68A 2JTNA 1NYPA 2CUPA 3NIKA 2D8ZA 3NIHA 2O10A 2XQNT 5FXZA 3NIJA 1CTLA 2CORA 4ASKA 4KFZA 1QLIA 3NILA 2DJ7A 2CO8A 1A7IA 2CUQA 5FY0A 5FYMA 3NINA 1X3HA 2D8XA 3F6QB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2JTN A;  1NYP A;  2CUP A;  2KBX B;  1X4L A;  4JCJ A;  1M3V A;  1X64 A;  2D8Z A;  2L4Z A;  1WYH A;  2D8Y A;  2MBV A;  1G47 A;  2O10 A;  2XJZ A;  1J2O A;  2IYB E;  2LXD A;  2XQN T;  3MMK A;  2DAR A;  1U5S B;  1IBI A;  1X6A A;  2YPA C;  1CTL A;  2L6Y B;  1X62 A;  2EHE A;  2COR A;  3IXE B;  4HI8 B;  2DFY C;  2DLO A;  4KFZ A;  1B8T A;  1QLI A;  1X63 A;  1X61 A;  1CXX A;  1RUT X;  1WIG A;  2CU8 A;  2LZU A;  2XJY A;  2DJ7 A;  2L6Z C;  2MIU A;  2CO8 A;  1A7I A;  1IML A;  2CUQ A;  2EGQ A;  2O13 A;  1X3H A;  2CUR A;  1V6G A;  4HI9 B;  2D8X A;  3F6Q B;  1X68 A; 
#chains in the Genus database with same CATH topology
 2KBX B;  3ZPO A;  1X4L A;  5FXV A;  1X64 A;  2L4Z A;  2D8Y A;  5FXX A;  3ZLI A;  1J2O A;  5FXW A;  5A1L A;  3MMK A;  5FY7 A;  1IBI A;  1X62 A;  3IXE B;  3AVR A;  5FP3 A;  1X63 A;  2CU8 A;  1RUT X;  5LKT A;  4BHW A;  2L6Z C;  2MIU A;  1IML A;  3NIM A;  2CUR A;  1V6G A;  4HI9 B;  2MBV A;  1G47 A;  2XJZ A;  1X6A A;  2YPA C;  4EZ4 A;  4HI8 B;  2DLO A;  1B8T A;  4UF0 B;  1CXX A;  1WIG A;  2XJY A;  2XUE A;  3AVS A;  2O13 A;  5LKX A;  4EYU A;  4EZH A;  4JCJ A;  1M3V A;  4UF0 A;  1WYH A;  5FY1 A;  2IYB E;  2LXD A;  2DAR A;  1U5S B;  2L6Y B;  2EHE A;  2DFY C;  1X61 A;  2LZU A;  5LKU A;  3NIS A;  2EGQ A;  5LKZ A;  1X68 A;  2JTN A;  1NYP A;  2CUP A;  3NIK A;  2D8Z A;  3NIH A;  2O10 A;  2XQN T;  5FXZ A;  3NIJ A;  1CTL A;  2COR A;  4ASK A;  4KFZ A;  1QLI A;  3NIL A;  2DJ7 A;  2CO8 A;  1A7I A;  2CUQ A;  5FY0 A;  5FYM A;  3NIN A;  1X3H A;  2D8X A;  3F6Q B; 
#chains in the Genus database with same CATH homology
 2KBX B;  3ZPO A;  1X4L A;  5FXV A;  1X64 A;  2L4Z A;  2D8Y A;  5FXX A;  3ZLI A;  1J2O A;  5FXW A;  5A1L A;  3MMK A;  5FY7 A;  1IBI A;  1X62 A;  3IXE B;  3AVR A;  5FP3 A;  1X63 A;  2CU8 A;  1RUT X;  5LKT A;  4BHW A;  2L6Z C;  2MIU A;  1IML A;  3NIM A;  2CUR A;  1V6G A;  4HI9 B;  2MBV A;  1G47 A;  2XJZ A;  1X6A A;  2YPA C;  4EZ4 A;  4HI8 B;  2DLO A;  1B8T A;  4UF0 B;  1CXX A;  1WIG A;  2XJY A;  2XUE A;  3AVS A;  2O13 A;  5LKX A;  4EYU A;  4EZH A;  4JCJ A;  1M3V A;  4UF0 A;  1WYH A;  5FY1 A;  2IYB E;  2LXD A;  2DAR A;  1U5S B;  2L6Y B;  2EHE A;  2DFY C;  1X61 A;  2LZU A;  5LKU A;  3NIS A;  2EGQ A;  5LKZ A;  1X68 A;  2JTN A;  1NYP A;  2CUP A;  3NIK A;  2D8Z A;  3NIH A;  2O10 A;  2XQN T;  5FXZ A;  3NIJ A;  1CTL A;  2COR A;  4ASK A;  4KFZ A;  1QLI A;  3NIL A;  2DJ7 A;  2CO8 A;  1A7I A;  2CUQ A;  5FY0 A;  5FYM A;  3NIN A;  1X3H A;  2D8X A;  3F6Q B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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