2DDSA

Crystal structure of sphingomyelinase from bacillus cereus with cobalt ion
Total Genus 95
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
95
sequence length
299
structure length
299
Chain Sequence
NDTLKVMTHNVYMLSTNLYPNWGQTERADLIGAADYIKNQDVVILNEVFDNSASDRLLGNLKKEYPNQTAVLGRSSGSEWDKTLGNYSSSTPEDGGVAIVSKWPIAEKIQYVFAKGCGPDNLSNKGFVYTKIKKNDRFVHVIGTHLQAEDSMCGKTSPASVRTNQLKEIQDFIKNKNIPNNEYVLIGGDMNVNKINAENNNDSEYASMFKTLNASVPSYTGHTATWDATTNSIAKYNFPDSPAEYLDYIIASKDHANPSYIENKVLQPKSPQWTVTSWFQKYTYNDYSDHYPVEATISM
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title Structural Basis of the Sphingomyelin Phosphodiesterase Activity in Neutral Sphingomyelinase from Bacillus cereus.
pubmed doi rcsb
molecule tags Hydrolase
source organism Bacillus cereus
molecule keywords Sphingomyelin phosphodiesterase
total genus 95
structure length 299
sequence length 299
chains with identical sequence B, C, D
ec nomenclature ec 3.1.4.12: Sphingomyelin phosphodiesterase.
pdb deposition date 2006-02-02

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF03372 Exo_endo_phos Endonuclease/Exonuclease/phosphatase family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.60.10.10 Alpha Beta 4-Layer Sandwich Deoxyribonuclease I; Chain A Endonuclease/exonuclease/phosphatase 2ddsA00
5DFIA 3G2DA 3G00A 3G91A 3I5VA 4IEMA 4QHDA 1DEWA 5INKA 4QH9A 2A40B 5DFHA 4B5IA 5J8NA 1SI6X 3N9VA 1SR4B 1ZWXA 3G1KA 2VOAA 3W2YA 5DV2A 4B5FA 5J3SA 2UYRX 4B5HA 4C1RA 1DE9A 2EI9A 3MTCA 2F2FB 3NGNA 5J3PA 3GA6A 4A9CA 4QHEA 4B5GA 3MPRA 3G0RA 2V0RA 2DNJA 4L21A 5HT2A 4FPVA 5J42A 4JG3A 4GZ0A 1DE8A 2ISIA 4AWNA 2F1NA 2A3ZB 5J3ZA 3TEBA 4B5JA 5DFFA 2XSWA 1Y21A 4F1HA 3NGQA 4LNDA 2IMQX 5DG0A 3I48A 3G3YA 3G4TA 4L20A 2D1KB 5DV4A 4L1ZA 5INOA 3G2CA 1WDUA 4K6LF 4GEWA 3WCXA 3W3DB 5CFEA 2DDTA 4GYZA 1ATND 3G6SA 3K55A 4GZ2A 1YJHA 5INPA 4GZ1A 3DNIA 3G38A 1NTFA 2JC5A 5CFGA 4F1IA 1BIXA 4PUQA 4CMNA 1DNKA 5DFJA 3U8UA 4F1HB 2O3HA 1HD7A 1E9NA 5INQA 2A42B 4B5MA 5EWTA 2DDSA 3I46A 5A7JA 3NGOA 3NR8A 3CJCD 3G0AA 2O3CA 5INNA 3I41A 4RUWA 1VYBA 2DDRA 2JC4A 2J63A 3G8VA 4F1RA 2A41B 2V0SA 5INLA 4FVAA 5INMA 4L1YA 3G3CA 1AKOA 5A7IA 4CMLA 3FZIA 1I9ZA 3W2XA 3L1WA 1I9YA
chains in the Genus database with same CATH superfamily
5DFIA 3G2DA 3G00A 3G91A 3I5VA 4IEMA 4QHDA 1DEWA 5INKA 4QH9A 2A40B 5DFHA 4B5IA 5J8NA 1SI6X 3N9VA 1SR4B 1ZWXA 3G1KA 2VOAA 3W2YA 5DV2A 4B5FA 5J3SA 2UYRX 4B5HA 4C1RA 1DE9A 2EI9A 3MTCA 2F2FB 3NGNA 5J3PA 3GA6A 4A9CA 4QHEA 4B5GA 3MPRA 3G0RA 2V0RA 2DNJA 4L21A 5HT2A 4FPVA 5J42A 4JG3A 4GZ0A 1DE8A 2ISIA 4AWNA 2F1NA 2A3ZB 5J3ZA 3TEBA 4B5JA 5DFFA 2XSWA 1Y21A 4F1HA 3NGQA 4LNDA 2IMQX 5DG0A 3I48A 3G3YA 3G4TA 4L20A 2D1KB 5DV4A 4L1ZA 5INOA 3G2CA 1WDUA 4K6LF 4GEWA 3WCXA 3W3DB 5CFEA 2DDTA 4GYZA 1ATND 3G6SA 3K55A 4GZ2A 1YJHA 5INPA 4GZ1A 3DNIA 3G38A 1NTFA 2JC5A 5CFGA 4F1IA 1BIXA 4PUQA 4CMNA 1DNKA 5DFJA 3U8UA 4F1HB 2O3HA 1HD7A 1E9NA 5INQA 2A42B 4B5MA 5EWTA 2DDSA 3I46A 5A7JA 3NGOA 3NR8A 3CJCD 3G0AA 2O3CA 5INNA 3I41A 4RUWA 1VYBA 2DDRA 2JC4A 2J63A 3G8VA 4F1RA 2A41B 2V0SA 5INLA 4FVAA 5INMA 4L1YA 3G3CA 1AKOA 5A7IA 4CMLA 3FZIA 1I9ZA 3W2XA 3L1WA 1I9YA
chains in the Genus database with same CATH topology
5DFIA 3G2DA 3G00A 3G91A 3I5VA 4IEMA 4QHDA 1DEWA 5INKA 4QH9A 2A40B 5DFHA 4B5IA 5J8NA 1SI6X 3N9VA 1SR4B 1ZWXA 3G1KA 2VOAA 3W2YA 5DV2A 4B5FA 5J3SA 2UYRX 4B5HA 4C1RA 1DE9A 2EI9A 3MTCA 2F2FB 3NGNA 5J3PA 3GA6A 4A9CA 4QHEA 4B5GA 3MPRA 3G0RA 2V0RA 2DNJA 4L21A 5HT2A 4FPVA 5J42A 4JG3A 4GZ0A 1DE8A 2ISIA 4AWNA 2F1NA 2A3ZB 5J3ZA 3TEBA 4B5JA 5DFFA 2XSWA 1Y21A 4F1HA 3NGQA 4LNDA 2IMQX 5DG0A 3I48A 3G3YA 3G4TA 4L20A 2D1KB 5DV4A 4L1ZA 5INOA 3G2CA 1WDUA 4K6LF 4GEWA 3WCXA 3W3DB 5CFEA 2DDTA 4GYZA 1ATND 3G6SA 3K55A 4GZ2A 1YJHA 5INPA 4GZ1A 3DNIA 3G38A 1NTFA 2JC5A 5CFGA 4F1IA 1BIXA 4PUQA 4CMNA 1DNKA 5DFJA 3U8UA 4F1HB 2O3HA 1HD7A 1E9NA 5INQA 2A42B 4B5MA 5EWTA 2DDSA 3I46A 5A7JA 3NGOA 3NR8A 3CJCD 3G0AA 2O3CA 5INNA 3I41A 4RUWA 1VYBA 2DDRA 2JC4A 2J63A 3G8VA 4F1RA 2A41B 2V0SA 5INLA 4FVAA 5INMA 4L1YA 3G3CA 1AKOA 5A7IA 4CMLA 3FZIA 1I9ZA 3W2XA 3L1WA 1I9YA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5DFI A;  3G2D A;  3G00 A;  3G91 A;  3I5V A;  4IEM A;  4QHD A;  1DEW A;  5INK A;  4QH9 A;  2A40 B;  5DFH A;  4B5I A;  5J8N A;  1SI6 X;  3N9V A;  1SR4 B;  1ZWX A;  3G1K A;  2VOA A;  3W2Y A;  5DV2 A;  4B5F A;  5J3S A;  2UYR X;  4B5H A;  4C1R A;  1DE9 A;  2EI9 A;  3MTC A;  2F2F B;  3NGN A;  5J3P A;  3GA6 A;  4A9C A;  4QHE A;  4B5G A;  3MPR A;  3G0R A;  2V0R A;  2DNJ A;  4L21 A;  5HT2 A;  4FPV A;  5J42 A;  4JG3 A;  4GZ0 A;  1DE8 A;  2ISI A;  4AWN A;  2F1N A;  2A3Z B;  5J3Z A;  3TEB A;  4B5J A;  5DFF A;  2XSW A;  1Y21 A;  4F1H A;  3NGQ A;  4LND A;  2IMQ X;  5DG0 A;  3I48 A;  3G3Y A;  3G4T A;  4L20 A;  2D1K B;  5DV4 A;  4L1Z A;  5INO A;  3G2C A;  1WDU A;  4K6L F;  4GEW A;  3WCX A;  3W3D B;  5CFE A;  2DDT A;  4GYZ A;  1ATN D;  3G6S A;  3K55 A;  4GZ2 A;  1YJH A;  5INP A;  4GZ1 A;  3DNI A;  3G38 A;  1NTF A;  2JC5 A;  5CFG A;  4F1I A;  1BIX A;  4PUQ A;  4CMN A;  1DNK A;  5DFJ A;  3U8U A;  4F1H B;  2O3H A;  1HD7 A;  1E9N A;  5INQ A;  2A42 B;  4B5M A;  5EWT A;  2DDS A;  3I46 A;  5A7J A;  3NGO A;  3NR8 A;  3CJC D;  3G0A A;  2O3C A;  5INN A;  3I41 A;  4RUW A;  1VYB A;  2DDR A;  2JC4 A;  2J63 A;  3G8V A;  4F1R A;  2A41 B;  2V0S A;  5INL A;  4FVA A;  5INM A;  4L1Y A;  3G3C A;  1AKO A;  5A7I A;  4CML A;  3FZI A;  1I9Z A;  3W2X A;  3L1W A;  1I9Y A; 
#chains in the Genus database with same CATH topology
 5DFI A;  3G2D A;  3G00 A;  3G91 A;  3I5V A;  4IEM A;  4QHD A;  1DEW A;  5INK A;  4QH9 A;  2A40 B;  5DFH A;  4B5I A;  5J8N A;  1SI6 X;  3N9V A;  1SR4 B;  1ZWX A;  3G1K A;  2VOA A;  3W2Y A;  5DV2 A;  4B5F A;  5J3S A;  2UYR X;  4B5H A;  4C1R A;  1DE9 A;  2EI9 A;  3MTC A;  2F2F B;  3NGN A;  5J3P A;  3GA6 A;  4A9C A;  4QHE A;  4B5G A;  3MPR A;  3G0R A;  2V0R A;  2DNJ A;  4L21 A;  5HT2 A;  4FPV A;  5J42 A;  4JG3 A;  4GZ0 A;  1DE8 A;  2ISI A;  4AWN A;  2F1N A;  2A3Z B;  5J3Z A;  3TEB A;  4B5J A;  5DFF A;  2XSW A;  1Y21 A;  4F1H A;  3NGQ A;  4LND A;  2IMQ X;  5DG0 A;  3I48 A;  3G3Y A;  3G4T A;  4L20 A;  2D1K B;  5DV4 A;  4L1Z A;  5INO A;  3G2C A;  1WDU A;  4K6L F;  4GEW A;  3WCX A;  3W3D B;  5CFE A;  2DDT A;  4GYZ A;  1ATN D;  3G6S A;  3K55 A;  4GZ2 A;  1YJH A;  5INP A;  4GZ1 A;  3DNI A;  3G38 A;  1NTF A;  2JC5 A;  5CFG A;  4F1I A;  1BIX A;  4PUQ A;  4CMN A;  1DNK A;  5DFJ A;  3U8U A;  4F1H B;  2O3H A;  1HD7 A;  1E9N A;  5INQ A;  2A42 B;  4B5M A;  5EWT A;  2DDS A;  3I46 A;  5A7J A;  3NGO A;  3NR8 A;  3CJC D;  3G0A A;  2O3C A;  5INN A;  3I41 A;  4RUW A;  1VYB A;  2DDR A;  2JC4 A;  2J63 A;  3G8V A;  4F1R A;  2A41 B;  2V0S A;  5INL A;  4FVA A;  5INM A;  4L1Y A;  3G3C A;  1AKO A;  5A7I A;  4CML A;  3FZI A;  1I9Z A;  3W2X A;  3L1W A;  1I9Y A; 
#chains in the Genus database with same CATH homology
 5DFI A;  3G2D A;  3G00 A;  3G91 A;  3I5V A;  4IEM A;  4QHD A;  1DEW A;  5INK A;  4QH9 A;  2A40 B;  5DFH A;  4B5I A;  5J8N A;  1SI6 X;  3N9V A;  1SR4 B;  1ZWX A;  3G1K A;  2VOA A;  3W2Y A;  5DV2 A;  4B5F A;  5J3S A;  2UYR X;  4B5H A;  4C1R A;  1DE9 A;  2EI9 A;  3MTC A;  2F2F B;  3NGN A;  5J3P A;  3GA6 A;  4A9C A;  4QHE A;  4B5G A;  3MPR A;  3G0R A;  2V0R A;  2DNJ A;  4L21 A;  5HT2 A;  4FPV A;  5J42 A;  4JG3 A;  4GZ0 A;  1DE8 A;  2ISI A;  4AWN A;  2F1N A;  2A3Z B;  5J3Z A;  3TEB A;  4B5J A;  5DFF A;  2XSW A;  1Y21 A;  4F1H A;  3NGQ A;  4LND A;  2IMQ X;  5DG0 A;  3I48 A;  3G3Y A;  3G4T A;  4L20 A;  2D1K B;  5DV4 A;  4L1Z A;  5INO A;  3G2C A;  1WDU A;  4K6L F;  4GEW A;  3WCX A;  3W3D B;  5CFE A;  2DDT A;  4GYZ A;  1ATN D;  3G6S A;  3K55 A;  4GZ2 A;  1YJH A;  5INP A;  4GZ1 A;  3DNI A;  3G38 A;  1NTF A;  2JC5 A;  5CFG A;  4F1I A;  1BIX A;  4PUQ A;  4CMN A;  1DNK A;  5DFJ A;  3U8U A;  4F1H B;  2O3H A;  1HD7 A;  1E9N A;  5INQ A;  2A42 B;  4B5M A;  5EWT A;  2DDS A;  3I46 A;  5A7J A;  3NGO A;  3NR8 A;  3CJC D;  3G0A A;  2O3C A;  5INN A;  3I41 A;  4RUW A;  1VYB A;  2DDR A;  2JC4 A;  2J63 A;  3G8V A;  4F1R A;  2A41 B;  2V0S A;  5INL A;  4FVA A;  5INM A;  4L1Y A;  3G3C A;  1AKO A;  5A7I A;  4CML A;  3FZI A;  1I9Z A;  3W2X A;  3L1W A;  1I9Y A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...