2DOHX

The x-ray crystallographic structure of the angiogenesis inhibitor, angiostatin, bound a to a peptide from the group a streptococcal surface protein pam
Total Genus 42
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
42
sequence length
165
structure length
165
Chain Sequence
LSECKTGNGKNYRGTMSKTKNGITCQKWSSTSPHRPRFSPATHPSEGLEENYCRNPDNDPQGPWCYTTDPEKRYDYCDILECEEECMHCSGENYDGKISKTMSGLECQAWDSQSPHAHGYIPSKFPNKNLKKNYCRNPDRELRPWCFTTDPNKRWELCDIPRCTT
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Hydrolase
molecule keywords Angiostatin
publication title X-ray crystallographic structure of the angiogenesis inhibitor, angiostatin, bound to a peptide from the group A streptococcal surface protein PAM
pubmed doi rcsb
source organism Homo sapiens
total genus 42
structure length 165
sequence length 165
ec nomenclature ec 3.4.21.7: Plasmin.
pdb deposition date 2006-04-29

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
X PF00051 Kringle Kringle domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.40.20.10 Mainly Beta Beta Barrel Plasminogen Kringle 4 Plasminogen Kringle 4 2dohX00
3K65A 1NL1A 4HZHA 5CP9A 2QJ4A 1I5KA 5CT1A 1A0HA 3NXPA 5HPGA 4BVVA 2QJ2A 2DOIA 3SP8A 2I9BA 1PMKA 4BVDA 1B2IA 1NK1A 1JFNA 3BT1A 4BVWA 5CS1A 1KI0A 1GP9A 1PKRA 5CT3A 3U73A 1GMNA 1KIVA 5CS3A 3MKPA 2PK4A 4IUAA 4DURA 2I9AA 3LAQA 2FD6A 2L0SA 3HN4A 1PMLA 4A5TS 1GMOA 4CIKA 5CS5A 3E6PL 3KIVA 5CS9A 5CSQA 2PF2A 1CEBA 1HPJA 1HPKA 4BVCA 1PK2A 2FEBA 4D3CA 2PF1A 1CEAA 1NL2A 1I71A 1PK4A 3BT2A 2SPTA 1URKA 1KDUA 1TPKA 4O03A 1BHTA 2HPPP 2DOHX 2K4RA 4KIVA 4BV7A 2K51A 5COEA 4BV5A 2HPQP 1KRNA 2KNFA 5CT2A 4NZQA 2KJ4A
chains in the Genus database with same CATH superfamily
3K65A 1NL1A 4HZHA 5CP9A 2QJ4A 1I5KA 5CT1A 1A0HA 3NXPA 5HPGA 4BVVA 2QJ2A 2DOIA 3SP8A 2I9BA 1PMKA 4BVDA 1B2IA 1NK1A 1JFNA 3BT1A 4BVWA 5CS1A 1KI0A 1GP9A 1PKRA 5CT3A 3U73A 1GMNA 1KIVA 5CS3A 3MKPA 2PK4A 4IUAA 4DURA 2I9AA 3LAQA 2FD6A 2L0SA 3HN4A 1PMLA 4A5TS 1GMOA 4CIKA 5CS5A 3E6PL 3KIVA 5CS9A 5CSQA 2PF2A 1CEBA 1HPJA 1HPKA 4BVCA 1PK2A 2FEBA 4D3CA 2PF1A 1CEAA 1NL2A 1I71A 1PK4A 3BT2A 2SPTA 1URKA 1KDUA 1TPKA 4O03A 1BHTA 2HPPP 2DOHX 2K4RA 4KIVA 4BV7A 2K51A 5COEA 4BV5A 2HPQP 1KRNA 2KNFA 5CT2A 4NZQA 2KJ4A
chains in the Genus database with same CATH topology
3K65A 1NL1A 4HZHA 5CP9A 2QJ4A 1I5KA 5CT1A 1A0HA 3NXPA 5HPGA 4BVVA 2QJ2A 2DOIA 3SP8A 2I9BA 1PMKA 4BVDA 1B2IA 1NK1A 1JFNA 3BT1A 4BVWA 5CS1A 1KI0A 1GP9A 1PKRA 5CT3A 3U73A 1GMNA 1KIVA 5CS3A 3MKPA 2PK4A 4IUAA 4DURA 2I9AA 3LAQA 2FD6A 2L0SA 3HN4A 1PMLA 4A5TS 1GMOA 4CIKA 5CS5A 3E6PL 3KIVA 5CS9A 5CSQA 2PF2A 1CEBA 1HPJA 1HPKA 4BVCA 1PK2A 2FEBA 4D3CA 2PF1A 1CEAA 1NL2A 1I71A 1PK4A 3BT2A 2SPTA 1URKA 1KDUA 1TPKA 4O03A 1BHTA 2HPPP 2DOHX 2K4RA 4KIVA 4BV7A 2K51A 5COEA 4BV5A 2HPQP 1KRNA 2KNFA 5CT2A 4NZQA 2KJ4A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3K65 A;  1NL1 A;  4HZH A;  5CP9 A;  2QJ4 A;  1I5K A;  5CT1 A;  1A0H A;  3NXP A;  5HPG A;  4BVV A;  2QJ2 A;  2DOI A;  3SP8 A;  2I9B A;  1PMK A;  4BVD A;  1B2I A;  1NK1 A;  1JFN A;  3BT1 A;  4BVW A;  5CS1 A;  1KI0 A;  1GP9 A;  1PKR A;  5CT3 A;  3U73 A;  1GMN A;  1KIV A;  5CS3 A;  3MKP A;  2PK4 A;  4IUA A;  4DUR A;  2I9A A;  3LAQ A;  2FD6 A;  2L0S A;  3HN4 A;  1PML A;  4A5T S;  1GMO A;  4CIK A;  5CS5 A;  3E6P L;  3KIV A;  5CS9 A;  5CSQ A;  2PF2 A;  1CEB A;  1HPJ A;  1HPK A;  4BVC A;  1PK2 A;  2FEB A;  4D3C A;  2PF1 A;  1CEA A;  1NL2 A;  1I71 A;  1PK4 A;  3BT2 A;  2SPT A;  1URK A;  1KDU A;  1TPK A;  4O03 A;  1BHT A;  2HPP P;  2DOH X;  2K4R A;  4KIV A;  4BV7 A;  2K51 A;  5COE A;  4BV5 A;  2HPQ P;  1KRN A;  2KNF A;  5CT2 A;  4NZQ A;  2KJ4 A; 
#chains in the Genus database with same CATH topology
 3K65 A;  1NL1 A;  4HZH A;  5CP9 A;  2QJ4 A;  1I5K A;  5CT1 A;  1A0H A;  3NXP A;  5HPG A;  4BVV A;  2QJ2 A;  2DOI A;  3SP8 A;  2I9B A;  1PMK A;  4BVD A;  1B2I A;  1NK1 A;  1JFN A;  3BT1 A;  4BVW A;  5CS1 A;  1KI0 A;  1GP9 A;  1PKR A;  5CT3 A;  3U73 A;  1GMN A;  1KIV A;  5CS3 A;  3MKP A;  2PK4 A;  4IUA A;  4DUR A;  2I9A A;  3LAQ A;  2FD6 A;  2L0S A;  3HN4 A;  1PML A;  4A5T S;  1GMO A;  4CIK A;  5CS5 A;  3E6P L;  3KIV A;  5CS9 A;  5CSQ A;  2PF2 A;  1CEB A;  1HPJ A;  1HPK A;  4BVC A;  1PK2 A;  2FEB A;  4D3C A;  2PF1 A;  1CEA A;  1NL2 A;  1I71 A;  1PK4 A;  3BT2 A;  2SPT A;  1URK A;  1KDU A;  1TPK A;  4O03 A;  1BHT A;  2HPP P;  2DOH X;  2K4R A;  4KIV A;  4BV7 A;  2K51 A;  5COE A;  4BV5 A;  2HPQ P;  1KRN A;  2KNF A;  5CT2 A;  4NZQ A;  2KJ4 A; 
#chains in the Genus database with same CATH homology
 3K65 A;  1NL1 A;  4HZH A;  5CP9 A;  2QJ4 A;  1I5K A;  5CT1 A;  1A0H A;  3NXP A;  5HPG A;  4BVV A;  2QJ2 A;  2DOI A;  3SP8 A;  2I9B A;  1PMK A;  4BVD A;  1B2I A;  1NK1 A;  1JFN A;  3BT1 A;  4BVW A;  5CS1 A;  1KI0 A;  1GP9 A;  1PKR A;  5CT3 A;  3U73 A;  1GMN A;  1KIV A;  5CS3 A;  3MKP A;  2PK4 A;  4IUA A;  4DUR A;  2I9A A;  3LAQ A;  2FD6 A;  2L0S A;  3HN4 A;  1PML A;  4A5T S;  1GMO A;  4CIK A;  5CS5 A;  3E6P L;  3KIV A;  5CS9 A;  5CSQ A;  2PF2 A;  1CEB A;  1HPJ A;  1HPK A;  4BVC A;  1PK2 A;  2FEB A;  4D3C A;  2PF1 A;  1CEA A;  1NL2 A;  1I71 A;  1PK4 A;  3BT2 A;  2SPT A;  1URK A;  1KDU A;  1TPK A;  4O03 A;  1BHT A;  2HPP P;  2DOH X;  2K4R A;  4KIV A;  4BV7 A;  2K51 A;  5COE A;  4BV5 A;  2HPQ P;  1KRN A;  2KNF A;  5CT2 A;  4NZQ A;  2KJ4 A; 
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