2DOIA

The x-ray crystallographic structure of the angiogenesis inhibitor, angiostatin, bound to a peptide from the group a streptococcus protein pam
Total Genus 32
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
32
sequence length
164
structure length
164
Chain Sequence
LSECKTGNGKNYRGTMSKTKNGITCQKWSSTSPHRPRFSPATHPSEGLEENYCRNPDNDPQGPWCYTTDPEKRYDYCDILECEEECMHCSGENYDGKISKTMSGLECQAWDSQSPHAHGYIPSKFPNKNLKKNYCRNPDRELRPWCFTTDPNKRWELCDIPRCT
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
molecule tags Hydrolase
molecule keywords Angiostatin
publication title X-ray crystallographic structure of the angiogenesis inhibitor, angiostatin, bound to a peptide from the group A streptococcal surface protein PAM
pubmed doi rcsb
source organism Homo sapiens
total genus 32
structure length 164
sequence length 164
chains with identical sequence X
ec nomenclature ec 3.4.21.7: Plasmin.
pdb deposition date 2006-04-29

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00051 Kringle Kringle domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.40.20.10 Mainly Beta Beta Barrel Plasminogen Kringle 4 Plasminogen Kringle 4 2doiA00
2QJ4A 1PKRA 2SPTA 1CEBA 4O03A 1PK2A 5CS3A 2PF1A 4BVCA 2PF2A 2PK4A 5CS9A 5CS5A 3BT1A 4DURA 1A0HA 1KRNA 4KIVA 1PMLA 2K4RA 5CS1A 3MKPA 2HPPP 1BHTA 3SP8A 5CP9A 1NL2A 5CT2A 4A5TS 2FEBA 2I9AA 2L0SA 1NL1A 1NK1A 1KDUA 3K65A 5CSQA 4D3CA 2K51A 2KJ4A 4BV5A 1I5KA 1PK4A 3NXPA 1JFNA 4BV7A 1HPJA 3E6PL 4HZHA 2FD6A 1HPKA 1PMKA 3U73A 1B2IA 5CT1A 1CEAA 4BVVA 3LAQA 2QJ2A 1URKA 1GP9A 2I9BA 4IUAA 4BVWA 1GMNA 3KIVA 2HPQP 1GMOA 1KIVA 5COEA 3HN4A 2DOHX 5CT3A 2DOIA 1KI0A 4BVDA 4NZQA 3BT2A 2KNFA 1I71A 1TPKA 5HPGA 4CIKA
chains in the Genus database with same CATH superfamily
2QJ4A 1PKRA 2SPTA 1CEBA 4O03A 1PK2A 5CS3A 2PF1A 4BVCA 2PF2A 2PK4A 5CS9A 5CS5A 3BT1A 4DURA 1A0HA 1KRNA 4KIVA 1PMLA 2K4RA 5CS1A 3MKPA 2HPPP 1BHTA 3SP8A 5CP9A 1NL2A 5CT2A 4A5TS 2FEBA 2I9AA 2L0SA 1NL1A 1NK1A 1KDUA 3K65A 5CSQA 4D3CA 2K51A 2KJ4A 4BV5A 1I5KA 1PK4A 3NXPA 1JFNA 4BV7A 1HPJA 3E6PL 4HZHA 2FD6A 1HPKA 1PMKA 3U73A 1B2IA 5CT1A 1CEAA 4BVVA 3LAQA 2QJ2A 1URKA 1GP9A 2I9BA 4IUAA 4BVWA 1GMNA 3KIVA 2HPQP 1GMOA 1KIVA 5COEA 3HN4A 2DOHX 5CT3A 2DOIA 1KI0A 4BVDA 4NZQA 3BT2A 2KNFA 1I71A 1TPKA 5HPGA 4CIKA
chains in the Genus database with same CATH topology
2QJ4A 1PKRA 2SPTA 1CEBA 4O03A 1PK2A 5CS3A 2PF1A 4BVCA 2PF2A 2PK4A 5CS9A 5CS5A 3BT1A 4DURA 1A0HA 1KRNA 4KIVA 1PMLA 2K4RA 5CS1A 3MKPA 2HPPP 1BHTA 3SP8A 5CP9A 1NL2A 5CT2A 4A5TS 2FEBA 2I9AA 2L0SA 1NL1A 1NK1A 1KDUA 3K65A 5CSQA 4D3CA 2K51A 2KJ4A 4BV5A 1I5KA 1PK4A 3NXPA 1JFNA 4BV7A 1HPJA 3E6PL 4HZHA 2FD6A 1HPKA 1PMKA 3U73A 1B2IA 5CT1A 1CEAA 4BVVA 3LAQA 2QJ2A 1URKA 1GP9A 2I9BA 4IUAA 4BVWA 1GMNA 3KIVA 2HPQP 1GMOA 1KIVA 5COEA 3HN4A 2DOHX 5CT3A 2DOIA 1KI0A 4BVDA 4NZQA 3BT2A 2KNFA 1I71A 1TPKA 5HPGA 4CIKA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2QJ4 A;  1PKR A;  2SPT A;  1CEB A;  4O03 A;  1PK2 A;  5CS3 A;  2PF1 A;  4BVC A;  2PF2 A;  2PK4 A;  5CS9 A;  5CS5 A;  3BT1 A;  4DUR A;  1A0H A;  1KRN A;  4KIV A;  1PML A;  2K4R A;  5CS1 A;  3MKP A;  2HPP P;  1BHT A;  3SP8 A;  5CP9 A;  1NL2 A;  5CT2 A;  4A5T S;  2FEB A;  2I9A A;  2L0S A;  1NL1 A;  1NK1 A;  1KDU A;  3K65 A;  5CSQ A;  4D3C A;  2K51 A;  2KJ4 A;  4BV5 A;  1I5K A;  1PK4 A;  3NXP A;  1JFN A;  4BV7 A;  1HPJ A;  3E6P L;  4HZH A;  2FD6 A;  1HPK A;  1PMK A;  3U73 A;  1B2I A;  5CT1 A;  1CEA A;  4BVV A;  3LAQ A;  2QJ2 A;  1URK A;  1GP9 A;  2I9B A;  4IUA A;  4BVW A;  1GMN A;  3KIV A;  2HPQ P;  1GMO A;  1KIV A;  5COE A;  3HN4 A;  2DOH X;  5CT3 A;  2DOI A;  1KI0 A;  4BVD A;  4NZQ A;  3BT2 A;  2KNF A;  1I71 A;  1TPK A;  5HPG A;  4CIK A; 
#chains in the Genus database with same CATH topology
 2QJ4 A;  1PKR A;  2SPT A;  1CEB A;  4O03 A;  1PK2 A;  5CS3 A;  2PF1 A;  4BVC A;  2PF2 A;  2PK4 A;  5CS9 A;  5CS5 A;  3BT1 A;  4DUR A;  1A0H A;  1KRN A;  4KIV A;  1PML A;  2K4R A;  5CS1 A;  3MKP A;  2HPP P;  1BHT A;  3SP8 A;  5CP9 A;  1NL2 A;  5CT2 A;  4A5T S;  2FEB A;  2I9A A;  2L0S A;  1NL1 A;  1NK1 A;  1KDU A;  3K65 A;  5CSQ A;  4D3C A;  2K51 A;  2KJ4 A;  4BV5 A;  1I5K A;  1PK4 A;  3NXP A;  1JFN A;  4BV7 A;  1HPJ A;  3E6P L;  4HZH A;  2FD6 A;  1HPK A;  1PMK A;  3U73 A;  1B2I A;  5CT1 A;  1CEA A;  4BVV A;  3LAQ A;  2QJ2 A;  1URK A;  1GP9 A;  2I9B A;  4IUA A;  4BVW A;  1GMN A;  3KIV A;  2HPQ P;  1GMO A;  1KIV A;  5COE A;  3HN4 A;  2DOH X;  5CT3 A;  2DOI A;  1KI0 A;  4BVD A;  4NZQ A;  3BT2 A;  2KNF A;  1I71 A;  1TPK A;  5HPG A;  4CIK A; 
#chains in the Genus database with same CATH homology
 2QJ4 A;  1PKR A;  2SPT A;  1CEB A;  4O03 A;  1PK2 A;  5CS3 A;  2PF1 A;  4BVC A;  2PF2 A;  2PK4 A;  5CS9 A;  5CS5 A;  3BT1 A;  4DUR A;  1A0H A;  1KRN A;  4KIV A;  1PML A;  2K4R A;  5CS1 A;  3MKP A;  2HPP P;  1BHT A;  3SP8 A;  5CP9 A;  1NL2 A;  5CT2 A;  4A5T S;  2FEB A;  2I9A A;  2L0S A;  1NL1 A;  1NK1 A;  1KDU A;  3K65 A;  5CSQ A;  4D3C A;  2K51 A;  2KJ4 A;  4BV5 A;  1I5K A;  1PK4 A;  3NXP A;  1JFN A;  4BV7 A;  1HPJ A;  3E6P L;  4HZH A;  2FD6 A;  1HPK A;  1PMK A;  3U73 A;  1B2I A;  5CT1 A;  1CEA A;  4BVV A;  3LAQ A;  2QJ2 A;  1URK A;  1GP9 A;  2I9B A;  4IUA A;  4BVW A;  1GMN A;  3KIV A;  2HPQ P;  1GMO A;  1KIV A;  5COE A;  3HN4 A;  2DOH X;  5CT3 A;  2DOI A;  1KI0 A;  4BVD A;  4NZQ A;  3BT2 A;  2KNF A;  1I71 A;  1TPK A;  5HPG A;  4CIK A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...