2DRNA

Docking and dimerization domain (d/d) of the type ii-alpha regulatory subunity of protein kinase a (pka) in complex with a peptide from an a-kinase anchoring protein
Total Genus 13
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
13
sequence length
46
structure length
46
Chain Sequence
HMGHIQIPPGLTELLQGYTVEVLRQQPPDLVDFAVEYFTRLREARR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Transferase
molecule keywords cAMP-dependent protein kinase type II-alpha regulatory subun
publication title A novel mechanism of PKA anchoring revealed by solution structures of anchoring complexes.
pubmed doi rcsb
source organism Rattus norvegicus
total genus 13
structure length 46
sequence length 46
chains with identical sequence B
ec nomenclature ec 2.7.1.37: Transferred entry: 2.7.11.1, 2.7.11.8, 2.7.11.9, 2.7.11.10, 2.7.11.11,
pdb deposition date 2006-06-11

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02197 RIIa Regulatory subunit of type II PKA R-subunit
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.890.10 Mainly Alpha Up-down Bundle cAMP-dependent Protein Kinase, Chain A cAMP-dependent protein kinase regulatory subunit, dimerization-anchoring domain 2drnA00
1R2AA 4RIQA 4RT4A 2EZWA 4RTAA 2H9RA 5HVZA 2IZYA 4F9KA 1L6EA 3G36A 2DRNA 3IM4A 3IM3A 2KYGA 4ZP3A
chains in the Genus database with same CATH superfamily
4RIQA 3ACSA 2CBGA 3AFJA 2KNGA 2DRNA 3IM4A 2RQYA 3GWHA 3QFZA 4RT4A 4RTAA 2I15A 3PMIA 4F9KA 3S4CA 2CQTA 3IM3A 4ZP3A 3ACTA 3S4DA 3QG0A 3S4AA 3G36A 3RRSA 2CQSA 2KYGA 1R2AA 3RSYA 3S4BA 2EZWA 2CB9A 2H9RA 2OUTA 5HVZA 2IZYA 3QFYA 3QDEA 1L6EA 3UFEA 2K9QA
chains in the Genus database with same CATH topology
1R2AA 4RIQA 4RT4A 2EZWA 4RTAA 2H9RA 5HVZA 2IZYA 4F9KA 1L6EA 3G36A 2DRNA 3IM4A 3IM3A 2KYGA 4ZP3A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1R2A A;  4RIQ A;  4RT4 A;  2EZW A;  4RTA A;  2H9R A;  5HVZ A;  2IZY A;  4F9K A;  1L6E A;  3G36 A;  2DRN A;  3IM4 A;  3IM3 A;  2KYG A;  4ZP3 A; 
#chains in the Genus database with same CATH topology
 4RIQ A;  3ACS A;  2CBG A;  3AFJ A;  2KNG A;  2DRN A;  3IM4 A;  2RQY A;  3GWH A;  3QFZ A;  4RT4 A;  4RTA A;  2I15 A;  3PMI A;  4F9K A;  3S4C A;  2CQT A;  3IM3 A;  4ZP3 A;  3ACT A;  3S4D A;  3QG0 A;  3S4A A;  3G36 A;  3RRS A;  2CQS A;  2KYG A;  1R2A A;  3RSY A;  3S4B A;  2EZW A;  2CB9 A;  2H9R A;  2OUT A;  5HVZ A;  2IZY A;  3QFY A;  3QDE A;  1L6E A;  3UFE A;  2K9Q A; 
#chains in the Genus database with same CATH homology
 1R2A A;  4RIQ A;  4RT4 A;  2EZW A;  4RTA A;  2H9R A;  5HVZ A;  2IZY A;  4F9K A;  1L6E A;  3G36 A;  2DRN A;  3IM4 A;  3IM3 A;  2KYG A;  4ZP3 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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