2DSGA

Crystal structure of lys26 to arg mutant of diphthine synthase
Total Genus 81
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
81
sequence length
265
structure length
265
Chain Sequence
b'MVLYFIGLGLYDERDITVKGLEIAKRCDYVFAEFYTSLMAGTTLGRIQKLIGKEIRVLSREDVELNFENIVLPLAKENDVAFLTPGDPLVATTHAELRIRAKRAGVESYVIHAPSIYSAVGITGLHIYKFGKSATVAYPEGNWFPTSYYDVIKENAERGLHTLLFLDIKAEKRMYMTANEAMELLLKVEDMKKGGVFTDDTLVVVLARAGSLNPTIRAGYVKDLIREDFGDPPHILIVPGKLHIVEAEYLVEIAGAPREILRVNV'
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords diphthine synthase
publication title Crystal structure of diphthine synthase from Pyrococcus horikoshii OT3
rcsb
source organism Pyrococcus horikoshii
molecule tags Transferase
total genus 81
structure length 265
sequence length 265
chains with identical sequence B
ec nomenclature ec 2.1.1.98: Diphthine synthase.
pdb deposition date 2006-06-30

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00590 TP_methylase Tetrapyrrole (Corrin/Porphyrin) Methylases
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.950.10 Alpha Beta 2-Layer Sandwich Methyltransferase, Cobalt-precorrin-4 Transmethylase; Domain 2 Methyltransferase, Cobalt-precorrin-4 Transmethylase; Domain 2 2dsgA02
3.40.1010.10 Alpha Beta 3-Layer(aba) Sandwich Cobalt-precorrin-4 Transmethylase; domain 1 Cobalt-precorrin-4 Transmethylase; Domain 1 2dsgA01
2DXWA 2E17A 2E8QA 2EL2A 2DSIA 2EGSA 2EL3A 2E4RA 2YBOA 2P6LA 2HUXA 1PJTA 5HW4A 1WDEA 2DSGA 1VHVA 2EHCA 1VE2A 2HUTA 3I4TA 2E07A 3FFYA 1VA0A 2BB3A 2E8HA 2DSHA 2HUVA 2HUQA 2EEQA 2DXXA 2E0NA 3NUTA 2DXVA 2OWKA 2PB4A 2P5FA 2EK4A 2PB6A 2EMRA 3HH1A 2EMUA 2E7RA 2P6IA 2EK7A 2DV5A 3KWPA 2CBFA 2PCAA 1VCEA 2OWGA 2E15A 2DV7A 2NPNA 2EGBA 2E08A 1PJQA 2EL0A 2DEKA 2QBUA 1S4DA 2HR8A 2ELDA 1WNGA 3NDCA 2ZVCA 2PCIA 2OWUA 2DV4A 2ZVBA 2P6KA 3ND1A 2EHLA 4E16A 2EJJA 2EK3A 2EN5A 2PCMA 2OWFA 2Z6RA 2EH5A 3NEIA 2ENIA 2PCHA 3FQ6A 2ED3A 2EH2A 2EH4A 2EK2A 2EKAA 2E8RA 2PCKA 2P9DA 2P6DA 2OWVA 2PB5A 1WYZA 2P2XA 1CBFA 1PJSA 2E0KA 2EGLA 1V9AA 2ELEA 2YBQA 2EJKA 2E16A 2P5CA 2DV3A 2PCGA 2ED5A 2E4NA 2E8SA 2EJZA 2EL1A
chains in the Genus database with same CATH superfamily
2DXWA 2E17A 2E8QA 2EL2A 2DSIA 3SZOA 3UTDA 3UWMA 2EGSA 2EL3A 2E4RA 2YBOA 2P6LA 3T0GA 2HUXA 1PJTA 3UV7A 5HW4A 3KEMA 4H4EA 1WDEA 2DSGA 3SZLA 1VHVA 2EHCA 3UTCA 1VE2A 3ZGNA 2HUTA 3UV6A 3URKA 3I4TA 2E07A 3FFYA 1VA0A 2BB3A 2E8HA 4N7BA 2KYYA 4MV5A 2DSHA 2HUVA 2HUQA 2EEQA 2DXXA 2E0NA 3NUTA 2DXVA 2OWKA 2PB4A 3KELA 2P5FA 2EK4A 4H4CA 2PB6A 2EMRA 3KE8A 3HH1A 2EMUA 2E7RA 2P6IA 2EK7A 2DV5A 3KWPA 2CBFA 4MUXA 2PCAA 1VCEA 2OWGA 2E15A 2DV7A 2NPNA 2EGBA 2E08A 1PJQA 2EL0A 2DEKA 2QBUA 1S4DA 2HR8A 3SZUA 3KE9A 2ELDA 1WNGA 3NDCA 2ZVCA 2PCIA 3TIXB 2OWUA 3UV3A 3LMMA 2DV4A 2ZVBA 2P6KA 3ND1A 2EHLA 4E16A 2EJJA 2EK3A 2EN5A 2PCMA 2OWFA 2Z6RA 2EH5A 3NEIA 3ZGLA 2ENIA 3DNFA 2PCHA 3FQ6A 2ED3A 3KEFA 2EH2A 2EH4A 2EK2A 2EKAA 2E8RA 2PCKA 2P9DA 2P6DA 2OWVA 4MV0A 2PB5A 1WYZA 4EB3A 2P2XA 1CBFA 1PJSA 3F7TA 2E0KA 2EGLA 1V9AA 2ELEA 4H4DA 2YBQA 2EJKA 2E16A 2P5CA 4MUYA 3T0FA 2DV3A 2PCGA 2ED5A 2E4NA 2E8SA 2EJZA 2EL1A
chains in the Genus database with same CATH topology
2DXWA 2E17A 2E8QA 2EL2A 2DSIA 3SZOA 3UTDA 3UWMA 2EGSA 2EL3A 2E4RA 2YBOA 2P6LA 3T0GA 2HUXA 1PJTA 3UV7A 5HW4A 3KEMA 4H4EA 1WDEA 2DSGA 3SZLA 1VHVA 2EHCA 3UTCA 1VE2A 3ZGNA 2HUTA 3UV6A 3URKA 3I4TA 2E07A 3FFYA 1VA0A 2BB3A 2E8HA 4N7BA 2KYYA 4MV5A 2DSHA 2HUVA 2HUQA 2EEQA 2DXXA 2E0NA 3NUTA 2DXVA 2OWKA 2PB4A 3KELA 2P5FA 2EK4A 4H4CA 2PB6A 2EMRA 3KE8A 3HH1A 2EMUA 2E7RA 2P6IA 2EK7A 2DV5A 3KWPA 2CBFA 4MUXA 2PCAA 1VCEA 2OWGA 2E15A 2DV7A 2NPNA 2EGBA 2E08A 1PJQA 2EL0A 2DEKA 2QBUA 1S4DA 2HR8A 3SZUA 3KE9A 2ELDA 1WNGA 3NDCA 2ZVCA 2PCIA 3TIXB 2OWUA 3UV3A 3LMMA 2DV4A 2ZVBA 2P6KA 3ND1A 2EHLA 4E16A 2EJJA 2EK3A 2EN5A 2PCMA 2OWFA 2Z6RA 2EH5A 3NEIA 3ZGLA 2ENIA 3DNFA 2PCHA 3FQ6A 2ED3A 3KEFA 2EH2A 2EH4A 2EK2A 2EKAA 2E8RA 2PCKA 2P9DA 2P6DA 2OWVA 4MV0A 2PB5A 1WYZA 4EB3A 2P2XA 1CBFA 1PJSA 3F7TA 2E0KA 2EGLA 1V9AA 2ELEA 4H4DA 2YBQA 2EJKA 2E16A 2P5CA 4MUYA 3T0FA 2DV3A 2PCGA 2ED5A 2E4NA 2E8SA 2EJZA 2EL1A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2DXW A;  2E17 A;  2E8Q A;  2EL2 A;  2DSI A;  2EGS A;  2EL3 A;  2E4R A;  2YBO A;  2P6L A;  2HUX A;  1PJT A;  5HW4 A;  1WDE A;  2DSG A;  1VHV A;  2EHC A;  1VE2 A;  2HUT A;  3I4T A;  2E07 A;  3FFY A;  1VA0 A;  2BB3 A;  2E8H A;  2DSH A;  2HUV A;  2HUQ A;  2EEQ A;  2DXX A;  2E0N A;  3NUT A;  2DXV A;  2OWK A;  2PB4 A;  2P5F A;  2EK4 A;  2PB6 A;  2EMR A;  3HH1 A;  2EMU A;  2E7R A;  2P6I A;  2EK7 A;  2DV5 A;  3KWP A;  2CBF A;  2PCA A;  1VCE A;  2OWG A;  2E15 A;  2DV7 A;  2NPN A;  2EGB A;  2E08 A;  1PJQ A;  2EL0 A;  2DEK A;  2QBU A;  1S4D A;  2HR8 A;  2ELD A;  1WNG A;  3NDC A;  2ZVC A;  2PCI A;  2OWU A;  2DV4 A;  2ZVB A;  2P6K A;  3ND1 A;  2EHL A;  4E16 A;  2EJJ A;  2EK3 A;  2EN5 A;  2PCM A;  2OWF A;  2Z6R A;  2EH5 A;  3NEI A;  2ENI A;  2PCH A;  3FQ6 A;  2ED3 A;  2EH2 A;  2EH4 A;  2EK2 A;  2EKA A;  2E8R A;  2PCK A;  2P9D A;  2P6D A;  2OWV A;  2PB5 A;  1WYZ A;  2P2X A;  1CBF A;  1PJS A;  2E0K A;  2EGL A;  1V9A A;  2ELE A;  2YBQ A;  2EJK A;  2E16 A;  2P5C A;  2DV3 A;  2PCG A;  2ED5 A;  2E4N A;  2E8S A;  2EJZ A;  2EL1 A; 
#chains in the Genus database with same CATH topology
 2DXW A;  2E17 A;  2E8Q A;  2EL2 A;  2DSI A;  3SZO A;  3UTD A;  3UWM A;  2EGS A;  2EL3 A;  2E4R A;  2YBO A;  2P6L A;  3T0G A;  2HUX A;  1PJT A;  3UV7 A;  5HW4 A;  3KEM A;  4H4E A;  1WDE A;  2DSG A;  3SZL A;  1VHV A;  2EHC A;  3UTC A;  1VE2 A;  3ZGN A;  2HUT A;  3UV6 A;  3URK A;  3I4T A;  2E07 A;  3FFY A;  1VA0 A;  2BB3 A;  2E8H A;  4N7B A;  2KYY A;  4MV5 A;  2DSH A;  2HUV A;  2HUQ A;  2EEQ A;  2DXX A;  2E0N A;  3NUT A;  2DXV A;  2OWK A;  2PB4 A;  3KEL A;  2P5F A;  2EK4 A;  4H4C A;  2PB6 A;  2EMR A;  3KE8 A;  3HH1 A;  2EMU A;  2E7R A;  2P6I A;  2EK7 A;  2DV5 A;  3KWP A;  2CBF A;  4MUX A;  2PCA A;  1VCE A;  2OWG A;  2E15 A;  2DV7 A;  2NPN A;  2EGB A;  2E08 A;  1PJQ A;  2EL0 A;  2DEK A;  2QBU A;  1S4D A;  2HR8 A;  3SZU A;  3KE9 A;  2ELD A;  1WNG A;  3NDC A;  2ZVC A;  2PCI A;  3TIX B;  2OWU A;  3UV3 A;  3LMM A;  2DV4 A;  2ZVB A;  2P6K A;  3ND1 A;  2EHL A;  4E16 A;  2EJJ A;  2EK3 A;  2EN5 A;  2PCM A;  2OWF A;  2Z6R A;  2EH5 A;  3NEI A;  3ZGL A;  2ENI A;  3DNF A;  2PCH A;  3FQ6 A;  2ED3 A;  3KEF A;  2EH2 A;  2EH4 A;  2EK2 A;  2EKA A;  2E8R A;  2PCK A;  2P9D A;  2P6D A;  2OWV A;  4MV0 A;  2PB5 A;  1WYZ A;  4EB3 A;  2P2X A;  1CBF A;  1PJS A;  3F7T A;  2E0K A;  2EGL A;  1V9A A;  2ELE A;  4H4D A;  2YBQ A;  2EJK A;  2E16 A;  2P5C A;  4MUY A;  3T0F A;  2DV3 A;  2PCG A;  2ED5 A;  2E4N A;  2E8S A;  2EJZ A;  2EL1 A; 
#chains in the Genus database with same CATH homology
 2DXW A;  2E17 A;  2E8Q A;  2EL2 A;  2DSI A;  3SZO A;  3UTD A;  3UWM A;  2EGS A;  2EL3 A;  2E4R A;  2YBO A;  2P6L A;  3T0G A;  2HUX A;  1PJT A;  3UV7 A;  5HW4 A;  3KEM A;  4H4E A;  1WDE A;  2DSG A;  3SZL A;  1VHV A;  2EHC A;  3UTC A;  1VE2 A;  3ZGN A;  2HUT A;  3UV6 A;  3URK A;  3I4T A;  2E07 A;  3FFY A;  1VA0 A;  2BB3 A;  2E8H A;  4N7B A;  2KYY A;  4MV5 A;  2DSH A;  2HUV A;  2HUQ A;  2EEQ A;  2DXX A;  2E0N A;  3NUT A;  2DXV A;  2OWK A;  2PB4 A;  3KEL A;  2P5F A;  2EK4 A;  4H4C A;  2PB6 A;  2EMR A;  3KE8 A;  3HH1 A;  2EMU A;  2E7R A;  2P6I A;  2EK7 A;  2DV5 A;  3KWP A;  2CBF A;  4MUX A;  2PCA A;  1VCE A;  2OWG A;  2E15 A;  2DV7 A;  2NPN A;  2EGB A;  2E08 A;  1PJQ A;  2EL0 A;  2DEK A;  2QBU A;  1S4D A;  2HR8 A;  3SZU A;  3KE9 A;  2ELD A;  1WNG A;  3NDC A;  2ZVC A;  2PCI A;  3TIX B;  2OWU A;  3UV3 A;  3LMM A;  2DV4 A;  2ZVB A;  2P6K A;  3ND1 A;  2EHL A;  4E16 A;  2EJJ A;  2EK3 A;  2EN5 A;  2PCM A;  2OWF A;  2Z6R A;  2EH5 A;  3NEI A;  3ZGL A;  2ENI A;  3DNF A;  2PCH A;  3FQ6 A;  2ED3 A;  3KEF A;  2EH2 A;  2EH4 A;  2EK2 A;  2EKA A;  2E8R A;  2PCK A;  2P9D A;  2P6D A;  2OWV A;  4MV0 A;  2PB5 A;  1WYZ A;  4EB3 A;  2P2X A;  1CBF A;  1PJS A;  3F7T A;  2E0K A;  2EGL A;  1V9A A;  2ELE A;  4H4D A;  2YBQ A;  2EJK A;  2E16 A;  2P5C A;  4MUY A;  3T0F A;  2DV3 A;  2PCG A;  2ED5 A;  2E4N A;  2E8S A;  2EJZ A;  2EL1 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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