2DSHA

Crystal structure of lys26 to tyr mutant of diphthine synthase
Total Genus 82
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
82
sequence length
265
structure length
265
Chain Sequence
b'MVLYFIGLGLYDERDITVKGLEIAKYCDYVFAEFYTSLMAGTTLGRIQKLIGKEIRVLSREDVELNFENIVLPLAKENDVAFLTPGDPLVATTHAELRIRAKRAGVESYVIHAPSIYSAVGITGLHIYKFGKSATVAYPEGNWFPTSYYDVIKENAERGLHTLLFLDIKAEKRMYMTANEAMELLLKVEDMKKGGVFTDDTLVVVLARAGSLNPTIRAGYVKDLIREDFGDPPHILIVPGKLHIVEAEYLVEIAGAPREILRVNV'
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords diphthine synthase
publication title Crystal structure of diphthine synthase from Pyrococcus horikoshii OT3
rcsb
source organism Pyrococcus horikoshii
molecule tags Transferase
total genus 82
structure length 265
sequence length 265
chains with identical sequence B
ec nomenclature ec 2.1.1.98: Diphthine synthase.
pdb deposition date 2006-06-30

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00590 TP_methylase Tetrapyrrole (Corrin/Porphyrin) Methylases
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.950.10 Alpha Beta 2-Layer Sandwich Methyltransferase, Cobalt-precorrin-4 Transmethylase; Domain 2 Methyltransferase, Cobalt-precorrin-4 Transmethylase; Domain 2 2dshA02
3.40.1010.10 Alpha Beta 3-Layer(aba) Sandwich Cobalt-precorrin-4 Transmethylase; domain 1 Cobalt-precorrin-4 Transmethylase; Domain 1 2dshA01
2E8RA 2E4NA 2PCKA 2BB3A 2EHLA 2EJKA 2OWVA 2EK7A 2E0NA 2DXWA 1WYZA 1VE2A 2DSGA 2YBQA 2E17A 2DSIA 2DV7A 2HUXA 2NPNA 3FFYA 2P6LA 2PB4A 2OWGA 2DV4A 2PCAA 2P6DA 1VCEA 3ND1A 2DXXA 3NDCA 2ENIA 2Z6RA 4E16A 2PCHA 2E4RA 2EK2A 2PB6A 2YBOA 3KWPA 2E8QA 2E0KA 2EMRA 1PJSA 2HUVA 2EL1A 2E15A 1VHVA 2E16A 2QBUA 3NEIA 2DEKA 2P6IA 2EH2A 2EL3A 2EL0A 3HH1A 2E7RA 2ELEA 2ED5A 2DV3A 2E8HA 2OWUA 2DSHA 1PJQA 1WDEA 2DV5A 2ZVCA 2P6KA 2EEQA 2ZVBA 1V9AA 3NUTA 2EN5A 2EGLA 2EKAA 1VA0A 2ELDA 2ED3A 2PCIA 2EK3A 2EHCA 2EL2A 5HW4A 2EGBA 2P9DA 2HUQA 1S4DA 2EH5A 2P5FA 3FQ6A 2P5CA 2HR8A 2PCGA 2HUTA 2EJJA 1CBFA 2E08A 1PJTA 2P2XA 1WNGA 3I4TA 2E07A 2EGSA 2CBFA 2OWKA 2EJZA 2PB5A 2EH4A 2PCMA 2EMUA 2OWFA 2DXVA 2E8SA 2EK4A
chains in the Genus database with same CATH superfamily
2E8RA 2E4NA 3T0FA 2PCKA 3UV3A 2BB3A 2EHLA 2EJKA 2OWVA 2EK7A 4MV0A 2E0NA 2DXWA 3UWMA 1WYZA 1VE2A 2DSGA 2YBQA 2E17A 3F7TA 4MV5A 3UTDA 3KE8A 2DSIA 2DV7A 4MUXA 2HUXA 4H4DA 2NPNA 3FFYA 2P6LA 2PB4A 2OWGA 2DV4A 2PCAA 2P6DA 1VCEA 3UTCA 3ND1A 2DXXA 3NDCA 2ENIA 2Z6RA 4E16A 2PCHA 2E4RA 2EK2A 2PB6A 2YBOA 3KWPA 2E8QA 3TIXB 2E0KA 2EMRA 1PJSA 2HUVA 2EL1A 2E15A 1VHVA 2E16A 2QBUA 3NEIA 2DEKA 2P6IA 3T0GA 2EH2A 2EL3A 2EL0A 3HH1A 2E7RA 2ELEA 2ED5A 2DV3A 3ZGNA 3UV7A 2E8HA 3URKA 2OWUA 2DSHA 1PJQA 1WDEA 2DV5A 2ZVCA 2P6KA 2EEQA 2ZVBA 1V9AA 3NUTA 2EN5A 3ZGLA 2EGLA 2EKAA 1VA0A 2ELDA 2ED3A 2PCIA 2EK3A 2EHCA 2EL2A 3SZOA 4EB3A 5HW4A 3KEMA 2EGBA 2P9DA 3SZUA 2HUQA 1S4DA 3DNFA 2EH5A 2P5FA 3KELA 3FQ6A 3LMMA 2P5CA 2HR8A 2PCGA 2HUTA 2EJJA 1CBFA 2E08A 1PJTA 2P2XA 1WNGA 4H4CA 3I4TA 4H4EA 2E07A 2EGSA 3KE9A 2KYYA 2CBFA 2OWKA 2EJZA 2PB5A 3KEFA 2EH4A 3SZLA 3UV6A 2PCMA 2EMUA 2OWFA 4MUYA 2DXVA 2E8SA 2EK4A 4N7BA
chains in the Genus database with same CATH topology
2E8RA 2E4NA 3T0FA 2PCKA 3UV3A 2BB3A 2EHLA 2EJKA 2OWVA 2EK7A 4MV0A 2E0NA 2DXWA 3UWMA 1WYZA 1VE2A 2DSGA 2YBQA 2E17A 3F7TA 4MV5A 3UTDA 3KE8A 2DSIA 2DV7A 4MUXA 2HUXA 4H4DA 2NPNA 3FFYA 2P6LA 2PB4A 2OWGA 2DV4A 2PCAA 2P6DA 1VCEA 3UTCA 3ND1A 2DXXA 3NDCA 2ENIA 2Z6RA 4E16A 2PCHA 2E4RA 2EK2A 2PB6A 2YBOA 3KWPA 2E8QA 3TIXB 2E0KA 2EMRA 1PJSA 2HUVA 2EL1A 2E15A 1VHVA 2E16A 2QBUA 3NEIA 2DEKA 2P6IA 3T0GA 2EH2A 2EL3A 2EL0A 3HH1A 2E7RA 2ELEA 2ED5A 2DV3A 3ZGNA 3UV7A 2E8HA 3URKA 2OWUA 2DSHA 1PJQA 1WDEA 2DV5A 2ZVCA 2P6KA 2EEQA 2ZVBA 1V9AA 3NUTA 2EN5A 3ZGLA 2EGLA 2EKAA 1VA0A 2ELDA 2ED3A 2PCIA 2EK3A 2EHCA 2EL2A 3SZOA 4EB3A 5HW4A 3KEMA 2EGBA 2P9DA 3SZUA 2HUQA 1S4DA 3DNFA 2EH5A 2P5FA 3KELA 3FQ6A 3LMMA 2P5CA 2HR8A 2PCGA 2HUTA 2EJJA 1CBFA 2E08A 1PJTA 2P2XA 1WNGA 4H4CA 3I4TA 4H4EA 2E07A 2EGSA 3KE9A 2KYYA 2CBFA 2OWKA 2EJZA 2PB5A 3KEFA 2EH4A 3SZLA 3UV6A 2PCMA 2EMUA 2OWFA 4MUYA 2DXVA 2E8SA 2EK4A 4N7BA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2E8R A;  2E4N A;  2PCK A;  2BB3 A;  2EHL A;  2EJK A;  2OWV A;  2EK7 A;  2E0N A;  2DXW A;  1WYZ A;  1VE2 A;  2DSG A;  2YBQ A;  2E17 A;  2DSI A;  2DV7 A;  2HUX A;  2NPN A;  3FFY A;  2P6L A;  2PB4 A;  2OWG A;  2DV4 A;  2PCA A;  2P6D A;  1VCE A;  3ND1 A;  2DXX A;  3NDC A;  2ENI A;  2Z6R A;  4E16 A;  2PCH A;  2E4R A;  2EK2 A;  2PB6 A;  2YBO A;  3KWP A;  2E8Q A;  2E0K A;  2EMR A;  1PJS A;  2HUV A;  2EL1 A;  2E15 A;  1VHV A;  2E16 A;  2QBU A;  3NEI A;  2DEK A;  2P6I A;  2EH2 A;  2EL3 A;  2EL0 A;  3HH1 A;  2E7R A;  2ELE A;  2ED5 A;  2DV3 A;  2E8H A;  2OWU A;  2DSH A;  1PJQ A;  1WDE A;  2DV5 A;  2ZVC A;  2P6K A;  2EEQ A;  2ZVB A;  1V9A A;  3NUT A;  2EN5 A;  2EGL A;  2EKA A;  1VA0 A;  2ELD A;  2ED3 A;  2PCI A;  2EK3 A;  2EHC A;  2EL2 A;  5HW4 A;  2EGB A;  2P9D A;  2HUQ A;  1S4D A;  2EH5 A;  2P5F A;  3FQ6 A;  2P5C A;  2HR8 A;  2PCG A;  2HUT A;  2EJJ A;  1CBF A;  2E08 A;  1PJT A;  2P2X A;  1WNG A;  3I4T A;  2E07 A;  2EGS A;  2CBF A;  2OWK A;  2EJZ A;  2PB5 A;  2EH4 A;  2PCM A;  2EMU A;  2OWF A;  2DXV A;  2E8S A;  2EK4 A; 
#chains in the Genus database with same CATH topology
 2E8R A;  2E4N A;  3T0F A;  2PCK A;  3UV3 A;  2BB3 A;  2EHL A;  2EJK A;  2OWV A;  2EK7 A;  4MV0 A;  2E0N A;  2DXW A;  3UWM A;  1WYZ A;  1VE2 A;  2DSG A;  2YBQ A;  2E17 A;  3F7T A;  4MV5 A;  3UTD A;  3KE8 A;  2DSI A;  2DV7 A;  4MUX A;  2HUX A;  4H4D A;  2NPN A;  3FFY A;  2P6L A;  2PB4 A;  2OWG A;  2DV4 A;  2PCA A;  2P6D A;  1VCE A;  3UTC A;  3ND1 A;  2DXX A;  3NDC A;  2ENI A;  2Z6R A;  4E16 A;  2PCH A;  2E4R A;  2EK2 A;  2PB6 A;  2YBO A;  3KWP A;  2E8Q A;  3TIX B;  2E0K A;  2EMR A;  1PJS A;  2HUV A;  2EL1 A;  2E15 A;  1VHV A;  2E16 A;  2QBU A;  3NEI A;  2DEK A;  2P6I A;  3T0G A;  2EH2 A;  2EL3 A;  2EL0 A;  3HH1 A;  2E7R A;  2ELE A;  2ED5 A;  2DV3 A;  3ZGN A;  3UV7 A;  2E8H A;  3URK A;  2OWU A;  2DSH A;  1PJQ A;  1WDE A;  2DV5 A;  2ZVC A;  2P6K A;  2EEQ A;  2ZVB A;  1V9A A;  3NUT A;  2EN5 A;  3ZGL A;  2EGL A;  2EKA A;  1VA0 A;  2ELD A;  2ED3 A;  2PCI A;  2EK3 A;  2EHC A;  2EL2 A;  3SZO A;  4EB3 A;  5HW4 A;  3KEM A;  2EGB A;  2P9D A;  3SZU A;  2HUQ A;  1S4D A;  3DNF A;  2EH5 A;  2P5F A;  3KEL A;  3FQ6 A;  3LMM A;  2P5C A;  2HR8 A;  2PCG A;  2HUT A;  2EJJ A;  1CBF A;  2E08 A;  1PJT A;  2P2X A;  1WNG A;  4H4C A;  3I4T A;  4H4E A;  2E07 A;  2EGS A;  3KE9 A;  2KYY A;  2CBF A;  2OWK A;  2EJZ A;  2PB5 A;  3KEF A;  2EH4 A;  3SZL A;  3UV6 A;  2PCM A;  2EMU A;  2OWF A;  4MUY A;  2DXV A;  2E8S A;  2EK4 A;  4N7B A; 
#chains in the Genus database with same CATH homology
 2E8R A;  2E4N A;  3T0F A;  2PCK A;  3UV3 A;  2BB3 A;  2EHL A;  2EJK A;  2OWV A;  2EK7 A;  4MV0 A;  2E0N A;  2DXW A;  3UWM A;  1WYZ A;  1VE2 A;  2DSG A;  2YBQ A;  2E17 A;  3F7T A;  4MV5 A;  3UTD A;  3KE8 A;  2DSI A;  2DV7 A;  4MUX A;  2HUX A;  4H4D A;  2NPN A;  3FFY A;  2P6L A;  2PB4 A;  2OWG A;  2DV4 A;  2PCA A;  2P6D A;  1VCE A;  3UTC A;  3ND1 A;  2DXX A;  3NDC A;  2ENI A;  2Z6R A;  4E16 A;  2PCH A;  2E4R A;  2EK2 A;  2PB6 A;  2YBO A;  3KWP A;  2E8Q A;  3TIX B;  2E0K A;  2EMR A;  1PJS A;  2HUV A;  2EL1 A;  2E15 A;  1VHV A;  2E16 A;  2QBU A;  3NEI A;  2DEK A;  2P6I A;  3T0G A;  2EH2 A;  2EL3 A;  2EL0 A;  3HH1 A;  2E7R A;  2ELE A;  2ED5 A;  2DV3 A;  3ZGN A;  3UV7 A;  2E8H A;  3URK A;  2OWU A;  2DSH A;  1PJQ A;  1WDE A;  2DV5 A;  2ZVC A;  2P6K A;  2EEQ A;  2ZVB A;  1V9A A;  3NUT A;  2EN5 A;  3ZGL A;  2EGL A;  2EKA A;  1VA0 A;  2ELD A;  2ED3 A;  2PCI A;  2EK3 A;  2EHC A;  2EL2 A;  3SZO A;  4EB3 A;  5HW4 A;  3KEM A;  2EGB A;  2P9D A;  3SZU A;  2HUQ A;  1S4D A;  3DNF A;  2EH5 A;  2P5F A;  3KEL A;  3FQ6 A;  3LMM A;  2P5C A;  2HR8 A;  2PCG A;  2HUT A;  2EJJ A;  1CBF A;  2E08 A;  1PJT A;  2P2X A;  1WNG A;  4H4C A;  3I4T A;  4H4E A;  2E07 A;  2EGS A;  3KE9 A;  2KYY A;  2CBF A;  2OWK A;  2EJZ A;  2PB5 A;  3KEF A;  2EH4 A;  3SZL A;  3UV6 A;  2PCM A;  2EMU A;  2OWF A;  4MUY A;  2DXV A;  2E8S A;  2EK4 A;  4N7B A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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