2DSIA

Crystal structure of glu171 to arg mutant of diphthine synthase
Total Genus 81
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
81
sequence length
265
structure length
265
Chain Sequence
b'MVLYFIGLGLYDERDITVKGLEIAKKCDYVFAEFYTSLMAGTTLGRIQKLIGKEIRVLSREDVELNFENIVLPLAKENDVAFLTPGDPLVATTHAELRIRAKRAGVESYVIHAPSIYSAVGITGLHIYKFGKSATVAYPEGNWFPTSYYDVIKENAERGLHTLLFLDIKARKRMYMTANEAMELLLKVEDMKKGGVFTDDTLVVVLARAGSLNPTIRAGYVKDLIREDFGDPPHILIVPGKLHIVEAEYLVEIAGAPREILRVNV'
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords diphthine synthase
publication title Crystal structure of diphthine synthase from Pyrococcus horikoshii OT3
rcsb
source organism Pyrococcus horikoshii
molecule tags Transferase
total genus 81
structure length 265
sequence length 265
chains with identical sequence B
ec nomenclature ec 2.1.1.98: Diphthine synthase.
pdb deposition date 2006-06-30

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00590 TP_methylase Tetrapyrrole (Corrin/Porphyrin) Methylases
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.950.10 Alpha Beta 2-Layer Sandwich Methyltransferase, Cobalt-precorrin-4 Transmethylase; Domain 2 Methyltransferase, Cobalt-precorrin-4 Transmethylase; Domain 2 2dsiA02
3.40.1010.10 Alpha Beta 3-Layer(aba) Sandwich Cobalt-precorrin-4 Transmethylase; domain 1 Cobalt-precorrin-4 Transmethylase; Domain 1 2dsiA01
2E07A 2EH4A 2EK4A 3FQ6A 2EGBA 2EEQA 2ELDA 2DSGA 2E0NA 2P9DA 1S4DA 3FFYA 2EHCA 4E16A 2EJKA 2DV4A 2DV5A 2E08A 3I4TA 2E8HA 2PCGA 2EL1A 3HH1A 2ZVCA 2DV7A 2HUVA 2E8SA 2EGSA 2E15A 2NPNA 3NEIA 2DXXA 2OWFA 2PCKA 2DXWA 1WNGA 2EN5A 2ED3A 1VE2A 2E8RA 2EH2A 2EL0A 2PB4A 2EJZA 1VHVA 2E4RA 2DXVA 2YBQA 5HW4A 2E17A 3KWPA 2PCMA 2DEKA 1CBFA 2P6DA 2P6IA 2PCHA 1PJTA 2DV3A 1VCEA 2PB5A 2CBFA 2P6KA 2OWUA 2E4NA 2EK7A 3NUTA 2DSHA 2HR8A 2EL2A 1WDEA 2P5CA 1WYZA 2EK2A 1V9AA 2OWGA 1VA0A 2Z6RA 2P6LA 2EJJA 2PCIA 2HUXA 2OWKA 2EMUA 2ELEA 2ED5A 2EK3A 2ZVBA 2E16A 2EL3A 2E8QA 2HUQA 2EMRA 2EHLA 2BB3A 2DSIA 2ENIA 2HUTA 2P2XA 2QBUA 1PJSA 2YBOA 2OWVA 2EKAA 2E0KA 2P5FA 3NDCA 2PB6A 2E7RA 2PCAA 1PJQA 3ND1A 2EH5A 2EGLA
chains in the Genus database with same CATH superfamily
3UTCA 2E07A 2EH4A 2EK4A 3FQ6A 2EGBA 2EEQA 2ELDA 4MV5A 2DSGA 2E0NA 2P9DA 1S4DA 3FFYA 2EHCA 4E16A 3SZLA 3SZOA 3T0GA 2EJKA 2DV4A 2DV5A 2E08A 3I4TA 2E8HA 2PCGA 2EL1A 3HH1A 2ZVCA 2DV7A 3KEMA 3UV7A 3KELA 2HUVA 2E8SA 2EGSA 2E15A 2NPNA 3NEIA 3LMMA 2DXXA 2OWFA 2PCKA 3ZGNA 2DXWA 1WNGA 2EN5A 2ED3A 1VE2A 2E8RA 3KE9A 2EH2A 2EL0A 4EB3A 2PB4A 2EJZA 1VHVA 2E4RA 2DXVA 2YBQA 5HW4A 4H4DA 2E17A 3KWPA 2PCMA 2DEKA 1CBFA 2P6DA 2P6IA 4MUYA 2PCHA 1PJTA 2DV3A 3UWMA 1VCEA 2PB5A 4N7BA 2CBFA 2P6KA 2OWUA 3UTDA 2E4NA 2EK7A 3NUTA 2DSHA 2HR8A 2EL2A 1WDEA 2P5CA 3SZUA 1WYZA 2EK2A 3T0FA 1V9AA 2OWGA 1VA0A 3UV3A 4MV0A 2Z6RA 2P6LA 2EJJA 4H4CA 2PCIA 2HUXA 2OWKA 2EMUA 2ELEA 2ED5A 2EK3A 2ZVBA 2E16A 2EL3A 2E8QA 2HUQA 2EMRA 2EHLA 2BB3A 2DSIA 2ENIA 2HUTA 2P2XA 2QBUA 1PJSA 3TIXB 2YBOA 2OWVA 3KEFA 2EKAA 2E0KA 2P5FA 3NDCA 2PB6A 3URKA 3KE8A 3DNFA 3UV6A 2E7RA 3ZGLA 4H4EA 3F7TA 2PCAA 1PJQA 3ND1A 4MUXA 2EH5A 2KYYA 2EGLA
chains in the Genus database with same CATH topology
3UTCA 2E07A 2EH4A 2EK4A 3FQ6A 2EGBA 2EEQA 2ELDA 4MV5A 2DSGA 2E0NA 2P9DA 1S4DA 3FFYA 2EHCA 4E16A 3SZLA 3SZOA 3T0GA 2EJKA 2DV4A 2DV5A 2E08A 3I4TA 2E8HA 2PCGA 2EL1A 3HH1A 2ZVCA 2DV7A 3KEMA 3UV7A 3KELA 2HUVA 2E8SA 2EGSA 2E15A 2NPNA 3NEIA 3LMMA 2DXXA 2OWFA 2PCKA 3ZGNA 2DXWA 1WNGA 2EN5A 2ED3A 1VE2A 2E8RA 3KE9A 2EH2A 2EL0A 4EB3A 2PB4A 2EJZA 1VHVA 2E4RA 2DXVA 2YBQA 5HW4A 4H4DA 2E17A 3KWPA 2PCMA 2DEKA 1CBFA 2P6DA 2P6IA 4MUYA 2PCHA 1PJTA 2DV3A 3UWMA 1VCEA 2PB5A 4N7BA 2CBFA 2P6KA 2OWUA 3UTDA 2E4NA 2EK7A 3NUTA 2DSHA 2HR8A 2EL2A 1WDEA 2P5CA 3SZUA 1WYZA 2EK2A 3T0FA 1V9AA 2OWGA 1VA0A 3UV3A 4MV0A 2Z6RA 2P6LA 2EJJA 4H4CA 2PCIA 2HUXA 2OWKA 2EMUA 2ELEA 2ED5A 2EK3A 2ZVBA 2E16A 2EL3A 2E8QA 2HUQA 2EMRA 2EHLA 2BB3A 2DSIA 2ENIA 2HUTA 2P2XA 2QBUA 1PJSA 3TIXB 2YBOA 2OWVA 3KEFA 2EKAA 2E0KA 2P5FA 3NDCA 2PB6A 3URKA 3KE8A 3DNFA 3UV6A 2E7RA 3ZGLA 4H4EA 3F7TA 2PCAA 1PJQA 3ND1A 4MUXA 2EH5A 2KYYA 2EGLA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2E07 A;  2EH4 A;  2EK4 A;  3FQ6 A;  2EGB A;  2EEQ A;  2ELD A;  2DSG A;  2E0N A;  2P9D A;  1S4D A;  3FFY A;  2EHC A;  4E16 A;  2EJK A;  2DV4 A;  2DV5 A;  2E08 A;  3I4T A;  2E8H A;  2PCG A;  2EL1 A;  3HH1 A;  2ZVC A;  2DV7 A;  2HUV A;  2E8S A;  2EGS A;  2E15 A;  2NPN A;  3NEI A;  2DXX A;  2OWF A;  2PCK A;  2DXW A;  1WNG A;  2EN5 A;  2ED3 A;  1VE2 A;  2E8R A;  2EH2 A;  2EL0 A;  2PB4 A;  2EJZ A;  1VHV A;  2E4R A;  2DXV A;  2YBQ A;  5HW4 A;  2E17 A;  3KWP A;  2PCM A;  2DEK A;  1CBF A;  2P6D A;  2P6I A;  2PCH A;  1PJT A;  2DV3 A;  1VCE A;  2PB5 A;  2CBF A;  2P6K A;  2OWU A;  2E4N A;  2EK7 A;  3NUT A;  2DSH A;  2HR8 A;  2EL2 A;  1WDE A;  2P5C A;  1WYZ A;  2EK2 A;  1V9A A;  2OWG A;  1VA0 A;  2Z6R A;  2P6L A;  2EJJ A;  2PCI A;  2HUX A;  2OWK A;  2EMU A;  2ELE A;  2ED5 A;  2EK3 A;  2ZVB A;  2E16 A;  2EL3 A;  2E8Q A;  2HUQ A;  2EMR A;  2EHL A;  2BB3 A;  2DSI A;  2ENI A;  2HUT A;  2P2X A;  2QBU A;  1PJS A;  2YBO A;  2OWV A;  2EKA A;  2E0K A;  2P5F A;  3NDC A;  2PB6 A;  2E7R A;  2PCA A;  1PJQ A;  3ND1 A;  2EH5 A;  2EGL A; 
#chains in the Genus database with same CATH topology
 3UTC A;  2E07 A;  2EH4 A;  2EK4 A;  3FQ6 A;  2EGB A;  2EEQ A;  2ELD A;  4MV5 A;  2DSG A;  2E0N A;  2P9D A;  1S4D A;  3FFY A;  2EHC A;  4E16 A;  3SZL A;  3SZO A;  3T0G A;  2EJK A;  2DV4 A;  2DV5 A;  2E08 A;  3I4T A;  2E8H A;  2PCG A;  2EL1 A;  3HH1 A;  2ZVC A;  2DV7 A;  3KEM A;  3UV7 A;  3KEL A;  2HUV A;  2E8S A;  2EGS A;  2E15 A;  2NPN A;  3NEI A;  3LMM A;  2DXX A;  2OWF A;  2PCK A;  3ZGN A;  2DXW A;  1WNG A;  2EN5 A;  2ED3 A;  1VE2 A;  2E8R A;  3KE9 A;  2EH2 A;  2EL0 A;  4EB3 A;  2PB4 A;  2EJZ A;  1VHV A;  2E4R A;  2DXV A;  2YBQ A;  5HW4 A;  4H4D A;  2E17 A;  3KWP A;  2PCM A;  2DEK A;  1CBF A;  2P6D A;  2P6I A;  4MUY A;  2PCH A;  1PJT A;  2DV3 A;  3UWM A;  1VCE A;  2PB5 A;  4N7B A;  2CBF A;  2P6K A;  2OWU A;  3UTD A;  2E4N A;  2EK7 A;  3NUT A;  2DSH A;  2HR8 A;  2EL2 A;  1WDE A;  2P5C A;  3SZU A;  1WYZ A;  2EK2 A;  3T0F A;  1V9A A;  2OWG A;  1VA0 A;  3UV3 A;  4MV0 A;  2Z6R A;  2P6L A;  2EJJ A;  4H4C A;  2PCI A;  2HUX A;  2OWK A;  2EMU A;  2ELE A;  2ED5 A;  2EK3 A;  2ZVB A;  2E16 A;  2EL3 A;  2E8Q A;  2HUQ A;  2EMR A;  2EHL A;  2BB3 A;  2DSI A;  2ENI A;  2HUT A;  2P2X A;  2QBU A;  1PJS A;  3TIX B;  2YBO A;  2OWV A;  3KEF A;  2EKA A;  2E0K A;  2P5F A;  3NDC A;  2PB6 A;  3URK A;  3KE8 A;  3DNF A;  3UV6 A;  2E7R A;  3ZGL A;  4H4E A;  3F7T A;  2PCA A;  1PJQ A;  3ND1 A;  4MUX A;  2EH5 A;  2KYY A;  2EGL A; 
#chains in the Genus database with same CATH homology
 3UTC A;  2E07 A;  2EH4 A;  2EK4 A;  3FQ6 A;  2EGB A;  2EEQ A;  2ELD A;  4MV5 A;  2DSG A;  2E0N A;  2P9D A;  1S4D A;  3FFY A;  2EHC A;  4E16 A;  3SZL A;  3SZO A;  3T0G A;  2EJK A;  2DV4 A;  2DV5 A;  2E08 A;  3I4T A;  2E8H A;  2PCG A;  2EL1 A;  3HH1 A;  2ZVC A;  2DV7 A;  3KEM A;  3UV7 A;  3KEL A;  2HUV A;  2E8S A;  2EGS A;  2E15 A;  2NPN A;  3NEI A;  3LMM A;  2DXX A;  2OWF A;  2PCK A;  3ZGN A;  2DXW A;  1WNG A;  2EN5 A;  2ED3 A;  1VE2 A;  2E8R A;  3KE9 A;  2EH2 A;  2EL0 A;  4EB3 A;  2PB4 A;  2EJZ A;  1VHV A;  2E4R A;  2DXV A;  2YBQ A;  5HW4 A;  4H4D A;  2E17 A;  3KWP A;  2PCM A;  2DEK A;  1CBF A;  2P6D A;  2P6I A;  4MUY A;  2PCH A;  1PJT A;  2DV3 A;  3UWM A;  1VCE A;  2PB5 A;  4N7B A;  2CBF A;  2P6K A;  2OWU A;  3UTD A;  2E4N A;  2EK7 A;  3NUT A;  2DSH A;  2HR8 A;  2EL2 A;  1WDE A;  2P5C A;  3SZU A;  1WYZ A;  2EK2 A;  3T0F A;  1V9A A;  2OWG A;  1VA0 A;  3UV3 A;  4MV0 A;  2Z6R A;  2P6L A;  2EJJ A;  4H4C A;  2PCI A;  2HUX A;  2OWK A;  2EMU A;  2ELE A;  2ED5 A;  2EK3 A;  2ZVB A;  2E16 A;  2EL3 A;  2E8Q A;  2HUQ A;  2EMR A;  2EHL A;  2BB3 A;  2DSI A;  2ENI A;  2HUT A;  2P2X A;  2QBU A;  1PJS A;  3TIX B;  2YBO A;  2OWV A;  3KEF A;  2EKA A;  2E0K A;  2P5F A;  3NDC A;  2PB6 A;  3URK A;  3KE8 A;  3DNF A;  3UV6 A;  2E7R A;  3ZGL A;  4H4E A;  3F7T A;  2PCA A;  1PJQ A;  3ND1 A;  4MUX A;  2EH5 A;  2KYY A;  2EGL A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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