2DSIA

Crystal structure of glu171 to arg mutant of diphthine synthase
Total Genus 81
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
81
sequence length
265
structure length
265
Chain Sequence
MVLYFIGLGLYDERDITVKGLEIAKKCDYVFAEFYTSLMAGTTLGRIQKLIGKEIRVLSREDVELNFENIVLPLAKENDVAFLTPGDPLVATTHAELRIRAKRAGVESYVIHAPSIYSAVGITGLHIYKFGKSATVAYPEGNWFPTSYYDVIKENAERGLHTLLFLDIKARKRMYMTANEAMELLLKVEDMKKGGVFTDDTLVVVLARAGSLNPTIRAGYVKDLIREDFGDPPHILIVPGKLHIVEAEYLVEIAGAPREILRVNV
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of diphthine synthase from Pyrococcus horikoshii OT3
rcsb
source organism Pyrococcus horikoshii
molecule tags Transferase
molecule keywords diphthine synthase
total genus 81
structure length 265
sequence length 265
chains with identical sequence B
ec nomenclature ec 2.1.1.98: Diphthine synthase.
pdb deposition date 2006-06-30

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00590 TP_methylase Tetrapyrrole (Corrin/Porphyrin) Methylases
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.950.10 Alpha Beta 2-Layer Sandwich Methyltransferase, Cobalt-precorrin-4 Transmethylase; Domain 2 Methyltransferase, Cobalt-precorrin-4 Transmethylase; Domain 2 2dsiA02
3.40.1010.10 Alpha Beta 3-Layer(aba) Sandwich Cobalt-precorrin-4 Transmethylase; domain 1 Cobalt-precorrin-4 Transmethylase; Domain 1 2dsiA01
2P6DA 2OWKA 2DSIA 3NEIA 2EKAA 2HR8A 2EK3A 1VCEA 2PCAA 1V9AA 2HUTA 2YBOA 2DXWA 3I4TA 3KWPA 2EN5A 2EHLA 2ELDA 2EL0A 2E8QA 2P5CA 2E7RA 1S4DA 2EJJA 2HUQA 2Z6RA 2DV5A 1CBFA 2EMUA 2E15A 2OWVA 3FQ6A 2EK4A 5HW4A 2EL1A 2EJZA 2DV4A 2PB5A 1PJSA 2P2XA 2NPNA 2YBQA 1VE2A 2ED3A 2HUXA 2OWFA 2ZVBA 3HH1A 2PB6A 2OWGA 2E0KA 1WYZA 2EGSA 3ND1A 2E08A 2E4RA 2PCGA 2BB3A 2OWUA 1VHVA 2E8RA 2EHCA 2EL3A 1WDEA 2P6LA 2EMRA 2P9DA 2DEKA 2E8SA 2PCHA 2DV3A 2E0NA 2PCKA 2EH2A 2PCIA 2EEQA 2EK7A 2E07A 1PJQA 2E4NA 2PCMA 2ED5A 2EGBA 2CBFA 2EH4A 2ENIA 2E16A 2E17A 1WNGA 2EH5A 1VA0A 2ZVCA 4E16A 2EJKA 2P6IA 2DXXA 2ELEA 3NUTA 2E8HA 2EL2A 2QBUA 2DSGA 2P6KA 2EGLA 2EK2A 2P5FA 2PB4A 3NDCA 3FFYA 2DXVA 1PJTA 2DSHA 2DV7A 2HUVA
chains in the Genus database with same CATH superfamily
3F7TA 2P6DA 2OWKA 2DSIA 3NEIA 3TIXB 3UV6A 2KYYA 2EKAA 2HR8A 2EK3A 1VCEA 2PCAA 1V9AA 3KE8A 2HUTA 2YBOA 2DXWA 3I4TA 3KWPA 2EN5A 2EHLA 2ELDA 2EL0A 2E8QA 2P5CA 2E7RA 1S4DA 2EJJA 2HUQA 4H4DA 2Z6RA 2DV5A 1CBFA 4MV5A 2EMUA 2E15A 2OWVA 3FQ6A 2EK4A 5HW4A 2EL1A 2EJZA 2DV4A 3UTDA 2PB5A 3UWMA 1PJSA 2P2XA 4H4EA 2NPNA 2YBQA 1VE2A 2ED3A 4MV0A 3T0GA 2HUXA 2OWFA 2ZVBA 3HH1A 2PB6A 4MUXA 2OWGA 2E0KA 1WYZA 3SZOA 3KE9A 2EGSA 3ND1A 2E08A 2E4RA 2PCGA 3T0FA 2BB3A 2OWUA 3SZUA 3KELA 1VHVA 3KEFA 2E8RA 2EHCA 2EL3A 1WDEA 2P6LA 2EMRA 4MUYA 2P9DA 2DEKA 2E8SA 2PCHA 2DV3A 2E0NA 2PCKA 3UV7A 2EH2A 2PCIA 2EEQA 2EK7A 3SZLA 2E07A 3UTCA 1PJQA 2E4NA 2PCMA 2ED5A 2EGBA 2CBFA 2EH4A 3LMMA 2ENIA 2E16A 2E17A 1WNGA 2EH5A 1VA0A 2ZVCA 3KEMA 4E16A 4N7BA 2EJKA 2P6IA 3ZGNA 2DXXA 2ELEA 3NUTA 2E8HA 2EL2A 2QBUA 2DSGA 2P6KA 2EGLA 2EK2A 3UV3A 2P5FA 2PB4A 3NDCA 3DNFA 3FFYA 3ZGLA 2DXVA 1PJTA 2DSHA 2DV7A 4H4CA 3URKA 4EB3A 2HUVA
chains in the Genus database with same CATH topology
3F7TA 2P6DA 2OWKA 2DSIA 3NEIA 3TIXB 3UV6A 2KYYA 2EKAA 2HR8A 2EK3A 1VCEA 2PCAA 1V9AA 3KE8A 2HUTA 2YBOA 2DXWA 3I4TA 3KWPA 2EN5A 2EHLA 2ELDA 2EL0A 2E8QA 2P5CA 2E7RA 1S4DA 2EJJA 2HUQA 4H4DA 2Z6RA 2DV5A 1CBFA 4MV5A 2EMUA 2E15A 2OWVA 3FQ6A 2EK4A 5HW4A 2EL1A 2EJZA 2DV4A 3UTDA 2PB5A 3UWMA 1PJSA 2P2XA 4H4EA 2NPNA 2YBQA 1VE2A 2ED3A 4MV0A 3T0GA 2HUXA 2OWFA 2ZVBA 3HH1A 2PB6A 4MUXA 2OWGA 2E0KA 1WYZA 3SZOA 3KE9A 2EGSA 3ND1A 2E08A 2E4RA 2PCGA 3T0FA 2BB3A 2OWUA 3SZUA 3KELA 1VHVA 3KEFA 2E8RA 2EHCA 2EL3A 1WDEA 2P6LA 2EMRA 4MUYA 2P9DA 2DEKA 2E8SA 2PCHA 2DV3A 2E0NA 2PCKA 3UV7A 2EH2A 2PCIA 2EEQA 2EK7A 3SZLA 2E07A 3UTCA 1PJQA 2E4NA 2PCMA 2ED5A 2EGBA 2CBFA 2EH4A 3LMMA 2ENIA 2E16A 2E17A 1WNGA 2EH5A 1VA0A 2ZVCA 3KEMA 4E16A 4N7BA 2EJKA 2P6IA 3ZGNA 2DXXA 2ELEA 3NUTA 2E8HA 2EL2A 2QBUA 2DSGA 2P6KA 2EGLA 2EK2A 3UV3A 2P5FA 2PB4A 3NDCA 3DNFA 3FFYA 3ZGLA 2DXVA 1PJTA 2DSHA 2DV7A 4H4CA 3URKA 4EB3A 2HUVA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2P6D A;  2OWK A;  2DSI A;  3NEI A;  2EKA A;  2HR8 A;  2EK3 A;  1VCE A;  2PCA A;  1V9A A;  2HUT A;  2YBO A;  2DXW A;  3I4T A;  3KWP A;  2EN5 A;  2EHL A;  2ELD A;  2EL0 A;  2E8Q A;  2P5C A;  2E7R A;  1S4D A;  2EJJ A;  2HUQ A;  2Z6R A;  2DV5 A;  1CBF A;  2EMU A;  2E15 A;  2OWV A;  3FQ6 A;  2EK4 A;  5HW4 A;  2EL1 A;  2EJZ A;  2DV4 A;  2PB5 A;  1PJS A;  2P2X A;  2NPN A;  2YBQ A;  1VE2 A;  2ED3 A;  2HUX A;  2OWF A;  2ZVB A;  3HH1 A;  2PB6 A;  2OWG A;  2E0K A;  1WYZ A;  2EGS A;  3ND1 A;  2E08 A;  2E4R A;  2PCG A;  2BB3 A;  2OWU A;  1VHV A;  2E8R A;  2EHC A;  2EL3 A;  1WDE A;  2P6L A;  2EMR A;  2P9D A;  2DEK A;  2E8S A;  2PCH A;  2DV3 A;  2E0N A;  2PCK A;  2EH2 A;  2PCI A;  2EEQ A;  2EK7 A;  2E07 A;  1PJQ A;  2E4N A;  2PCM A;  2ED5 A;  2EGB A;  2CBF A;  2EH4 A;  2ENI A;  2E16 A;  2E17 A;  1WNG A;  2EH5 A;  1VA0 A;  2ZVC A;  4E16 A;  2EJK A;  2P6I A;  2DXX A;  2ELE A;  3NUT A;  2E8H A;  2EL2 A;  2QBU A;  2DSG A;  2P6K A;  2EGL A;  2EK2 A;  2P5F A;  2PB4 A;  3NDC A;  3FFY A;  2DXV A;  1PJT A;  2DSH A;  2DV7 A;  2HUV A; 
#chains in the Genus database with same CATH topology
 3F7T A;  2P6D A;  2OWK A;  2DSI A;  3NEI A;  3TIX B;  3UV6 A;  2KYY A;  2EKA A;  2HR8 A;  2EK3 A;  1VCE A;  2PCA A;  1V9A A;  3KE8 A;  2HUT A;  2YBO A;  2DXW A;  3I4T A;  3KWP A;  2EN5 A;  2EHL A;  2ELD A;  2EL0 A;  2E8Q A;  2P5C A;  2E7R A;  1S4D A;  2EJJ A;  2HUQ A;  4H4D A;  2Z6R A;  2DV5 A;  1CBF A;  4MV5 A;  2EMU A;  2E15 A;  2OWV A;  3FQ6 A;  2EK4 A;  5HW4 A;  2EL1 A;  2EJZ A;  2DV4 A;  3UTD A;  2PB5 A;  3UWM A;  1PJS A;  2P2X A;  4H4E A;  2NPN A;  2YBQ A;  1VE2 A;  2ED3 A;  4MV0 A;  3T0G A;  2HUX A;  2OWF A;  2ZVB A;  3HH1 A;  2PB6 A;  4MUX A;  2OWG A;  2E0K A;  1WYZ A;  3SZO A;  3KE9 A;  2EGS A;  3ND1 A;  2E08 A;  2E4R A;  2PCG A;  3T0F A;  2BB3 A;  2OWU A;  3SZU A;  3KEL A;  1VHV A;  3KEF A;  2E8R A;  2EHC A;  2EL3 A;  1WDE A;  2P6L A;  2EMR A;  4MUY A;  2P9D A;  2DEK A;  2E8S A;  2PCH A;  2DV3 A;  2E0N A;  2PCK A;  3UV7 A;  2EH2 A;  2PCI A;  2EEQ A;  2EK7 A;  3SZL A;  2E07 A;  3UTC A;  1PJQ A;  2E4N A;  2PCM A;  2ED5 A;  2EGB A;  2CBF A;  2EH4 A;  3LMM A;  2ENI A;  2E16 A;  2E17 A;  1WNG A;  2EH5 A;  1VA0 A;  2ZVC A;  3KEM A;  4E16 A;  4N7B A;  2EJK A;  2P6I A;  3ZGN A;  2DXX A;  2ELE A;  3NUT A;  2E8H A;  2EL2 A;  2QBU A;  2DSG A;  2P6K A;  2EGL A;  2EK2 A;  3UV3 A;  2P5F A;  2PB4 A;  3NDC A;  3DNF A;  3FFY A;  3ZGL A;  2DXV A;  1PJT A;  2DSH A;  2DV7 A;  4H4C A;  3URK A;  4EB3 A;  2HUV A; 
#chains in the Genus database with same CATH homology
 3F7T A;  2P6D A;  2OWK A;  2DSI A;  3NEI A;  3TIX B;  3UV6 A;  2KYY A;  2EKA A;  2HR8 A;  2EK3 A;  1VCE A;  2PCA A;  1V9A A;  3KE8 A;  2HUT A;  2YBO A;  2DXW A;  3I4T A;  3KWP A;  2EN5 A;  2EHL A;  2ELD A;  2EL0 A;  2E8Q A;  2P5C A;  2E7R A;  1S4D A;  2EJJ A;  2HUQ A;  4H4D A;  2Z6R A;  2DV5 A;  1CBF A;  4MV5 A;  2EMU A;  2E15 A;  2OWV A;  3FQ6 A;  2EK4 A;  5HW4 A;  2EL1 A;  2EJZ A;  2DV4 A;  3UTD A;  2PB5 A;  3UWM A;  1PJS A;  2P2X A;  4H4E A;  2NPN A;  2YBQ A;  1VE2 A;  2ED3 A;  4MV0 A;  3T0G A;  2HUX A;  2OWF A;  2ZVB A;  3HH1 A;  2PB6 A;  4MUX A;  2OWG A;  2E0K A;  1WYZ A;  3SZO A;  3KE9 A;  2EGS A;  3ND1 A;  2E08 A;  2E4R A;  2PCG A;  3T0F A;  2BB3 A;  2OWU A;  3SZU A;  3KEL A;  1VHV A;  3KEF A;  2E8R A;  2EHC A;  2EL3 A;  1WDE A;  2P6L A;  2EMR A;  4MUY A;  2P9D A;  2DEK A;  2E8S A;  2PCH A;  2DV3 A;  2E0N A;  2PCK A;  3UV7 A;  2EH2 A;  2PCI A;  2EEQ A;  2EK7 A;  3SZL A;  2E07 A;  3UTC A;  1PJQ A;  2E4N A;  2PCM A;  2ED5 A;  2EGB A;  2CBF A;  2EH4 A;  3LMM A;  2ENI A;  2E16 A;  2E17 A;  1WNG A;  2EH5 A;  1VA0 A;  2ZVC A;  3KEM A;  4E16 A;  4N7B A;  2EJK A;  2P6I A;  3ZGN A;  2DXX A;  2ELE A;  3NUT A;  2E8H A;  2EL2 A;  2QBU A;  2DSG A;  2P6K A;  2EGL A;  2EK2 A;  3UV3 A;  2P5F A;  2PB4 A;  3NDC A;  3DNF A;  3FFY A;  3ZGL A;  2DXV A;  1PJT A;  2DSH A;  2DV7 A;  4H4C A;  3URK A;  4EB3 A;  2HUV A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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