2DV3A

Crystal structure of leu65 to arg mutant of diphthine synthase
Total Genus 81
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
81
sequence length
265
structure length
265
Chain Sequence
MVLYFIGLGLYDERDITVKGLEIAKKCDYVFAEFYTSLMAGTTLGRIQKLIGKEIRVLSREDVERNFENIVLPLAKENDVAFLTPGDPLVATTHAELRIRAKRAGVESYVIHAPSIYSAVGITGLHIYKFGKSATVAYPEGNWFPTSYYDVIKENAERGLHTLLFLDIKAEKRMYMTANEAMELLLKVEDMKKGGVFTDDTLVVVLARAGSLNPTIRAGYVKDLIREDFGDPPHILIVPGKLHIVEAEYLVEIAGAPREILRVNV
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title Crystal structure of diphthine synthase from Pyrococcus horikoshii OT3
rcsb
source organism Pyrococcus horikoshii
molecule tags Transferase
molecule keywords diphthine synthase
total genus 81
structure length 265
sequence length 265
chains with identical sequence B
ec nomenclature ec 2.1.1.98: Diphthine synthase.
pdb deposition date 2006-07-28

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00590 TP_methylase Tetrapyrrole (Corrin/Porphyrin) Methylases
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.950.10 Alpha Beta 2-Layer Sandwich Methyltransferase, Cobalt-precorrin-4 Transmethylase; Domain 2 Methyltransferase, Cobalt-precorrin-4 Transmethylase; Domain 2 2dv3A02
3.40.1010.10 Alpha Beta 3-Layer(aba) Sandwich Cobalt-precorrin-4 Transmethylase; domain 1 Cobalt-precorrin-4 Transmethylase; Domain 1 2dv3A01
2P5CA 2YBOA 2E07A 2YBQA 2EK7A 2EHCA 2OWGA 2DSIA 2DXVA 2ELEA 2EH5A 2PCIA 2EK3A 3FFYA 2P6LA 1VHVA 2P6KA 2E8RA 2DV5A 2E15A 2EH2A 2EN5A 3NEIA 2EJZA 2DV7A 2NPNA 2EL0A 2OWFA 2OWVA 2HUXA 5HW4A 3I4TA 1S4DA 2DSHA 2P6IA 2EMUA 2P9DA 2EGSA 2E16A 2PCHA 3NDCA 2BB3A 2Z6RA 2EHLA 2CBFA 2EEQA 2EK2A 2DXXA 2EJJA 2DV3A 2ELDA 2E7RA 2ZVBA 1VA0A 1WNGA 1CBFA 2E8QA 2PCGA 2QBUA 3HH1A 1V9AA 2ENIA 2PB6A 3NUTA 2E0NA 2DEKA 2E8HA 2EJKA 2DSGA 3FQ6A 2P2XA 1PJSA 2PCKA 2ZVCA 2PB4A 2P6DA 2DXWA 2DV4A 1PJTA 1VE2A 1VCEA 2EK4A 2OWKA 2EL2A 2E17A 2E4NA 2EL3A 2HUVA 2OWUA 2E4RA 2P5FA 2PCMA 3ND1A 2EL1A 1WDEA 2EH4A 2PB5A 3KWPA 1WYZA 2ED5A 2HUTA 2HR8A 2EKAA 2E0KA 2E08A 2E8SA 2PCAA 2ED3A 1PJQA 2EMRA 2HUQA 2EGBA 4E16A 2EGLA
chains in the Genus database with same CATH superfamily
2P5CA 2YBOA 2E07A 2YBQA 2EK7A 3ZGLA 2EHCA 2OWGA 2DSIA 2DXVA 2ELEA 3UV3A 2EH5A 4N7BA 4MUYA 2PCIA 2EK3A 3FFYA 2P6LA 1VHVA 2P6KA 2E8RA 2DV5A 2E15A 2EH2A 2EN5A 4MUXA 3NEIA 2EJZA 2DV7A 2NPNA 2EL0A 2OWFA 2OWVA 2HUXA 5HW4A 3I4TA 1S4DA 3ZGNA 2DSHA 2P6IA 2EMUA 2P9DA 2EGSA 2E16A 3UTCA 2PCHA 3NDCA 2BB3A 2Z6RA 2EHLA 2CBFA 2EEQA 2EK2A 2DXXA 2EJJA 2DV3A 2ELDA 2E7RA 2ZVBA 1VA0A 1WNGA 1CBFA 3UV6A 2E8QA 2PCGA 2QBUA 3HH1A 4H4CA 2KYYA 1V9AA 2ENIA 2PB6A 3NUTA 2E0NA 2DEKA 2E8HA 2EJKA 2DSGA 3FQ6A 3KEMA 3KE9A 2P2XA 1PJSA 2PCKA 2ZVCA 2PB4A 3UV7A 2P6DA 2DXWA 2DV4A 1PJTA 1VE2A 1VCEA 2EK4A 3SZLA 3DNFA 3F7TA 2OWKA 2EL2A 2E17A 3UTDA 2E4NA 2EL3A 3URKA 2HUVA 2OWUA 3SZUA 2E4RA 2P5FA 4MV5A 4H4EA 2PCMA 3ND1A 3KELA 3KEFA 2EL1A 4H4DA 4MV0A 1WDEA 4EB3A 2EH4A 2PB5A 3KWPA 3SZOA 1WYZA 2ED5A 3TIXB 3T0FA 2HUTA 2HR8A 2EKAA 3T0GA 2E0KA 3KE8A 2E08A 2E8SA 2PCAA 2ED3A 1PJQA 2EMRA 2HUQA 2EGBA 4E16A 3LMMA 3UWMA 2EGLA
chains in the Genus database with same CATH topology
2P5CA 2YBOA 2E07A 2YBQA 2EK7A 3ZGLA 2EHCA 2OWGA 2DSIA 2DXVA 2ELEA 3UV3A 2EH5A 4N7BA 4MUYA 2PCIA 2EK3A 3FFYA 2P6LA 1VHVA 2P6KA 2E8RA 2DV5A 2E15A 2EH2A 2EN5A 4MUXA 3NEIA 2EJZA 2DV7A 2NPNA 2EL0A 2OWFA 2OWVA 2HUXA 5HW4A 3I4TA 1S4DA 3ZGNA 2DSHA 2P6IA 2EMUA 2P9DA 2EGSA 2E16A 3UTCA 2PCHA 3NDCA 2BB3A 2Z6RA 2EHLA 2CBFA 2EEQA 2EK2A 2DXXA 2EJJA 2DV3A 2ELDA 2E7RA 2ZVBA 1VA0A 1WNGA 1CBFA 3UV6A 2E8QA 2PCGA 2QBUA 3HH1A 4H4CA 2KYYA 1V9AA 2ENIA 2PB6A 3NUTA 2E0NA 2DEKA 2E8HA 2EJKA 2DSGA 3FQ6A 3KEMA 3KE9A 2P2XA 1PJSA 2PCKA 2ZVCA 2PB4A 3UV7A 2P6DA 2DXWA 2DV4A 1PJTA 1VE2A 1VCEA 2EK4A 3SZLA 3DNFA 3F7TA 2OWKA 2EL2A 2E17A 3UTDA 2E4NA 2EL3A 3URKA 2HUVA 2OWUA 3SZUA 2E4RA 2P5FA 4MV5A 4H4EA 2PCMA 3ND1A 3KELA 3KEFA 2EL1A 4H4DA 4MV0A 1WDEA 4EB3A 2EH4A 2PB5A 3KWPA 3SZOA 1WYZA 2ED5A 3TIXB 3T0FA 2HUTA 2HR8A 2EKAA 3T0GA 2E0KA 3KE8A 2E08A 2E8SA 2PCAA 2ED3A 1PJQA 2EMRA 2HUQA 2EGBA 4E16A 3LMMA 3UWMA 2EGLA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2P5C A;  2YBO A;  2E07 A;  2YBQ A;  2EK7 A;  2EHC A;  2OWG A;  2DSI A;  2DXV A;  2ELE A;  2EH5 A;  2PCI A;  2EK3 A;  3FFY A;  2P6L A;  1VHV A;  2P6K A;  2E8R A;  2DV5 A;  2E15 A;  2EH2 A;  2EN5 A;  3NEI A;  2EJZ A;  2DV7 A;  2NPN A;  2EL0 A;  2OWF A;  2OWV A;  2HUX A;  5HW4 A;  3I4T A;  1S4D A;  2DSH A;  2P6I A;  2EMU A;  2P9D A;  2EGS A;  2E16 A;  2PCH A;  3NDC A;  2BB3 A;  2Z6R A;  2EHL A;  2CBF A;  2EEQ A;  2EK2 A;  2DXX A;  2EJJ A;  2DV3 A;  2ELD A;  2E7R A;  2ZVB A;  1VA0 A;  1WNG A;  1CBF A;  2E8Q A;  2PCG A;  2QBU A;  3HH1 A;  1V9A A;  2ENI A;  2PB6 A;  3NUT A;  2E0N A;  2DEK A;  2E8H A;  2EJK A;  2DSG A;  3FQ6 A;  2P2X A;  1PJS A;  2PCK A;  2ZVC A;  2PB4 A;  2P6D A;  2DXW A;  2DV4 A;  1PJT A;  1VE2 A;  1VCE A;  2EK4 A;  2OWK A;  2EL2 A;  2E17 A;  2E4N A;  2EL3 A;  2HUV A;  2OWU A;  2E4R A;  2P5F A;  2PCM A;  3ND1 A;  2EL1 A;  1WDE A;  2EH4 A;  2PB5 A;  3KWP A;  1WYZ A;  2ED5 A;  2HUT A;  2HR8 A;  2EKA A;  2E0K A;  2E08 A;  2E8S A;  2PCA A;  2ED3 A;  1PJQ A;  2EMR A;  2HUQ A;  2EGB A;  4E16 A;  2EGL A; 
#chains in the Genus database with same CATH topology
 2P5C A;  2YBO A;  2E07 A;  2YBQ A;  2EK7 A;  3ZGL A;  2EHC A;  2OWG A;  2DSI A;  2DXV A;  2ELE A;  3UV3 A;  2EH5 A;  4N7B A;  4MUY A;  2PCI A;  2EK3 A;  3FFY A;  2P6L A;  1VHV A;  2P6K A;  2E8R A;  2DV5 A;  2E15 A;  2EH2 A;  2EN5 A;  4MUX A;  3NEI A;  2EJZ A;  2DV7 A;  2NPN A;  2EL0 A;  2OWF A;  2OWV A;  2HUX A;  5HW4 A;  3I4T A;  1S4D A;  3ZGN A;  2DSH A;  2P6I A;  2EMU A;  2P9D A;  2EGS A;  2E16 A;  3UTC A;  2PCH A;  3NDC A;  2BB3 A;  2Z6R A;  2EHL A;  2CBF A;  2EEQ A;  2EK2 A;  2DXX A;  2EJJ A;  2DV3 A;  2ELD A;  2E7R A;  2ZVB A;  1VA0 A;  1WNG A;  1CBF A;  3UV6 A;  2E8Q A;  2PCG A;  2QBU A;  3HH1 A;  4H4C A;  2KYY A;  1V9A A;  2ENI A;  2PB6 A;  3NUT A;  2E0N A;  2DEK A;  2E8H A;  2EJK A;  2DSG A;  3FQ6 A;  3KEM A;  3KE9 A;  2P2X A;  1PJS A;  2PCK A;  2ZVC A;  2PB4 A;  3UV7 A;  2P6D A;  2DXW A;  2DV4 A;  1PJT A;  1VE2 A;  1VCE A;  2EK4 A;  3SZL A;  3DNF A;  3F7T A;  2OWK A;  2EL2 A;  2E17 A;  3UTD A;  2E4N A;  2EL3 A;  3URK A;  2HUV A;  2OWU A;  3SZU A;  2E4R A;  2P5F A;  4MV5 A;  4H4E A;  2PCM A;  3ND1 A;  3KEL A;  3KEF A;  2EL1 A;  4H4D A;  4MV0 A;  1WDE A;  4EB3 A;  2EH4 A;  2PB5 A;  3KWP A;  3SZO A;  1WYZ A;  2ED5 A;  3TIX B;  3T0F A;  2HUT A;  2HR8 A;  2EKA A;  3T0G A;  2E0K A;  3KE8 A;  2E08 A;  2E8S A;  2PCA A;  2ED3 A;  1PJQ A;  2EMR A;  2HUQ A;  2EGB A;  4E16 A;  3LMM A;  3UWM A;  2EGL A; 
#chains in the Genus database with same CATH homology
 2P5C A;  2YBO A;  2E07 A;  2YBQ A;  2EK7 A;  3ZGL A;  2EHC A;  2OWG A;  2DSI A;  2DXV A;  2ELE A;  3UV3 A;  2EH5 A;  4N7B A;  4MUY A;  2PCI A;  2EK3 A;  3FFY A;  2P6L A;  1VHV A;  2P6K A;  2E8R A;  2DV5 A;  2E15 A;  2EH2 A;  2EN5 A;  4MUX A;  3NEI A;  2EJZ A;  2DV7 A;  2NPN A;  2EL0 A;  2OWF A;  2OWV A;  2HUX A;  5HW4 A;  3I4T A;  1S4D A;  3ZGN A;  2DSH A;  2P6I A;  2EMU A;  2P9D A;  2EGS A;  2E16 A;  3UTC A;  2PCH A;  3NDC A;  2BB3 A;  2Z6R A;  2EHL A;  2CBF A;  2EEQ A;  2EK2 A;  2DXX A;  2EJJ A;  2DV3 A;  2ELD A;  2E7R A;  2ZVB A;  1VA0 A;  1WNG A;  1CBF A;  3UV6 A;  2E8Q A;  2PCG A;  2QBU A;  3HH1 A;  4H4C A;  2KYY A;  1V9A A;  2ENI A;  2PB6 A;  3NUT A;  2E0N A;  2DEK A;  2E8H A;  2EJK A;  2DSG A;  3FQ6 A;  3KEM A;  3KE9 A;  2P2X A;  1PJS A;  2PCK A;  2ZVC A;  2PB4 A;  3UV7 A;  2P6D A;  2DXW A;  2DV4 A;  1PJT A;  1VE2 A;  1VCE A;  2EK4 A;  3SZL A;  3DNF A;  3F7T A;  2OWK A;  2EL2 A;  2E17 A;  3UTD A;  2E4N A;  2EL3 A;  3URK A;  2HUV A;  2OWU A;  3SZU A;  2E4R A;  2P5F A;  4MV5 A;  4H4E A;  2PCM A;  3ND1 A;  3KEL A;  3KEF A;  2EL1 A;  4H4D A;  4MV0 A;  1WDE A;  4EB3 A;  2EH4 A;  2PB5 A;  3KWP A;  3SZO A;  1WYZ A;  2ED5 A;  3TIX B;  3T0F A;  2HUT A;  2HR8 A;  2EKA A;  3T0G A;  2E0K A;  3KE8 A;  2E08 A;  2E8S A;  2PCA A;  2ED3 A;  1PJQ A;  2EMR A;  2HUQ A;  2EGB A;  4E16 A;  3LMM A;  3UWM A;  2EGL A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...