2DV3A

Crystal structure of leu65 to arg mutant of diphthine synthase
Total Genus 81
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
81
sequence length
265
structure length
265
Chain Sequence
b'MVLYFIGLGLYDERDITVKGLEIAKKCDYVFAEFYTSLMAGTTLGRIQKLIGKEIRVLSREDVERNFENIVLPLAKENDVAFLTPGDPLVATTHAELRIRAKRAGVESYVIHAPSIYSAVGITGLHIYKFGKSATVAYPEGNWFPTSYYDVIKENAERGLHTLLFLDIKAEKRMYMTANEAMELLLKVEDMKKGGVFTDDTLVVVLARAGSLNPTIRAGYVKDLIREDFGDPPHILIVPGKLHIVEAEYLVEIAGAPREILRVNV'
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
molecule keywords diphthine synthase
publication title Crystal structure of diphthine synthase from Pyrococcus horikoshii OT3
rcsb
source organism Pyrococcus horikoshii
molecule tags Transferase
total genus 81
structure length 265
sequence length 265
chains with identical sequence B
ec nomenclature ec 2.1.1.98: Diphthine synthase.
pdb deposition date 2006-07-28

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00590 TP_methylase Tetrapyrrole (Corrin/Porphyrin) Methylases
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.950.10 Alpha Beta 2-Layer Sandwich Methyltransferase, Cobalt-precorrin-4 Transmethylase; Domain 2 Methyltransferase, Cobalt-precorrin-4 Transmethylase; Domain 2 2dv3A02
3.40.1010.10 Alpha Beta 3-Layer(aba) Sandwich Cobalt-precorrin-4 Transmethylase; domain 1 Cobalt-precorrin-4 Transmethylase; Domain 1 2dv3A01
1VA0A 2P9DA 2EGLA 2HUXA 2DV4A 2P6DA 2DEKA 2E0NA 2P5CA 2E0KA 2EMUA 2EJZA 2HUVA 2ZVCA 3KWPA 2PB4A 2EK2A 1VCEA 2EJKA 2DV3A 3NEIA 2P6LA 2PCMA 2E8RA 3NDCA 2E8QA 2EMRA 2ZVBA 2OWVA 2PCKA 3ND1A 2ENIA 2EH2A 2E08A 2PB6A 2EK3A 2E07A 2ELEA 2OWGA 2DSIA 2P5FA 2PCIA 2OWFA 2EK4A 2CBFA 2DSHA 2EL1A 5HW4A 2E7RA 2P6KA 2EL0A 2EEQA 2EGSA 2HUQA 2HR8A 1PJTA 2EKAA 2YBOA 2ED3A 2EHCA 2PCAA 1VE2A 3FQ6A 2Z6RA 2DXXA 3FFYA 2DSGA 2DXWA 2EH4A 2DV7A 2EH5A 2BB3A 1PJQA 1WDEA 2E17A 2DXVA 2PCGA 2YBQA 2EL2A 4E16A 2E8SA 1WYZA 2E15A 2QBUA 1VHVA 2EHLA 1WNGA 2OWKA 2P6IA 2NPNA 3I4TA 2E8HA 2ED5A 3HH1A 2PB5A 2EN5A 1V9AA 2E16A 1S4DA 2EL3A 2ELDA 2E4NA 3NUTA 2PCHA 2EGBA 2HUTA 2EJJA 2P2XA 2DV5A 2EK7A 1PJSA 2E4RA 2OWUA 1CBFA
chains in the Genus database with same CATH superfamily
1VA0A 2P9DA 2EGLA 4MUXA 2HUXA 2DV4A 2KYYA 3UWMA 3UV7A 2P6DA 3SZOA 2DEKA 2E0NA 2P5CA 2E0KA 2EMUA 2EJZA 2HUVA 2ZVCA 3KWPA 2PB4A 2EK2A 4H4CA 4MV5A 1VCEA 2EJKA 3KE9A 2DV3A 3NEIA 2P6LA 2PCMA 3T0FA 3KEFA 4MV0A 2E8RA 3NDCA 3SZUA 3ZGNA 2E8QA 2EMRA 2ZVBA 4MUYA 2OWVA 2PCKA 3ND1A 2ENIA 4N7BA 2EH2A 2E08A 2PB6A 2EK3A 3ZGLA 2E07A 2ELEA 2OWGA 2DSIA 2P5FA 2PCIA 2OWFA 2EK4A 2CBFA 2DSHA 2EL1A 5HW4A 3UV6A 3DNFA 2E7RA 2P6KA 2EL0A 3KEMA 3LMMA 2EEQA 2EGSA 4H4EA 2HUQA 2HR8A 1PJTA 2EKAA 2YBOA 2ED3A 2EHCA 2PCAA 1VE2A 3FQ6A 2Z6RA 3UTDA 2DXXA 3FFYA 2DSGA 4H4DA 2DXWA 2EH4A 3F7TA 2DV7A 2EH5A 2BB3A 1PJQA 1WDEA 2E17A 2DXVA 2PCGA 3TIXB 2YBQA 2EL2A 4E16A 2E8SA 1WYZA 2E15A 3UTCA 3URKA 4EB3A 2QBUA 1VHVA 2EHLA 1WNGA 3T0GA 2OWKA 3UV3A 2P6IA 2NPNA 3I4TA 2E8HA 2ED5A 3HH1A 2PB5A 2EN5A 1V9AA 2E16A 3SZLA 1S4DA 2EL3A 3KELA 3KE8A 2ELDA 2E4NA 3NUTA 2PCHA 2EGBA 2HUTA 2EJJA 2P2XA 2DV5A 2EK7A 1PJSA 2E4RA 2OWUA 1CBFA
chains in the Genus database with same CATH topology
1VA0A 2P9DA 2EGLA 4MUXA 2HUXA 2DV4A 2KYYA 3UWMA 3UV7A 2P6DA 3SZOA 2DEKA 2E0NA 2P5CA 2E0KA 2EMUA 2EJZA 2HUVA 2ZVCA 3KWPA 2PB4A 2EK2A 4H4CA 4MV5A 1VCEA 2EJKA 3KE9A 2DV3A 3NEIA 2P6LA 2PCMA 3T0FA 3KEFA 4MV0A 2E8RA 3NDCA 3SZUA 3ZGNA 2E8QA 2EMRA 2ZVBA 4MUYA 2OWVA 2PCKA 3ND1A 2ENIA 4N7BA 2EH2A 2E08A 2PB6A 2EK3A 3ZGLA 2E07A 2ELEA 2OWGA 2DSIA 2P5FA 2PCIA 2OWFA 2EK4A 2CBFA 2DSHA 2EL1A 5HW4A 3UV6A 3DNFA 2E7RA 2P6KA 2EL0A 3KEMA 3LMMA 2EEQA 2EGSA 4H4EA 2HUQA 2HR8A 1PJTA 2EKAA 2YBOA 2ED3A 2EHCA 2PCAA 1VE2A 3FQ6A 2Z6RA 3UTDA 2DXXA 3FFYA 2DSGA 4H4DA 2DXWA 2EH4A 3F7TA 2DV7A 2EH5A 2BB3A 1PJQA 1WDEA 2E17A 2DXVA 2PCGA 3TIXB 2YBQA 2EL2A 4E16A 2E8SA 1WYZA 2E15A 3UTCA 3URKA 4EB3A 2QBUA 1VHVA 2EHLA 1WNGA 3T0GA 2OWKA 3UV3A 2P6IA 2NPNA 3I4TA 2E8HA 2ED5A 3HH1A 2PB5A 2EN5A 1V9AA 2E16A 3SZLA 1S4DA 2EL3A 3KELA 3KE8A 2ELDA 2E4NA 3NUTA 2PCHA 2EGBA 2HUTA 2EJJA 2P2XA 2DV5A 2EK7A 1PJSA 2E4RA 2OWUA 1CBFA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1VA0 A;  2P9D A;  2EGL A;  2HUX A;  2DV4 A;  2P6D A;  2DEK A;  2E0N A;  2P5C A;  2E0K A;  2EMU A;  2EJZ A;  2HUV A;  2ZVC A;  3KWP A;  2PB4 A;  2EK2 A;  1VCE A;  2EJK A;  2DV3 A;  3NEI A;  2P6L A;  2PCM A;  2E8R A;  3NDC A;  2E8Q A;  2EMR A;  2ZVB A;  2OWV A;  2PCK A;  3ND1 A;  2ENI A;  2EH2 A;  2E08 A;  2PB6 A;  2EK3 A;  2E07 A;  2ELE A;  2OWG A;  2DSI A;  2P5F A;  2PCI A;  2OWF A;  2EK4 A;  2CBF A;  2DSH A;  2EL1 A;  5HW4 A;  2E7R A;  2P6K A;  2EL0 A;  2EEQ A;  2EGS A;  2HUQ A;  2HR8 A;  1PJT A;  2EKA A;  2YBO A;  2ED3 A;  2EHC A;  2PCA A;  1VE2 A;  3FQ6 A;  2Z6R A;  2DXX A;  3FFY A;  2DSG A;  2DXW A;  2EH4 A;  2DV7 A;  2EH5 A;  2BB3 A;  1PJQ A;  1WDE A;  2E17 A;  2DXV A;  2PCG A;  2YBQ A;  2EL2 A;  4E16 A;  2E8S A;  1WYZ A;  2E15 A;  2QBU A;  1VHV A;  2EHL A;  1WNG A;  2OWK A;  2P6I A;  2NPN A;  3I4T A;  2E8H A;  2ED5 A;  3HH1 A;  2PB5 A;  2EN5 A;  1V9A A;  2E16 A;  1S4D A;  2EL3 A;  2ELD A;  2E4N A;  3NUT A;  2PCH A;  2EGB A;  2HUT A;  2EJJ A;  2P2X A;  2DV5 A;  2EK7 A;  1PJS A;  2E4R A;  2OWU A;  1CBF A; 
#chains in the Genus database with same CATH topology
 1VA0 A;  2P9D A;  2EGL A;  4MUX A;  2HUX A;  2DV4 A;  2KYY A;  3UWM A;  3UV7 A;  2P6D A;  3SZO A;  2DEK A;  2E0N A;  2P5C A;  2E0K A;  2EMU A;  2EJZ A;  2HUV A;  2ZVC A;  3KWP A;  2PB4 A;  2EK2 A;  4H4C A;  4MV5 A;  1VCE A;  2EJK A;  3KE9 A;  2DV3 A;  3NEI A;  2P6L A;  2PCM A;  3T0F A;  3KEF A;  4MV0 A;  2E8R A;  3NDC A;  3SZU A;  3ZGN A;  2E8Q A;  2EMR A;  2ZVB A;  4MUY A;  2OWV A;  2PCK A;  3ND1 A;  2ENI A;  4N7B A;  2EH2 A;  2E08 A;  2PB6 A;  2EK3 A;  3ZGL A;  2E07 A;  2ELE A;  2OWG A;  2DSI A;  2P5F A;  2PCI A;  2OWF A;  2EK4 A;  2CBF A;  2DSH A;  2EL1 A;  5HW4 A;  3UV6 A;  3DNF A;  2E7R A;  2P6K A;  2EL0 A;  3KEM A;  3LMM A;  2EEQ A;  2EGS A;  4H4E A;  2HUQ A;  2HR8 A;  1PJT A;  2EKA A;  2YBO A;  2ED3 A;  2EHC A;  2PCA A;  1VE2 A;  3FQ6 A;  2Z6R A;  3UTD A;  2DXX A;  3FFY A;  2DSG A;  4H4D A;  2DXW A;  2EH4 A;  3F7T A;  2DV7 A;  2EH5 A;  2BB3 A;  1PJQ A;  1WDE A;  2E17 A;  2DXV A;  2PCG A;  3TIX B;  2YBQ A;  2EL2 A;  4E16 A;  2E8S A;  1WYZ A;  2E15 A;  3UTC A;  3URK A;  4EB3 A;  2QBU A;  1VHV A;  2EHL A;  1WNG A;  3T0G A;  2OWK A;  3UV3 A;  2P6I A;  2NPN A;  3I4T A;  2E8H A;  2ED5 A;  3HH1 A;  2PB5 A;  2EN5 A;  1V9A A;  2E16 A;  3SZL A;  1S4D A;  2EL3 A;  3KEL A;  3KE8 A;  2ELD A;  2E4N A;  3NUT A;  2PCH A;  2EGB A;  2HUT A;  2EJJ A;  2P2X A;  2DV5 A;  2EK7 A;  1PJS A;  2E4R A;  2OWU A;  1CBF A; 
#chains in the Genus database with same CATH homology
 1VA0 A;  2P9D A;  2EGL A;  4MUX A;  2HUX A;  2DV4 A;  2KYY A;  3UWM A;  3UV7 A;  2P6D A;  3SZO A;  2DEK A;  2E0N A;  2P5C A;  2E0K A;  2EMU A;  2EJZ A;  2HUV A;  2ZVC A;  3KWP A;  2PB4 A;  2EK2 A;  4H4C A;  4MV5 A;  1VCE A;  2EJK A;  3KE9 A;  2DV3 A;  3NEI A;  2P6L A;  2PCM A;  3T0F A;  3KEF A;  4MV0 A;  2E8R A;  3NDC A;  3SZU A;  3ZGN A;  2E8Q A;  2EMR A;  2ZVB A;  4MUY A;  2OWV A;  2PCK A;  3ND1 A;  2ENI A;  4N7B A;  2EH2 A;  2E08 A;  2PB6 A;  2EK3 A;  3ZGL A;  2E07 A;  2ELE A;  2OWG A;  2DSI A;  2P5F A;  2PCI A;  2OWF A;  2EK4 A;  2CBF A;  2DSH A;  2EL1 A;  5HW4 A;  3UV6 A;  3DNF A;  2E7R A;  2P6K A;  2EL0 A;  3KEM A;  3LMM A;  2EEQ A;  2EGS A;  4H4E A;  2HUQ A;  2HR8 A;  1PJT A;  2EKA A;  2YBO A;  2ED3 A;  2EHC A;  2PCA A;  1VE2 A;  3FQ6 A;  2Z6R A;  3UTD A;  2DXX A;  3FFY A;  2DSG A;  4H4D A;  2DXW A;  2EH4 A;  3F7T A;  2DV7 A;  2EH5 A;  2BB3 A;  1PJQ A;  1WDE A;  2E17 A;  2DXV A;  2PCG A;  3TIX B;  2YBQ A;  2EL2 A;  4E16 A;  2E8S A;  1WYZ A;  2E15 A;  3UTC A;  3URK A;  4EB3 A;  2QBU A;  1VHV A;  2EHL A;  1WNG A;  3T0G A;  2OWK A;  3UV3 A;  2P6I A;  2NPN A;  3I4T A;  2E8H A;  2ED5 A;  3HH1 A;  2PB5 A;  2EN5 A;  1V9A A;  2E16 A;  3SZL A;  1S4D A;  2EL3 A;  3KEL A;  3KE8 A;  2ELD A;  2E4N A;  3NUT A;  2PCH A;  2EGB A;  2HUT A;  2EJJ A;  2P2X A;  2DV5 A;  2EK7 A;  1PJS A;  2E4R A;  2OWU A;  1CBF A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...