2DV3A

Crystal structure of leu65 to arg mutant of diphthine synthase
Total Genus 81
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
81
sequence length
265
structure length
265
Chain Sequence
MVLYFIGLGLYDERDITVKGLEIAKKCDYVFAEFYTSLMAGTTLGRIQKLIGKEIRVLSREDVERNFENIVLPLAKENDVAFLTPGDPLVATTHAELRIRAKRAGVESYVIHAPSIYSAVGITGLHIYKFGKSATVAYPEGNWFPTSYYDVIKENAERGLHTLLFLDIKAEKRMYMTANEAMELLLKVEDMKKGGVFTDDTLVVVLARAGSLNPTIRAGYVKDLIREDFGDPPHILIVPGKLHIVEAEYLVEIAGAPREILRVNV
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of diphthine synthase from Pyrococcus horikoshii OT3
rcsb
source organism Pyrococcus horikoshii
molecule tags Transferase
molecule keywords diphthine synthase
total genus 81
structure length 265
sequence length 265
chains with identical sequence B
ec nomenclature ec 2.1.1.98: Diphthine synthase.
pdb deposition date 2006-07-28

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00590 TP_methylase Tetrapyrrole (Corrin/Porphyrin) Methylases
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.950.10 Alpha Beta 2-Layer Sandwich Methyltransferase, Cobalt-precorrin-4 Transmethylase; Domain 2 Methyltransferase, Cobalt-precorrin-4 Transmethylase; Domain 2 2dv3A02
3.40.1010.10 Alpha Beta 3-Layer(aba) Sandwich Cobalt-precorrin-4 Transmethylase; domain 1 Cobalt-precorrin-4 Transmethylase; Domain 1 2dv3A01
2EKAA 2HUTA 2P6DA 2NPNA 2EK7A 1PJSA 2BB3A 2P5CA 2ZVCA 2CBFA 2EJKA 2OWGA 2DV7A 1WYZA 2DEKA 2PCMA 2P9DA 2EHLA 2EMRA 1WDEA 2E07A 2ENIA 2PB4A 2EL2A 2E8RA 2P6LA 2E8SA 3ND1A 1WNGA 2EGBA 2ED3A 2EK2A 2DSIA 1VE2A 2E0NA 5HW4A 2YBOA 3NDCA 2DSGA 2EH5A 1PJTA 2ZVBA 2DXXA 2DV3A 2ED5A 1V9AA 2PCKA 2EGSA 2HUXA 2OWVA 2OWFA 2EEQA 2EL0A 2PCGA 2PCAA 1CBFA 2P2XA 2E08A 2ELEA 4E16A 2EHCA 2EH2A 2PCHA 2PCIA 2EGLA 2OWKA 3NEIA 2E8HA 1VA0A 2ELDA 1PJQA 2DXVA 2EK4A 2P5FA 2OWUA 2EK3A 2DV5A 2EL1A 2E15A 3FFYA 1VHVA 1S4DA 2E4NA 3NUTA 2E4RA 2HUQA 2PB6A 2QBUA 2E7RA 3KWPA 2PB5A 2E16A 2HR8A 2E17A 3FQ6A 2Z6RA 2EMUA 2P6KA 2HUVA 2YBQA 2E8QA 2EH4A 3HH1A 2DXWA 2DV4A 2P6IA 1VCEA 2E0KA 3I4TA 2DSHA 2EJZA 2EN5A 2EL3A 2EJJA
chains in the Genus database with same CATH superfamily
2EKAA 3TIXB 2HUTA 2P6DA 2NPNA 2EK7A 3KEMA 3UV6A 1PJSA 2BB3A 2P5CA 2ZVCA 2CBFA 2EJKA 2OWGA 4H4DA 2DV7A 1WYZA 2DEKA 2PCMA 2P9DA 2KYYA 2EHLA 2EMRA 1WDEA 2E07A 4MV5A 3DNFA 2ENIA 2PB4A 3SZUA 2EL2A 2E8RA 2P6LA 2E8SA 3ND1A 1WNGA 2EGBA 2ED3A 3T0GA 2EK2A 2DSIA 1VE2A 2E0NA 4N7BA 5HW4A 2YBOA 3KELA 3LMMA 3NDCA 2DSGA 2EH5A 1PJTA 2ZVBA 2DXXA 2DV3A 2ED5A 1V9AA 2PCKA 2EGSA 2HUXA 3KE9A 2OWVA 2OWFA 2EEQA 2EL0A 2PCGA 3KE8A 2PCAA 1CBFA 3URKA 2P2XA 2E08A 2ELEA 4E16A 2EHCA 4H4EA 4H4CA 3UV3A 2EH2A 2PCHA 2PCIA 3UWMA 3ZGNA 2EGLA 2OWKA 3NEIA 2E8HA 1VA0A 2ELDA 1PJQA 2DXVA 2EK4A 2P5FA 2OWUA 2EK3A 3F7TA 2DV5A 4MUYA 2EL1A 2E15A 3FFYA 4MV0A 1VHVA 1S4DA 3T0FA 2E4NA 3NUTA 2E4RA 4MUXA 3SZOA 2HUQA 2PB6A 2QBUA 2E7RA 3KWPA 2PB5A 2E16A 2HR8A 2E17A 3FQ6A 3KEFA 2Z6RA 2EMUA 2P6KA 2HUVA 2YBQA 3SZLA 2E8QA 2EH4A 3HH1A 3UV7A 2DXWA 2DV4A 2P6IA 3ZGLA 1VCEA 2E0KA 3UTCA 3UTDA 3I4TA 2DSHA 2EJZA 2EN5A 4EB3A 2EL3A 2EJJA
chains in the Genus database with same CATH topology
2EKAA 3TIXB 2HUTA 2P6DA 2NPNA 2EK7A 3KEMA 3UV6A 1PJSA 2BB3A 2P5CA 2ZVCA 2CBFA 2EJKA 2OWGA 4H4DA 2DV7A 1WYZA 2DEKA 2PCMA 2P9DA 2KYYA 2EHLA 2EMRA 1WDEA 2E07A 4MV5A 3DNFA 2ENIA 2PB4A 3SZUA 2EL2A 2E8RA 2P6LA 2E8SA 3ND1A 1WNGA 2EGBA 2ED3A 3T0GA 2EK2A 2DSIA 1VE2A 2E0NA 4N7BA 5HW4A 2YBOA 3KELA 3LMMA 3NDCA 2DSGA 2EH5A 1PJTA 2ZVBA 2DXXA 2DV3A 2ED5A 1V9AA 2PCKA 2EGSA 2HUXA 3KE9A 2OWVA 2OWFA 2EEQA 2EL0A 2PCGA 3KE8A 2PCAA 1CBFA 3URKA 2P2XA 2E08A 2ELEA 4E16A 2EHCA 4H4EA 4H4CA 3UV3A 2EH2A 2PCHA 2PCIA 3UWMA 3ZGNA 2EGLA 2OWKA 3NEIA 2E8HA 1VA0A 2ELDA 1PJQA 2DXVA 2EK4A 2P5FA 2OWUA 2EK3A 3F7TA 2DV5A 4MUYA 2EL1A 2E15A 3FFYA 4MV0A 1VHVA 1S4DA 3T0FA 2E4NA 3NUTA 2E4RA 4MUXA 3SZOA 2HUQA 2PB6A 2QBUA 2E7RA 3KWPA 2PB5A 2E16A 2HR8A 2E17A 3FQ6A 3KEFA 2Z6RA 2EMUA 2P6KA 2HUVA 2YBQA 3SZLA 2E8QA 2EH4A 3HH1A 3UV7A 2DXWA 2DV4A 2P6IA 3ZGLA 1VCEA 2E0KA 3UTCA 3UTDA 3I4TA 2DSHA 2EJZA 2EN5A 4EB3A 2EL3A 2EJJA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2EKA A;  2HUT A;  2P6D A;  2NPN A;  2EK7 A;  1PJS A;  2BB3 A;  2P5C A;  2ZVC A;  2CBF A;  2EJK A;  2OWG A;  2DV7 A;  1WYZ A;  2DEK A;  2PCM A;  2P9D A;  2EHL A;  2EMR A;  1WDE A;  2E07 A;  2ENI A;  2PB4 A;  2EL2 A;  2E8R A;  2P6L A;  2E8S A;  3ND1 A;  1WNG A;  2EGB A;  2ED3 A;  2EK2 A;  2DSI A;  1VE2 A;  2E0N A;  5HW4 A;  2YBO A;  3NDC A;  2DSG A;  2EH5 A;  1PJT A;  2ZVB A;  2DXX A;  2DV3 A;  2ED5 A;  1V9A A;  2PCK A;  2EGS A;  2HUX A;  2OWV A;  2OWF A;  2EEQ A;  2EL0 A;  2PCG A;  2PCA A;  1CBF A;  2P2X A;  2E08 A;  2ELE A;  4E16 A;  2EHC A;  2EH2 A;  2PCH A;  2PCI A;  2EGL A;  2OWK A;  3NEI A;  2E8H A;  1VA0 A;  2ELD A;  1PJQ A;  2DXV A;  2EK4 A;  2P5F A;  2OWU A;  2EK3 A;  2DV5 A;  2EL1 A;  2E15 A;  3FFY A;  1VHV A;  1S4D A;  2E4N A;  3NUT A;  2E4R A;  2HUQ A;  2PB6 A;  2QBU A;  2E7R A;  3KWP A;  2PB5 A;  2E16 A;  2HR8 A;  2E17 A;  3FQ6 A;  2Z6R A;  2EMU A;  2P6K A;  2HUV A;  2YBQ A;  2E8Q A;  2EH4 A;  3HH1 A;  2DXW A;  2DV4 A;  2P6I A;  1VCE A;  2E0K A;  3I4T A;  2DSH A;  2EJZ A;  2EN5 A;  2EL3 A;  2EJJ A; 
#chains in the Genus database with same CATH topology
 2EKA A;  3TIX B;  2HUT A;  2P6D A;  2NPN A;  2EK7 A;  3KEM A;  3UV6 A;  1PJS A;  2BB3 A;  2P5C A;  2ZVC A;  2CBF A;  2EJK A;  2OWG A;  4H4D A;  2DV7 A;  1WYZ A;  2DEK A;  2PCM A;  2P9D A;  2KYY A;  2EHL A;  2EMR A;  1WDE A;  2E07 A;  4MV5 A;  3DNF A;  2ENI A;  2PB4 A;  3SZU A;  2EL2 A;  2E8R A;  2P6L A;  2E8S A;  3ND1 A;  1WNG A;  2EGB A;  2ED3 A;  3T0G A;  2EK2 A;  2DSI A;  1VE2 A;  2E0N A;  4N7B A;  5HW4 A;  2YBO A;  3KEL A;  3LMM A;  3NDC A;  2DSG A;  2EH5 A;  1PJT A;  2ZVB A;  2DXX A;  2DV3 A;  2ED5 A;  1V9A A;  2PCK A;  2EGS A;  2HUX A;  3KE9 A;  2OWV A;  2OWF A;  2EEQ A;  2EL0 A;  2PCG A;  3KE8 A;  2PCA A;  1CBF A;  3URK A;  2P2X A;  2E08 A;  2ELE A;  4E16 A;  2EHC A;  4H4E A;  4H4C A;  3UV3 A;  2EH2 A;  2PCH A;  2PCI A;  3UWM A;  3ZGN A;  2EGL A;  2OWK A;  3NEI A;  2E8H A;  1VA0 A;  2ELD A;  1PJQ A;  2DXV A;  2EK4 A;  2P5F A;  2OWU A;  2EK3 A;  3F7T A;  2DV5 A;  4MUY A;  2EL1 A;  2E15 A;  3FFY A;  4MV0 A;  1VHV A;  1S4D A;  3T0F A;  2E4N A;  3NUT A;  2E4R A;  4MUX A;  3SZO A;  2HUQ A;  2PB6 A;  2QBU A;  2E7R A;  3KWP A;  2PB5 A;  2E16 A;  2HR8 A;  2E17 A;  3FQ6 A;  3KEF A;  2Z6R A;  2EMU A;  2P6K A;  2HUV A;  2YBQ A;  3SZL A;  2E8Q A;  2EH4 A;  3HH1 A;  3UV7 A;  2DXW A;  2DV4 A;  2P6I A;  3ZGL A;  1VCE A;  2E0K A;  3UTC A;  3UTD A;  3I4T A;  2DSH A;  2EJZ A;  2EN5 A;  4EB3 A;  2EL3 A;  2EJJ A; 
#chains in the Genus database with same CATH homology
 2EKA A;  3TIX B;  2HUT A;  2P6D A;  2NPN A;  2EK7 A;  3KEM A;  3UV6 A;  1PJS A;  2BB3 A;  2P5C A;  2ZVC A;  2CBF A;  2EJK A;  2OWG A;  4H4D A;  2DV7 A;  1WYZ A;  2DEK A;  2PCM A;  2P9D A;  2KYY A;  2EHL A;  2EMR A;  1WDE A;  2E07 A;  4MV5 A;  3DNF A;  2ENI A;  2PB4 A;  3SZU A;  2EL2 A;  2E8R A;  2P6L A;  2E8S A;  3ND1 A;  1WNG A;  2EGB A;  2ED3 A;  3T0G A;  2EK2 A;  2DSI A;  1VE2 A;  2E0N A;  4N7B A;  5HW4 A;  2YBO A;  3KEL A;  3LMM A;  3NDC A;  2DSG A;  2EH5 A;  1PJT A;  2ZVB A;  2DXX A;  2DV3 A;  2ED5 A;  1V9A A;  2PCK A;  2EGS A;  2HUX A;  3KE9 A;  2OWV A;  2OWF A;  2EEQ A;  2EL0 A;  2PCG A;  3KE8 A;  2PCA A;  1CBF A;  3URK A;  2P2X A;  2E08 A;  2ELE A;  4E16 A;  2EHC A;  4H4E A;  4H4C A;  3UV3 A;  2EH2 A;  2PCH A;  2PCI A;  3UWM A;  3ZGN A;  2EGL A;  2OWK A;  3NEI A;  2E8H A;  1VA0 A;  2ELD A;  1PJQ A;  2DXV A;  2EK4 A;  2P5F A;  2OWU A;  2EK3 A;  3F7T A;  2DV5 A;  4MUY A;  2EL1 A;  2E15 A;  3FFY A;  4MV0 A;  1VHV A;  1S4D A;  3T0F A;  2E4N A;  3NUT A;  2E4R A;  4MUX A;  3SZO A;  2HUQ A;  2PB6 A;  2QBU A;  2E7R A;  3KWP A;  2PB5 A;  2E16 A;  2HR8 A;  2E17 A;  3FQ6 A;  3KEF A;  2Z6R A;  2EMU A;  2P6K A;  2HUV A;  2YBQ A;  3SZL A;  2E8Q A;  2EH4 A;  3HH1 A;  3UV7 A;  2DXW A;  2DV4 A;  2P6I A;  3ZGL A;  1VCE A;  2E0K A;  3UTC A;  3UTD A;  3I4T A;  2DSH A;  2EJZ A;  2EN5 A;  4EB3 A;  2EL3 A;  2EJJ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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