2DV5A

Crystal structure of leu65 to ala mutant of diphthine synthase
Total Genus 81
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
81
sequence length
265
structure length
265
Chain Sequence
MVLYFIGLGLYDERDITVKGLEIAKKCDYVFAEFYTSLMAGTTLGRIQKLIGKEIRVLSREDVEANFENIVLPLAKENDVAFLTPGDPLVATTHAELRIRAKRAGVESYVIHAPSIYSAVGITGLHIYKFGKSATVAYPEGNWFPTSYYDVIKENAERGLHTLLFLDIKAEKRMYMTANEAMELLLKVEDMKKGGVFTDDTLVVVLARAGSLNPTIRAGYVKDLIREDFGDPPHILIVPGKLHIVEAEYLVEIAGAPREILRVNV
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of diphthine synthase from Pyrococcus horikoshii OT3
rcsb
source organism Pyrococcus horikoshii
molecule tags Transferase
molecule keywords diphthine synthase
total genus 81
structure length 265
sequence length 265
chains with identical sequence B
ec nomenclature ec 2.1.1.98: Diphthine synthase.
pdb deposition date 2006-07-28

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00590 TP_methylase Tetrapyrrole (Corrin/Porphyrin) Methylases
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.950.10 Alpha Beta 2-Layer Sandwich Methyltransferase, Cobalt-precorrin-4 Transmethylase; Domain 2 Methyltransferase, Cobalt-precorrin-4 Transmethylase; Domain 2 2dv5A02
3.40.1010.10 Alpha Beta 3-Layer(aba) Sandwich Cobalt-precorrin-4 Transmethylase; domain 1 Cobalt-precorrin-4 Transmethylase; Domain 1 2dv5A01
2PCAA 2E8RA 2ED5A 2OWKA 3NUTA 2EJJA 2DEKA 2EK2A 1PJSA 2EJZA 3ND1A 2DV3A 2EEQA 2EGLA 3NEIA 2EMUA 2EGBA 2HR8A 2EL2A 1PJTA 2EH2A 2DV5A 2OWGA 2DSIA 2E4RA 2ZVCA 1WYZA 2OWFA 2ELDA 2DSHA 1VA0A 2YBOA 2HUVA 2PB5A 1VE2A 1V9AA 2EHLA 2E15A 1WDEA 2OWUA 2EL0A 1PJQA 2P6LA 2EK7A 2ED3A 2P6KA 2E4NA 2E7RA 2EKAA 2QBUA 2EH4A 2E0KA 2HUXA 2P6IA 2P9DA 2E8QA 2CBFA 2EHCA 2EL3A 2PCHA 2HUQA 3FQ6A 2P5CA 4E16A 2EK3A 2DXVA 2P2XA 2PB4A 2BB3A 2EH5A 2E8HA 3KWPA 1VCEA 2PCIA 2OWVA 2PCMA 2PCGA 2DXXA 2EJKA 2PB6A 2ENIA 2EGSA 2ZVBA 2E0NA 2E8SA 2E08A 3HH1A 2P5FA 1VHVA 2PCKA 2EL1A 3FFYA 3NDCA 2E16A 2DV7A 2ELEA 2EK4A 2EMRA 2DV4A 2Z6RA 2YBQA 2E07A 2NPNA 2DXWA 2EN5A 2HUTA 1CBFA 1WNGA 2E17A 2P6DA 2DSGA 1S4DA 5HW4A 3I4TA
chains in the Genus database with same CATH superfamily
2PCAA 2E8RA 2ED5A 2OWKA 3NUTA 2EJJA 4H4CA 2DEKA 2EK2A 4MV0A 1PJSA 2EJZA 3KEMA 3ND1A 2DV3A 3KEFA 2EEQA 2EGLA 3NEIA 2EMUA 2EGBA 2HR8A 2EL2A 1PJTA 2EH2A 2DV5A 2OWGA 3UTDA 4N7BA 2DSIA 2E4RA 2ZVCA 1WYZA 2OWFA 2ELDA 2DSHA 1VA0A 2YBOA 2HUVA 2PB5A 1VE2A 1V9AA 2EHLA 2E15A 1WDEA 2OWUA 4MUXA 2EL0A 3T0GA 1PJQA 2P6LA 2EK7A 2ED3A 2P6KA 2E4NA 3DNFA 3ZGLA 2E7RA 2EKAA 3KE8A 3UV6A 2QBUA 2EH4A 2E0KA 3UWMA 2HUXA 2P6IA 2P9DA 2E8QA 2CBFA 2EHCA 2EL3A 3SZUA 2PCHA 2HUQA 3FQ6A 2P5CA 3F7TA 4E16A 2EK3A 2DXVA 2P2XA 3SZLA 2PB4A 2BB3A 2EH5A 2E8HA 3KWPA 3UTCA 3SZOA 4EB3A 1VCEA 2PCIA 4MUYA 2OWVA 2PCMA 2PCGA 2DXXA 2EJKA 2PB6A 2ENIA 2EGSA 2ZVBA 2E0NA 2E8SA 2E08A 3HH1A 2P5FA 1VHVA 3LMMA 4H4EA 3T0FA 2PCKA 2KYYA 2EL1A 3UV3A 3KE9A 3FFYA 3ZGNA 3NDCA 2E16A 2DV7A 2ELEA 2EK4A 2EMRA 2DV4A 2Z6RA 4MV5A 2YBQA 2E07A 3UV7A 2NPNA 2DXWA 3TIXB 2EN5A 4H4DA 2HUTA 1CBFA 1WNGA 2E17A 2P6DA 2DSGA 1S4DA 5HW4A 3URKA 3KELA 3I4TA
chains in the Genus database with same CATH topology
2PCAA 2E8RA 2ED5A 2OWKA 3NUTA 2EJJA 4H4CA 2DEKA 2EK2A 4MV0A 1PJSA 2EJZA 3KEMA 3ND1A 2DV3A 3KEFA 2EEQA 2EGLA 3NEIA 2EMUA 2EGBA 2HR8A 2EL2A 1PJTA 2EH2A 2DV5A 2OWGA 3UTDA 4N7BA 2DSIA 2E4RA 2ZVCA 1WYZA 2OWFA 2ELDA 2DSHA 1VA0A 2YBOA 2HUVA 2PB5A 1VE2A 1V9AA 2EHLA 2E15A 1WDEA 2OWUA 4MUXA 2EL0A 3T0GA 1PJQA 2P6LA 2EK7A 2ED3A 2P6KA 2E4NA 3DNFA 3ZGLA 2E7RA 2EKAA 3KE8A 3UV6A 2QBUA 2EH4A 2E0KA 3UWMA 2HUXA 2P6IA 2P9DA 2E8QA 2CBFA 2EHCA 2EL3A 3SZUA 2PCHA 2HUQA 3FQ6A 2P5CA 3F7TA 4E16A 2EK3A 2DXVA 2P2XA 3SZLA 2PB4A 2BB3A 2EH5A 2E8HA 3KWPA 3UTCA 3SZOA 4EB3A 1VCEA 2PCIA 4MUYA 2OWVA 2PCMA 2PCGA 2DXXA 2EJKA 2PB6A 2ENIA 2EGSA 2ZVBA 2E0NA 2E8SA 2E08A 3HH1A 2P5FA 1VHVA 3LMMA 4H4EA 3T0FA 2PCKA 2KYYA 2EL1A 3UV3A 3KE9A 3FFYA 3ZGNA 3NDCA 2E16A 2DV7A 2ELEA 2EK4A 2EMRA 2DV4A 2Z6RA 4MV5A 2YBQA 2E07A 3UV7A 2NPNA 2DXWA 3TIXB 2EN5A 4H4DA 2HUTA 1CBFA 1WNGA 2E17A 2P6DA 2DSGA 1S4DA 5HW4A 3URKA 3KELA 3I4TA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2PCA A;  2E8R A;  2ED5 A;  2OWK A;  3NUT A;  2EJJ A;  2DEK A;  2EK2 A;  1PJS A;  2EJZ A;  3ND1 A;  2DV3 A;  2EEQ A;  2EGL A;  3NEI A;  2EMU A;  2EGB A;  2HR8 A;  2EL2 A;  1PJT A;  2EH2 A;  2DV5 A;  2OWG A;  2DSI A;  2E4R A;  2ZVC A;  1WYZ A;  2OWF A;  2ELD A;  2DSH A;  1VA0 A;  2YBO A;  2HUV A;  2PB5 A;  1VE2 A;  1V9A A;  2EHL A;  2E15 A;  1WDE A;  2OWU A;  2EL0 A;  1PJQ A;  2P6L A;  2EK7 A;  2ED3 A;  2P6K A;  2E4N A;  2E7R A;  2EKA A;  2QBU A;  2EH4 A;  2E0K A;  2HUX A;  2P6I A;  2P9D A;  2E8Q A;  2CBF A;  2EHC A;  2EL3 A;  2PCH A;  2HUQ A;  3FQ6 A;  2P5C A;  4E16 A;  2EK3 A;  2DXV A;  2P2X A;  2PB4 A;  2BB3 A;  2EH5 A;  2E8H A;  3KWP A;  1VCE A;  2PCI A;  2OWV A;  2PCM A;  2PCG A;  2DXX A;  2EJK A;  2PB6 A;  2ENI A;  2EGS A;  2ZVB A;  2E0N A;  2E8S A;  2E08 A;  3HH1 A;  2P5F A;  1VHV A;  2PCK A;  2EL1 A;  3FFY A;  3NDC A;  2E16 A;  2DV7 A;  2ELE A;  2EK4 A;  2EMR A;  2DV4 A;  2Z6R A;  2YBQ A;  2E07 A;  2NPN A;  2DXW A;  2EN5 A;  2HUT A;  1CBF A;  1WNG A;  2E17 A;  2P6D A;  2DSG A;  1S4D A;  5HW4 A;  3I4T A; 
#chains in the Genus database with same CATH topology
 2PCA A;  2E8R A;  2ED5 A;  2OWK A;  3NUT A;  2EJJ A;  4H4C A;  2DEK A;  2EK2 A;  4MV0 A;  1PJS A;  2EJZ A;  3KEM A;  3ND1 A;  2DV3 A;  3KEF A;  2EEQ A;  2EGL A;  3NEI A;  2EMU A;  2EGB A;  2HR8 A;  2EL2 A;  1PJT A;  2EH2 A;  2DV5 A;  2OWG A;  3UTD A;  4N7B A;  2DSI A;  2E4R A;  2ZVC A;  1WYZ A;  2OWF A;  2ELD A;  2DSH A;  1VA0 A;  2YBO A;  2HUV A;  2PB5 A;  1VE2 A;  1V9A A;  2EHL A;  2E15 A;  1WDE A;  2OWU A;  4MUX A;  2EL0 A;  3T0G A;  1PJQ A;  2P6L A;  2EK7 A;  2ED3 A;  2P6K A;  2E4N A;  3DNF A;  3ZGL A;  2E7R A;  2EKA A;  3KE8 A;  3UV6 A;  2QBU A;  2EH4 A;  2E0K A;  3UWM A;  2HUX A;  2P6I A;  2P9D A;  2E8Q A;  2CBF A;  2EHC A;  2EL3 A;  3SZU A;  2PCH A;  2HUQ A;  3FQ6 A;  2P5C A;  3F7T A;  4E16 A;  2EK3 A;  2DXV A;  2P2X A;  3SZL A;  2PB4 A;  2BB3 A;  2EH5 A;  2E8H A;  3KWP A;  3UTC A;  3SZO A;  4EB3 A;  1VCE A;  2PCI A;  4MUY A;  2OWV A;  2PCM A;  2PCG A;  2DXX A;  2EJK A;  2PB6 A;  2ENI A;  2EGS A;  2ZVB A;  2E0N A;  2E8S A;  2E08 A;  3HH1 A;  2P5F A;  1VHV A;  3LMM A;  4H4E A;  3T0F A;  2PCK A;  2KYY A;  2EL1 A;  3UV3 A;  3KE9 A;  3FFY A;  3ZGN A;  3NDC A;  2E16 A;  2DV7 A;  2ELE A;  2EK4 A;  2EMR A;  2DV4 A;  2Z6R A;  4MV5 A;  2YBQ A;  2E07 A;  3UV7 A;  2NPN A;  2DXW A;  3TIX B;  2EN5 A;  4H4D A;  2HUT A;  1CBF A;  1WNG A;  2E17 A;  2P6D A;  2DSG A;  1S4D A;  5HW4 A;  3URK A;  3KEL A;  3I4T A; 
#chains in the Genus database with same CATH homology
 2PCA A;  2E8R A;  2ED5 A;  2OWK A;  3NUT A;  2EJJ A;  4H4C A;  2DEK A;  2EK2 A;  4MV0 A;  1PJS A;  2EJZ A;  3KEM A;  3ND1 A;  2DV3 A;  3KEF A;  2EEQ A;  2EGL A;  3NEI A;  2EMU A;  2EGB A;  2HR8 A;  2EL2 A;  1PJT A;  2EH2 A;  2DV5 A;  2OWG A;  3UTD A;  4N7B A;  2DSI A;  2E4R A;  2ZVC A;  1WYZ A;  2OWF A;  2ELD A;  2DSH A;  1VA0 A;  2YBO A;  2HUV A;  2PB5 A;  1VE2 A;  1V9A A;  2EHL A;  2E15 A;  1WDE A;  2OWU A;  4MUX A;  2EL0 A;  3T0G A;  1PJQ A;  2P6L A;  2EK7 A;  2ED3 A;  2P6K A;  2E4N A;  3DNF A;  3ZGL A;  2E7R A;  2EKA A;  3KE8 A;  3UV6 A;  2QBU A;  2EH4 A;  2E0K A;  3UWM A;  2HUX A;  2P6I A;  2P9D A;  2E8Q A;  2CBF A;  2EHC A;  2EL3 A;  3SZU A;  2PCH A;  2HUQ A;  3FQ6 A;  2P5C A;  3F7T A;  4E16 A;  2EK3 A;  2DXV A;  2P2X A;  3SZL A;  2PB4 A;  2BB3 A;  2EH5 A;  2E8H A;  3KWP A;  3UTC A;  3SZO A;  4EB3 A;  1VCE A;  2PCI A;  4MUY A;  2OWV A;  2PCM A;  2PCG A;  2DXX A;  2EJK A;  2PB6 A;  2ENI A;  2EGS A;  2ZVB A;  2E0N A;  2E8S A;  2E08 A;  3HH1 A;  2P5F A;  1VHV A;  3LMM A;  4H4E A;  3T0F A;  2PCK A;  2KYY A;  2EL1 A;  3UV3 A;  3KE9 A;  3FFY A;  3ZGN A;  3NDC A;  2E16 A;  2DV7 A;  2ELE A;  2EK4 A;  2EMR A;  2DV4 A;  2Z6R A;  4MV5 A;  2YBQ A;  2E07 A;  3UV7 A;  2NPN A;  2DXW A;  3TIX B;  2EN5 A;  4H4D A;  2HUT A;  1CBF A;  1WNG A;  2E17 A;  2P6D A;  2DSG A;  1S4D A;  5HW4 A;  3URK A;  3KEL A;  3I4T A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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