2DV5A

Crystal structure of leu65 to ala mutant of diphthine synthase
Total Genus 81
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
81
sequence length
265
structure length
265
Chain Sequence
MVLYFIGLGLYDERDITVKGLEIAKKCDYVFAEFYTSLMAGTTLGRIQKLIGKEIRVLSREDVEANFENIVLPLAKENDVAFLTPGDPLVATTHAELRIRAKRAGVESYVIHAPSIYSAVGITGLHIYKFGKSATVAYPEGNWFPTSYYDVIKENAERGLHTLLFLDIKAEKRMYMTANEAMELLLKVEDMKKGGVFTDDTLVVVLARAGSLNPTIRAGYVKDLIREDFGDPPHILIVPGKLHIVEAEYLVEIAGAPREILRVNV
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of diphthine synthase from Pyrococcus horikoshii OT3
rcsb
source organism Pyrococcus horikoshii
molecule tags Transferase
molecule keywords diphthine synthase
total genus 81
structure length 265
sequence length 265
chains with identical sequence B
ec nomenclature ec 2.1.1.98: Diphthine synthase.
pdb deposition date 2006-07-28

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00590 TP_methylase Tetrapyrrole (Corrin/Porphyrin) Methylases
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.950.10 Alpha Beta 2-Layer Sandwich Methyltransferase, Cobalt-precorrin-4 Transmethylase; Domain 2 Methyltransferase, Cobalt-precorrin-4 Transmethylase; Domain 2 2dv5A02
3.40.1010.10 Alpha Beta 3-Layer(aba) Sandwich Cobalt-precorrin-4 Transmethylase; domain 1 Cobalt-precorrin-4 Transmethylase; Domain 1 2dv5A01
2EGLA 2E15A 1VA0A 2EMRA 2HUXA 2EGSA 2PCMA 2ED3A 2CBFA 2P5CA 2E4RA 2PCGA 2E7RA 2OWGA 3HH1A 2PB5A 1PJSA 1WDEA 2DSIA 2EL3A 2EGBA 2NPNA 2DV3A 2ED5A 2E8HA 2PB4A 2P5FA 2E8QA 2EEQA 2OWFA 2DXXA 2EJKA 3NEIA 2YBOA 1WNGA 2EMUA 2E4NA 2EK3A 2ELDA 5HW4A 2PCAA 2PB6A 2EH5A 2EH2A 2EN5A 2P6KA 1VE2A 2EHCA 2DEKA 2HUQA 2QBUA 2P9DA 2DXVA 2E07A 2EHLA 2ELEA 2ZVBA 2P6IA 1VHVA 1V9AA 2DV7A 3FFYA 1WYZA 2EL2A 2OWKA 2EJZA 2P6DA 2PCHA 2E17A 2BB3A 3FQ6A 2EJJA 2OWVA 2HR8A 2DSGA 2YBQA 2EH4A 2DV5A 2ZVCA 2HUVA 2E0NA 1PJQA 2DXWA 2E8SA 1S4DA 1CBFA 2EK4A 2DSHA 4E16A 3KWPA 2EK2A 2Z6RA 2E8RA 2ENIA 2EKAA 2OWUA 2EK7A 1VCEA 2HUTA 2EL1A 2E08A 2EL0A 2PCKA 2P2XA 3NDCA 2PCIA 3ND1A 2P6LA 2DV4A 2E0KA 3I4TA 1PJTA 2E16A 3NUTA
chains in the Genus database with same CATH superfamily
2EGLA 2E15A 1VA0A 2EMRA 2HUXA 4EB3A 2EGSA 2PCMA 2ED3A 2CBFA 3KE9A 4H4DA 2P5CA 2E4RA 2PCGA 2E7RA 2OWGA 3HH1A 3KEMA 2PB5A 1PJSA 1WDEA 2DSIA 2EL3A 2EGBA 2NPNA 2DV3A 2ED5A 2E8HA 2PB4A 2P5FA 3UV3A 2E8QA 2EEQA 2KYYA 2OWFA 2DXXA 2EJKA 3NEIA 2YBOA 1WNGA 2EMUA 4MV5A 2E4NA 2EK3A 2ELDA 5HW4A 2PCAA 2PB6A 3KE8A 2EH5A 3T0FA 2EH2A 2EN5A 2P6KA 1VE2A 3KELA 2EHCA 2DEKA 3DNFA 4MUXA 2HUQA 2QBUA 2P9DA 2DXVA 3F7TA 2E07A 2EHLA 2ELEA 2ZVBA 3T0GA 2P6IA 1VHVA 1V9AA 2DV7A 3FFYA 1WYZA 3SZUA 2EL2A 3UV7A 2OWKA 2EJZA 2P6DA 3LMMA 2PCHA 4MV0A 2E17A 2BB3A 3UV6A 3UTDA 3FQ6A 2EJJA 2OWVA 4H4EA 3SZLA 2HR8A 2DSGA 2YBQA 2EH4A 2DV5A 4N7BA 2ZVCA 2HUVA 2E0NA 3UWMA 1PJQA 2DXWA 2E8SA 1S4DA 1CBFA 2EK4A 4MUYA 2DSHA 4E16A 3KWPA 2EK2A 2Z6RA 3TIXB 2E8RA 2ENIA 3UTCA 3ZGNA 2EKAA 2OWUA 2EK7A 1VCEA 3ZGLA 2HUTA 3URKA 2EL1A 2E08A 2EL0A 2PCKA 3SZOA 2P2XA 3NDCA 2PCIA 3ND1A 2P6LA 2DV4A 2E0KA 3I4TA 1PJTA 2E16A 3NUTA 3KEFA 4H4CA
chains in the Genus database with same CATH topology
2EGLA 2E15A 1VA0A 2EMRA 2HUXA 4EB3A 2EGSA 2PCMA 2ED3A 2CBFA 3KE9A 4H4DA 2P5CA 2E4RA 2PCGA 2E7RA 2OWGA 3HH1A 3KEMA 2PB5A 1PJSA 1WDEA 2DSIA 2EL3A 2EGBA 2NPNA 2DV3A 2ED5A 2E8HA 2PB4A 2P5FA 3UV3A 2E8QA 2EEQA 2KYYA 2OWFA 2DXXA 2EJKA 3NEIA 2YBOA 1WNGA 2EMUA 4MV5A 2E4NA 2EK3A 2ELDA 5HW4A 2PCAA 2PB6A 3KE8A 2EH5A 3T0FA 2EH2A 2EN5A 2P6KA 1VE2A 3KELA 2EHCA 2DEKA 3DNFA 4MUXA 2HUQA 2QBUA 2P9DA 2DXVA 3F7TA 2E07A 2EHLA 2ELEA 2ZVBA 3T0GA 2P6IA 1VHVA 1V9AA 2DV7A 3FFYA 1WYZA 3SZUA 2EL2A 3UV7A 2OWKA 2EJZA 2P6DA 3LMMA 2PCHA 4MV0A 2E17A 2BB3A 3UV6A 3UTDA 3FQ6A 2EJJA 2OWVA 4H4EA 3SZLA 2HR8A 2DSGA 2YBQA 2EH4A 2DV5A 4N7BA 2ZVCA 2HUVA 2E0NA 3UWMA 1PJQA 2DXWA 2E8SA 1S4DA 1CBFA 2EK4A 4MUYA 2DSHA 4E16A 3KWPA 2EK2A 2Z6RA 3TIXB 2E8RA 2ENIA 3UTCA 3ZGNA 2EKAA 2OWUA 2EK7A 1VCEA 3ZGLA 2HUTA 3URKA 2EL1A 2E08A 2EL0A 2PCKA 3SZOA 2P2XA 3NDCA 2PCIA 3ND1A 2P6LA 2DV4A 2E0KA 3I4TA 1PJTA 2E16A 3NUTA 3KEFA 4H4CA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2EGL A;  2E15 A;  1VA0 A;  2EMR A;  2HUX A;  2EGS A;  2PCM A;  2ED3 A;  2CBF A;  2P5C A;  2E4R A;  2PCG A;  2E7R A;  2OWG A;  3HH1 A;  2PB5 A;  1PJS A;  1WDE A;  2DSI A;  2EL3 A;  2EGB A;  2NPN A;  2DV3 A;  2ED5 A;  2E8H A;  2PB4 A;  2P5F A;  2E8Q A;  2EEQ A;  2OWF A;  2DXX A;  2EJK A;  3NEI A;  2YBO A;  1WNG A;  2EMU A;  2E4N A;  2EK3 A;  2ELD A;  5HW4 A;  2PCA A;  2PB6 A;  2EH5 A;  2EH2 A;  2EN5 A;  2P6K A;  1VE2 A;  2EHC A;  2DEK A;  2HUQ A;  2QBU A;  2P9D A;  2DXV A;  2E07 A;  2EHL A;  2ELE A;  2ZVB A;  2P6I A;  1VHV A;  1V9A A;  2DV7 A;  3FFY A;  1WYZ A;  2EL2 A;  2OWK A;  2EJZ A;  2P6D A;  2PCH A;  2E17 A;  2BB3 A;  3FQ6 A;  2EJJ A;  2OWV A;  2HR8 A;  2DSG A;  2YBQ A;  2EH4 A;  2DV5 A;  2ZVC A;  2HUV A;  2E0N A;  1PJQ A;  2DXW A;  2E8S A;  1S4D A;  1CBF A;  2EK4 A;  2DSH A;  4E16 A;  3KWP A;  2EK2 A;  2Z6R A;  2E8R A;  2ENI A;  2EKA A;  2OWU A;  2EK7 A;  1VCE A;  2HUT A;  2EL1 A;  2E08 A;  2EL0 A;  2PCK A;  2P2X A;  3NDC A;  2PCI A;  3ND1 A;  2P6L A;  2DV4 A;  2E0K A;  3I4T A;  1PJT A;  2E16 A;  3NUT A; 
#chains in the Genus database with same CATH topology
 2EGL A;  2E15 A;  1VA0 A;  2EMR A;  2HUX A;  4EB3 A;  2EGS A;  2PCM A;  2ED3 A;  2CBF A;  3KE9 A;  4H4D A;  2P5C A;  2E4R A;  2PCG A;  2E7R A;  2OWG A;  3HH1 A;  3KEM A;  2PB5 A;  1PJS A;  1WDE A;  2DSI A;  2EL3 A;  2EGB A;  2NPN A;  2DV3 A;  2ED5 A;  2E8H A;  2PB4 A;  2P5F A;  3UV3 A;  2E8Q A;  2EEQ A;  2KYY A;  2OWF A;  2DXX A;  2EJK A;  3NEI A;  2YBO A;  1WNG A;  2EMU A;  4MV5 A;  2E4N A;  2EK3 A;  2ELD A;  5HW4 A;  2PCA A;  2PB6 A;  3KE8 A;  2EH5 A;  3T0F A;  2EH2 A;  2EN5 A;  2P6K A;  1VE2 A;  3KEL A;  2EHC A;  2DEK A;  3DNF A;  4MUX A;  2HUQ A;  2QBU A;  2P9D A;  2DXV A;  3F7T A;  2E07 A;  2EHL A;  2ELE A;  2ZVB A;  3T0G A;  2P6I A;  1VHV A;  1V9A A;  2DV7 A;  3FFY A;  1WYZ A;  3SZU A;  2EL2 A;  3UV7 A;  2OWK A;  2EJZ A;  2P6D A;  3LMM A;  2PCH A;  4MV0 A;  2E17 A;  2BB3 A;  3UV6 A;  3UTD A;  3FQ6 A;  2EJJ A;  2OWV A;  4H4E A;  3SZL A;  2HR8 A;  2DSG A;  2YBQ A;  2EH4 A;  2DV5 A;  4N7B A;  2ZVC A;  2HUV A;  2E0N A;  3UWM A;  1PJQ A;  2DXW A;  2E8S A;  1S4D A;  1CBF A;  2EK4 A;  4MUY A;  2DSH A;  4E16 A;  3KWP A;  2EK2 A;  2Z6R A;  3TIX B;  2E8R A;  2ENI A;  3UTC A;  3ZGN A;  2EKA A;  2OWU A;  2EK7 A;  1VCE A;  3ZGL A;  2HUT A;  3URK A;  2EL1 A;  2E08 A;  2EL0 A;  2PCK A;  3SZO A;  2P2X A;  3NDC A;  2PCI A;  3ND1 A;  2P6L A;  2DV4 A;  2E0K A;  3I4T A;  1PJT A;  2E16 A;  3NUT A;  3KEF A;  4H4C A; 
#chains in the Genus database with same CATH homology
 2EGL A;  2E15 A;  1VA0 A;  2EMR A;  2HUX A;  4EB3 A;  2EGS A;  2PCM A;  2ED3 A;  2CBF A;  3KE9 A;  4H4D A;  2P5C A;  2E4R A;  2PCG A;  2E7R A;  2OWG A;  3HH1 A;  3KEM A;  2PB5 A;  1PJS A;  1WDE A;  2DSI A;  2EL3 A;  2EGB A;  2NPN A;  2DV3 A;  2ED5 A;  2E8H A;  2PB4 A;  2P5F A;  3UV3 A;  2E8Q A;  2EEQ A;  2KYY A;  2OWF A;  2DXX A;  2EJK A;  3NEI A;  2YBO A;  1WNG A;  2EMU A;  4MV5 A;  2E4N A;  2EK3 A;  2ELD A;  5HW4 A;  2PCA A;  2PB6 A;  3KE8 A;  2EH5 A;  3T0F A;  2EH2 A;  2EN5 A;  2P6K A;  1VE2 A;  3KEL A;  2EHC A;  2DEK A;  3DNF A;  4MUX A;  2HUQ A;  2QBU A;  2P9D A;  2DXV A;  3F7T A;  2E07 A;  2EHL A;  2ELE A;  2ZVB A;  3T0G A;  2P6I A;  1VHV A;  1V9A A;  2DV7 A;  3FFY A;  1WYZ A;  3SZU A;  2EL2 A;  3UV7 A;  2OWK A;  2EJZ A;  2P6D A;  3LMM A;  2PCH A;  4MV0 A;  2E17 A;  2BB3 A;  3UV6 A;  3UTD A;  3FQ6 A;  2EJJ A;  2OWV A;  4H4E A;  3SZL A;  2HR8 A;  2DSG A;  2YBQ A;  2EH4 A;  2DV5 A;  4N7B A;  2ZVC A;  2HUV A;  2E0N A;  3UWM A;  1PJQ A;  2DXW A;  2E8S A;  1S4D A;  1CBF A;  2EK4 A;  4MUY A;  2DSH A;  4E16 A;  3KWP A;  2EK2 A;  2Z6R A;  3TIX B;  2E8R A;  2ENI A;  3UTC A;  3ZGN A;  2EKA A;  2OWU A;  2EK7 A;  1VCE A;  3ZGL A;  2HUT A;  3URK A;  2EL1 A;  2E08 A;  2EL0 A;  2PCK A;  3SZO A;  2P2X A;  3NDC A;  2PCI A;  3ND1 A;  2P6L A;  2DV4 A;  2E0K A;  3I4T A;  1PJT A;  2E16 A;  3NUT A;  3KEF A;  4H4C A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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