2DV5A

Crystal structure of leu65 to ala mutant of diphthine synthase
Total Genus 81
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
81
sequence length
265
structure length
265
Chain Sequence
b'MVLYFIGLGLYDERDITVKGLEIAKKCDYVFAEFYTSLMAGTTLGRIQKLIGKEIRVLSREDVEANFENIVLPLAKENDVAFLTPGDPLVATTHAELRIRAKRAGVESYVIHAPSIYSAVGITGLHIYKFGKSATVAYPEGNWFPTSYYDVIKENAERGLHTLLFLDIKAEKRMYMTANEAMELLLKVEDMKKGGVFTDDTLVVVLARAGSLNPTIRAGYVKDLIREDFGDPPHILIVPGKLHIVEAEYLVEIAGAPREILRVNV'
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords diphthine synthase
molecule tags Transferase
source organism Pyrococcus horikoshii
publication title Crystal structure of diphthine synthase from Pyrococcus horikoshii OT3
rcsb
total genus 81
structure length 265
sequence length 265
chains with identical sequence B
ec nomenclature ec 2.1.1.98: Diphthine synthase.
pdb deposition date 2006-07-28

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00590 TP_methylase Tetrapyrrole (Corrin/Porphyrin) Methylases
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.950.10 Alpha Beta 2-Layer Sandwich Methyltransferase, Cobalt-precorrin-4 Transmethylase; Domain 2 Methyltransferase, Cobalt-precorrin-4 Transmethylase; Domain 2 2dv5A02
3.40.1010.10 Alpha Beta 3-Layer(aba) Sandwich Cobalt-precorrin-4 Transmethylase; domain 1 Cobalt-precorrin-4 Transmethylase; Domain 1 2dv5A01
2PB4A 2P5FA 2DV4A 2Z6RA 1WNGA 2DXXA 2P9DA 2E0NA 2ED5A 2EH2A 2EK2A 2EL0A 3NDCA 2EH5A 2BB3A 2DV3A 2P5CA 2OWUA 1VCEA 1PJTA 2P2XA 3NUTA 2OWFA 2DSGA 1V9AA 2E8SA 2HR8A 2YBQA 2EMUA 2EHCA 2EMRA 2E7RA 2DV7A 1VE2A 2E16A 2EH4A 2E8QA 2NPNA 4E16A 2E8HA 2EL3A 2HUTA 1CBFA 2EEQA 2EGSA 2EGLA 2EKAA 3FFYA 2EN5A 2EK4A 1PJSA 2PB6A 2E15A 2PCKA 2E4NA 3I4TA 5HW4A 2DSHA 2P6KA 3NEIA 2PCAA 2EK7A 2E8RA 1VA0A 2ELEA 2P6LA 2EGBA 2PCMA 1VHVA 2PCGA 2E4RA 2HUVA 1WYZA 2DEKA 3FQ6A 2E0KA 2OWKA 2EL2A 2DSIA 2DXWA 1WDEA 2EJKA 2E07A 2P6DA 2YBOA 2EHLA 3KWPA 3HH1A 2EL1A 2HUQA 2P6IA 2EJJA 2PCIA 1PJQA 2ZVCA 2EJZA 2QBUA 2E17A 2OWVA 2ENIA 2ED3A 2DXVA 2DV5A 3ND1A 2CBFA 2HUXA 2ELDA 2PCHA 1S4DA 2ZVBA 2E08A 2PB5A 2EK3A 2OWGA
chains in the Genus database with same CATH superfamily
3UWMA 2PB4A 3UTDA 2P5FA 3TIXB 3T0FA 2DV4A 2Z6RA 1WNGA 2DXXA 2P9DA 4H4CA 2E0NA 2ED5A 2EH2A 2EK2A 2EL0A 3NDCA 2EH5A 2BB3A 2DV3A 2P5CA 2OWUA 1VCEA 1PJTA 4EB3A 2P2XA 3NUTA 3KEFA 2OWFA 2DSGA 1V9AA 2E8SA 2HR8A 2YBQA 2EMUA 2EHCA 2EMRA 3SZUA 3ZGLA 2E7RA 2DV7A 1VE2A 2E16A 2EH4A 2E8QA 4MUYA 2NPNA 4E16A 2E8HA 4MUXA 2EL3A 2HUTA 1CBFA 4N7BA 2EEQA 2EGSA 4H4DA 2EGLA 2EKAA 3FFYA 3DNFA 2EN5A 3URKA 2EK4A 1PJSA 2PB6A 2E15A 2PCKA 2E4NA 3I4TA 5HW4A 2DSHA 2P6KA 3NEIA 4MV0A 2PCAA 4H4EA 2EK7A 3LMMA 2E8RA 1VA0A 3UV6A 2ELEA 2P6LA 3UTCA 2EGBA 2PCMA 1VHVA 2PCGA 2E4RA 2HUVA 1WYZA 2DEKA 3FQ6A 2E0KA 2OWKA 2EL2A 2DSIA 2DXWA 1WDEA 2EJKA 2E07A 2P6DA 2YBOA 2EHLA 3KWPA 3HH1A 2EL1A 2HUQA 3F7TA 2P6IA 2EJJA 3KE8A 2PCIA 1PJQA 2ZVCA 3UV3A 2EJZA 3T0GA 2QBUA 2E17A 2OWVA 2ENIA 2ED3A 3KELA 2DXVA 3SZOA 2DV5A 4MV5A 3KE9A 3KEMA 3UV7A 3ND1A 2CBFA 2HUXA 2ELDA 2PCHA 1S4DA 2ZVBA 3SZLA 2E08A 3ZGNA 2KYYA 2PB5A 2EK3A 2OWGA
chains in the Genus database with same CATH topology
3UWMA 2PB4A 3UTDA 2P5FA 3TIXB 3T0FA 2DV4A 2Z6RA 1WNGA 2DXXA 2P9DA 4H4CA 2E0NA 2ED5A 2EH2A 2EK2A 2EL0A 3NDCA 2EH5A 2BB3A 2DV3A 2P5CA 2OWUA 1VCEA 1PJTA 4EB3A 2P2XA 3NUTA 3KEFA 2OWFA 2DSGA 1V9AA 2E8SA 2HR8A 2YBQA 2EMUA 2EHCA 2EMRA 3SZUA 3ZGLA 2E7RA 2DV7A 1VE2A 2E16A 2EH4A 2E8QA 4MUYA 2NPNA 4E16A 2E8HA 4MUXA 2EL3A 2HUTA 1CBFA 4N7BA 2EEQA 2EGSA 4H4DA 2EGLA 2EKAA 3FFYA 3DNFA 2EN5A 3URKA 2EK4A 1PJSA 2PB6A 2E15A 2PCKA 2E4NA 3I4TA 5HW4A 2DSHA 2P6KA 3NEIA 4MV0A 2PCAA 4H4EA 2EK7A 3LMMA 2E8RA 1VA0A 3UV6A 2ELEA 2P6LA 3UTCA 2EGBA 2PCMA 1VHVA 2PCGA 2E4RA 2HUVA 1WYZA 2DEKA 3FQ6A 2E0KA 2OWKA 2EL2A 2DSIA 2DXWA 1WDEA 2EJKA 2E07A 2P6DA 2YBOA 2EHLA 3KWPA 3HH1A 2EL1A 2HUQA 3F7TA 2P6IA 2EJJA 3KE8A 2PCIA 1PJQA 2ZVCA 3UV3A 2EJZA 3T0GA 2QBUA 2E17A 2OWVA 2ENIA 2ED3A 3KELA 2DXVA 3SZOA 2DV5A 4MV5A 3KE9A 3KEMA 3UV7A 3ND1A 2CBFA 2HUXA 2ELDA 2PCHA 1S4DA 2ZVBA 3SZLA 2E08A 3ZGNA 2KYYA 2PB5A 2EK3A 2OWGA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2PB4 A;  2P5F A;  2DV4 A;  2Z6R A;  1WNG A;  2DXX A;  2P9D A;  2E0N A;  2ED5 A;  2EH2 A;  2EK2 A;  2EL0 A;  3NDC A;  2EH5 A;  2BB3 A;  2DV3 A;  2P5C A;  2OWU A;  1VCE A;  1PJT A;  2P2X A;  3NUT A;  2OWF A;  2DSG A;  1V9A A;  2E8S A;  2HR8 A;  2YBQ A;  2EMU A;  2EHC A;  2EMR A;  2E7R A;  2DV7 A;  1VE2 A;  2E16 A;  2EH4 A;  2E8Q A;  2NPN A;  4E16 A;  2E8H A;  2EL3 A;  2HUT A;  1CBF A;  2EEQ A;  2EGS A;  2EGL A;  2EKA A;  3FFY A;  2EN5 A;  2EK4 A;  1PJS A;  2PB6 A;  2E15 A;  2PCK A;  2E4N A;  3I4T A;  5HW4 A;  2DSH A;  2P6K A;  3NEI A;  2PCA A;  2EK7 A;  2E8R A;  1VA0 A;  2ELE A;  2P6L A;  2EGB A;  2PCM A;  1VHV A;  2PCG A;  2E4R A;  2HUV A;  1WYZ A;  2DEK A;  3FQ6 A;  2E0K A;  2OWK A;  2EL2 A;  2DSI A;  2DXW A;  1WDE A;  2EJK A;  2E07 A;  2P6D A;  2YBO A;  2EHL A;  3KWP A;  3HH1 A;  2EL1 A;  2HUQ A;  2P6I A;  2EJJ A;  2PCI A;  1PJQ A;  2ZVC A;  2EJZ A;  2QBU A;  2E17 A;  2OWV A;  2ENI A;  2ED3 A;  2DXV A;  2DV5 A;  3ND1 A;  2CBF A;  2HUX A;  2ELD A;  2PCH A;  1S4D A;  2ZVB A;  2E08 A;  2PB5 A;  2EK3 A;  2OWG A; 
#chains in the Genus database with same CATH topology
 3UWM A;  2PB4 A;  3UTD A;  2P5F A;  3TIX B;  3T0F A;  2DV4 A;  2Z6R A;  1WNG A;  2DXX A;  2P9D A;  4H4C A;  2E0N A;  2ED5 A;  2EH2 A;  2EK2 A;  2EL0 A;  3NDC A;  2EH5 A;  2BB3 A;  2DV3 A;  2P5C A;  2OWU A;  1VCE A;  1PJT A;  4EB3 A;  2P2X A;  3NUT A;  3KEF A;  2OWF A;  2DSG A;  1V9A A;  2E8S A;  2HR8 A;  2YBQ A;  2EMU A;  2EHC A;  2EMR A;  3SZU A;  3ZGL A;  2E7R A;  2DV7 A;  1VE2 A;  2E16 A;  2EH4 A;  2E8Q A;  4MUY A;  2NPN A;  4E16 A;  2E8H A;  4MUX A;  2EL3 A;  2HUT A;  1CBF A;  4N7B A;  2EEQ A;  2EGS A;  4H4D A;  2EGL A;  2EKA A;  3FFY A;  3DNF A;  2EN5 A;  3URK A;  2EK4 A;  1PJS A;  2PB6 A;  2E15 A;  2PCK A;  2E4N A;  3I4T A;  5HW4 A;  2DSH A;  2P6K A;  3NEI A;  4MV0 A;  2PCA A;  4H4E A;  2EK7 A;  3LMM A;  2E8R A;  1VA0 A;  3UV6 A;  2ELE A;  2P6L A;  3UTC A;  2EGB A;  2PCM A;  1VHV A;  2PCG A;  2E4R A;  2HUV A;  1WYZ A;  2DEK A;  3FQ6 A;  2E0K A;  2OWK A;  2EL2 A;  2DSI A;  2DXW A;  1WDE A;  2EJK A;  2E07 A;  2P6D A;  2YBO A;  2EHL A;  3KWP A;  3HH1 A;  2EL1 A;  2HUQ A;  3F7T A;  2P6I A;  2EJJ A;  3KE8 A;  2PCI A;  1PJQ A;  2ZVC A;  3UV3 A;  2EJZ A;  3T0G A;  2QBU A;  2E17 A;  2OWV A;  2ENI A;  2ED3 A;  3KEL A;  2DXV A;  3SZO A;  2DV5 A;  4MV5 A;  3KE9 A;  3KEM A;  3UV7 A;  3ND1 A;  2CBF A;  2HUX A;  2ELD A;  2PCH A;  1S4D A;  2ZVB A;  3SZL A;  2E08 A;  3ZGN A;  2KYY A;  2PB5 A;  2EK3 A;  2OWG A; 
#chains in the Genus database with same CATH homology
 3UWM A;  2PB4 A;  3UTD A;  2P5F A;  3TIX B;  3T0F A;  2DV4 A;  2Z6R A;  1WNG A;  2DXX A;  2P9D A;  4H4C A;  2E0N A;  2ED5 A;  2EH2 A;  2EK2 A;  2EL0 A;  3NDC A;  2EH5 A;  2BB3 A;  2DV3 A;  2P5C A;  2OWU A;  1VCE A;  1PJT A;  4EB3 A;  2P2X A;  3NUT A;  3KEF A;  2OWF A;  2DSG A;  1V9A A;  2E8S A;  2HR8 A;  2YBQ A;  2EMU A;  2EHC A;  2EMR A;  3SZU A;  3ZGL A;  2E7R A;  2DV7 A;  1VE2 A;  2E16 A;  2EH4 A;  2E8Q A;  4MUY A;  2NPN A;  4E16 A;  2E8H A;  4MUX A;  2EL3 A;  2HUT A;  1CBF A;  4N7B A;  2EEQ A;  2EGS A;  4H4D A;  2EGL A;  2EKA A;  3FFY A;  3DNF A;  2EN5 A;  3URK A;  2EK4 A;  1PJS A;  2PB6 A;  2E15 A;  2PCK A;  2E4N A;  3I4T A;  5HW4 A;  2DSH A;  2P6K A;  3NEI A;  4MV0 A;  2PCA A;  4H4E A;  2EK7 A;  3LMM A;  2E8R A;  1VA0 A;  3UV6 A;  2ELE A;  2P6L A;  3UTC A;  2EGB A;  2PCM A;  1VHV A;  2PCG A;  2E4R A;  2HUV A;  1WYZ A;  2DEK A;  3FQ6 A;  2E0K A;  2OWK A;  2EL2 A;  2DSI A;  2DXW A;  1WDE A;  2EJK A;  2E07 A;  2P6D A;  2YBO A;  2EHL A;  3KWP A;  3HH1 A;  2EL1 A;  2HUQ A;  3F7T A;  2P6I A;  2EJJ A;  3KE8 A;  2PCI A;  1PJQ A;  2ZVC A;  3UV3 A;  2EJZ A;  3T0G A;  2QBU A;  2E17 A;  2OWV A;  2ENI A;  2ED3 A;  3KEL A;  2DXV A;  3SZO A;  2DV5 A;  4MV5 A;  3KE9 A;  3KEM A;  3UV7 A;  3ND1 A;  2CBF A;  2HUX A;  2ELD A;  2PCH A;  1S4D A;  2ZVB A;  3SZL A;  2E08 A;  3ZGN A;  2KYY A;  2PB5 A;  2EK3 A;  2OWG A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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