2DV7A

Crystal structure of lys187 to arg mutant of diphthine synthase
Total Genus 82
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
82
sequence length
265
structure length
265
Chain Sequence
MVLYFIGLGLYDERDITVKGLEIAKKCDYVFAEFYTSLMAGTTLGRIQKLIGKEIRVLSREDVELNFENIVLPLAKENDVAFLTPGDPLVATTHAELRIRAKRAGVESYVIHAPSIYSAVGITGLHIYKFGKSATVAYPEGNWFPTSYYDVIKENAERGLHTLLFLDIKAEKRMYMTANEAMELLLRVEDMKKGGVFTDDTLVVVLARAGSLNPTIRAGYVKDLIREDFGDPPHILIVPGKLHIVEAEYLVEIAGAPREILRVNV
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title Crystal structure of diphthine synthase from Pyrococcus horikoshii OT3
rcsb
source organism Pyrococcus horikoshii
molecule tags Transferase
molecule keywords diphthine synthase
total genus 82
structure length 265
sequence length 265
chains with identical sequence B
ec nomenclature ec 2.1.1.98: Diphthine synthase.
pdb deposition date 2006-07-28

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00590 TP_methylase Tetrapyrrole (Corrin/Porphyrin) Methylases
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.950.10 Alpha Beta 2-Layer Sandwich Methyltransferase, Cobalt-precorrin-4 Transmethylase; Domain 2 Methyltransferase, Cobalt-precorrin-4 Transmethylase; Domain 2 2dv7A02
3.40.1010.10 Alpha Beta 3-Layer(aba) Sandwich Cobalt-precorrin-4 Transmethylase; domain 1 Cobalt-precorrin-4 Transmethylase; Domain 1 2dv7A01
1PJTA 2P2XA 2EK7A 2E16A 1PJSA 2EK3A 2E4NA 2EJJA 2DSHA 2OWGA 3ND1A 2PCIA 2E4RA 2BB3A 2YBQA 4E16A 3HH1A 2ELEA 2EGLA 2QBUA 2E17A 2HUXA 2P5FA 3KWPA 3FFYA 2P5CA 2ED3A 2OWKA 2YBOA 2E0KA 1V9AA 2PB4A 2EJKA 2HUVA 3NEIA 2ELDA 2E15A 2DXVA 3NUTA 1VHVA 2EHCA 1PJQA 3I4TA 2PCKA 1CBFA 2DEKA 2EKAA 2DV4A 2EL1A 2EGSA 2PB5A 2P6KA 2ZVCA 1S4DA 2E0NA 2CBFA 2OWVA 2E07A 2DXWA 2Z6RA 2EL3A 2OWFA 2E08A 2E8QA 2HUTA 2PCAA 2P9DA 2EK4A 1VE2A 2NPNA 2E8SA 2E8RA 2HUQA 2P6LA 2EL0A 2PCHA 2EGBA 2DSIA 2EHLA 2DV7A 2DXXA 2PCGA 1WNGA 1WYZA 2EK2A 1WDEA 2E8HA 2ED5A 2EEQA 2DV3A 2DSGA 2DV5A 2PCMA 2EN5A 3FQ6A 2P6IA 2EJZA 2EH4A 2EMRA 2EMUA 2PB6A 2P6DA 2EH5A 2E7RA 2ENIA 5HW4A 1VA0A 3NDCA 2EH2A 2ZVBA 2HR8A 2OWUA 2EL2A 1VCEA
chains in the Genus database with same CATH superfamily
3KELA 1PJTA 2P2XA 3UV3A 2EK7A 4H4DA 2E16A 3SZOA 1PJSA 2EK3A 2E4NA 3TIXB 2EJJA 4EB3A 2DSHA 2OWGA 3ND1A 2PCIA 2E4RA 3UTCA 3ZGLA 2BB3A 2YBQA 4E16A 3HH1A 3KE9A 2ELEA 3ZGNA 2EGLA 2QBUA 2E17A 2HUXA 3LMMA 3T0FA 2P5FA 4H4CA 3KWPA 3FFYA 2P5CA 2ED3A 2OWKA 2YBOA 2E0KA 1V9AA 2PB4A 2EJKA 2HUVA 3NEIA 2ELDA 2E15A 2DXVA 3NUTA 1VHVA 2EHCA 1PJQA 3I4TA 2PCKA 1CBFA 2DEKA 2EKAA 2DV4A 3UV6A 4MV5A 2EL1A 2EGSA 2PB5A 2P6KA 3UV7A 2KYYA 2ZVCA 1S4DA 2E0NA 2CBFA 2OWVA 2E07A 3SZUA 2DXWA 2Z6RA 2EL3A 2OWFA 2E08A 2E8QA 2HUTA 2PCAA 2P9DA 2EK4A 1VE2A 2NPNA 2E8SA 2E8RA 2HUQA 2P6LA 2EL0A 2PCHA 2EGBA 2DSIA 3UTDA 2EHLA 2DV7A 4MUYA 2DXXA 2PCGA 1WNGA 1WYZA 2EK2A 1WDEA 2E8HA 2ED5A 2EEQA 2DV3A 4MUXA 2DSGA 4MV0A 2DV5A 2PCMA 2EN5A 3FQ6A 4H4EA 2P6IA 3SZLA 2EJZA 2EH4A 2EMRA 2EMUA 2PB6A 3UWMA 3F7TA 3URKA 2P6DA 2EH5A 2E7RA 2ENIA 5HW4A 1VA0A 3NDCA 2EH2A 2ZVBA 2HR8A 3KE8A 3KEFA 2OWUA 4N7BA 3T0GA 3DNFA 2EL2A 3KEMA 1VCEA
chains in the Genus database with same CATH topology
3KELA 1PJTA 2P2XA 3UV3A 2EK7A 4H4DA 2E16A 3SZOA 1PJSA 2EK3A 2E4NA 3TIXB 2EJJA 4EB3A 2DSHA 2OWGA 3ND1A 2PCIA 2E4RA 3UTCA 3ZGLA 2BB3A 2YBQA 4E16A 3HH1A 3KE9A 2ELEA 3ZGNA 2EGLA 2QBUA 2E17A 2HUXA 3LMMA 3T0FA 2P5FA 4H4CA 3KWPA 3FFYA 2P5CA 2ED3A 2OWKA 2YBOA 2E0KA 1V9AA 2PB4A 2EJKA 2HUVA 3NEIA 2ELDA 2E15A 2DXVA 3NUTA 1VHVA 2EHCA 1PJQA 3I4TA 2PCKA 1CBFA 2DEKA 2EKAA 2DV4A 3UV6A 4MV5A 2EL1A 2EGSA 2PB5A 2P6KA 3UV7A 2KYYA 2ZVCA 1S4DA 2E0NA 2CBFA 2OWVA 2E07A 3SZUA 2DXWA 2Z6RA 2EL3A 2OWFA 2E08A 2E8QA 2HUTA 2PCAA 2P9DA 2EK4A 1VE2A 2NPNA 2E8SA 2E8RA 2HUQA 2P6LA 2EL0A 2PCHA 2EGBA 2DSIA 3UTDA 2EHLA 2DV7A 4MUYA 2DXXA 2PCGA 1WNGA 1WYZA 2EK2A 1WDEA 2E8HA 2ED5A 2EEQA 2DV3A 4MUXA 2DSGA 4MV0A 2DV5A 2PCMA 2EN5A 3FQ6A 4H4EA 2P6IA 3SZLA 2EJZA 2EH4A 2EMRA 2EMUA 2PB6A 3UWMA 3F7TA 3URKA 2P6DA 2EH5A 2E7RA 2ENIA 5HW4A 1VA0A 3NDCA 2EH2A 2ZVBA 2HR8A 3KE8A 3KEFA 2OWUA 4N7BA 3T0GA 3DNFA 2EL2A 3KEMA 1VCEA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1PJT A;  2P2X A;  2EK7 A;  2E16 A;  1PJS A;  2EK3 A;  2E4N A;  2EJJ A;  2DSH A;  2OWG A;  3ND1 A;  2PCI A;  2E4R A;  2BB3 A;  2YBQ A;  4E16 A;  3HH1 A;  2ELE A;  2EGL A;  2QBU A;  2E17 A;  2HUX A;  2P5F A;  3KWP A;  3FFY A;  2P5C A;  2ED3 A;  2OWK A;  2YBO A;  2E0K A;  1V9A A;  2PB4 A;  2EJK A;  2HUV A;  3NEI A;  2ELD A;  2E15 A;  2DXV A;  3NUT A;  1VHV A;  2EHC A;  1PJQ A;  3I4T A;  2PCK A;  1CBF A;  2DEK A;  2EKA A;  2DV4 A;  2EL1 A;  2EGS A;  2PB5 A;  2P6K A;  2ZVC A;  1S4D A;  2E0N A;  2CBF A;  2OWV A;  2E07 A;  2DXW A;  2Z6R A;  2EL3 A;  2OWF A;  2E08 A;  2E8Q A;  2HUT A;  2PCA A;  2P9D A;  2EK4 A;  1VE2 A;  2NPN A;  2E8S A;  2E8R A;  2HUQ A;  2P6L A;  2EL0 A;  2PCH A;  2EGB A;  2DSI A;  2EHL A;  2DV7 A;  2DXX A;  2PCG A;  1WNG A;  1WYZ A;  2EK2 A;  1WDE A;  2E8H A;  2ED5 A;  2EEQ A;  2DV3 A;  2DSG A;  2DV5 A;  2PCM A;  2EN5 A;  3FQ6 A;  2P6I A;  2EJZ A;  2EH4 A;  2EMR A;  2EMU A;  2PB6 A;  2P6D A;  2EH5 A;  2E7R A;  2ENI A;  5HW4 A;  1VA0 A;  3NDC A;  2EH2 A;  2ZVB A;  2HR8 A;  2OWU A;  2EL2 A;  1VCE A; 
#chains in the Genus database with same CATH topology
 3KEL A;  1PJT A;  2P2X A;  3UV3 A;  2EK7 A;  4H4D A;  2E16 A;  3SZO A;  1PJS A;  2EK3 A;  2E4N A;  3TIX B;  2EJJ A;  4EB3 A;  2DSH A;  2OWG A;  3ND1 A;  2PCI A;  2E4R A;  3UTC A;  3ZGL A;  2BB3 A;  2YBQ A;  4E16 A;  3HH1 A;  3KE9 A;  2ELE A;  3ZGN A;  2EGL A;  2QBU A;  2E17 A;  2HUX A;  3LMM A;  3T0F A;  2P5F A;  4H4C A;  3KWP A;  3FFY A;  2P5C A;  2ED3 A;  2OWK A;  2YBO A;  2E0K A;  1V9A A;  2PB4 A;  2EJK A;  2HUV A;  3NEI A;  2ELD A;  2E15 A;  2DXV A;  3NUT A;  1VHV A;  2EHC A;  1PJQ A;  3I4T A;  2PCK A;  1CBF A;  2DEK A;  2EKA A;  2DV4 A;  3UV6 A;  4MV5 A;  2EL1 A;  2EGS A;  2PB5 A;  2P6K A;  3UV7 A;  2KYY A;  2ZVC A;  1S4D A;  2E0N A;  2CBF A;  2OWV A;  2E07 A;  3SZU A;  2DXW A;  2Z6R A;  2EL3 A;  2OWF A;  2E08 A;  2E8Q A;  2HUT A;  2PCA A;  2P9D A;  2EK4 A;  1VE2 A;  2NPN A;  2E8S A;  2E8R A;  2HUQ A;  2P6L A;  2EL0 A;  2PCH A;  2EGB A;  2DSI A;  3UTD A;  2EHL A;  2DV7 A;  4MUY A;  2DXX A;  2PCG A;  1WNG A;  1WYZ A;  2EK2 A;  1WDE A;  2E8H A;  2ED5 A;  2EEQ A;  2DV3 A;  4MUX A;  2DSG A;  4MV0 A;  2DV5 A;  2PCM A;  2EN5 A;  3FQ6 A;  4H4E A;  2P6I A;  3SZL A;  2EJZ A;  2EH4 A;  2EMR A;  2EMU A;  2PB6 A;  3UWM A;  3F7T A;  3URK A;  2P6D A;  2EH5 A;  2E7R A;  2ENI A;  5HW4 A;  1VA0 A;  3NDC A;  2EH2 A;  2ZVB A;  2HR8 A;  3KE8 A;  3KEF A;  2OWU A;  4N7B A;  3T0G A;  3DNF A;  2EL2 A;  3KEM A;  1VCE A; 
#chains in the Genus database with same CATH homology
 3KEL A;  1PJT A;  2P2X A;  3UV3 A;  2EK7 A;  4H4D A;  2E16 A;  3SZO A;  1PJS A;  2EK3 A;  2E4N A;  3TIX B;  2EJJ A;  4EB3 A;  2DSH A;  2OWG A;  3ND1 A;  2PCI A;  2E4R A;  3UTC A;  3ZGL A;  2BB3 A;  2YBQ A;  4E16 A;  3HH1 A;  3KE9 A;  2ELE A;  3ZGN A;  2EGL A;  2QBU A;  2E17 A;  2HUX A;  3LMM A;  3T0F A;  2P5F A;  4H4C A;  3KWP A;  3FFY A;  2P5C A;  2ED3 A;  2OWK A;  2YBO A;  2E0K A;  1V9A A;  2PB4 A;  2EJK A;  2HUV A;  3NEI A;  2ELD A;  2E15 A;  2DXV A;  3NUT A;  1VHV A;  2EHC A;  1PJQ A;  3I4T A;  2PCK A;  1CBF A;  2DEK A;  2EKA A;  2DV4 A;  3UV6 A;  4MV5 A;  2EL1 A;  2EGS A;  2PB5 A;  2P6K A;  3UV7 A;  2KYY A;  2ZVC A;  1S4D A;  2E0N A;  2CBF A;  2OWV A;  2E07 A;  3SZU A;  2DXW A;  2Z6R A;  2EL3 A;  2OWF A;  2E08 A;  2E8Q A;  2HUT A;  2PCA A;  2P9D A;  2EK4 A;  1VE2 A;  2NPN A;  2E8S A;  2E8R A;  2HUQ A;  2P6L A;  2EL0 A;  2PCH A;  2EGB A;  2DSI A;  3UTD A;  2EHL A;  2DV7 A;  4MUY A;  2DXX A;  2PCG A;  1WNG A;  1WYZ A;  2EK2 A;  1WDE A;  2E8H A;  2ED5 A;  2EEQ A;  2DV3 A;  4MUX A;  2DSG A;  4MV0 A;  2DV5 A;  2PCM A;  2EN5 A;  3FQ6 A;  4H4E A;  2P6I A;  3SZL A;  2EJZ A;  2EH4 A;  2EMR A;  2EMU A;  2PB6 A;  3UWM A;  3F7T A;  3URK A;  2P6D A;  2EH5 A;  2E7R A;  2ENI A;  5HW4 A;  1VA0 A;  3NDC A;  2EH2 A;  2ZVB A;  2HR8 A;  3KE8 A;  3KEF A;  2OWU A;  4N7B A;  3T0G A;  3DNF A;  2EL2 A;  3KEM A;  1VCE A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...