2DV7A

Crystal structure of lys187 to arg mutant of diphthine synthase
Total Genus 82
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
82
sequence length
265
structure length
265
Chain Sequence
MVLYFIGLGLYDERDITVKGLEIAKKCDYVFAEFYTSLMAGTTLGRIQKLIGKEIRVLSREDVELNFENIVLPLAKENDVAFLTPGDPLVATTHAELRIRAKRAGVESYVIHAPSIYSAVGITGLHIYKFGKSATVAYPEGNWFPTSYYDVIKENAERGLHTLLFLDIKAEKRMYMTANEAMELLLRVEDMKKGGVFTDDTLVVVLARAGSLNPTIRAGYVKDLIREDFGDPPHILIVPGKLHIVEAEYLVEIAGAPREILRVNV
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of diphthine synthase from Pyrococcus horikoshii OT3
rcsb
source organism Pyrococcus horikoshii
molecule tags Transferase
molecule keywords diphthine synthase
total genus 82
structure length 265
sequence length 265
chains with identical sequence B
ec nomenclature ec 2.1.1.98: Diphthine synthase.
pdb deposition date 2006-07-28

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00590 TP_methylase Tetrapyrrole (Corrin/Porphyrin) Methylases
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.950.10 Alpha Beta 2-Layer Sandwich Methyltransferase, Cobalt-precorrin-4 Transmethylase; Domain 2 Methyltransferase, Cobalt-precorrin-4 Transmethylase; Domain 2 2dv7A02
3.40.1010.10 Alpha Beta 3-Layer(aba) Sandwich Cobalt-precorrin-4 Transmethylase; domain 1 Cobalt-precorrin-4 Transmethylase; Domain 1 2dv7A01
2OWUA 2EKAA 2DXXA 2HUXA 2QBUA 2HUTA 2EL0A 2E8HA 2ELEA 2EGLA 2E17A 1PJQA 1S4DA 2BB3A 2P5FA 2PCIA 2EJJA 2EEQA 3NDCA 1CBFA 2PCHA 1VCEA 2PCKA 2PCGA 2DV4A 2DSHA 2E8QA 2EJKA 2DXWA 2OWFA 2P6LA 2OWVA 2EH4A 2EK2A 2P6DA 3FQ6A 1WDEA 3NEIA 2EK3A 2NPNA 2CBFA 1VHVA 1VA0A 2P5CA 1PJTA 2E4RA 2EJZA 2YBOA 2EH5A 2EMRA 2P6KA 2EL2A 2EK4A 2EHLA 1PJSA 1WYZA 2Z6RA 2ZVCA 3KWPA 2EL1A 2DXVA 2ED3A 2EGBA 1V9AA 2EK7A 2HR8A 5HW4A 2OWGA 2EL3A 2P2XA 2ENIA 2E0KA 2PB6A 2PB4A 2HUVA 2E07A 2ELDA 4E16A 2EHCA 3ND1A 2DV5A 2PB5A 3I4TA 3FFYA 2DV7A 2DV3A 3HH1A 2YBQA 2PCMA 2OWKA 2DEKA 2E08A 2E4NA 2E8SA 3NUTA 2DSIA 2DSGA 2E16A 2E15A 1VE2A 2EH2A 2P9DA 2E8RA 2P6IA 2E0NA 2ED5A 2EGSA 2E7RA 2PCAA 1WNGA 2EN5A 2EMUA 2ZVBA 2HUQA
chains in the Genus database with same CATH superfamily
2OWUA 2EKAA 4H4CA 3ZGLA 2DXXA 2HUXA 2QBUA 2HUTA 3SZOA 4N7BA 4EB3A 2EL0A 2E8HA 2ELEA 2EGLA 2E17A 1PJQA 3T0GA 1S4DA 2BB3A 4MUYA 2P5FA 2PCIA 2KYYA 2EJJA 2EEQA 3NDCA 4H4EA 1CBFA 2PCHA 1VCEA 2PCKA 2PCGA 2DV4A 3DNFA 2DSHA 2E8QA 2EJKA 2DXWA 3KEMA 2OWFA 3TIXB 2P6LA 3UV6A 2OWVA 2EH4A 2EK2A 2P6DA 3FQ6A 3UTDA 1WDEA 3NEIA 2EK3A 2NPNA 2CBFA 3UV3A 3KEFA 1VHVA 3LMMA 3F7TA 1VA0A 2P5CA 3UWMA 1PJTA 2E4RA 4MUXA 3SZLA 3URKA 2EJZA 2YBOA 2EH5A 2EMRA 2P6KA 3SZUA 2EL2A 2EK4A 4H4DA 2EHLA 3T0FA 3ZGNA 1PJSA 1WYZA 2Z6RA 2ZVCA 3KWPA 2EL1A 2DXVA 2ED3A 2EGBA 3UTCA 1V9AA 2EK7A 2HR8A 5HW4A 3KE8A 3KE9A 2OWGA 2EL3A 2P2XA 2ENIA 2E0KA 2PB6A 2PB4A 2HUVA 2E07A 2ELDA 4E16A 2EHCA 3ND1A 2DV5A 2PB5A 3I4TA 3FFYA 2DV7A 2DV3A 3HH1A 2YBQA 2PCMA 2OWKA 2DEKA 2E08A 4MV0A 3UV7A 2E4NA 2E8SA 3NUTA 2DSIA 2DSGA 2E16A 2E15A 1VE2A 2EH2A 2P9DA 2E8RA 2P6IA 2E0NA 3KELA 2ED5A 2EGSA 4MV5A 2E7RA 2PCAA 1WNGA 2EN5A 2EMUA 2ZVBA 2HUQA
chains in the Genus database with same CATH topology
2OWUA 2EKAA 4H4CA 3ZGLA 2DXXA 2HUXA 2QBUA 2HUTA 3SZOA 4N7BA 4EB3A 2EL0A 2E8HA 2ELEA 2EGLA 2E17A 1PJQA 3T0GA 1S4DA 2BB3A 4MUYA 2P5FA 2PCIA 2KYYA 2EJJA 2EEQA 3NDCA 4H4EA 1CBFA 2PCHA 1VCEA 2PCKA 2PCGA 2DV4A 3DNFA 2DSHA 2E8QA 2EJKA 2DXWA 3KEMA 2OWFA 3TIXB 2P6LA 3UV6A 2OWVA 2EH4A 2EK2A 2P6DA 3FQ6A 3UTDA 1WDEA 3NEIA 2EK3A 2NPNA 2CBFA 3UV3A 3KEFA 1VHVA 3LMMA 3F7TA 1VA0A 2P5CA 3UWMA 1PJTA 2E4RA 4MUXA 3SZLA 3URKA 2EJZA 2YBOA 2EH5A 2EMRA 2P6KA 3SZUA 2EL2A 2EK4A 4H4DA 2EHLA 3T0FA 3ZGNA 1PJSA 1WYZA 2Z6RA 2ZVCA 3KWPA 2EL1A 2DXVA 2ED3A 2EGBA 3UTCA 1V9AA 2EK7A 2HR8A 5HW4A 3KE8A 3KE9A 2OWGA 2EL3A 2P2XA 2ENIA 2E0KA 2PB6A 2PB4A 2HUVA 2E07A 2ELDA 4E16A 2EHCA 3ND1A 2DV5A 2PB5A 3I4TA 3FFYA 2DV7A 2DV3A 3HH1A 2YBQA 2PCMA 2OWKA 2DEKA 2E08A 4MV0A 3UV7A 2E4NA 2E8SA 3NUTA 2DSIA 2DSGA 2E16A 2E15A 1VE2A 2EH2A 2P9DA 2E8RA 2P6IA 2E0NA 3KELA 2ED5A 2EGSA 4MV5A 2E7RA 2PCAA 1WNGA 2EN5A 2EMUA 2ZVBA 2HUQA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2OWU A;  2EKA A;  2DXX A;  2HUX A;  2QBU A;  2HUT A;  2EL0 A;  2E8H A;  2ELE A;  2EGL A;  2E17 A;  1PJQ A;  1S4D A;  2BB3 A;  2P5F A;  2PCI A;  2EJJ A;  2EEQ A;  3NDC A;  1CBF A;  2PCH A;  1VCE A;  2PCK A;  2PCG A;  2DV4 A;  2DSH A;  2E8Q A;  2EJK A;  2DXW A;  2OWF A;  2P6L A;  2OWV A;  2EH4 A;  2EK2 A;  2P6D A;  3FQ6 A;  1WDE A;  3NEI A;  2EK3 A;  2NPN A;  2CBF A;  1VHV A;  1VA0 A;  2P5C A;  1PJT A;  2E4R A;  2EJZ A;  2YBO A;  2EH5 A;  2EMR A;  2P6K A;  2EL2 A;  2EK4 A;  2EHL A;  1PJS A;  1WYZ A;  2Z6R A;  2ZVC A;  3KWP A;  2EL1 A;  2DXV A;  2ED3 A;  2EGB A;  1V9A A;  2EK7 A;  2HR8 A;  5HW4 A;  2OWG A;  2EL3 A;  2P2X A;  2ENI A;  2E0K A;  2PB6 A;  2PB4 A;  2HUV A;  2E07 A;  2ELD A;  4E16 A;  2EHC A;  3ND1 A;  2DV5 A;  2PB5 A;  3I4T A;  3FFY A;  2DV7 A;  2DV3 A;  3HH1 A;  2YBQ A;  2PCM A;  2OWK A;  2DEK A;  2E08 A;  2E4N A;  2E8S A;  3NUT A;  2DSI A;  2DSG A;  2E16 A;  2E15 A;  1VE2 A;  2EH2 A;  2P9D A;  2E8R A;  2P6I A;  2E0N A;  2ED5 A;  2EGS A;  2E7R A;  2PCA A;  1WNG A;  2EN5 A;  2EMU A;  2ZVB A;  2HUQ A; 
#chains in the Genus database with same CATH topology
 2OWU A;  2EKA A;  4H4C A;  3ZGL A;  2DXX A;  2HUX A;  2QBU A;  2HUT A;  3SZO A;  4N7B A;  4EB3 A;  2EL0 A;  2E8H A;  2ELE A;  2EGL A;  2E17 A;  1PJQ A;  3T0G A;  1S4D A;  2BB3 A;  4MUY A;  2P5F A;  2PCI A;  2KYY A;  2EJJ A;  2EEQ A;  3NDC A;  4H4E A;  1CBF A;  2PCH A;  1VCE A;  2PCK A;  2PCG A;  2DV4 A;  3DNF A;  2DSH A;  2E8Q A;  2EJK A;  2DXW A;  3KEM A;  2OWF A;  3TIX B;  2P6L A;  3UV6 A;  2OWV A;  2EH4 A;  2EK2 A;  2P6D A;  3FQ6 A;  3UTD A;  1WDE A;  3NEI A;  2EK3 A;  2NPN A;  2CBF A;  3UV3 A;  3KEF A;  1VHV A;  3LMM A;  3F7T A;  1VA0 A;  2P5C A;  3UWM A;  1PJT A;  2E4R A;  4MUX A;  3SZL A;  3URK A;  2EJZ A;  2YBO A;  2EH5 A;  2EMR A;  2P6K A;  3SZU A;  2EL2 A;  2EK4 A;  4H4D A;  2EHL A;  3T0F A;  3ZGN A;  1PJS A;  1WYZ A;  2Z6R A;  2ZVC A;  3KWP A;  2EL1 A;  2DXV A;  2ED3 A;  2EGB A;  3UTC A;  1V9A A;  2EK7 A;  2HR8 A;  5HW4 A;  3KE8 A;  3KE9 A;  2OWG A;  2EL3 A;  2P2X A;  2ENI A;  2E0K A;  2PB6 A;  2PB4 A;  2HUV A;  2E07 A;  2ELD A;  4E16 A;  2EHC A;  3ND1 A;  2DV5 A;  2PB5 A;  3I4T A;  3FFY A;  2DV7 A;  2DV3 A;  3HH1 A;  2YBQ A;  2PCM A;  2OWK A;  2DEK A;  2E08 A;  4MV0 A;  3UV7 A;  2E4N A;  2E8S A;  3NUT A;  2DSI A;  2DSG A;  2E16 A;  2E15 A;  1VE2 A;  2EH2 A;  2P9D A;  2E8R A;  2P6I A;  2E0N A;  3KEL A;  2ED5 A;  2EGS A;  4MV5 A;  2E7R A;  2PCA A;  1WNG A;  2EN5 A;  2EMU A;  2ZVB A;  2HUQ A; 
#chains in the Genus database with same CATH homology
 2OWU A;  2EKA A;  4H4C A;  3ZGL A;  2DXX A;  2HUX A;  2QBU A;  2HUT A;  3SZO A;  4N7B A;  4EB3 A;  2EL0 A;  2E8H A;  2ELE A;  2EGL A;  2E17 A;  1PJQ A;  3T0G A;  1S4D A;  2BB3 A;  4MUY A;  2P5F A;  2PCI A;  2KYY A;  2EJJ A;  2EEQ A;  3NDC A;  4H4E A;  1CBF A;  2PCH A;  1VCE A;  2PCK A;  2PCG A;  2DV4 A;  3DNF A;  2DSH A;  2E8Q A;  2EJK A;  2DXW A;  3KEM A;  2OWF A;  3TIX B;  2P6L A;  3UV6 A;  2OWV A;  2EH4 A;  2EK2 A;  2P6D A;  3FQ6 A;  3UTD A;  1WDE A;  3NEI A;  2EK3 A;  2NPN A;  2CBF A;  3UV3 A;  3KEF A;  1VHV A;  3LMM A;  3F7T A;  1VA0 A;  2P5C A;  3UWM A;  1PJT A;  2E4R A;  4MUX A;  3SZL A;  3URK A;  2EJZ A;  2YBO A;  2EH5 A;  2EMR A;  2P6K A;  3SZU A;  2EL2 A;  2EK4 A;  4H4D A;  2EHL A;  3T0F A;  3ZGN A;  1PJS A;  1WYZ A;  2Z6R A;  2ZVC A;  3KWP A;  2EL1 A;  2DXV A;  2ED3 A;  2EGB A;  3UTC A;  1V9A A;  2EK7 A;  2HR8 A;  5HW4 A;  3KE8 A;  3KE9 A;  2OWG A;  2EL3 A;  2P2X A;  2ENI A;  2E0K A;  2PB6 A;  2PB4 A;  2HUV A;  2E07 A;  2ELD A;  4E16 A;  2EHC A;  3ND1 A;  2DV5 A;  2PB5 A;  3I4T A;  3FFY A;  2DV7 A;  2DV3 A;  3HH1 A;  2YBQ A;  2PCM A;  2OWK A;  2DEK A;  2E08 A;  4MV0 A;  3UV7 A;  2E4N A;  2E8S A;  3NUT A;  2DSI A;  2DSG A;  2E16 A;  2E15 A;  1VE2 A;  2EH2 A;  2P9D A;  2E8R A;  2P6I A;  2E0N A;  3KEL A;  2ED5 A;  2EGS A;  4MV5 A;  2E7R A;  2PCA A;  1WNG A;  2EN5 A;  2EMU A;  2ZVB A;  2HUQ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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