2DV7A

Crystal structure of lys187 to arg mutant of diphthine synthase
Total Genus 82
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
82
sequence length
265
structure length
265
Chain Sequence
b'MVLYFIGLGLYDERDITVKGLEIAKKCDYVFAEFYTSLMAGTTLGRIQKLIGKEIRVLSREDVELNFENIVLPLAKENDVAFLTPGDPLVATTHAELRIRAKRAGVESYVIHAPSIYSAVGITGLHIYKFGKSATVAYPEGNWFPTSYYDVIKENAERGLHTLLFLDIKAEKRMYMTANEAMELLLRVEDMKKGGVFTDDTLVVVLARAGSLNPTIRAGYVKDLIREDFGDPPHILIVPGKLHIVEAEYLVEIAGAPREILRVNV'
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords diphthine synthase
publication title Crystal structure of diphthine synthase from Pyrococcus horikoshii OT3
rcsb
source organism Pyrococcus horikoshii
molecule tags Transferase
total genus 82
structure length 265
sequence length 265
chains with identical sequence B
ec nomenclature ec 2.1.1.98: Diphthine synthase.
pdb deposition date 2006-07-28

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00590 TP_methylase Tetrapyrrole (Corrin/Porphyrin) Methylases
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.950.10 Alpha Beta 2-Layer Sandwich Methyltransferase, Cobalt-precorrin-4 Transmethylase; Domain 2 Methyltransferase, Cobalt-precorrin-4 Transmethylase; Domain 2 2dv7A02
3.40.1010.10 Alpha Beta 3-Layer(aba) Sandwich Cobalt-precorrin-4 Transmethylase; domain 1 Cobalt-precorrin-4 Transmethylase; Domain 1 2dv7A01
2EN5A 2HR8A 2DEKA 2DV7A 2OWKA 2PB4A 3NEIA 2EL3A 2P9DA 2NPNA 1PJSA 1PJQA 2E7RA 2EK4A 1WNGA 2DXXA 2OWGA 2E8HA 2P6DA 2QBUA 1S4DA 2EJJA 2P6KA 2P5CA 2P6LA 2E0NA 2ELEA 3NUTA 2OWUA 2DV4A 2E15A 2PCKA 2HUQA 1VA0A 4E16A 1CBFA 3FQ6A 2EGSA 2DSHA 2P6IA 2E8QA 2EGLA 2DV3A 2PCGA 2ED3A 2YBQA 2E4RA 2E08A 2HUXA 2OWFA 2E4NA 2ELDA 2ENIA 2E17A 3HH1A 2DSIA 2E8RA 2Z6RA 2EJKA 2DXVA 2EHLA 1V9AA 2EL0A 2E0KA 2BB3A 2P5FA 2PCAA 2DSGA 1VE2A 2EH4A 2PCMA 3ND1A 2E07A 2EEQA 2PB5A 2DV5A 2HUVA 2EK7A 2E8SA 3NDCA 2EHCA 2EMRA 3FFYA 5HW4A 2CBFA 2ZVCA 3I4TA 3KWPA 2OWVA 2EL1A 1VCEA 1PJTA 2EH5A 2EJZA 2EMUA 2PB6A 1VHVA 2EH2A 2EGBA 2EKAA 2ED5A 2DXWA 2P2XA 2PCHA 1WYZA 2EL2A 2PCIA 2HUTA 2ZVBA 2EK2A 2EK3A 2E16A 2YBOA 1WDEA
chains in the Genus database with same CATH superfamily
2EN5A 2HR8A 2DEKA 2DV7A 2OWKA 2PB4A 3NEIA 2EL3A 3LMMA 2P9DA 3F7TA 2NPNA 3T0GA 1PJSA 1PJQA 2E7RA 2EK4A 1WNGA 2DXXA 2OWGA 3KE8A 2E8HA 2P6DA 2QBUA 1S4DA 2EJJA 3KEMA 2P6KA 2P5CA 2P6LA 2E0NA 3SZUA 2ELEA 3NUTA 2OWUA 2DV4A 3TIXB 4H4DA 4MUXA 2E15A 2PCKA 3T0FA 2HUQA 1VA0A 4E16A 1CBFA 3FQ6A 2EGSA 2KYYA 3SZLA 2DSHA 2P6IA 2E8QA 2EGLA 2DV3A 2PCGA 3URKA 2ED3A 2YBQA 3UWMA 2E4RA 2E08A 2HUXA 2OWFA 4H4EA 2E4NA 3KELA 2ELDA 4MUYA 2ENIA 2E17A 3HH1A 2DSIA 3UTCA 3KE9A 2E8RA 2Z6RA 4MV0A 4N7BA 2EJKA 3ZGNA 2DXVA 2EHLA 1V9AA 2EL0A 4EB3A 2E0KA 2BB3A 2P5FA 2PCAA 2DSGA 1VE2A 2EH4A 2PCMA 3ND1A 3UV3A 2E07A 2EEQA 2PB5A 4H4CA 2DV5A 2HUVA 3UV7A 2EK7A 2E8SA 3NDCA 3UTDA 3UV6A 2EHCA 2EMRA 3FFYA 5HW4A 2CBFA 2ZVCA 4MV5A 3I4TA 3KWPA 3DNFA 2OWVA 2EL1A 1VCEA 1PJTA 2EH5A 2EJZA 3SZOA 2EMUA 2PB6A 1VHVA 2EH2A 2EGBA 3ZGLA 2EKAA 2ED5A 2DXWA 2P2XA 2PCHA 1WYZA 3KEFA 2EL2A 2PCIA 2HUTA 2ZVBA 2EK2A 2EK3A 2E16A 2YBOA 1WDEA
chains in the Genus database with same CATH topology
2EN5A 2HR8A 2DEKA 2DV7A 2OWKA 2PB4A 3NEIA 2EL3A 3LMMA 2P9DA 3F7TA 2NPNA 3T0GA 1PJSA 1PJQA 2E7RA 2EK4A 1WNGA 2DXXA 2OWGA 3KE8A 2E8HA 2P6DA 2QBUA 1S4DA 2EJJA 3KEMA 2P6KA 2P5CA 2P6LA 2E0NA 3SZUA 2ELEA 3NUTA 2OWUA 2DV4A 3TIXB 4H4DA 4MUXA 2E15A 2PCKA 3T0FA 2HUQA 1VA0A 4E16A 1CBFA 3FQ6A 2EGSA 2KYYA 3SZLA 2DSHA 2P6IA 2E8QA 2EGLA 2DV3A 2PCGA 3URKA 2ED3A 2YBQA 3UWMA 2E4RA 2E08A 2HUXA 2OWFA 4H4EA 2E4NA 3KELA 2ELDA 4MUYA 2ENIA 2E17A 3HH1A 2DSIA 3UTCA 3KE9A 2E8RA 2Z6RA 4MV0A 4N7BA 2EJKA 3ZGNA 2DXVA 2EHLA 1V9AA 2EL0A 4EB3A 2E0KA 2BB3A 2P5FA 2PCAA 2DSGA 1VE2A 2EH4A 2PCMA 3ND1A 3UV3A 2E07A 2EEQA 2PB5A 4H4CA 2DV5A 2HUVA 3UV7A 2EK7A 2E8SA 3NDCA 3UTDA 3UV6A 2EHCA 2EMRA 3FFYA 5HW4A 2CBFA 2ZVCA 4MV5A 3I4TA 3KWPA 3DNFA 2OWVA 2EL1A 1VCEA 1PJTA 2EH5A 2EJZA 3SZOA 2EMUA 2PB6A 1VHVA 2EH2A 2EGBA 3ZGLA 2EKAA 2ED5A 2DXWA 2P2XA 2PCHA 1WYZA 3KEFA 2EL2A 2PCIA 2HUTA 2ZVBA 2EK2A 2EK3A 2E16A 2YBOA 1WDEA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2EN5 A;  2HR8 A;  2DEK A;  2DV7 A;  2OWK A;  2PB4 A;  3NEI A;  2EL3 A;  2P9D A;  2NPN A;  1PJS A;  1PJQ A;  2E7R A;  2EK4 A;  1WNG A;  2DXX A;  2OWG A;  2E8H A;  2P6D A;  2QBU A;  1S4D A;  2EJJ A;  2P6K A;  2P5C A;  2P6L A;  2E0N A;  2ELE A;  3NUT A;  2OWU A;  2DV4 A;  2E15 A;  2PCK A;  2HUQ A;  1VA0 A;  4E16 A;  1CBF A;  3FQ6 A;  2EGS A;  2DSH A;  2P6I A;  2E8Q A;  2EGL A;  2DV3 A;  2PCG A;  2ED3 A;  2YBQ A;  2E4R A;  2E08 A;  2HUX A;  2OWF A;  2E4N A;  2ELD A;  2ENI A;  2E17 A;  3HH1 A;  2DSI A;  2E8R A;  2Z6R A;  2EJK A;  2DXV A;  2EHL A;  1V9A A;  2EL0 A;  2E0K A;  2BB3 A;  2P5F A;  2PCA A;  2DSG A;  1VE2 A;  2EH4 A;  2PCM A;  3ND1 A;  2E07 A;  2EEQ A;  2PB5 A;  2DV5 A;  2HUV A;  2EK7 A;  2E8S A;  3NDC A;  2EHC A;  2EMR A;  3FFY A;  5HW4 A;  2CBF A;  2ZVC A;  3I4T A;  3KWP A;  2OWV A;  2EL1 A;  1VCE A;  1PJT A;  2EH5 A;  2EJZ A;  2EMU A;  2PB6 A;  1VHV A;  2EH2 A;  2EGB A;  2EKA A;  2ED5 A;  2DXW A;  2P2X A;  2PCH A;  1WYZ A;  2EL2 A;  2PCI A;  2HUT A;  2ZVB A;  2EK2 A;  2EK3 A;  2E16 A;  2YBO A;  1WDE A; 
#chains in the Genus database with same CATH topology
 2EN5 A;  2HR8 A;  2DEK A;  2DV7 A;  2OWK A;  2PB4 A;  3NEI A;  2EL3 A;  3LMM A;  2P9D A;  3F7T A;  2NPN A;  3T0G A;  1PJS A;  1PJQ A;  2E7R A;  2EK4 A;  1WNG A;  2DXX A;  2OWG A;  3KE8 A;  2E8H A;  2P6D A;  2QBU A;  1S4D A;  2EJJ A;  3KEM A;  2P6K A;  2P5C A;  2P6L A;  2E0N A;  3SZU A;  2ELE A;  3NUT A;  2OWU A;  2DV4 A;  3TIX B;  4H4D A;  4MUX A;  2E15 A;  2PCK A;  3T0F A;  2HUQ A;  1VA0 A;  4E16 A;  1CBF A;  3FQ6 A;  2EGS A;  2KYY A;  3SZL A;  2DSH A;  2P6I A;  2E8Q A;  2EGL A;  2DV3 A;  2PCG A;  3URK A;  2ED3 A;  2YBQ A;  3UWM A;  2E4R A;  2E08 A;  2HUX A;  2OWF A;  4H4E A;  2E4N A;  3KEL A;  2ELD A;  4MUY A;  2ENI A;  2E17 A;  3HH1 A;  2DSI A;  3UTC A;  3KE9 A;  2E8R A;  2Z6R A;  4MV0 A;  4N7B A;  2EJK A;  3ZGN A;  2DXV A;  2EHL A;  1V9A A;  2EL0 A;  4EB3 A;  2E0K A;  2BB3 A;  2P5F A;  2PCA A;  2DSG A;  1VE2 A;  2EH4 A;  2PCM A;  3ND1 A;  3UV3 A;  2E07 A;  2EEQ A;  2PB5 A;  4H4C A;  2DV5 A;  2HUV A;  3UV7 A;  2EK7 A;  2E8S A;  3NDC A;  3UTD A;  3UV6 A;  2EHC A;  2EMR A;  3FFY A;  5HW4 A;  2CBF A;  2ZVC A;  4MV5 A;  3I4T A;  3KWP A;  3DNF A;  2OWV A;  2EL1 A;  1VCE A;  1PJT A;  2EH5 A;  2EJZ A;  3SZO A;  2EMU A;  2PB6 A;  1VHV A;  2EH2 A;  2EGB A;  3ZGL A;  2EKA A;  2ED5 A;  2DXW A;  2P2X A;  2PCH A;  1WYZ A;  3KEF A;  2EL2 A;  2PCI A;  2HUT A;  2ZVB A;  2EK2 A;  2EK3 A;  2E16 A;  2YBO A;  1WDE A; 
#chains in the Genus database with same CATH homology
 2EN5 A;  2HR8 A;  2DEK A;  2DV7 A;  2OWK A;  2PB4 A;  3NEI A;  2EL3 A;  3LMM A;  2P9D A;  3F7T A;  2NPN A;  3T0G A;  1PJS A;  1PJQ A;  2E7R A;  2EK4 A;  1WNG A;  2DXX A;  2OWG A;  3KE8 A;  2E8H A;  2P6D A;  2QBU A;  1S4D A;  2EJJ A;  3KEM A;  2P6K A;  2P5C A;  2P6L A;  2E0N A;  3SZU A;  2ELE A;  3NUT A;  2OWU A;  2DV4 A;  3TIX B;  4H4D A;  4MUX A;  2E15 A;  2PCK A;  3T0F A;  2HUQ A;  1VA0 A;  4E16 A;  1CBF A;  3FQ6 A;  2EGS A;  2KYY A;  3SZL A;  2DSH A;  2P6I A;  2E8Q A;  2EGL A;  2DV3 A;  2PCG A;  3URK A;  2ED3 A;  2YBQ A;  3UWM A;  2E4R A;  2E08 A;  2HUX A;  2OWF A;  4H4E A;  2E4N A;  3KEL A;  2ELD A;  4MUY A;  2ENI A;  2E17 A;  3HH1 A;  2DSI A;  3UTC A;  3KE9 A;  2E8R A;  2Z6R A;  4MV0 A;  4N7B A;  2EJK A;  3ZGN A;  2DXV A;  2EHL A;  1V9A A;  2EL0 A;  4EB3 A;  2E0K A;  2BB3 A;  2P5F A;  2PCA A;  2DSG A;  1VE2 A;  2EH4 A;  2PCM A;  3ND1 A;  3UV3 A;  2E07 A;  2EEQ A;  2PB5 A;  4H4C A;  2DV5 A;  2HUV A;  3UV7 A;  2EK7 A;  2E8S A;  3NDC A;  3UTD A;  3UV6 A;  2EHC A;  2EMR A;  3FFY A;  5HW4 A;  2CBF A;  2ZVC A;  4MV5 A;  3I4T A;  3KWP A;  3DNF A;  2OWV A;  2EL1 A;  1VCE A;  1PJT A;  2EH5 A;  2EJZ A;  3SZO A;  2EMU A;  2PB6 A;  1VHV A;  2EH2 A;  2EGB A;  3ZGL A;  2EKA A;  2ED5 A;  2DXW A;  2P2X A;  2PCH A;  1WYZ A;  3KEF A;  2EL2 A;  2PCI A;  2HUT A;  2ZVB A;  2EK2 A;  2EK3 A;  2E16 A;  2YBO A;  1WDE A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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