2DXWA

Crystal structure of glu54 to lys mutant of diphthine synthase
Total Genus 85
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
85
sequence length
265
structure length
265
Chain Sequence
MVLYFIGLGLYDERDITVKGLEIAKKCDYVFAEFYTSLMAGTTLGRIQKLIGKKIRVLSREDVELNFENIVLPLAKENDVAFLTPGDPLVATTHAELRIRAKRAGVESYVIHAPSIYSAVGITGLHIYKFGKSATVAYPEGNWFPTSYYDVIKENAERGLHTLLFLDIKAEKRMYMTANEAMELLLKVEDMKKGGVFTDDTLVVVLARAGSLNPTIRAGYVKDLIREDFGDPPHILIVPGKLHIVEAEYLVEIAGAPREILRVNV
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of diphthine synthase from Pyrococcus horikoshii OT3
rcsb
source organism Pyrococcus horikoshii
molecule tags Transferase
molecule keywords diphthine synthase
total genus 85
structure length 265
sequence length 265
chains with identical sequence B
ec nomenclature ec 2.1.1.98: Diphthine synthase.
pdb deposition date 2006-08-31

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00590 TP_methylase Tetrapyrrole (Corrin/Porphyrin) Methylases
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.950.10 Alpha Beta 2-Layer Sandwich Methyltransferase, Cobalt-precorrin-4 Transmethylase; Domain 2 Methyltransferase, Cobalt-precorrin-4 Transmethylase; Domain 2 2dxwA02
3.40.1010.10 Alpha Beta 3-Layer(aba) Sandwich Cobalt-precorrin-4 Transmethylase; domain 1 Cobalt-precorrin-4 Transmethylase; Domain 1 2dxwA01
2OWGA 2PB6A 2P5FA 1WDEA 2DV5A 3KWPA 2E0NA 2EMUA 2YBOA 2Z6RA 2OWVA 2YBQA 2ELDA 2DEKA 2EL0A 1PJTA 2DXWA 2EL3A 2HUVA 2EK2A 1VHVA 1S4DA 2OWFA 2ENIA 2E4RA 2EH2A 1VCEA 2ED5A 2HR8A 5HW4A 2OWUA 2E16A 2EGBA 2EL1A 1V9AA 2DXVA 2EMRA 2P6LA 2ZVCA 2DV4A 4E16A 2EK4A 2EGLA 2OWKA 2QBUA 2PCMA 1WNGA 2DSIA 2HUXA 3ND1A 2PCGA 2DV3A 2PCKA 2EHCA 3I4TA 2BB3A 2E15A 2P5CA 2EH4A 2P2XA 2E07A 1PJQA 2PCAA 3NUTA 3FQ6A 2P6KA 1CBFA 2E8HA 2PB4A 3HH1A 2DXXA 2E7RA 2DV7A 2HUQA 2EK7A 2EJZA 2E8QA 2E0KA 2EEQA 2DSHA 2P6DA 2E8RA 2P9DA 2EHLA 2EK3A 1VE2A 2EKAA 2EH5A 2E4NA 2P6IA 2E8SA 2PCHA 2NPNA 2E17A 2PB5A 1WYZA 2DSGA 2EJKA 2ED3A 2HUTA 2E08A 1PJSA 2EN5A 2EJJA 2ELEA 2CBFA 3NEIA 2ZVBA 2EGSA 1VA0A 2PCIA 3NDCA 2EL2A 3FFYA
chains in the Genus database with same CATH superfamily
2OWGA 2PB6A 2P5FA 1WDEA 2DV5A 3KWPA 2E0NA 2EMUA 2YBOA 2Z6RA 2OWVA 2YBQA 2ELDA 4MV0A 2DEKA 2EL0A 1PJTA 2DXWA 4H4DA 3UTDA 3T0GA 2EL3A 2HUVA 2EK2A 1VHVA 1S4DA 2OWFA 2ENIA 3UTCA 2E4RA 2EH2A 1VCEA 2ED5A 2HR8A 3DNFA 3TIXB 5HW4A 2OWUA 2E16A 2EGBA 2EL1A 1V9AA 2DXVA 2EMRA 2P6LA 2ZVCA 3UV7A 2DV4A 3UV3A 4E16A 2EK4A 2EGLA 2OWKA 4H4EA 2QBUA 2PCMA 1WNGA 2DSIA 2HUXA 3KEMA 4N7BA 3ND1A 4MV5A 2PCGA 2DV3A 2PCKA 2EHCA 3I4TA 2BB3A 3KE9A 2E15A 2P5CA 2EH4A 3URKA 2P2XA 2E07A 3LMMA 3KELA 1PJQA 3SZOA 2PCAA 3NUTA 3FQ6A 2P6KA 3SZLA 1CBFA 2E8HA 2PB4A 3ZGNA 3KE8A 3HH1A 2DXXA 2E7RA 2DV7A 2HUQA 3UWMA 3F7TA 2EK7A 2EJZA 2E8QA 2E0KA 2EEQA 2DSHA 2P6DA 2E8RA 2P9DA 2EHLA 2EK3A 1VE2A 2EKAA 3SZUA 2EH5A 2E4NA 2P6IA 2KYYA 2E8SA 2PCHA 2NPNA 2E17A 2PB5A 1WYZA 2DSGA 2EJKA 3T0FA 2ED3A 2HUTA 4MUXA 4EB3A 2E08A 1PJSA 2EN5A 2EJJA 3ZGLA 2ELEA 2CBFA 3NEIA 3KEFA 2ZVBA 4H4CA 3UV6A 2EGSA 1VA0A 2PCIA 4MUYA 3NDCA 2EL2A 3FFYA
chains in the Genus database with same CATH topology
2OWGA 2PB6A 2P5FA 1WDEA 2DV5A 3KWPA 2E0NA 2EMUA 2YBOA 2Z6RA 2OWVA 2YBQA 2ELDA 4MV0A 2DEKA 2EL0A 1PJTA 2DXWA 4H4DA 3UTDA 3T0GA 2EL3A 2HUVA 2EK2A 1VHVA 1S4DA 2OWFA 2ENIA 3UTCA 2E4RA 2EH2A 1VCEA 2ED5A 2HR8A 3DNFA 3TIXB 5HW4A 2OWUA 2E16A 2EGBA 2EL1A 1V9AA 2DXVA 2EMRA 2P6LA 2ZVCA 3UV7A 2DV4A 3UV3A 4E16A 2EK4A 2EGLA 2OWKA 4H4EA 2QBUA 2PCMA 1WNGA 2DSIA 2HUXA 3KEMA 4N7BA 3ND1A 4MV5A 2PCGA 2DV3A 2PCKA 2EHCA 3I4TA 2BB3A 3KE9A 2E15A 2P5CA 2EH4A 3URKA 2P2XA 2E07A 3LMMA 3KELA 1PJQA 3SZOA 2PCAA 3NUTA 3FQ6A 2P6KA 3SZLA 1CBFA 2E8HA 2PB4A 3ZGNA 3KE8A 3HH1A 2DXXA 2E7RA 2DV7A 2HUQA 3UWMA 3F7TA 2EK7A 2EJZA 2E8QA 2E0KA 2EEQA 2DSHA 2P6DA 2E8RA 2P9DA 2EHLA 2EK3A 1VE2A 2EKAA 3SZUA 2EH5A 2E4NA 2P6IA 2KYYA 2E8SA 2PCHA 2NPNA 2E17A 2PB5A 1WYZA 2DSGA 2EJKA 3T0FA 2ED3A 2HUTA 4MUXA 4EB3A 2E08A 1PJSA 2EN5A 2EJJA 3ZGLA 2ELEA 2CBFA 3NEIA 3KEFA 2ZVBA 4H4CA 3UV6A 2EGSA 1VA0A 2PCIA 4MUYA 3NDCA 2EL2A 3FFYA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2OWG A;  2PB6 A;  2P5F A;  1WDE A;  2DV5 A;  3KWP A;  2E0N A;  2EMU A;  2YBO A;  2Z6R A;  2OWV A;  2YBQ A;  2ELD A;  2DEK A;  2EL0 A;  1PJT A;  2DXW A;  2EL3 A;  2HUV A;  2EK2 A;  1VHV A;  1S4D A;  2OWF A;  2ENI A;  2E4R A;  2EH2 A;  1VCE A;  2ED5 A;  2HR8 A;  5HW4 A;  2OWU A;  2E16 A;  2EGB A;  2EL1 A;  1V9A A;  2DXV A;  2EMR A;  2P6L A;  2ZVC A;  2DV4 A;  4E16 A;  2EK4 A;  2EGL A;  2OWK A;  2QBU A;  2PCM A;  1WNG A;  2DSI A;  2HUX A;  3ND1 A;  2PCG A;  2DV3 A;  2PCK A;  2EHC A;  3I4T A;  2BB3 A;  2E15 A;  2P5C A;  2EH4 A;  2P2X A;  2E07 A;  1PJQ A;  2PCA A;  3NUT A;  3FQ6 A;  2P6K A;  1CBF A;  2E8H A;  2PB4 A;  3HH1 A;  2DXX A;  2E7R A;  2DV7 A;  2HUQ A;  2EK7 A;  2EJZ A;  2E8Q A;  2E0K A;  2EEQ A;  2DSH A;  2P6D A;  2E8R A;  2P9D A;  2EHL A;  2EK3 A;  1VE2 A;  2EKA A;  2EH5 A;  2E4N A;  2P6I A;  2E8S A;  2PCH A;  2NPN A;  2E17 A;  2PB5 A;  1WYZ A;  2DSG A;  2EJK A;  2ED3 A;  2HUT A;  2E08 A;  1PJS A;  2EN5 A;  2EJJ A;  2ELE A;  2CBF A;  3NEI A;  2ZVB A;  2EGS A;  1VA0 A;  2PCI A;  3NDC A;  2EL2 A;  3FFY A; 
#chains in the Genus database with same CATH topology
 2OWG A;  2PB6 A;  2P5F A;  1WDE A;  2DV5 A;  3KWP A;  2E0N A;  2EMU A;  2YBO A;  2Z6R A;  2OWV A;  2YBQ A;  2ELD A;  4MV0 A;  2DEK A;  2EL0 A;  1PJT A;  2DXW A;  4H4D A;  3UTD A;  3T0G A;  2EL3 A;  2HUV A;  2EK2 A;  1VHV A;  1S4D A;  2OWF A;  2ENI A;  3UTC A;  2E4R A;  2EH2 A;  1VCE A;  2ED5 A;  2HR8 A;  3DNF A;  3TIX B;  5HW4 A;  2OWU A;  2E16 A;  2EGB A;  2EL1 A;  1V9A A;  2DXV A;  2EMR A;  2P6L A;  2ZVC A;  3UV7 A;  2DV4 A;  3UV3 A;  4E16 A;  2EK4 A;  2EGL A;  2OWK A;  4H4E A;  2QBU A;  2PCM A;  1WNG A;  2DSI A;  2HUX A;  3KEM A;  4N7B A;  3ND1 A;  4MV5 A;  2PCG A;  2DV3 A;  2PCK A;  2EHC A;  3I4T A;  2BB3 A;  3KE9 A;  2E15 A;  2P5C A;  2EH4 A;  3URK A;  2P2X A;  2E07 A;  3LMM A;  3KEL A;  1PJQ A;  3SZO A;  2PCA A;  3NUT A;  3FQ6 A;  2P6K A;  3SZL A;  1CBF A;  2E8H A;  2PB4 A;  3ZGN A;  3KE8 A;  3HH1 A;  2DXX A;  2E7R A;  2DV7 A;  2HUQ A;  3UWM A;  3F7T A;  2EK7 A;  2EJZ A;  2E8Q A;  2E0K A;  2EEQ A;  2DSH A;  2P6D A;  2E8R A;  2P9D A;  2EHL A;  2EK3 A;  1VE2 A;  2EKA A;  3SZU A;  2EH5 A;  2E4N A;  2P6I A;  2KYY A;  2E8S A;  2PCH A;  2NPN A;  2E17 A;  2PB5 A;  1WYZ A;  2DSG A;  2EJK A;  3T0F A;  2ED3 A;  2HUT A;  4MUX A;  4EB3 A;  2E08 A;  1PJS A;  2EN5 A;  2EJJ A;  3ZGL A;  2ELE A;  2CBF A;  3NEI A;  3KEF A;  2ZVB A;  4H4C A;  3UV6 A;  2EGS A;  1VA0 A;  2PCI A;  4MUY A;  3NDC A;  2EL2 A;  3FFY A; 
#chains in the Genus database with same CATH homology
 2OWG A;  2PB6 A;  2P5F A;  1WDE A;  2DV5 A;  3KWP A;  2E0N A;  2EMU A;  2YBO A;  2Z6R A;  2OWV A;  2YBQ A;  2ELD A;  4MV0 A;  2DEK A;  2EL0 A;  1PJT A;  2DXW A;  4H4D A;  3UTD A;  3T0G A;  2EL3 A;  2HUV A;  2EK2 A;  1VHV A;  1S4D A;  2OWF A;  2ENI A;  3UTC A;  2E4R A;  2EH2 A;  1VCE A;  2ED5 A;  2HR8 A;  3DNF A;  3TIX B;  5HW4 A;  2OWU A;  2E16 A;  2EGB A;  2EL1 A;  1V9A A;  2DXV A;  2EMR A;  2P6L A;  2ZVC A;  3UV7 A;  2DV4 A;  3UV3 A;  4E16 A;  2EK4 A;  2EGL A;  2OWK A;  4H4E A;  2QBU A;  2PCM A;  1WNG A;  2DSI A;  2HUX A;  3KEM A;  4N7B A;  3ND1 A;  4MV5 A;  2PCG A;  2DV3 A;  2PCK A;  2EHC A;  3I4T A;  2BB3 A;  3KE9 A;  2E15 A;  2P5C A;  2EH4 A;  3URK A;  2P2X A;  2E07 A;  3LMM A;  3KEL A;  1PJQ A;  3SZO A;  2PCA A;  3NUT A;  3FQ6 A;  2P6K A;  3SZL A;  1CBF A;  2E8H A;  2PB4 A;  3ZGN A;  3KE8 A;  3HH1 A;  2DXX A;  2E7R A;  2DV7 A;  2HUQ A;  3UWM A;  3F7T A;  2EK7 A;  2EJZ A;  2E8Q A;  2E0K A;  2EEQ A;  2DSH A;  2P6D A;  2E8R A;  2P9D A;  2EHL A;  2EK3 A;  1VE2 A;  2EKA A;  3SZU A;  2EH5 A;  2E4N A;  2P6I A;  2KYY A;  2E8S A;  2PCH A;  2NPN A;  2E17 A;  2PB5 A;  1WYZ A;  2DSG A;  2EJK A;  3T0F A;  2ED3 A;  2HUT A;  4MUX A;  4EB3 A;  2E08 A;  1PJS A;  2EN5 A;  2EJJ A;  3ZGL A;  2ELE A;  2CBF A;  3NEI A;  3KEF A;  2ZVB A;  4H4C A;  3UV6 A;  2EGS A;  1VA0 A;  2PCI A;  4MUY A;  3NDC A;  2EL2 A;  3FFY A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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